Research Topics
Genomes and GenesSpecies
| Escherichia coliSummaryAlias: Escherichia coli retron Ec86, Escherichia coli retron Ec79, Escherichia coli retron Ec67, Escherichia coli retron Ec107, Escherichia coli (Migula 1895) Castellani and Chalmers 1919, "Bacillus coli" Migula 1895, "Bacterium coli" (Migula 1895) Lehmann and Neumann 1896, Bacterium coli commune, Bacterium coli, Bacillus coli, "Bacterium coli commune" Escherich 1885, Eschericia coli, Escherchia coli, Enterococcus coli, bacterium 10a, bacterium E3 Top Publications
Research Grants
| Scientific Experts
|
Detail Information
Publications
Isolation and characterization of a gene involved in hemagglutination by an avian pathogenic Escherichia coli strainD L Provence
Department of Biology, Washington University, St Louis, Missouri 63130
Infect Immun 62:1369-80. 1994..the isolation and characterization of a gene that may be important in the adherence of avian pathogenic Escherichia coli to the avian respiratory tract. The E...
The newly characterized colicin Y provides evidence of positive selection in pore-former colicin diversificationM A Riley
Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT 06511, USA
Microbiology 146:1671-7. 2000..have been proposed in the process of protein diversification of the large family of antimicrobial toxins of Escherichia coli, known as the colicins...
Genetic structure and distribution of four pathogenicity islands (PAI I(536) to PAI IV(536)) of uropathogenic Escherichia coli strain 536Ulrich Dobrindt
Institut für Molekulare Infektionsbiologie, Universitat Wurzburg, D 97070 Wurzburg, Germany
Infect Immun 70:6365-72. 2002For the uropathogenic Escherichia coli strain 536 (O6:K15:H31), the DNA sequences of three pathogenicity islands (PAIs) (PAI I(536) to PAI III(536)) and their flanking regions (about 270 kb) were determined to further characterize the ..
Analysis of the EHEC hly operon and its location in the physical map of the large plasmid of enterohaemorrhagic Escherichia coli O157:h7H Schmidt
Institut für Hygiene und Mikrobiologie, Universitat Wurzburg, Germany
Microbiology 142:907-14. 1996Almost all clinical enterohaemorrhagic Escherichia coli (EHEC) O157:H7 isolates harbour a large virulence plasmid designated pO157. In this study, pO157 of EHEC O157:H7 reference strain EDL 933 was characterized at the molecular level...
Exoproducts of the Escherichia coli strain H22 inhibiting some enteric pathogens both in vitro and in vivoL Cursino
Department of General Biology, ICB Universidade Federal de Minas Gerais, Belo Horizonte MG, Brazil
J Appl Microbiol 100:821-9. 2006The antagonistic activity of the Escherichia coli strain H22 against enteric bacteria was studied both in vitro and in vivo.
Prevalence of ColE1-like plasmids and colicin K production among uropathogenic Escherichia coli strains and quantification of inhibitory activity of colicin KMatija Rijavec
Department of Biology, Biotechnical Faculty, University of Ljubljana, Vecna pot 111, Ljubljana, Slovenia
Appl Environ Microbiol 73:1029-32. 2007Colicin K exhibited pronounced inhibitory activity against uropathogenic Escherichia coli (UPEC) strains...
Risk factors for and outcomes of bloodstream infection caused by extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella species in childrenTheoklis E Zaoutis
Division of Infectious Diseases, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
Pediatrics 115:942-9. 2005The increasing prevalence of infections caused by extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella species (ESBL-EK) has become a growing concern in the hospitalized patient population...
99mTc-labeled antimicrobial peptide ubiquicidin (29-41) accumulates less in Escherichia coli infection than in Staphlococcus aureus infectionMuhammad Saeed Akhtar
Punjab Institute of Nuclear Medicine, Faisalabad, Pakistan
J Nucl Med 45:849-56. 200499mTc-Labeled antimicrobial peptide ubiquicidin, (99m)Tc-UBI (29-41) in a freeze-dried kit, was evaluated as a bacterial infection-seeking agent in Staphlococcus aureus- and Escherichia coli-induced infections.
Rapid identification of protein biomarkers of Escherichia coli O157:H7 by matrix-assisted laser desorption ionization-time-of-flight-time-of-flight mass spectrometry and top-down proteomicsClifton K Fagerquist
Western Regional Research Center, Agricultural Research Service, U S Department of Agriculture, 800 Buchanan Street, Albany, California 94710, USA
Anal Chem 82:2717-25. 2010Six protein biomarkers from two strains of Escherichia coli O157:H7 and one non-O157:H7, nonpathogenic strain of E...
Expression in Escherichia coli of Y5-mutant and N-terminal domain-deleted DNA gyrase B proteins affects strongly plasmid maintenanceL Brino
Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS, INSERM, ULP, Illkirch, France
Plasmid 38:188-201. 1997b>Escherichia coli DNA gyrase B subunit (GyrB) is composed of a 43-kDa N-terminal domain containing an ATP-binding site and a 47-kDa C-terminal domain involved in the interaction with the gyrase A subunit (GyrA)...
Expression in Escherichia coli of Y5 mutant and N-terminal domain-deleted DNA gyrase B proteins affects strongly plasmid maintenanceL Brino
Institut de Genetique et de Biologie Moleculaire et Cellulaire, Illkirch, France
Plasmid 39:21-34. 1998b>Escherichia coli DNA gyrase B subunit (GyrB) is composed of a 43-kDa N-terminal domain containing an ATP-binding site and a 47-kDa C-terminal domain involved in the interaction with the gyrase A subunit (GyrA)...
Refined structure of Escherichia coli heat-labile enterotoxin, a close relative of cholera toxinT K Sixma
BIOSON Research Institute, University of Groningen, The Netherlands
J Mol Biol 230:890-918. 1993Heat-labile enterotoxin (LT) from Escherichia coli is a bacterial protein toxin with an AB5 multimer structure, in which the B pentamer has a membrane binding function and the A subunit is needed for enzymatic activity...
Genetic interactions between the Escherichia coli umuDC gene products and the beta processivity clamp of the replicative DNA polymeraseM D Sutton
Biology Department, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
J Bacteriol 183:2897-909. 2001The Escherichia coli umuDC gene products encode DNA polymerase V, which participates in both translesion DNA synthesis (TLS) and a DNA damage checkpoint control...
Linkage between fructose 1,6-bisphosphate binding and the dimer-tetramer equilibrium of Escherichia coli glycerol kinase: critical behavior arising from change of ligand stoichiometryPeng Yu
Department of Biochemistry and Biophysics, Center for Advanced Biomolecular Research, Texas A and M University, College Station, Texas 77843 2128, USA
Biochemistry 42:4243-52. 2003b>Escherichia coli glycerol kinase (EC 2.7.1...
