tiger puffer

Summary

Alias: torafugu, Takifugu rubripes, Fugu rubripes, Sphaeroides rubripes, Takifugu rubripes (Temminck & Schlegel, 1850), Tetraodon rubripes

Top Publications

  1. Brunner B, Gr tzner F, Yaspo M, Ropers H, Haaf T, Kalscheuer V. Molecular cloning and characterization of the Fugu rubripes MEST/COPG2 imprinting cluster and chromosomal localization in Fugu and Tetraodon nigroviridis. Chromosome Res. 2000;8:465-76 pubmed
    ..Comparative mapping of these genes by fluorescence in-situ hybridization to metaphase chromosomes of Fugu rubripes and Tetraodon nigroviridis showed clear signals on one of the smallest acrocentric chromosomal pairs, which in ..
  2. Zimek A, Stick R, Weber K. Genes coding for intermediate filament proteins: common features and unexpected differences in the genomes of humans and the teleost fish Fugu rubripes. J Cell Sci. 2003;116:2295-302 pubmed publisher
    We screened the genomic sequences of the teleost fish Fugu rubripes for genes that encode cytoplasmic intermediate filament (IF) proteins...
  3. Ng C, Osato M, Tay B, Venkatesh B, Ito Y. cDNA cloning of Runx family genes from the pufferfish (Fugu rubripes). Gene. 2007;399:162-73 pubmed publisher
    ..Here we report the cDNA cloning of the full Runx gene family of the pufferfish (Fugu rubripes), which comprises frRunx1, frRunx2, frRunx3, frRunt and frCbfb...
  4. Kato A, Muro T, Kimura Y, Li S, Islam Z, Ogoshi M, et al. Differential expression of Na+-Cl- cotransporter and Na+-K+-Cl- cotransporter 2 in the distal nephrons of euryhaline and seawater pufferfishes. Am J Physiol Regul Integr Comp Physiol. 2011;300:R284-97 pubmed publisher
    ..On the other hand, the kidney of seawater pufferfish (torafugu, Takifugu rubripes), which lacked distal tubules, expressed very low levels of NCC, and, in the collecting ducts, high levels ..
  5. Aparicio S, Hawker K, Cottage A, Mikawa Y, Zuo L, Venkatesh B, et al. Organization of the Fugu rubripes Hox clusters: evidence for continuing evolution of vertebrate Hox complexes. Nat Genet. 1997;16:79-83 pubmed publisher
    ..We have studied the Hox gene clusters of a teleost fish, Fugu rubripes, to test the possibility that Hox organization may have varied since the origin of jawed vertebrates...
  6. Yeo G, Elgar G, Sandford R, Brenner S. Cloning and sequencing of complement component C9 and its linkage to DOC-2 in the pufferfish Fugu rubripes. Gene. 1997;200:203-11 pubmed
    The Japanese pufferfish Fugu rubripes has a 400 Mb genome with high gene density and minimal non-coding complexity, and is therefore an ideal vertebrate model for sequence comparison...
  7. Armes N, Gilley J, Fried M. The comparative genomic structure and sequence of the surfeit gene homologs in the puffer fish Fugu rubripes and their association with CpG-rich islands. Genome Res. 1997;7:1138-52 pubmed
    The puffer fish Fugu rubripes (Fugu) has a compact genome approximately one-seventh the size of man, mainly owing to small intron size and the presence of few dispersed repetitive DNA elements, which greatly facilitates the study of its ..
  8. Bolland D, Hewitt J. Intron loss in the SART1 genes of Fugu rubripes and Tetraodon nigroviridis. Gene. 2001;271:43-9 pubmed
    ..examined the genomic structure and cDNA sequence of the SART1 gene in the compact genomes of the pufferfish Fugu rubripes and Tetraodon nigroviridis...
  9. Bagheri Fam S, Ferraz C, Demaille J, Scherer G, Pfeifer D. Comparative genomics of the SOX9 region in human and Fugu rubripes: conservation of short regulatory sequence elements within large intergenic regions. Genomics. 2001;78:73-82 pubmed publisher
    ..7 Mb and 195 kb of sequence around human and Fugu rubripes SOX9, respectively. We identified only seven and five protein-coding genes in the human and F...

More Information

Publications211 found, 100 shown here

  1. Eggers J, Stock M, Fliegauf M, Vonderstrass B, Otto F. Genomic characterization of the RUNX2 gene of Fugu rubripes. Gene. 2002;291:159-67 pubmed
    A 105 kb Fugu rubripes genomic region containing the RUNX2 ortholog (frunx2) was sequenced and analysed. Spanning 32 kb, frunx2 is seven times smaller than its human orthologue (223 kb)...
  2. Elmerot C, Arnason U, Gojobori T, Janke A. The mitochondrial genome of the pufferfish, Fugu rubripes, and ordinal teleostean relationships. Gene. 2002;295:163-72 pubmed
    The small nuclear genome of the pufferfish, Fugu rubripes (order Tetraodontiformes), makes this species highly interesting for genome research...
  3. Oidtmann B, Simon D, Holtkamp N, Hoffmann R, Baier M. Identification of cDNAs from Japanese pufferfish (Fugu rubripes) and Atlantic salmon (Salmo salar) coding for homologues to tetrapod prion proteins. FEBS Lett. 2003;538:96-100 pubmed
    ..for homologues to tetrapod prion proteins (PrPs) in Atlantic salmon (Salmo salar) and Japanese pufferfish (Fugu rubripes), which were termed 'similar to PrPs' (stPrPs)...
  4. Koopman P, Schepers G, Brenner S, Venkatesh B. Origin and diversity of the SOX transcription factor gene family: genome-wide analysis in Fugu rubripes. Gene. 2004;328:177-86 pubmed publisher
    ..We have now analysed the Sox gene complement in the pufferfish, Fugu rubripes, in order to shed further light on the diversity and origins of the Sox gene family...
