Moraxella catarrhalis

Summary

Alias: "Mikrokkokus catarrhalis" (sic) Frosch and Kolle in Flugge 1896, Branhamella catarrhalis, Mikrokkokus catarrhalis, Moraxella (subgen. Branhamella Catlin 1970) catarrhalis (Frosch and Kolle 1896) Bovre 1984, Moraxella catarrhalis (Frosch and Kolle1896) Henriksen and Bovre 1968, Branhamella catarrhalis (Frosch and Kolle 1896) Catlin 1970 (Approved Lists 1980), Moraxella catarralis

Top Publications

  1. Xiao Y, Wei Z, Shen P, Ji J, Sun Z, Yu H, et al. Bacterial-resistance among outpatients of county hospitals in China: significant geographic distinctions and minor differences between central cities. Microbes Infect. 2015;17:417-25 pubmed publisher
    ..6%), ceftriaxone (13.0%), and erythromycin (96.4%). β-lactamase was produced by 96.5% of Moraxella catarrhalis strains, and 36.2% of H. influenzae isolates were resistant to ampicillin. Azithromycin-resistant H...
  2. Suzuki K, Kurono Y, Ikeda K, Watanabe A, Iwamoto A, Totsuka K, et al. Nationwide surveillance of 6 otorhinolaryngological infectious diseases and antimicrobial susceptibility pattern in the isolated pathogens in Japan. J Infect Chemother. 2015;21:483-91 pubmed publisher
    ..Streptococcus pyogenes, and Staphylococcus aureus), three gram-negative bacteria (Haemophilus influenzae, Moraxella Catarrhalis, and Pseudomonas aeruginosa), and three anaerobic bacteria (Peptostreptococcus spp., Prevotella spp...
  3. Dube F, Kaba M, Robberts F, Ah Tow L, Lubbe S, Zar H, et al. Respiratory microbes present in the nasopharynx of children hospitalised with suspected pulmonary tuberculosis in Cape Town, South Africa. BMC Infect Dis. 2016;16:597 pubmed
    ..b>Moraxella catarrhalis (64 %), Streptococcus pneumoniae (42 %), Haemophilus influenzae spp (29 %) and Staphylococcus aureus (..
  4. Orban Gyapai O, Liktor Busa E, Kúsz N, Stefkó D, Urban E, Hohmann J, et al. Antibacterial screening of Rumex species native to the Carpathian Basin and bioactivity-guided isolation of compounds from Rumex aquaticus. Fitoterapia. 2017;118:101-106 pubmed publisher
    ..thyrsiflorus) were investigated against Staphylococcus epidermidis, S. aureus, MRSA, Bacillus subtilis, Moraxella catarrhalis, Streptococcus pyogenes, S. pneumoniae, S...
  5. Carvalhaes C, Huband M, Reinhart H, Flamm R, Sader H. Antimicrobial Activity of Omadacycline Tested against Clinical Bacterial Isolates from Hospitals in Mainland China, Hong Kong, and Taiwan: Results from the SENTRY Antimicrobial Surveillance Program (2013 to 2016). Antimicrob Agents Chemother. 2019;63: pubmed publisher
    ..5/1 mg/liter) regardless of β-lactamase production and was active against Moraxella catarrhalis (MIC50/90, ≤0.12/0.25 mg/liter)...
  6. Brook I. Microbiology of chronic rhinosinusitis. Eur J Clin Microbiol Infect Dis. 2016;35:1059-68 pubmed publisher
    ..with community-acquired acute bacterial sinusitis are Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, and Streptococcus pyogenes...
  7. Gadsby N, McHugh M, Russell C, Mark H, Conway Morris A, Laurenson I, et al. Development of two real-time multiplex PCR assays for the detection and quantification of eight key bacterial pathogens in lower respiratory tract infections. Clin Microbiol Infect. 2015;21:788.e1-788.e13 pubmed publisher
    ..and accurate quantification of Streptococcus pneumoniae, Haemophilus influenzae, Staphylococcus aureus, Moraxella catarrhalis, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumannii...
  8. Pfaller M, Flamm R, Mendes R, Streit J, Smart J, Hamed K, et al. Ceftobiprole Activity against Gram-Positive and -Negative Pathogens Collected from the United States in 2006 and 2016. Antimicrob Agents Chemother. 2019;63: pubmed publisher
    ..6% susceptible). A total of 99.6% of all Haemophilus influenzae and Moraxella catarrhalis isolates were inhibited at ≤1 mg/liter ceftobiprole, and 72...
  9. Pfaller M, Huband M, Rhomberg P, Flamm R. Surveillance of Omadacycline Activity against Clinical Isolates from a Global Collection (North America, Europe, Latin America, Asia-Western Pacific), 2010-2011. Antimicrob Agents Chemother. 2017;61: pubmed publisher
    ..influenzae (MIC50/90, 1/1 μg/ml) regardless of β-lactamase status and against Moraxella catarrhalis (MIC50/90, 0.12/0.25 μg/ml)...

More Information

Publications160 found, 100 shown here

  1. Yanagihara K, Kadota J, Aoki N, Matsumoto T, Yoshida M, Yagisawa M, et al. Nationwide surveillance of bacterial respiratory pathogens conducted by the surveillance committee of Japanese Society of Chemotherapy, the Japanese Association for Infectious Diseases, and the Japanese Society for Clinical Microbiology in 2010: Gene. J Infect Chemother. 2015;21:410-20 pubmed publisher
    ..aureus, 189 Streptococcus pneumoniae, 4 Streptococcus pyogenes, 182 Haemophilus influenzae, 74 Moraxella catarrhalis, 139 Klebsiella pneumoniae and 160 Pseudomonas aeruginosa). Ratio of methicillin-resistant S...
  2. Demirci F, Karaca N, Tekin M, Demirci B. Anti-inflammatory and antibacterial evaluation of Thymus sipyleus Boiss. subsp. sipyleus var. sipyleus essential oil against rhinosinusitis pathogens. Microb Pathog. 2018;122:117-121 pubmed publisher
    ..epidermidis, Streptococcus pyogenes, S. pneumoniae, Pseudomonas aeruginosa, Haemophilus influenzae and Moraxella catarrhalis. Additionally, the in vitro anti-inflammatory activity was evaluated by 5-lipoxygenase (5-LOX) inhibitory ..
