bastard halibut

Summary

Alias: Japanese flounder, false halibut, olive flounder, Paralichthys olivaceus, Paralichthys olivaceous, Paralichtys olivaceus, Hippoglossus olivaceus, Paralichthy solivaceus, Paralichthyidae sp. KYJ-2011, Paralichthys olivaceus (Temminck & Schlegel, 1846)

Top Publications

  1. Li S, Li X, Gen X, Chen Y, Wei J, Sun J. Identification and characterization of lipopolysaccharide-induced TNF-alpha factor gene from Japanese flounder Paralichthys olivaceus. Vet Immunol Immunopathol. 2014;157:182-9 pubmed publisher
    ..In this study, a full-length LITAF cDNA, termed PoLITAF, was identified from Japanese flounder Paralichthys olivaceus. PoLITAF contains a 67 bp 5'-untranslated sequence, a 435 bp open reading frame, and a 647 bp 3'-..
  2. Choi S, Kim M, Kim K. Generation of killed but metabolically active (KBMA) Edwardsiella tarda and evaluation of its potential as a protective vaccine. Fish Shellfish Immunol. 2015;45:889-94 pubmed publisher
    ..generated KBMA Edwardsiella tarda and evaluated its potential as a protective vaccine in olive flounder (Paralichthys olivaceus)...
  3. Liu F, Tang X, Sheng X, Xing J, Zhan W. Comparative study of the vaccine potential of six outer membrane proteins of Edwardsiella tarda and the immune responses of flounder (Paralichthys olivaceus) after vaccination. Vet Immunol Immunopathol. 2017;185:38-47 pubmed publisher
    ..tarda and induce stronger immune responses in flounder, which indicates that OmpI and OmpX are promising vaccine candidates against E. tarda infection. ..
  4. Liu F, Tang X, Sheng X, Xing J, Zhan W. Edwardsiella tarda Outer Membrane Protein C: An Immunogenic Protein Induces Highly Protective Effects in Flounder (Paralichthys olivaceus) against Edwardsiellosis. Int J Mol Sci. 2016;17: pubmed publisher
    ..cell surface antigen and it was identified to be an immunogenic protein by Western blot using flounder (Paralichthys olivaceus) anti-recombinant OmpC (rOmpC), and anti-E. tarda antibodies...
  5. Du Y, Tang X, Sheng X, Xing J, Zhan W. Immune response of flounder (Paralichthys olivaceus) was associated with the concentration of inactivated Edwardsiella tarda and immersion time. Vet Immunol Immunopathol. 2015;167:44-50 pubmed publisher
    ..tarda under 10(8) CFU ml(-1) for 60 min induced the highest immune response of flounder against E. tarda bacterin, which might be applied for the control of edwardsiellosis in flounder. ..
  6. Xing J, Wang L, Zhen M, Tang X, Zhan W. Variations of T and B lymphocytes of flounder (Paralichthys olivaceus) after Hirame novirhabdovirus infection and immunization. Mol Immunol. 2018;96:19-27 pubmed publisher
    ..and IgM+ B lymphocytes presented in the peripheral blood leukocytes (PBLs) of flounder (Paralichthys olivaceus), in this paper, the variations of T and B lymphocytes of flounder after Hirame novirhabdovirus (HIRRV) ..
  7. Wang L, Fan C, Xu W, Zhang Y, Dong Z, Xiang J, et al. Characterization and functional analysis of a novel C1q-domain-containing protein in Japanese flounder (Paralichthys olivaceus). Dev Comp Immunol. 2017;67:322-332 pubmed publisher
    ..In this study, PoC1ql3 encoding a C1q-domain-containing protein in the Japanese flounder was identified...
  8. Cho H, Kim J, Moon J, Nam B, Kim Y, Kim W, et al. Microarray analysis of gene expression in olive flounder liver infected with viral haemorrhagic septicaemia virus (VHSV). Fish Shellfish Immunol. 2016;49:66-78 pubmed publisher
    The most fatal viral pathogen in olive flounder Paralichthys olivaceus, is viral hemorrhagic septicemia virus, which afflicts over 48 species of freshwater and marine fish...
  9. Kim M, Lee S, Kim D, Kim K. Generation of Recombinant Viral Hemorrhagic Septicemia Virus (rVHSV) Expressing Two Foreign Proteins and Effect of Lengthened Viral Genome on Viral Growth and In Vivo Virulence. Mol Biotechnol. 2016;58:280-6 pubmed publisher
    ..lengthened recombinant VHSV's genome on the replication ability and in vivo virulence to olive flounder (Paralichthys olivaceus) fingerlings were compared with previously generated rVHSVs (rVHSV-wild, rVHSV-Arfp, and rVHSV-Brfp)...

More Information

Publications291 found, 100 shown here

  1. Kim M, Choi S, Yang J, Kim K. Production of RNase III-knockout, auxotrophic Edwardsiella tarda mutant for delivery of long double-stranded RNA and evaluation of its immunostimulatory potential. Fish Shellfish Immunol. 2017;68:474-478 pubmed publisher
    ..Olive flounder (Paralichthys olivaceus) fingerlings administered the long dsRNA-producing auxotrophic E...
  2. Liu F, Tang X, Sheng X, Xing J, Zhan W. DNA vaccine encoding molecular chaperone GroEL of Edwardsiella tarda confers protective efficacy against edwardsiellosis. Mol Immunol. 2016;79:55-65 pubmed publisher
    In the present study, molecular chaperone GroEL of Edwardsiella tarda was found both react with flounder (Paralichthys olivaceus) anti-recombinant GroEL (rGroEL) and anti-E...
  3. Qin C, Shao T, Zhao D, Duan H, Wen Z, Yuan D, et al. Effect of ammonia-N and pathogen challenge on complement component 8? and 8? expression in the darkbarbel catfish Pelteobagrus vachellii. Fish Shellfish Immunol. 2017;62:107-115 pubmed publisher
    ..had the highest amino acid identity with rainbow trout Oncorhynchus mykiss C8? (62%) and Japanese flounder Paralichthys olivaceus C8? (83%), respectively...
