Yersinia pestis

Summary

Alias: "Bacillus pestis" (Lehmann and Neumann 1896) Migula 1900, "Bacterium pestis" Lehmann and Neumann 1896, "Pasteurella pestis" (Lehmann and Neumann 1896) Bergey et al. 1923, "Pestisella pestis" (Lehmann and Neumann 1896) Dorofeev 1947, Bacillus pestis, Bacterium pestis, Pasteurella pestis, Pestisella pestis, Yersinia pestis (Lehmann and Neumann 1896) van Loghem 1944 (Approved Lists 1980), nom. cons, Yersinia pseudotuberculosis subsp. pestis, Yersinia pseudotuberculosis subsp. pestis (Lehmann and Neumann 1896) Bercovier et al. 1981

Top Publications

  1. Lilo S, Zheng Y, Bliska J. Caspase-1 activation in macrophages infected with Yersinia pestis KIM requires the type III secretion system effector YopJ. Infect Immun. 2008;76:3911-23 pubmed publisher
    ..Naïve murine macrophages were infected with a panel of different Yersinia pestis and Yersinia pseudotuberculosis strains to determine whether Yops of these species inhibit caspase-1 ..
  2. Dewoody R, Merritt P, Marketon M. YopK controls both rate and fidelity of Yop translocation. Mol Microbiol. 2013;87:301-17 pubmed publisher
    b>Yersinia pestis, the causative agent of plague, utilizes a type III secretion system (T3SS) to intoxicate host cells...
  3. Watson A, Ellington S, Nelson C, Treadwell T, Jamieson D, Meaney Delman D. Preparing for biological threats: Addressing the needs of pregnant women. Birth Defects Res. 2017;109:391-398 pubmed publisher
    ..botulinum toxin (botulism); Burkholderia mallei (glanders) and Burkholderia pseudomallei (melioidosis); Yersinia pestis (plague); Francisella tularensis (tularemia); and Rickettsia prowazekii (typhus)...
  4. Liu J, Ochieng C, Wiersma S, Ströher U, Towner J, Whitmer S, et al. Development of a TaqMan Array Card for Acute-Febrile-Illness Outbreak Investigation and Surveillance of Emerging Pathogens, Including Ebola Virus. J Clin Microbiol. 2016;54:49-58 pubmed publisher
    ..Rickettsia spp., Salmonella enterica and Salmonella enterica serovar Typhi, and Yersinia pestis), and 3 protozoa (Leishmania spp., Plasmodium spp., and Trypanosoma brucei)...
  5. Kostyrko V, Bertsova Y, Serebryakova M, Baykov A, Bogachev A. NqrM (DUF539) Protein Is Required for Maturation of Bacterial Na+-Translocating NADH:Quinone Oxidoreductase. J Bacteriol. 2015;198:655-63 pubmed publisher
    ..Neisseria gonorrhoeae, Pasteurella multocida, Porphyromonas gingivalis, Enterobacter aerogenes, and Yersinia pestis. Production of Na(+)-NQR in bacteria requires Na(+)-NQR-specific maturation factors...
  6. Sabbatani S. [The experiments conducted by Japanese on human guinea pigs, and the use of biological weapons during the Sino-Japanese war (1937-1945)]. Infez Med. 2014;22:255-66 pubmed
    ..with firearms, and bone fractures, were performed, as well as the inoculation of microorganisms (including Yersinia pestis, Vibrio cholerae, Richettsia typhi, and Salmonella typhi), and spores of Bacillus anthracis...
  7. Rosenzweig J, Ahmed S, Eunson J, Chopra A. Low-shear force associated with modeled microgravity and spaceflight does not similarly impact the virulence of notable bacterial pathogens. Appl Microbiol Biotechnol. 2014;98:8797-807 pubmed publisher
    ..g., hypovirulence of Yersinia pestis in cell culture infections and hypovirulence of methicillin-resistant Staphylococcus aureus, Enterococcus ..
  8. Galy A, Loubet P, Peiffer Smadja N, Yazdanpanah Y. [The plague: An overview and hot topics]. Rev Med Interne. 2018;: pubmed publisher
    Plague is a bacterial zoonosis caused by Yersinia pestis, usually found in fleas and small rodents that constitute the reservoir of the disease...
  9. Silbereisen A, Tamborrini M, Wittwer M, Schürch N, Pluschke G. Development of a bead-based Luminex assay using lipopolysaccharide specific monoclonal antibodies to detect biological threats from Brucella species. BMC Microbiol. 2015;15:198 pubmed publisher
    ..Bacillus anthracis, Francisella tularensis and Yersinia pestis within a single sample. Overall, the robust Luminex assay should allow detection of Brucella spp...

More Information

Publications193 found, 100 shown here

  1. Suntsov V. [On the origin of Yersinia pestis, a causative agent of the plague: A concept of population-genetic macroevolution in transitive environment]. Zh Obshch Biol. 2015;76:310-8 pubmed
    ..All the present intraspecies forms of Y. pestis that appeared due to microevolution, have originated with the subspecies Y. pestis tarbagani that has formed in Central Asia during the Sartan cooling. ..
  2. Bartra S, Ding Y, Fujimoto L, Ring J, Jain V, Ram S, et al. Yersinia pestis uses the Ail outer membrane protein to recruit vitronectin. Microbiology. 2015;161:2174-83 pubmed publisher
    b>Yersinia pestis, the agent of plague, requires the Ail (attachment invasion locus) outer membrane protein to survive in the blood and tissues of its mammalian hosts...