  3. Dicks L, Knoetze H, Van Reenen C. Otitis Media: A Review, with a Focus on Alternative Treatments. Probiotics Antimicrob Proteins. 2009;1:45-59 pubmed publisher
    ..The microbiology of OM differs, with Streptococcus pneumoniae, non-typeable Haemophilus influenzae and Moraxella catarrhalis the most commonly isolated pathogens. The emergence of penicillin-resistant Strep...
  4. Tazón Varela M, Alonso Valle H, Muñoz Cacho P, Gallo Teran J, Piris García X, Pérez Mier L. [Increasing incidence of community-acquired pneumonia caused by atypical microorganisms]. Semergen. 2017;43:437-444 pubmed publisher
    ..5/59, 9%), methicillin-resistant Staphylococcus aureus (3/59, 5%), Pseudomonas aeruginosa (2/59, 3%), Moraxella catarrhalis (2/59, 3%), Legionella pneumophila (2/59, 3%), and Haemophilus influenza (2/59, 3%)...
  5. Jiang L, Ren H, Zhou H, Qin T, Chen Y. Simultaneous Detection of Nine Key Bacterial Respiratory Pathogens Using Luminex xTAG® Technology. Int J Environ Res Public Health. 2017;14: pubmed publisher
    ..These were Streptococcus pneumoniae, Moraxella catarrhalis, Staphylococcus aureus, Streptococcus pyogenes, Haemophilus influenzae, ..
  6. Coleman A, Wood A, Bialasiewicz S, Ware R, Marsh R, Cervin A. The unsolved problem of otitis media in indigenous populations: a systematic review of upper respiratory and middle ear microbiology in indigenous children with otitis media. Microbiome. 2018;6:199 pubmed publisher
    ..colonization with the three main otopathogens (Haemophilus influenzae, Streptococcus pneumoniae, and Moraxella catarrhalis) in indigenous children with OM...
  7. Kawasaki S, Aoki N, Kikuchi H, Nakayama H, Saito N, Shimada H, et al. Clinical and microbiological evaluation of hemodialysis-associated pneumonia (HDAP): should HDAP be included in healthcare-associated pneumonia?. J Infect Chemother. 2011;17:640-5 pubmed publisher
    ..1%), Klebsiella pneumoniae (8.7%), Haemophilus influenzae (7.2%), and Moraxella catarrhalis (5.8%)...
  8. Xu L, Zeng J, Jiang C, Wang H, Li Y, Wen W, et al. Isolation and determination of four potential antimicrobial components from Pseudomonas aeruginosa extracts. Int J Med Sci. 2017;14:1368-1374 pubmed publisher
    ..i> (CS, Gram-positive bacilli), Acinetobacter baumannii (AB, Gram-negative bacilli), Moraxella catarrhalis (MC, Gram-negative diplococcus), Candida albicans (CA, fungi), Candida tropicalis (CT, ..
  9. Van Hoecke H, De Paepe A, Lambert E, Van Belleghem J, Cools P, Van Simaey L, et al. Haemophilus influenzae biofilm formation in chronic otitis media with effusion. Eur Arch Otorhinolaryngol. 2016;273:3553-3560 pubmed
    ..7 % were culture positive for bacteria and 47.0 % were culture positive for Haemophilus influenzae, Moraxella catarrhalis, Staphylococcus aureus and/or Streptococcus pneumoniae...
  10. Yanagihara K, Watanabe A, Aoki N, Matsumoto T, Yoshida M, Sato J, et al. Nationwide surveillance of bacterial respiratory pathogens conducted by the surveillance committee of Japanese Society of Chemotherapy, the Japanese Association for Infectious Diseases, and the Japanese Society for Clinical Microbiology in 2012: Gene. J Infect Chemother. 2017;23:587-597 pubmed publisher
    ..aureus, 225 Streptococcus pneumoniae, 16 Streptococcus pyogenes, 231 Haemophilus influenzae, 147 Moraxella catarrhalis, 167 Klebsiella pneumoniae and 218 Pseudomonas aeruginosa). Ratio of methicillin-resistant S...
  11. Hu Y, Keniry M, Palmer S, Bullard J. Discovery and Analysis of Natural-Product Compounds Inhibiting Protein Synthesis in Pseudomonas aeruginosa. Antimicrob Agents Chemother. 2016;60:4820-9 pubmed publisher
    ..panel of pathogenic organisms, including Enterococcus faecalis, Escherichia coli, Haemophilus influenzae, Moraxella catarrhalis, P...
  12. Jouneau S, Brinchault G, Desrues B. [Management of COPD exacerbations: from primary care to hospitalization]. Presse Med. 2014;43:1359-67 pubmed publisher
    ..and respiratory syncytial virus) or bacterial (Haemophilus influenzae, Streptococcus pneumoniae, or Moraxella catarrhalis). Pollutant exposure can also lead to AE COPD, such as NO2, SO2, ozone or particulates (PM10 and PM2.5)...
  13. Jeannoel M, Lina G, Rasigade J, Lina B, Morfin F, Casalegno J. Microorganisms associated with respiratory syncytial virus pneumonia in the adult population. Eur J Clin Microbiol Infect Dis. 2019;38:157-160 pubmed publisher
    ..with Streptococcus pneumonia, Haemophilus influenza, Staphylococcus aureus, Pseudomonas aeruginosa, and Moraxella catarrhalis. Most patients were elderly (55.6%) and patients with comorbidities (77.8%)...
  14. Verhagen L, De Groot R. Recurrent, protracted and persistent lower respiratory tract infection: A neglected clinical entity. J Infect. 2015;71 Suppl 1:S106-11 pubmed publisher
    ..bacterial infection (mainly non-typeable Haemophilus influenzae, Streptococcus pneumoniae and Moraxella catarrhalis) and neutrophilic airway inflammation...
  15. Jacobs F. [Lower respiratory tract infections in immunocompetent adult]. Rev Med Brux. 2017;38:313-319 pubmed
    ..and pneumonia are mainly due to a trio of bacteria (Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis)...