  4. Zhang H, Hu G, Liu Q, Zhang S. Cloning and expression study of a Toll-like receptor 2 (tlr2) gene from turbot, Scophthalmus maximus. Fish Shellfish Immunol. 2016;59:137-148 pubmed publisher
    ..The deduced protein shows the highest sequence identity (76.1%) to Japanese flounder Tlr2 and possesses a signal peptide sequence, a leucine-rich repeat (LRR) domain composed of 19 LRR motifs, ..
  5. Liu F, Tang X, Sheng X, Xing J, Zhan W. Construction and evaluation of an Edwardsiella tarda DNA vaccine encoding outer membrane protein C. Microb Pathog. 2017;104:238-247 pubmed publisher
    ..encoding OmpC (pCG-OmpC) gene was constructed and its vaccine potential was analyzed in a flounder (Paralichthys olivaceus) model. The results showed that pCG-OmpC produced a relative percent survival (RPS) of 55% following E...
  6. Li Z, Liu X, Sun Y, Liu J, Liu Y, Wang M, et al. Roles of GATA6 during Gonadal Development in Japanese Flounder: Gonadogenesis, Regulation of Gender-Related Genes, Estrogen Formation and Gonadal Function Maintenance. Int J Mol Sci. 2017;18: pubmed publisher
    ..In this study, the full-length cDNA of GATA6 of Paralichthys olivaceus (Japanese flounder) was obtained...
  7. Sun Y, Hu Y. Cell-penetrating peptide-mediated subunit vaccine generates a potent immune response and protection against Streptococcus iniae in Japanese flounder (Paralichthys olivaceus). Vet Immunol Immunopathol. 2015;167:96-103 pubmed publisher
    ..that rTAT-Sia10 could penetrate into the head kidney lymphocytes and gill cells of Japanese flounder (Paralichthys olivaceus)...
  8. Liu S, Du Y, Sheng X, Tang X, Xing J, Zhan W. Molecular cloning of polymeric immunoglobulin receptor-like (pIgRL) in flounder (Paralichthys olivaceus) and its expression in response to immunization with inactivated Vibrio anguillarum. Fish Shellfish Immunol. 2019;87:524-533 pubmed publisher
    In the present work, the polymeric immunoglobulin receptor-like (pIgRL) from flounder (Paralichthys olivaceus) was firstly cloned and identified...
  9. Ni F, Liu Y, Meng L, Yan W, Zhang Q, Yu H, et al. Roles of piwil1 gene in gonad development and gametogenesis in Japanese flounder, Paralichthys olivaceus. Gene. 2019;701:104-112 pubmed publisher
    ..In this study, we analyzed the piwil1 gene in Paralichthys olivaceus. Bioinformatics analysis and structure prediction showed that piwil1 had the conserved domains: PAZ domain ..
  10. Liu J, Cao D, Liu Y, Li Z, Si Y, Wang Z, et al. Expression and functional analysis of receptor-interacting serine/threonine kinase 2 (RIP2) in Japanese flounder (Paralichthys olivaceus). Fish Shellfish Immunol. 2018;75:327-335 pubmed publisher
    ..In this study, we identified and characterized the Paralichthys olivaceus RIP2 gene (PoRIP2)...
  11. Palanisamy R, Kumaresan V, Harikrishnan R, Arasu M, Al Dhabi N, Arockiaraj J. Functional roles and gene regulation of tumor necrosis factor receptor 1 in freshwater striped murrel. Mol Immunol. 2015;66:240-52 pubmed publisher
    ..3. CsTNFR1 shared maximum identity with TNFR1 from olive flounder Paralichthys olivaceus (82%). Real-time PCR showed that CsTNFR1 gene was expressed most abundantly (P<0.05) in the head kidney...
  12. Fan L, Jiang J, Gao J, Song H, Liu J, Yang L, et al. Identification and Characterization of a PRDM14 Homolog in Japanese Flounder (Paralichthys olivaceus). Int J Mol Sci. 2015;16:9097-118 pubmed publisher
    ..In this study, we cloned the full-length cDNA and genomic DNA of the Paralichthys olivaceus prdm14 (Po-prdm14) gene and isolated the 5' regulatory region of Po-prdm14 by whole-genome sequencing...
  13. Hu G, Zhang S, Yang X, Liu D, Liu Q, Zhang S. Cloning and expression analysis of a Toll-like receptor 22 (tlr22) gene from turbot, Scophthalmus maximus. Fish Shellfish Immunol. 2015;44:399-409 pubmed publisher
    ..The deduced protein shows the highest sequence identity (76.7%) to Japanese flounder Tlr22 and possesses a signal peptide sequence, a leucine-rich repeat (LRR) domain composed of 27 LRR motifs, ..
  14. Gao Y, Tang X, Sheng X, Xing J, Zhan W. Antigen uptake and expression of antigen presentation-related immune genes in flounder (Paralichthys olivaceus) after vaccination with an inactivated Edwardsiella tarda immersion vaccine, following hyperosmotic treatment. Fish Shellfish Immunol. 2016;55:274-80 pubmed publisher
    ..In the present work, flounders (Paralichthys olivaceus) were immersed in three hyperosmotic solutions with 40, 50 and 60‰ salinities, then transferred into ..
  15. Xing J, Li P, Tang X, Zhan W. Recombinant Hsp33 and OmpC protein can serve as promising divalent vaccine with protection against Vibrio anguillarum and Edwardsiella tarda in flounder (Paralichthys olivaceus). Fish Shellfish Immunol. 2018;74:341-348 pubmed publisher
    ..severe aquaculture pathogens shared similar epidemiological characteristics and susceptible to flounder (Paralichthys olivaceus). In our previous studies, recombinant(r) protein heat shock protein 33 (rHsp33) from V...
