Dumeril's clam worm


Alias: Platynereis dumerilii, Platynereis dumerilii (Audouin & Milne-Edwards, 1833), Platynereis dumerlii

Top Publications

  1. Williams E, Jekely G. Neuronal cell types in the annelid Platynereis dumerilii. Curr Opin Neurobiol. 2019;56:106-116 pubmed publisher
    The marine annelid Platynereis dumerilii is an invertebrate laboratory model for developmental biology and neuroscience...
  2. Bannister S, Antonova O, Polo A, Lohs C, Hallay N, Valinciute A, et al. TALENs mediate efficient and heritable mutation of endogenous genes in the marine annelid Platynereis dumerilii. Genetics. 2014;197:77-89 pubmed publisher
    b>Platynereis dumerilii is a marine polychaete and an established model system for studies of evolution and development...
  3. Marlow H, Tosches M, Tomer R, Steinmetz P, Lauri A, Larsson T, et al. Larval body patterning and apical organs are conserved in animal evolution. BMC Biol. 2014;12:7 pubmed publisher
    ..regionalization of the episphere, the upper hemisphere of the trochophore larva of the marine annelid Platynereis dumerilii. We examined the spatial distribution of transcription factors and of Wnt signaling components previously ..
  4. Steinmetz P, Urbach R, Posnien N, Eriksson J, Kostyuchenko R, Brena C, et al. Six3 demarcates the anterior-most developing brain region in bilaterian animals. Evodevo. 2010;1:14 pubmed publisher
    ..We find that in the marine annelid Platynereis dumerilii, expression of the homeobox gene six3 defines the apical region of the larval body, peripherally ..
  5. Conzelmann M, Williams E, Krug K, Franz Wachtel M, Macek B, Jekely G. The neuropeptide complement of the marine annelid Platynereis dumerilii. BMC Genomics. 2013;14:906 pubmed publisher
    The marine annelid Platynereis dumerilii is emerging as a powerful lophotrochozoan experimental model for evolutionary developmental biology (evo-devo) and neurobiology...
  6. Randel N, Bezares Calderón L, Gühmann M, Shahidi R, Jekely G. Expression dynamics and protein localization of rhabdomeric opsins in Platynereis larvae. Integr Comp Biol. 2013;53:7-16 pubmed publisher
    ..The early trochophore larvae of the errant annelid Platynereis dumerilii have a single pair of ventral eyespots, whereas older nectochaete larvae have an additional two pairs of ..
  7. Fischer A, Henrich T, Arendt D. The normal development of Platynereis dumerilii (Nereididae, Annelida). Front Zool. 2010;7:31 pubmed publisher
    The polychaete annelid Platynereis dumerilii is an emerging model organism for the study of molecular developmental processes, evolution, neurobiology and marine biology...
  8. Backfisch B, Veedin Rajan V, Fischer R, Lohs C, Arboleda E, Tessmar Raible K, et al. Stable transgenesis in the marine annelid Platynereis dumerilii sheds new light on photoreceptor evolution. Proc Natl Acad Sci U S A. 2013;110:193-8 pubmed publisher
    ..Our study marks significant advance for the understanding of photoreceptor cell (PRC) evolution and development and for Platynereis as a functional lophotrochozoan model system. ..
  9. Chartier T, Deschamps J, Dürichen W, Jekely G, Arendt D. Whole-head recording of chemosensory activity in the marine annelid Platynereis dumerilii. Open Biol. 2018;8: pubmed publisher
    ..Here, we study the marine worm Platynereis dumerilii to provide the first comprehensive investigation of head chemosensory organ physiology in an annelid...

More Information


  1. Planques A, Malem J, Parapar J, Vervoort M, Gazave E. Morphological, cellular and molecular characterization of posterior regeneration in the marine annelid Platynereis dumerilii. Dev Biol. 2019;445:189-210 pubmed publisher
    ..Here, we present a study of regeneration of the marine annelid Platynereis dumerilii, an emerging comparative developmental biology model, which, like many other annelids, displays important ..
  2. Chou H, Acevedo Luna N, Kuhlman J, Schneider S. PdumBase: a transcriptome database and research tool for Platynereis dumerilii and early development of other metazoans. BMC Genomics. 2018;19:618 pubmed publisher
    The marine polychaete annelid Platynereis dumerilii has recently emerged as a prominent organism for the study of development, evolution, stem cells, regeneration, marine ecology, chronobiology and neurobiology within metazoans...