  16. Taylor S, Leong L, Mobegi F, Choo J, Wesselingh S, Yang I, et al. Long-Term Azithromycin Reduces Haemophilus influenzae and Increases Antibiotic Resistance in Severe Asthma. Am J Respir Crit Care Med. 2019;: pubmed publisher
    ..significantly affect levels of Streptococcus pneumoniae, Staphylococcus aureus, Pseudomonas aeruginosa or Moraxella catarrhalis. Of the 89 antibiotic resistance genes detected, macrolide resistance genes (erm(B), erm(F), msr(E), mef(A)..
  17. Huband M, Pfaller M, Shortridge D, Flamm R. Surveillance of omadacycline activity tested against clinical isolates from the United States and Europe: Results from the SENTRY Antimicrobial Surveillance Programme, 2017. J Glob Antimicrob Resist. 2019;: pubmed publisher
    ..8%S [CABP breakpoints]) including all β-lactamase positive isolates and inhibited 100.0% of Moraxella catarrhalis isolates at ≤0.25 mg/L...
  18. Boulund F, Karlsson R, Gonzales Siles L, Johnning A, Karami N, Al Bayati O, et al. Typing and Characterization of Bacteria Using Bottom-up Tandem Mass Spectrometry Proteomics. Mol Cell Proteomics. 2017;16:1052-1063 pubmed publisher
    ..coli, Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus pneumoniae, Moraxella catarrhalis, and Haemophilus influenzae), using both simulated data generated by in silico peptide ..
  19. Georgopapadakou N. The wobbly status of ketolides: where do we stand?. Expert Opin Investig Drugs. 2014;23:1313-9 pubmed publisher
    ..responsible for community-acquired pneumonia (CAP): Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis as well as atypical pathogens (Mycoplasma pneumoniae, Chlamydia pneumoniae, Legionella pneumophila)...
  20. Karaca N, Demirci B, Demirci F. Evaluation of Lavandula stoechas L. subsp. stoechas L., Mentha spicata L. subsp. spicata L. essential oils and their main components against sinusitis pathogens. Z Naturforsch C. 2018;: pubmed publisher
    ..pathogens Streptococcus pneumoniae, Streptococcus pyogenes, Staphylococcus aureus, Haemophilus influenzae, Moraxella catarrhalis, and Pseudomonas aeruginosa using in vitro agar diffusion, microdilution, and vapor diffusion methods...
  21. Fukutani K, Nascimento Carvalho C, Van der Gucht W, Wollants E, Khouri R, Dierckx T, et al. Pathogen transcriptional profile in nasopharyngeal aspirates of children with acute respiratory tract infection. J Clin Virol. 2015;69:190-6 pubmed publisher
    ..Bacterial transcripts from Staphylococcus aureus, Haemophilus influenzae, Streptococcus pneumoniae, Moraxella catarrhalis, Mycoplasma pneumoniae and Chlamydophila pneumoniae were detected in 77, 69, 26, 8, 3 and 2% of samples, ..
  22. de Bruin O, Chiefari A, Wroblewski D, Egan C, Kelly Cirino C. A novel chemical lysis method for maximum release of DNA from difficult-to-lyse bacteria. Microb Pathog. 2019;126:292-297 pubmed publisher
    ..Francisella philomiragia, Yersinia enterocolitica, Bacillus thuringiensis, Pseudomonas aeruginosa, Moraxella catarrhalis and Klebsiella pneumoniae...
  23. Sader H, Flamm R, Streit J, Carvalhaes C, Mendes R. Antimicrobial activity of ceftaroline and comparator agents tested against organisms isolated from patients with community-acquired bacterial pneumonia in Europe, Asia, and Latin America. Int J Infect Dis. 2018;77:82-86 pubmed publisher
    ..9% in the APAC region to 15.0% in E-EUR. Ceftaroline also demonstrated potent activity against Moraxella catarrhalis (n=613; MIC50/90, 0.06/0.25mg/l) and Haemophilus parainfluenzae (n=23; MIC50/90, 0...
  24. Collignon P, Turnidge J. Fusidic acid in vitro activity. Int J Antimicrob Agents. 1999;12 Suppl 2:S45-58 pubmed
    ..Bordetella pertussis and Moraxella catarrhalis. It has no activity against other aerobic Gram-negative species...
  25. Flamm R, Rhomberg P, Sader H. In Vitro Activity of the Novel Lactone Ketolide Nafithromycin (WCK 4873) against Contemporary Clinical Bacteria from a Global Surveillance Program. Antimicrob Agents Chemother. 2017;61: pubmed publisher
    ..comparable in vitro activities against 1,002 Haemophilus influenzae isolates and 504 Moraxella catarrhalis isolates...
  26. Wang M, Lu X, Hu A, Zhang M, Li X, Deng S, et al. Etiological characteristics of chlamydia trachoma conjunctivitis of Primary Boarding School students in the Qinghai Tibetan area. Sci China Life Sci. 2016;59:555-60 pubmed publisher
    ..cases, and infections with multiple bacteria, particularly Haemophilus influenzae, Staphylococcus aureus, Moraxella catarrhalis, and Streptococcus pneumoniae, accounted for the remaining 57.14% (12/21). Of the 14 C...
  27. Santerre Henriksen A, Smart J, Hamed K. Susceptibility to ceftobiprole of respiratory-tract pathogens collected in the United Kingdom and Ireland during 2014-2015. Infect Drug Resist. 2018;11:1309-1320 pubmed publisher
    ..6% (236/237) for Moraxella catarrhalis. All Staphylococcus aureus isolates, including methicillin-susceptible S...
  28. Goto H, Shimada K, Ikemoto H, Oguri T. Antimicrobial susceptibility of pathogens isolated from more than 10,000 patients with infectious respiratory diseases: a 25-year longitudinal study. J Infect Chemother. 2009;15:347-60 pubmed publisher
    ..aeruginosa infection. Regarding Moraxella catarrhalis, beta-lactamase-producing strains already constituted a majority of the isolates in 1990, and the ..
