killifish

Summary

Alias: Atlantic killifish, mummichog, Fundulus heteroclitus, Fundulus heteroclitus (Linnaeus, 1766)

Top Publications

  1. Hahn M, Karchner S, Franks D, Merson R. Aryl hydrocarbon receptor polymorphisms and dioxin resistance in Atlantic killifish (Fundulus heteroclitus). Pharmacogenetics. 2004;14:131-43 pubmed
    ..in differential sensitivity to HAHs and PAHs, we are currently studying a population of the teleost Fundulus heteroclitus (Atlantic killifish) that has evolved genetic resistance to the toxic and biochemical effects of these ..
  2. Notch E, Chapline C, Flynn E, Lameyer T, Lowell A, SATO D, et al. Mitogen activated protein kinase 14-1 regulates serum glucocorticoid kinase 1 during seawater acclimation in Atlantic killifish, Fundulus heteroclitus. Comp Biochem Physiol A Mol Integr Physiol. 2012;162:443-8 pubmed publisher
    The Atlantic killifish (Fundulus heteroclitus) is an environmental sentinel organism used extensively for studies of environmental toxicants and osmoregulation...
  3. Guan Y, Zhang G, Zhang S, Domangue B, Galvez F. The potential role of polyamines in gill epithelial remodeling during extreme hypoosmotic challenges in the Gulf killifish, Fundulus grandis. Comp Biochem Physiol B Biochem Mol Biol. 2016;194-195:39-50 pubmed publisher
    ..These data suggest polyamines blunt the hypotonic inhibition of NaCl secretion and may lead to early apoptosis of seawater ionocytes and their replacement by FW-type ionocytes. ..
  4. Larter K, Rees B. Influence of euthanasia method on blood and gill variables in normoxic and hypoxic Gulf killifish Fundulus grandis. J Fish Biol. 2017;90:2323-2343 pubmed publisher
    ..glucose) or reflecting gill damage (trypan blue exclusion) and energetic status (ATP, ADP and ATP:ADP) in Gulf killifish Fundulus grandis after 24?h exposure to well-aerated conditions (normoxia, 7·93?mg?O2 ?l-1..
  5. Oziolor E, Howard W, Lavado R, Matson C. Induced pesticide tolerance results from detoxification pathway priming. Environ Pollut. 2017;224:615-621 pubmed publisher
    ..Here, we used Gulf killifish (Fundulus grandis) to test the role of detoxification pathway priming in this inducible tolerance...
  6. Finch B, Marzooghi S, Di Toro D, Stubblefield W. Phototoxic potential of undispersed and dispersed fresh and weathered Macondo crude oils to Gulf of Mexico Marine Organisms. Environ Toxicol Chem. 2017;36:2640-2650 pubmed publisher
    ..Americamysis bahia), inland silverside (Menidia beryllina), sheepshead minnow (Cyprinodon variegatus), and Gulf killifish (Fundulus grandis)...
  7. Le Y, Shen X, Kang H, Wang Q, Li K, Zheng J, et al. Accelerated untargeted metabolomics analysis of cutaneous T-cell lymphoma reveal metabolic shifts in plasma and tumor adjacent skins of xenograft mice. J Mass Spectrom. 2017;: pubmed publisher
    ..aims to explore the metabolic profiling of CTCL by an accelerated untargeted metabolomics data analysis tool "mummichog" to facilitate the discoveries of potential biomarkers for clinical early-stage diagnosis, prognosis and ..
  8. Robertson L, Val A, Almeida Val V, Wood C. Ionoregulatory Aspects of the Osmorespiratory Compromise during Acute Environmental Hypoxia in 12 Tropical and Temperate Teleosts. Physiol Biochem Zool. 2015;88:357-70 pubmed publisher
    ..tetra (Hemigrammus rhodostomus), the pumpkinseed sunfish (Lepomis gibbosus), and the Atlantic killifish (Fundulus heteroclitus)...
  9. Dubansky B, Rice C, Barrois L, Galvez F. Biomarkers of Aryl-hydrocarbon Receptor Activity in Gulf Killifish (Fundulus grandis) From Northern Gulf of Mexico Marshes Following the Deepwater Horizon Oil Spill. Arch Environ Contam Toxicol. 2017;73:63-75 pubmed publisher
    ..The Gulf killifish (Fundulus grandis) has been identified as a sentinel species for the study of site-specific effects of crude oil ..

More Information

Publications171 found, 100 shown here

  1. Finch B, Stubblefield W. Photo-enhanced toxicity of fluoranthene to Gulf of Mexico marine organisms at different larval ages and ultraviolet light intensities. Environ Toxicol Chem. 2016;35:1113-22 pubmed publisher
    ..Americamysis bahia), inland silverside (Menidia beryllina), sheepshead minnow (Cyprinodon variegatus), and Gulf killifish (Fundulus grandis) to photo-enhanced toxicity and to examine the correlation between photo-enhanced toxicity and ..
  2. Oziolor E, Carey A, Matson C. A non-destructive BFCOD assay for in vivo measurement of cytochrome P450 3A (CYP3A) enzyme activity in fish embryos and larvae. Ecotoxicology. 2017;26:809-819 pubmed publisher
    ..a rapid and inexpensive method to measure in vivo (and in ovo) CYP3A activity in two fish systems: Gulf killifish (Fundulus grandis) and zebrafish (Danio rerio) early life stages...
  3. Bao S, Nie X, Liu Y, Wang C, Li W, Liu S. Diclofenac exposure alter the expression of PXR and its downstream target genes in mosquito fish (Gambusia affinis). Sci Total Environ. 2018;616-617:583-593 pubmed publisher
    ..Phylogenetic trees and blast results showed a high similarity between G. affinis and other killifish species, such as Xiphophorus maculatus...