  16. Cho S, Kwon Y, Nam M, Vaidya B, Kim S, Lee S, et al. Integrated profiling of global metabolomic and transcriptomic responses to viral hemorrhagic septicemia virus infection in olive flounder. Fish Shellfish Immunol. 2017;71:220-229 pubmed publisher
    ..time-of-flight mass spectroscopy to investigate the mechanisms of VHSV infection in the kidneys of olive flounder. A total of 13,862 mRNA molecules and 72 metabolites were selected to identify the mechanisms of infection and ..
  17. Hwang J, Jeong J, Kwon M, Seo J, Hwang S, Son M, et al. Olive flounder CD276 (B7-H3) a coinhibitory molecule for T cells: Responses during viral hemorrhagic septicemia virus (VHSV) stimulation. Fish Shellfish Immunol. 2018;73:228-233 pubmed publisher
    ..We have characterized the CD276 gene of olive flounder, Paralichthys olivaceus. OfCD276 has an ORF of 912 bp that codes for 303 amino acids with a predicted molecular mass of 33?kDa...
  18. Hu Y, Zhou H, Jin Q, Zhang J. The serine protease autotransporter Tsh contributes to the virulence of Edwardsiella tarda. Vet Microbiol. 2016;189:68-74 pubmed publisher
    ..coli as a recombinant protein (rPepS). When used as a subunit vaccine to immunize Japanese flounder, rPepS was able to induce effective immune protection...
  19. Li X, Yu H, Wang Y, Liu X, Liu Y, Qu J, et al. Roles of Two Sox9 Genes during Gonadal Development in Japanese Flounder: Sex Differentiation, Spermatogenesis and Gonadal Function Maintenance. Int J Mol Sci. 2018;19: pubmed publisher
    ..Here, two duplicates of sox9 were found in Japanese flounder (Paralichthys olivaceus) named Posox9a and Posox9b, respectively...
  20. Tang X, Liu F, Sheng X, Xing J, Zhan W. Recombinant NADP-dependent isocitrate dehydrogenase of Edwardsiella tarda induces both Th1 and Th2 type immune responses and evokes protective efficacy against edwardsiellosis. Vaccine. 2018;36:2337-2345 pubmed publisher
    ..tarda was recombinantly expressed and flounder (Paralichthys olivaceus) anti-rIDH serum was prepared. Also, the outer membrane proteins (OMPs) of E...
  21. Sheng X, Liu M, Liu H, Tang X, Xing J, Zhan W. Identification of immunogenic proteins and evaluation of recombinant PDHA1 and GAPDH as potential vaccine candidates against Streptococcus iniae infection in flounder (Paralichthys olivaceus). PLoS ONE. 2018;13:e0195450 pubmed publisher
    ..5% and 75%, respectively) again. These results demonstrated that rPDHA1 and rGAPDH are promising vaccine candidates against S. iniae infection in flounder. ..
  22. Tang X, Gong J, Zeng C, Sheng X, Xing J, Zhan W. Dynamic distribution of formalin-inactivated Edwardsiella tarda in flounder (Paralichthys olivaceus) post intraperitoneal vaccination. Fish Shellfish Immunol. 2019;89:393-402 pubmed publisher
    ..an absolute real-time quantitative PCR was employed to detect the amount of antigen in flounder (Paralichthys olivaceus) post intraperitoneal (i.p...
  23. Lazarte J, Kim Y, Lee J, Im S, Kim S, Jung J, et al. Enhancement of glycoprotein-based DNA vaccine for viral hemorrhagic septicemia virus (VHSV) via addition of the molecular adjuvant, DDX41. Fish Shellfish Immunol. 2017;62:356-365 pubmed publisher
    ..To gain more information regarding G-based DNA vaccines in olive flounder (Paralicthys olivaceus), we tried to develop a more efficient G-based DNA vaccine by adding a molecular ..
  24. Rondón Barragán I, Nozaki R, Hirono I, Kondo H. LAMP-1-chimeric DNA vaccines enhance the antibody response in Japanese flounder, Paralichthys olivaceus. Fish Shellfish Immunol. 2017;67:546-553 pubmed publisher
    ..Here, we sequenced the gene encoding lysosome-associated membrane protein-1 from Japanese flounder, Paralichthys olivaceus, (JfLAMP-1) and assessed its use in a chimeric DNA vaccine fused with the major capsule protein (MCP) from ..
  25. Guo M, Tang X, Sheng X, Xing J, Zhan W. The effects of IL-1?, IL-8, G-CSF and TNF-? as molecular adjuvant on the immune response to an E. tarda subunit vaccine in flounder (Paralichthys olivaceus). Fish Shellfish Immunol. 2018;77:374-384 pubmed publisher
    ..In this study, the expression plasmid pcDNA3.1 (pcN3) encoding four flounder (Paralichthys olivaceus) cytokines including IL-1?, TNF-?, IL-8 or G-CSF (pcIL-1?, pcTNF-?, pcIL-8 and pcG-CSF) were successfully ..
  26. Liu C, Liu W, Fan L, Liu J, Li P, Zhang W, et al. Sequences analyses and expression profiles in tissues and embryos of Japanese flounder (Paralichthys olivaceus) PRDM1. Fish Physiol Biochem. 2016;42:467-82 pubmed publisher
    ..study, a gene coding the homolog of prdm1 and the 5' regulatory region of prdm1 was identified from the Paralichthys olivaceus (denoted Po-prdm1)...
  27. Du Y, Tang X, Zhan W, Xing J, Sheng X. Immunoglobulin Tau Heavy Chain (IgT) in Flounder, Paralichthys olivaceus: Molecular Cloning, Characterization, and Expression Analyses. Int J Mol Sci. 2016;17: pubmed publisher
    ..IgT (mIgT and sIgT) heavy chain genes were cloned for the first time and characterized in flounder (Paralichthys olivaceus), and found the nucleic acid sequence were exactly same in the C?1-C?4 constant domains of mIgT and sIgT, ..