  29. Laulajainen Hongisto A, Saat R, Lempinen L, Aarnisalo A, Jero J. Children hospitalized due to acute otitis media: how does this condition differ from acute mastoiditis?. Int J Pediatr Otorhinolaryngol. 2015;79:1429-35 pubmed publisher
    ..aeruginosa. In children under 2 years-of-age, the most common pathogens were S. pneumoniae (43%), Moraxella catarrhalis (14%), and S. aureus (7%). S. pyogenes and P. aeruginosa were only found in children over 2 years-of-age...
  30. Parrott G, Nebeya D, Kinjo T, Miyagi K, Haranaga S, Higa F, et al. Etiological analysis and epidemiological comparison among adult CAP and NHCAP patients in Okinawa, Japan. J Infect Chemother. 2017;23:452-458 pubmed publisher
    ..majority of patients suffered from Streptococcus pneumoniae (32/200), Haemophilus influenzae (22/200), and Moraxella catarrhalis (16/200)...
  31. Canut A, Isla A, Rodríguez Gascón A. Pharmacokinetic/pharmacodynamic analysis to evaluate ceftaroline fosamil dosing regimens for the treatment of community-acquired bacterial pneumonia and complicated skin and skin-structure infections in patients with normal and impaired renal functio. Int J Antimicrob Agents. 2015;45:399-405 pubmed publisher
    ..meticillin-susceptible Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis (CFR>90%). However, against meticillin-resistant S. aureus (MRSA), the CFR was 72%...
  32. Belfield K, Bayston R, Birchall J, Daniel M. Do orally administered antibiotics reach concentrations in the middle ear sufficient to eradicate planktonic and biofilm bacteria? A review. Int J Pediatr Otorhinolaryngol. 2015;79:296-300 pubmed publisher
    ..The highest antibiotic levels against Staphylococcus aureus reach 8.3×MIC, against Moraxella catarrhalis 33.2×MIC, against Haemophilus influenzae 31.2×MIC, and against Streptococcus pneumoniae 46...
  33. Soyletir G, Altinkanat G, Gur D, Altun B, Tunger A, Aydemir S, et al. Results from the Survey of Antibiotic Resistance (SOAR) 2011-13 in Turkey. J Antimicrob Chemother. 2016;71 Suppl 1:i71-83 pubmed publisher
    ..0% BLNAR adjusted)]. Streptococcus pyogenes (n?=?222) and Moraxella catarrhalis (n?=?40) isolates remained highly susceptible to amoxicillin/clavulanic acid, cephalosporins and ..
  34. Ordemann A, Stanford J, Sullivan D, Reed J. Can contaminated water be rendered safe for nasal saline irrigations?. Laryngoscope. 2017;127:1513-1519 pubmed publisher
    ..Sterile water was contaminated with known concentrations of Staphylococcus aureus, Pseudomonas aeruginosa, Moraxella catarrhalis, Acinetobacter baumannii, Klebsiella pneumonia, Legionella pneumophila, and Naegleria fowleri...
  35. Simusika P, Bateman A, Theo A, Kwenda G, Mfula C, Chentulo E, et al. Identification of viral and bacterial pathogens from hospitalized children with severe acute respiratory illness in Lusaka, Zambia, 2011-2012: a cross-sectional study. BMC Infect Dis. 2015;15:52 pubmed publisher
    ..7%) were the most commonly detected viruses, while Streptococcus pneumonie (109/199; 54.8%) and Moraxella catarrhalis (92/199; 46.2%) were the most commonly detected bacteria...
  36. Smith K, Voogt R, Ruiz T, Mintz K. The conserved carboxyl domain of MorC, an inner membrane protein of Aggregatibacter actinomycetemcomitans, is essential for membrane function. Mol Oral Microbiol. 2016;31:43-58 pubmed publisher
    ..of the Gammaproteobacteria: Haemophilus influenzae, Escherichia coli, Pseudomonas aeruginosa, and Moraxella catarrhalis. The A...
  37. Jiang L, Ren H, Zhou H, Zhao S, Hou B, Yan J, et al. Simultaneous Detection of 13 Key Bacterial Respiratory Pathogens by Combination of Multiplex PCR and Capillary Electrophoresis. Biomed Environ Sci. 2017;30:549-561 pubmed publisher
    ..for lower respiratory tract infections, including Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli, Staphylococcus aureus, Mycoplasma ..
  38. Edin A, Granholm S, Koskiniemi S, Allard A, Sjöstedt A, Johansson A. Development and laboratory evaluation of a real-time PCR assay for detecting viruses and bacteria of relevance for community-acquired pneumonia. J Mol Diagn. 2015;17:315-24 pubmed publisher
    ..positive agreement with standard tests for Streptococcus pneumoniae and 100% for Mycoplasma pneumoniae, Moraxella catarrhalis, and Staphylococcus aureus. Negative percentage of agreement was >95% for M...
  39. Vasconcellos Â, Clarencio J, Andrade D, Cardoso M, Barral A, Nascimento Carvalho C. Systemic cytokines and chemokines on admission of children hospitalized with community-acquired pneumonia. Cytokine. 2018;107:1-8 pubmed publisher
    ..2 (IQR: 12.4-54.1). The other 128 cases had other causative agents detected (Haemophilus influenzae, Moraxella catarrhalis, atypical bacteria and viruses) with the median IL-6 concentration being 9.0 (IQR: 4.1-22.0; p < 0...
  40. Karppinen S, Vuononvirta J, He Q, Waris M, Peltola V. Effects of Rhinovirus Infection on Nasopharyngeal Bacterial Colonization in Infants With Wild or Variant Types of Mannose-Binding Lectin and Toll-Like Receptors 3 and 4. J Pediatric Infect Dis Soc. 2013;2:240-7 pubmed publisher
    ..Of 337 infants, 61 were positive for rhinovirus and 187 were colonized by Streptococcus pneumoniae, Moraxella catarrhalis, Haemophilus influenzae, or Staphylococcus aureus...
  41. Tamir S, Roth Y, Dalal I, Goldfarb A, Grotto I, Marom T. Changing trends of acute otitis media bacteriology in central Israel in the pneumococcal conjugate vaccines era. Pediatr Infect Dis J. 2015;34:195-9 pubmed publisher
    ..MEF cultures which tested positive for otopathogens, Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis and multiple bacteria grew in 60 (57%), 39 (37%), 2 (2%) and 5 (5%) episodes, respectively. S...
