torafugu

Summary

Alias: takifugu rubripes, fugu rubripes

Top Publications

  1. ncbi Lectins homologous to those of monocotyledonous plants in the skin mucus and intestine of pufferfish, Fugu rubripes
    Shigeyuki Tsutsui
    Fisheries Laboratory, The University of Tokyo, Shizuoka 431 0211, Japan
    J Biol Chem 278:20882-9. 2003
  2. ncbi Intron loss in the SART1 genes of Fugu rubripes and Tetraodon nigroviridis
    D J Bolland
    Institute of Genetics, Queen s Medical Centre, University of Nottingham, Nottingham, NG7 2UH, UK
    Gene 271:43-9. 2001
  3. ncbi Functional characterisation and genomic analysis of an epithelial calcium channel (ECaC) from pufferfish, Fugu rubripes
    Andong Qiu
    School of Health and Life Sciences, King s College London, Division of Life Sciences, Franklin Wilkins Building, 150 Stamford Street, London SE1 9NN, United Kingdom
    Gene 342:113-23. 2004
  4. ncbi Origin of INSL3-mediated testicular descent in therian mammals
    Jae Il Park
    Division of Reproductive Biology, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, California 94305 5317, USA
    Genome Res 18:974-85. 2008
  5. ncbi Origin and diversity of the SOX transcription factor gene family: genome-wide analysis in Fugu rubripes
    Peter Koopman
    Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland 4072, Australia
    Gene 328:177-86. 2004
  6. ncbi Characterization of the transcription factor MTF-1 from the Japanese pufferfish (Fugu rubripes) reveals evolutionary conservation of heavy metal stress response
    A Auf der Maur
    Institut für Molekularbiologie der Universität Zürich, Switzerland
    Biol Chem 380:175-85. 1999
  7. ncbi A practical approach to phylogenomics: the phylogeny of ray-finned fish (Actinopterygii) as a case study
    Chenhong Li
    School of Biological Sciences, University of Nebraska, Lincoln, NE 68588, USA
    BMC Evol Biol 7:44. 2007
  8. ncbi Many genes in fish have species-specific asymmetric rates of molecular evolution
    Dirk Steinke
    Lehrstuhl fur Zoologie und Evolutionsbiologie, Department of Biology, University of Konstanz, D 78457 Konstanz, Germany
    BMC Genomics 7:20. 2006
  9. ncbi Molecular evolution of the vertebrate blood coagulation network
    Colin J Davidson
    Haemostasis Group, MRC Clinical Sciences Centre, The Faculty of Medicine, Imperial College, Hammersmith Hospital Campus, London, UK
    Thromb Haemost 89:420-8. 2003
  10. ncbi The comparative genomic structure and sequence of the surfeit gene homologs in the puffer fish Fugu rubripes and their association with CpG-rich islands
    N Armes
    Eukaryotic Gene Organisation and Expression Laboratory, Imperial Cancer Research Fund, Lincoln s Inn Fields, London WC2A 3PX, UK
    Genome Res 7:1138-52. 1997

Research Grants

  1. MOLECULAR ANALYSIS IN ALAGILLE SYNDROME
    Ian Krantz; Fiscal Year: 2002
  2. Fugu Promoters for Mammalian Cortical Neurons
    EDWARD CALLAWAY; Fiscal Year: 2006
  3. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin Hughes; Fiscal Year: 2007
  4. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin Hughes; Fiscal Year: 2009
  5. AHR signaling in Mammalian and Non-Mammalian Models
    Mark E Hahn; Fiscal Year: 2011
  6. Generation of an In Vivo Human Genome Enhancer Dataset
    LEN ALEXANDER PENNACCHIO; Fiscal Year: 2010
  7. Generation of an In Vivo Human Genome Transcriptional Enhancer Dataset
    Len Pennacchio; Fiscal Year: 2009
  8. A High-Resolution Enhancer Atlas of the Developing Forebrain
    LEN ALEXANDER PENNACCHIO; Fiscal Year: 2010
  9. Mechanisms of Embryo Response to Oxidative Stress
    Mark E Hahn; Fiscal Year: 2010
  10. Gene Delivery in Retinal Diseases
    John M Nickerson; Fiscal Year: 2010

Detail Information

Publications143 found, 100 shown here

  1. ncbi Lectins homologous to those of monocotyledonous plants in the skin mucus and intestine of pufferfish, Fugu rubripes
    Shigeyuki Tsutsui
    Fisheries Laboratory, The University of Tokyo, Shizuoka 431 0211, Japan
    J Biol Chem 278:20882-9. 2003
    We have characterized pufflectin, a novel mannose-specific lectin, from the skin mucus of the pufferfish, Fugu rubripes. Molecular mass estimations by gel filtration and matrix-assisted laser desorption ionization time-of-flight mass ..
  2. ncbi Intron loss in the SART1 genes of Fugu rubripes and Tetraodon nigroviridis
    D J Bolland
    Institute of Genetics, Queen s Medical Centre, University of Nottingham, Nottingham, NG7 2UH, UK
    Gene 271:43-9. 2001
    ..examined the genomic structure and cDNA sequence of the SART1 gene in the compact genomes of the pufferfish Fugu rubripes and Tetraodon nigroviridis...
  3. ncbi Functional characterisation and genomic analysis of an epithelial calcium channel (ECaC) from pufferfish, Fugu rubripes
    Andong Qiu
    School of Health and Life Sciences, King s College London, Division of Life Sciences, Franklin Wilkins Building, 150 Stamford Street, London SE1 9NN, United Kingdom
    Gene 342:113-23. 2004
    ..mammalian epithelial calcium channels, ECaC1 (TRPV5) and ECaC2 (TRPV6), was cloned from gill of pufferfish (Fugu rubripes) and characterised, demonstrating that this gene predates the evolution of land-living vertebrates. The F...
  4. ncbi Origin of INSL3-mediated testicular descent in therian mammals
    Jae Il Park
    Division of Reproductive Biology, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, California 94305 5317, USA
    Genome Res 18:974-85. 2008
    ....
  5. ncbi Origin and diversity of the SOX transcription factor gene family: genome-wide analysis in Fugu rubripes
    Peter Koopman
    Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland 4072, Australia
    Gene 328:177-86. 2004
    ..We have now analysed the Sox gene complement in the pufferfish, Fugu rubripes, in order to shed further light on the diversity and origins of the Sox gene family...
  6. ncbi Characterization of the transcription factor MTF-1 from the Japanese pufferfish (Fugu rubripes) reveals evolutionary conservation of heavy metal stress response
    A Auf der Maur
    Institut für Molekularbiologie der Universität Zürich, Switzerland
    Biol Chem 380:175-85. 1999
    The pufferfish Fugu rubripes was recently introduced as a new model organism for genomic studies, since it contains a full set of vertebrate genes but only 13% as much DNA as a mammal...
  7. ncbi A practical approach to phylogenomics: the phylogeny of ray-finned fish (Actinopterygii) as a case study
    Chenhong Li
    School of Biological Sciences, University of Nebraska, Lincoln, NE 68588, USA
    BMC Evol Biol 7:44. 2007
    ..We report here a genome-comparison strategy to identifying nuclear gene markers for phylogenetic inference and apply it to the ray-finned fishes--the largest vertebrate clade in need of phylogenetic resolution...