  28. Jang Y, Subramanian D, Won S, Heo M. Immune response of olive flounder (Paralichthys olivaceus) infected with the myxosporean parasite Kudoa septempunctata. Fish Shellfish Immunol. 2017;67:172-178 pubmed publisher
    This study evaluated the pathophysiological, biochemical, and immunological status of olive flounder (Paralichthys olivaceus) infected with the myxosporean parasite Kudoa septempunctata...
  29. Xing J, Xiao Y, Tang X, Sheng X, Zhan W. Inhibition of Cyclosporine A or rapamycin on T lymphocyte counts and the influence on the immune responses of B lymphocytes in flounder (Paralichthys olivaceus). Fish Shellfish Immunol. 2017;66:78-85 pubmed publisher
    ..RaPa) were used, and their inhibition on T lymphocytes and immune responses of B lymphocytes in flounder (Paralichthys olivaceus) were investigated...
  30. Yasuike M, Nishiki I, Iwasaki Y, Nakamura Y, Fujiwara A, Sugaya E, et al. Full-genome sequence of a novel myovirus, GF-2, infecting Edwardsiella tarda: comparison with other Edwardsiella myoviral genomes. Arch Virol. 2015;160:2129-33 pubmed publisher
    ..myovirus morphology (family Myoviridae), isolated from tissue homogenates of a cultured Japanese flounder (Paralichthys olivaceus) that succumbed to edwardsiellosis in Japan...
  31. Liu X, Li Z, Wu W, Liu Y, Liu J, He Y, et al. Sequencing-based network analysis provides a core set of gene resource for understanding kidney immune response against Edwardsiella tarda infection in Japanese flounder. Fish Shellfish Immunol. 2017;67:643-654 pubmed publisher
    ..In this study, we performed transcriptome-wide gene expression profiling of the Japanese flounder (Paralichthys olivaceus) challenged by 8 and 48 h of E. tarda infection...
  32. Guo M, Tang X, Sheng X, Xing J, Zhan W. The Immune Adjuvant Effects of Flounder (Paralichthys olivaceus) Interleukin-6 on E. tarda Subunit Vaccine OmpV. Int J Mol Sci. 2017;18: pubmed publisher
    ..In this study, the immune adjuvant effects of two forms of flounder (Paralichthys olivaceus) IL-6, including recombinant IL-6 (rIL-6) and pcDNA3...
  33. Huang Y, Wen H, Zhang M, Hu N, Si Y, Li S, et al. The DNA methylation status of MyoD and IGF-I genes are correlated with muscle growth during different developmental stages of Japanese flounder (Paralichthys olivaceus). Comp Biochem Physiol B Biochem Mol Biol. 2018;219-220:33-43 pubmed publisher
    ..DNA methylation and mRNA expression patterns of MyoD and IGF-I during different developmental stages of Japanese flounder, and to examine the relationship between MyoD and IGF-I gene...
  34. Su Y, Fu Y, Zhang H, Shi Z, Zhang J, Gao L. Identification and expression of SRF targeted by miR-133a during early development of Paralichthys olivaceus. Fish Physiol Biochem. 2015;41:1093-104 pubmed publisher
  35. Deng K, Pan M, Liu J, Yang M, Gu Z, Zhang Y, et al. Chronic stress of high dietary carbohydrate level causes inflammation and influences glucose transport through SOCS3 in Japanese flounder Paralichthys olivaceus. Sci Rep. 2018;8:7415 pubmed publisher
    ..the effects of high level of dietary carbohydrate on the survival, growth and immune responses of Paralichthys olivaceus, and the underlying molecular mechanism related to the immune and glucose metabolism. P...
  36. Wang L, Shao C, Xu W, Zhou Q, Wang N, Chen S. Proteome profiling reveals immune responses in Japanese flounder (Paralichthys olivaceus) infected with Edwardsiella tarda by iTRAQ analysis. Fish Shellfish Immunol. 2017;66:325-333 pubmed publisher
    ..The differential proteomic response of the Japanese flounder liver to Edwardsiella tarda infection was examined using isobaric tags for relative and absolute ..
  37. Zou G, Nozaki R, Kondo H, Hirono I. Cloning and expression analysis of three novel CC chemokine genes from Japanese flounder (Paralichthys olivaceus). Fish Shellfish Immunol. 2014;40:507-13 pubmed publisher
    ..In this study, three novel CC chemokine genes Paol-SCYA105, 106 and 107 in Japanese flounder (Paralichthys olivaceus) were cloned and characterized...
  38. Gao J, Wang X, Zhang Q. Evolutionary Conservation of pou5f3 Genomic Organization and Its Dynamic Distribution during Embryogenesis and in Adult Gonads in Japanese Flounder Paralichthys olivaceus. Int J Mol Sci. 2017;18: pubmed publisher
    ..In this study, we isolated the full-length sequence of Paralichthys olivaceus pou5f3 (Popou5f3), and we found that it is homologous to mammalian Oct4...
  39. Kondo H, Kawana Y, Suzuki Y, Hirono I. Comprehensive gene expression profiling in Japanese flounder kidney after injection with two different formalin-killed pathogenic bacteria. Fish Shellfish Immunol. 2014;41:437-40 pubmed publisher
    ..investigate the gene expression profiles regulated by different bacterial components in Japanese flounder Paralichthys olivaceus, Japanese flounder were intraperitoneally injected with formalin-killed bacterial cells (FKC) of ..
  40. Liu D, Guo B, Han D, Deng K, Gu Z, Yang M, et al. Comparatively study on the insulin-regulated glucose homeostasis through brain-gut peptides in Japanese flounder Paralichthys olivaceus after intraperitoneal and oral administration of glucose. Gen Comp Endocrinol. 2018;266:9-20 pubmed publisher
    ..and spatial expression of brain-gut peptides and the key enzymes of glycolysis and gluconeogenesis in Japanese flounder by intraperitoneal injection (IP) and oral administration (OR) of glucose...
  41. Kasai A, Tsuduki H, Jimenez L, Li Y, Tanaka S, Sato H. Incidence of three Kudoa spp., K. neothunni, K. hexapunctata, and K. thunni (Myxosporea: Multivalvulida), in Thunnus tunas distributed in the western Pacific Ocean. Parasitol Res. 2017;116:1137-1150 pubmed publisher
    ..has been identified as live Kudoa septempunctata (Myxosporea: Multivalvulida) in the olive flounder (Paralichthys olivaceus)...