  42. Niki Y, Hanaki H, Matsumoto T, Yagisawa M, Kohno S, Aoki N, et al. Nationwide surveillance of bacterial respiratory pathogens conducted by the Japanese Society of Chemotherapy in 2008: general view of the pathogens' antibacterial susceptibility. J Infect Chemother. 2011;17:510-23 pubmed publisher
    ..aureus, 211 Streptococcus pneumoniae, 6 Streptococcus pyogenes, 187 Haemophilus influenzae, 106 Moraxella catarrhalis, 126 Klebsiella pneumoniae, and 162 Pseudomonas aeruginosa)...
  43. Joslin S, Pybus C, Labandeira Rey M, Evans A, Attia A, Brautigam C, et al. A Moraxella catarrhalis two-component signal transduction system necessary for growth in liquid media affects production of two lysozyme inhibitors. Infect Immun. 2015;83:146-60 pubmed publisher
    There are a paucity of data concerning gene products that could contribute to the ability of Moraxella catarrhalis to colonize the human nasopharynx...
  44. Kaur R, Czup K, Casey J, Pichichero M. Correlation of nasopharyngeal cultures prior to and at onset of acute otitis media with middle ear fluid cultures. BMC Infect Dis. 2014;14:640 pubmed publisher
    ..7%) NP cultures compared to 253 (12.2%) for Nontypeable Haemophilus influenzae (NTHi) and 723 (34.9%) for Moraxella catarrhalis (Mcat). At onset of AOM 256 (48...
  45. Ahmad A, Viljoen A. The in vitro antimicrobial activity of Cymbopogon essential oil (lemon grass) and its interaction with silver ions. Phytomedicine. 2015;22:657-65 pubmed publisher
    ..Gram-positive (Staphylococcus aureus and Enterococcus faecalis), two Gram-negative (Escherichia coli and Moraxella catarrhalis) and two yeast species (Candida albicans and Candida tropicalis)...
  46. Wang S, Ji W, Zhang X, Gu W, Yan Y, Zhou W, et al. [Bacterial pathogenic characteristics of respiratory tract infection in children in Suzhou, China: an analysis of 14,994 cases]. Zhongguo Dang Dai Er Ke Za Zhi. 2016;18:44-50 pubmed
    ..79%), followed by Haemophilus influenzae (5.02%) and Moraxella catarrhalis (2.91%)...
  47. Yatsyshina S, Mayanskiy N, Shipulina O, Kulichenko T, Alyabieva N, Katosova L, et al. Detection of respiratory pathogens in pediatric acute otitis media by PCR and comparison of findings in the middle ear and nasopharynx. Diagn Microbiol Infect Dis. 2016;85:125-30 pubmed publisher
    ..4%; Haemophilus influenzae, 17.9%; Staphylococcus aureus, 16.8%; Streptococcus pyogenes, 12.3%; Moraxella catarrhalis, 9.5%; rhinovirus, 9.5%; and adenovirus, 3.4%...
  48. Kyd J, McGrath J, Krishnamurthy A. Mechanisms of bacterial resistance to antibiotics in infections of COPD patients. Curr Drug Targets. 2011;12:521-30 pubmed
    ..isolated bacteria in the lower respiratory tract of COPD patients are nontypeable Haemophilus influenzae, Moraxella catarrhalis and Streptococcus pneumoniae, with growing evidence of the significance of Pseudomonas aeruginosa ..
  49. Carral N, Lukas J, Oteo I, Suarez E. Impact of poor compliance with levofloxacin and moxifloxacin on respiratory tract infection antimicrobial efficacy: a pharmacokinetic/pharmacodynamic simulation study. Int J Antimicrob Agents. 2015;45:79-83 pubmed publisher
    ..8 for Streptococcus pneumoniae and >100 for Haemophilus influenzae and Moraxella catarrhalis (PTA>90%)...
  50. Stolić I, Čipčić Paljetak H, Perić M, Matijašić M, Stepanić V, Verbanac D, et al. Synthesis and structure-activity relationship of amidine derivatives of 3,4-ethylenedioxythiophene as novel antibacterial agents. Eur J Med Chem. 2015;90:68-81 pubmed publisher
    ..against laboratory strains of Staphyloccocus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, Moraxella catarrhalis, respectively and 4-32 μg/ml against clinical isolates of sensitive and resistant S...
  51. Han X, Lv W, Guo S, Cushman M, Liang J. Synthesis and structure-activity relationships of novel 9-oxime acylides with improved bactericidal activity. Bioorg Med Chem. 2015;23:6437-53 pubmed publisher
    ..susceptible and mef-encoded Streptococcus pneumoniae, inducible-erm resistant Streptococcus pyogenes, and Moraxella catarrhalis. A docking model indicated that the carbamoylpyridyl group of 3h may hydrogen bond to G2061 in addition to ..
  52. López Fabal M, Gómez Garcés J, López Hontangas J, Sanz N, Muñoz C, Regodón M. Vitek MS matrix-assisted laser desorption ionization-time of flight mass spectrometry for identifying respiratory bacterial pathogens: a fast and efficient method. Rev Esp Quimioter. 2015;28:242-6 pubmed
    ..specimens routinely identified as Streptococcus pneumoniae (43), Haemophilus influenzae (64) and Moraxella catarrhalis (44)...
  53. Maračić S, Kraljević T, Paljetak H, Perić M, Matijašić M, Verbanac D, et al. 1,2,3-Triazole pharmacophore-based benzofused nitrogen/sulfur heterocycles with potential anti-Moraxella catarrhalis activity. Bioorg Med Chem. 2015;23:7448-63 pubmed publisher
    ..29 that demonstrated extremely narrow spectrum activity towards fastidious Gram-negative bacteria Moraxella catarrhalis. Selected hybrid showed the potency against Moraxella catarrhalis (MIC⩽0...
  54. Ruíz Carrillo J, Vázquez Guerrero E, Mercado Uribe M. [Orbital cellulitis complicated by subperiosteal abscess due to Streptococcus pyogenes infection]. Bol Med Hosp Infant Mex. 2017;74:134-140 pubmed publisher
    ..related to this disease are Haemophilus influenzae B, Staphylococcus aureus, Streptococcus pneumoniae and Moraxella catarrhalis, which correspond to 95% of cases...
