Shigella flexneri

Summary

Alias: "Shigella paradysenteriae" Weldin 1927, Shigella flexneri Castellani and Chalmers 1919, Shigella paradysenteriae

Top Publications

  1. Assob J, Kamga H, Nsagha D, Njunda A, Nde P, Asongalem E, et al. Antimicrobial and toxicological activities of five medicinal plant species from Cameroon traditional medicine. BMC Complement Altern Med. 2011;11:70 pubmed publisher
    ..and six Gram negative (Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Proteus mirabilis, Shigella flexneri, Salmonella typhi) and two fungal isolates (Candida albicans, Candida krusei)...
  2. Arunachalam K, Ascêncio S, Soares I, Souza Aguiar R, da Silva L, de Oliveira R, et al. Gallesia integrifolia (Spreng.) Harms: In vitro and in vivo antibacterial activities and mode of action. J Ethnopharmacol. 2016;184:128-37 pubmed publisher
    ..entry of hydrophobic antibiotic in Pseudomonas aeruginosa, intense K(+) efflux and nucleotides leakage in Shigella flexneri, Streptococcus pyogenes and S. aureus. HEGi attenuated the experimental blood borne S...
  3. Tanapichatsakul C, Monggoot S, Gentekaki E, Pripdeevech P. Antibacterial and Antioxidant Metabolites of Diaporthe spp. Isolated from Flowers of Melodorum fruticosum. Curr Microbiol. 2018;75:476-483 pubmed publisher
    ..cereus, Klebsiella pneumoniae, Pseudomonas aeruginosa, Escherichia coli, Shigella flexneri, Vibrio cholerae and V. parahaemolyticus...
  4. Mitchison M, Bulach D, Vinh T, Rajakumar K, Faine S, Adler B. Identification and characterization of the dTDP-rhamnose biosynthesis and transfer genes of the lipopolysaccharide-related rfb locus in Leptospira interrogans serovar Copenhageni. J Bacteriol. 1997;179:1262-7 pubmed
    ..coli, and Shigella flexneri. An additional open reading frame downstream of the rfbCDBA locus showed similarity with the ..
  5. Li X, Harwood V, Nayak B, Weidhaas J. Ultrafiltration and Microarray for Detection of Microbial Source Tracking Marker and Pathogen Genes in Riverine and Marine Systems. Appl Environ Microbiol. 2016;82:1625-1635 pubmed publisher
    ..Pathogens such as Legionella pneumophila, Shigella flexneri, and Campylobacter fetus were detected along with genes conferring resistance to aminoglycosides, beta-..
  6. Marimuthu K, Gunaselvam P, Aminur Rahman M, Xavier R, Arockiaraj J, Subramanian S, et al. Antibacterial activity of ovary extract from sea urchin Diadema setosum. Eur Rev Med Pharmacol Sci. 2015;19:1895-9 pubmed
    ..species using the disc diffusion method: Gram-negative bacteria (Salmonella typhi, Salmonella typhimurium, Shigella flexneri, Pseudomonas aeruginosa, Aeromonas hydrophila, Acinetobacter sp, Citrobacter freundii and Klebsiella ..
  7. de Brito M, Peláez W, Faillace M, Militão G, Almeida J, Argüello G, et al. Cyclohexene-fused 1,3-oxazines with selective antibacterial and antiparasitic action and low cytotoxic effects. Toxicol In Vitro. 2017;44:273-279 pubmed publisher
    ..Enterococcus faecalis, Escherichia coli, Klebsiella pneumoniae, Salmonella enterica, Serratia marcescens, Shigella flexneri and Staphylococcus aureus by the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal ..
  8. Sharma C, Singh B, Thakur N, Gulati S, Gupta S, Mishra S, et al. Antibacterial effects of Lactobacillus isolates of curd and human milk origin against food-borne and human pathogens. 3 Biotech. 2017;7:31 pubmed publisher
    ..Bacillus cereus, Salmonella enterica serovar Typhi, and Shigella flexneri were moderately inhibited by majority of CFSs, whereas, weak activity was observed against Pseudomonas ..
  9. Hernández García E, Garcia A, Garza Gonzalez E, Avalos Alanís F, Rivas Galindo V, Rodriguez Rodriguez J, et al. Chemical composition of Acacia farnesiana (L) wild fruits and its activity against Mycobacterium tuberculosis and dysentery bacteria. J Ethnopharmacol. 2019;230:74-80 pubmed publisher
    ..against Mycobacterium tuberculosis H37Rv and G122 as well as dysentery bacteria (Campylobacter jejuni, Shigella flexneri, Salmonella enteritidis, Yersinia enterocolitica and enterohemorrhagic Escherichia coli) was determined by ..

More Information

Publications244 found, 100 shown here

  1. Dutta S, Jain P, Nandy S, Matsushita S, Yoshida S. Molecular characterization of serologically atypical provisional serovars of Shigella isolates from Kolkata, India. J Med Microbiol. 2014;63:1696-703 pubmed publisher
    ..serovar I9809-73 (n = 1), Shigella dysenteriae provisional serovar 93-119 (n = 1), Shigella flexneri provisional serovar 88-893 (n = 6) and Shigella boydii provisional serovar E16553 (n =â€..
  2. Karthik K, Dhanuskodi S, Gobinath C, Prabukumar S, Sivaramakrishnan S. Fabrication of MgO nanostructures and its efficient photocatalytic, antibacterial and anticancer performance. J Photochem Photobiol B. 2019;190:8-20 pubmed publisher
    ..The antibacterial activities of M 1 and M 2 are investigated against the gram-negative (Escherichia coli, Shigella flexneri, Salmonella typhi, Proteus mirabilis, Aeromonas hydrophila and Vibrio cholera) and gram-positive (Bacillus ..