  8. ncbi Many genes in fish have species-specific asymmetric rates of molecular evolution
    Dirk Steinke
    Lehrstuhl fur Zoologie und Evolutionsbiologie, Department of Biology, University of Konstanz, D 78457 Konstanz, Germany
    BMC Genomics 7:20. 2006
    ..We studied a set of 2466 genes that were present in Danio rerio, Takifugu rubripes, Tetraodon nigroviridis and Oryzias latipes to test (i) for forces of positive Darwinian selection; (ii) how ..
  9. ncbi Molecular evolution of the vertebrate blood coagulation network
    Colin J Davidson
    Haemostasis Group, MRC Clinical Sciences Centre, The Faculty of Medicine, Imperial College, Hammersmith Hospital Campus, London, UK
    Thromb Haemost 89:420-8. 2003
    ..sequence identity to the blood coagulation serine proteases and cofactors from chicken and the puffer fish (Fugu rubripes)...
  10. ncbi The comparative genomic structure and sequence of the surfeit gene homologs in the puffer fish Fugu rubripes and their association with CpG-rich islands
    N Armes
    Eukaryotic Gene Organisation and Expression Laboratory, Imperial Cancer Research Fund, Lincoln s Inn Fields, London WC2A 3PX, UK
    Genome Res 7:1138-52. 1997
    The puffer fish Fugu rubripes (Fugu) has a compact genome approximately one-seventh the size of man, mainly owing to small intron size and the presence of few dispersed repetitive DNA elements, which greatly facilitates the study of its ..
  11. ncbi Effect of dietary ascorbic acid on growth and non-specific immune responses of tiger puffer, Takifugu rubripes
    Jinee Eo
    Department of Marine Life Science, Cheju National University, Jeju 690 756, South Korea
    Fish Shellfish Immunol 25:611-6. 2008
    ..This study aimed to examine the essentiality and requirements of AA in diets for the tiger puffer, Takifugu rubripes based on growth performance, liver AA and bone collagen concentration, and non-specific immune responses...
  12. ncbi Experimental infection of several fish species with the causative agent of Kuchijirosho (snout ulcer disease) derived from the tiger puffer Takifugu rubripes
    T Miyadai
    Department of Marine Bioscience, Fukui Prefectural University, Obama, Japan
    Dis Aquat Organ 47:193-9. 2001
    Kuchijirosho (snout ulcer disease) is a fatal epidemic disease which affects the tiger puffer, Takifugu rubripes, a commercial fish species in Japan and Korea...
  13. ncbi Aberrant processing of the Fugu HD (FrHD) mRNA in mouse cells and in transgenic mice
    K Sathasivam
    Division of Medical and Molecular Genetics, UMDS, Guy s Hospital, London SE1 9RT, UK
    Hum Mol Genet 6:2141-9. 1997
    The puffer fish ( Fugu rubripes ) has a compact genome of 400 Mbp which is approximately 7.5-fold smaller than the human genome...
  14. ncbi Comparative proteomics of kidney samples from puffer fish Takifugu rubripes exposed to excessive fluoride: an insight into molecular response to fluorosis
    Jian Lu
    Institute of Life Sciences, Jiangsu University, No 301 Xuefu Road, Zhenjiang City, PR China
    Toxicol Mech Methods 20:345-54. 2010
    ....
  15. ncbi Interphotoreceptor retinoid-binding protein gene structure in tetrapods and teleost fish
    John M Nickerson
    Ophthalmology Department, Emory University, Atlanta, GA 30322, USA
    Mol Vis 12:1565-85. 2006
    ..Our goals were to gain insight into the function of IRBP, and to test the current model for the evolution of IRBP, in which Repeats were replicated from a simpler ancestral gene...
  16. ncbi Molecular cloning of EDG-3 and N-Shc genes from the puffer fish, Fugu rubripes, and conservation of synteny with the human genome
    F Yamaguchi
    The Molecular Sciences Institute, 2168 Shattuck Avenue, Berkeley, CA 94704, USA
    FEBS Lett 459:105-10. 1999
    ..4% similarity with the human protein. We mapped the human N-Shc gene to chromosome 9q21.3-q22.2. This is the first report of the genomic structure and the linkage of these two genes conserved between Fugu and human...
  17. ncbi Statistical information characterization of conserved non-coding elements in vertebrates
    I Abnizova
    MRC BSU, Robinson Way, Cambridge, UK
    J Bioinform Comput Biol 5:533-47. 2007
    ..elements (CNEs) has been derived from a comparison between the genomes of the puffer fish, Takifugu or Fugu rubripes, and man...
  18. ncbi Identification and characterization of the zebrafish and fugu genes encoding tuberoinfundibular peptide 39
    Madhusudhan R Papasani
    Department of Biological Sciences, Illinois State University, Normal, Illinois 61790, USA
    Endocrinology 145:5294-304. 2004
    ..with the zebrafish PTHR (zPTH2R) and human PTH2Rs and to determine its tissue-specific expression, fugu (Takifugu rubripes) and zebrafish (Danio rerio) genomic databases were screened with human TIP39 (hTIP39) sequences...
  19. ncbi Pan-vertebrate toll-like receptors during evolution
    Hiroyuki Oshiumi
    Department of Microbiology and Immunology, Hokkaido University Graduate School of Medicine, Sapporo 060 8638, Japan
    Curr Genomics 9:488-93. 2008
    ..According to Takifugu rubripes genome project, the puffer fish possesses fish-specific TLR21 and 22...
  20. ncbi Piscine PTHrP regulation of calcium and phosphate transport in winter flounder renal proximal tubule primary cultures
    Pedro M Guerreiro
    Centre of Marine Sciences, Universidade do Algarve, 8005 139 Faro, Portugal
    Am J Physiol Regul Integr Comp Physiol 299:R603-11. 2010
    ..The effects of an NH(2)-terminal peptide (amino acids 1-34) of Takifugu rubripes parathyroid hormone-related protein, (1-34)PTHrP, on Ca(2+) and P(i) transport were investigated in winter ..
  21. ncbi Evolution of the relaxin-like peptide family
    Tracey N Wilkinson
    Howard Florey Institute of Experimental Physiology and Medicine, University of Melbourne, Australia
    BMC Evol Biol 5:14. 2005
    ....
  22. ncbi Short-range linkage relationships of the valyl-tRNA synthetase gene in Fugu rubripes
    E H Lim
    Molecular Genetics, Level 5, Department of Medicine, Addenbrookes Hospital, Cambridge CB2 2QQ, UK
    Immunogenetics 46:332-6. 1997
    ..To extend this analysis further in another non-mammalian vertebrate, the compact genome of Fugu rubripes was investigated for the existence of orthologues of these class III genes and their relative arrangements...
  23. ncbi Involvement of host recognition by oncomiracidia and post-larval survivability in the host specificity of Heterobothrium okamotoi (Monogenea: Diclidophoridae)
    Yu Ohhashi
    Department of Aquatic Biosciences, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Yayoi 1 1 1, Bunkyo ku, Tokyo 113 8657, Japan
    Int J Parasitol 37:53-60. 2007
    Heterobothrium okamotoi, a monogenean gill parasite, shows high host specificity for tiger puffer, Takifugu rubripes. In the present study, in vivo and in vitro experimental infections were conducted using various fish species, including ..
  24. ncbi Comparative proteomics analysis of cardiac muscle samples from pufferfish Takifugu rubripes exposed to excessive fluoride: initial molecular response to fluorosis
    Jian Lu
    Institute of Life Sciences, Jiangsu University, Zhenjiang, 212013, PR China
    Toxicol Mech Methods 19:468-75. 2009
    Comparative proteomics was performed to identify proteins in the cardiac muscle of Takifugu rubripes in initial response to excessive fluoride. Sixteen fish were randomly divided into a control group and an experimental group...
