Coxiella burnetii

Summary

Alias: "Rickettsia burneti" (sic) Derrick 1939, "Rickettsia diaporica" Cox 1939, Coxiella burnetii (Derrick 1939) Philip 1948, Rickettsia burneti, Rickettsia diaporica, Coxiella burnetii8

Top Publications

  1. Liu J, Ochieng C, Wiersma S, Ströher U, Towner J, Whitmer S, et al. Development of a TaqMan Array Card for Acute-Febrile-Illness Outbreak Investigation and Surveillance of Emerging Pathogens, Including Ebola Virus. J Clin Microbiol. 2016;54:49-58 pubmed publisher
    ..Brucella spp., Coxiella burnetii, Leptospira spp., Rickettsia spp...
  2. Wang H, Wu S, Jiang L, Xiao R, Li T, Mei L, et al. Establishment and optimization of a liquid bead array for the simultaneous detection of ten insect-borne pathogens. Parasit Vectors. 2018;11:442 pubmed publisher
    ..acid of 10 insect-borne pathogens, including Bluetongue virus, Epizootic hemorrhagic disease virus of deer, Coxiella burnetii, African swine fever virus, West Nile fever virus, Borrelia burgdorferi, vesicular stomatitis virus, Rift ..
  3. Lau C, Musso D, Fournier P, Parola P, Raoult D, Weinstein P. Absence of serological evidence of Rickettsia spp., Bartonella spp., Ehrlichia spp. and Coxiella burnetii infections in American Samoa. Ticks Tick Borne Dis. 2016;7:703-705 pubmed publisher
    ..Bartonella spp., Ehrlichia spp. or Coxiella burnetii infections in this country...
  4. Tavernier P, Sys S, De Clercq K, De Leeuw I, Caij A, De Baere M, et al. Serologic screening for 13 infectious agents in roe deer (Capreolus capreolus) in Flanders. Infect Ecol Epidemiol. 2015;5:29862 pubmed publisher
    ..1%). The lowest prevalences were found for Leptospira (1.7%), bovine viral diarrhoea virus 1 (1.3%), and Coxiella burnetii (1.2%). No antibodies were found against Brucella sp., bovine herpesvirus 1, and bluetongue virus...
  5. Kanouté Y, Gragnon B, Schindler C, Bonfoh B, Schelling E. Epidemiology of brucellosis, Q Fever and Rift Valley Fever at the human and livestock interface in northern Côte d'Ivoire. Acta Trop. 2017;165:66-75 pubmed publisher
    ..indirect and competitive ELISAs, Coxiella burnetii indirect ELISA and RVF competitive ELISA. The human seroprevalence for Brucella spp. was 5.3%...
  6. Kanouté Y, Gragnon B, Schindler C, Bonfoh B, Schelling E. Reprint of "Epidemiology of brucellosis, Q Fever and Rift Valley Fever at the human and livestock interface in northern Côte d'Ivoire". Acta Trop. 2017;175:121-129 pubmed publisher
    ..indirect and competitive ELISAs, Coxiella burnetii indirect ELISA and RVF competitive ELISA. The human seroprevalence for Brucella spp. was 5.3%...
  7. van den Brom R, van Engelen E, Roest H, van der Hoek W, Vellema P. Coxiella burnetii infections in sheep or goats: an opinionated review. Vet Microbiol. 2015;181:119-29 pubmed publisher
    Q fever is an almost ubiquitous zoonosis caused by Coxiella burnetii, which is able to infect several animal species, as well as humans. Cattle, sheep and goats are the primary animal reservoirs...
  8. Graves S, Jackson C, Hussain Yusuf H, Vincent G, Nguyen C, Stenos J, et al. Ixodes holocyclus Tick-Transmitted Human Pathogens in North-Eastern New South Wales, Australia. Trop Med Infect Dis. 2016;1: pubmed publisher
    ..Five (36%) had antibodies to Coxiella burnetii, the causative agent of Q fever and three (21%) had antibodies to spotted fever group (SFG) rickettsiae (..
  9. Boone I, Henning K, Hilbert A, Neubauer H, von Kalckreuth V, Dekker D, et al. Are brucellosis, Q fever and melioidosis potential causes of febrile illness in Madagascar?. Acta Trop. 2017;172:255-262 pubmed publisher
    ..Therefore, the presence of Brucella spp., Coxiella burnetii and Burkholderia pseudomallei was investigated in Malagasy patients exhibiting febrile illness...