  3. Seo J, Go H, Kim C, Nam B, Park N. Antimicrobial peptide, hdMolluscidin, purified from the gill of the abalone, Haliotis discus. Fish Shellfish Immunol. 2016;52:289-97 pubmed publisher
    ..bacteria including Aeromonas hydrophila, Escherichia coli, Pseudomonas aeruginosa, Salmonella enterica, Shigella flexneri, and Vibrio parahemolyticus ([MECs]; 1.0-4.0 ?g/mL) without hemolytic activity...
  4. Mitobe J, Sinha R, Mitra S, Nag D, Saito N, Shimuta K, et al. An attenuated Shigella mutant lacking the RNA-binding protein Hfq provides cross-protection against Shigella strains of broad serotype. PLoS Negl Trop Dis. 2017;11:e0005728 pubmed publisher
    ..Here, immunization with a mutant of Shigella flexneri 2a protected guinea pigs against subsequent infection by S. dysenteriae type 1 and S. sonnei strains...
  5. Shakya G, Acharya J, Adhikari S, Rijal N. Shigellosis in Nepal: 13 years review of nationwide surveillance. J Health Popul Nutr. 2016;35:36 pubmed
    ..A total of 332 isolates were identified as Shigella species of which Shigella flexneri (50 %) was the predominant serotype...
  6. Gupta A, Tiwari S, Netrebov V, Chikindas M. Biochemical Properties and Mechanism of Action of Enterocin LD3 Purified from Enterococcus hirae LD3. Probiotics Antimicrob Proteins. 2016;8:161-9 pubmed publisher
    ..pathogens such as Staphylococcus aureus, Pseudomonas fluorescens, Pseudomonas aeruginosa, Salmonella typhi, Shigella flexneri, Listeria monocytogenes, Escherichia coli O157:H7, E. coli (urogenic, a clinical isolate) and Vibrio sp...
  7. Noshad M, Hojjati M, Alizadeh Behbahani B. Black Zira essential oil: Chemical compositions and antimicrobial activity against the growth of some pathogenic strain causing infection. Microb Pathog. 2018;116:153-157 pubmed publisher
    ..of Black Zira essential oil against Enterobacter aerogenes, Pseudomonas aeruginosa, Escherichia coli, Shigella flexneri, Staphylococcus epidermidis, Streptococcus pyogenes and Candida albicans...
  8. Haddar C, Begaud E, Maslin J, Germani Y. [Point-of-care tests for the rapid diagnosis of shigellosis]. Bull Soc Pathol Exot. 2017;110:1-8 pubmed publisher
    ..b>Shigella flexneri 2a, Shigella sonnei, and Shigella dysenteriae 1...
  9. Liu H, Zhang L, Yi H, Han X, Gao W, Chi C, et al. A novel enterocin T1 with anti-Pseudomonas activity produced by Enterococcus faecium T1 from Chinese Tibet cheese. World J Microbiol Biotechnol. 2016;32:21 pubmed publisher
    ..putida, Pseudomonas aeruginosa, Pseudomonas fluorescens, Escherichia coli, Salmonella typhimurium, Shigella flexneri, Shigella sonnei, Staphylococcus aureus, Listeria monocytogenes...
  10. Karimaei S, Sadeghi J, Asadian M, Esghaei M, Pourshafie M, Talebi M. Antibacterial potential and genetic profile of Enterococcus faecium strains isolated from human normal flora. Microb Pathog. 2016;96:67-71 pubmed publisher
    ..These isolates were investigated further to examine their ability to inhibit growth of Salmonella typhi, Shigella flexneri and Escherichia coli by well diffusion assay...
  11. Bisi Johnson M, Obi C, Samuel B, Eloff J, Okoh A. Antibacterial activity of crude extracts of some South African medicinal plants against multidrug resistant etiological agents of diarrhoea. BMC Complement Altern Med. 2017;17:321 pubmed publisher
    ..typhi, S. enterica serovar Typhimurium, Shigella flexneri type 1b and Sh. sonnei phase II...
  12. Chen S, Chen L, Chen L, Ren X, Ge H, Li B, et al. Potential probiotic characterization of Lactobacillus reuteri from traditional Chinese highland barley wine and application for room-temperature-storage drinkable yogurt. J Dairy Sci. 2018;101:5780-5788 pubmed publisher
    ..tract, including strong adherence to HT-29 cells and inhibitory activity against Escherichia coli, Shigella flexneri, Salmonella paratyphi β, and Staphylococcus aureus...
  13. Gray M, Lacher D, Leonard S, Abbott J, Zhao S, Lampel K, et al. Prevalence of Shiga toxin-producing Shigella species isolated from French travellers returning from the Caribbean: an emerging pathogen with international implications. Clin Microbiol Infect. 2015;21:765.e9-765.e14 pubmed publisher
    ..We recently reported the presence and expression of stx genes in Shigella flexneri 2a clinical isolates...
  14. Maharjan S, Rayamajhee B, Shreshtha A, Acharya J. Serotyping and antibiotic susceptibility patterns of Vibrio and Shigella isolates from diarrheal patients visiting a Tropical and Infectious Diseases Hospital in central Nepal. BMC Res Notes. 2017;10:626 pubmed publisher
    ..6%). All V. cholerae strains belonged to the serogroup O1 and serovar Ogawa. Among the Shigella spp., Shigella flexneri 17 (59%) topped the list of serotype followed by Shigella sonnei 8 (28%), Shigella dysenteriae 3 (10%) and ..
  15. Cao Z, Pan H, Li S, Shi C, Wang S, Wang F, et al. In Vitro Evaluation of Probiotic Potential of Lactic Acid Bacteria Isolated from Yunnan De'ang Pickled Tea. Probiotics Antimicrob Proteins. 2019;11:103-112 pubmed publisher
    ..In contrast, eight out of the 18 strains suppressed growth of Shigella flexneri. Two L...