  25. ncbi Proceedings of the SMBE Tri-National Young Investigators' Workshop 2005. Lineage-specific expansions and contractions of the bitter taste receptor gene repertoire in vertebrates
    Yasuhiro Go
    Department of Biosystems Science, The Graduate University for Advanced Studies Sokendai, Hayama, Kanagawa, Japan
    Mol Biol Evol 23:964-72. 2006
    ..domestica), amphibians (frogs, Xenopus tropicalis), and fishes (zebrafishes, Danio rerio; and pufferfishes, Takifugu rubripes) to investigate the birth-and-death process of T2R genes throughout vertebrate evolution...
  26. ncbi Comparison of the yeast proteome to other fungal genomes to find core fungal genes
    Tom Hsiang
    Department of Environmental Biology, University of Guelph, Guelph, Ontario, NIG 2W1, Canada
    J Mol Evol 60:475-83. 2005
    ..By comparing these common fungal genes to complete genomes of animals (Fugu rubripes, Caenorhabditis elegans), plants (Arabidopsis thaliana, Oryza sativa), and bacteria (Agrobacterium tumefaciens,..
  27. ncbi Strong conservation of the human NF2 locus based on sequence comparison in five species
    Caisa M Hansson
    Department of Genetics and Pathology, Rudbeck Laboratory, 3rd Floor, Dag Hammarskjöds väg 20, Uppsala University, 751 85 Uppsala, Sweden
    Mamm Genome 14:526-36. 2003
    ..2 ( NF2) tumor suppressor locus and orthologous loci from baboon, mouse, rat, and pufferfish Takifugu rubripes. A predominant feature of human-rodent conservation is a very similar distribution of conserved islands, ..
  28. ncbi Molecular evolutionary analysis of the widespread piggyBac transposon family and related "domesticated" sequences
    A Sarkar
    Center for Tropical Disease Research and Training, Department of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556 0369, USA
    Mol Genet Genomics 270:173-80. 2003
    ..to piggyBac have previously been identified from organisms such as humans ( Looper), the pufferfish Takifugu rubripes ( Pigibaku), Xenopus ( Tx), Daphnia ( Pokey), and the Oriental fruit fly Bactrocera dorsalis...
  29. ncbi Putative pheromone receptors related to the Ca2+-sensing receptor in Fugu
    T Naito
    Pharmaceutical Frontier Research Laboratories, Japan Tobacco, Inc, 13 2 Fukuura 1 chome, Kanazawa Ku, Yokohama, Kanagawa 236 Japan
    Proc Natl Acad Sci U S A 95:5178-81. 1998
    ..probing, we have isolated a large family of genes related to the Ca2+-sensing receptor from the genome of Fugu rubripes. One of the genes (type I) is the Fugu homologue of the Ca2+-sensing receptor...
  30. ncbi C-type lectin-like domains in Fugu rubripes
    Alex N Zelensky
    Computational Proteomics and Therapy Design Group, John Curtin School of Medical Research, Australian National University, PO Box 334, Canberra, ACT 2601, Australia
    BMC Genomics 5:51. 2004
    ..Three genome-level studies on human, C. elegans and D. melanogaster reported previously demonstrated almost complete divergence among invertebrate and mammalian families of CTLD-containing proteins (CTLDcps)...
  31. ncbi The melanocortin system in Fugu: determination of POMC/AGRP/MCR gene repertoire and synteny, as well as pharmacology and anatomical distribution of the MCRs
    Janis Klovins
    Department of Neuroscience, Uppsala University, Uppsala, Sweden
    Mol Biol Evol 21:563-79. 2004
    ..We performed a comprehensive characterization of the MC system in Fugu (Takifugu rubripes)...
  32. ncbi The invertebrate ancestry of endocannabinoid signalling: an orthologue of vertebrate cannabinoid receptors in the urochordate Ciona intestinalis
    Maurice R Elphick
    School of Biological Sciences, Queen Mary, University of London, E1 4NS, London, UK
    Gene 302:95-101. 2003
    ..mammals, birds, amphibians and fish, whilst CB(2) genes have been identified in mammals and in the puffer fish Fugu rubripes. Therefore, both CB(1) and CB(2) receptors probably occur throughout the vertebrates...
  33. ncbi Evolutionary origins of the endocannabinoid system
    John M McPartland
    GW Pharmaceuticals, 53 Washington Street Ext, Middlebury, VT 05753, USA
    Gene 370:64-74. 2006
    ..orthologs in the genomes of twelve phylogenetically diverse organisms: Homo sapiens, Mus musculus, Takifugu rubripes, Ciona intestinalis, Caenorhabditis elegans, Drosophila melanogaster, Saccharomyces cerevisiae, Arabidopsis ..
  34. ncbi Genomics, evolution, and expression of TBPL2, a member of the TBP family
    Cinzia Di Pietro
    Dipartimento di Scienze Biomediche Unità di Biologia Genetica e BioInformatica, Universita di Catania, Catania, Italy, EU
    DNA Cell Biol 26:369-85. 2007
    ..in Homo sapiens, Pan troglodytes, Mus musculus, Rattus norvegicus, Gallus gallus, Xenopus tropicalis, and Takifugu rubripes; (ii) its evolution and phylogenetic relationship with TBP, TBPL1, and TRF; (iii) the structure of the TBPL2 ..
  35. ncbi Endocannabinoids affect the reproductive functions in teleosts and amphibians
    E Cottone
    Dipartimento di Biologia Animale e dell Uomo, Laboratorio di Anatomia Comparata, Universita degli Studi di Torino, Via Accademia Albertina 13, I 10123 Torino, Italy
    Mol Cell Endocrinol 286:S41-5. 2008
    Following the discovery in the brain of the bonyfish Fugu rubripes of two genes encoding for type 1 cannabinoid receptors (CB1A and CB1B), investigations on the phylogeny of these receptors have indicated that the cannabinergic system is ..
  36. ncbi Analysis of the spermine synthase gene region in Fugu rubripes, Tetraodon fluviatilis, and Danio rerio
    A Boeddrich
    Max Planck Institut fur Molekulare Genetik, Ihnestrasse 73, Berlin Dahlem, D 14195, Germany
    Genomics 57:164-8. 1999
    ..1. We show that whereas the human gene spans a genomic region of 54 kb, the Fugu rubripes gene is encompassed in a 4.7-kb region...
  37. ncbi Short and long peptidoglycan recognition proteins (PGRPs) in zebrafish, with findings of multiple PGRP homologs in teleost fish
    M X Chang
    State Key Laboratory of Freshwater Ecology and Biotechnology, and Laboratory of Fish Diseases, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, Hubei Province 430072, PR China
    Mol Immunol 44:3005-23. 2007
    ..protein (PGRP) like genes have been discovered in fish including zebrafish Danio rerio, Japanese pufferfish TakiFugu rubripes and spotted green pufferfish Tetraodon nigroviridis...
  38. ncbi Positive feedback of hepatic angiotensinogen expression in silver sea bream (Sparus sarba)
    Marty K S Wong
    Department of Biology, The Chinese University of Hong Kong, Shatin, N T, Hong Kong SAR, China
    Mol Cell Endocrinol 263:103-11. 2007
    ..sarba only exhibits a fair resemblance to other fish angiotensinogens and shows 76.6% similarity to that of Takifugu rubripes and 57.2% similarity to that of Danio rerio...