  3. Andrianaivoarimanana V, Bertherat E, Rajaonarison R, Rakotondramaro T, Rogier C, Rajerison M. Mixed pneumonic plague and nosocomial MDR-bacterial infection of lung: a rare case report. BMC Pulm Med. 2018;18:92 pubmed publisher
    Plague is a life-threatening disease caused by the bacterium, Yersinia pestis. Madagascar is the leading country for human plague cases worldwide. Human plague is a serious disease, particularly in its septicaemic and pneumonic forms...
  4. Korneev K, Kondakova A, Arbatsky N, Novototskaya Vlasova K, Rivkina E, Anisimov A, et al. Distinct biological activity of lipopolysaccharides with different lipid A acylation status from mutant strains of Yersinia pestis and some members of genus Psychrobacter. Biochemistry (Mosc). 2014;79:1333-8 pubmed publisher
    ..Wild-type LPS from plague-causing bacteria Yersinia pestis was compared to LPS from mutant strains with defects in acyltransferase genes (lpxM, lpxP) responsible for ..
  5. Arnaboldi P, Sambir M, D Arco C, Peters L, Seegers J, Mayer L, et al. Intranasal delivery of a protein subunit vaccine using a Tobacco Mosaic Virus platform protects against pneumonic plague. Vaccine. 2016;34:5768-5776 pubmed publisher
    b>Yersinia pestis, one of history's deadliest pathogens, has killed millions over the course of human history...
  6. Lewnard J, Townsend J. Climatic and evolutionary drivers of phase shifts in the plague epidemics of colonial India. Proc Natl Acad Sci U S A. 2016;113:14601-14608 pubmed publisher
    ..Plague presents an optimal system for interrogating such couplings: Yersinia pestis transmission exerts intense selective pressure driving the local persistence of disease resistance among its ..
  7. Nyirenda S, Hang Ombe B, Kilonzo B, Kangwa H, Mulenga E, Moonga L. Potential Roles of Pigs, Small Ruminants, Rodents, and Their Flea Vectors in Plague Epidemiology in Sinda District, Eastern Zambia. J Med Entomol. 2017;54:719-725 pubmed publisher
    ..on serum, and organs and fleas to determine IgG antibodies against Fraction 1 antigen and pla gene of Yersinia pestis, respectively. ELISA results showed that 2.83% (95% CI?=?0.59-8.05) rodents, 9.0% (95% CI?=?5.71-13...
  8. Rosales Mendoza S, Tello Olea M. Carrot cells: a pioneering platform for biopharmaceuticals production. Mol Biotechnol. 2015;57:219-32 pubmed publisher
    ..art comprises ten vaccine prototypes against Measles virus, Hepatitis B virus, Human immunodeficiency virus, Yersinia pestis, Chlamydia trachomatis, Mycobacterium tuberculosis, enterotoxigenic Escherichia coli, Corynebacterium ..
  9. Vagima Y, Zauberman A, Levy Y, Gur D, Tidhar A, Aftalion M, et al. Circumventing Y. pestis Virulence by Early Recruitment of Neutrophils to the Lungs during Pneumonic Plague. PLoS Pathog. 2015;11:e1004893 pubmed publisher
    Pneumonic plague is a fatal disease caused by Yersinia pestis that is associated with a delayed immune response in the lungs...
  10. Cai Y, Cao X, Aballay A. Whole-animal chemical screen identifies colistin as a new immunomodulator that targets conserved pathways. MBio. 2014;5: pubmed publisher
    ..these drugs, the last-resort antibiotic colistin, protected against infections by the Gram-negative pathogens Yersinia pestis and Pseudomonas aeruginosa but not by the Gram-positive pathogens Enterococcus faecalis and Staphylococcus ..
  11. Du Z, Wang X. Pathology and Pathogenesis of Yersinia pestis. Adv Exp Med Biol. 2016;918:193-222 pubmed
    ..pestis. ..
  12. Gregg K, Harberts E, Gardner F, Pelletier M, Cayatte C, Yu L, et al. Rationally Designed TLR4 Ligands for Vaccine Adjuvant Discovery. MBio. 2017;8: pubmed publisher
    ..In this study, BECC is applied within an avirulent strain of Yersinia pestis to develop structurally distinct LOS molecules that elicit differential Toll-like receptor 4 (TLR4) ..
  13. Cipolla D, Blanchard J, Gonda I. Development of Liposomal Ciprofloxacin to Treat Lung Infections. Pharmaceutics. 2016;8: pubmed publisher
    ..mycobacteria, fungal infections or potential inhaled biowarfare agents including Francisella tularensis, Yersinia pestis and Coxiella burnetii (which cause pneumonic tularemia, plague and Q fever, respectively)...
  14. Burnum Johnson K, Kyle J, Eisfeld A, Casey C, Stratton K, Gonzalez J, et al. MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling. Analyst. 2017;142:442-448 pubmed publisher
    ..inactivation of clinically important bacterial and viral pathogens with exposed lipid membranes, including Yersinia pestis, Salmonella Typhimurium, and Campylobacter jejuni in pure culture, and Yersinia pestis, Campylobacter jejuni, ..
  15. Giuffrida M, Mazzoli R, Pessione E. Back to the past: deciphering cultural heritage secrets by protein identification. Appl Microbiol Biotechnol. 2018;102:5445-5455 pubmed publisher
    ..markers that, for instance, were used to establish the cause of death of old Inca mummies and also proved the presence of Yersinia pestis in old documents dating from the period in 17th century in which the plague ravaged Europe.