  16. Dahl M, Manson M. Interspecific reconstitution of maltose transport and chemotaxis in Escherichia coli with maltose-binding protein from various enteric bacteria. J Bacteriol. 1985;164:1057-63 pubmed
    ..coli protein and had a similar molecular weight (about 40,000). The Shigella flexneri and Proteus mirabilis strains we examined did not synthesize MBP...
  17. Mukherjee R, Patra M, Dutta D, Banik M, Basu T. Tetracycline-loaded calcium phosphate nanoparticle (Tet-CPNP): Rejuvenation of an obsolete antibiotic to further action. Biochim Biophys Acta. 2016;1860:1929-41 pubmed publisher
    ..antibiotic (including tetracycline) resistant bacteria like Escherichia coli, Salmonella kentuckey and Shigella flexneri was in the range of 20-40?g/ml, whereas MIC of free tetracycline was in the range of 150-180?g/ml...
  18. Eichner M, Protze J, Piontek A, Krause G, Piontek J. Targeting and alteration of tight junctions by bacteria and their virulence factors such as Clostridium perfringens enterotoxin. Pflugers Arch. 2017;469:77-90 pubmed publisher
    ..perfringens, Escherichia coli, Helicobacter pylori, Salmonella typhimurium, Shigella flexneri, Vibrio cholerae, Yersinia enterocolitica, protozoan parasites, and their proteins...
  19. Sváb D, Bálint B, Vásárhelyi B, Maróti G, Tóth I. Comparative Genomic and Phylogenetic Analysis of a Shiga Toxin Producing Shigella sonnei (STSS) Strain. Front Cell Infect Microbiol. 2017;7:229 pubmed publisher
    ..More recently, several S. sonnei and Shigella flexneri strains producing Shiga toxin (Stx) have been reported from sporadic cases and from an outbreak in ..
  20. Pinaud L, Ferrari M, Friedman R, Jehmlich N, von Bergen M, Phalipon A, et al. Identification of novel substrates of Shigella T3SA through analysis of its virulence plasmid-encoded secretome. PLoS ONE. 2017;12:e0186920 pubmed publisher
    ..Indeed, sequencing of the virulence plasmid of Shigella flexneri has revealed numerous open reading frames with unknown functions that could encode additional T3SA ..
  21. Ahmed A, Shimamoto T. Molecular characterization of multidrug-resistant Shigella spp. of food origin. Int J Food Microbiol. 2015;194:78-82 pubmed publisher
    ..The multidrug-resistant Shigella spp. were as follows: Shigella flexneri (66.7%), Shigella sonnei (18.5%), and Shigella dysenteriae (3.7%)...
  22. Fakruddin M, Rahaman M, Ahmed M, Hoque M. Stress tolerant virulent strains of Cronobacter sakazakii from food. Biol Res. 2014;47:63 pubmed publisher
    ..Shigella boydii, Shigella sonnei, Shigella flexneri and Vibrio cholerae. They had significant tolerance to high temperature, low pH, dryness and osmotic stress...
  23. Gao Y, Li B, Li D, Zhang L. Purification and characteristics of a novel bacteriocin produced by Enterococcus faecalis L11 isolated from Chinese traditional fermented cucumber. Biotechnol Lett. 2016;38:871-6 pubmed publisher
    ..coli and Shigella flexneri. Enterocin L11 retained 91 % of its activity after holding at 121 °C for 30 min...
  24. Barbier M, Damron F. Rainbow Vectors for Broad-Range Bacterial Fluorescence Labeling. PLoS ONE. 2016;11:e0146827 pubmed publisher
    ..including Escherichia coli, Pseudomonas aeruginosa, Burkholderia cepacia, Bordetella bronchiseptica, Shigella flexneri or Klebsiella pneumoniae...
  25. Muraleedharan C, Talreja D, Kanwar M, Kumar A, Walia S. Occurrence of extended-spectrum β-lactamase-producing bacteria in urban Clinton River habitat. J Glob Antimicrob Resist. 2018;16:225-235 pubmed publisher
    ..16S rRNA analysis of water samples showed the presence of potentially pathogenic bacteria (e.g. Shigella flexneri, Klebsiella pneumoniae, Aeromonas punctata and Pseudomonas aeruginosa)...
  26. Ta A, Thakur B, Dutta P, Sinha R, Koley H, Das S. Double-stranded RNA induces cathelicidin expression in the intestinal epithelial cells through phosphatidylinositol 3-kinase-protein kinase C?-Sp1 pathway and ameliorates shigellosis in mice. Cell Signal. 2017;35:140-153 pubmed publisher
    ..poly(I:C) administration in mice reduces intestinal bacterial load and mucosal inflammation following Shigella flexneri 2a infection by inducing mCRAMP expression in the colonic epithelial cells...
  27. Corona Castañeda B, Rosas Ramírez D, Castañeda Gómez J, Aparicio Cuevas M, Fragoso Serrano M, Figueroa González G, et al. Resin glycosides from Ipomoea wolcottiana as modulators of the multidrug resistance phenotype in vitro. Phytochemistry. 2016;123:48-57 pubmed publisher
    ..strains of Escherichia coli, and two nosocomial pathogens: Salmonella enterica serovar Typhi and Shigella flexneri; however, when tested (25 μg/mL) in combination with tetracycline, kanamycin or chloramphenicol, they ..