  39. ncbi Developmental study of the shortened spinal cord in the adult tiger puffer fish, Takifugu rubripes (Teleostei)
    M Uehara
    Department of Veterinary Anatomy, Faculty of Agriculture, Tottori University, Tottori, Japan
    J Morphol 244:15-22. 2000
    ..While the spinal cord extends the entire length of the vertebral canal in the adult tiger puffer, Takifugu rubripes, the cord proper is greatly reduced in length and almost all of the canal is occupied by the filum terminale,..
  40. ncbi First molluscan transcription factor activator protein-1 (Ap-1) member from disk abalone and its expression profiling against immune challenge and tissue injury
    Mahanama De Zoysa
    Department of Marine Life Sciences, School of Biomedical Sciences, Jeju National University, Jeju Special Self Governing Province, Republic of Korea
    Fish Shellfish Immunol 29:1028-36. 2010
    ..The AbAp-1 shares 46, 43 and, 40% amino acid identities with fish (Takifugu rubripes), human and insect (Ixodes scapularis) Ap-1, respectively...
  41. ncbi Impacts of diclidophorid monogenean infections on fisheries in Japan
    Kazuo Ogawa
    Department of Aquatic Bioscience, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Yayoi, Bunkyo, 113 8657, Tokyo, Japan
    Int J Parasitol 32:373-80. 2002
    ..Heterobothrium okamotoi infects the gills and wall of the branchial cavity of the tiger puffer, Takifugu rubripes (Tetraodontidae), which is widely cultured in western Japan...
  42. ncbi Global identification and comparative analysis of SOCS genes in fish: insights into the molecular evolution of SOCS family
    Hong Jian Jin
    College of Life Sciences, Zhejiang University, Hangzhou 310058, China
    Mol Immunol 45:1258-68. 2008
    ..genes were identified, including 55 SOCS genes from five fish species, Tetraodon nigroviridis, Danio rerio, Takifugu rubripes, Gasterosteus aculeatus and Oryzias latipes, 11 from amphibian, avian and insects...
  43. ncbi Genetic basis of tetrodotoxin resistance in pufferfishes
    Byrappa Venkatesh
    Institute of Molecular and Cell Biology, 61 Biopolis Drive, 138673, Singapore
    Curr Biol 15:2069-72. 2005
    ..the genetic basis of TTX resistance in pufferfishes by comparing the sodium channels from two pufferfishes (Takifugu rubripes [fugu] and Tetraodon nigroviridis) and the TTX-sensitive zebrafish...
  44. ncbi Fugu (Takifugu rubripes) sexual differentiation: CYP19 regulation and aromatase inhibitor induced testicular development
    H Rashid
    Laboratory of Marine Biology, Faculty of Agriculture, Kyushu University, Hakozaki, Higashi ku, Fukuoka, Japan
    Sex Dev 1:311-22. 2007
    ..isoforms and endogenous sex steroids in gonadal sex differentiation and development of the Japanese fugu (Takifugu rubripes), an aromatase inhibitor (AI, fadrozole) was administered to developing fishes from the 'first feeding' till ..
  45. ncbi Characterization of the pufferfish Takifugu rubripes apolipoprotein multigene family
    Hidehiro Kondo
    Laboratory of Aquatic Molecular Biology and Biotechnology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo, Tokyo 113 8657, Japan
    Gene 346:257-66. 2005
    We have characterized the apolipoprotein multigene family of the pufferfish Takifugu rubripes. The pufferfish mainly contains 28-kDa, 27-kDa, and 14-kDa apolipoproteins in its plasma and was designated apo-28 kDa, apo-27 kDa, and apo-14 ..
  46. ncbi Change in tetrodotoxin content of the puffer fish Takifugu rubripes during seed production from fertilized eggs to juveniles
    Yuji Nagashima
    Department of Food Science and Technology, Tokyo University of Marine Science and Technology, 4 5 7 Konan, Minato, Tokyo 108 8477, Japan
    Shokuhin Eiseigaku Zasshi 51:48-51. 2010
    Changes in tetrodotoxin (TTX) content of the puffer fish Takifugu rubripes during seed production were examined. Two mature female puffer fish T. rubripes (samples 1 and 2) that contained TTX were used...
  47. ncbi Rh glycoprotein expression is modulated in pufferfish (Takifugu rubripes) during high environmental ammonia exposure
    C Michele Nawata
    Department of Biology, McMaster University, Hamilton, ON, Canada, L8S 4K1
    J Exp Biol 213:3150-60. 2010
    ..Passive processes and/or Rhbg and Rhcg2 in the pavement cells may maintain basal levels of plasma ammonia but elevated levels may require active excretion via NKA and Rhcg1 in the MRCs...
  48. ncbi Calcium mobilization from fish scales is mediated by parathyroid hormone related protein via the parathyroid hormone type 1 receptor
    J Rotllant
    CCMAR, CIMAR Laboratório Associado, Campus de Gambelas, 8005 139 Faro, Portugal
    Regul Pept 132:33-40. 2005
    ..A synthetic peptide (10(-8) M) based on the N-terminal 1-34 amino acid residues of Fugu rubripes PTHrP strongly stimulated cAMP synthesis and [3H]myo-inositol incorporation in sea bream scales...
  49. ncbi Analysis and characterization of the expression of the secretory and membrane forms of IgM heavy chains in the pufferfish, Takifugu rubripes
    Nil Ratan Saha
    Department of Aquatic Biosciences, Fisheries Laboratory, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Maisaka 2971 4, Shizuoka 431 0211, Japan
    Mol Immunol 42:113-24. 2005
    We investigated the structure and expression of immunoglobulin genes in the pufferfish, Takifugu rubripes, a highly prized and economically important fish species...
  50. ncbi Evaluation of hepatic uptake clearance of tetrodotoxin in the puffer fish Takifugu rubripes
    Takuya Matsumoto
    Department of Food Science and Technology, Tokyo University of Marine Science and Technology, Konan 4 5 7, Minato, Tokyo 108 8477, Japan
    Toxicon 52:369-74. 2008
    ..we investigated the hepatic uptake clearance (CL(uptake)) of tetrodotoxin (TTX) in the marine puffer fish Takifugu rubripes by integration plot analysis after a single bolus injection of 0...
  51. ncbi Phylogenetic analysis of the tenascin gene family: evidence of origin early in the chordate lineage
    R P Tucker
    Department of Cell Biology and Human Anatomy, University of California at Davis, Davis, CA 95616, USA
    BMC Evol Biol 6:60. 2006
    ..them, the tenascin genes of the urochordate Ciona intestinalis, the pufferfish Tetraodon nigroviridis and Takifugu rubripes and the frog Xenopus tropicalis were identified and their gene organization and predicted protein products ..
  52. ncbi Ligand-dependent transcriptional activities of four torafugu pufferfish Takifugu rubripes peroxisome proliferator-activated receptors
    Hidehiro Kondo
    Laboratory of Aquatic Molecular Biology and Biotechnology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo, Tokyo 113 8657, Japan
    Gen Comp Endocrinol 154:120-7. 2007
    ..receptors (PPARs), PPARalpha1, PPARalpha2, PPARbeta, and PPARgamma, from torafugu pufferfish Takifugu rubripes and determined for their transcriptional activity by the reporter assay using reporter plasmids containing ..
