southern platyfish


Alias: Xiphophorus maculatus, Platypoecilus maculatus, Platypoecilus maculatus Guenther, 1866, Xiphophorus maculatus (Guenther, 1866)

Top Publications

  1. Volff J, Selz Y, Hoffmann C, Froschauer A, Schultheis C, Schmidt C, et al. Gene amplification and functional diversification of melanocortin 4 receptor at an extremely polymorphic locus controlling sexual maturation in the platyfish. Genetics. 2013;195:1337-52 pubmed publisher
    ..We have analyzed the structure and evolution of the P locus in the platyfish Xiphophorus maculatus, where as many as nine alleles of P determining the onset of sexual maturity in males and females, ..
  2. Poh K, Roslan Z, Misnan R, Sinang S. Characterization and expression of Xiphophorus maculatus microsatellite Msb069 full sequence in subgenus Poecilia. J Genet. 2018;97:817-824 pubmed
    ..However the exact gene expression event of Msb069 is still unknown and requires further investigation. ..
  3. Kawaguchi M, Tomita K, Sano K, Kaneko T. Molecular events in adaptive evolution of the hatching strategy of ovoviviparous fishes. J Exp Zool B Mol Dev Evol. 2015;324:41-50 pubmed publisher
    ..Using genome database of the ovoviviparous platy Xiphophorus maculatus, we tried to search hatching enzyme genes (high choriolytic enzyme HCE and low choriolytic enzyme LCE) and ..
  4. Schartl M, Walter R, Shen Y, Garcia T, Catchen J, Amores A, et al. The genome of the platyfish, Xiphophorus maculatus, provides insights into evolutionary adaptation and several complex traits. Nat Genet. 2013;45:567-72 pubmed publisher
  5. Zhang D, Hu P, Liu T, Wang J, Jiang S, Xu Q, et al. GC bias lead to increased small amino acids and random coils of proteins in cold-water fishes. BMC Genomics. 2018;19:315 pubmed publisher
    ..three tropical fishes, including Danio rerio (zebrafish), Oreochromis niloticus (Nile tilapia) and Xiphophorus maculatus (Platyfish)...
  6. Walter R, Boswell M, Chang J, Boswell W, Lu Y, Navarro K, et al. Waveband specific transcriptional control of select genetic pathways in vertebrate skin (Xiphophorus maculatus). BMC Genomics. 2018;19:355 pubmed publisher
    ..We utilized RNA-Seq to assess changes in the transcriptional profiles of Xiphophorus maculatus skin after exposure to FL ("cool white"), or narrow wavelength regions of light between 350 and 600 nm (i...
  7. Lu Y, Bowswell M, Bowswell W, Yang K, Schartl M, Walter R. Molecular genetic response of Xiphophorus maculatus-X. couchianus interspecies hybrid skin to UVB exposure. Comp Biochem Physiol C Toxicol Pharmacol. 2015;178:86-92 pubmed publisher
  8. Rimmer A, Becker J, Tweedie A, Lintermans M, Landos M, Stephens F, et al. Detection of dwarf gourami iridovirus (Infectious spleen and kidney necrosis virus) in populations of ornamental fish prior to and after importation into Australia, with the first evidence of infection in domestically farmed Platy (Xiphophorus macula. Prev Vet Med. 2015;122:181-94 pubmed publisher
    ..Out of 365 farmed ornamental fish, ISKNV-like megalocytivirus was detected in 1.1%; these were Platy (Xiphophorus maculatus)...
  9. Chang J, Lu Y, Boswell W, Boswell M, Caballero K, Walter R. Molecular genetic response to varied wavelengths of light in Xiphophorus maculatus skin. Comp Biochem Physiol C Toxicol Pharmacol. 2015;178:104-15 pubmed publisher
    ..Herein, we report results of RNA-Seq experiments from the skin of male Xiphophorus maculatus Jp 163 B following exposure to varied 50nm wavelengths of light ranging from 300-600nm...