The Escherichia coli BarA-UvrY two-component system is a virulence determinant in the urinary tractHenrik Tomenius
Swedish Institute for Infectious Disease Control, SE 17182 Solna, Sweden
BMC Microbiol 6:27. 2006..and the Pseudomonas spp GacS-GacA all belong to the same orthologous family of two-component systems as the Escherichia coli BarA-UvrY...
An activator of glutamate decarboxylase genes regulates the expression of enteropathogenic Escherichia coli virulence genes through control of the plasmid-encoded regulator, PerS Shin
Center for Vaccine Development and Department of Microbiology and Immunology, University of Maryland School of Medicine, 685 W Baltimore St, Baltimore, MD 21201, USA
Mol Microbiol 41:1133-50. 2001Enteropathogenic Escherichia coli (EPEC) is a major cause of infantile diarrhoea in a number of developing countries and is the prototype of pathogenic bacteria that cause attaching and effacing (A/E) intestinal lesions...
Effects of heat stress on the antimicrobial drug resistance of Escherichia coli of the intestinal flora of swineM H Moro
Department of Microbiology, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA
J Appl Microbiol 88:836-44. 2000The effects of heat stress on the antimicrobial drug resistance of Escherichia coli of the intestinal tract of swine were studied in animals from a farm that had not been supplementing antimicrobials in feed for the past 10 years...
New enterovirulent Escherichia coli serogroup 64474 showing antigenic and genotypic relationships to Shigella boydii 16Armando Navarro
Departamento de Salud Publica, Universidad Nacional Autonoma de Mexico, Ciudad Universitaria, Mexico City DF 04510, Mexico
J Med Microbiol 59:453-61. 2010Studies based on the analysis of housekeeping genes indicate that Escherichia coli and all Shigella species, except for Shigella boydii type 13, belong to a single species...
Valyl-tRNA synthetase from Escherichia coli MALDI-MS identification of the binding sites for L-valine or for noncognate amino acids upon qualitative comparative labeling with reactive amino-acid analogsC Hountondji
Laboratoire de Biochimie CNRS UMR 7654, Ecole Polytechnique, Palaiseau, France
Eur J Biochem 267:4789-98. 2000..These reagents were used for qualitative comparative labeling of Escherichia coli valyl-tRNA synthetase (ValRS), an enzyme with Val/Ile editing activity, in order to identify the binding ..
Modulation of serum cytokine levels by a novel superoxide dismutase mimetic, M40401, in an Escherichia coli model of septic shock: correlation with preserved circulating catecholaminesHeather Macarthur
Department of Pharmacological and Physiological Science, Saint Louis University School of Medicine, MO, USA
Crit Care Med 31:237-45. 2003..Here we examined if maintenance of serum catecholamine levels by the superoxide dismutase mimetic, M40401, modulates serum cytokine levels and arterial hypotension in an Escherichia coli-infected conscious rat model of septic shock.
Safety of raw meat and shellfish in Vietnam: an analysis of Escherichia coli isolations for antibiotic resistance and virulence genesThi Thu Hao Van
Biotechnology and Environmental Biology, School of Applied Sciences, RMIT University, Bundoora West Campus, Bundoora, Melbourne, VIC 3083, Australia
Int J Food Microbiol 124:217-23. 2008This study was conducted to examine a current baseline profile of antimicrobial resistance and virulence of Escherichia coli isolated from foods commonly sold in the market place in Vietnam. E...
Comparison between the growth of Yersinia enterocolitica, listeria monocytogenes, escherichia coli O157:H7 and salmonella spp. in ground beef packed by three commercially used packaging techniquesH Nissen
MATFORSK, Norwegian Food Research Institute, Oslovn
Int J Food Microbiol 59:211-20. 2000Growth of the pathogens Yersinia enterocolitica, Listeria monocytogenes, Escherichia coli O157:H7 and strains of Salmonella were compared in ground beef packed in modified atmospheres of 60% CO2/40% N2/0...
Prevalent phenotypes and antibiotic resistance in Escherichia coli and Klebsiella pneumoniae at an Indian tertiary care hospital: plasmid-mediated cefoxitin resistanceM Shahid
Department of Microbiology, Jawaharlal Nehru Medical College and Hospital, Aligarh Muslim University, Aligarh 202002, Uttar Pradesh, India
Int J Infect Dis 12:256-64. 2008..Due to increased transcontinental movement of the human population, it would be wise to know the prevalence and resistance complexity of these strains, well in advance, in order to formulate a policy for empirical therapy...
The catalytic, glycosyl transferase and acyl transferase modules of the cell wall peptidoglycan-polymerizing penicillin-binding protein 1b of Escherichia coliM Terrak
Centre d Ingénierie des Protéines, Universite de Liege, Institut de Chimie, B6, B 4000 Sart Tilman Liège, Belgium
Mol Microbiol 34:350-64. 1999The penicillin-binding protein (PBP) 1b of Escherichia coli catalyses the assembly of lipid-transported N-acetyl glucosaminyl-beta-1, 4-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-(L)-meso-diaminopimelyl+ ++- (L)-D-alanyl-D-alanine ..
Heterogeneity in enterohemorrhagic Escherichia coli O157:H7 fecal shedding in cattle is related to Escherichia coli O157:H7 colonization of the small and large intestineDanica Baines
Lethbridge Research Centre, Agriculture and Agri Food Canada, Lethbridge, ABT1J4B1, Canada
Can J Microbiol 54:984-95. 2008In the last decade, Escherichia coli O157:H7 have emerged as important pathogens of the gastrointestinal tract of humans. Healthy cattle have been identified as the primary reservoir, however, the factors affecting heterogeneous E...
Comparison of Escherichia coli and Klebsiella pneumoniae liver abscessesShiuan Chih Chen
Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan
Am J Med Sci 334:97-105. 2007b>Escherichia coli and Klebsiella pneumoniae are the most common causative pathogens of pyogenic liver abscesses...
Evaluation of antibacterial activity of selected Iranian essential oils against Staphylococcus aureus and Escherichia coli in nutrient broth mediumMohammad Mohsenzadeh
Department of Food Hygiene and Public Health, Ferdowsi University of Mashhad, P O Box 91775 1793, Mashhad, Iran
Pak J Biol Sci 10:3693-7. 2007..Artmesia dracunculus) and pennyroyal (Mentha pullegium) essential oils on the Staphylococcus aureus and Escherichia coli was studied in nutrient broth medium...
Evaluation of fermentation, drying, and/or high pressure processing on viability of Listeria monocytogenes, Escherichia coli O157:H7, Salmonella spp., and Trichinella spiralis in raw pork and Genoa salamiAnna C S Porto-Fett
U S Department of Agriculture, Agricultural Research Service, Eastern Regional Research Center, Microbial Food Safety Research Unit, 600 East Mermaid Lane, Wyndmoor, PA 19038, USA
Int J Food Microbiol 140:61-75. 2010..of fermentation, drying, and high pressure processing (HPP) to inactivate Listeria monocytogenes, Escherichia coli O157:H7, Salmonella spp., and Trichinella spiralis in Genoa salami produced with trichinae-infected pork...