  16. Nyirenda S, Hang Ombe B, Simulundu E, Mulenga E, Moonga L, Machang U R, et al. Molecular epidemiological investigations of plague in Eastern Province of Zambia. BMC Microbiol. 2018;18:2 pubmed publisher
    Plague is a flea-borne zoonotic and invasive disease caused by a gram negative coccobacillus bacterium called Yersinia pestis. Plague has caused three devastating pandemics globally namely: the Justinian, Black Death and Oriental plague...
  17. Mühlenkamp M, Oberhettinger P, Leo J, Linke D, Schütz M. Yersinia adhesin A (YadA)--beauty & beast. Int J Med Microbiol. 2015;305:252-8 pubmed publisher
    ..is expressed by enteropathogenic Yersinia enterocolitica and Yersinia pseudotuberculosis strains, but not by Yersinia pestis. A characteristic trait of YadA is its modular composition and trimeric nature...
  18. Jia Q, Bowen R, Dillon B, Maslesa Galic S, Chang B, Kaidi A, et al. Single vector platform vaccine protects against lethal respiratory challenge with Tier 1 select agents of anthrax, plague, and tularemia. Sci Rep. 2018;8:7009 pubmed publisher
    Bacillus anthracis, Yersinia pestis, and Francisella tularensis are the causative agents of Tier 1 Select Agents anthrax, plague, and tularemia, respectively...
  19. Maestas L, Britten H. Flea and Small Mammal Species Composition in Mixed-Grass Prairies: Implications for the Maintenance of Yersinia pestis. Vector Borne Zoonotic Dis. 2017;17:467-474 pubmed publisher
    ..Moreover this study demonstrates that although small mammals may not play a large part in interepizootic plague cycling in shortgrass prairie ecosystems, their role in mixed-grass prairies requires further evaluation. ..
  20. Drali R, Shako J, Davoust B, Diatta G, Raoult D. A New Clade of African Body and Head Lice Infected by Bartonella quintana and Yersinia pestis-Democratic Republic of the Congo. Am J Trop Med Hyg. 2015;93:990-3 pubmed publisher
    ..It is also suspected in the transmission of a fourth pathogen, Yersinia pestis, which is the etiologic agent of plague...
  21. Zvi A, Rotem S, Zauberman A, Elia U, Aftalion M, Bar Haim E, et al. Novel CTL epitopes identified through a Y. pestis proteome-wide analysis in the search for vaccine candidates against plague. Vaccine. 2017;35:5995-6006 pubmed publisher
    The causative agent of Plague, Yersinia pestis, is a highly virulent pathogen and a potential bioweapon. Depending on the route of infection, two prevalent occurrences of the disease are known, bubonic and pneumonic...
  22. Nyirenda S, Hang Ombe B, Machang u R, Mwanza J, Kilonzo B. Identification of Risk Factors Associated with Transmission of Plague Disease in Eastern Zambia. Am J Trop Med Hyg. 2017;97:826-830 pubmed publisher
    Plague is a fatal, primarily rodent-flea-borne zoonotic disease caused by Yersinia pestis...
  23. Boegler K, Atiku L, Enscore R, Apangu T, Mpanga J, Acayo S, et al. Rat Fall Surveillance Coupled with Vector Control and Community Education as a Plague Prevention Strategy in the West Nile Region, Uganda. Am J Trop Med Hyg. 2017;: pubmed publisher
    ..from 142 villages reported 580 small mammal deaths; 24 of these tested presumptive positive for Yersinia pestis by fluorescence microscopy...
  24. Findlay F, Proudfoot L, Stevens C, Barlow P. Cationic host defense peptides; novel antimicrobial therapeutics against Category A pathogens and emerging infections. Pathog Glob Health. 2016;110:137-47 pubmed publisher
    ..of Category A biological agents which include, but are not limited to; anthrax (Bacillus anthracis), plague (Yersinia pestis), smallpox (Variola major), tularemia (Francisella tularensis)...
  25. Brannon J, Burk D, Leclerc J, Thomassin J, Portt A, Berghuis A, et al. Inhibition of outer membrane proteases of the omptin family by aprotinin. Infect Immun. 2015;83:2300-11 pubmed publisher
    ..Importantly, aprotinin was able to inhibit not only CroP but also Yersinia pestis Pla and, to a lesser extent, E. coli OmpT...
  26. Achtman M. How old are bacterial pathogens?. Proc Biol Sci. 2016;283: pubmed publisher
    ..of genetic diversity and ancient DNA studies indicate that during the last 5000 years plague caused by Yersinia pestis has spread globally on multiple occasions from China and Central Asia...
  27. Sun Y, Jarrett C, Bosio C, Hinnebusch B. Retracing the evolutionary path that led to flea-borne transmission of Yersinia pestis. Cell Host Microbe. 2014;15:578-86 pubmed publisher
    b>Yersinia pestis is an arthropod-borne bacterial pathogen that evolved recently from Yersinia pseudotuberculosis, an enteric pathogen transmitted via the fecal-oral route...
  28. Quintard K, Dewitte A, Reboul A, Madec E, Bontemps Gallo S, Dondeyne J, et al. Evaluation of the Role of the opgGH Operon in Yersinia pseudotuberculosis and Its Deletion during the Emergence of Yersinia pestis. Infect Immun. 2015;83:3638-47 pubmed publisher
    ..OpgH also sequesters FtsZ in order to regulate cell size according to nutrient availability. Yersinia pestis (the agent of flea-borne plague) lost the opgGH operon during its emergence from the enteropathogen Yersinia ..