  28. Xavier J, Babusha S, George J, Ramana K. Material Properties and Antimicrobial Activity of Polyhydroxybutyrate (PHB) Films Incorporated with Vanillin. Appl Biochem Biotechnol. 2015;176:1498-510 pubmed publisher
    ..against foodborne pathogens and spoilage bacteria comprising of Escherichia coli, Salmonella typhimurium, Shigella flexneri, and Staphylococcus aureus and fungi such as Aspergillus flavus, Aspergillus fumigatus, Aspergillus niger, ..
  29. Fritah S, Lhocine N, Golebiowski F, Mounier J, Andrieux A, Jouvion G, et al. Sumoylation controls host anti-bacterial response to the gut invasive pathogen Shigella flexneri. EMBO Rep. 2014;15:965-72 pubmed publisher
    b>Shigella flexneri, the etiological agent of bacillary dysentery, invades the human colonic epithelium and causes its massive inflammatory destruction...
  30. Kämpf M, Braun M, Sirena D, Ihssen J, Thöny Meyer L, Ren Q. In vivo production of a novel glycoconjugate vaccine against Shigella flexneri 2a in recombinant Escherichia coli: identification of stimulating factors for in vivo glycosylation. Microb Cell Fact. 2015;14:12 pubmed publisher
    ..In this study, we report on the production of a new recombinant glycoconjugate vaccine against Shigella flexneri 2a representing the major serotype for global outbreaks of shigellosis. We demonstrate that S...
  31. Gazoni V, Balogun S, Arunachalam K, Oliveira D, Filho V, Lima S, et al. Assessment of toxicity and differential antimicrobial activity of methanol extract of rhizome of Simaba ferruginea A. St.-Hil. and its isolate canthin-6-one. J Ethnopharmacol. 2018;223:122-134 pubmed publisher
    ..5 μg/mL) and Escherichia coli (MIC 25 μg/mL) and moderate activity against Enterococcus faecalis and Shigella flexneri (MIC 200 μg/mL) but no antifungal effect...
  32. Pu X, Gu Y, Li J, Song S, Lu Z. Characterization of the complete sequences and stability of plasmids carrying the genes aac(6')-Ib-cr or qnrS in Shigella flexneri in the Hangzhou area of China. World J Microbiol Biotechnol. 2018;34:72 pubmed publisher
    ..When the plasmids were electroporated into Shigella flexneri or they lost positive plasmids, the MICs of ciprofloxacin increased or decreased two- to eightfold for aac(6'..
  33. Abrusci P, Vergara Irigaray M, Johnson S, Beeby M, Hendrixson D, Roversi P, et al. Architecture of the major component of the type III secretion system export apparatus. Nat Struct Mol Biol. 2013;20:99-104 pubmed publisher
    ..We show that a key member of the Shigella flexneri export apparatus, MxiA, assembles into a ring essential for secretion in vivo...
  34. Gray M, Lampel K, Strockbine N, Fernández R, Melton Celsa A, Maurelli A. Clinical isolates of Shiga toxin 1a-producing Shigella flexneri with an epidemiological link to recent travel to Hispañiola. Emerg Infect Dis. 2014;20:1669-77 pubmed publisher
    ..We identified 26 Shigella flexneri serotype 2 strains isolated by public health laboratories in the United States during 2001-2013, which ..
  35. Mikulic J, Bioley G, Corthesy B. SIgA-Shigella Immune Complexes Interact with Dectin-1 and SIGNR3 to Differentially Regulate Mouse Peyer's Patch and Mesenteric Lymph Node Dendritic Cell's Responsiveness. J Mol Biol. 2017;429:2387-2400 pubmed publisher
    ..We find that in comparison with incubation of Shigella flexneri alone, association of the enteropathogen with SIgA prompts freshly isolated DCs from PPs and MLNs to invert ..
  36. Wang Y, Gong G, Zhou W, Zhang B, Bao S, Wei C, et al. Analysis on the interaction domain of VirG and apyrase by pull-down assay. Molecules. 2014;19:18090-101 pubmed publisher
    ..v53-758, v759-1102, v53-319, v320-507, v507-758) by denaturation-renaturation, the phoN2:kan mutant of Shigella flexneri 5a M90T by a modified version of the lambda red recombination protocol originally described by Datsenko and ..
  37. Demers J, Habenstein B, Loquet A, Kumar Vasa S, Giller K, Becker S, et al. High-resolution structure of the Shigella type-III secretion needle by solid-state NMR and cryo-electron microscopy. Nat Commun. 2014;5:4976 pubmed publisher
    ..density map and 996 ssNMR distance constraints, the structure of the type-III secretion system needle of Shigella flexneri is determined to a precision of 0.4 Å...
  38. Tamanna -, Ramana J. Structural Insights into the Fluoroquinolone Resistance Mechanism of Shigella flexneri DNA Gyrase and Topoisomerase IV. Microb Drug Resist. 2016;22:404-11 pubmed publisher
    ..In this work, we performed docking studies of DNA gyraseA (GyrA) and topoisomerase IV (ParC) of Shigella flexneri and their mutants with two different fluoroquinolones, ciprofloxacin and norfloxacin, to understand their ..
  39. Sorbara M, Foerster E, Tsalikis J, Abdel Nour M, Mangiapane J, Sirluck Schroeder I, et al. Complement C3 Drives Autophagy-Dependent Restriction of Cyto-invasive Bacteria. Cell Host Microbe. 2018;23:644-652.e5 pubmed publisher
    ..In contrast, Shigella flexneri and Salmonella Typhimurium escape autophagy-mediated growth restriction in part through the action of ..
  40. Campbell Valois F, Sachse M, Sansonetti P, Parsot C. Escape of Actively Secreting Shigella flexneri from ATG8/LC3-Positive Vacuoles Formed during Cell-To-Cell Spread Is Facilitated by IcsB and VirA. MBio. 2015;6:e02567-14 pubmed publisher
    The enteropathogenic bacterium Shigella flexneri uses a type 3 secretion apparatus (T3SA) to transfer proteins dubbed translocators and effectors inside host cells, inducing bacterial uptake and subsequent lysis of the entry vacuole...