  42. Jo A, Im J, Lee H, Jang D, Nam G, Mishra A, et al. Evolutionary conservation and expression of miR-10a-3p in olive flounder and rock bream. Gene. 2017;628:16-23 pubmed publisher
    ..Here, the evolutionary conservation and expression pattern of miR-10a-3p in olive flounder and rock bream was examined...
  43. Shakeela Q, Shehzad A, Tang K, Zhang Y, Zhang X. Ichthyenterobacterium magnum gen. nov., sp. nov., a member of the family Flavobacteriaceae isolated from olive flounder (Paralichthys olivaceus). Int J Syst Evol Microbiol. 2015;65:1186-92 pubmed publisher
    A novel marine bacterium isolated from the intestine of cultured flounder (Paralichthys olivaceus) was studied by using a polyphasic taxonomic approach...
  44. Li M, Tan X, Sui Y, Jiao S, Wu Z, Wang L, et al. The stimulatory effect of neuropeptide Y on growth hormone expression, food intake, and growth in olive flounder (Paralichthys olivaceus). Fish Physiol Biochem. 2017;43:11-18 pubmed publisher
    ..In this study, we investigated the effect of NPY on food intake and growth in the olive flounder (Paralichthys olivaceus)...
  45. Chen Y, Zhang Y, Zhu R, Zhang F, Jiang J, Shi Y, et al. Inductive expression and characterization analysis of Paralichthys olivaceus pigment epithelium-derived factor in a virally infected cell line. Biochem Biophys Res Commun. 2005;335:799-809 pubmed
    ..Here, A PEDF gene homolog, Paralichthys olivaceus PEDF (PoPEDF), was isolated from flounder embryonic cells (FEC) treated with UV-inactivated Grass carp ..
  46. Kato G, Kondo H, Aoki T, Hirono I. A novel immune-related gene, microtubule aggregate protein homologue, is up-regulated during IFN-?-related immune responses in Japanese flounder, Paralichthys olivaceus. Dev Comp Immunol. 2012;36:349-58 pubmed publisher
    ..Japanese flounder (Paralichthys olivaceus) microtubule aggregate protein homologue (PoMTAP) was identified as a gene strongly induced during fish ..
  47. Zhang B, Zhang J, Sun L. In-depth profiling and analysis of host and viral microRNAs in Japanese flounder (Paralichthys olivaceus) infected with megalocytivirus reveal involvement of microRNAs in host-virus interaction in teleost fish. BMC Genomics. 2014;15:878 pubmed publisher
    ..sequencing technology to identify and analyze both host and viral miRNAs in Japanese flounder (Paralichthys olivaceus), an economically important teleost fish farmed widely in the world, infected with megalocytivirus at a ..
  48. Kim S, Kim M, Choi G, Lee J, Kang J, Evensen Ã, et al. Stability and efficacy of the 3'-UTR A4G-G5A variant of viral hemorrhagic septicemia virus (VHSV) as a live attenuated immersion VHSV vaccine in olive flounder (Paralichthys olivaceus). Vaccine. 2016;34:1097-102 pubmed publisher
    ..septicemia in fish, a disease that affects a number of teleost fish species including olive flounder (Paralichthys olivaceus)...
  49. Wang X, He G, Mai K, Xu W, Zhou H. Differential regulation of taurine biosynthesis in rainbow trout and Japanese flounder. Sci Rep. 2016;6:21231 pubmed publisher
    ..In the present study, we examined the regulations of CDO and CSD in rainbow trout and Japanese flounder, the two fish species with high and low taurine biosynthesis ability respectively...
  50. Robledo D, Hermida M, Rubiolo J, Fernandez C, Blanco A, Bouza C, et al. Integrating genomic resources of flatfish (Pleuronectiformes) to boost aquaculture production. Comp Biochem Physiol Part D Genomics Proteomics. 2017;21:41-55 pubmed publisher
    ..The main farmed species is the turbot (Scophthalmus maximus) followed by Japanese flounder (Paralichthys olivaceous) and tongue sole (Cynoglossus semilaevis), but other species like Atlantic halibut (Hippoglossus ..
  51. Kono T, Sakai M. The analysis of expressed genes in the kidney of Japanese flounder, Paralichthys olivaceus, injected with the immunostimulant peptidoglycan. Fish Shellfish Immunol. 2001;11:357-66 pubmed publisher
    ..Therefore, in this study, expressed genes in the kidney of Japanese flounder Paralichthys olivaceus injected with the immunostimulant peptidoglycan were analysed...
  52. Zhou Z, Sun B, Sun L. Edwardsiella tarda Sip1: A serum-induced zinc metalloprotease that is essential to serum resistance and host infection. Vet Microbiol. 2015;177:332-40 pubmed publisher
    ..sip1 knockout mutant, TXΔsip1, was dramatically reduced in the ability to cause mortality in the host (Japanese flounder) and to survive in host serum...
  53. Zhao B, Katagiri T, Kondo H, Hirono I. Comparative analysis of two types of CXCL8 from Japanese flounder (Paralichthys olivaceus). Dev Comp Immunol. 2015;52:37-47 pubmed publisher
    A new type of CXCL8, named CXCL8_L1b, was identified in this research. Comparison of amino acid sequences of Japanese flounder CXCL8_L1b and CXCL8_L1a (BAB86884.1) showed only 41.2% identity...
  54. Xing J, Ma J, Tang X, Sheng X, Zhan W. Characterizations of CD4-1, CD4-2 and CD8β T cell subpopulations in peripheral blood leucocytes, spleen and head kidney of Japanese flounder (Paralichthys olivaceus). Mol Immunol. 2017;85:155-165 pubmed publisher
    ..antibodies against CD3 molecule have been produced and were used in labeling T cells in Japanese flounder (Paralichthys olivaceus)...