  5. Cardoso J, Power D, Elgar G, Clark M. Duplicated receptors for VIP and PACAP (VPAC1R and PAC1R) in a teleost fish, Fugu rubripes. J Mol Endocrinol. 2004;33:411-28 pubmed publisher
    ..with human PAC1R and VPAC1R and were identified and characterised at the genomic level in the teleost fish Fugu rubripes. An additional group orthologous with VPAC2R was also identified and partially characterised...
  6. Bird S, Zou J, Kono T, Sakai M, Dijkstra J, Secombes C. Characterisation and expression analysis of interleukin 2 (IL-2) and IL-21 homologues in the Japanese pufferfish, Fugu rubripes, following their discovery by synteny. Immunogenetics. 2005;56:909-23 pubmed publisher
    ..The IL-2 and IL-21 sequences have been determined in Fugu rubripes by exploiting the conservation of synteny that is found between regions of the human and Fugu genomes...
  7. Bird S, Zou J, Savan R, Kono T, Sakai M, Woo J, et al. Characterisation and expression analysis of an interleukin 6 homologue in the Japanese pufferfish, Fugu rubripes. Dev Comp Immunol. 2005;29:775-89 pubmed publisher
    The first IL-6 sequence in fish has been determined in Fugu rubripes by exploiting the synteny that is found between some regions of the human and Fugu genomes...
  8. Ebert A, McAnelly C, Srinivasan A, Linker J, Horne W, Garrity D. Ca2+ channel-independent requirement for MAGUK family CACNB4 genes in initiation of zebrafish epiboly. Proc Natl Acad Sci U S A. 2008;105:198-203 pubmed publisher
    ..This study defines a YSL-driven zygotic mechanism essential for epiboly initiation and reveals a Ca(2+) channel-independent beta4 protein function potentially involving the cytoskeleton...
  9. Park J, Semyonov J, Chang C, Yi W, Warren W, Hsu S. Origin of INSL3-mediated testicular descent in therian mammals. Genome Res. 2008;18:974-85 pubmed publisher
  10. Trower M, Orton S, Purvis I, Sanseau P, Riley J, Christodoulou C, et al. Conservation of synteny between the genome of the pufferfish (Fugu rubripes) and the region on human chromosome 14 (14q24.3) associated with familial Alzheimer disease (AD3 locus). Proc Natl Acad Sci U S A. 1996;93:1366-9 pubmed
    The genome of the pufferfish (Fugu rubripes) (400 Mb) is approximately 7.5 times smaller than the human genome, but it has a similar gene repertoire to that of man. If regions of the two genomes exhibited conservation of gene order (i.e...
  11. Tim n M, Elgar G, Habu S, Okumura K, Beverley P. Molecular cloning of major histocompatibility complex class I cDNAs from the pufferfish Fugu rubripes. Immunogenetics. 1998;47:170-3 pubmed
  12. Auf der Maur A, Belser T, Elgar G, Georgiev O, Schaffner W. Characterization of the transcription factor MTF-1 from the Japanese pufferfish (Fugu rubripes) reveals evolutionary conservation of heavy metal stress response. Biol Chem. 1999;380:175-85 pubmed publisher
    The pufferfish Fugu rubripes was recently introduced as a new model organism for genomic studies, since it contains a full set of vertebrate genes but only 13% as much DNA as a mammal...
  13. Suzuki T, Kurokawa T, Hashimoto H, Sugiyama M. cDNA sequence and tissue expression of Fugu rubripes prion protein-like: a candidate for the teleost orthologue of tetrapod PrPs. Biochem Biophys Res Commun. 2002;294:912-7 pubmed publisher
    We report the isolation and characterization of a cDNA coding for Fugu rubripes prion protein (PrP)-like of 180 amino acids which includes the PrP-conserved hydrophobic region homologous to that of Xenopus PrP...
  14. Tsutsui S, Tasumi S, Suetake H, Suzuki Y. Lectins homologous to those of monocotyledonous plants in the skin mucus and intestine of pufferfish, Fugu rubripes. J Biol Chem. 2003;278:20882-9 pubmed publisher
    We have characterized pufflectin, a novel mannose-specific lectin, from the skin mucus of the pufferfish, Fugu rubripes. Molecular mass estimations by gel filtration and matrix-assisted laser desorption ionization time-of-flight mass ..
  15. Zou J, Clark M, Secombes C. Characterisation, expression and promoter analysis of an interleukin 10 homologue in the puffer fish, Fugu rubripes. Immunogenetics. 2003;55:325-35 pubmed publisher
    Using computer-based tools, an interleukin (IL) 10 homologue has been identified from the puffer fish ( Fugu rubripes) genome database. This is the first report on the existence of an IL-10 homologue in a non-mammalian vertebrate species...
  16. Sambrook J, Campbell R, Elgar G. Characterisation of a gene cluster in Fugu rubripes containing the complement component C4 gene. Gene. 2003;312:73-83 pubmed
    In this study, we describe the characterisation of the complement component C4 gene in Fugu rubripes. The Fugu C4 gene, orthologous to the tetrapod C4 gene, encompasses a genomic span of 9702 base pairs and contains 41 exons, encoding ..
  17. Guselnikov S, Najakshin A, Taranin A. Fugu rubripes possesses genes for the entire set of the ITAM-bearing transmembrane signal subunits. Immunogenetics. 2003;55:472-9 pubmed publisher
    ..We surveyed the genomic sequences of the teleostean fish Fugu rubripes for the presence of genes encoding these accessory molecules...