Effects of mucin and its carbohydrate constituents on Escherichia coli O157 growth in batch culture fermentations with ruminal or fecal microbial inoculumJ T Fox
Department of Diagnostic Medicine and Pathobiology, Kansas State University, Manhattan 66506, USA
J Anim Sci 87:1304-13. 2009In cattle, Escherichia coli O157 generally persists in the large intestine more often than in the rumen. In contrast to the rumen, the large intestine is lined by an epithelial membrane that secretes mucus...
Comparative enzymatic properties of GapB-encoded erythrose-4-phosphate dehydrogenase of Escherichia coli and phosphorylating glyceraldehyde-3-phosphate dehydrogenaseS Boschi-Muller
Laboratoire d Enzymologie et de Génie Génétique, Universite de Nancy I, URA CNRS 457, B P 239, 54506 Vandoeuvre les Nancy Cedex, France
J Biol Chem 272:15106-12. 1997GapB-encoded protein of Escherichia coli and glyceraldehyde-3-phosphate dehydrogenase (GAPDH) share more than 40% amino acid identity...
Binding of Escherichia coli primary replicative helicase DnaB protein to single-stranded DNA. Long-range allosteric conformational changes within the protein hexamerM J Jezewska
Department of Human Biological Chemistry and Genetics, University of Texas Medical Branch at Galveston 77555 1053, USA
Biochemistry 35:2129-45. 1996Quantitative analyses of the interactions of the Escherichia coli primary replicative helicase DnaB protein with single-stranded DNA have been performed using the thermodynamically rigorous fluorescence titration technique...
Effective medicinal plants against enterohaemorrhagic Escherichia coli O157:H7Supayang Voravuthikunchai
School of Biotechnology and Biomolecular Sciences, The University of New South Wales, Sydney 2052, Australia
J Ethnopharmacol 94:49-54. 2004..of subinhibitory concentrations of antibiotics on the production of verocytotoxin (VT) by enterohaemorrhagic Escherichia coli (EHEC) O157:H7 has been claimed...
Alternative respiratory pathways of Escherichia coli: energetics and transcriptional regulation in response to electron acceptorsG Unden
Institut für Mikrobiologie und Weinforschung, Universitat Mainz, Germany
Biochim Biophys Acta 1320:217-34. 1997The electron-transport chains of Escherichia coli are composed of many different dehydrogenases and terminal reductases (or oxidases) which are linked by quinones (ubiquinone, menaquinone and demethylmenaquinone)...
Crystal structure of Escherichia coli thioredoxin reductase refined at 2 A resolution. Implications for a large conformational change during catalysisG Waksman
Laboratory of Molecular Biophysics, Rockefeller University, New York, NY 10021
J Mol Biol 236:800-16. 1994The crystal structures of three forms of Escherichia coli thioredoxin reductase have been refined: the oxidized form of the wild-type enzyme at 2...
[Selective screening of enterohemorrhagic Escherichia coli depending on hemolysis on Beutin's washed sheep blood agar plates]N Kimura
Ishikawa Health Service Association
Kansenshogaku Zasshi 72:223-30. 1998..et al have studied hemolysin production in a large number of serologically diverse verotoxin (VT) producing Escherichia coli (VTEC) strains and found a close association between hemolysin production and VT production...
Polyamine stress at high pH in Escherichia coli K-12Elizabeth Yohannes
Department of Biology, Kenyon College, Gambier, OH 43022, USA
BMC Microbiol 5:59. 2005Polyamines such as spermine and spermidine are required for growth of Escherichia coli; they interact with nucleic acids, and they bind to ribosomes...
A comparison of mutation spectra detected by the Escherichia coli lac(+) reversion assay and the Salmonella typhimurium his(+) reversion assayT Ohta
School of Life Science, Tokyo University of Pharmacy and Life Science, 1432 1 Horinouchi, Hachioji, Tokyo 192 0392, Japan
Mutagenesis 15:317-23. 2000Each of the Escherichia coli tester strains in the WP3101P-WP3106P series contains an F' plasmid with a different base substitution mutation within the lacZ gene...
Mode of selectivity in cyclic AMP receptor protein-dependent promoters in Escherichia coliE A Pyles
Department of Human Biological Chemistry and Genetics, University of Texas Medical Branch, Galveston 77556 1055, USA
Biochemistry 35:1162-72. 1996b>Escherichia coli cAMP receptor protein (CRP) controls more than 20 genes. There are significant differences in the promoter regions in these genes...
Kinetic mechanism of DNA binding and DNA-induced dimerization of the Escherichia coli Rep helicaseK P Bjornson
Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St Louis, Missouri 63110, USA
Biochemistry 35:2268-82. 1996The monomeric Escherichia coli Rep protein undergoes a DNA-induced dimerization upon binding either single-stranded (ss) or duplex DNA with the dimer being the active form of the Rep helicase...
Microbial source tracking by DNA sequence analysis of the Escherichia coli malate dehydrogenase geneKathryn M Ivanetich
University of California San Francisco, Biomolecular Resource Center and Department of Pharmaceutical Chemistry, Surge 104, 90 Medical Center Way, San Francisco, CA 94143 0541, USA
J Microbiol Methods 67:507-26. 2006..of microbial organisms by DNA sequencing proposed by Olive and Bean were applied to several genes in Escherichia coli to identify targets for the development of microbial source tracking assays...
Perineal swabs reveal effect of super shedders on the transmission of Escherichia coli O157:H7 in commercial feedlotsT P Stephens
Alberta Agriculture and Rural Development, Agriculture Centre, 100, 5401 1st Avenue South, Lethbridge, Alberta, Canada T1J 4V6
J Anim Sci 87:4151-60. 2009Cattle that shed more than 10(4) cfu/g of Escherichia coli O157 in feces have been described as super shedders (SS) and are thought to have major impacts on prevalence and transmission of this organism...
Probing the role of tightly bound phosphoenolpyruvate in Escherichia coli 3-deoxy-d-manno-octulosonate 8-phosphate synthase catalysis using quantitative time-resolved electrospray ionization mass spectrometry in the millisecond time rangeZhili Li
Department of Pharmacology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520, USA
Anal Biochem 343:35-47. 2005b>Escherichia coli 3-deoxy-D-manno-octulosonate 8-phosphate (KDO8P) synthase catalyzes the condensation of phosphoenolpyruvate (PEP) and D-arabinose 5-phosphate (A5P) to produce KDO8P and inorganic phosphate...
Hemolytic-Uremic Syndrome and Escherichia coli O121 at a Lake in Connecticut, 1999T A McCarthy
Epidemic Intelligence Service, Connecticut Department of Public Health, Epidemiology Program Office, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Pediatrics 108:E59. 2001Non-O157 Shiga toxin-producing Escherichia coli (STEC) have emerged as an important public health problem. Outbreaks attributed to non-O157 STEC rarely are reported...