  29. Ritzert J, Lathem W. Depletion of Glucose Activates Catabolite Repression during Pneumonic Plague. J Bacteriol. 2018;200: pubmed publisher
    ..The plague-causing pathogen, Yersinia pestis, requires expression of the gene encoding the Pla protease for progression of pneumonic plague...
  30. Chung H, Yang E, Hwang D, Lee J, Guan Z, Raetz C. Kdo hydroxylase is an inner core assembly enzyme in the Ko-containing lipopolysaccharide biosynthesis. Biochem Biophys Res Commun. 2014;452:789-94 pubmed publisher
    ..The lipopolysaccharide (LPS) isolated from certain important Gram-negative pathogens including a human pathogen Yersinia pestis and opportunistic pathogens Burkholderia mallei and Burkholderia pseudomallei contains d-glycero-d-talo-oct-2-..
  31. Ford D, Joshua G, Wren B, Oyston P. The importance of the magnesium transporter MgtB for virulence of Yersinia pseudotuberculosis and Yersinia pestis. Microbiology. 2014;160:2710-7 pubmed publisher
    ..regulation via the PhoPQ two-component regulatory system for a range of Gram-negative bacteria, including Yersinia pestis and Yersinia pseudotuberculosis...
  32. Davis K, Isberg R. Plague's partners in crime. Immunity. 2014;41:347-349 pubmed publisher
    ..This frenzied inflammatory response to Yersinia pestis is poorly understood. In this issue of Immunity, St. John et al...
  33. Oteo J, Portillo A, Portero F, Zavala Castro J, Venzal J, Labruna M. 'Candidatus Rickettsia asemboensis' and Wolbachia spp. in Ctenocephalides felis and Pulex irritans fleas removed from dogs in Ecuador. Parasit Vectors. 2014;7:455 pubmed publisher
    ..irritans collected from animals in Ecuador. No fleas were found to be positive for any Bartonella species or Yersinia pestis. Clinicians should be aware of the potential risk of this new Candidatus Rickettsia sp...
  34. Ivashchenko T, Belova E, Dentovskaia S, Bel kova S, Balakhonov S, Ignatov S, et al. [Development and testing of an enzyme immunoassay-based monoclonal test system for the detection of the Yersinia pestis V antigen]. Prikl Biokhim Mikrobiol. 2014;50:211-8 pubmed
    ..The test system developed was able to detect the V antigen at concentrations as low as 2.0 ng/mL in cells of nine experimental Y. pestis cultures. The obtained preparation can be recommended for use in laboratory diagnostics of plaque. ..
  35. Merritt P, Nero T, Bohman L, Felek S, Krukonis E, Marketon M. Yersinia pestis targets neutrophils via complement receptor 3. Cell Microbiol. 2015;17:666-87 pubmed publisher
    ..Yet, the mechanism for target cell selection remains a mystery. Here we investigate the interaction of Yersinia pestis with murine splenocytes to identify factors that participate in the targeting process...
  36. Braun V, Helbig S, Patzer S, Pramanik A, Römer C. Import and export of bacterial protein toxins. Int J Med Microbiol. 2015;305:238-42 pubmed publisher
    ..of three investigated bacterial protein toxins, colicin M (Cma) of Escherichia coli, pesticin (Pst) of Yersinia pestis and hemolysin (ShlAB) of Serratia marcescens...
  37. Sivaraman V, Pechous R, Stasulli N, Eichelberger K, Miao E, Goldman W. Yersinia pestis activates both IL-1β and IL-1 receptor antagonist to modulate lung inflammation during pneumonic plague. PLoS Pathog. 2015;11:e1004688 pubmed publisher
    Pneumonic plague is the most rapid and lethal form of Yersinia pestis infection. Increasing evidence suggests that Y...
  38. Steed D, Liu J, Wasbrough E, Miller L, Halasohoris S, Miller J, et al. Origins of Yersinia pestis sensitivity to the arylomycin antibiotics and the inhibition of type I signal peptidase. Antimicrob Agents Chemother. 2015;59:3887-98 pubmed publisher
    b>Yersinia pestis is the etiologic agent of the plague. Reports of Y...
  39. Willias S, Chauhan S, Lo C, Chain P, Motin V. CRP-Mediated Carbon Catabolite Regulation of Yersinia pestis Biofilm Formation Is Enhanced by the Carbon Storage Regulator Protein, CsrA. PLoS ONE. 2015;10:e0135481 pubmed publisher
    The natural transmission of Yersinia pestis is reliant upon biofilm blockage of the flea vector. However, the environmentally-responsive adaptive regulators which facilitate Y...
  40. Li W, Wang S, Lu S. Pilot Study on the Use of DNA Priming Immunization to Enhance Y. pestis LcrV-Specific B Cell Responses Elicited by a Recombinant LcrV Protein Vaccine. Vaccines (Basel). 2013;2:36-48 pubmed publisher
    ..Plague is an acute and often fatal infectious disease caused by Yersinia pestis (Y. pestis). Humoral immune responses provide critical protective immunity against plague...