  41. Lobato Márquez D, Krokowski S, Sirianni A, Larrouy Maumus G, Mostowy S. A requirement for septins and the autophagy receptor p62 in the proliferation of intracellular Shigella. Cytoskeleton (Hoboken). 2018;: pubmed publisher
    b>Shigella flexneri, a Gram-negative enteroinvasive pathogen, causes inflammatory destruction of the human intestinal epithelium...
  42. Fogolari M, Mavian C, Angeletti S, Salemi M, Lampel K, Maurelli A. Distribution and characterization of Shiga toxin converting temperate phages carried by Shigella flexneri in Hispaniola. Infect Genet Evol. 2018;65:321-328 pubmed publisher
    ..dysenteriae type 1 Shigella species, such as S. flexneri, spans not only the basic science behind horizontal phage spread, but also extends to medical treatment of patients infected with this pathogen. ..
  43. Chen Y, Liu L, Fu H, Wei C, Jin Q. Comparative proteomic analysis of outer membrane vesicles from Shigella flexneri under different culture conditions. Biochem Biophys Res Commun. 2014;453:696-702 pubmed publisher
    ..Nonetheless, the processes of Shigella flexneri OMV production still remain unclear. S...
  44. Tripler T, Teschke C, Alexandrescu A. NMR assignments for the insertion domain of bacteriophage Sf6 coat protein. Biomol NMR Assign. 2017;11:35-38 pubmed publisher
    ..Sf6 is a phage that infects the human pathogen Shigella flexneri. The coat protein of Sf6 assembles into a procapsid, which further undergoes maturation during DNA packaging ..
  45. Shahin K, Bouzari M, Wang R. Isolation, characterization and genomic analysis of a novel lytic bacteriophage vB_SsoS-ISF002 infecting Shigella sonnei and Shigella flexneri. J Med Microbiol. 2018;67:376-386 pubmed publisher
    ..from urban wastewater in Iran and showed infectivity to different isolates of both Shigella sonnei and Shigella flexneri. vB_SsoS-ISF002 was stable at different pH values and temperatures...
  46. Liang B, Roberts A, Xu X, Yang C, Yang X, Wang J, et al. Transferable Plasmid-Borne mcr-1 in a Colistin-Resistant Shigella flexneri Isolate. Appl Environ Microbiol. 2018;84: pubmed publisher
    ..rarely reported in other Enterobacteriaceae Here, we report the isolation and identification of a Shigella flexneri strain harboring mcr-1 from stool samples in a pig farm in China from 2009...
  47. McGuire E, Tiberi S, Ciesielczuk H, Melzer M. Shigellosis and toxic megacolon secondary to Shigella flexneri serotype 3a: The challenges of laboratory diagnosis. Int J Infect Dis. 2018;70:104-106 pubmed publisher
    We present a rare case of Shigella flexneri bacteraemia and toxic megacolon, and discuss the challenges of conventional laboratory techniques versus molecular PCR platforms in differentiating between Shigella species and Escherichia coli.
  48. Ambrosi C, Pompili M, Scribano D, Limongi D, Petrucca A, Cannavacciuolo S, et al. The Shigella flexneri OspB effector: an early immunomodulator. Int J Med Microbiol. 2015;305:75-84 pubmed publisher
    Through the action of the type three secretion system (T3SS) Shigella flexneri delivers several effectors into host cells to promote cellular invasion, multiplication and to exploit host-cell signaling pathways to modulate the host ..
  49. Chimnoi N, Reuk Ngam N, Chuysinuan P, Khlaychan P, Khunnawutmanotham N, Chokchaichamnankit D, et al. Characterization of essential oil from Ocimum gratissimum leaves: Antibacterial and mode of action against selected gastroenteritis pathogens. Microb Pathog. 2018;118:290-300 pubmed publisher
    ..against four gastroenteritis pathogens (Staphylococcus aureus, Escherichia coli, Salmonella Typhimurium, and Shigella flexneri). OGEO exhibited antibacterial effect, with MICs of 1-2 mg ml-1, against the tested species...
  50. Boal F, Puhar A, Xuereb J, Kunduzova O, Sansonetti P, Payrastre B, et al. PI5P Triggers ICAM-1 Degradation in Shigella Infected Cells, Thus Dampening Immune Cell Recruitment. Cell Rep. 2016;14:750-759 pubmed publisher
    b>Shigella flexneri, the pathogen responsible for bacillary dysentery, has evolved multiple strategies to control the inflammatory response...
  51. El Moslamy S. Bioprocessing strategies for cost-effective large-scale biogenic synthesis of nano-MgO from endophytic Streptomyces coelicolor strain E72 as an anti-multidrug-resistant pathogens agent. Sci Rep. 2018;8:3820 pubmed publisher
    ..applied in vitro against multi-drug resistant human pathogens and the large inhibition zone recorded against Shigella flexneri (108 ± 10.53 mm)...
  52. Willis A, Torraca V, Gomes M, Shelley J, Mazon Moya M, Filloux A, et al. Shigella-Induced Emergency Granulopoiesis Protects Zebrafish Larvae from Secondary Infection. MBio. 2018;9: pubmed publisher
    ..i>Shigella flexneri is a Gram-negative enteroinvasive pathogen controlled by neutrophils...
  53. Dragoi A, Agaisse H. The class II phosphatidylinositol 3-phosphate kinase PIK3C2A promotes Shigella flexneri dissemination through formation of vacuole-like protrusions. Infect Immun. 2015;83:1695-704 pubmed publisher
    Intracellular pathogens such as Shigella flexneri and Listeria monocytogenes achieve dissemination in the intestinal epithelium by displaying actin-based motility in the cytosol of infected cells...