More Information

Publications303 found, 100 shown here

  1. Shapiro A, Brown G, Norris J, Bosward K, Marriot D, Balakrishnan N, et al. Vector-borne and zoonotic diseases of dogs in North-west New South Wales and the Northern Territory, Australia. BMC Vet Res. 2017;13:238 pubmed publisher
    ..serological screening for Coxiella burnetii, and Bartonella spp...
  2. Kuchuloria T, Imnadze P, Mamuchishvili N, Chokheli M, Tsertsvadze T, Endeladze M, et al. Hospital-Based Surveillance for Infectious Etiologies Among Patients with Acute Febrile Illness in Georgia, 2008-2011. Am J Trop Med Hyg. 2016;94:236-42 pubmed publisher
    ..Brucella spp., West Nile virus (WNV), Crimean-Congo hemorrhagic fever virus, Coxiella burnetii, tick-borne encephalitis virus (TBEV), hantavirus, Salmonella enterica serovar Typhi (S...
  3. Ardigò P, D incau M, Pongolini S. Abortion in cattle due to infection with Staphylococcus lugdunensis. J Vet Diagn Invest. 2014;26:818-20 pubmed publisher
    ..The serum was negative for Neospora caninum, Coxiella burnetii, Chlamydophila abortus, Bovine herpesvirus 1 (BHV-1), Bovine viral diarrhea virus (BVDV), Brucella abortus, ..
  4. Yu P, Niu Q, Liu Z, Yang J, Chen Z, Guan G, et al. Molecular epidemiological surveillance to assess emergence and re-emergence of tick-borne infections in tick samples from China evaluated by nested PCRs. Acta Trop. 2016;158:181-188 pubmed publisher
    ..Rickettsia spp., Babesia/Theileria spp., Ehrlichia ruminantium, Coxiella burnetii, and Francisella tularensis, using nested PCR assays and sequencing analysis...
  5. Fèvre E, de Glanville W, Thomas L, Cook E, Kariuki S, Wamae C. An integrated study of human and animal infectious disease in the Lake Victoria crescent small-holder crop-livestock production system, Kenya. BMC Infect Dis. 2017;17:457 pubmed publisher
    ..0.6% (95% CI 0.2-0.9); Coxiella burnetii, 2.2% (95% CI 1.5-2.9); Rift Valley fever, 0.5% (95% CI 0.2-0.8))...
  6. Bizzini A, Péter O, Baud D, Edouard S, Meylan P, Greub G. Evaluation of a new serological test for the detection of anti-Coxiella and anti-Rickettsia antibodies. Microbes Infect. 2015;17:811-6 pubmed publisher
    b>Coxiella burnetii and members of the genus Rickettsia are obligate intracellular bacteria. Since cultivation of these organisms requires dedicated techniques, their diagnosis usually relies on serological or molecular biology methods...
  7. Osimani A, Milanovic V, Cardinali F, Garofalo C, Clementi F, Pasquini M, et al. The bacterial biota of laboratory-reared edible mealworms (Tenebrio molitor L.): From feed to frass. Int J Food Microbiol. 2018;272:49-60 pubmed publisher
    ..Moreover, the occurrence of Coxiella burnetii, Pseudomonas aeruginosa and Shiga toxin-producing E...
  8. Wijnant G, Van Bocxlaer K, Yardley V, Murdan S, Croft S. Efficacy of Paromomycin-Chloroquine Combination Therapy in Experimental Cutaneous Leishmaniasis. Antimicrob Agents Chemother. 2017;61: pubmed publisher
    ..to cure chronic Q fever, as it enhances the activity of the antibiotic against the causative bacterium Coxiella burnetii residing within macrophage phagolysosomes...
  9. Millán J, Proboste T, Fernández de Mera I, Chirife A, de la Fuente J, Altet L. Molecular detection of vector-borne pathogens in wild and domestic carnivores and their ticks at the human-wildlife interface. Ticks Tick Borne Dis. 2016;7:284-90 pubmed publisher
    ..Anaplasmataceae, Coxiella burnetii, Bartonella spp., and Piroplasmida, and the amplicons were sequenced...
  10. Najdenski H, Dimova T, Zaharieva M, Nikolov B, Petrova Dinkova G, Dalakchieva S, et al. Migratory birds along the Mediterranean/Black Sea Flyway as carriers of zoonotic pathogens. Can J Microbiol. 2018;: pubmed publisher