  41. Marsden A, King J, Spies M, Kim O, Yahr T. Inhibition of Pseudomonas aeruginosa ExsA DNA-Binding Activity by N-Hydroxybenzimidazoles. Antimicrob Agents Chemother. 2016;60:766-76 pubmed publisher
    ..ExsA homologs that control T3SS gene expression in Yersinia pestis, Aeromonas hydrophila, and Vibrio parahaemolyticus were also sensitive to N-hydroxybenzimidazoles...
  42. Mize E, Britten H. Detections of Yersinia pestis East of the Known Distribution of Active Plague in the United States. Vector Borne Zoonotic Dis. 2016;16:88-95 pubmed publisher
    ..units east of the known distribution of active plague across the northern Great Plains for the presence of Yersinia pestis. Across all national park units, Oropsylla tuberculata and Oropsylla hirsuta were the most common fleas ..
  43. Li Y, Li D, Shao H, Li H, Han Y. Plague in China 2014-All sporadic case report of pneumonic plague. BMC Infect Dis. 2016;16:85 pubmed publisher
    b>Yersinia pestis is the pathogen of the plague and caused three pandemics worldwide. Pneumonic plague is rarer than bubonic and septicemic plague...
  44. Spyrou M, Tukhbatova R, Feldman M, Drath J, Kacki S, Beltrán de Heredia J, et al. Historical Y. pestis Genomes Reveal the European Black Death as the Source of Ancient and Modern Plague Pandemics. Cell Host Microbe. 2016;19:874-81 pubmed publisher
    Ancient DNA analysis has revealed an involvement of the bacterial pathogen Yersinia pestis in several historical pandemics, including the second plague pandemic (Europe, mid-14(th) century Black Death until the mid-18(th) century AD)...
  45. Suntsov V. [Sympatric Speciation of the Plague Microbe Yersinia pestis: Monohostal Specialization in the Host-Parasite Marmot-Flea (Marmota sibirica-Oropsylla silantiewi) System]. Izv Akad Nauk Ser Biol. 2016;:117-27 pubmed
    ..The factors of the speciation process--isolation, the struggle for existence, and natural selection--were analyzed. ..
  46. Bland D, Jarrett C, Bosio C, Hinnebusch B. Infectious blood source alters early foregut infection and regurgitative transmission of Yersinia pestis by rodent fleas. PLoS Pathog. 2018;14:e1006859 pubmed publisher
    Fleas can transmit Yersinia pestis by two mechanisms, early-phase transmission (EPT) and biofilm-dependent transmission (BDT)...
  47. Gregg K, Harberts E, Gardner F, Pelletier M, Cayatte C, Yu L, et al. A lipid A-based TLR4 mimetic effectively adjuvants a Yersinia pestis rF-V1 subunit vaccine in a murine challenge model. Vaccine. 2018;36:4023-4031 pubmed publisher
    ..To evaluate the in vivo adjuvant activity of BECC438, we used the known protective Yersinia pestis (Yp) antigen, rF1-V, in a murine prime-boost vaccination schedule followed by lethal challenge...
  48. Palace S, Proulx M, Szabady R, Goguen J. Gain-of-Function Analysis Reveals Important Virulence Roles for the Yersinia pestis Type III Secretion System Effectors YopJ, YopT, and YpkA. Infect Immun. 2018;86: pubmed publisher
    Virulence of Yersinia pestis in mammals requires the type III secretion system, which delivers seven effector proteins into the cytoplasm of host cells to undermine immune responses...
  49. Lin A, Merkley E, Clowers B, Hutchison J, Kreuzer H. Effects of bacterial inactivation methods on downstream proteomic analysis. J Microbiol Methods. 2015;112:3-10 pubmed publisher
    ..To this end, we inactivated samples of Yersinia pestis and Escherichia coli by autoclave, ethanol, or irradiation treatment to determine how inactivation changes ..
  50. Osei Owusu P, Jessen Condry D, Toosky M, Roughead W, Bradley D, Nilles M. The N terminus of type III secretion needle protein YscF from Yersinia pestis functions to modulate innate immune responses. Infect Immun. 2015;83:1507-22 pubmed publisher
    ..The injectisome needle is formed by the polymerization of a single protein, e.g., YscF (Yersinia pestis), PscF (Pseudomonas aeruginosa), PrgI (Salmonella enterica SPI-1), SsaG (Salmonella enterica SPI-2), or MxiH (..
  51. Yang K, Park C, Cheong C, Bulgheresi S, Zhang S, Zhang P, et al. Host Langerin (CD207) is a receptor for Yersinia pestis phagocytosis and promotes dissemination. Immunol Cell Biol. 2015;93:815-24 pubmed publisher
    b>Yersinia pestis is a Gram-negative bacterium that causes plague. After Y. pestis overcomes the skin barrier, it encounters antigen-presenting cells (APCs), such as Langerhans and dendritic cells...
  52. Eddy J, Schroeder J, Zimbler D, Bellows L, Lathem W. Impact of the Pla protease substrate α2-antiplasmin on the progression of primary pneumonic plague. Infect Immun. 2015;83:4837-47 pubmed publisher
    Many pathogens usurp the host hemostatic system during infection to promote pathogenesis. Yersinia pestis, the causative agent of plague, expresses the plasminogen activator protease Pla, which has been shown in vitro to target and ..
  53. Haule M, Lyamuya E, Matee M, Kilonzo B, Hang Ombe B. Factors associated with flea infestation among the different rodent species in Mbulu and Karatu districts, northern Tanzania. Tanzan J Health Res. 2013;15:165-70 pubmed
    Flea infection with the bacterium, Yersinia pestis is acquired from reservoirs which include several rodents and other small mammals. In areas that are endemic of plague, reservoirs of Y...