  18. Myslinski E, Krol A, Carbon P. Characterization of snRNA and snRNA-type genes in the pufferfish Fugu rubripes. Gene. 2004;330:149-58 pubmed publisher
    ..work, database search identified 35 snRNA and snRNA-type genes in the genome sequence of the pufferfish Fugu rubripes. Sequence comparisons of promoter elements, determination of template activities by microinjection into ..
  19. Qiu A, Hogstrand C. Functional characterisation and genomic analysis of an epithelial calcium channel (ECaC) from pufferfish, Fugu rubripes. Gene. 2004;342:113-23 pubmed publisher
    ..mammalian epithelial calcium channels, ECaC1 (TRPV5) and ECaC2 (TRPV6), was cloned from gill of pufferfish (Fugu rubripes) and characterised, demonstrating that this gene predates the evolution of land-living vertebrates. The F...
  20. Nakada T, Westhoff C, Kato A, Hirose S. Ammonia secretion from fish gill depends on a set of Rh glycoproteins. FASEB J. 2007;21:1067-74 pubmed
    ..We identified the Rh glycoprotein homologs, fRhag, fRhbg, fRhcg1, and fRhcg2, of the pufferfish, Takifugu rubripes. Northern blot, in situ hybridization, and immunohistochemistry revealed that the pufferfish erythroid Rh ..
  21. Tasumi S, Norshida I, Boxshall G, Kikuchi K, Suzuki Y, Ohtsuka S. Screening of candidate genes encoding proteins expressed in pectoral fins of fugu Takifugu rubripes, in relation to habitat site of parasitic copepod Caligus fugu, using suppression subtractive hybridization. Fish Shellfish Immunol. 2015;44:356-64 pubmed publisher
    ..fugu is a parasitic copepod specific to the tetraodontid genus Takifugu including the commercially important Takifugu rubripes. Despite the rapid accumulation of knowledge on other aspects of its biology, the host and settlement-site ..
  22. Akolkar D, Asaduzzaman M, Kinoshita S, Asakawa S, Watabe S. Characterization of Pax3 and Pax7 genes and their expression patterns during different development and growth stages of Japanese pufferfish Takifugu rubripes. Gene. 2016;575:21-8 pubmed publisher
    ..However, information regarding them in vertebrate genome model, torafugu Takifugu rubripes, has remained unknown...
  23. Pratheepa V, Vasconcelos V. Binding and Pharmacokinetics of the Sodium Channel Blocking Toxins (Saxitoxin and the Tetrodotoxins). Mini Rev Med Chem. 2016;: pubmed
    ..The pharmacokinetic studies (absorption, distribution and accumulation) reported on Takifugu rubripes, Takifugu pardalis, Takifugu niphobles, Takifugu vermicularis, Takifugu snyderi, etc...
  24. Bathige S, Umasuthan N, Godahewa G, Jayasinghe J, Whang I, Noh J, et al. A homolog of Kunitz-type serine protease inhibitor from rock bream, Oplegnathus fasciatus: Molecular insights and transcriptional modulation in response to microbial and PAMP stimulation, and tissue injury. Fish Shellfish Immunol. 2015;46:285-91 pubmed publisher
    ..Homology analysis revealed that RbKSPI shared the highest identity with the Kunitz homolog in Takifugu rubripes (77.6%). Phylogenetic analysis indicated that RbKSPI clusters with other teleostean KSPIs...
  25. Guo C, Cui H, Ni S, Yan Y, Qin Q. Comprehensive identification and profiling of host miRNAs in response to Singapore grouper iridovirus (SGIV) infection in grouper (Epinephelus coioides). Dev Comp Immunol. 2015;52:226-35 pubmed publisher
    ..these miRNAs shared high sequence similarity with miRNAs identified in zebrafish (Danio rerio), pufferfish (Fugu rubripes), and other higher vertebrates...
  26. Yan H, Shen X, Cui X, Wu Y, Wang L, Zhang L, et al. Identification of genes involved in gonadal sex differentiation and the dimorphic expression pattern in Takifugu rubripes gonad at the early stage of sex differentiation. Fish Physiol Biochem. 2018;44:1275-1290 pubmed publisher
    ..This is the first report of gonadal transcriptome of fugu at early sex differentiation stage, and our results provide an archive for further study on molecular mechanism underlying sex differentiation in this species. ..
  27. Xu H, Zhang Q, Wei Y, Liao Z, Liang M. Dietary methionine increased the lipid accumulation in juvenile tiger puffer Takifugu rubripes. Comp Biochem Physiol B Biochem Mol Biol. 2019;230:19-28 pubmed publisher
    ..study was aimed at investigating the effects of dietary Met supplementation on the lipid accumulation in tiger puffer, which have a unique lipid storage pattern...
  28. Yoshitake K, Igarashi Y, Mizukoshi M, Kinoshita S, Mitsuyama S, Suzuki Y, et al. Artificially designed hybrids facilitate efficient generation of high-resolution linkage maps. Sci Rep. 2018;8:16104 pubmed publisher
    ..Using SELDLA, linkage maps and improved genomes for two species of pufferfish, Takifugu rubripes and Takifugu stictonotus, were obtained simultaneously...
  29. Zhang H, Fu Y, Su Y, Shi Z, Zhang J. Identification and expression of HDAC4 targeted by miR-1 and miR-133a during early development in Paralichthys olivaceus. Comp Biochem Physiol B Biochem Mol Biol. 2015;179:1-8 pubmed publisher
    ..The phylogenetic analysis indicated that Paralichthys olivaceus HDAC4 had the highest identity with the Takifugu rubripes. Tissue distribution analysis indicated that HDAC4 is abundantly expressed in muscle, and its levels are ..