Evaluation of techniques for enrichment and isolation of Escherichia coli O157:H7 from artificially contaminated sproutsS D Weagant
Pacific Regional Laboratory Northwest, US Food and Drug Administration, Bothell, WA 98021, USA
Int J Food Microbiol 71:87-92. 2001..have high levels of nutrients, and a neutral pH, they are subject to the outgrowth of pathogens such as Escherichia coli O157:H7...
[Antibacterial actin of vinegar against food-borne pathogenic bacteria including Escherichia coli O157:H7 (Part 2). Effect of sodium chloride and temperature on bactericidal activity]E Entani
Nakano Central Research Institute of Nakano Vinegar Co. Ltd
Kansenshogaku Zasshi 71:451-8. 1997..5% acidity) on food-borne pathogenic bacteria including Escherichia coli O157:H7 and other bacteria were examined. the order of bactericidal activities was NIHAIZU (3...
Impact of empiric antimicrobial therapy on outcomes in patients with Escherichia coli and Klebsiella pneumoniae bacteremia: a cohort studyKerri A Thom
Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD, USA
BMC Infect Dis 8:116. 2008..whether appropriate empiric antimicrobial therapy improves outcomes in patients with bacteremia due to Escherichia coli or Klebsiella...
Asparagine 394 in putative helix 11 of the galactose-H+ symport protein (GalP) from Escherichia coli is associated with the internal binding site for cytochalasin B and sugarT P McDonald
Department of Biochemistry and Molecular Biology, University of Leeds, Leeds, LS2 9JT, United Kingdom
J Biol Chem 272:15189-99. 1997The galactose-H+ symport protein (GalP) of Escherichia coli is very similar to the human glucose transport protein, GLUT1, and both contain a highly conserved Asn residue in predicted helix 11 that is different in a cytochalasin B-..
Prevalence of enteropathogenic Escherichia coli in naturally occurring cases of poult enteritis-mortality syndromeS Pakpinyo
Department of Farm Animal Health and Resource Management, College of Veterinary Medicine, North Carolina State University, Raleigh 27606, USA
Avian Dis 46:360-9. 2002Enteropathogenic Escherichia coli (EPEC) previously were identified in poult enteritis-mortality syndrome (PEMS)-affected turkeys and associated as a cause of this disease...
[Investigation of bactericidal effect and nitric oxide responses of Caco-2 epithelial cells and THP-1 macrophage cells against Streptococcus pyogenes and Escherichia coli]Derya Biriken Salin
Ankara Üniversitesi Tıp Fakültesi, Mikrobiyoloji ve Klinik Mikrobiyoloji Anabilim Dali, Ankara
Mikrobiyol Bul 43:373-81. 2009..Therefore, Streptococcus pyogenes and Escherichia coli activated Caco-2 cells and THP-1 macrophage-like cells were investigated for their bactericidal activities ..
Growth performance and gastrointestinal microbial ecology responses of piglets receiving Saccharomyces cerevisiae fermentation products after an oral challenge with Escherichia coli (K88)E Kiarie
Department of Animal Science, Winnipeg, Manitoba R3T 2N2, Canada
J Anim Sci 89:1062-78. 2011..on growth performance and gastrointestinal (GIT) microbial ecology in 90 weanling pigs orally challenged with Escherichia coli K88(+) (ETEC) were investigated...
Rare codon content affects the solubility of recombinant proteins in a codon bias-adjusted Escherichia coli strainGermán L Rosano
Molecular Biology Division, Instituto de Biologia Molecular y Celular de Rosario IBR, CONICET, Facultad de Ciencias Bioquimicas y Farmaceuticas, Universidad Nacional de Rosario, Suipacha 531, S2002LRK Rosario, Argentina
Microb Cell Fact 8:41. 2009..abstract:..
Modeling the survival of Escherichia coli O157:H7, Listeria monocytogenes, and Salmonella Typhimurium during fermentation, drying, and storage of soudjouk-style fermented sausageCheng An Hwang
Microbial Food Safety Research Unit, Eastern Regional Research Center, Agricultural Research Service, U S Department of Agriculture, 600 E Mermaid Lane, Wyndmoor, PA 19038, USA
Int J Food Microbiol 129:244-52. 2009This study quantified and modeled the survival of Escherichia coli O157:H7, Listeria monocytogenes and Salmonella Typhimurium in soudjouk-style fermented sausage during fermentation, drying, and storage...
On the multiple functional roles of the active site histidine in catalysis and allosteric regulation of Escherichia coli glucosamine 6-phosphate deaminaseG M Montero-Morán
Departamento de Bioquimica, Laboratorio de Fisicoquímica y Diseño de Proteínas, Facultad de Medicina, Universidad Nacional Autonoma de Mexico UNAM, P O Box 70 159, Mexico City 04510, D F, Mexico
Biochemistry 40:10187-96. 2001The active site of glucosamine-6-phosphate deaminase (EC 3.5.99.6, formerly 5.3.1.10) from Escherichia coli was first characterized on the basis of the crystallographic structure of the enzyme bound to the competitive inhibitor 2-amino-2-..
Quantitative resistance level (MIC) of bacterial pathogens (Escherichia coli, Pasteurella multocida, Pseudomonas aeruginosa, Salmonella sp., Staphylococcus aureus) isolated from chickens and turkeys: national resistance monitoring by the BVL 2004/2005Jürgen Wallmann
Federal Office of Consumer Protection and Food Safety BVL, Berlin, Germany
Berl Munch Tierarztl Wochenschr 120:452-63. 2007In the study 2004/2005, the current quantitative resistance level of Escherichia coli, Pasteurella multocida, Pseudomonas aeruginosa, Salmonella sp...
Influence of colostrum deprivation and concurrent Cryptosporidium parvum infection on the colonization and persistence of Escherichia coli O157 : H7 in young lambsR M La Ragione
Department of Food and Environmental Safety, Veterinary Laboratories Agency Weybridge, Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK
J Med Microbiol 55:819-28. 2006b>Escherichia coli O157 : H7 and Cryptosporidium parvum infections of man have been associated with direct contact with small ruminants...
Mechanism of carbamoyl phosphate synthetase from Escherichia coli--binding of the ATP molecules used in the reaction and sequestration by the enzyme of the ATP molecule that yields carbamoyl phosphateV Rubio
Instituto de Investigaciones Citológicas FVIB CSIC, Valencia, Spain
Eur J Biochem 255:262-70. 1998..of ATP that are involved in the overall reaction catalyzed by carbamoyl-phosphate synthetase (CPS) of Escherichia coli, and a mechanism recently proposed for this reaction, has led us to reexamine ATP binding using pulse/chase ..
Role of Asp222 in the catalytic mechanism of Escherichia coli aspartate aminotransferase: the amino acid residue which enhances the function of the enzyme-bound coenzyme pyridoxal 5'-phosphateT Yano
Department of Medical Chemistry, Osaka Medical College, Japan
Biochemistry 31:5878-87. 1992..This residue of Escherichia coli aspartate aminotransferase was replaced by Ala, Asn, or Glu by site-directed mutagenesis...