  54. Häfner S, Fumi E. Perspectives of a Most Pestilent Past1. Microbes Infect. 2018;: pubmed publisher
    Article highlight based on "Bioluminescent tracing of a Yersinia pestis pCD1+-mutant and Yersinia pseudotuberculosis in subcutaneously infected mice" by Yazhou Zhou et al.
  55. Liu W, Tan Y, Cao S, Zhao H, Fang H, Yang X, et al. Protein Acetylation Mediated by YfiQ and CobB Is Involved in the Virulence and Stress Response of Yersinia pestis. Infect Immun. 2018;86: pubmed publisher
    ..coli and Salmonella However, little is known about protein acetylation modifications in Yersinia pestis, a lethal pathogen responsible for millions of human deaths in three worldwide pandemics...
  56. Danforth M, Tucker J, Novak M. The Deer Mouse (Peromyscus maniculatus) as an Enzootic Reservoir of Plague in California. Ecohealth. 2018;: pubmed publisher
    It has long been theorized that deer mice (Peromyscus maniculatus) are a primary reservoir of Yersinia pestis in California...
  57. Li C, Zhang P, Wang X, Liu X, Zhao Y, Sun C, et al. [Development and comparative evaluation of up-converting phosphor technology based lateral flow assay for rapid detection of Yersinia pestis, Bacillus anthracis spore and Brucella spp]. Zhonghua Yu Fang Yi Xue Za Zhi. 2015;49:3-8 pubmed
    ..up-converting phosphor technology based lateral flow (UPT-LF) assay for rapid and quantitative detection of Yersinia pestis, Bacillus anthracis spore and Brucella spp...
  58. Jones R, Borchert J, Eisen R, MacMillan K, Boegler K, Gage K. Flea-Associated Bacterial Communities across an Environmental Transect in a Plague-Endemic Region of Uganda. PLoS ONE. 2015;10:e0141057 pubmed publisher
    ..The primary route of transmission of Yersinia pestis, the causative agent of plague, is via flea bites...
  59. McCauley D, Salkeld D, Young H, Makundi R, Dirzo R, Eckerlin R, et al. Effects of land use on plague (Yersinia pestis) activity in rodents in Tanzania. Am J Trop Med Hyg. 2015;92:776-83 pubmed publisher
    ..Here, we compare prevalence of Yersinia pestis, the etiologic agent of plague, in rodents across two land-use types-agricultural and conserved-in northern ..
  60. Chaudhury S, Nordhues B, Kaur K, Zhang N, De Guzman R. Nuclear Magnetic Resonance Characterization of the Type III Secretion System Tip Chaperone Protein PcrG of Pseudomonas aeruginosa. Biochemistry. 2015;54:6576-85 pubmed publisher
    ..PcrG homologues are also important in the T3SS of other pathogens such as Yersinia pestis, the causative agent of bubonic plague...
  61. Souza Lopes A, Rodrigues J, Cabral A, da Silva M, Leal N, da Silveira V, et al. Occurrence and analysis of irp2 virulence gene in isolates of Klebsiella pneumoniae and Enterobacter spp. from microbiota and hospital and community-acquired infections. Microb Pathog. 2016;96:15-9 pubmed publisher
    ..sequences suggest the irp2 genes derived from isolates used in this study are more closely related to that of Yersinia pestis P.CE882 than to that of Yersinia enterocolitica 8081. These data demonstrated that K...
  62. Balakhonov S, Vityazeva S, Dubrovina V, Starovoitova T, Mukhturgin G, Ivanova T, et al. Immunogenesis in White Mice Infected with Yersinia pestis with Different Plasmid Composition. Bull Exp Biol Med. 2017;162:470-473 pubmed publisher
    ..Our findings allow considering Y. pestis subsp. altaica I-2948/3, Y. pestis subsp. pestis I-3479 and Y. pestis subsp. pestis I-3480 as promising candidates for vaccine strains. ..
  63. Shin C, Han J, Koh H, Choi B, Cho Y, Jeong H, et al. CD8α(-) Dendritic Cells Induce Antigen-Specific T Follicular Helper Cells Generating Efficient Humoral Immune Responses. Cell Rep. 2015;11:1929-40 pubmed publisher
    ..in significantly increased humoral immune responses against various human pathogenic antigens, including Yersinia pestis LcrV, HIV Gag, and hepatitis B surface antigen...
  64. Whittles L, Didelot X. Epidemiological analysis of the Eyam plague outbreak of 1665-1666. Proc Biol Sci. 2016;283: pubmed publisher
    Plague, caused by the bacterium Yersinia pestis, is one of the deadliest infectious diseases in human history, and still causes worrying outbreaks in Africa and South America...
  65. Cui Y, Song Y. Genome and Evolution of Yersinia pestis. Adv Exp Med Biol. 2016;918:171-192 pubmed
    This chapter summarizes researches on genome and evolution features of Yersinia pestis, the young pathogen that evolved from Y. pseudotuberculosis at least 5000 years ago. Y...
  66. Yang R, Cui Y, Bi Y. Perspectives on Yersinia pestis: A Model for Studying Zoonotic Pathogens. Adv Exp Med Biol. 2016;918:377-391 pubmed
    b>Yersinia pestis is a typical zoonotic bacterial pathogen. The following reasons make this pathogen a model for studying zoonotic pathogens: (1) Its unique lifestyle makes Y...