  3. Lauri A, Brunet T, Handberg Thorsager M, Fischer A, Simakov O, Steinmetz P, et al. Development of the annelid axochord: insights into notochord evolution. Science. 2014;345:1365-8 pubmed publisher
    ..We identify a population of mesodermal cells in a developing invertebrate, the marine annelid Platynereis dumerilii, that converges and extends toward the midline and expresses a notochord-specific combination of genes...
  4. Tosches M, Bucher D, Vopalensky P, Arendt D. Melatonin signaling controls circadian swimming behavior in marine zooplankton. Cell. 2014;159:46-57 pubmed publisher
    ..effect of melatonin signaling on circadian swimming behavior in a zooplankton model, the marine annelid Platynereis dumerilii. We find that melatonin is produced in brain photoreceptors with a vertebrate-type opsin-based ..
  5. Verasztó C, Ueda N, Bezares Calderón L, Panzera A, Williams E, Shahidi R, et al. Ciliomotor circuitry underlying whole-body coordination of ciliary activity in the Platynereis larva. elife. 2017;6: pubmed publisher
    ..To understand how such coordination is achieved, we studied the ciliated larvae of Platynereis dumerilii, a marine annelid...
  6. Asadulina A, Conzelmann M, Williams E, Panzera A, Jékely G. Object-based representation and analysis of light and electron microscopic volume data using Blender. BMC Bioinformatics. 2015;16:229 pubmed publisher
    ..expression atlases and electron microscopy connectome volume data from larval stages of the marine annelid Platynereis dumerilii. We build object-based larval gene expression atlases in Blender and develop tools for annotation and ..
  7. Gühmann M, Jia H, Randel N, Verasztó C, Bezares Calderón L, Michiels N, et al. Spectral Tuning of Phototaxis by a Go-Opsin in the Rhabdomeric Eyes of Platynereis. Curr Biol. 2015;25:2265-71 pubmed publisher
    ..Here, we characterize a Go-opsin from the marine annelid Platynereis dumerilii. We found Go-opsin1 coexpressed with two r-opsins in depolarizing rhabdomeric photoreceptor cells in the ..
  8. Wäge J, Hardege J, Larsson T, Simakov O, Chapman E, Arendt D, et al. Effects of low seawater pH on the marine polychaete Platynereis dumerilii. Mar Pollut Bull. 2015;95:166-72 pubmed publisher
    ..partial Na(+)/H(+)exchangers (NHE), carbonic anhydrase (CA), and calmodulin (CaM) genes from a polychaete, Platynereis dumerilii and investigate their relative expression in acidified seawater conditions...
  9. Ayers T, Tsukamoto H, Gühmann M, Veedin Rajan V, Tessmar Raible K. A Go-type opsin mediates the shadow reflex in the annelid Platynereis dumerilii. BMC Biol. 2018;16:41 pubmed publisher
    ..photoreceptor molecule of the Go-opsin class in the shadow response of the marine bristle worm Platynereis dumerilii. We found Pdu-Go-opsin1 expression in single specialised cells located in adult Platynereis head and trunk ..
  10. Ricevuto E, Benedetti M, Regoli F, Spicer J, Gambi M. Antioxidant capacity of polychaetes occurring at a natural CO2 vent system: Results of an in situ reciprocal transplant experiment. Mar Environ Res. 2015;112:44-51 pubmed publisher
    ..Here, selected polychaete species, Platynereis dumerilii, Polyophthalmus pictus and Syllis prolifera, were sampled from a natural CO2 vent system (pH = 7...
  11. Pfeifer K, Schaub C, Domsch K, Dorresteijn A, Wolfstetter G. Maternal inheritance of twist and analysis of MAPK activation in embryos of the polychaete annelid Platynereis dumerilii. PLoS ONE. 2014;9:e96702 pubmed publisher
    ..aimed to identify molecular mechanisms involved in the specification of the 4d (mesentoblast) lineage in Platynereis dumerilii. We employ RT-PCR and in situ hybridization against the Platynereis dumerilii twist homolog (Pdu-twist) to ..