  55. Smith Vaughan H, Binks M, Beissbarth J, Chang A, McCallum G, Mackay I, et al. Bacteria and viruses in the nasopharynx immediately prior to onset of acute lower respiratory infections in Indigenous Australian children. Eur J Clin Microbiol Infect Dis. 2018;37:1785-1794 pubmed publisher
    ..Streptococcus pneumoniae (74%), Haemophilus influenzae (75%) and Moraxella catarrhalis (88%) were commonly identified across all swabs...
  56. Edouard S, Million M, Bachar D, Dubourg G, Michelle C, Ninove L, et al. The nasopharyngeal microbiota in patients with viral respiratory tract infections is enriched in bacterial pathogens. Eur J Clin Microbiol Infect Dis. 2018;37:1725-1733 pubmed publisher
    ..in these patients, including Staphylococcus aureus, Haemophilus influenzae, Streptococcus pneumoniae, Moraxella catarrhalis, Dol osigranulum pigrum and Corynebacterium propinquum/pseudodiphtheriticum, whose role in respiratory ..
  57. Ács K, Balázs V, Kocsis B, Bencsik T, Böszörményi A, Horváth G. Antibacterial activity evaluation of selected essential oils in liquid and vapor phase on respiratory tract pathogens. BMC Complement Altern Med. 2018;18:227 pubmed publisher
    ..mutans, S. pyogenes, Haemophilus influenzae, H. parainfluenzae, and Moraxella catarrhalis. Furthermore, we wanted to compare the antibacterial effect of these EOs in two different test systems to ..
  58. Fukuyama H, Yamashiro S, Kinjo K, Tamaki H, Kishaba T. Validation of sputum Gram stain for treatment of community-acquired pneumonia and healthcare-associated pneumonia: a prospective observational study. BMC Infect Dis. 2014;14:534 pubmed publisher
    ..5% and 91.5% for Streptococcus pneumoniae, 60.9% and 95.1% for Haemophilus influenzae, 68.2% and 96.1% for Moraxella catarrhalis, 39.5% and 98.2% for Klebsiella pneumoniae, 22.2% and 99.8% for Pseudomonas aeruginosa, 9...
  59. Beck T, Lloyd D, Kuskovsky R, Minah J, Arora K, Plotkin B, et al. Non-transpeptidase binding arylthioether β-lactams active against Mycobacterium tuberculosis and Moraxella catarrhalis. Bioorg Med Chem. 2015;23:632-47 pubmed publisher
    ..These thioethers exhibit inhibitory and cidal activity against serine β-lactamase producing Mycobacterium tuberculosis wild type strain (Mtb) and multiple (n=8) β-lactamase producing Moraxella catarrhalis clinical isolates.
  60. Gutbier B, Fischer K, Doehn J, von Lachner C, Herr C, Klaile E, et al. Moraxella catarrhalis induces an immune response in the murine lung that is independent of human CEACAM5 expression and long-term smoke exposure. Am J Physiol Lung Cell Mol Physiol. 2015;309:L250-61 pubmed publisher
    In patients with chronic obstructive pulmonary disease (COPD), Moraxella catarrhalis infection of the lower airways is associated with chronic colonization and inflammation during stable disease and acute exacerbations...
  61. Ngo C, Massa H, Thornton R, Cripps A. Predominant Bacteria Detected from the Middle Ear Fluid of Children Experiencing Otitis Media: A Systematic Review. PLoS ONE. 2016;11:e0150949 pubmed publisher
    ..pneumoniae and H. influenzae 3.2 fold compared to culture, whilst Moraxella catarrhalis was 4.5 times more frequently identified by PCR...
  62. Boelsen L, Dunne E, Lamb K, Bright K, Cheung Y, Tikoduadua L, et al. Long-term impact of pneumococcal polysaccharide vaccination on nasopharyngeal carriage in children previously vaccinated with various pneumococcal conjugate vaccine regimes. Vaccine. 2015;33:5708-5714 pubmed publisher
    ..rates and densities of Streptococcus pneumoniae, Haemophilus influenzae, Staphylococcus aureus and Moraxella catarrhalis. Nasopharyngeal swabs (n=194) were obtained from healthy children who participated in FiPP (now aged 5-7 ..
  63. Ariff A, Wise M, Kahler C, Tay C, Peters F, Perkins T, et al. Novel Moraxella catarrhalis prophages display hyperconserved non-structural genes despite their genomic diversity. BMC Genomics. 2015;16:860 pubmed publisher
    b>Moraxella catarrhalis is an important pathogen that often causes otitis media in children, a disease that is not currently vaccine preventable...
  64. Heinrich A, Haarmann H, Zahradnik S, Frenzel K, Schreiber F, Klassert T, et al. Moraxella catarrhalis decreases antiviral innate immune responses by down-regulation of TLR3 via inhibition of p53 in human bronchial epithelial cells. FASEB J. 2016;30:2426-34 pubmed publisher
    ..Coinfections of bacterial and viral pathogens are associated with more severe exacerbations. Moraxella catarrhalis is one of the most frequent lower respiratory tract pathogens detected in COPD...
  65. Evangelista P, Evangelista G, Ogrich L. Infection after Total Knee Arthroplasty by M. Catarrhalis Associated with Rheumatoid Arthritis and DMARDs Therapy. Bull Hosp Jt Dis (2013). 2017;75:140-142 pubmed
    b>Moraxella catarrhalis is not commonly associated with prosthetic joint infection (PJI)...
  66. Sheikh S, Fasih N, Irfan S, Zafar A. β-Lactamase production and antimicrobial susceptibility pattern of Moraxella catarrhalis isolates: report from Pakistan. Asian Pac J Trop Med. 2014;7S1:S228-31 pubmed publisher
    To assess the frequency of β-lactamase production and antimicrobial resistance in Moraxella catarrhalis isolated from clinical specimens in Pakistan...