  67. Dutour O. Paleoparasitology and paleopathology. Synergies for reconstructing the past of human infectious diseases and their pathocenosis. Int J Paleopathol. 2013;3:145-149 pubmed publisher
    ..has mainly been applied to bacterial pathogens, such as Mycobacterium tuberculosis, Mycobacterium leprae, Yersinia pestis, Rickettsia prowazecki and Bartonella quintana, due to the fact that anthropologists and paleopathologists ..
  68. Perry R, Bobrov A, Fetherston J. The role of transition metal transporters for iron, zinc, manganese, and copper in the pathogenesis of Yersinia pestis. Metallomics. 2015;7:965-78 pubmed publisher
    b>Yersinia pestis, the causative agent of bubonic, septicemic and pneumonic plague, encodes a multitude of Fe transport systems...
  69. Zhang Y, Dai X, Wang Q, Chen H, Meng W, Wu K, et al. Transmission efficiency of the plague pathogen (Y. pestis) by the flea, Xenopsylla skrjabini, to mice and great gerbils. Parasit Vectors. 2015;8:256 pubmed publisher
    Plague, a zoonotic disease caused by Yersinia pestis, is characterized by its ability to persist in the plague natural foci...
  70. Zhu H, Mao X, Guo X, Sun Y. The hmsT 3' untranslated region mediates c-di-GMP metabolism and biofilm formation in Yersinia pestis. Mol Microbiol. 2016;99:1167-78 pubmed publisher
    b>Yersinia pestis, the cause of plague, forms a biofilm in the proventriculus of its flea vector to enhance transmission. Biofilm formation in Y. pestis is regulated by the intracellular levels of cyclic diguanylate (c-di-GMP)...
  71. Henderson T, Nilles M. Blue Native Protein Electrophoresis to Study the T3S System Using Yersinia pestis as a Model. Methods Mol Biol. 2017;1531:33-46 pubmed
    ..was determined in a study described here of protein complexes identified in the plague causing bacteria, Yersinia pestis. In addition, the technique was used to observe how LcrG, a negative regulator of the pathogenic Type III ..
  72. Maleki Ravasan N, Solhjouy Fard S, Beaucournu J, Laudisoit A, Mostafavi E. The Fleas (Siphonaptera) in Iran: Diversity, Host Range, and Medical Importance. PLoS Negl Trop Dis. 2017;11:e0005260 pubmed publisher
    ..g. Yersinia pestis, Francisella tularensis, and Rickettsia felis) are necessary tools for controlling and preventing such ..
  73. Hoe N, Minion F, Goguen J. Temperature sensing in Yersinia pestis: regulation of yopE transcription by lcrF. J Bacteriol. 1992;174:4275-86 pubmed
    ..yopE::lacZ fusion was found to be regulated by temperature in the presence of the cloned BamHI G fragment of Yersinia pestis plasmid pCD1, which contains the lcrF locus...
  74. Wang M, Tang X, Wang Z. [PCR-derived technology in gene identification and typing of Yersinia pestis]. Zhonghua Yu Fang Yi Xue Za Zhi. 2015;49:75-7 pubmed
    Application of the PCR-derived technology in gene identification and genotypes of different ecotype Yersinia pestis to make the high-throughput experimental results can reflect the epidemic history and compare the diversity in genome, ..
  75. Read T, Olkhov R, Williamson E, Shaw A. Label-free Fab and Fc affinity/avidity profiling of the antibody complex half-life for polyclonal and monoclonal efficacy screening. Anal Bioanal Chem. 2015;407:7349-57 pubmed publisher
    ..3, 12.3, 29.3, 36.3 and 46.3 raised against LcrV in Yersinia pestis. The rate of the dissociation of antigen-antibody complexes relates directly to their immunological function ..
  76. Han Y, Fang H, Liu L, Zhou D. Genetic Regulation of Yersinia pestis. Adv Exp Med Biol. 2016;918:223-256 pubmed
    ..pestis. ..
  77. Gut I, Bartlett R, Yeager J, Leroux B, Ratnesar Shumate S, Dabisch P, et al. Extraction of Aerosol-Deposited Yersinia pestis from Indoor Surfaces To Determine Bacterial Environmental Decay. Appl Environ Microbiol. 2016;82:2809-2818 pubmed publisher
    ..To demonstrate the usefulness of the system for decay studies,Yersinia pestis persistence as a function of surface type at 21 °C and 40% RH was determined to be >40%/min for all ..
  78. Raoult D. A Personal View of How Paleomicrobiology Aids Our Understanding of the Role of Lice in Plague Pandemics. Microbiol Spectr. 2016;4: pubmed publisher
    We have been involved in the field of paleomicrobiology since 1998, when we used dental pulp to identify Yersinia pestis as the causative agent of the great plague of Marseille (1720)...
  79. van Lier C, Tiner B, Chauhan S, Motin V, Fitts E, Huante M, et al. Further characterization of a highly attenuated Yersinia pestis CO92 mutant deleted for the genes encoding Braun lipoprotein and plasminogen activator protease in murine alveolar and primary human macrophages. Microb Pathog. 2015;80:27-38 pubmed publisher
    We recently characterized the Δlpp Δpla double in-frame deletion mutant of Yersinia pestis CO92 molecularly, biologically, and immunologically...