  30. Kiriake A, Ohta A, Suga E, Matsumoto T, Ishizaki S, Nagashima Y. Comparison of tetrodotoxin uptake and gene expression in the liver between juvenile and adult tiger pufferfish, Takifugu rubripes. Toxicon. 2016;111:6-12 pubmed publisher
    ..The profile of TTX accumulation is reported to differ between tiger pufferfish Takifugu rubripes juveniles and adults administered TTX...
  31. Pan J, Li Q, Jia H, Xia L, Jin W, Shang M, et al. Physiochemical and functional properties of tiger puffer (Takifugu rubripes) skin gelatin as affected by extraction conditions. Int J Biol Macromol. 2018;109:1045-1053 pubmed publisher
    The study investigated physiochemical and functional properties of gelatins from tiger puffer skin (GTPS) extracted with warm-water method at 45, 55 and 65°C for 3, 6 and 12h...
  32. Liu X, Jiao C, Ma Y, Wang Q, Zhang Y. A live attenuated Vibrio anguillarum vaccine induces efficient immunoprotection in Tiger puffer (Takifugu rubripes). Vaccine. 2018;36:1460-1466 pubmed publisher
    Tiger puffer (Takifugu rubripes) is becoming an economic promising aquaculture species in China. However, the development of Tiger puffer breeding industry is restricted by some serious aquatic disease such as vibriosis...
  33. Pan J, Jia H, Shang M, Li Q, Xu C, Wang Y, et al. Effects of deodorization by powdered activated carbon, β-cyclodextrin and yeast on odor and functional properties of tiger puffer (Takifugu rubripes) skin gelatin. Int J Biol Macromol. 2018;118:116-123 pubmed publisher
    The study investigated odor, physiochemical and functional properties of tiger puffer skin gelatin (TPSG) deodorized by powdered activated carbon (PAC, 0.5%), β-cyclodextrin (βCD, 3%) and yeast fermentation (YEF, 1%)...
  34. Kim J, Lee J, Bae J, An C, Nam B, Jeong J, et al. First molecular characterisation and expression analysis of a teleost thioredoxin-interacting protein (TXNIP) gene from rock bream (Oplegnathus fasciatus). Dev Comp Immunol. 2015;52:69-74 pubmed publisher
    ..Phylogenetic analysis indicated that RbTXNIP is most closely related to Fugu rubripes TXNIP. RbTXNIP was expressed significantly in the RBC, intestine, and spleen...
  35. Mo Z, Wang J, Yang M, Ni L, Wang H, Lao G, et al. Characterization and expression analysis of grouper (Epinephelus coioides) co-stimulatory molecules CD83 and CD80/86 post Cryptocaryon irritans infection. Fish Shellfish Immunol. 2017;67:467-474 pubmed publisher
    ..EcCD80/86 shares the highest amino acid similarity (51% and 47%) for the overall sequence with puffer fish (Takifugu rubripes)...
  36. Buemi M, Lacquaniti A, Maricchiolo G, Bolignano D, Campo S, Cernaro V, et al. Regenerative medicine: does Erythropoietin have a role?. Curr Pharm Des. 2009;15:2026-36 pubmed
    ..Furthermore, the demonstration of a cardiac production of EPO in Fugu rubripes and in Zebrafish has led cardiologists to "discover" Erythropoietin, postulating a hypothetical role in ..
  37. Tanaka R, Shigeta K, Sugiura Y, Hatate H, Matsushita T. Accumulation of hydroxyl lipids and 4-hydroxy-2-hexenal in live fish infected with fish diseases. Lipids. 2014;49:385-96 pubmed publisher
    ..In the liver of puffer fish (Fugu rubripes) infected with Trichodina, L-OH and HHE levels significantly increased from 25.29±5.04 to 47.70 ± 5...
  38. Sumi K, Nou I, Kho K. Identification and expression of a novel carbonic anhydrase isozyme in the pufferfish Takifugu vermicularis. Gene. 2016;588:173-9 pubmed publisher
    ..Based on the high homology of two predicted CA sequences of the tiger puffer (Takifugu rubripes), a 1715bp novel cDNA was obtained from T. vermicularis...
  39. Zhang X, Mizukoshi M, Zhang H, Tan E, Igarashi Y, Suzuki Y, et al. Ultrahigh-Density Linkage Map Construction Using Low-Coverage Whole-Genome Sequencing of a Doubled Haploid Population: Case Study of Torafugu (Takifugu rubripes). Genes (Basel). 2018;9: pubmed publisher
    ..Here, using torafugu (Takifugu rubripes) as a test model, we propose a new strategy for ultrahigh-density genetic linkage map construction using ..
  40. Fang D, Zhao C, Jiang S, Zhou Y, Xu D. Toxic function of CD28 involving in the TLR/MyD88 signal pathway in the river pufferfish (Takifugu obscurus) after exposed to tributyltin chloride (TBT-Cl). Gene. 2019;688:84-92 pubmed publisher
    ..The phylogenetic analysis showed that To-CD28 is similar to the CD28 protein in Takifugu rubripes. The total hematocyte count distinctly decreased after TBT-Cl exposure, showing the adverse effects of TBT-..
  41. Honda M, Muta A, Shimazaki A, Akasaka T, Yoshikuni M, Shimasaki Y, et al. High concentrations of perfluorooctane sulfonate in mucus of tiger puffer fish Takifugu rubripes: a laboratory exposure study. Environ Sci Pollut Res Int. 2018;25:1551-1558 pubmed publisher
    ..was investigated in tissues (plasma, blood clot, mucus, skin, liver, muscle, and gonad) of tiger puffer fish Takifugu rubripes. A single dose of PFOS was intraperitoneally injected at 0...