    ..Yersinia, Salmonella, Listeria, Escherichia coli, Staphylococcus aureus, Francisella tularensis, Coxiella burnetii, Borrelia burgdorferi</i> and <i>Brucella</i> spp)...
  11. González Quijada S, Salazar Thieroldt E, Mora Simón M. Persistent Q fever and ischaemic stroke in elderly patients. Clin Microbiol Infect. 2015;21:362-7 pubmed publisher
    ..Phase I IgG titres against Coxiella burnetii ≥1:256 (compatible with chronic or persistent Q fever) were detected in 16 of 110 (14...
  12. Cumbassá A, Barahona M, Cunha M, Azórin B, Fonseca C, Rosalino L, et al. Coxiella burnetii DNA detected in domestic ruminants and wildlife from Portugal. Vet Microbiol. 2015;180:136-41 pubmed publisher
    b>Coxiella burnetii is the etiological agent of Q fever or Coxiellosis, a zoonosis mainly affecting domestic ruminants. Information on the population structure and epidemiology of C. burnetii in animals is scarce in Portugal. Evidence of C...
  13. Stead C, Cockrell D, Beare P, Miller H, Heinzen R. A Coxiella burnetii phospholipase A homolog pldA is required for optimal growth in macrophages and developmental form lipid remodeling. BMC Microbiol. 2018;18:33 pubmed publisher
    ..In the current study, we characterized a pldA mutant of Coxiella burnetii, an intracellular gram-negative pathogen and the agent of human Q fever. The C...
  14. Godinho I, Nogueira E, Santos C, Paulo S, Fortes A, Guerra J, et al. Chronic Q Fever in a renal transplant recipient: a case report. Transplant Proc. 2015;47:1045-7 pubmed publisher
    Q fever is a zoonosis caused by Coxiella burnetii that presents with a wide spectrum of acute and chronic manifestations...
  15. Prigent M, Rousset E, Yang E, Thiéry R, Sidi Boumedine K. Validation study for using lab-on-chip technology for Coxiella burnetii multi-locus-VNTR-analysis (MLVA) typing: application for studying genotypic diversity of strains from domestic ruminants in France. Microbes Infect. 2015;17:782-8 pubmed publisher
    b>Coxiella burnetii, the etiologic bacterium of Q fever zoonosis, is still difficult to control. Ruminants are often carriers and involved in human epidemics. MLVA is a promising genotyping method for molecular epidemiology...
  16. Isla A, Haussmann D, Vera T, Kausel G, Figueroa J. Identification of the clpB and bipA genes and an evaluation of their expression as related to intracellular survival for the bacterial pathogen Piscirickettsia salmonis. Vet Microbiol. 2014;173:390-4 pubmed publisher
    ..A number of studies have described the diverse proteins in pathogens such as Legionella pneumophila, Coxiella burnetii, and Francisella tularensis which allow these to evade the cellular immune response and replicate in the ..
  17. Vallejo Esquerra E, Yang H, Sanchez S, Omsland A. Physicochemical and Nutritional Requirements for Axenic Replication Suggest Physiological Basis for Coxiella burnetii Niche Restriction. Front Cell Infect Microbiol. 2017;7:190 pubmed publisher
    ..basis for niche restriction in the zoonotic bacterial obligate intracellular parasite and Q fever agent Coxiella burnetii are characterized. Additionally, these factors are reviewed in the context of C...
  18. Nielsen S, Nørskov Lauritsen N. Multispacer sequence typing of Coxiella burnetii DNA from removed prosthetic heart valve material discloses first human case of infective endocarditis caused by MST_18. Int J Infect Dis. 2019;79:139-141 pubmed publisher
    ..After identification of Coxiella burnetii, multispacer sequence typing (MST) was performed by PCR amplification of 10 intergenic sequences...
  19. Jiao J, Xiong X, Qi Y, Gong W, Duan C, Yang X, et al. Serological characterization of surface-exposed proteins of Coxiella burnetii. Microbiology. 2014;160:2718-31 pubmed publisher