  53. ncbi Pharmacokinetics of tetrodotoxin in puffer fish Takifugu rubripes by a single administration technique
    Takuya Matsumoto
    Department of Food Science and Technology, Tokyo University of Marine Science and Technology, Konan 4 5 7, Minato, Tokyo 108 8477, Japan
    Toxicon 51:1051-9. 2008
    ..In this study, we examined the pharmacokinetics of TTX in Takifugu rubripes by a single administration under general anesthesia at 20 degrees C for 300 min...
  54. ncbi Differential gene expression profile in the liver of the marine puffer fish Takifugu rubripes induced by intramuscular administration of tetrodotoxin
    Takuya Matsumoto
    Department of Food Science and Technology, Tokyo University of Marine Science and Technology, 4 5 7 Konan, Minato, Tokyo 108 8477, Japan
    Toxicon 57:304-10. 2011
    ..of the marine puffer fish, we examined the hepatic gene expression profile of the marine puffer fish Takifugu rubripes by suppression subtractive hybridization in response to the intramuscular administration of 0...
  55. ncbi Efficacy of puffer fish (Takifugu rubripes) sauce in reducing hydroxyl radical damage to DNA assessed using the apurinic/apyrimidinic site method
    Kazuki Harada
    Department of Food Science and Technology, National Fisheries University, Independent Administrative Institution, The Ministry of Agriculture, Forestry and Fisheries of Japan, Yamaguchi 759 6595, Japan
    Int J Mol Med 20:309-14. 2007
    ..resonance (ESR) method as a standard method, we examined whether fish and soy sauces including puffer fish [Takifugu rubripes (Temminck et Schlegel)] sauce could protect DNA from damage caused by hydroxyl radicals...
  56. ncbi Involvement of carrier-mediated transport system in uptake of tetrodotoxin into liver tissue slices of puffer fish Takifugu rubripes
    Takuya Matsumoto
    Department of Food Science and Technology, Tokyo University of Marine Science and Technology, Konan 4 5 7, Minato, Tokyo 108 8477, Japan
    Toxicon 50:173-9. 2007
    ..In the present study, uptake of TTX into the liver tissue slices of puffer fish Takifugu rubripes was investigated by in vitro incubation experiment. When T...
  57. ncbi En bloc duplications, mutation rates, and densities of amino acid changes clarify the evolution of vertebrate alpha-1,3/4-fucosyltransferases
    Daniel Petit
    INRA, UMR 1061, Universite de Limoges, 123 Avenue Albert Thomas, Limoges, F 87060, GDR CNRS 2590, France
    J Mol Evol 63:353-64. 2006
    ..roles of duplications and mutations, we have compared amino acid sequences representative of bony fish (Takifugu rubripes), amphibians (Xenopus laevis), birds (Gallus gallus), and mammals (Bos taurus)...
  58. ncbi Fibre type-specific expression patterns of myosin heavy chain genes in adult torafugu Takifugu rubripes muscles
    D B Akolkar
    Department of Aquatic Bioscience, Graduate School of Agriculture and Life Sciences, The University of Tokyo, Bunkyo, Tokyo 113 8657, Japan
    J Exp Biol 213:137-45. 2010
    ..based on the total fugu genome database, which was the first to appear in fish, revealed that torafugu Takifugu rubripes contains 20 sarcomeric myosin heavy chain (MYH) genes (MYH genes) (Ikeda et al., 2007)...
  59. ncbi A novel BDNF gene promoter directs expression to skeletal muscle
    Gerhard Heinrich
    Medical Service, VA Northern California Health Care System, 150 Muir Road, Martinez, CA 94553, USA
    BMC Neurosci 4:11. 2003
    ..The molecular mechanisms that are responsible for tissue and cell-specific expression of these promoters are still incompletely understood...
  60. ncbi Structure and evolution of the teleost extraretinal rod-like opsin (errlo) and ocular rod opsin (rho) genes: is teleost rho a retrogene?
    James Bellingham
    Gene Targeting Unit, Department of Neuromuscular Diseases, Division of Neuroscience, Imperial College London, Charing Cross Hospital, St Dunstan s Road, London, W6 8RP, United Kingdom
    J Exp Zool B Mol Dev Evol 297:1-10. 2003
    ..exo-rhodopsin) gene, errlo (which is expressed uniquely in the pineal), in the puffer-fish, Fugu rubripes (Takifugu rubripes)...
  61. ncbi Mucus pH of the tiger puffer Takifugu rubripes is an important factor for host identification by the monogenean Heterobothrium okamotoi
    N Hirazawa
    Marine Biological Technology Center, Nippon Suisan Kaisha, Ltd, 508 8 Ariakeura, Tsurumi cho, Minamiamabegun, Oita 8 76 1204, Japan
    Parasitology 127:225-30. 2003
    ..H. okamotoi oncomiracidia attached preferentially to gill filaments and skin mucus from the tiger puffer Takifugu rubripes compared with corresponding material from other tested fishes (amber jack Seriola dumerili, red sea bream ..
  62. ncbi Differential expression of Na+-Cl- cotransporter and Na+-K+-Cl- cotransporter 2 in the distal nephrons of euryhaline and seawater pufferfishes
    Akira Kato
    Dept of Biological Sciences, Tokyo Institute of Technology, 4259 B 19 Nagatsuta cho, Midori ku, Yokohama 226 8501, Japan
    Am J Physiol Regul Integr Comp Physiol 300:R284-97. 2011
    ..On the other hand, the kidney of seawater pufferfish (torafugu, Takifugu rubripes), which lacked distal tubules, expressed very low levels of NCC, and, in the collecting ducts, high levels ..
  63. ncbi Uneven evolutionary rates of bradykinin B1 and B2 receptors in vertebrate lineages
    T Bromée
    Department of Neuroscience, Pharmacology, Uppsala University, P O Box 593, SE 751 24 Uppsala, Sweden
    Gene 373:100-8. 2006
    ..the bradykinin precursor in three species of bony fish (the zebrafish Danio rerio, the Japanese pufferfish Takifugu rubripes, and the green spotted pufferfish Tetraodon nigroviridis) and chicken and analyze the relationships to ..
  64. ncbi Early vertebrate chromosome duplications and the evolution of the neuropeptide Y receptor gene regions
    Tomas A Larsson
    Department of Neuroscience, Uppsala University, Box 593, 75124 Uppsala, Sweden
    BMC Evol Biol 8:184. 2008
    ..vertebrate genomes, 45 gene families with members close to the NPY receptor genes in the compact genomes of the teleost fishes Tetraodon nigroviridis and Takifugu rubripes. These correspond to Homo sapiens chromosomes 4, 5, 8 and 10.
  65. ncbi Changes of gonadal CB1 cannabinoid receptor mRNA in the gilthead seabream, Sparus aurata, during sex reversal
    B Ruggeri
    Dipartimento di Scienze Morfologiche e Biochimiche Comparate, Universita degli Studi di Camerino, Via Camerini 2, 62032 Camerino MC, Italy
    Gen Comp Endocrinol 150:263-9. 2007
    ..genes (CB1-like), named CB1A and CB1B, have been isolated in teleost fish, specifically in the puffer fish, Fugu rubripes. However, information on the physiological roles, such as the control of reproduction and development in fish ..