  42. Tsutsui S, Suzuki Y, Shibuya K, Nakamura O. Sacciform cells in the epidermis of fugu (Takifugu rubripes) produce and secrete kalliklectin, a novel lectin found in teleosts. Fish Shellfish Immunol. 2018;80:311-318 pubmed publisher
    Kalliklectin is a novel lectin identified in the skin mucus and blood plasma of teleosts, including fugu (Takifugu rubripes). It has been found to exhibit sequence similarity to mammalian plasma kallikrein and coagulation factor XI...
  43. Biswas G, Nagamine R, Hikima J, Sakai M, Kono T. Inductive immune responses in the Japanese pufferfish (Takifugu rubripes) treated with recombinant IFN-γ, IFN-γrel, IL-4/13A and IL-4/13B. Int Immunopharmacol. 2016;31:50-6 pubmed publisher
    ..Therefore, we synthesized and purified the Japanese pufferfish, (Takifugu rubripes) recombinant cytokines, namely interferon-gamma (IFN-γ), IFN-γrel, interleukin (IL)-4/13A and IL-4/13B,..
  44. Xu D, Jiang S, Zhao C, Fang D, Hu H. Comparative transcriptomics analysis of the river pufferfish (Takifugu obscurus) by tributyltin exposure: Clues for revealing its toxic injury mechanism. Fish Shellfish Immunol. 2018;82:536-543 pubmed publisher
    ..obscurus when exposed to TBT. The obtained data were compared with the genome data of Takifugu rubripes and transcriptional resource database...
  45. Kaneko T, Freeha K, Wu X, Mogi M, Uji S, Yokoi H, et al. Role of notochord cells and sclerotome-derived cells in vertebral column development in fugu, Takifugu rubripes: histological and gene expression analyses. Cell Tissue Res. 2016;366:37-49 pubmed publisher
    ..We therefore examined the histology and gene expression profile of vertebral development in fugu, Takifugu rubripes, a model organism for genomic research...
  46. Ahn H, Lee C, Nam B, Kim E, Caetano Anolles K, Kim H. Selective pressure on the protein-coding genes of the pufferfish is correlated with phenotypic traits. Mar Genomics. 2018;37:182-186 pubmed publisher
    ..We downloaded well-annotated gene information of two pufferfish species, Takifugu rubripes and Tetraodon nigroviridis, from the public ENSEMBL database...
  47. Tatsuno R, Gao W, Ibi K, Mine T, Okita K, Nishihara G, et al. Profile differences in tetrodotoxin transfer to skin and liver in the pufferfish Takifugu rubripes. Toxicon. 2017;130:73-78 pubmed publisher
    Tetrodotoxin (TTX) was intramuscularly administered to nontoxic cultured specimens of the pufferfish Takifugu rubripes to investigate differences in the toxin transfer and accumulation profiles between the skin and liver...
  48. Mao K, Chen W, Mu Y, Ao J, Chen X. Identification of two IL-4/13 homologues in large yellow croaker (Larimichthys crocea) revealed their similar roles in inducing alternative activation of monocytes/macrophages. Fish Shellfish Immunol. 2018;80:180-190 pubmed publisher
    ..showed that LcIL-4/13A is evolutionarily closely related to Dicentrarchus labrax IL-4/13A, and LcIL-4/13B to Takifugu rubripes IL-4/13B...
  49. Zhu C, Tong J, Yu X, Guo W. Comparative mapping for bighead carp (Aristichthys nobilis) against model and non-model fishes provides insights into the genomic evolution of cyprinids. Mol Genet Genomics. 2015;290:1313-26 pubmed publisher
    ..7 %), Tetraodon nigroviridis (6.4 %), Gasterosteus aculeatus (5.2 %), Oryzias latipes (4.7 %) and Fugu rubripes (3.5 %)...
  50. Gao K, Wang Z, Zhou X, Wang H, Kong D, Jiang C, et al. Comparative transcriptome analysis of fast twitch muscle and slow twitch muscle in Takifugu rubripes. Comp Biochem Physiol Part D Genomics Proteomics. 2017;24:79-88 pubmed publisher
    Fast twitch muscle and slow twitch muscle are two important organs of Takifugu rubripes. Both tissues are of ectodermic origin, and the differences between the two muscle fibers reflect the differences in their myofibril protein ..
  51. Hosoya S, Suetake H, Suzuki Y, Kikuchi K. Genetic Basis Underlying Behavioral Correlation Between Fugu Takifugu rubripes and a Closely Related Species, Takifugu niphobles. Behav Genet. 2015;45:560-72 pubmed publisher
    ..swimming, reaction to a novel object and activity in a novel environment) between two pufferfish species, Takifugu rubripes and T. niphobles...
  52. Li Z, Li Y, Xu S, Xu Y, Mo Z, Dan X, et al. Grouper (Epinephelus coioides) TCR signaling pathway was involved in response against Cryptocaryon irritans infection. Fish Shellfish Immunol. 2017;64:176-184 pubmed publisher
    ..Homology analysis showed that they all shared the highest identity with corresponding genes from Takifugu rubripes (EcCD3? 41%, EcLck 88%, EcFyn 98% and EcZAP70 93%), and their conserved motifs involved in the signaling ..
  53. A A, Nadimpalli S. Takifugu rubripes cation independent mannose 6-phosphate receptor: Cloning, expression and functional characterization of the IGF-II binding domain. Int J Biol Macromol. 2018;113:59-65 pubmed publisher
    ..Preliminary analysis suggests that the binding mechanism as well as the affinity of the fish and human receptor for IGF-II may have varied according to different evolutionary pressures. ..
  54. Inoue Y, Suenaga Y, Yoshiura Y, Moritomo T, Ototake M, Nakanishi T. Molecular cloning and sequencing of Japanese pufferfish (Takifugu rubripes) NADPH oxidase cDNAs. Dev Comp Immunol. 2004;28:911-25 pubmed publisher
    ..These results suggest that Japanese pufferfish NADPH oxidase components possess functional activities similar to those of human...