  54. Mahmoud R, Stones D, Li W, Emara M, el Domany R, Wang D, et al. The Multivalent Adhesion Molecule SSO1327 plays a key role in Shigella sonnei pathogenesis. Mol Microbiol. 2016;99:658-73 pubmed publisher
    ..contrast to the up-regulation of IcsA-dependent and independent attachment and invasion by deoxycholate in Shigella flexneri, deoxycholate negatively regulates IcsA and MAM in S...
  55. Neiman Zenevich J, Stuart S, Abdel Nour M, Girardin S, Mogridge J. Listeria monocytogenes and Shigella flexneri Activate the NLRP1B Inflammasome. Infect Immun. 2017;85: pubmed publisher
    ..therefore sense microbial infection, as intracellular pathogens such as Listeria monocytogenes and Shigella flexneri cause metabolic stress as a result of nutrient scavenging and host cell damage...
  56. Campbell Valois F, Pontier S. Implications of Spatiotemporal Regulation of Shigella flexneri Type Three Secretion Activity on Effector Functions: Think Globally, Act Locally. Front Cell Infect Microbiol. 2016;6:28 pubmed publisher
    ..The activity of the T3SA of Shigella flexneri was recently demonstrated to display an on/off regulation during the infection...
  57. Vander Broek C, Zainal Abidin N, Stevens J. BipC, a Predicted Burkholderia pseudomallei Type 3 Secretion System Translocator Protein with Actin Binding Activity. Front Cell Infect Microbiol. 2017;7:333 pubmed publisher
    ..and Shigella flexneri respectively...
  58. Dragoi A, Agaisse H. The serine/threonine kinase STK11 promotes Shigella flexneri dissemination through establishment of cell-cell contacts competent for tyrosine kinase signaling. Infect Immun. 2014;82:4447-57 pubmed publisher
    b>Shigella flexneri is an intracellular pathogen that disseminates in the intestinal epithelium by displaying actin-based motility. We found that although S...
  59. Agaisse H. Molecular and Cellular Mechanisms of Shigella flexneri Dissemination. Front Cell Infect Microbiol. 2016;6:29 pubmed publisher
    The intracellular pathogen Shigella flexneri is the causative agent of bacillary dysentery in humans...
  60. Edgeworth J, Spencer J, Phalipon A, Griffin G, Sansonetti P. Cytotoxicity and interleukin-1beta processing following Shigella flexneri infection of human monocyte-derived dendritic cells. Eur J Immunol. 2002;32:1464-71 pubmed
    b>Shigella flexneri infection of macrophages (MPhi) leads to activation of caspase-1 by the IpaB virulence factor, which induces rapid cell death and release of mature IL-1beta. Here we show that S...
  61. Davoodabadi A, Soltan Dallal M, Rahimi Foroushani A, Douraghi M, Sharifi Yazdi M, Amin Harati F. Antibacterial activity of Lactobacillus spp. isolated from the feces of healthy infants against enteropathogenic bacteria. Anaerobe. 2015;34:53-8 pubmed publisher
    ..showed good probiotic potential and inhibited the growth of enteropathogenic bacteria including ETEC H10407, Shigella flexneri ATCC 12022, Shigella sonnei ATCC 9290, Salmonella enteritidis H7 and Yersinia enterocolitica ATCC 23715...
  62. Maggiore L, Yu L, Omasits U, Rossi O, Dougan G, Thomson N, et al. Quantitative proteomic analysis of Shigella flexneri and Shigella sonnei Generalized Modules for Membrane Antigens (GMMA) reveals highly pure preparations. Int J Med Microbiol. 2016;306:99-108 pubmed publisher
    ..The composition of the GMMA from hyperblebbing mutants of Shigella flexneri 2a and Shigella sonnei were quantitatively analyzed using high-sensitivity mass spectrometry with the label-..
  63. Riddle M, Kaminski R, Di Paolo C, Porter C, Gutierrez R, Clarkson K, et al. Safety and Immunogenicity of a Candidate Bioconjugate Vaccine against Shigella flexneri 2a Administered to Healthy Adults: a Single-Blind, Randomized Phase I Study. Clin Vaccine Immunol. 2016;23:908-917 pubmed
    ..Bioconjugation technology, exploited here for an Shigella flexneri 2a candidate vaccine, offers a novel and potentially cost-effective way to develop and produce vaccines ..
  64. Chen J, Tang J, Hu K, Zhao Y, Tang C. The production characteristics of volatile organic compounds and their relation to growth status of Staphylococcus aureus in milk environment. J Dairy Sci. 2018;101:4983-4991 pubmed publisher
    ..aureus mixed with Streptococcus agalactiae, Escherichia coli O157:H7, and Shigella flexneri, whereas correlations for 3-methyl-butanal were not statistically significant...
  65. Fasshuber H, Demers J, Chevelkov V, Giller K, Becker S, Lange A. Specific 13C labeling of leucine, valine and isoleucine methyl groups for unambiguous detection of long-range restraints in protein solid-state NMR studies. J Magn Reson. 2015;252:10-9 pubmed publisher
    ..This approach is demonstrated on the type-three secretion system needle of Shigella flexneri, where 49 methyl-methyl and methyl-nitrogen distance restraints including 10 unambiguous long-range distance ..
  66. Baker K, Parkhill J, Thomson N. Draft Genome Sequence of 24570, the Type Strain of Shigella flexneri. Genome Announc. 2015;3: pubmed publisher
    b>Shigella flexneri is a diarrheal pathogen that causes a large disease burden worldwide. We sequenced the genome of the publicly available type strain (S...