  4. Moravec F, de Buron I, González Solís D. Redescription of three species of nematodes (Nematoda) parasitising fishes in the USA, with a key to the species of Dichelyne Jägerskiöld, 1902 parasitic in freshwater and brackish-water fishes of North America. Syst Parasitol. 2019;96:79-94 pubmed publisher
    ..in fishes of South Carolina, USA: Dichelyne (Cucullanellus) bullocki Stromberg & Crites, 1972 from Fundulus heteroclitus (Linnaeus) (Fundulidae); Dichelyne (Dichelyne) diplocaecum Chandler, 1935 from Ictalurus furcatus (..
  5. Subramaniam J, Murugan K, Panneerselvam C, Kovendan K, Madhiyazhagan P, Dinesh D, et al. Multipurpose effectiveness of Couroupita guianensis-synthesized gold nanoparticles: high antiplasmodial potential, field efficacy against malaria vectors and synergy with Aplocheilus lineatus predators. Environ Sci Pollut Res Int. 2016;23:7543-58 pubmed publisher
    ..In standard laboratory conditions, the predation efficiency of golden wonder killifish, Aplocheilus lineatus, against A. stephensi IV instar larvae was 56...
  6. Reid N, Proestou D, Clark B, Warren W, Colbourne J, Shaw J, et al. The genomic landscape of rapid repeated evolutionary adaptation to toxic pollution in wild fish. Science. 2016;354:1305-1308 pubmed
    b>Atlantic killifish populations have rapidly adapted to normally lethal levels of pollution in four urban estuaries...
  7. Wagner J, Singh P, Romney A, Riggs C, Minx P, Woll S, et al. The genome of Austrofundulus limnaeus offers insights into extreme vertebrate stress tolerance and embryonic development. BMC Genomics. 2018;19:155 pubmed publisher
    The annual killifish Austrofundulus limnaeus inhabits ephemeral ponds in northern Venezuela, South America, and is an emerging extremophile model for vertebrate diapause, stress tolerance, and evolution. Embryos of A...
  8. Maynard C, Weinkove D. The Gut Microbiota and Ageing. Subcell Biochem. 2018;90:351-371 pubmed publisher
    ..Antibiotics also extend the lifespan of middle-aged killifish but additional transplantation of gut microbes from young killifish extends lifespan further, suggesting a ..
  9. Davis J, Ekman D, Skelton D, LaLone C, Ankley G, Cavallin J, et al. Metabolomics for informing adverse outcome pathways: Androgen receptor activation and the pharmaceutical spironolactone. Aquat Toxicol. 2017;184:103-115 pubmed publisher
    ..g., methionine) and VTG (e.g., glutamate). Based on a network analysis program (i.e., mummichog), spironolactone also affected amino acid, tryptophan, and fatty acid metabolism...
  10. Marshall W, Cozzi R, Spieker M. WNK1 and p38-MAPK distribution in ionocytes and accessory cells of euryhaline teleost fish implies ionoregulatory function. Biol Open. 2017;6:956-966 pubmed publisher
    ..Mummichogs (Fundulus heteroclitus L.) were acclimated to freshwater (FW), full strength seawater (SW) and hypersaline conditions (2SW)...
  11. Amodeo P, D Aniello E, Defranoux F, Marino A, D angelo L, Ghiselin M, et al. The Suitability of Fishes as Models for Studying Appetitive Behavior in Vertebrates. Results Probl Cell Differ. 2018;65:423-438 pubmed publisher
    ..help to ensure greater translatability of the fish models, such as the zebrafish (Danio rerio), the turquoise killifish (Nothobranchius furzeri), the goldfish (Carassius auratus), or the Japanese medaka fish (Oryzias latipes) to ..
  12. Puthumana J, Kim B, Jeong C, Kim D, Kang H, Jung J, et al. Nine co-localized cytochrome P450 genes of the CYP2N, CYP2AD, and CYP2P gene families in the mangrove killifish Kryptolebias marmoratus genome: Identification and expression in response to B[?]P, BPA, OP, and NP. Aquat Toxicol. 2017;187:132-140 pubmed publisher
    ..In this paper, we identify and characterize a CYP2 gene cluster in the mangrove killifish K. marmoratus with differing catalytic roles toward EDCs...
  13. Toni L, Padilla P. Developmentally arrested Austrofundulus limnaeus embryos have changes in post-translational modifications of histone H3. J Exp Biol. 2016;219:544-52 pubmed publisher
    ..The embryos of Austrofundulus limnaeus, a killifish that resides in ephemeral ponds, routinely enter diapause II (DII), a reversible developmental arrest promoted ..
  14. Zupkovitz G, Lagger S, Martin D, Steiner M, Hagelkruys A, Seiser C, et al. Histone deacetylase 1 expression is inversely correlated with age in the short-lived fish Nothobranchius furzeri. Histochem Cell Biol. 2018;150:255-269 pubmed publisher
    ..However, no hdac2 ortholog could be identified. Phylogenetic analysis grouped the individual killifish class I Hdacs within the well-defined terminal clades...
  15. Leonardi M, Vera J, Tarifeño E, Puchi M, Morín V. Vitellogenin of the Chilean flounder Paralichthys adspersus as a biomarker of endocrine disruption along the marine coast of the South Pacific. Part I: induction, purification, and identification. Fish Physiol Biochem. 2010;36:757-765 pubmed publisher
    ..of vitellogenin (VgI, VgII, Vg A and Vg B) in Chilean flounder, similar to species such as mummichog (Fundulus heteroclitus), Japanese medaka (Oryzias latipes), and white perch (Morone americana)...