  55. Yoshiura Y, Kiryu I, Fujiwara A, Suetake H, Suzuki Y, Nakanishi T, et al. Identification and characterization of Fugu orthologues of mammalian interleukin-12 subunits. Immunogenetics. 2003;55:296-306 pubmed publisher
    We have isolated and characterized cDNAs and genes for pufferfish, Fugu rubripes, (Fugu) orthologues of mammalian interleukin (IL)-12 subunits (IL-12 p35 and IL-12 p40)...
  56. Savan R, Aman A, Sato K, Yamaguchi R, Sakai M. Discovery of a new class of immunoglobulin heavy chain from fugu. Eur J Immunol. 2005;35:3320-31 pubmed publisher
    ..The expression pattern of the gene has been confirmed by in situ hybridization and PCR studies...
  57. Zhang D, Han F, Yu D, Xiao S, Li M, Chen J, et al. Characterization of E3 ubiquitin ligase neuregulin receptor degradation protein-1 (Nrdp1) in the large yellow croaker (Larimichthys crocea) and its immune responses to Cryptocaryon irritans. Gene. 2015;556:98-105 pubmed publisher
    ..In fishes, Nrdp1 in large yellow croaker was closer with that in Takifugu rubripes. The expression profile showed that LcNrdp1 was constitutively expressed in all tested tissues, especially ..
  58. Matsumoto T, Kiriake A, Ishizaki S, Watabe S, Nagashima Y. Biliary excretion of tetrodotoxin in the cultured pufferfish Takifugu rubripes juvenile after intramuscular administration. Toxicon. 2015;93:98-102 pubmed publisher
    ..Here we investigated the tissue distribution and biliary excretion of TTX in cultured pufferfish Takifugu rubripes juveniles (6-month-old, 81.5 ± 2...
  59. Matsumoto T, Feroudj H, Kikuchi R, Kawana Y, Kondo H, Hirono I, et al. DNA Microarray Analysis on the Genes Differentially Expressed in the Liver of the Pufferfish, Takifugu rubripes, Following an Intramuscular Administration of Tetrodotoxin. Microarrays (Basel). 2014;3:226-44 pubmed publisher
    ..study aims at investigating the effect of TTX accumulation in the liver of cultured specimens of torafugu Takifugu rubripes on the hepatic gene expression by microarray analysis on Day 5 after the intramuscular administration of 0...
  60. Yamaguchi F, Macrae A, Brenner S. Molecular cloning of two cannabinoid type 1-like receptor genes from the puffer fish Fugu rubripes. Genomics. 1996;35:603-5 pubmed
    The puffer fish, Fugu rubripes (Fugu), has been proposed as a model vertebrate genome...
  61. Rapedius M, Haider S, Browne K, Shang L, Sansom M, Baukrowitz T, et al. Structural and functional analysis of the putative pH sensor in the Kir1.1 (ROMK) potassium channel. EMBO Rep. 2006;7:611-6 pubmed publisher
    ..We show that a Kir1.1 orthologue from Fugu rubripes lacks this lysine and yet is still highly pH sensitive, indicating that K80 is not the H+ sensor...
  62. Kurokawa T, Murashita K, Uji S. Characterization and tissue distribution of multiple agouti-family genes in pufferfish, Takifugu rubripes. Peptides. 2006;27:3165-75 pubmed publisher
    Four types of agouti-family genes (AGRP1, AGRP2, ASIP1 and ASIP2) were obtained from torafugu, Takifugu rubripes. Their characterization and structure were analyzed to elucidate the relationship among the torafugu agouti-family genes...
  63. Morimoto T, Biswas G, Kono T, Sakai M, Hikima J. Immune responses in the Japanese pufferfish (Takifugu rubripes) head kidney cells stimulated with particulate silica. Fish Shellfish Immunol. 2016;49:84-90 pubmed publisher
    ..we examined expression of cytokine genes related to innate immunity in the Japanese pufferfish, Fugu (Takifugu rubripes) head kidney (HK) cells stimulated with particulate silica at 10 and 50 μg mL(-1)...
  64. Miyazaki T, Kondrashev S, Tsuchiya T. Visual pigment genes and absorbance spectra in the Japanese sardine Sardinops melanostictus (Teleostei: Clupeiformes). Comp Biochem Physiol B Biochem Mol Biol. 2018;218:54-63 pubmed publisher
    ..However, unexpectedly, the RH2 sequences were more similar to orthologs in members of the Euteleosteomorpha (e.g., Oryzias latipes and Takifugu rubripes) than to cyprinid RH2 opsins.
  65. Verma Kurvari S, Johnson J. Identification of an achaete-scute homolog, Fash1, from Fugu rubripes. Gene. 1997;200:145-8 pubmed
    ..Here, we report the cloning and characterization of a Japanese pufferfish, Fugu rubripes achaete-scute homolog 1, Fash1...
  66. Zend Ajusch E, Hornung U, Burgtorf C, Lütjens G, Shan Z, Schartl M, et al. Isolation and characterization of cold-shock domain protein genes, Oryzias latipes Y-box protein 2 (OlaYP2) and Fugu rubripes Y-box protein 1 (FruYP1), in medakafish and pufferfish. Gene. 2002;296:111-9 pubmed
    ..Here we report the isolation of two teleost YP genes, medakafish Oryzias latipes (Ola)YP2 and Fugu rubripes (Fru)YP1, which are expressed in multiple tissues...
  67. Kondo H, Morinaga K, Misaki R, Nakaya M, Watabe S. Characterization of the pufferfish Takifugu rubripes apolipoprotein multigene family. Gene. 2005;346:257-66 pubmed publisher
    We have characterized the apolipoprotein multigene family of the pufferfish Takifugu rubripes. The pufferfish mainly contains 28-kDa, 27-kDa, and 14-kDa apolipoproteins in its plasma and was designated apo-28 kDa, apo-27 kDa, and apo-14 ..