  12. Demilly A, Simionato E, Ohayon D, Kerner P, Garcès A, Vervoort M. Coe genes are expressed in differentiating neurons in the central nervous system of protostomes. PLoS ONE. 2011;6:e21213 pubmed publisher
    ..the CNS expression of coe genes in the insect Drosophila melanogaster and the polychaete annelid Platynereis dumerilii, which belong to different subgroups of protostomes and show strikingly different modes of development...
  13. Wäge J, Lerebours A, Hardege J, Rotchell J. Exposure to low pH induces molecular level changes in the marine worm, Platynereis dumerilii. Ecotoxicol Environ Saf. 2016;124:105-110 pubmed publisher
    ..subtractive hybridisation (SSH) approach to characterise differentially expressed genes isolated from Platynereis dumerilii, a non-calcifying marine polychaeta species, kept at normal and low pH conditions...
  14. Gong T, Zhang X, Li Y, Xian Q. Formation and toxicity of halogenated disinfection byproducts resulting from linear alkylbenzene sulfonates. Chemosphere. 2016;149:70-5 pubmed publisher
    ..overall toxicity of different scenarios of LAS samples was evaluated with embryos of a marine polychaete Platynereis dumerilii. The results demonstrate that chlorinated DBPs were generated during chlorination of LAS without bromide, ..
  15. Randel N, Jekely G. Phototaxis and the origin of visual eyes. Philos Trans R Soc Lond B Biol Sci. 2016;371:20150042 pubmed publisher
    ..of the complete neural circuitry (connectome) of an elementary visual system in the larva of the annelid Platynereis dumerilii sheds new light on the possible paths from non-visual to visual phototaxis and to image-forming vision...
  16. Starunov V, Dray N, Belikova E, Kerner P, Vervoort M, Balavoine G. A metameric origin for the annelid pygidium?. BMC Evol Biol. 2015;15:25 pubmed publisher
    ..and a number of molecular markers, we describe the neural and mesodermal structures of the pygidium of Platynereis dumerilii. We establish that the pygidium possesses a complicated nervous system with a nerve ring and a pair of ..
  17. Tsukamoto H, Chen I, Kubo Y, Furutani Y. A ciliary opsin in the brain of a marine annelid zooplankton is ultraviolet-sensitive, and the sensitivity is tuned by a single amino acid residue. J Biol Chem. 2017;292:12971-12980 pubmed publisher
    ..Larvae of the annelid Platynereis dumerilii are used as a zooplankton model, and this zooplankton species possesses a "vertebrate-type" ciliary ..
  18. André A, Ruivo R, Capitão A, Froufe E, Páscoa I, Costa Castro L, et al. Cloning and functional characterization of a retinoid X receptor orthologue in Platynereis dumerilii: An evolutionary and toxicological perspective. Chemosphere. 2017;182:753-761 pubmed publisher
    ..provide the first isolation and functional characterization of a RXR orthologue in an annelid species, the Platynereis dumerilii. Using an in vitro luciferase reporter assay we evaluated the annelid receptor ability to respond to ..
  19. Yuan H, Wang W, Hu B, Pan C, Chen M, Ke L, et al. Cloning and Functional Analysis of Pax6 from the Hydrothermal Vent Tubeworm Ridgeia piscesae. PLoS ONE. 2016;11:e0168579 pubmed publisher
    ..analysis indicates that it clusters with the corresponding sequence from the closely related species Platynereis dumerilii (P. dumerilii) of Annelida...
  20. Williams E, Jekely G. Towards a systems-level understanding of development in the marine annelid Platynereis dumerilii. Curr Opin Genet Dev. 2016;39:175-181 pubmed publisher
    b>Platynereis dumerilii is a segmented marine worm from the phylum Annelida, a member of the Lophotrochozoans...
  21. Bauknecht P, Jekely G. Ancient coexistence of norepinephrine, tyramine, and octopamine signaling in bilaterians. BMC Biol. 2017;15:6 pubmed publisher
    ..In the protostomes Platynereis dumerilii (an annelid) and Priapulus caudatus (a priapulid), we have identified and pharmacologically characterized ..
  22. Chou H, Pruitt M, Bastin B, Schneider S. A transcriptional blueprint for a spiral-cleaving embryo. BMC Genomics. 2016;17:552 pubmed publisher
    ..To address this gap we use RNA-sequencing on the spiralian model Platynereis dumerilii to capture and quantify the first complete genome-wide transcriptional landscape of early spiral cleavage...