  16. Bomberger J, Coutermarsh B, Barnaby R, Stanton B. Arsenic promotes ubiquitinylation and lysosomal degradation of cystic fibrosis transmembrane conductance regulator (CFTR) chloride channels in human airway epithelial cells. J Biol Chem. 2012;287:17130-9 pubmed publisher
    ..Recently, we observed in the gill of killifish, an environmental model organism, that arsenic exposure induced the ubiquitinylation and degradation of cystic ..
  17. Kang H, Lee Y, Kim B, Kim I, Jeong C, Lee J. Adverse effects of BDE-47 on in vivo developmental parameters, thyroid hormones, and expression of hypothalamus-pituitary-thyroid (HPT) axis genes in larvae of the self-fertilizing fish Kryptolebias marmoratus. Chemosphere. 2017;176:39-46 pubmed publisher
    ..and an imbalance in thyroid hormone (TH) homeostasis was shown in the early developmental stages of the mangrove killifish Kryptolebias marmoratus in response to BDE-47 exposure...
  18. Metzger D, Hemmer Hansen J, Schulte P. Conserved structure and expression of hsp70 paralogs in teleost fishes. Comp Biochem Physiol Part D Genomics Proteomics. 2016;18:10-20 pubmed publisher
    ..these represent poorly assembled tandem duplicates, we cloned the genomic region surrounding hsp70-2 in Fundulus heteroclitus and showed that the hsp70-2 gene copies that are on separate scaffolds in the genome assembly are arranged ..
  19. Pamungkas A, Medriano C, Sim E, Lee S, Park Y. A pilot study identifying a potential plasma biomarker for determining EGFR mutations in exons 19 or 21 in lung cancer patients. Mol Med Rep. 2017;15:4155-4161 pubmed publisher
    ..Furthermore, the significant metabolites were identified and mapped using Mummichog software, in order to generate a potential metabolic network model...
  20. Redelings B, Kumagai S, Tatarenkov A, Wang L, Sakai A, Weller S, et al. A Bayesian Approach to Inferring Rates of Selfing and Locus-Specific Mutation. Genetics. 2015;201:1171-88 pubmed publisher
    ..reproduction under pure hermaphroditism, gynodioecy, and a model developed to describe the self-fertilizing killifish Kryptolebias marmoratus...
  21. Lee Y, Khan A, Hong S, Jee S, Park Y. A metabolomic study on high-risk stroke patients determines low levels of serum lysine metabolites: a retrospective cohort study. Mol Biosyst. 2017;13:1109-1120 pubmed publisher
    ..Mapping identified features from Kyoto Encyclopedia of Genes and Genomes (KEGG) and Mummichog resulted in 341 significant features based on OPLS-DA with p-value <0.05...
  22. Heid J, Cencioni C, Ripa R, Baumgart M, Atlante S, Milano G, et al. Age-dependent increase of oxidative stress regulates microRNA-29 family preserving cardiac health. Sci Rep. 2017;7:16839 pubmed publisher
    The short-lived turquoise killifish Nothobranchius furzeri (Nfu) is a valid model for aging studies. Here, we investigated its age-associated cardiac function...
  23. Novais F, Pires P, Alexandre P, Dromms R, Iglesias A, Ferraz J, et al. Identification of a metabolomic signature associated with feed efficiency in beef cattle. BMC Genomics. 2019;20:8 pubmed publisher
    ..55, P < 0.05). Pathway enrichment analysis (Mummichog) yielded the Retinol metabolism pathway associated with feed efficiency in beef cattle in our conditions...
  24. Livingston M, Bhargav V, Turko A, Wilson J, Wright P. Widespread use of emersion and cutaneous ammonia excretion in Aplocheiloid killifishes. Proc Biol Sci. 2018;285: pubmed publisher
    ..Overall, our results demonstrate that similar nitrogen excretion strategies while out of water were used by all killifish species tested; possibly the result of shared ancestral amphibious traits, phenotypic convergence, or a ..
  25. Kopec A, Kidd K, Fisher N, Bowen M, Francis C, Payne K, et al. Spatial and temporal trends of mercury in the aquatic food web of the lower Penobscot River, Maine, USA, affected by a chlor-alkali plant. Sci Total Environ. 2019;649:770-791 pubmed publisher
    ..size or age) in the most affected areas were 521 (480, 566; 95% CI) ng/g ww in American eels, 321 (261,395) in mummichog, 121 (104, 140) in rainbow smelt, 155 (142,169) in tomcod, 55.2 (42.7,71...
  26. Araya Jaime C, Lam N, Pinto I, Mendez M, Iturra P. Chromosomal organization of four classes of repetitive DNA sequences in killifish Orestias ascotanensis Parenti, 1984 (Cyprinodontiformes, Cyprinodontidae). Comp Cytogenet. 2017;11:463-475 pubmed publisher
    ..These data will improve our understanding of the chromosomal evolution of a genus facing serious conservation problems...
  27. Jin R, Banton S, Tran V, Konomi J, Li S, Jones D, et al. Amino Acid Metabolism is Altered in Adolescents with Nonalcoholic Fatty Liver Disease-An Untargeted, High Resolution Metabolomics Study. J Pediatr. 2016;172:14-19.e5 pubmed publisher
    ..Untargeted pathway analyses using Mummichog were performed among the significant metabolites to identify pathways that were most dysregulated in NAFLD...
  28. Vlaanderen J, Janssen N, Hoek G, Keski Rahkonen P, Barupal D, Cassee F, et al. The impact of ambient air pollution on the human blood metabolome. Environ Res. 2017;156:341-348 pubmed publisher
    ..Bioinformatics approach Mummichog predicted enriched pathway activity in eight pathways, among which tyrosine metabolism...