  55. Fu Y, Jia L, Shi Z, Zhang J, Li W. Gene expression patterns regulating embryogenesis based on the integrated de novo transcriptome assembly of the Japanese flounder. Comp Biochem Physiol Part D Genomics Proteomics. 2017;22:58-66 pubmed publisher
    The Japanese flounder (Paralichthys olivaceus) is one of the most important commercial and biological marine fishes...
  56. Xu X, Liu J, Wang Y, Si Y, Wang X, Wang Z, et al. Kunitz-type serine protease inhibitor is a novel participator in anti-bacterial and anti-inflammatory responses in Japanese flounder (Paralichthys olivaceus). Fish Shellfish Immunol. 2018;80:22-30 pubmed publisher
    ..In this study, a KSPI molecule was identified from Japanese flounder (Paralichthys olivaceus), and was named Pokspi...
  57. Lyu Z, Zhao B, Koiwai K, Hirono I, Kondo H. Identification of endonuclease domain-containing 1 gene in Japanese flounder Paralichthys olivaceus. Fish Shellfish Immunol. 2016;50:43-9 pubmed publisher
    The mRNA level of the endonuclease domain-containing 1 gene (Jf_ENDOD1) in Japanese flounder Paralichthys olivaceus kidney was significantly increased after injection of formalin-killed bacteria cells (FKC) in the previous microarray ..
  58. Wu S, Huang Y, Li S, Wen H, Zhang M, Li J, et al. DNA methylation levels and expression patterns of Smyd1a and Smyd1b genes during Metamorphosis of the Japanese Flounder (Paralichthys olivaceus). Comp Biochem Physiol B Biochem Mol Biol. 2018;223:16-22 pubmed publisher
    Japanese flounder (Paralichthys olivaceus) undergoes metamorphosis by changing its body from the larval to the juvenile form, and this process involves muscle development...
  59. Lee S, Lee Y, Kim K, Kim H, Park C, Park J, et al. Effects of food availability on growth performance and immune-related gene expression of juvenile olive flounder (Paralichthys olivaceus). Fish Shellfish Immunol. 2018;80:348-356 pubmed publisher
    ..food availability) on growth performance and immune-related gene expression of juvenile olive flounder (Paralichthys olivaceus)...
  60. Hirono I, Hwang J, Ono Y, Kurobe T, Ohira T, Nozaki R, et al. Two different types of hepcidins from the Japanese flounder Paralichthys olivaceus. FEBS J. 2005;272:5257-64 pubmed publisher
    ..we found two different types (designated Hep-JF1 and Hep-JF2) of hepcidin cDNA in the Japanese flounder, Paralichthys olivaceus, by expressed sequence tag analysis...
  61. Nam B, Moon J, Park E, Kim Y, Kim D, Kong H, et al. Antimicrobial activity of peptides derived from olive flounder lipopolysaccharide binding protein/bactericidal permeability-increasing protein (LBP/BPI). Mar Drugs. 2014;12:5240-57 pubmed publisher
    We describe the antimicrobial function of peptides derived from the C-terminus of the olive flounder LBP BPI precursor protein...
  62. Ohnishi T, Lim B, Nojima N, Kunitoshi O, Inagaki S, Makitsuru K, et al. Inter-Laboratory Study to Validate New Rapid Screening Methods for Kudoa septempunctata. Biocontrol Sci. 2016;21:135-8 pubmed publisher
    Kudoa septempunctata is the causative agent of a food-borne disease associated with the ingestion of raw olive flounder. As the current qRT-PCR method for its detection is time-consuming, a rapid and simple method is required...
  63. Zhou X, Xing J, Tang X, Zhan W. Evaluation of bivalent vaccines candidates among VAA, OmpK and OmpR from Vibrio anguillarum in flounder (Paralichthys olivaceus). Dev Comp Immunol. 2018;85:1-9 pubmed publisher
    ..92%, 78.49%, 82.09% and 56.99%, respectively. These results indicated that three bivalent vaccines AK, AR and KR could induce strong cellular and humoral immunity, and had high protection against V. anguillarum infection in flounders. ..
  64. Hu G, Yin X, Xia J, Dong X, Zhang J, Liu Q. Molecular cloning and characterization of interferon regulatory factor 7 (IRF-7) in Japanese flounder, Paralichthys olivaceus. Fish Shellfish Immunol. 2010;29:963-71 pubmed publisher
    ..In this study, a full-length cDNA of Japanese flounder, Paralichthys olivaceus, (Po)IRF-7 was cloned and characterized...
  65. Gao Q, Xiao Y, Zhang C, Min M, Peng S, Shi Z. Molecular characterization and expression analysis of toll-like receptor 2 in response to bacteria in silvery pomfret intestinal epithelial cells. Fish Shellfish Immunol. 2016;58:1-9 pubmed publisher
    ..Oplegnathus fasciatus, Epinephelus coioides, Larimichthys crocea, Miichthys miiuy, Oreochromis niloticus, Paralichthys olivaceus, Trematomus bernacchii, Sparus aurata, and Chionodraco hamatus exhibited a high degree of homology of 78...
  66. Yue Z, Yu M, Zhang X, Dong Y, Tian H, Wang W, et al. Semicarbazide-induced thyroid disruption in Japanese flounder (Paralichthys olivaceus) and its potential mechanisms. Ecotoxicol Environ Saf. 2017;140:131-140 pubmed publisher
    ..In this study, we exposed fertilized eggs of Japanese flounder (Paralichthys olivaceus) to 1, 10, 100, and 1000?g/L SMC for 55 d to assess the impact of SMC exposure on the thyroid system...
  67. Nam B, Moon J, Kim Y, Kong H, Kim W, Kim D, et al. Structural and functional characterization of pituitary adenylyl cyclase-activating polypeptide (PACAP)/PACAP-related peptide (PRP) and its receptor in olive flounder (Paralichthys olivaceus). Comp Biochem Physiol B Biochem Mol Biol. 2013;164:18-28 pubmed publisher
    ..polypeptide (PACAP), PACAP-related peptide (PRP), and PACAP-specific receptor (PAC1R) from olive flounder, Paralichthys olivaceus. Two variant mRNA forms were created by alternative splicing...