  67. Joubouhi C, Tamokou J, Ngnokam D, Voutquenne Nazabadioko L, Kuiate J. Iridoids from Canthium subcordatum iso-butanol fraction with potent biological activities. BMC Complement Altern Med. 2017;17:17 pubmed publisher
    ..concentrations (MBCs) of extracts and iridoids against Staphylococcus aureus, Vibrio cholerae and Shigella flexneri. Antioxidant activity was evaluated using 1,1-diphenyl-2-picrylhydrazyl (DPPH) and gallic acid equivalent ..
  68. Weddle E, Agaisse H. Spatial, Temporal, and Functional Assessment of LC3-Dependent Autophagy in Shigella flexneri Dissemination. Infect Immun. 2018;86: pubmed publisher
    i>Shigella flexneri disseminates within the colonic mucosa by displaying actin-based motility in the cytosol of epithelial cells...
  69. Nahm M, Yu J, Weerts H, Wenzel H, Tamilselvi C, Chandrasekaran L, et al. Development, Interlaboratory Evaluations, and Application of a Simple, High-Throughput Shigella Serum Bactericidal Assay. mSphere. 2018;3: pubmed publisher
    ..The serum bactericidal assay, along with a reference serum, should greatly facilitate Shigella vaccine development. ..
  70. Berger M, Berger P, Denamur E, Mellmann A, Dobrindt U. Core elements of the vegetative replication control of the Inc1 plasmid pO104_90 of Escherichia coli O104:H4 also regulate its transfer frequency. Int J Med Microbiol. 2018;308:962-968 pubmed publisher
    ..Enterobactericeae including clinically relevant enterobacterial pathogens like Salmonella typhimurium and Shigella flexneri. However, we found that this plasmid did not transfer into E...
  71. Baker K, Mather A, McGregor H, Coupland P, Langridge G, Day M, et al. The extant World War 1 dysentery bacillus NCTC1: a genomic analysis. Lancet. 2014;384:1691-7 pubmed publisher
    ..We aimed to generate a high-quality reference genome of the historical Shigella flexneri isolate NCTC1 and to examine the isolate for resistance to antimicrobials...
  72. Mazon Moya M, Colucci Guyon E, Mostowy S. Use of Shigella flexneri to study autophagy-cytoskeleton interactions. J Vis Exp. 2014;:e51601 pubmed publisher
    b>Shigella flexneri is an intracellular pathogen that can escape from phagosomes to reach the cytosol, and polymerize the host actin cytoskeleton to promote its motility and dissemination...
  73. Gomarasca M, F C Martins T, Greune L, Hardwidge P, Schmidt M, Rüter C. Bacterium-Derived Cell-Penetrating Peptides Deliver Gentamicin To Kill Intracellular Pathogens. Antimicrob Agents Chemother. 2017;61: pubmed publisher
    ..bacteria, including Escherichia coli K1, Salmonella enterica serovar Typhimurium, and Shigella flexneri Taken together, CPPs show great potential as delivery vehicles for antimicrobial agents and may ..
  74. Pons M, Torrents de la Peña A, Mensa L, Martón P, Ruiz Roldán L, Martínez Puchol S, et al. Differences in tetracycline resistance determinant carriage among Shigella flexneri and Shigella sonnei are not related to different plasmid Inc-type carriage. J Glob Antimicrob Resist. 2018;13:131-134 pubmed publisher
    ..causing traveller's diarrhoea. Tetracycline susceptibility was established in 187 Shigella spp. (74 Shigella flexneri and 113 Shigella sonnei), of which 153 isolates were recovered as a confirmed cause of traveller's diarrhoea...
  75. Necchi F, Saul A, Rondini S. Setup of luminescence-based serum bactericidal assay against Salmonella Paratyphi A. J Immunol Methods. 2018;461:117-121 pubmed publisher
    ..SBA method, against different pathogens, including Salmonella Typhimurium and Enteritidis, Shigella flexneri serovars 2a and 3a, Shigella sonnei and Neisseria meningitidis...
  76. Lee S, Picking W, Tzipori S. The immune response of two microbial antigens delivered intradermally, sublingually, or the combination thereof. Microbes Infect. 2014;16:796-803 pubmed publisher
    ..IpaB/IpaD antigens of Shigella flexneri type III secretion system, were admixed with dmLT as adjuvant and administered by each route alone or in ..
  77. Sun Q, Knirel Y, Wang J, Luo X, Senchenkova S, Lan R, et al. Serotype-converting bacteriophage SfII encodes an acyltransferase protein that mediates 6-O-acetylation of GlcNAc in Shigella flexneri O-antigens, conferring on the host a novel O-antigen epitope. J Bacteriol. 2014;196:3656-66 pubmed publisher
    b>Shigella flexneri O-antigen is an important and highly variable cell component presented on the outer leaflet of the outer membrane...
  78. Harouz H, Rachez C, Meijer B, Marteyn B, Donnadieu F, Cammas F, et al. Shigella flexneri targets the HP1γ subcode through the phosphothreonine lyase OspF. EMBO J. 2014;33:2606-22 pubmed publisher
    ..In a guinea pig model for Shigella enterocolitis, we observed that the defective type III secretion mxiD Shigella flexneri strain caused more HP1γ phosphorylation in the colon than the wild-type strain...
  79. Kayagaki N, Stowe I, Lee B, O Rourke K, Anderson K, Warming S, et al. Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling. Nature. 2015;526:666-71 pubmed publisher
    ..lipopolysaccharide from Gram-negative bacteria including Escherichia coli, Salmonella typhimurium, Shigella flexneri, and Burkholderia thailandensis activates mouse caspase-11, causing pyroptotic cell death, interleukin-1β ..