RNA chain initiation by Escherichia coli RNA polymerase. Structural transitions of the enzyme in early ternary complexesB Krummel
Department of Biochemistry, University of California, Berkeley 94720
Biochemistry 28:7829-42. 1989We have studied the properties and structures of a series of Escherichia coli RNA polymerase ternary complexes formed during the initial steps of RNA chain initiation and elongation...
Transport of Escherichia coli in 25 m quartz sand columnsG Lutterodt
UNESCO IHE Institute for Water Education, P O Box 3015, 2601 DA Delft, The Netherlands
J Contam Hydrol 119:80-8. 2011..experiments were conducted to measure the distant dependent sticking efficiencies of two low attaching Escherichia coli strains (UCFL-94 and UCFL-131)...
Influence of dietary endophyte (Neotyphodium coenophialum)-infected tall fescue (Festuca arundinacea) seed on fecal shedding of antibiotic resistance-selected Escherichia coli O157:H7 in ewesM L Looper
USDA ARS, Dale Bumpers Small Farms Research Center, Booneville, AR 72927, USA
J Anim Sci 85:1102-8. 2007..fescue seed (Festuca arundinacea, cultivar 'Kentucky 31') on fecal shedding and intestinal concentrations of Escherichia coli O157:H7 and the concentrations of prolactin, cortisol, and NEFA in experimentally inoculated ewes...
Evaluation of the NCCLS extended-spectrum beta-lactamase confirmation methods for Escherichia coli with isolates collected during Project ICAREFred C Tenover
Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Clin Microbiol 41:3142-6. 2003To determine whether confirmatory tests for extended-spectrum beta-lactamase (ESBL) production in Escherichia coli are necessary, we selected 131 E...
Kinetic mechanism of adenine nucleotide binding to and hydrolysis by the Escherichia coli Rep monomer. 2. Application of a kinetic competition approachK J Moore
Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St Louis, Missouri 63110
Biochemistry 33:14565-78. 1994The Escherichia coli Rep protein is a DNA helicase that functions as a homodimer to catalyze the unwinding of duplex DNA during DNA replication in a reaction that is coupled to the binding and hydrolysis of ATP...
Serotypes, virulence genes and intimin types of Shiga toxin (verocytotoxin)-producing Escherichia coli isolates from minced beef in Lugo (Spain) from 1995 through 2003Azucena Mora
Laboratorio de Referencia de E coli, Departamento de Microbioloxia e Parasitoloxia, Universidade de Santiago de Compostela USC, 27002 Lugo, Spain
BMC Microbiol 7:13. 2007Shiga toxin-producing Escherichia coli (STEC) have emerged as pathogens that can cause food-borne infections and severe and potentially fatal illnesses in humans, such as haemorrhagic colitis (HC) and haemolytic uraemic syndrome (HUS)...
Escherichia coli lipoyl synthase binds two distinct [4Fe-4S] clusters per polypeptideRobert M Cicchillo
Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
Biochemistry 43:11770-81. 2004..However, the exact identity of the sulfur donor remains unknown. We report herein that LS from Escherichia coli can accommodate two [4Fe-4S] clusters per polypeptide and that this form of the enzyme is relevant to ..
[Evolution of Escherichia coli antibiotic resistances in urine samples from the community]Jose Maria Sanchez Merino
Servicio de Urologia, Hospital El Bierzo, Ponferrada, Leon, Espana
Arch Esp Urol 61:776-80. 2008The objectives of this work are two: first, to evaluate the resistance of Escherichia coli to several antibiotics and their trends over a six-year period in strands isolated in urine samples from patients receiving health-care in general ..
Control of Escherichia coli O157:H7 in corn silage with or without various inoculants: efficacy and mode of actionA F Pedroso
Department of Animal Sciences, Institute of Food and Agricultural Sciences, University of Florida, Gainesville 32606, USA
J Dairy Sci 93:1098-104. 2010This study aimed to evaluate the effectiveness of 3 commercial bacterial inoculants at controlling Escherichia coli O157:H7 in corn silages during ensiling and feedout phases of silage production...
Multiple seropathotypes of verotoxin-producing Escherichia coli (VTEC) disrupt interferon-gamma-induced tyrosine phosphorylation of signal transducer and activator of transcription (Stat)-1Narveen Jandu
Research Institute, Hospital for Sick Children, Ont, Canada
Microb Pathog 42:62-71. 2007Verotoxin-producing Escherichia coli (VTEC) O157:H7 inhibits interferon-gamma-stimulated tyrosine phosphorylation of signal transducer and activator of transcription (Stat)-1 in epithelial cells, independent of Verotoxins and the locus of ..
Differential effects of temperature and hydrostatic pressure on the formation of quinonoid intermediates from L-Trp and L-Met by H463F mutant Escherichia coli tryptophan indole-lyaseRobert S Phillips
Department of Chemistry, University of Georgia, Athens, Georgia 30602 2556, USA
Biochemistry 44:14289-97. 2005b>Escherichia coli tryptophan indole-lyase (Trpase) is a bacterial pyridoxal 5'-phosphate (PLP)-dependent enzyme which catalyzes the reversible beta-elimination of l-Trp to give indole and ammonium pyruvate. H463F mutant E...
A mechanism for toxin insertion into membranes is suggested by the crystal structure of the channel-forming domain of colicin E1P Elkins
Protein Engineering, Department Genentech, Inc 460 Pt San Bruno Blvd, South San Francisco, CA 94080, USA
Structure 5:443-58. 1997..ability to form a voltage-gated channel, which causes depolarization of the cytoplasmic membrane of sensitive Escherichia coli cells...
The arginine repressor is essential for plasmid-stabilizing site-specific recombination at the ColE1 cer locusC J Stirling
Institute of Genetics, University of Glasgow, UK
EMBO J 7:4389-95. 1988The heritable stability in Escherichia coli of the multicopy plasmid ColE1 and its natural relatives requires that the plasmids be maintained in the monomeric state...
The nucleotide sequence surrounding the promoter region of colicin E1 geneY Ebina
Gene 15:119-26. 1981..These data indicate the existence of two promoters, one of which is located in the coding region for colicin E1. DNA sequence homology of 16 bp was found between the putative operator regions of the colicin E1 and recA genes...
Clinical Escherichia coli isolates utilize alpha-hemolysin to inhibit in vitro epithelial cytokine productionDavid W Hilbert
Femeris Women s Health Research Center, Medical Diagnostic Laboratories LLC, 2439 Kuser Rd, Hamilton, NJ 08690, USA
Microbes Infect 14:628-38. 2012Uropathogenic Escherichia coli is the primary cause of urinary tract infections, which affects over 60% of women during their lifetime...
The effect of NAPRTase overexpression on the total levels of NAD, the NADH/NAD+ ratio, and the distribution of metabolites in Escherichia coliSusana J Berríos-Rivera
Department of Bioengineering and Chemical Engineering, Rice University, 6100 Main Street, MS 142, Houston, Texas 77005 1892, USA
Metab Eng 4:238-47. 2002b>Escherichia coli (E. coli) maintains its total NADH/NAD+ intracellular pool by synthesizing NAD through the de novo pathway and the pyridine nucleotide salvage pathway...