  67. Biedenbach D, Bouchillon S, Hackel M, Miller L, Scangarella Oman N, Jakielaszek C, et al. In Vitro Activity of Gepotidacin, a Novel Triazaacenaphthylene Bacterial Topoisomerase Inhibitor, against a Broad Spectrum of Bacterial Pathogens. Antimicrob Agents Chemother. 2016;60:1918-23 pubmed publisher
    ..25; Escherichia coli, 2; Moraxella catarrhalis, ≤ 0.06; Streptococcus pneumoniae (0.25), Haemophilus influenzae, 1; Clostridium perfringens, 0...
  68. Frank M, Collins P, Peak I, Grice I, Wilson J. An Unusual Carbohydrate Conformation is Evident in Moraxella catarrhalis Oligosaccharides. Molecules. 2015;20:14234-53 pubmed publisher
    ..For lgt2Δ the presence of more than one conformation is supported by the NOE data. ..
  69. Haarmann H, Steiner T, Schreiber F, Heinrich A, Zweigner J, N Guessan P, et al. The role and regulation of Moraxella catarrhalis-induced human beta-defensin 3 expression in human pulmonary epithelial cells. Biochem Biophys Res Commun. 2015;467:46-52 pubmed publisher
    Bacterial colonisation with Moraxella catarrhalis may partly sustain chronic inflammation in the lower airways of patients with chronic obstructive pulmonary disease (COPD)...
  70. Hassoun A, Huff M, Weisman D, Chahal K, Asis E, Stalons D, et al. Seasonal variation of respiratory pathogen colonization in asymptomatic health care professionals: A single-center, cross-sectional, 2-season observational study. Am J Infect Control. 2015;43:865-70 pubmed publisher
    ..Methicillin-resistant Staphylococcus aureus (MRSA), Moraxella catarrhalis, and coronavirus were the most frequently detected potentially infectious agents...
  71. Alanin M, Nielsen K, von Buchwald C, Skov M, Aanaes K, Høiby N, et al. A longitudinal study of lung bacterial pathogens in patients with primary ciliary dyskinesia. Clin Microbiol Infect. 2015;21:1093.e1-7 pubmed publisher
    ..Other common pathogens were P. aeruginosa, Streptococcus pneumoniae, Moraxella catarrhalis and Staphylococcus aureus. The number of patients colonized with P...
  72. Chan C, Richter K, Wormald P, Psaltis A, Vreugde S. Alloiococcus otitidis Forms Multispecies Biofilm with Haemophilus influenzae: Effects on Antibiotic Susceptibility and Growth in Adverse Conditions. Front Cell Infect Microbiol. 2017;7:344 pubmed publisher
    ..and commonly accepted otopathogens, such as Haemophilus influenzae, Streptococcus pneumonia, and Moraxella catarrhalis, have been demonstrated to form polymicrobial biofilms within the middle ear cleft...
  73. Ren D, Almudevar A, Murphy T, Lafontaine E, Campagnari A, Luke Marshall N, et al. Serum antibody response to Moraxella catarrhalis proteins OMP CD, OppA, Msp22, Hag, and PilA2 after nasopharyngeal colonization and acute otitis media in children. Vaccine. 2015;33:5809-14 pubmed publisher
    There is no licensed vaccine for Moraxella catarrhalis (Mcat), which is a prominent bacterium causing acute otitis media (AOM) in children and lower respiratory tract infections in adults...
  74. Kumagai S, Ishida T, Tachibana H, Ito Y, Ito A, Hashimoto T. Impact of bacterial coinfection on clinical outcomes in pneumococcal pneumonia. Eur J Clin Microbiol Infect Dis. 2015;34:1839-47 pubmed publisher
    ..3 %), methicillin-susceptible Staphylococcus aureus (MSSA) (15 patients, 20.0 %), and Moraxella catarrhalis (13 patients, 17.3 %)...
  75. Funaki T, Inoue E, Miyairi I. Clinical characteristics of the patients with bacteremia due to Moraxella catarrhalis in children: a case-control study. BMC Infect Dis. 2016;16:73 pubmed publisher
    Invasive diseases due to Moraxella catarrhalis are rare in children, even in immunocompromised hosts. Therefore, data regarding clinical characteristics and risk factors of such patients are limited...
  76. Bønnelykke K, Vissing N, Sevelsted A, Johnston S, Bisgaard H. Association between respiratory infections in early life and later asthma is independent of virus type. J Allergy Clin Immunol. 2015;136:81-86.e4 pubmed publisher
    ..and bocavirus) and 3 pathogenic airway bacteria (Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis) were identified in airway secretions sampled during episodes of troublesome lung symptoms in the first 3 ..
  77. Pavlović D, Mutak S. Synthesis and antibacterial evaluation of novel 4″-glycyl linked quinolyl-azithromycins with potent activity against macrolide-resistant pathogens. Bioorg Med Chem. 2016;24:1255-67 pubmed publisher
    ..In addition, potential lead compounds 9e and 22f demonstrated outstanding levels of activity against Moraxella catarrhalis and inducibly MLSB resistant Staphylococcus aureus...
  78. Cindrić M, Peric M, Kralj M, Martin Kleiner I, David Cordonnier M, Paljetak H, et al. Antibacterial and antiproliferative activity of novel 2-benzimidazolyl- and 2-benzothiazolyl-substituted benzo[b]thieno-2-carboxamides. Mol Divers. 2018;22:637-646 pubmed publisher
    ..Staphylococcus aureus and Enterococcus faecalis) and Gram-negative bacteria (Escherichia coli and Moraxella catarrhalis)...
  79. Liu G, Gradstedt H, Ermert D, Englund E, Singh B, Su Y, et al. Moraxella catarrhalis Evades Host Innate Immunity via Targeting Cartilage Oligomeric Matrix Protein. J Immunol. 2016;196:1249-58 pubmed publisher
    b>Moraxella catarrhalis is a respiratory tract pathogen commonly causing otitis media in children and acute exacerbations in patients suffering from chronic obstructive pulmonary disease...
  80. Wang H, Gu X, Weng Y, Xu T, Fu Z, Peng W, et al. Quantitative analysis of pathogens in the lower respiratory tract of patients with chronic obstructive pulmonary disease. BMC Pulm Med. 2015;15:94 pubmed publisher
    ..Klebsiella pneumoniae, Streptococcus pneumoniae, Pseudomonos aeruginosa, Haemophilus influenzeae, and Moraxella catarrhalis were detected by RT-qPCR...