  66. ncbi Identification and phylogenetic analyses of the protein arginine methyltransferase gene family in fish and ascidians
    Chuan Mao Hung
    Institute of Medicine, Chung Shan Medical University, 110 Sec 1, Chein Kuo North Road, Taichung, Taiwan, ROC
    Gene 340:179-87. 2004
    ..In this study orthologues of eight human PRMT genes (PRMT1-7 and HRMT1L3) were identified in both puffer fish Fugu rubripes and zebrafish Danio rerio...
  67. ncbi Differential regulation of multiple alternatively spliced transcripts of MyoD
    Jorge M O Fernandes
    School of Biology, University of St Andrews, St Andrews, Fife KY16 8LB, UK
    Gene 391:178-85. 2007
    ..and characterization of three alternative transcripts of a myoD paralogue from the tiger pufferfish (Takifugu rubripes). The T...
  68. ncbi Identification and analysis of additional copies of the platelet-derived growth factor receptor and colony stimulating factor 1 receptor genes in fugu
    Hawys Williams
    Institute of Molecular and Cell Biology, 30 Medical Drive, 117609, Singapore
    Gene 295:255-64. 2002
    ..We have previously cloned the PDGFRbeta and CSF1R genes from the pufferfish, Fugu rubripes, and shown that they are tandemly linked like the mammalian genes [Genome Res. 6 (1996) 1185]...
  69. ncbi Characterization of three genes, AKAP84, BAW and WSB1, located 3' to the neurofibromatosis type 1 locus in Fugu rubripes
    H Kehrer-Sawatzki
    Department of Human Genetics, University of Ulm, Albert Einstein Allee 11, 89081, Ulm, Germany
    Gene 235:1-11. 1999
    Sequence analysis of cosmid clones was instrumental to identify three genes in the region flanking the Fugu rubripes NF1 gene in the 3' direction: the AKAP84 gene (A-kinase anchor protein 84), the WSB1 gene (WD-40-repeat protein with a ..
  70. ncbi Characterization of the pufferfish Otx2 cis-regulators reveals evolutionarily conserved genetic mechanisms for vertebrate head specification
    Chiharu Kimura-Yoshida
    Head Organizer Project, Vertebrate Body Plan Group, RIKEN Center for Developmental Biology, 2 2 3 Minatojima minami cho, Chuou ku, Kobe, Hyougo 650 0047, Japan
    Development 131:57-71. 2004
    ..In this study, the Otx2 genome of the puffer fish Fugu rubripes, which has been proposed as a model vertebrate owing to its highly compact genome, was cloned...
  71. ncbi Carbohydrate-binding site of a novel mannose-specific lectin from fugu (Takifugu rubripes) skin mucus
    Shigeyuki Tsutsui
    Fisheries Laboratory, The University of Tokyo, Shizuoka 431 0211, Japan
    Comp Biochem Physiol B Biochem Mol Biol 143:514-9. 2006
    Pufflectin-s, identified in the skin mucus of the fugu Takifugu rubripes, is a novel mannose-specific lectin with similar structure to monocotyledonous plant lectins...
  72. ncbi Alternative splicing in teleost fish genomes: same-species and cross-species analysis and comparisons
    Jianguo Lu
    The Fish Molecular Genetics and Biotechnology Laboratory, Aquatic Genomics Unit, Department of Fisheries and Allied Aquacultures and Program of Cell and Molecular Biosciences, Auburn University, Auburn, AL 36849, USA
    Mol Genet Genomics 283:531-9. 2010
    ..to study AS in four genome-enabled species (Danio rerio, Oryzias latipes, Gasterosteus aculeatus, and Takifugu rubripes) and one species lacking a complete genome sequence, Ictalurus punctatus...
  73. ncbi Subfunctionalization of expression and peptide domains following the ancient duplication of the proopiomelanocortin gene in teleost fishes
    Flavio S J de Souza
    Instituto de Investigaciones en Ingenieria Genetica y Biologia Molecular, CONICET, FCEyN, Universidad de Buenos Aires, Argentina
    Mol Biol Evol 22:2417-27. 2005
    ..By searching public genome projects, we have found that Tetraodon (Tetraodon nigroviridis), Fugu (Takifugu rubripes), and zebrafish (Danio rerio) possess two POMC genes, which we called POMCalpha and POMCbeta, and we present ..
  74. ncbi Different phylogenomic approaches to resolve the evolutionary relationships among model fish species
    Enrico Negrisolo
    Department of Public Health, Comparative Pathology and Veterinary Hygiene, University of Padova, Agripolis, Legnaro, Italy
    Mol Biol Evol 27:2757-74. 2010
    ..draft genome sequences for five model species (Danio rerio, Gasterosteus aculeatus, Oryzias latipes, Takifugu rubripes, and Tetraodon nigroviridis), and several others are in the finishing lane...
  75. ncbi Functional expression of a low-affinity zinc uptake transporter (FrZIP2) from pufferfish (Takifugu rubripes) in MDCK cells
    Andong Qiu
    King s College London, Nutritional Sciences Research Division, Franklin Wilkins Building, 150 Stamford Street, London SE1 9NH, UK
    Biochem J 390:777-86. 2005
    ..we reported on zinc uptake transporters from zebrafish (Danio rerio; DrZIP1) and Fugu pufferfish (Takifugu rubripes; FrZIP1) that facilitated cellular zinc uptake of high affinity (K(m)<0...
  76. ncbi Parathyroid hormone-related protein in lower vertebrates
    P M Ingleton
    Division of Genomic Medicine, Medical School, University of Sheffield, UK
    Comp Biochem Physiol B Biochem Mol Biol 132:87-95. 2002
    ..have been cloned in two teleost fishes, cDNA of sea bream (Sparus aurata) and genomic DNA of puffer fish (Fugu rubripes)...
  77. ncbi Expression and genomic organization of zonadhesin-like genes in three species of fish give insight into the evolutionary history of a mosaic protein
    Peter N D Hunt
    Centre for Biomedical Research, University of Victoria, Victoria, British Columbia V8W 3N5, Canada
    BMC Genomics 6:165. 2005
    ..Here we investigate the genomic structure and expression of zonadhesin-like genes in three species of fish...
  78. ncbi Genomic structure and sequence analysis of the valyl-tRNA synthetase gene of the Japanese pufferfish, Fugu rubripes
    E H Lim
    Department of Medicine, Addenbrookes Hospital, Cambridge, United Kingdom
    DNA Seq 7:141-51. 1997
    The genomic sequence and exon-intron organisation of the valyl-tRNA synthetase gene in the Japanese pufferfish, Fugu rubripes, have been determined. This single-copy Fugu gene spans 8.5 kb, about 2...
  79. ncbi Transcript expression profiles of Takifugu rubripes spermatozoa and eggs by expressed sequence tag analysis
    Xue Yan Shen
    Division of Life Science and Technology, Ocean University of China, Qingdao, 266003, PR China
    Fish Physiol Biochem 34:235-43. 2008
    Two cDNA libraries from Takifugu rubripes spermatozoa and eggs were constructed and a total of 620 expressed sequence tag (EST) clones were generated from the two libraries: 300 clones are from the spermatozoa library and 320 clones are ..
  80. ncbi Characterization and expression analysis of an interleukin-7 homologue in the Japanese pufferfish, Takifugu rubripes
    Tomoya Kono
    Department of Marine Biotechnology, Faculty of Agriculture, University of Miyazaki, Gakuenkibanadainishi 1 1, Miyazaki, Japan
    FEBS J 275:1213-26. 2008
    An interleukin-7 (IL-7) gene has been cloned and sequenced within the Japanese pufferfish, Takifugu rubripes (Fugu), providing the first conclusive evidence for the existence of IL-7 in teleosts...