  29. D angelo L, Lossi L, Merighi A, De Girolamo P. Anatomical features for the adequate choice of experimental animal models in biomedicine: I. Fishes. Ann Anat. 2016;205:75-84 pubmed publisher
    ..consideration when selecting an animal model: zebrafish (Danio rerio), medaka (Oryzias latypes), the turquoise killifish (Nothobranchius furzeri), and goldfish (Carassius auratus)...
  30. Thompson A, Orti G. Annual Killifish Transcriptomics and Candidate Genes for Metazoan Diapause. Mol Biol Evol. 2016;33:2391-5 pubmed publisher
    ..We report the diapause transcriptome of the annual killifish Nematolebias whitei, and compare gene expression between diapause embryos and free-living larvae to identify a ..
  31. Cozzi R, Robertson G, Spieker M, Claus L, Zaparilla G, Garrow K, et al. Paracellular pathway remodeling enhances sodium secretion by teleost fish in hypersaline environments. J Exp Biol. 2015;218:1259-69 pubmed publisher
    ..Mummichogs (Fundulus heteroclitus) acclimated to hypersaline [2× seawater (2SW), 64‰] for 30 days developed invasive ..
  32. Baris T, Wagner D, Dayan D, Du X, Blier P, Pichaud N, et al. Evolved genetic and phenotypic differences due to mitochondrial-nuclear interactions. PLoS Genet. 2017;13:e1006517 pubmed publisher
    ..mito-nuclear interactions alter allele frequencies for ~11,000 nuclear SNPs within a single, natural Fundulus heteroclitus population containing two divergent mitochondrial haplotypes (mt-haplotypes)...
  33. Freyhof J, Weissenbacher A, Geiger M. <i>Aphanius</i> <i>kruppi</i>, a new killifish from Oman with comments on the<i> A. dispar</i> species group (Cyprinodontiformes: Aphaniidae). Zootaxa. 2017;4338:557-573 pubmed publisher
    ..The available molecular genetic data for A. dispar reject the hypothesis of the presence of a single widespread coastal species in the Middle East and make it likely that two additional unidentified species occur in the Red Sea basin. ..
  34. Tebani A, Schmitz Afonso I, Abily Donval L, Heron B, Piraud M, Ausseil J, et al. Urinary metabolic phenotyping of mucopolysaccharidosis type I combining untargeted and targeted strategies with data modeling. Clin Chim Acta. 2017;475:7-14 pubmed publisher
    ..Univariate and multivariate data analyses have been used to select discriminant metabolites. The mummichog algorithm has been used for pathway analysis...
  35. Vrtílek M, Žák J, Polačik M, Blažek R, Reichard M. Longitudinal demographic study of wild populations of African annual killifish. Sci Rep. 2018;8:4774 pubmed publisher
    ..address this gap, we present lifetime demographic data from wild populations of an annual species, the turquoise killifish, Nothobranchius furzeri, a model species in ageing research, and two other species of coexisting annual ..
  36. Brennan R, Galvez F, Whitehead A. Reciprocal osmotic challenges reveal mechanisms of divergence in phenotypic plasticity in the killifish Fundulus heteroclitus. J Exp Biol. 2015;218:1212-22 pubmed publisher
    The killifish Fundulus heteroclitus is an estuarine species with broad physiological plasticity, enabling acclimation to diverse stressors...
  37. Pérez Ponce de León G, Pinacho Pinacho C, Mendoza Garfias B, García Varela M. Phyllodistomum spinopapillatum sp. nov. (Digenea: Gorgoderidae), from the Oaxaca killifish Profundulus balsanus (Osteichthyes: Profundulidae) in Mexico, with new host and locality records of P. inecoli: Morphology, ultrastructure and molecular eviden. Acta Parasitol. 2015;60:298-307 pubmed publisher
    Phyllodistomum spinopapillatum sp. nov. is described from the urinary bladder of the Oaxaca killifish, Profundulus balsanus Ahl (Profundulidae) in Rio Pueblo Viejo and Rio Santa Cruz, Oaxaca, southwestern Mexico...
  38. Cotter K, Nacci D, Champlin D, Yeo A, Gilmore T, Callard G. Adaptive Significance of ER? Splice Variants in Killifish (Fundulus heteroclitus) Resident in an Estrogenic Environment. Endocrinology. 2016;157:2294-308 pubmed publisher
    ..Embryos/larvae of killifish from an estrogenic-polluted environment (New Bedford Harbor, MA [NBH]) compared with those from a reference site ..
  39. Lucon Xiccato T, Mazzoldi C, Griggio M. Sex composition modulates the effects of familiarity in new environment. Behav Processes. 2017;140:133-138 pubmed publisher
    ..the exploratory behaviour of groups of two females, two males, and one male and one female Mediterranean killifish, Aphanius fasciatus, which were either familiar or unfamiliar...
  40. Gumerova N, Krivosudský L, Fraqueza G, Breibeck J, Al Sayed E, Tanuhadi E, et al. The P-type ATPase inhibiting potential of polyoxotungstates. Metallomics. 2018;10:287-295 pubmed publisher
    ..activity, for the first time an ex vivo study was conducted using the opercular epithelium of killifish in order to investigate the effects of POTs on the epithelial chloride secretion...
  41. Katwate U, Kumkar P, Britz R, Raghavan R, Dahanukar N. The identity of Aplocheilus andamanicus (Köhler, 1906) (Teleostei: Cyprinodontiformes), an endemic Killifish from the Andaman Islands, with notes on Odontopsis armata van Hasselt. Zootaxa. 2018;4382:159-174 pubmed publisher
    ..panchax. While resolving the identity of A. andamanicus, we also demonstrate that the congeners from southeast Asia form a genetically distinct group for which the name Odontopsis armata is available. ..