  80. Morado D, Hu B, Liu J. Using Tomoauto: A Protocol for High-throughput Automated Cryo-electron Tomography. J Vis Exp. 2016;:e53608 pubmed publisher
    ..This protocol has been effectively utilized to visualize the intact type III secretion system (T3SS) in Shigella flexneri minicells. It can be applicable to any project suitable for cryo-ET.
  81. Freed N, Bumann D, Silander O. Combining Shigella Tn-seq data with gold-standard E. coli gene deletion data suggests rare transitions between essential and non-essential gene functionality. BMC Microbiol. 2016;16:203 pubmed publisher
    ..results of a Tn-seq experiment designed to detect essential protein coding genes in the bacterial pathogen Shigella flexneri 2a 2457T on a genome-wide scale...
  82. Chattaway M, Schaefer U, Tewolde R, Dallman T, Jenkins C. Identification of Escherichia coli and Shigella Species from Whole-Genome Sequences. J Clin Microbiol. 2017;55:616-623 pubmed publisher
    ..Of the 25 mismatches identified, 10 were enteroinvasive E. coli isolates that were misidentified as Shigella flexneri or S. boydii by the kmer ID, and 8 were S. flexneri isolates misidentified by TB&S as S...
  83. Daligault H, Davenport K, Minogue T, Bishop Lilly K, Broomall S, Bruce D, et al. Genome Assembly of Shigella flexneri ATCC 12022, a Quality Control Reference Strain. Genome Announc. 2014;2: pubmed publisher
    b>Shigella flexneri causes shigellosis, severe and potentially life-threatening diarrhea, and accounts for 18% of shigellosis cases in the United States. Here, we present the 4.51-Mbp genome assembly of S...
  84. Bhullar K, Zarepour M, Yu H, Yang H, Croxen M, Stahl M, et al. The Serine Protease Autotransporter Pic Modulates Citrobacter rodentium Pathogenesis and Its Innate Recognition by the Host. Infect Immun. 2015;83:2636-50 pubmed
    ..of serine protease autotransporters of Enterobacteriaceae (SPATEs) produced by enteric pathogens such as Shigella flexneri and enteroaggregative Escherichia coli...
  85. Gawthorne J, Audry L, McQuitty C, Dean P, Christie J, Enninga J, et al. Visualizing the Translocation and Localization of Bacterial Type III Effector Proteins by Using a Genetically Encoded Reporter System. Appl Environ Microbiol. 2016;82:2700-2708 pubmed publisher
    ..Further evidence for the versatility of the reporter was demonstrated by fusing LOV to the C terminus of the Shigella flexneri effector IpaB. IpaB-LOV localized preferentially at bacterial poles before translocation...
  86. Ranjbar R, Behnood V, Memariani H, Najafi A, Moghbeli M, Mammina C. Molecular characterisation of quinolone-resistant Shigella strains isolated in Tehran, Iran. J Glob Antimicrob Resist. 2016;5:26-30 pubmed publisher
    ..was Shigella sonnei (54; 74.0%). Of the 23 quinolone-resistant isolates, 4 (17.4%) (including 2 Shigella flexneri, 1 S. sonnei and 1 Shigella boydii) contained the qnrS gene...
  87. Patel M, Akhani R, Patel A, Dedania S, Patel D. A single and two step isomerization process for d-tagatose and l-ribose bioproduction using l-arabinose isomerase and d-lyxose isomerase. Enzyme Microb Technol. 2017;97:27-33 pubmed publisher
    ..The l-arabinose isomerase gene from Shigella flexneri (Sf-AI) was cloned and expressed in Escherichia coli BL-21...
  88. Allen G, Harris K. In Vitro Resistance Selection in Shigella flexneri by Azithromycin, Ceftriaxone, Ciprofloxacin, Levofloxacin, and Moxifloxacin. Antimicrob Agents Chemother. 2017;61: pubmed publisher
    i>Shigella flexneri continues to be a major cause of diarrhea-associated illness, and increasing resistance to first-line antimicrobials complicates the treatment of infections caused by this pathogen...
  89. Vubil D, Ballesté Delpierre C, Mabunda R, Acácio S, Garrine M, Nhampossa T, et al. Antibiotic resistance and molecular characterization of shigella isolates recovered from children aged less than 5 years in Manhiça, Southern Mozambique. Int J Antimicrob Agents. 2018;51:881-887 pubmed publisher
    ..Serotyping was performed using specific antisera. The clonal relationship of Shigella flexneri and Shigella sonnei was assessed by pulsed-field gel electrophoresis (PFGE)...
  90. Pavankumar A, Zelenin S, Lundin A, Schulte T, Rajarathinam K, Rebellato P, et al. Bioanalytical advantages of a novel recombinant apyrase enzyme in ATP-based bioluminescence methods. Anal Chim Acta. 2018;1025:118-123 pubmed publisher
    ..In light of this, we have developed a recombinant Shigella flexneri apyrase (RSFA) enzyme and analysed its ATP depletion potential with five commercial biochemical sources ..
  91. Zaidi M, Estrada García T. Shigella: A Highly Virulent and Elusive Pathogen. Curr Trop Med Rep. 2014;1:81-87 pubmed
    ..i>Shigella dysenteriae and Shigella flexneri infections are predominant in resource-limited settings...
  92. Hargreaves J, Le Guen Y, Guerreiro C, Descroix K, Mulard L. Linear synthesis of the branched pentasaccharide repeats of O-antigens from Shigella flexneri 1a and 1b demonstrating the major steric hindrance associated with type-specific glucosylation. Org Biomol Chem. 2014;12:7728-49 pubmed publisher
    b>Shigella flexneri serotypes 1b and 1a are Gram-negative enteroinvasive bacteria causing shigellosis in humans. The O-antigen from S...