More Information


  1. Ruymgaart A, Heater S, Oehlers L, Rains J, Walter R. Characterization and purification of flap endonuclease-1 (xiFEN-1) from Xiphophorus maculatus. Zebrafish. 2004;1:273-85 pubmed publisher
    ..xiFEN1 displayed a five-fold greater Km and six-fold lower catalytic efficiency (kcat/Km) than observed for the hFEN1. ..
  2. Cao L, Yin G, Cao Z, Bing X, Ding W. Identification and characterization of a LTR retrotransposon from the genome of Cyprinus carpio var. Jian. Genetica. 2016;144:325-33 pubmed publisher
    ..7, 40, and 32.8 %, to retrotransposons of Azumapecten farreri, Mizuhopecten yessoensis, and Xiphophorus maculatus, respectively. Therefore, JRE might belong to the JULE retrotransposon family...
  3. Pitts P, Volkoff H. Characterization of appetite-regulating factors in platyfish, Xiphophorus maculatus (Cyprinodontiformes Poeciliidae). Comp Biochem Physiol A Mol Integr Physiol. 2017;208:80-88 pubmed publisher
    ..g. orexin and neuropeptide Y (NPY)) peptides. Platyfish, Xiphophorus maculatus, are freshwater viviparous fish for which little is known about the endocrine mechanisms regulating ..
  4. Ahn H, Lee C, Nam B, Kim E, Caetano Anolles K, Kim H. Selective pressure on the protein-coding genes of the pufferfish is correlated with phenotypic traits. Mar Genomics. 2018;37:182-186 pubmed publisher
    ..Gasterosteus aculeatus, Oryzias latipes, Poecilia formosa, Takifugu rubripes, Tetraodon nigroviridis, and Xiphophorus maculatus)...
  5. Oehlers L, Heater S, Rains J, Wells M, David W, Walter R. Gene structure, purification and characterization of DNA polymerase beta from Xiphophorus maculatus. Comp Biochem Physiol C Toxicol Pharmacol. 2004;138:311-24 pubmed
    Cloning of the Xiphophorus maculatus Polbeta gene and overexpression of the recombinant Polbeta protein has been performed...
  6. Veith A, Froschauer A, Körting C, Nanda I, Hanel R, Schmid M, et al. Cloning of the dmrt1 gene of Xiphophorus maculatus: dmY/dmrt1Y is not the master sex-determining gene in the platyfish. Gene. 2003;317:59-66 pubmed
    ..if an orthologue of dmrt1Y was also located in the sex determination region of the related platyfish Xiphophorus maculatus, Southern blot analysis was performed on genomic DNA from XY and YY males and WY and XX females using both ..
  7. Tomaszkiewicz M, Chalopin D, Schartl M, Galiana D, Volff J. A multicopy Y-chromosomal SGNH hydrolase gene expressed in the testis of the platyfish has been captured and mobilized by a Helitron transposon. BMC Genet. 2014;15:44 pubmed publisher
    ..In order to identify genes involved in male sex determination and differentiation in the platyfish Xiphophorus maculatus, bacterial artificial chromosome contigs from the sex-determining region differentiating the Y from the X ..
  8. Walter R, Obermoeller R, Moore D, Lacson J, Della Coletta L, McEntire B, et al. Characterization and mapping of the Xiphophorus maculatus (Teleostei: Poeciliidae) RPS15 gene. Cytogenet Cell Genet. 1996;75:140-4 pubmed
    We have determined the nucleotide sequence and gene map location of the Xiphophorus maculatus homologue of RPS15 (ribosomal protein S15, alias RIG)...
  9. Rock R, Heinrich A, Schumacher N, Gessler M. Fjx1: a notch-inducible secreted ligand with specific binding sites in developing mouse embryos and adult brain. Dev Dyn. 2005;234:602-12 pubmed publisher
    ..Through the use of an fjx1-AP fusion protein, we could visualize fjx1 binding sites at complementary locations, supporting the notion that fjx1 may function as a novel signaling molecule...