  68. Sugita Konishi Y, Fukuda Y, Mori K, Mekata T, Namba T, Kuroda M, et al. New validated rapid screening methods for identifying Kudoa septempunctata in olive flounder (Paralichthys olivaceus). Jpn J Infect Dis. 2015;68:145-7 pubmed publisher
    Kudoa septempunctata is a newly identified causative agent of foodborne diseases associated with consuming raw olive flounder. Qualitative PCR and quantitative real-time PCR have been used as notification methods to identify K...
  69. Hwang J, Kwon M, Kim Y, Jung S, Park M, Son M. Montanide IMS 1312 VG adjuvant enhances the efficacy of immersion vaccine of inactivated viral hemorrhagic septicemia virus (VHSV) in olive flounder, Paralichthys olivaceus. Fish Shellfish Immunol. 2017;60:420-425 pubmed publisher
    ..against viral hemorrhagic septicemia (VHS) containing Montanide IMS 1312 VG adjuvant in olive flounder (Paralichthys olivaceus)...
  70. Yuan J, Jiang J, Jiang L, Yang F, Chen Y, He Y, et al. Insights into Trx1, TRP14, and Prx1 homologs of Paralichthys olivaceus: molecular profiles and transcriptional responses to immune stimulations. Fish Physiol Biochem. 2016;42:547-61 pubmed publisher
    ..In this study, we isolated the full-length cDNAs of PoTrx1 and PoTRP14 from Japanese flounder (Paralichthys olivaceus). PoTrx1 is 723 bp in length, with a 366-bp open reading frame (ORF) that encodes for 121 amino acids...
  71. Li S, Hao G, Xu Y, Wang N, Li J, Geng X, et al. Functional characterization of purinergic P2Y2 and P2Y12 receptors involved in Japanese flounder (Paralichthys olivaceus) innate immune responses. Fish Shellfish Immunol. 2018;75:208-215 pubmed publisher
    ..we identified and characterized the P2Y2 and P2Y12 receptors in Japanese flounder Paralichthys olivaceus. The P...
  72. Kim M, Seo J, Ahn S, Kim N, Je J, Sung J, et al. Duplication of phospholipase C-delta gene family in fish genomes. Genomics. 2008;92:366-71 pubmed publisher
    ..phospholipase C-delta (PLC-delta), designated respectively PoPLC-deltas, from olive flounder (Paralichthys olivaceus), and we performed phylogenetic analysis and sequence comparison to compare our putative gene products (..
  73. Hu G, Zhao M, Lin J, Liu Q, Zhang S. Molecular cloning and characterization of interferon regulatory factor 9 (IRF9) in Japanese flounder, Paralichthys olivaceus. Fish Shellfish Immunol. 2014;39:138-44 pubmed publisher
    ..study, we studied the structure, mRNA tissue distribution and regulation of IRF9 from Japanese flounder, Paralichthys olivaceus. The cDNA sequence of IRF9 is 3305 bp long, containing an open reading frame (ORF) of 1308 bp that encodes ..
  74. Hwang J, Kwon M, Seo J, Do J, Park M, Jung S, et al. Differentially expressed genes after viral haemorrhagic septicaemia virus infection in olive flounder (Paralichthys olivaceus). Vet Microbiol. 2016;193:72-82 pubmed publisher
    A strain of viral haemorrhagic septicaemia virus (VHSV) was isolated from cultured olive flounder (Paralichthys olivaceus) during epizootics in South Korean...
  75. Kim N, Ahn S, Lee A, Seo J, Kim M, Kim J, et al. Cloning, expression analysis and enzymatic characterization of cathepsin S from olive flounder (Paralichthys olivaceus). Comp Biochem Physiol B Biochem Mol Biol. 2010;157:238-47 pubmed publisher
    ..In this study, we cloned a cDNA encoding for cathepsin S (PoCtS) from the olive flounder, Paralichthys olivaceus. The 1170 bp PoCtS cDNA contained an open reading frame of 1014 bp, which consisted of a 25-residue ..
  76. Liu Q, Ma D, Xu S, Xiao Z, Xiao Y, Song Z, et al. Summer flounder (Paralichthys dentatus) sperm cryopreservation and application in interspecific hybridization with olive flounder (P olivaceus). Theriogenology. 2015;83:703-10 pubmed publisher
    ..sperm cryopreservation, and successfully applied the cryopreserved sperm into interspecific hybridization with olive flounder (P olivaceus). The best motility of postthaw sperm (78.00 ± 4.70% and 76.60 ± 7...
  77. Cui Y, Wang H, Qiu X, Liu H, Yang R. Bayesian Analysis for Genetic Architectures of Body Weights and Morphological Traits Using Distorted Markers in Japanese Flounder Paralichthys olivaceus. Mar Biotechnol (NY). 2015;17:693-702 pubmed publisher
    ..mitotic gynogenetics for the study of genetic architectures of the body weight and morphological traits in Japanese flounder. Each DH individual is genotyped for 458 SSR markers, 222 of which segregate distortionally...
  78. Liu W, Song H, Li A, Du X, Liu Y, He Y, et al. Functional characterization of the Japanese flounder (Paralichthys olivaceus) Sox2 gene promoter. Fish Physiol Biochem. 2016;42:1275-85 pubmed publisher
    ..In our study, a 1.8-kb fragment of the 5' flanking region of Paralichthys olivaceus Sox2 (Po-Sox2) gene was cloned and functionally characterized...
  79. Zhang Y, Chen S, Liu Y, Sha Z, Liu Z. Major histocompatibility complex class IIB allele polymorphism and its association with resistance/susceptibility to Vibrio anguillarum in Japanese flounder (Paralichthys olivaceus). Mar Biotechnol (NY). 2006;8:600-10 pubmed
    ..length of major histocompatibility complex (MHC) class IIB cDNA was cloned from a Chinese population of Paralichthys olivaceus by homology cloning and rapid amplification of cDNA ends-polymerase chain reaction (RACE-PCR)...