  81. Barman T, Kumar M, Mathur T, Namba E, Singh D, Chaira T, et al. In Vitro and In Vivo Activities of DS-2969b, a Novel GyrB Inhibitor, and Its Water-Soluble Prodrug, DS11960558, against Methicillin-Resistant Staphylococcus aureus. Antimicrob Agents Chemother. 2018;62: pubmed publisher
    ..antibacterial activity against Gram-positive aerobes but not against Gram-negative aerobes, except for Moraxella catarrhalis and Haemophilus influenzae DS-2969b was active against MRSA with an MIC90 of 0...
  82. Biedenbach D, Iaconis J, Sahm D. Comparative in vitro activities of ceftaroline and ceftriaxone against bacterial pathogens associated with respiratory tract infections: results from the AWARE surveillance study. J Antimicrob Chemother. 2016;71:3459-3464 pubmed
    ..In all, 13?005 isolates of Staphylococcus aureus, Streptococcus pneumoniae, Moraxella catarrhalis and Haemophilus influenzae were collected in 2012-14 from 39 countries in the Asia-Pacific region, Europe, ..
  83. Gaeta N, Lima S, Teixeira A, Ganda E, Oikonomou G, Gregory L, et al. Deciphering upper respiratory tract microbiota complexity in healthy calves and calves that develop respiratory disease using shotgun metagenomics. J Dairy Sci. 2017;100:1445-1458 pubmed publisher
    ..Pasteurella multocida was among the 20 most abundant species, and Moraxella catarrhalis, commonly associated with pneumonia in humans, was detected in all groups...
  84. Wang H, Drake S, Yong C, Gucek M, Lyes M, Rosenberg A, et al. A Genoproteomic Approach to Detect Peptide Markers of Bacterial Respiratory Pathogens. Clin Chem. 2017;63:1398-1408 pubmed publisher
    ..digestion were performed on 14-25 whole genomes representing strains of Acinetobacter baumannii, Moraxella catarrhalis, Pseudomonas aeruginosa, Stenotrophomonas maltophilia, and Klebsiella pneumoniae...
  85. Hu F, Zhu D, Wang F, Morrissey I, Wang J, Torumkuney D. Results from the Survey of Antibiotic Resistance (SOAR) 2009-11 and 2013-14 in China. J Antimicrob Chemother. 2016;71 Suppl 1:i33-43 pubmed publisher
    ..During 2009-11, 434 Streptococcus pneumoniae, 307 Haemophilus influenzae and 140 Moraxella catarrhalis were collected from eight centres and during 2013-14, 208 S. pneumoniae, 185 H. influenzae and 80 M...
  86. Volgers C, Grauls G, Hellebrand P, Savelkoul P, Stassen F. Budesonide, fluticasone propionate, and azithromycin do not modulate the membrane vesicle release by THP-1 macrophages and respiratory pathogens during macrophage infection. Inflammopharmacology. 2017;25:643-651 pubmed publisher
    ..The macrolide antibiotic azithromycin only inhibited the growth of Moraxella catarrhalis but no effects were observed on bacterial MV release at a concentration that is achieved locally in the ..
  87. Escribano Montaner A, Garcia de Lomas J, Villa Asensi J, Asensio de la Cruz O, de la Serna Blázquez O, Santiago Burruchaga M, et al. Bacteria from bronchoalveolar lavage fluid from children with suspected chronic lower respiratory tract infection: results from a multi-center, cross-sectional study in Spain. Eur J Pediatr. 2018;177:181-192 pubmed publisher
    ..Streptococcus pneumoniae, Haemophilus influenzae, or Moraxella catarrhalis were identified from BALF with a bacterial load indicative of infection (>?104?colony-..
  88. Raclavsky V, Bardon J, PetruŽelová J, Procházková P, Novotny R, Navrátilová L, et al. [Prolonged culture in a humid chamber increases the yields of pathogenic bacteria from the respiratory tract samples of patients suffering from cystic fibrosis]. Klin Mikrobiol Infekc Lek. 2016;22:40-2 pubmed
    ..69 versus 49), whereas there was little or no benefit at all for Staphylococcus aureus (87 versus 73) and Moraxella catarrhalis (10 versus 10)...
  89. Ren D, Almudevar A, Murphy T, Lafontaine E, Campagnari A, Luke Marshall N, et al. Serum antibody response to Moraxella catarrhalis proteins in stringently defined otitis prone children. Vaccine. 2017;: pubmed publisher
    b>Moraxella catarrhalis (Mcat) is a frequent pathogen of acute otitis media (AOM) in young children...
  90. Sillanpää S, Sipilä M, Hyoty H, Rautiainen M, Laranne J. Antibiotic resistance in pathogens causing acute otitis media in Finnish children. Int J Pediatr Otorhinolaryngol. 2016;85:91-4 pubmed publisher
    ..common pathogen was Haemophilus influenzae 17 (40%), followed by Streptococcus pneumoniae in 15 (35%) and Moraxella catarrhalis in 8 (19%). Other pathogens were detected in 3 (7%) of cases...
  91. Chonmaitree T, Trujillo R, Jennings K, Alvarez Fernandez P, Patel J, Loeffelholz M, et al. Acute Otitis Media and Other Complications of Viral Respiratory Infection. Pediatrics. 2016;137: pubmed publisher
    ..05). Significant bacterial-viral interactions occurred with Moraxella catarrhalis and a variety of respiratory viruses and altered URI and AOM risks...
  92. Pfaller M, Flamm R, Duncan L, Streit J, Castanheira M, Sader H. Antimicrobial activity of ceftobiprole and comparator agents when tested against contemporary Gram-positive and -negative organisms collected from Europe (2015). Diagn Microbiol Infect Dis. 2018;91:77-84 pubmed publisher
    ..Ceftobiprole inhibited 70.4% of P. aeruginosa at ?4 mg/L and all isolates of Haemophilus influenzae and Moraxella catarrhalis at ? 0.5 mg/L...