  42. He P, Matich E, Yonkos L, Friedman A, Atilla Gokcumen G, Aga D. Mass spectrometry based detection of common vitellogenin peptides across fish species for assessing exposure to estrogenic compounds in aquatic environments. Sci Total Environ. 2019;646:400-408 pubmed publisher
    ..VTG protein isolated from three different fish species (Pimephales promelas, Micropterus salmoides, and Fundulus heteroclitus)...
  43. Abbaraju N, Boutaghou M, Townley I, Zhang Q, Wang G, Cole R, et al. Analysis of tissue proteomes of the Gulf killifish, Fundulus grandis, by 2D electrophoresis and MALDI-TOF/TOF mass spectrometry. Integr Comp Biol. 2012;52:626-35 pubmed publisher
    The Gulf killifish, Fundulus grandis, is a small teleost fish that inhabits marshes of the Gulf of Mexico and demonstrates high tolerance of environmental variation, making it an excellent subject for the study of physiological and ..
  44. Ransberry V, Morash A, Blewett T, Wood C, McClelland G. Oxidative stress and metabolic responses to copper in freshwater- and seawater-acclimated killifish, Fundulus heteroclitus. Aquat Toxicol. 2015;161:242-52 pubmed publisher
    ..the effects of salinity on Cu-induced oxidative stress and metabolic responses in adult killifish, Fundulus heteroclitus. We exposed FW and SW-acclimated killifish to either low Cu (LC, 50 μg/L) or high Cu (HC, 200 μg/L) ..
  45. Du X, Crawford D, Oleksiak M. Effects of Anthropogenic Pollution on the Oxidative Phosphorylation Pathway of Hepatocytes from Natural Populations of Fundulus heteroclitus. Aquat Toxicol. 2015;165:231-40 pubmed publisher
    ..by measuring oxidative phosphorylation (OxPhos) metabolism in hepatocytes isolated from lab-depurated Fundulus heteroclitus from a Superfund site contaminated with PAHs (Elizabeth River VA, USA) relative to OxPhos metabolism in ..
  46. Brown D, Bailey J, Oliveri A, Levin E, Di Giulio R. Developmental exposure to a complex PAH mixture causes persistent behavioral effects in naive Fundulus heteroclitus (killifish) but not in a population of PAH-adapted killifish. Neurotoxicol Teratol. 2016;53:55-63 pubmed publisher
    ..the long-term behavioral consequences of subteratogenic developmental PAH mixture exposure in both naive killifish and PAH-adapted killifish using sediment pore water derived from the Atlantic Wood Industries Superfund Site...
  47. Valenzano D, Benayoun B, Singh P, Zhang E, Etter P, Hu C, et al. The African Turquoise Killifish Genome Provides Insights into Evolution and Genetic Architecture of Lifespan. Cell. 2015;163:1539-54 pubmed publisher
    ..Here we de novo assemble a reference genome for the naturally short-lived African turquoise killifish, providing a unique resource for comparative and experimental genomics...
  48. Brix K, Brauner C, Schluter D, Wood C. Pharmacological evidence that DAPI inhibits NHE2 in Fundulus heteroclitus acclimated to freshwater. Comp Biochem Physiol C Toxicol Pharmacol. 2018;211:1-6 pubmed publisher
    Ionoregulation in the euryhaline killifish Fundulus heteroclitus has been intensively studied over the last two decades using a variety of techniques...
  49. Lawrence DeKoning A, Picard D, Bond S, Schulte P. Stress and interpopulation variation in glycolytic enzyme activity and expression in a teleost fish Fundulus heteroclitus. Physiol Biochem Zool. 2004;77:18-26 pubmed
    Northern populations of Fundulus heteroclitus have twofold greater activity of lactate dehydrogenase-B (LDH-B) than southern populations, but exposure to stress increases LDH-B in southern populations, abolishing this difference...
  50. Cotter K, Nacci D, Champlin D, Chuprin J, Callard G. Cloning of multiple ERα mRNA variants in killifish (Fundulus heteroclitus), and differential expression by tissue type, stage of reproduction, and estrogen exposure in fish from polluted and unpolluted environments. Aquat Toxicol. 2015;159:184-97 pubmed publisher
    ..exposures, we compared estrogen receptor alpha (ERα) splicing variants in two populations of killifish (Fundulus heteroclitus): one resident in an estrogenic polluted environment (New Bedford Harbor, NBH, MA, USA) and one from a ..
  51. Altner M, Reichenbacher B. †Kenyaichthyidae fam. nov. and †Kenyaichthys gen. nov. - First Record of a Fossil Aplocheiloid Killifish (Teleostei, Cyprinodontiformes). PLoS ONE. 2015;10:e0123056 pubmed publisher
    ..the Tugen Hills of the Central Rift Valley of Kenya, which represent the first fossil record of an aplocheiloid killifish. A total of 169 specimens - mostly extraordinarily well preserved - and a sample of ten extant cyprinodontiform ..
  52. Ma S, Gladyshev V. Molecular signatures of longevity: Insights from cross-species comparative studies. Semin Cell Dev Biol. 2017;70:190-203 pubmed publisher
    ..include genome sequencing of microbats, naked mole rat, blind mole rat, bowhead whale and African turquoise killifish, and comparative analyses of gene expression, metabolites, lipids and ions across multiple mammalian species...
  53. Rutherford R, Lister A, Hewitt L, Maclatchy D. Effects of model aromatizable (17α-methyltestosterone) and non-aromatizable (5α-dihydrotestosterone) androgens on the adult mummichog (Fundulus heteroclitus) in a short-term reproductive endocrine bioassay. Comp Biochem Physiol C Toxicol Pharmacol. 2015;170:8-18 pubmed publisher
    ..reproductive endocrine status in fish in estuarine environments, male and female adult northern mummichog (Fundulus heteroclitus macrolepidotus) were exposed to an aromatizable androgen (17α-methyltestosterone; MT) and a non-..