OmpT outer membrane proteases of enterohemorrhagic and enteropathogenic Escherichia coli contribute differently to the degradation of human LL-37Jenny Lee Thomassin
Department of Microbiology and Immunology, McGill University, Montreal, QC, Canada
Infect Immun 80:483-92. 2012Enterohemorrhagic Escherichia coli (EHEC) and enteropathogenic E. coli (EPEC) are food-borne pathogens that cause serious diarrheal diseases...
False extended-spectrum {beta}-lactamase phenotype in clinical isolates of Escherichia coli associated with increased expression of OXA-1 or TEM-1 penicillinases and loss of porinsAlejandro Beceiro
Health Protection Agency, Microbiology Services Colindale, London, UK
J Antimicrob Chemother 66:2006-10. 2011Two clinical isolates of Escherichia coli, EC18 and EC21, were non-susceptible (MICs 4-16 mg/L) to cefpirome and cefepime, with marked synergy with clavulanate, yet were susceptible to cefotaxime and ceftazidime (MICs ≤ 1 mg/L)...
Structural consequences of ATP hydrolysis on the ABC transporter NBD dimer: molecular dynamics studies of HlyBJoão M Damas
Instituto de Tecnologia Quimica e Biologica, Universidade Nova de Lisboa, Oeiras, Portugal
Protein Sci 20:1220-30. 2011..We propose that this motif is an important part of the NBD-TMD communication in ABC exporters. Through nonequilibrium analysis, we have also identified gradual conformational changes within a short time scale after ATP hydrolysis...
Mutation of the active site carboxy-lysine (K70) of OXA-1 beta-lactamase results in a deacylation-deficient enzymeKyle D Schneider
Department of Chemistry, Grand Valley State University, Allendale, Michigan 49401, USA
Biochemistry 48:6136-45. 2009..In conclusion, we establish the functional role of the carboxylated lysine in OXA-1 and highlight its specific role in acylation and deacylation...
Characterization of methicillin-resistant Staphylococcus aureus, vancomycin-resistant enterococci and extended-spectrum beta-lactamase-producing Escherichia coli in intensive care units in Canada: Results of the Canadian National Intensive Care Unit (CAN-George G Zhanel
Department of Medical Microbiology, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba
Can J Infect Dis Med Microbiol 19:243-9. 2008Methicillin-resistant Staphylococcus aureus (MRSA), extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli and vancomycin-resistant enterococci (VRE) are important hospital pathogens in Canada and worldwide.
Campylobacter, Salmonella, Listeria monocytogenes, verotoxigenic Escherichia coli, and Escherichia coli prevalence, enumeration, and subtypes on retail chicken breasts with and without skinAngela Cook
Laboratory for Foodborne Zoonoses, Public Health Agency of Canada, 255 Woodlawn Road West, Unit 120, Guelph, Ontario, Canada N1H 8J1
J Food Prot 75:34-40. 2012..the prevalence, counts, and subtypes of Campylobacter, Salmonella, Listeria monocytogenes, verotoxigenic Escherichia coli (VTEC), and E. coli on raw retail chicken breast with the skin on versus the skin off...
Loopless Rop: structure and dynamics of an engineered homotetrameric variant of the repressor of primer proteinNicholas M Glykos
Department of Molecular Biology and Genetics, Democritus University of Thrace, Dimitras 19, 68100 Alexandroupolis, Greece
Biochemistry 45:10905-19. 2006..Additional insight into the stability and dynamics of the mutant structure has been obtained from extensive molecular dynamics simulations in explicit water and with full treatment of electrostatics...
Urodilatin and pentoxifylline prevent the early onset of Escherichia coli-induced acute renal failure in a model of isolated perfused rat kidneyHeinrich V Groesdonk
Department of Anesthesiology, University of Lubeck, Lubeck, Germany
Kidney Blood Press Res 32:81-90. 2009..Methods: Eight series of experiments were performed: no intervention, perfusion with a suspension containing Escherichia coli bacteria (strain 536/21); E. coli + 10 microg/l urodilatin, E. coli + 20 microg/l urodilatin, E...
Administration of Pediococcus acidilactici or Saccharomyces cerevisiae boulardii modulates development of porcine mucosal immunity and reduces intestinal bacterial translocation after Escherichia coli challengeM Lessard
Dairy and Swine Research and Development Centre, Agriculture and Agri Food Canada, Sherbrooke, Quebec, Canada
J Anim Sci 87:922-34. 2009..and Saccharomyces cerevisiae boulardii (SCB), on intestinal immune traits and resistance to enterotoxigenic Escherichia coli (ETEC) infection was evaluated in pigs...
L-Sorbose utilization by virulent Escherichia coli and Shigella: different metabolic adaptation of pathotypesAnselm Lehmacher
Institut für Hygiene und Umwelt, Abteilung Mikrobiologischer Verbraucherschutz, Marckmannstrasse 129a, D 20539 Hamburg, Germany
Int J Med Microbiol 297:245-54. 2007The frequency of L-Sorbose utilization differs significantly between pathotypes of Escherichia coli and Shigella from 93% to 0%. Among 266 strains tested, this frequency increased in the order Shigella, enterotoxigenic E...
[Antimicrobial resistance of Escherichia coli isolated from different samples in children]Hai Jiao Zhu
People s Hospital of Qingtian, Qingtian, Zhejiang, China
Zhongguo Dang Dai Er Ke Za Zhi 12:348-50. 2010To investigate the possible differences in antimicrobial resistance of Escherichia coli isolated from different samples in children.
Evaluation of alternatives to antibiotics using an Escherichia coli K88+ model of piglet diarrhea: effects on gut microbial ecologyS K Bhandari
Department of Animal Science, University of Manitoba, Winnipeg, Manitoba R3T 2N2 Canada
J Anim Sci 86:836-47. 2008Enterotoxigenic Escherichia coli is a major problem in the swine industry and results in scouring, increased mortality, and poor performance in the period immediately postweaning...
Common origin of plasmid encoded alpha-hemolysin genes in Escherichia coliYlanna Burgos
Federal Institute for Risk Assessment, Berlin, Germany
BMC Microbiol 10:193. 2010..coli (UPEC), the alpha-hly genes are located on chromosomal pathogenicity islands. Previous work suggested that plasmid and chromosomally encoded alpha-hly may have evolved independently. This was explored in our study...
Global transcriptional response of Escherichia coli O157:H7 to growth transitions in glucose minimal mediumTeresa M Bergholz
Microbial Evolution Laboratory, National Food Safety and Toxicology Center, Michigan State University, East Lansing, Michigan 48824, USA
BMC Microbiol 7:97. 2007Global patterns of gene expression of Escherichia coli K-12 during growth transitions have been deeply investigated, however, comparable studies of E...