  10. Yamashita M, Hirayoshi K, Nagata K. Characterization of multiple members of the HSP70 family in platyfish culture cells: molecular evolution of stress protein HSP70 in vertebrates. Gene. 2004;336:207-18 pubmed publisher
  11. G tz R, Raulf F, Schartl M. Brain-derived neurotrophic factor is more highly conserved in structure and function than nerve growth factor during vertebrate evolution. J Neurochem. 1992;59:432-42 pubmed
    ..By RNA gel blot analysis NGF mRNA was detected during late embryonic development; BDNF was present in adult brain...
  12. Kazianis S, Gan L, Della Coletta L, Santi B, Morizot D, Nairn R. Cloning and comparative sequence analysis of TP53 in Xiphophorus fish hybrid melanoma models. Gene. 1998;212:31-8 pubmed
    We have cloned and sequenced the p53-encoding cDNA of green swordtail (X. helleri) and southern platyfish (X. maculatus). These two fish species are often used to produce hybrids that develop melanomas after genetic crossing...
  13. Bao S, Nie X, Liu Y, Wang C, Li W, Liu S. Diclofenac exposure alter the expression of PXR and its downstream target genes in mosquito fish (Gambusia affinis). Sci Total Environ. 2018;616-617:583-593 pubmed publisher
    ..affinis and other killifish species, such as Xiphophorus maculatus. The transcriptional expression of these genes mentioned above and partly related enzymes/proteins ..
  14. Boswell W, Boswell M, Walter D, Navarro K, Chang J, Lu Y, et al. Exposure to 4100K fluorescent light elicits sex specific transcriptional responses in Xiphophorus maculatus skin. Comp Biochem Physiol C Toxicol Pharmacol. 2018;208:96-104 pubmed publisher
    ..In addition, we identify clusters of genes that become oppositely modulated in males and females after FL exposure that are principally involved in cell death and cell proliferation. ..
  15. Gonzalez T, Lu Y, Boswell M, Boswell W, Medrano G, Walter S, et al. Fluorescent light exposure incites acute and prolonged immune responses in zebrafish (Danio rerio) skin. Comp Biochem Physiol C Toxicol Pharmacol. 2018;208:87-95 pubmed publisher
    ..rhythm, cell cycle progression, chromosome segregation, and DNA repair/recombination in the skin of male Xiphophorus maculatus. These observations raise questions concerning the kinetics of the FL induced gene expression response, ..
  16. Woolcock B, Schmidt B, Kallman K, Vielkind J. Differences in transcription and promoters of Xmrk-1 and Xmrk-2 genes suggest a role for Xmrk-2 in pigment pattern development in the platyfish, Xiphophorus maculatus. Cell Growth Differ. 1994;5:575-83 pubmed
    Pigment (macromelanophore) patterns in the platyfish Xiphophorus maculatus are due to a complex pigmentary locus; for example, the spotted-dorsal (Sd) fin pattern is due to the Sd locus...
  17. Lu Y, Reyes J, Walter S, Gonzalez T, Medrano G, Boswell M, et al. Characterization of basal gene expression trends over a diurnal cycle in Xiphophorus maculatus skin, brain and liver. Comp Biochem Physiol C Toxicol Pharmacol. 2018;208:2-11 pubmed publisher
    ..In addition, we were able to categorize light responsive gene sets in Xiphophorus that do, and do not, exhibit circadian based oscillating expression patterns. ..
  18. G tz R, K ster R, Winkler C, Raulf F, Lottspeich F, Schartl M, et al. Neurotrophin-6 is a new member of the nerve growth factor family. Nature. 1994;372:266-9 pubmed publisher
    ..NT-6 is expressed in the embryonic valvulla cerebelli; expression persists in some adult tissues. The interaction of NT-6 with heparin-binding molecules may modulate its action in the nervous system...
  19. McConnell T, Godwin U, Norton S, Nairn R, Kazianis S, Morizot D. Identification and mapping of two divergent, unlinked major histocompatibility complex class II B genes in Xiphophorus fishes. Genetics. 1998;149:1921-34 pubmed
    We have isolated two major histocompatibility complex (MHC) class II B genes from the inbred fish strain Xiphophorus maculatus Jp 163 A...