  80. Shi G, Zhang Z, Mei L, Chen J, Mei S, Jin D, et al. [Establishment and evaluation of identification method for Yersinia pestis and Yersinia pseudotuberculosis]. Zhonghua Liu Xing Bing Xue Za Zhi. 2015;36:496-500 pubmed
    To establish a gene identification method of Yersinia pestis and Yersinia pseudotuberculosis for plague surveillance. According to the specific genomic sequences of Y. pestis and Y. pseudotuberculosis, i.e...
  81. Feodorova V, Sayapina L, Motin V. Assessment of Live Plague Vaccine Candidates. Methods Mol Biol. 2016;1403:487-98 pubmed publisher
    ..in developing subunit vaccines, there is a reviving interest in creation of a precisely attenuated strain of Yersinia pestis superior to the EV that can serve as a live plague vaccine with improved characteristics...
  82. Johnson T, Hinnebusch B, Boegler K, Graham C, MacMillan K, Montenieri J, et al. Yersinia murine toxin is not required for early-phase transmission of Yersinia pestis by Oropsylla montana (Siphonaptera: Ceratophyllidae) or Xenopsylla cheopis (Siphonaptera: Pulicidae). Microbiology. 2014;160:2517-25 pubmed publisher
    Plague, caused by Yersinia pestis, is characterized by quiescent periods punctuated by rapidly spreading epizootics...
  83. Wei B, Xiong H, Yang X, Yang Y, Qi M, Jin J, et al. [The epidemiology and etiology research of Tibetan sheep plague in Qinghai plateau]. Zhonghua Liu Xing Bing Xue Za Zhi. 2015;36:271-4 pubmed
    ..infection routes, ecological factors for the spread were used to analyze; followed by choosing 14 Yersinia pestis strains isolated from such sheep for biochemical test, toxicity test, virulence factors identification, ..
  84. Keasey S, Natesan M, Pugh C, Kamata T, Wuchty S, Ulrich R. Cell-free Determination of Binary Complexes That Comprise Extended Protein-Protein Interaction Networks of Yersinia pestis. Mol Cell Proteomics. 2016;15:3220-3232 pubmed
    ..We used a library of recombinant proteins from the plague bacterium Yersinia pestis to probe planar microarrays of immobilized proteins that represented ?85% (3552 proteins) of the bacterial ..
  85. Bennett V, McNevin D, Roffey P, Gahan M. Characterization of Yersinia species by protein profiling using automated microfluidic capillary electrophoresis. Forensic Sci Med Pathol. 2017;13:10-19 pubmed publisher
    b>Yersinia pestis is a biological agent of high risk to national security due to its ability to be easily disseminated and transmitted among humans. If Y...
  86. Avril A. Therapeutic Antibodies for Biodefense. Adv Exp Med Biol. 2017;1053:173-205 pubmed publisher
    ..B and C); Category A consists of the six pathogens most suitable for use as bioweapons (Bacillus anthracis, Yersinia pestis, Francisella tularensis, botulinum neurotoxins, smallpox and viral hemorrhagic fevers)...
  87. Revazishvili T, Johnson J. Pulsed-field gel electrophoresis of Yersinia pestis. Methods Mol Biol. 2015;1301:115-28 pubmed publisher
    b>Yersinia pestis is a human pathogen and can cause serious disease. Biosafety level 3 (BSL3) is required when handling this microorganism and all work requires a biological safety cabinet...
  88. Gonzalez R, Miller V. A Deadly Path: Bacterial Spread During Bubonic Plague. Trends Microbiol. 2016;24:239-241 pubmed publisher
    b>Yersinia pestis causes bubonic plague, a fulminant disease where host immune responses are abrogated. Recently developed in vivo models of plague have resulted in new ideas regarding bacterial spread in the body...
  89. Demeure C, Derbise A, Carniel E. Oral vaccination against plague using Yersinia pseudotuberculosis. Chem Biol Interact. 2017;267:89-95 pubmed publisher
    b>Yersinia pestis, the agent of plague, is among the deadliest bacterial pathogens affecting humans, and is a potential biological weapon...
  90. Lasch P, Wahab T, Weil S, Pályi B, Tomaso H, Zange S, et al. Identification of Highly Pathogenic Microorganisms by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry: Results of an Interlaboratory Ring Trial. J Clin Microbiol. 2015;53:2632-40 pubmed publisher
    ..among them five HPB, Bacillus anthracis, Brucella canis, Burkholderia mallei, Burkholderia pseudomallei, and Yersinia pestis, were characterized under blinded conditions...
  91. Tsang T, Wiese J, Alhabeil J, Usselman L, Thomson J, Matti R, et al. Defining the Ail Ligand-Binding Surface: Hydrophobic Residues in Two Extracellular Loops Mediate Cell and Extracellular Matrix Binding To Facilitate Yop Delivery. Infect Immun. 2017;85: pubmed publisher
    i>Yersinia pestis, the causative agent of plague, binds host cells to deliver cytotoxic Yop proteins into the cytoplasm that prevent phagocytosis and generation of proinflammatory cytokines...
  92. Cherepanov P, Mikhailova T, Karimova G, Zakharova N, Ershov I, Volkovoĭ K. [Cloning and detailed mapping of the fra-ymt region of the Yersinia pestis pFra plasmid]. Mol Gen Mikrobiol Virusol. 1991;:19-26 pubmed
    The genetical libraries of the pFra plasmid of Yersinia pestis genes were obtained by insertion into the PstI, SalGI, EcoRI, XhoI restriction sites of the cosmid vector pHC79...