Importance of the region around lysine 196 for catalytic activity of adenylyl cyclase from Escherichia coliN Amin
Laboratory of Biochemical Genetics, NHLBI, National Institutes of Health, Bethesda, Maryland 20892
J Biol Chem 269:31074-9. 1994b>Escherichia coli adenylyl cyclase contains no sequence that corresponds to the previously defined ATP/GTP binding consensus (A,G)XXXXGK(S,T)...
The contribution of small cryptic plasmids to the antibiotic resistance of enteropathogenic Escherichia coli E2348/69Cynthia L Handford
Department of Biological Sciences, University of Alberta, Edmonton, AB T6G 2E9, Canada
Can J Microbiol 55:1229-39. 2009Two uncharacterized small cryptic plasmids (SCPs) were isolated from enteropathogenic Escherichia coli strain E2348/69...
Comparison of methods for detection and isolation of cold- and freeze-stressed Escherichia coli O157:H7 in raw ground beefPina M Fratamico
US Department of Agriculture, Agricultural Research Service, Eastern Regional Research Center, 600 East Mermaid Lane, Wyndmoor, Pennsylvania 19038, USA
J Food Prot 70:1663-9. 2007A comparison was made of the relative efficiencies of three enrichment media, RapidChek Escherichia coli O157:H7 enrichment broth (REB), R&F broth (RFB), and modified E...
Genetic characteristics and antimicrobial resistance of Escherichia coli from Japanese macaques (Macaca fuscata) in rural JapanKeiko Ogawa
School of Veterinary Medicine, Hokkaido University, Kita 18, Nishi 9, Kita ku, Sapporo, Hokkaido 060 0818, Japan
J Wildl Dis 47:261-70. 2011b>Escherichia coli was isolated from wild and captive Japanese macaques (Macaca fuscata) to investigate the risk of zoonotic infections and the prevalence of antimicrobial-resistant Escherichia coli in the wild macaque population in ..
Antimicrobial susceptibility of clinical Escherichia coli isolates from uncomplicated cystitis in women over a 1-year period in SpainM Gobernado
Department of Microbiology, University Hospital La Fe, Valencia, Spain
Rev Esp Quimioter 20:68-76. 2007High usage of antibiotics in Spain has led to an increase in resistance in urinary Escherichia coli isolates in different geographic regions. The problem of resistance in urinary E...
Effect of tannins on the in vitro growth of Escherichia coli O157:H7 and in vivo growth of generic Escherichia coli excreted from steersEng R Min
Texas Agricultural Experiment Station, P O Box 1658, Vernon, Texas 76385, USA
J Food Prot 70:543-50. 2007..chestnut and mimosa tannins in vitro (experiment 1) or in vivo (experiment 2) on the growth or recovery of Escherichia coli O157:H7 or generic fecal E. coli was evaluated. In experiment 1, the mean growth rate of E...
Prevalence of urovirulence genes cnf, hlyD, sfa/foc, and papGIII in fecal Escherichia coli from healthy dogs and their ownersKatherine A Stenske
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, TN 37996, USA
Am J Vet Res 70:1401-6. 2009To determine the prevalence of 4 urovirulence genes in fecal Escherichia coli isolates from healthy dogs and their owners and to determine whether detection of E coli strains with these genes was associated with a history of urinary tract ..
Chimeras of Escherichia coli and Mycobacterium tuberculosis single-stranded DNA binding proteins: characterization and function in Escherichia coliSanjay Kumar Bharti
Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, India
PLoS ONE 6:e27216. 2011..Studies on SSBs from the prototype, Escherichia coli (EcoSSB) and, an important human pathogen, Mycobacterium tuberculosis (MtuSSB) had shown that despite ..
Characterization of the F plasmid mating aggregation gene traN and of a new F transfer region locus trbES Maneewannakul
Department of Medical Microbiology and Immunology, Texas A and M University, College Station 77843
J Mol Biol 225:299-311. 1992..The mating efficiency and pilus-specific phage susceptibility of a trbE::kan insertion mutant suggested that trbE is not essential for F transfer from Escherichia coli K-12 under standard mating conditions.
Identification of N,N'-dicyclohexylcarbodiimide-reactive glutamic and aspartic acid residues in Escherichia coli transhydrogenase and the exchange of these by site-specific mutagenesisN Glavas
Department of Biochemistry, University of British Columbia, Vancouver, Canada
J Biol Chem 268:14125-30. 1993Pyridine nucleotide transhydrogenase (EC 1.6.1.1) from Escherichia coli was investigated with respect to the role of glutamic and aspartic acid residues reactive to N,N'-dicyclohexylcarbodiimide (DCCD) and potentially involved in the ..
Folding pathway of Escherichia coli ribonuclease HI: a circular dichroism, fluorescence, and NMR studyK Yamasaki
Protein Engineering Research Institute, Osaka, Japan
Biochemistry 34:16552-62. 1995The unfolding and refolding processes of Escherichia coli ribonuclease HI at 25 degrees C, induced by concentration jumps of either guanidine hydrochloride (GuHCl) or urea, were investigated using stopped-flow circular dichroism (CD), ..
Plasmid coding for drug resistance and invasion of epithelial cells in enteropathogenic Escherichia coli 0111:HI C Scaletsky
Department of Microbiology, Immunology and Parasitology, Escola Paulista de Medicina, Sao Paulo, Brazil
Microb Pathog 18:387-99. 1995Enteropathogenic Escherichia coli (EPEC) can adhere to, invade and multiply in human epithelial cells. To define the elements required for bacterial invasion, we isolated from an 0111:H- EPEC a 6...
Polymorphism, duplication, and IS1-mediated rearrangement in the chromosomal his-rfb-gnd region of Escherichia coli strains with group IA and capsular K antigensJ Drummelsmith
Department of Microbiology, University of Guelph, Ontario, Canada
J Bacteriol 179:3232-8. 1997Individual Escherichia coli strains produce several cell surface polysaccharides. In E...
Parameters of bacterial killing and regrowth kinetics and antimicrobial effect examined in terms of area under the concentration-time curve relationships: action of ciprofloxacin against Escherichia coli in an in vitro dynamic modelA A Firsov
Department of Pharmacokinetics, Centre of Science and Technology, LekBioTech, Moscow, Russia
Antimicrob Agents Chemother 41:1281-7. 1997..To examine different parameters, the kinetics of killing and regrowth of Escherichia coli (MIC, 0...
Research Grants
- S. typhimiurium Vaccine Against Bacterial EnteropathogensRoy Curtiss; Fiscal Year: 2007..2 million are the result of infections by Salmonella and other related bacterial enteropathogens including Escherichia coli and Shigella species, and less closely related enteropathogens such as Vibrio cholerae, Campylobacter jejuni ..
- Electrochemical Method for Viable Pathogen DetectionADRIAN DENVIR; Fiscal Year: 2006..is to develop a new, automated system for the rapid detection of bacterial contamination (especially Escherichia coli O157:H7) in meat and meat products...