  54. Tatarenkov A, Ring B, Elder J, Bechler D, Avise J. Genetic composition of laboratory stocks of the self-fertilizing fish Kryptolebias marmoratus: a valuable resource for experimental research. PLoS ONE. 2010;5:e12863 pubmed publisher
    The hermaphroditic Mangrove Killifish, Kryptolebias marmoratus, is the world's only vertebrate that routinely self-fertilizes...
  55. Renick V, Weinersmith K, Vidal Dorsch D, Anderson T. Effects of a pesticide and a parasite on neurological, endocrine, and behavioral responses of an estuarine fish. Aquat Toxicol. 2016;170:335-343 pubmed publisher
    ..chlorpyrifos and the trematode parasite Euhaplorchis californiensis on three important traits of California killifish (Fundulus parvipinnis): neurotransmitter activity, release of the stress hormone cortisol, and behavior...
  56. Wojdylo J, Vogelbein W, Bain L, Rice C. AHR-related activities in a creosote-adapted population of adult atlantic killifish, Fundulus heteroclitus, two decades post-EPA superfund status at the Atlantic Wood Site, Portsmouth, VA USA. Aquat Toxicol. 2016;177:74-85 pubmed publisher
    Atlantic killifish, Fundulus heteroclitus, are adapted to creosote-based PAHs at the US EPA Superfund site known as Atlantic Wood (AW) on the southern branch of the Elizabeth River, VA USA...
  57. Podrabsky J, Wilson N. Hypoxia and Anoxia Tolerance in the Annual Killifish Austrofundulus limnaeus. Integr Comp Biol. 2016;56:500-9 pubmed publisher
    Embryos of the annual killifish Austrofundulus limnaeus are routinely exposed to oxygen limitation during development and are extremely tolerant of anoxia...
  58. Chung D, Sparagna G, Chicco A, Schulte P. Patterns of mitochondrial membrane remodeling parallel functional adaptations to thermal stress. J Exp Biol. 2018;221: pubmed publisher
    ..Using northern and southern subspecies of Atlantic killifish (Fundulus heteroclitus) that are locally adapted to different environmental temperatures, we assessed whether thermal ..
  59. Podrabsky J, Hand S. Physiological strategies during animal diapause: lessons from brine shrimp and annual killifish. J Exp Biol. 2015;218:1897-906 pubmed publisher
    ..The brine shrimp Artemia franciscana and annual killifish Austrofundulus limnaeus share strikingly similar life histories that include embryonic diapause as a means to ..
  60. McAroe C, Craig C, Holland R. Place versus response learning in fish: a comparison between species. Anim Cogn. 2016;19:153-61 pubmed publisher
    ..In this series of experiments, the spatial memory of four different species of fish (goldfish, killifish, zebrafish and Siamese fighting fish) was analysed using a plus maze set-up...
  61. Carr D, Smith E, Thiyagarajah A, Cromie M, Crumly C, Davis A, et al. Assessment of gonadal and thyroid histology in Gulf killifish (Fundulus grandis) from Barataria Bay Louisiana one year after the Deepwater Horizon oil spill. Ecotoxicol Environ Saf. 2018;154:245-254 pubmed publisher
    We examined gonads and thyroid glands of Gulf killifish (Fundulus grandis) 1yr after the Deepwater Horizon oil spill. F. grandis were trapped from two impacted sites in Barataria Bay (Bayou St...
  62. Szymkowicz D, Schwendinger K, Tatnall C, Swetenburg J, Bain L. Embryonic-only arsenic exposure alters skeletal muscle satellite cell function in killifish (Fundulus heteroclitus). Aquat Toxicol. 2018;198:276-286 pubmed publisher
    ..The purpose of this study was to use Fundulus heteroclitus or killifish as a model organism to determine if embryonic-only arsenic exposure permanently reduces the ..
  63. Glinka C, Frasca S, Provatas A, Lama T, Deguise S, Bosker T. The effects of model androgen 5α-dihydrotestosterone on mummichog (Fundulus heteroclitus) reproduction under different salinities. Aquat Toxicol. 2015;165:266-76 pubmed publisher
    ..short-term reproductive bioassay was conducted under conditions of low and high salinity using mummichog (Fundulus heteroclitus), a euryhaline species that is native to the east coast of North America...
  64. Ransberry V, Blewett T, McClelland G. The oxidative stress response in freshwater-acclimated killifish (Fundulus heteroclitus) to acute copper and hypoxia exposure. Comp Biochem Physiol C Toxicol Pharmacol. 2016;179:11-8 pubmed publisher
    ..Here we examine the effects of moderate hypoxia and low-level copper (Cu) on freshwater (FW)-acclimated killifish. Both Cu and hypoxia can affect oxidative stress in fish, but it is unclear if in combination these two ..
  65. Evans D, Hyndman K, Cornwell E, Buchanan P. Urotensin II and its receptor in the killifish gill: regulators of NaCl extrusion. J Exp Biol. 2011;214:3985-91 pubmed publisher
    ..inhibition of gill transport, we have cloned the cDNA encoding UII and UT from the euryhaline killifish (Fundulus heteroclitus L...
  66. Harel I, Valenzano D, Brunet A. Efficient genome engineering approaches for the short-lived African turquoise killifish. Nat Protoc. 2016;11:2010-2028 pubmed publisher
    ..Here we present a comprehensive protocol for efficient genome engineering in the African turquoise killifish (Nothobranchius furzeri), which is the shortest-lived vertebrate in captivity with a median life span of 4-6 ..