  81. ncbi Genomic organization, transcript variants and comparative analysis of the human nucleoporin 155 (NUP155) gene
    Xiuqing Zhang
    Human Genome Center, Institute of Genetics, Chinese Academy of Sciences, Datun Road, Beijing 100101, China
    Gene 288:9-18. 2002
    ..and interpreted the genomic organization of the Nup155 orthologos from human (Homo sapiens) and pufferfish (Fugu rubripes), which are approximately 80 and 8 kb in length, respectively...
  82. ncbi Subfunctionalization of duplicate mitf genes associated with differential degeneration of alternative exons in fish
    Joachim Altschmied
    Department of Physiological Chemistry I, Biocenter Theodor Boveri Institute, University of Wurzburg, D 97074 Wurzburg, Germany
    Genetics 161:259-67. 2002
    ..however, are present in different teleost fish species including the poeciliid Xiphophorus, the pufferfishes Fugu rubripes and Tetraodon nigroviridis, and the zebrafish Danio rerio...
  83. ncbi Fish retroposons related to the Penelope element of Drosophila virilis define a new group of retrotransposable elements
    J N Volff
    Physiologische Chemie I, Biozentrum, University of Wurzburg, Germany
    Mol Genet Genomics 265:711-20. 2001
    ..identified in various teleost fish species, including the medakafish (Oryzias latipes), and the pufferfishes Fugu rubripes and Tetraodon nigroviridis, whose genomes are currently being sequenced...
  84. ncbi Conservation of a vitellogenin gene cluster in oviparous vertebrates and identification of its traces in the platypus genome
    Patrick J Babin
    Génomique et Physiologie des Poissons, Universite Bordeaux 1, UMR NuAGe, 33405 Talence, France
    Gene 413:76-82. 2008
    ..inverted genes were found in medaka (Oryzias latipes), stickleback (Gasterosteus aculeatus), pufferfish (Takifugu rubripes), and Tetrahodon (Tetraodon nigroviridis), while zebrafish (Danio rerio) Vtg3 may represent a residual trace ..
  85. ncbi Proliferation of kuchijirosho causative agent in a fugu-derived cell line
    E Hashimoto
    Research Center for Marine Bioresources, Faculty of Biotechnology, Fukui Prefectural University, Fukui, Japan
    J Fish Dis 31:443-9. 2008
    Kuchijirosho is a fatal disease of commercially cultured fugu, Takifugu rubripes. The transmissible nature of kuchijirosho strongly suggests that an infectious pathogen is the causative agent...
  86. ncbi Comparative genomics approach to the expression of figalpha, one of the earliest marker genes of oocyte differentiation in medaka (Oryzias latipes)
    Akira Kanamori
    Division of Biological Sciences, Graduate School of Science, Nagoya University, Chikusa, Nagoya 464 8602, Japan
    Gene 423:180-7. 2008
    ....
  87. ncbi Genomic, evolutionary, and expression analyses of cee, an ancient gene involved in normal growth and development
    Jorge M O Fernandes
    Department of Fisheries and Natural Sciences, Bodø University College, N 8049 Bodø, Norway
    Genomics 91:315-25. 2008
    ..These data, together with functional screens in yeast and Caenorhabditis elegans, indicate that cee has a hitherto uncharacterized role in normal growth and development...
  88. ncbi Identification and correction of abnormal, incomplete and mispredicted proteins in public databases
    Alinda Nagy
    Institute of Enzymology, Biological Research Center, Hungarian Academy of Sciences, H 1113 Budapest, Hungary
    BMC Bioinformatics 9:353. 2008
    ....
  89. ncbi Analyses of the extent of shared synteny and conserved gene orders between the genome of Fugu rubripes and human 20q
    Sarah F Smith
    Fugu Genomics, United Kingdom Human Genome Mapping Project Resource Centre, Wellcome Genome Campus, Hinxton Hall, Hinxton, Cambridgeshire, CB10 1SB, United Kingdom
    Genome Res 12:776-84. 2002
    ....
  90. ncbi Comparative analysis of the ETV6 gene in vertebrate genomes from pufferfish to human
    A Montpetit
    Division of Hematology Oncology, Charles Bruneau Cancer Center, Sainte Justine Hospital, Montreal, Quebec H3T 1C5, Canada
    Oncogene 20:3437-42. 2001
    ..In this study, we cloned and sequenced the homologue of ETV6 from the compact genome of the pufferfish Fugu rubripes (fETV6)...
  91. ncbi Characterization of three novel members of the zebrafish Pax2/5/8 family: dependency of Pax5 and Pax8 expression on the Pax2.1 (noi) function
    P L Pfeffer
    Research Institute of Molecular Pathology, Dr Bohr Gasse 7, A 1030 Vienna, Austria
    Development 125:3063-74. 1998
    ..Consequently, the noi mutation of zebrafish is equivalent to combined inactivation of the mouse Pax2 and Pax5 genes with regard to the loss of midbrain-hindbrain boundary development...
  92. ncbi Histopathological studies on Vibrio harveyi- infected tiger puffer, Takifugu rubripes (Temminck et Schlegel), cultured in Japan
    M M Mohi
    Graduate School of Bioresources, Mie University, Tsu, Mie, Japan
    J Fish Dis 33:833-40. 2010
    Vibrio harveyi infection occurred with a moderate mortality in tiger puffer, Takifugu rubripes (Temminck et Schlegel), in autumn 2007, at a mariculture farm in western Japan...
  93. ncbi Isolation and characterisation of the retinoic acid receptor-alpha gene in the Japanese pufferfish, F. rubripes
    J M Wentworth
    Department of Medicine, University of Cambridge, Level 5, Addenbrooke s Hospital, Cambridge CB2 2QQ, UK
    Gene 236:315-23. 1999
    ..NRs by cloning the retinoic acid receptor-alpha (RARalpha) gene from the genome of the Japanese pufferfish, Fugu rubripes. The fRARalpha gene is more compact than its human and murine counterparts and demonstrates a highly conserved ..
  94. ncbi Lymphocyte surface marker genes in fugu
    Hiroaki Suetake
    Fisheries Laboratory, The University of Tokyo, Maisaka, Hamamatsu, Shizuoka 431 0214, Japan
    Comp Biochem Physiol Part D Genomics Proteomics 1:102-8. 2006
    ..g. antibodies) to identify immune cells. The genomic sequence of Takifugu rubripes (fugu) represents an important resource to facilitate the identification of lymphocyte-related genes...
  95. ncbi Purification and characterization of tributyltin-binding protein of tiger puffer, Takifugu rubripes
    Yumi Oba
    Laboratory of Marine Environmental Science, Faculty of Agriculture, Kyushu University, Hakozaki 6 10 1, Higashi ku, Fukuoka, 812 8581, Japan
    Comp Biochem Physiol C Toxicol Pharmacol 153:17-23. 2011
    We successfully purified Trub.TBT-bp?, a tributyltin (TBT) binding protein (bp) of the tiger puffer, Takifugu rubripes. Tiger puffer was injected intraperitoneally with TBT (1.0mg/kg body weight) and Trub...