  68. Suetake H, Saha N, Araki K, Akatsu K, Kikuchi K, Suzuki Y. Lymphocyte surface marker genes in fugu. Comp Biochem Physiol Part D Genomics Proteomics. 2006;1:102-8 pubmed publisher
    ..g. antibodies) to identify immune cells. The genomic sequence of Takifugu rubripes (fugu) represents an important resource to facilitate the identification of lymphocyte-related genes...
  69. Li J, Ai H, Zhang J, Du M, Zhang Z, Zhang J, et al. Molecular cloning, functional characterization and phylogenetic analysis of TRAIL in Japanese pufferfish Takifugu rubripes. J Fish Biol. 2011;79:747-60 pubmed publisher
    In this study, the complementary DNA (cDNA) of Japanese pufferfish Takifugu rubripes tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) was cloned by reverse-transcription PCR...
  70. Tatsuno R, Yamaguchi K, Takatani T, Arakawa O. RT-PCR- and MALDI-TOF mass spectrometry-based identification and discrimination of isoforms homologous to pufferfish saxitoxin- and tetrodotoxin-binding protein in the plasma of non-toxic cultured pufferfish (Takifugu rubripes). Biosci Biotechnol Biochem. 2013;77:208-12 pubmed
    Four genes of Takifugu rubripes, tentatively designated Tr1-Tr4, encoding homologs of pufferfish saxitoxin- and tetrodotoxin-binding protein, were identified by BLAST search and 3'-RACE...
  71. Islam Z, Hayashi N, Inoue H, Umezawa T, Kimura Y, Doi H, et al. Identification and lateral membrane localization of cyclin M3, likely to be involved in renal Mg2+ handling in seawater fish. Am J Physiol Regul Integr Comp Physiol. 2014;307:R525-37 pubmed publisher
    ..teleosts, we analyzed the expression of the Cnnm family genes in the seawater (SW) pufferfish, torafugu (Takifugu rubripes), and the closely related euryhaline species, mefugu (Takifugu obscurus)...
  72. Tsutsui S, Yamamura N, Yoshida T, Nakamura O. Fugu (Takifugu rubripes) serum GlcNAc-binding lectin is a kalliklectin but has different properties from those of a reported homologue. J Biochem. 2015;158:189-95 pubmed publisher
    A 40-kDa lectin with N-acetyl-d-glucosamine-binding ability was purified from the sera of fugu (Takifugu rubripes) by affinity chromatography and subsequent gel filtration...
  73. Ahammad A, Asaduzzaman M, Asakawa S, Watabe S, Kinoshita S. Regulation of gene expression mediating indeterminate muscle growth in teleosts. Mech Dev. 2015;137:53-65 pubmed publisher
    ..However, the molecular mechanism(s) underlying this property is unknown. Here, we focused on the torafugu (Takifugu rubripes) myosin heavy chain gene, MYHM2528-1, which is specifically expressed in neonatal muscle fibers produced by ..
  74. Yu X, Chen L, Cui W, Xing B, Zhuang X, Zhang G. Effects of acute temperature and salinity changes, body length and starvation on the critical swimming speed of juvenile tiger puffer, Takifugu rubripes. Fish Physiol Biochem. 2018;44:311-318 pubmed publisher
    The critical swimming speed (U crit, cm s-1) of juvenile tiger puffer Takifugu rubripes was determined under different temperatures (15, 21, 25 and 30 °C), salinities (5, 10, 20, 32 and 40), body lengths (3.32, 4...
  75. Odaka T, Suetake H, Maeda T, Miyadai T. Teleost Basophils Have IgM-Dependent and Dual Ig-Independent Degranulation Systems. J Immunol. 2018;200:2767-2776 pubmed publisher
    ..In this study, we characterized the teleost basophils that are abundant in the peripheral blood of fugu (Takifugu rubripes). Fugu basophils have two distinct granules: reddish-purple and dark violet ones...
  76. Tasumi S, Yamaguchi A, Matsunaga R, Fukushi K, Suzuki Y, Nakamura O, et al. Identification and characterization of pufflectin from the grass pufferfish Takifugu niphobles and comparison of its expression with that of Takifugu rubripes. Dev Comp Immunol. 2016;59:48-56 pubmed publisher
    Pufflectin found in Takifugu rubripes (Tr pufflectin) is the first animal lectin reported to show sequence similarity to monocotyledonous plant lectins...
  77. Fukuzawa T, Hirose S. Multiple processing of Ig-Hepta/GPR116, a G protein-coupled receptor with immunoglobulin (Ig)-like repeats, and generation of EGF2-like fragment. J Biochem. 2006;140:445-52 pubmed publisher
    ..Expression of some mRNA species was affected by the presence of alpha-fragment. These results suggest that the furin-processed alpha-fragment is involved in cellular signaling...
  78. Ebert A, McAnelly C, Srinivasan A, Mueller R, Garrity D, Garrity D. The calcium channel beta2 (CACNB2) subunit repertoire in teleosts. BMC Mol Biol. 2008;9:38 pubmed publisher
    ..In the Tetraodon nigrovidis and Fugu rubripes genomes, we identified single beta2 subunit gene loci...
  79. Inoue K, Naruse K, Yamagami S, Mitani H, Suzuki N, Takei Y. Four functionally distinct C-type natriuretic peptides found in fish reveal evolutionary history of the natriuretic peptide system. Proc Natl Acad Sci U S A. 2003;100:10079-84 pubmed publisher
    ..we found, by cDNA cloning, four distinct CNPs (1 through 4) in the medaka (Oryzias latipes) and puffer fish (Takifugu rubripes), although to our knowledge no more than two CNPs have been isolated from a vertebrate species...