  80. Yazawa R, Kondo H, Hirono I, Aoki T. Cloning and characterization of the IkappaBalpha gene from Japanese flounder, Paralichthys olivaceus. Fish Shellfish Immunol. 2007;23:808-14 pubmed
    We identified and characterized the Japanese flounder (Paralichthys olivaceus) inhibitor kappa B alpha (JFIKBA) cDNA. The JFIKBA cDNA contains an open reading frame of 960bp encoding 320 amino acid residues...
  81. Woo S, Park S. Effects of phosphoglucomutase gene (PGM) in Streptococcus parauberis on innate immune response and pathogenicity of olive flounder (Paralichthys olivaceus). Fish Shellfish Immunol. 2014;41:317-25 pubmed publisher
    ..immune clearance mechanisms including serum, mucus and phagocyte killing and could not induce mortality in olive flounder. These phenotype changes and the attenuated virulence of the pathogen to fish could be due to the reduction in ..
  82. Kang D, Kim H. Functional relevance of three proopiomelanocortin (POMC) genes in darkening camouflage, blind-side hypermelanosis, and appetite of Paralichthys olivaceus. Comp Biochem Physiol B Biochem Mol Biol. 2015;179:44-56 pubmed publisher
    ..appetite in flatfish, we isolated and cloned three POMC genes from the pituitary of the olive flounder (Paralichthys olivaceus) and compared their amino acid (aa) structures to those of POMC genes from other animals...
  83. Wang J, Sun L. Edwardsiella tarda-regulated proteins in Japanese flounder (Paralichthys olivaceus): Identification and evaluation of antibacterial potentials. J Proteomics. 2015;124:1-10 pubmed publisher
    ..tarda is a severe aquaculture pathogen that infects a wide range of fish including Japanese flounder (Paralichthys olivaceus)...
  84. Yu H, Si Y, Liu Y, Liu J, Xu X, Zhang Q, et al. Molecular characterization, expression and immune functions of cystatin B in Japanese flounder (Paralichthys olivaceus). Fish Shellfish Immunol. 2018;81:463-469 pubmed publisher
    ..In this study, cystatin B in Japanese flounder (Paralichthys olivaceus) was characterized and its immune function was analyzed...
  85. Dong C, Zhang Y, Lu A, Zhu R, Zhang F, Zhang Q, et al. Molecular characterisation and inductive expression of a fish protein arginine methyltransferase 1 gene in response to virus infection. Fish Shellfish Immunol. 2007;22:380-93 pubmed
    ..Here Paralichthys olivaceus PRMT1 (PoPRMT1) gene was identified as a virally induced gene from UV-inactivated Scophthalmus maximus ..
  86. Kondo H, Yeu Tzeh A, Hirono I, Aoki T. Identification of a novel C-type lectin gene in Japanese flounder, Paralichthys olivaceus. Fish Shellfish Immunol. 2007;23:1089-94 pubmed
    A novel C-type lectin of Japanese flounder (JFCTL) was identified among Japanese flounder liver EST...
  87. Gao J, Li P, Zhang W, Wang Z, Wang X, Zhang Q. Molecular Cloning, Promoter Analysis and Expression Profiles of the sox3 Gene in Japanese Flounder, Paralichthys olivaceus. Int J Mol Sci. 2015;16:27931-44 pubmed publisher
    ..In the present study, Japanese flounder Paralichthys olivaceus sox3 gene (Posox3) and its promoter sequence were isolated and characterized...
  88. Kim S, Nho S, Im S, Lee J, Jung J, Lazarte J, et al. Rapid MALDI biotyper-based identification and cluster analysis of Streptococcus iniae. J Microbiol. 2017;55:260-266 pubmed publisher
    ..iniae causes severe mortalities among cultured marine species, especially in the olive flounder (Paralichthys olivaceus), which is economically important in Korea and Japan...
  89. Dong Y, Zhang X, Tian H, Li X, Wang W, Ru S. Effects of polychlorinated biphenyls on metamorphosis of a marine fish Japanese flounder (Paralichthys olivaceus) in relation to thyroid disruption. Mar Pollut Bull. 2017;119:325-331 pubmed publisher
    ..the influence of environmental concentrations of Aroclor 1254 (10, 100, and 1000ng/L) on metamorphosis of Paralichthys olivaceus, and analyzed the mechanisms in relation to thyroid disruption...
  90. Liu Y, Ma D, Zhao C, Xiao Z, Xu S, Xiao Y, et al. The expression pattern of hsp70 plays a critical role in thermal tolerance of marine demersal fish: Multilevel responses of Paralichthys olivaceus and its hybrids (P. olivaceus ? × P. dentatus ?) to chronic and acute heat stress. Mar Environ Res. 2017;129:386-395 pubmed publisher
    ..This study investigated the different responses of Paralichthys olivaceus and the hybrids (P. olivaceus ? × P. dentatus ?) to chronic and acute heat stress...
  91. Fu Y, Gao L, Shi Z, You F, Zhang J, Li W. Characterization and expression of lin-28a involved in lin28/let-7signal pathway during early development of P. olivaceus. Fish Physiol Biochem. 2018;44:451-463 pubmed publisher
    ..Previous studies showed that ten let-7 miRNAs were identified in the Japanese flounder (Paralichthys olivaceus) and that they were primarily expressed during metamorphosis...
  92. Wang B, Wang H, Gao C, Liu Y, Jin C, Sun M, et al. Functional Analysis of the Promoter Region of Japanese Flounder (Paralichthys olivaceus) ?-actin Gene: A Useful Tool for Gene Research in Marine Fish. Int J Mol Sci. 2018;19: pubmed publisher
    A newly isolated Japanese flounder (Paralichthys olivaceus) &beta;-actin promoter and its derivative compact construct Po&beta;-actin&Delta;&minus;1080/&minus;801&Delta;&minus;500/&minus;201 have ..