  20. B hne A, Zhou Q, Darras A, Schmidt C, Schartl M, Galiana Arnoux D, et al. Zisupton--a novel superfamily of DNA transposable elements recently active in fish. Mol Biol Evol. 2012;29:631-45 pubmed publisher
    ..We have identified a new superfamily of DNA transposon on the Y chromosome of the platyfish Xiphophorus maculatus. This element is 11 kb in length and carries a single CDS of 24 exons...
  21. B hne A, Darras A, D Cotta H, Baroiller J, Galiana Arnoux D, Volff J. The vertebrate makorin ubiquitin ligase gene family has been shaped by large-scale duplication and retroposition from an ancestral gonad-specific, maternal-effect gene. BMC Genomics. 2010;11:721 pubmed publisher
    ..Via partial sequencing of a testis cDNA library from the poeciliid fish Xiphophorus maculatus, we have identified a new member of the makorin gene family, that we called mkrn4...
  22. Veith A, Sch fer M, Kl ver N, Schmidt C, Schultheis C, Schartl M, et al. Tissue-specific expression of dmrt genes in embryos and adults of the platyfish Xiphophorus maculatus. Zebrafish. 2006;3:325-37 pubmed publisher
    ..The cloning of dmrt5 from the platyfish Xiphophorus maculatus and the expression pattern of dmrt1, dmrt2a, dmrt4, and dmrt5 in adults and embryos are reported...
  23. Selz Y, Braasch I, Hoffmann C, Schmidt C, Schultheis C, Schartl M, et al. Evolution of melanocortin receptors in teleost fish: the melanocortin type 1 receptor. Gene. 2007;401:114-22 pubmed publisher
    ..mc1r from three major fish models, the zebrafish Danio rerio, the medaka Oryzias latipes and the platyfish Xiphophorus maculatus. In contrast to some other melanocortin receptor genes, mc1r has been conserved as a single copy gene in ..
  24. Rudd M, Johnston D, Kazianis S, Butler A. Cloning and analysis of a FoxO transcription factor from Xiphophorus. Gene. 2003;302:31-41 pubmed
    ..Towards this end, we have cloned an FKHR (FoxO sub-family) homolog from Xiphophorus maculatus. The isolated clone is a 2.7 kb cDNA encoding a predicted protein of 664 amino acids...
  25. Merritt T, Quattro J. Evidence for a period of directional selection following gene duplication in a neurally expressed locus of triosephosphate isomerase. Genetics. 2001;159:689-97 pubmed
    ..Further, the number of nucleotide changes required for the observed amino acid substitutions suggests that selection acted on the overall charge of the protein and not on specific key amino acids...
  26. Butler A, Trono D, Coletta L, Beard R, Fraijo R, Kazianis S, et al. Regulation of CDKN2A/B and Retinoblastoma genes in Xiphophorus melanoma. Comp Biochem Physiol C Toxicol Pharmacol. 2007;145:145-55 pubmed publisher
    ..human tumors, and is capable of transcriptionally regulating RB in human ovarian tumors, we cloned the Xiphophorus maculatus RB cDNA and analyzed RB expression by real-time PCR and Western blot analysis in the fish melanomas...
  27. Castro J, Horn D, Pu X, Lewis K. Recombinant expression and purification of the RNA-binding LARP6 proteins from fish genetic model organisms. Protein Expr Purif. 2017;134:147-153 pubmed publisher
    ..we have recombinantly expressed the full-length LARP6 proteins from two teleost fish, platyfish (Xiphophorus maculatus) and zebrafish (Danio rerio)...
  28. Boswell M, Boswell W, Lu Y, Savage M, Mazurek Z, Chang J, et al. The transcriptional response of skin to fluorescent light exposure in viviparous (Xiphophorus) and oviparous (Danio, Oryzias) fishes. Comp Biochem Physiol C Toxicol Pharmacol. 2018;208:77-86 pubmed publisher
    ..transcriptomes has been tested in three aquatic animal models commonly utilized in biomedical research, (Xiphophorus maculatus (platyfish), Oryzias latipes (medaka) and Danio rerio (zebrafish)...