  80. Siddique B, Kinoshita S, Wongkarangkana C, Asakawa S, Watabe S. Evolution and Distribution of Teleost myomiRNAs: Functionally Diversified myomiRs in Teleosts. Mar Biotechnol (NY). 2016;18:436-47 pubmed publisher
    ..In medaka and torafugu, miR-499 was highly expressed in slow/cardiac muscles whereas the expression of miR-736 was quite low and not ..
  81. Merson R, Karchner S, Hahn M. Interaction of fish aryl hydrocarbon receptor paralogs (AHR1 and AHR2) with the retinoblastoma protein. Aquat Toxicol. 2009;94:47-55 pubmed publisher
    ..These results suggest that both fish AHR1 and AHR2 paralogs may have the potential to influence cell proliferation through interactions with RB. ..
  82. Slavov D, Clark M, Gardiner K. Comparative analysis of the RED1 and RED2 A-to-I RNA editing genes from mammals, pufferfish and zebrafish. Gene. 2000;250:41-51 pubmed
    ..conservation among these editases, we have isolated homologous genes from the Japanese pufferfish, Fugu rubripes. Fugu has two genes homologous to Red1 that are similar in size and organization and that show a fivefold ..
  83. Trueb B, Neuhauss S, Baertschi S, Rieckmann T, Schild C, Taeschler S. Fish possess multiple copies of fgfrl1, the gene for a novel FGF receptor. Biochim Biophys Acta. 2005;1727:65-74 pubmed publisher
    ..A clear difference is observed in the ovary of Fugu rubripes, which expresses fgfrl1a but not fgfrl1b...
  84. Jiang J, Mao M, Lü H, Wen S, Sun M, Liu R, et al. Digital gene expression analysis of Takifugu rubripes brain after acute hypoxia exposure using next-generation sequencing. Comp Biochem Physiol Part D Genomics Proteomics. 2017;24:12-18 pubmed publisher
    ..In this study, a subset of genes in the brain of Takifugu rubripes were analyzed using digital gene expression (DGE) profiles and next-generation sequencing after acute ..
  85. Abrahams B, Mak G, Berry M, Palmquist D, Saionz J, Tay A, et al. Novel vertebrate genes and putative regulatory elements identified at kidney disease and NR2E1/fierce loci. Genomics. 2002;80:45-53 pubmed
    ..also contain the mouse kidney disease (kd) allele, we compared sequence from human, mouse, and the puffer fish Fugu rubripes. We identified a novel gene, c222389, containing conserved elements in noncoding regions...
  86. Itoi S, Kozaki A, Komori K, Tsunashima T, Noguchi S, Kawane M, et al. Toxic Takifugu pardalis eggs found in Takifugu niphobles gut: Implications for TTX accumulation in the pufferfish. Toxicon. 2015;108:141-6 pubmed publisher
    ..Toxification experiments in recirculating aquaria demonstrated that cultured Takifugu rubripes quickly became toxic upon being fed toxic (TTX-containing) T. rubripes eggs. These results suggest that T...
  87. Ramel M, Buckles G, Lekven A. Conservation of structure and functional divergence of duplicated Wnt8s in pufferfish. Dev Dyn. 2004;231:441-8 pubmed publisher
    ..are more widespread (and perhaps universal) among teleosts, we have extended our studies to the pufferfish Takifugu rubripes. We have found that Takifugu wnt8 is also bicistronic, indicating that the wnt8 duplication occurred before ..
  88. Kawaguchi M, Yasumasu S, Hiroi J, Naruse K, Suzuki T, Iuchi I. Analysis of the exon-intron structures of fish, amphibian, bird and mammalian hatching enzyme genes, with special reference to the intron loss evolution of hatching enzyme genes in Teleostei. Gene. 2007;392:77-88 pubmed publisher
    ..enzyme) was found only in the acanthopterygian fishes such as medaka Oryzias latipes, Fundulus heteroclitus, Takifugu rubripes and Tetraodon nigroviridis...
  89. Santagati F, Gerber J, Blusch J, Kokubu C, Peters H, Adamski J, et al. Comparative analysis of the genomic organization of Pax9 and its conserved physical association with Nkx2-9 in the human, mouse, and pufferfish genomes. Mamm Genome. 2001;12:232-7 pubmed publisher
    ..the Pax9 gene in three vertebrate species, humans, mice (Mus musculus), and the Japanese pufferfish (Fugu rubripes)...
  90. Xu B, Chen K, Yao Y, Liu Q, Xiao T, Su J, et al. Cloning, characterization and expression analysis of coagulation factor II gene in grass carp (Ctenopharyngodon idella). Genet Mol Res. 2015;14:13764-78 pubmed publisher
    ..Amino acid sequence comparisons indicated that grass carp FII showed most similarity (71%) to FII of Takifugu rubripes, followed by Oplegnathus fasciatus (48% similarity) and Larimichthys crocea (47% similarity)...
  91. Ohtani M, Miyadai T, Hiroishi S. Molecular cloning of the BCL-6 gene, a transcriptional repressor for B-cell differentiation, in torafugu (Takifugu rubripes). Mol Immunol. 2006;43:1047-53 pubmed
    ..In this study, we identified the BCL-6 gene in torafugu (Takifugu rubripes) using the torafugu genome database, and analyzed the expression of BCL-6 mRNA in various tissues of ..
  92. Cottage A, Edwards Y, Elgar G. SAND, a new protein family: from nucleic acid to protein structure and function prediction. Comp Funct Genomics. 2001;2:226-35 pubmed publisher
    ..In the course of our analysis of genomic sequence from Fugu rubripes, we identified a novel gene, SAND, with significant sequence identity to hypothetical proteins predicted in ..