  67. Lloyd N, Janssen S, Reinfelder J, Barkay T. Co-selection of Mercury and Multiple Antibiotic Resistances in Bacteria Exposed to Mercury in the Fundulus heteroclitus Gut Microbiome. Curr Microbiol. 2016;73:834-842 pubmed
    ..of Hg and antibiotic-resistant bacteria that colonize the gastrointestinal tract of the mummichog (Fundulus heteroclitus), a small, estuarine fish...
  68. Ripa R, Dolfi L, Terrigno M, Pandolfini L, Savino A, Arcucci V, et al. MicroRNA miR-29 controls a compensatory response to limit neuronal iron accumulation during adult life and aging. BMC Biol. 2017;15:9 pubmed publisher
    ..Here, we show that microRNA-29 (miR-29) is induced during aging in short-lived turquoise killifish brain and genetic antagonism of its function induces a gene-expression signature typical of aging...
  69. Borowiec B, Darcy K, Gillette D, Scott G. Distinct physiological strategies are used to cope with constant hypoxia and intermittent hypoxia in killifish (Fundulus heteroclitus). J Exp Biol. 2015;218:1198-211 pubmed publisher
    ..distinct effects on hypoxia tolerance or on several determinants of O2 transport and O2 utilization in estuarine killifish. Adult killifish were acclimated to normoxia, constant hypoxia, or intermittent hypoxia for 7 or 28 days ..
  70. Silva R. Rivulus berovidesi, a new killifish species (Teleostei: Rivulidae) from western Cuba. Zootaxa. 2015;3949:289-96 pubmed publisher
    Rivulus berovidesi, a new killifish species, is described from a small stream in Sierra de Cajalbana, northwestern Cuba...
  71. Matson C, Bone A, Auffan M, Lindberg T, Arnold M, Hsu Kim H, et al. Silver toxicity across salinity gradients: the role of dissolved silver chloride species (AgCl x ) in Atlantic killifish (Fundulus heteroclitus) and medaka (Oryzias latipes) early life-stage toxicity. Ecotoxicology. 2016;25:1105-18 pubmed publisher
    The influence of salinity on Ag toxicity was investigated in Atlantic killifish (Fundulus heteroclitus) early life-stages. Embryo mortality was significantly reduced as salinity increased and Ag(+) was converted to AgCl(solid)...
  72. Philippe C, Grégoir A, Janssens L, Pinceel T, De Boeck G, Brendonck L. Acute and chronic sensitivity to copper of a promising ecotoxicological model species, the annual killifish Nothobranchius furzeri. Ecotoxicol Environ Saf. 2017;144:26-35 pubmed publisher
    ..The successful application of current ecotoxicological protocols on N. furzeri and its sensitivity range comparable to that of other model organisms forms the basis to exploit this species in further ecotoxicological practices. ..
  73. García G, Ríos N, Gutiérrez V. Next-generation sequencing detects repetitive elements expansion in giant genomes of annual killifish genus Austrolebias (Cyprinodontiformes, Rivulidae). Genetica. 2015;143:353-60 pubmed publisher
    Among Neotropical fish fauna, the South American killifish genus Austrolebias (Cyprinodontiformes: Rivulidae) constitutes an excellent model to study the genomic evolutionary processes underlying speciation events...
  74. Du X, Crawford D, Nacci D, Oleksiak M. Heritable oxidative phosphorylation differences in a pollutant resistant Fundulus heteroclitus population. Aquat Toxicol. 2016;177:44-50 pubmed publisher
    ..differences in hepatocyte oxidative phosphorylation (OxPhos) metabolism in field-caught killifish (Fundulus heteroclitus) from the highly polluted Elizabeth River, VA, USA, relative to fish from a nearby, relatively unpolluted ..
  75. Kim B, Lee M, Kang H, Rhee J, Lee J. Genomic organization and transcriptional modulation in response to endocrine disrupting chemicals of three vitellogenin genes in the self-fertilizing fish Kryptolebias marmoratus. J Environ Sci (China). 2016;42:187-195 pubmed publisher
    ..To examine the biomarker potential of the self-fertilizing killifish Kryptolebias marmoratus Vtgs (Km-Vtgs), full genomic DNAs of Km-Vtgs-Aa, Km-Vtgs-Ab, and Km-Vtgs-C were cloned, ..
  76. Xie L, Wu X, Chen H, Dong W, Cazan A, Klerks P. A low level of dietary selenium has both beneficial and toxic effects and is protective against Cd-toxicity in the least killifish Heterandria formosa. Chemosphere. 2016;161:358-364 pubmed publisher
    ..The present study assessed the effects of dietary exposure to Se in the least killifish Heterandria formosa, and investigated how this exposure influences the effects of a subsequent exposure to ..
  77. Chung D, Schulte P. Mechanisms and costs of mitochondrial thermal acclimation in a eurythermal killifish (Fundulus heteroclitus). J Exp Biol. 2015;218:1621-31 pubmed publisher
    ..we examined how mitochondrial properties are affected by thermal acclimation in the eurythermal killifish, Fundulus heteroclitus - a species with substantial plasticity in whole-organism thermal limits...
  78. Brennan R, Hwang R, Tse M, Fangue N, Whitehead A. Local adaptation to osmotic environment in killifish, Fundulus heteroclitus, is supported by divergence in swimming performance but not by differences in excess post-exercise oxygen consumption or aerobic scope. Comp Biochem Physiol A Mol Integr Physiol. 2016;196:11-19 pubmed publisher
    ..Killifish, Fundulus heteroclitus, occupy estuarine habitats where salinities range from fresh to seawater...
  79. Ito K, Ito M, Onduka T, Ohta K, Torii T, Hano T, et al. Differences in the ability of two marine annelid species, Thalassodrilides sp. and Perinereis nuntia, to detoxify 1-nitronaphthalene. Chemosphere. 2016;151:339-44 pubmed publisher
    ..We then tested the acute toxicity of residual 1-nitronaphthalene from the same water using mummichog (fish) larvae...