  96. ncbi Characterization of the two zebrafish orthologues of the KAL-1 gene underlying X chromosome-linked Kallmann syndrome
    O Ardouin
    Unité de Génétique des Déficits Sensoriels, CNRS URA 1968, Institut Pasteur, 25 rue du Dr Roux, F 75724, Paris, France
    Mech Dev 90:89-94. 2000
    ..The relevance of the zebrafish as an animal model for studying both the function of KAL-1 in normal development and the developmental failure leading to the olfactory defect in Kallmann syndrome, is discussed...
  97. ncbi CRTAC1 homolog proteins are conserved from cyanobacteria to man and secreted by the teleost fish pituitary gland
    Begona Redruello
    Centre of Marine Sciences, University of Algarve, Gambelas, Faro, Portugal
    Gene 456:1-14. 2010
    ..This will be essential to elucidate their respective biological roles...
  98. ncbi Relaxin gene family in teleosts: phylogeny, syntenic mapping, selective constraint, and expression analysis
    Sara V Good-Avila
    Department of Biology, University of Winnipeg, Winnipeg, Manitoba, R3E 2H9, Canada
    BMC Evol Biol 9:293. 2009
    ..rerio testis...
  99. ncbi Two interleukin (IL)-15 homologues in fish from two distinct origins
    Jin Xin Bei
    Institute of Aquatic Economic Animals, Sun Yat Sen Zhongshan University, Guangzhou 510275, China
    Mol Immunol 43:860-9. 2006
    ..The two genes, isolated from fugu (Takifugu rubripes), resemble to mammalian IL-15 but differ from IL-2 and IL-21 in their amino acid sequences, the possessing ..
  100. ncbi Short Promoters in Viral Vectors Drive Selective Expression in Mammalian Inhibitory Neurons, but do not Restrict Activity to Specific Inhibitory Cell-Types
    Jason L Nathanson
    Systems Neurobiology Laboratories, Salk Institute for Biological Studies La Jolla, CA, USA
    Front Neural Circuits 3:19. 2009
    ..We tested many gene regulatory sequences derived from fugu (Takifugu rubripes), mouse, human, and synthetic composite regulatory elements...
  101. ncbi Plasma protein binding of tetrodotoxin in the marine puffer fish Takifugu rubripes
    Takuya Matsumoto
    Department of Food Science and Technology, Tokyo University of Marine Science and Technology, Konan 4 5 7, Minato, Tokyo 108 8477, Japan
    Toxicon 55:415-20. 2010
    ..fish, we used equilibrium dialysis to measure protein binding of TTX in the plasma of the marine puffer fish Takifugu rubripes and the non-toxic greenling Hexagrammos otakii, and in solutions of bovine serum albumin (BSA) and bovine ..

Research Grants52

  1. MOLECULAR ANALYSIS IN ALAGILLE SYNDROME
    Ian Krantz; Fiscal Year: 2002
    ..sequences that will be focused on in this proposal include cDNA selection and use of the puffer fish (Fugu rubripes) syntenic region to identify conserved sequences...
  2. Fugu Promoters for Mammalian Cortical Neurons
    EDWARD CALLAWAY; Fiscal Year: 2006
    ..This proposal aims to identify short promoter sequences from the genome of Fugu rubripes ("Fugu") which can be used to selectively drive gene expression in specific types of mammalian cortical ..
  3. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin Hughes; Fiscal Year: 2007
    ..In addition, by increasing our understanding of the population diversity and evolutionary history of human immune system genes, this research will enhance our knowledge of human immune function in health and disease. ..
  4. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin Hughes; Fiscal Year: 2009
    ..In addition, by increasing our understanding of the population diversity and evolutionary history of human immune system genes, this research will enhance our knowledge of human immune function in health and disease. ..
  5. AHR signaling in Mammalian and Non-Mammalian Models
    Mark E Hahn; Fiscal Year: 2011
    ....
  6. Generation of an In Vivo Human Genome Enhancer Dataset
    LEN ALEXANDER PENNACCHIO; Fiscal Year: 2010
    ..The identification of positive signatures of enhancers in vivo is expected to significantly fill our void in gene regulatory annotation of the human genome and to decipher their mutation as a cause of human disease. ..
  7. Generation of an In Vivo Human Genome Transcriptional Enhancer Dataset
    Len Pennacchio; Fiscal Year: 2009
    ..Such a community resource is expected to significantly fill our void in gene regulatory annotation of the human genome and to decipher their mutation as a cause of human disease. . ..
  8. A High-Resolution Enhancer Atlas of the Developing Forebrain
    LEN ALEXANDER PENNACCHIO; Fiscal Year: 2010
    ..These studies are likely to have implications in defining the role of these switches for normal brain function and how they go awry in human brain diseases. ..
  9. Mechanisms of Embryo Response to Oxidative Stress
    Mark E Hahn; Fiscal Year: 2010
    ....
  10. Gene Delivery in Retinal Diseases
    John M Nickerson; Fiscal Year: 2010
    ..The second goal is to evaluate the safety and efficacy of RPE65 gene delivery and expression in vivo in mice with lesions in this gene. ..
  11. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin L Hughes; Fiscal Year: 2010
    ..In addition, by increasing our understanding of the population diversity and evolutionary history of human immune system genes, this research will enhance our knowledge of human immune function in health and disease. ..
  12. AHR signaling in Mammalian and Non-Mammalian Models
    Mark E Hahn; Fiscal Year: 2010
    ....
  13. Generation of an In Vivo Human Genome Transcriptional Enhancer Dataset
    Len Pennacchio; Fiscal Year: 2009
    ..Such a community resource is expected to significantly fill our void in gene regulatory annotation of the human genome and to decipher their mutation as a cause of human disease. . ..
  14. AHR signaling in Mammalian and Non-Mammalian Models
    MARK HAHN; Fiscal Year: 2007
    ..Multiple AHRs from medaka (Oryzias latipes) and pufferfish (Fugu rubripes) will be characterized in vitro and expressed in AHR-deficient mouse cells ¿ TCDD to determine whether ..
  15. Gene Delivery in Retinal Diseases
    JOHN NICKERSON; Fiscal Year: 2007
    ..The second goal is to evaluate the safety and efficacy of RPE65 gene delivery and expression in vivo in mice with lesions in this gene. ..
  16. Aryl hydrocarbon receptor regulation of the cell cycle by chromatin modification
    REBEKA MERSON; Fiscal Year: 2007
    ..Furthermore, the results will provide the basic research for developing therapeutic interventions to chemical-induced tumors and may predict cell cycle stages susceptible to cancer. ..
  17. Genoplasty in Ocular Gene Therapy
    JOHN NICKERSON; Fiscal Year: 2004
    ..abstract_text> ..
  18. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin Hughes; Fiscal Year: 2002
    ....
  19. AH RECEPTOR IN NON-MAMMALIAN MODELS
    MARK HAHN; Fiscal Year: 2001
    ..We will determine the diversity and function of AHR genes in fish species commonly used as aquatic models, test the hypothesis that a second AHR-like gene exists in humans, and compare the function of fish and human AHRs. ..
  20. Gene Duplication and Genome Evolution
    Austin Hughes; Fiscal Year: 2004
    ..5) Examining the role of transposable elements in duplication of genomic segments by testing for nonrandom association between these elements and putatively duplicated blocks in the yeast genome. ..
  21. EVOLUTION OF IMMUNE RECOGNITION AND EVASION
    Austin Hughes; Fiscal Year: 2006
    ..abstract_text> ..
  22. Genetic and Genomic Analysis of apoAV
    Len Pennacchio; Fiscal Year: 2006
    ..abstract_text> ..