  23. Lv L, Dong X, Lv F, Zhao W, Yu Y, Yang W. Molecular cloning and characterization of an estrogen receptor gene in the marine polychaete Perinereis aibuhitensis. Comp Biochem Physiol B Biochem Mol Biol. 2017;207:15-21 pubmed publisher
    ..A phylogenetic analysis revealed that paER is an orthologue of ER in the polychaete Platynereis dumerilii. A tissue distribution analysis of paER mRNA showed that it is expressed in various tissues, including the ..
  24. Vergara H, Bertucci P, Hantz P, Tosches M, Achim K, Vopalensky P, et al. Whole-organism cellular gene-expression atlas reveals conserved cell types in the ventral nerve cord of Platynereis dumerilii. Proc Natl Acad Sci U S A. 2017;114:5878-5885 pubmed publisher
    ..We investigate three-segmented young worms of the marine annelid Platynereis dumerilii, with a rich diversity of differentiated cells present in relatively low number...
  25. Uchiyama H, Maehara S, Ohta H, Seki T, Tanaka Y. Elevenin regulates the body color through a G protein-coupled receptor NlA42 in the brown planthopper Nilaparvata lugens. Gen Comp Endocrinol. 2018;258:33-38 pubmed publisher
    ..and a G protein-coupled receptor (GPCR) NlA42 that is homologous to the elevenin receptor of the annelid Platynereis dumerilii. RNA interference (RNAi)-mediated knockdown of either Nl-elevenin or the NlA42 gene resulted in cuticle ..
  26. Ponesakki V, Paul S, Mani D, Rajendiran V, Kanniah P, Sivasubramaniam S. Annotation of nerve cord transcriptome in earthworm Eisenia fetida. Genom Data. 2017;14:91-105 pubmed publisher
    ..contig dataset exhibited 22 crucial neuropeptides having considerable matches to the marine annelid Platynereis dumerilii, suggesting their possible role in neurotransmission and neuromodulation...
  27. Boore J, Brown W. Mitochondrial genomes of Galathealinum, Helobdella, and Platynereis: sequence and gene arrangement comparisons indicate that Pogonophora is not a phylum and Annelida and Arthropoda are not sister taxa. Mol Biol Evol. 2000;17:87-106 pubmed publisher
    ..Nucleotide composition bias appears to influence amino acid composition of the proteins...
  28. Gazave E, Lemaître Q, Balavoine G. The Notch pathway in the annelid Platynereis: insights into chaetogenesis and neurogenesis processes. Open Biol. 2017;7: pubmed publisher
    ..Here, we explore the functions of Notch in the annelid Platynereis dumerilii (Lophotrochozoa)...
  29. Williams E, Verasztó C, Jasek S, Conzelmann M, Shahidi R, Bauknecht P, et al. Synaptic and peptidergic connectome of a neurosecretory centre in the annelid brain. elife. 2017;6: pubmed publisher
    ..reconstructed 78 neurosecretory neurons and mapped their synaptic connectivity in the brain of larval Platynereis dumerilii, a marine annelid...
  30. Nakama A, Chou H, Schneider S. The asymmetric cell division machinery in the spiral-cleaving egg and embryo of the marine annelid Platynereis dumerilii. BMC Dev Biol. 2017;17:16 pubmed publisher
    ..To do so we analyzed stage-specific transcriptome data in eggs and early embryos of the spiralian annelid Platynereis dumerilii for the expression of over 50 candidate genes that are involved in (1) establishing cortical domains such ..
  31. Ozpolat B, Handberg Thorsager M, Vervoort M, Balavoine G. Cell lineage and cell cycling analyses of the 4d micromere using live imaging in the marine annelid Platynereis dumerilii. elife. 2017;6: pubmed publisher
    ..In this study on the marine annelid Platynereis dumerilii, we investigated the lineage of the 4d micromere, using high-resolution long-term live imaging ..
  32. Li Y, Zhang X, Yang M, Liu J, Li W, Graham N, et al. Three-step effluent chlorination increases disinfection efficiency and reduces DBP formation and toxicity. Chemosphere. 2017;168:1302-1308 pubmed publisher
    ..three-step chlorination was evaluated in terms of the development of embryo-larva of a marine polychaete Platynereis dumerilii. The results revealed that the primary sewage effluent with three-step chlorination was less toxic than ..