- Salmonella Vaccines Against Bacterial EnteropathogensRoy Curtiss; Fiscal Year: 2010..8 (WHO) to 2.2 (UNESCO) million are due to infections with enteric pathogens including Salmonella, Escherichia coli and Shigella sp., and other entero-pathogens such as Yersinia sp...
- Colitis Induced by immune responses to luminal bacteria-mouseRYAN BALFOUR SARTOR; Fiscal Year: 2010..Selective colonization of germ-free IL-10-/- mice with Escherichia coli or Enterococcus faecalis induces different phenotypes of colitis for each bacteria. E. coli and E...
- ANALYSIS OF THE E COLI HEMOLYSIN AND RELATED TOXINSRODNEY WELCH; Fiscal Year: 1993A family of exotoxins (RTX) produced by a variety of important human and animal pathogens, such as Escherichia coli, Bordetella pertussis, Actinobacillus actinomycetemcomitans and Pasteurella haemolytica has been recently recognized...
- SHIGA-LIKE TOXIN OF ESCHERICHIA COLIALISON O BRIEN; Fiscal Year: 1992b>Escherichia coli can cause diarrhea by several distinct mechanisms. A newly recognized group of E. coli cause hemorrhagic colitis and the hemolytic uremic syndrome. These enterohemorrhagic E...
- REGULATION OF LIPID METABOLISM IN BACTERIACharles O Rock; Fiscal Year: 2011..The basic blueprint for bacterial membrane lipid biosynthesis is established by decades of research with Escherichia coli. However, there are numerous and significant differences in lipid metabolism between Gram-positive and Gram-..
- Reciprocal Control of Motility and Adherence in UTIHarry L Mobley; Fiscal Year: 2010..The most common uropathogen, Escherichia coli, can cause acute cystitis or pyelonephritis in the uncomplicated urinary tract...
- REGULATION BY THE ESCHERICHIA COLI SMALL RNA, DSRADARREN SLEDJESKI; Fiscal Year: 2002DsrA is a small, stable, untranslated RNA that is conserved between Escherichia coli, Klebsiella pneumoniae, and Salmonella typhimurium. DsrA RNA regulates two different global regulatory networks...
- URACIL/DNA REPAIR IN VITRO AND IN VIVODALE MOSBAUGH; Fiscal Year: 1999..to extend their investigations concerning the mechanism and enzymology of uracil-DNA repair in human and Escherichia coli cells...
- BIOSYNTHESIS AND FUNCTION OF LIPOPOLYSACCHARIDESCHRISTIAN R RAETZ; Fiscal Year: 2010..b>Escherichia coli lipid A is synthesized on the cytoplasmic surface of the inner membrane by a conserved pathway of nine ..
- LIPID A MODIFICATION SYSTEMS IN GRAM-NEGATIVE BACTERIACHRISTIAN RAETZ; Fiscal Year: 2009..b>Escherichia coli lipid A is synthesized on the cytoplasmic surface of the inner membrane by a conserved pathway of nine ..
- LIPID A MODIFICATION SYSTEMS IN GRAM-NEGATIVE BACTERIACHRISTIAN R RAETZ; Fiscal Year: 2010..b>Escherichia coli lipid A is synthesized on the cytoplasmic surface of the inner membrane by a conserved pathway of nine ..
- Physiological response of Escherichia coli to temperature and desiccation stressSusan Bornstein Forst; Fiscal Year: 2006..In order to validate use of Escherichia coli (E...
- Peptidoglycan Biogenesis in Escherichia ColiThomas G Bernhardt; Fiscal Year: 2010....
- Pathogenicity of Shiga Toxin-Producing E. coliALISON O BRIEN; Fiscal Year: 2007Enterohemorrhagic Escherichia coli (EHEC) O157:H7 belongs to a subset of Shiga toxin-producing E coli (STEC) that makes Shiga toxin (Stx) type 1 or type 2 (or a variant thereof), or both toxins, harbors pO157 (or a related plasmid) and ..
- Capsule conjugate vaccines against ETEC and CampylobacterPatricia Guerry; Fiscal Year: 2010..The hypothesis of this proposal is that multivalent vaccines can be generated against enterotoxigenic Escherichia coli (ETEC) and Campylobacter jejuni by conjugation of LTB and antigenically distinct colonization factor antigens ..
- DNA METHYLATION AND PILI GENE REGULATIONDavid Low; Fiscal Year: 2006..and PapI orchestrate the reversible switch between OFF and ON Pap pili expression states in uropathogenic Escherichia coli (UPEC)...
- GENETIC ANALYSIS OF CHOLERA TOXIN STRUCTURE AND FUNCTIONRandall Holmes; Fiscal Year: 2007..Cholera caused by Vibrio cholerae and watery diarrhea caused by enterotoxigenic Escherichia coli (ETEC) cause substantial morbidity and mortality worldwide, and ETEC accounts for up to 20% of diarrhea cases ..
- Maneuvering of Macrophage Function By Escherichia coli K1PRASADARAO V NEMANI; Fiscal Year: 2010Bacterial meningitis due to Escherichia coli K1 is a serious illness of the central nervous system. It is the most common pathogen causing meningitis in premature infants (46%)...
- Rho-Modifying Cytotoxic Necrotizing Factor of E. coliALISON O BRIEN; Fiscal Year: 2009..CNF1 and a membrane-lytic toxin, hemolysin (Hly), are often coexpressed by Escherichia coli strains that cause urinary tract infections (UTIs), i.e., cystitis or pyelonephritis, or acute prostatitis...
- E COLI TRANSLOCATION ACROSS INTESTINAL EPITHELIUMMichelle Pietzak; Fiscal Year: 2003..D., Dr. Pietzak will continue to pursue her basic investigations into the mechanisms by which Escherichia coli (E. coli) is able to translocate across intestinal epithelium and cause sepsis. E...
- Topoisomerases and Chromosome SegregationKENNETH MARIANS; Fiscal Year: 2009..term goal of this grant is to understand the events necessary for proper segregation of the newly duplicated Escherichia coli sister chromosomes to a new daughter cell...
- VIRUL FACTORS OF UROPATH ESCHERICHIA COLIPeter Redford; Fiscal Year: 2003b>Escherichia coli is the most common cause of community-acquired urinary tract infections, resulting in an estimated eight million physician visits a year in the United States. It is also a leading cause of nosocomial infections...
- Engineering Large scale pathways from organisms to Escherichia coliJames Liao; Fiscal Year: 2007..technologies for transferring large gene clusters (30-300 kb) from a distantly related microorganism to Escherichia coli such that an entire metabolic pathway can be grafted to the host...
- Regulation of the Poly Sialic Virulence FactorERIC ROSS VIMR; Fiscal Year: 2010Extraintestinal pathogenic Escherichia coli (ExPEC) are major pathogens in mostly the very young, aged or immunocompromised human population resulting in tens of thousands of deaths each year and billions of dollars in healthcare costs...