  80. Singer T, Tucker S, Marshall W, Higgins C. A divergent CFTR homologue: highly regulated salt transport in the euryhaline teleost F. heteroclitus. Am J Physiol. 1998;274:C715-23 pubmed
    The killifish, Fundulus heteroclitus, is a euryhaline teleost fish capable of adapting rapidly to transfer from freshwater (FW) to four times seawater (SW). To investigate osmoregulation at a molecular level, a 5...
  81. Kozak G, Roland G, Rankhorn C, Falater A, Berdan E, Fuller R. Behavioral Isolation due to Cascade Reinforcement in Lucania Killifish. Am Nat. 2015;185:491-506 pubmed publisher
    ..We measured behavioral isolation between sympatric and allopatric populations of Lucania killifish to determine whether isolation evolves due to reinforcement between species and whether reinforcement affects ..
  82. Gerber L, Jensen F, Madsen S, Marshall W. Nitric oxide inhibition of NaCl secretion in the opercular epithelium of seawater-acclimated killifish, Fundulus heteroclitus. J Exp Biol. 2016;219:3455-3464 pubmed
    ..We explored the involvement of NO in controlling NaCl secretion by the opercular epithelium of seawater killifish using an Ussing chamber approach...
  83. Wendler S, Hartmann N, Hoppe B, Englert C. Age-dependent decline in fin regenerative capacity in the short-lived fish Nothobranchius furzeri. Aging Cell. 2015;14:857-66 pubmed publisher
    ..Here, we used the short-lived killifish Nothobranchius furzeri to analyse the impact of aging on fin regeneration in more detail...
  84. Townley I, Karchner S, Skripnikova E, Wiese T, Hahn M, Rees B. Sequence and functional characterization of hypoxia-inducible factors, HIF1α, HIF2αa, and HIF3α, from the estuarine fish, Fundulus heteroclitus. Am J Physiol Regul Integr Comp Physiol. 2017;312:R412-R425 pubmed publisher
    ..The estuarine fish Fundulus heteroclitus is found in habitats prone to hypoxia...
  85. Doyle M, Bosker T, Martyniuk C, MacLatchy D, Munkittrick K. The effects of 17-?-ethinylestradiol (EE2) on molecular signaling cascades in mummichog (Fundulus heteroclitus). Aquat Toxicol. 2013;134-135:34-46 pubmed publisher
    ..EE2) will reduce or shut down egg production in freshwater fish models, while mummichog (Fundulus heteroclitus), an estuarine species, are able to produce eggs at EE2 concentrations >3000 ng/L...
  86. Tait J, Mercer E, Gerber L, Robertson G, Marshall W. Osmotic versus adrenergic control of ion transport by ionocytes of Fundulus heteroclitus in the cold. Comp Biochem Physiol A Mol Integr Physiol. 2017;203:255-261 pubmed publisher
    ..These data are consistent with a shift in these eurythermic animals from complex adrenergic control to relatively simple biomechanical osmotic control of ion secretion in the cold. ..
  87. McKenzie J, Bucking C, Moreira A, Schulte P. Intrinsic reproductive isolating mechanisms in the maintenance of a hybrid zone between ecologically divergent subspecies. J Evol Biol. 2017;30:848-864 pubmed publisher
    ..zone of this intermediate type occurring between northern and southern subspecies of Atlantic killifish, Fundulus heteroclitus, to identify isolating mechanisms playing a role in maintaining this type of zone...
  88. Lee B, Kim D, Kim H, Kim B, Han J, Lee J. Identification of 74 cytochrome P450 genes and co-localized cytochrome P450 genes of the CYP2K, CYP5A, and CYP46A subfamilies in the mangrove killifish Kryptolebias marmoratus. BMC Genomics. 2018;19:7 pubmed publisher
    The mangrove killifish Kryptolebias marmoratus is the only vertebrate that reproduces by self-fertilizing and is an important model species in genetics and marine ecotoxicology...
  89. Rigaud C, Couillard C, Pellerin J, Légaré B, Gonzalez P, Hodson P. Relative potency of PCB126 to TCDD for sublethal embryotoxicity in the mummichog (Fundulus heteroclitus). Aquat Toxicol. 2013;128-129:203-14 pubmed publisher
    ..PCB126) to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) for sublethal responses was assessed in Fundulus heteroclitus embryos...
  90. Jung D, Adamo M, Lehman R, Barnaby R, Jackson C, Jackson B, et al. A novel variant of aquaporin 3 is expressed in killifish (Fundulus heteroclitus) intestine. Comp Biochem Physiol C Toxicol Pharmacol. 2015;171:1-7 pubmed publisher
    Killifish (Fundulus heteroclitus) are euryhaline teleosts that are widely used in environmental and toxicological studies, and they are tolerant to arsenic, in part due to very low assimilation of arsenic from the environment...
  91. Reichwald K, Petzold A, Koch P, Downie B, Hartmann N, Pietsch S, et al. Insights into Sex Chromosome Evolution and Aging from the Genome of a Short-Lived Fish. Cell. 2015;163:1527-38 pubmed publisher
    The killifish Nothobranchius furzeri is the shortest-lived vertebrate that can be bred in the laboratory...
  92. Lindberg C, Jayasundara N, Kozal J, Leuthner T, Di Giulio R. Resistance to polycyclic aromatic hydrocarbon toxicity and associated bioenergetic consequences in a population of Fundulus heteroclitus. Ecotoxicology. 2017;26:435-448 pubmed publisher
    ..Interestingly, some populations of Atlantic killifish (Fundulus heteroclitus) inhabiting the Elizabeth River (ER) are resistant to PAH-induced teratogenesis...