    The obligate intracellular Gram-negative bacterium Coxiella burnetii causes Q fever, a worldwide zoonosis. Here we labelled Cox...
  20. Smith T, Driscoll T, Gillespie J, Raghavan R. A Coxiella-like endosymbiont is a potential vitamin source for the Lone Star tick. Genome Biol Evol. 2015;7:831-8 pubmed publisher
    ..A bacterium related to Coxiella burnetii, the agent of human Q fever, has been observed previously within cells of A. americanum...
  21. Rizzo F, Vitale N, Ballardini M, Borromeo V, Luzzago C, Chiavacci L, et al. Q fever seroprevalence and risk factors in sheep and goats in northwest Italy. Prev Vet Med. 2016;130:10-7 pubmed publisher
    Q fever is a zoonosis caused by the bacterium Coxiella burnetii; domestic ruminants, mainly goats and sheep, are the main source of Q fever outbreaks in humans...
  22. Bontje D, Backer J, Hogerwerf L, Roest H, van Roermund H. Analysis of Q fever in Dutch dairy goat herds and assessment of control measures by means of a transmission model. Prev Vet Med. 2016;123:71-89 pubmed publisher
    ..analyze Q fever dynamics in goat herds and to study the effect of control measures, a within-herd model of Coxiella burnetii transmission in dairy goat herds was developed...
  23. Chaligiannis Ι, Fernandez de Mera I, Papa A, Sotiraki S, De La Fuente J. Molecular identification of tick-borne pathogens in ticks collected from dogs and small ruminants from Greece. Exp Appl Acarol. 2018;74:443-453 pubmed publisher
    ..l. and one R. bursa. All ticks were tested for the presence of DNA of Anaplasma spp., Babesia spp., Coxiella burnetii, Rickettsia spp. and Theileria spp...
  24. Lehner S, Lohan K, Dieckhoff H, Gerdes U. [Effects of vaccination against Q-fever in Lower Saxony dairy cattle farms]. Tierarztl Prax Ausg G Grosstiere Nutztiere. 2017;45:141-149 pubmed publisher
    ..Material und methods: All farmers, on whose farms clinical signs of Q-fever and the pathogen Coxiella burnetii had been detected prior to vaccination and who had taken advantage of the hardship allowance during the ..
  25. Osimani A, Milanovic V, Garofalo C, Cardinali F, Roncolini A, Sabbatini R, et al. Revealing the microbiota of marketed edible insects through PCR-DGGE, metagenomic sequencing and real-time PCR. Int J Food Microbiol. 2018;276:54-62 pubmed publisher
    ..Real-time PCR allowed for ascertainment of the absence of Coxiella burnetii, Shiga toxin-producing E. coli (STEC), and Pseudomonas aeruginosa in all samples...
  26. Antunes S, Ferrolho J, Domingues N, Santos A, Santos Silva M, Domingos A. Anaplasma marginale and Theileria annulata in questing ticks from Portugal. Exp Appl Acarol. 2016;70:79-88 pubmed publisher
    ..b>Coxiella burnetii and Theileria spp...
  27. Santoro M, Veneziano V, D Alessio N, Di Prisco F, Lucibelli M, Borriello G, et al. Molecular survey of Ehrlichia canis and Coxiella burnetii infections in wild mammals of southern Italy. Parasitol Res. 2016;115:4427-4431 pubmed
    Ehrlichiosis and Q fever caused by the intracellular bacteria Ehrlichia canis and Coxiella burnetii, respectively, are tick-borne diseases with zoonotic potential and widespread geographical distribution...
  28. Cipolla D, Blanchard J, Gonda I. Development of Liposomal Ciprofloxacin to Treat Lung Infections. Pharmaceutics. 2016;8: pubmed publisher
    ..infections or potential inhaled biowarfare agents including Francisella tularensis, Yersinia pestis and Coxiella burnetii (which cause pneumonic tularemia, plague and Q fever, respectively)...
  29. Prudent E, Lepidi H, Angelakis E, Raoult D. Fluorescence In Situ Hybridization (FISH) and Peptide Nucleic Acid Probe-Based FISH for Diagnosis of Q Fever Endocarditis and Vascular Infections. J Clin Microbiol. 2018;56: pubmed publisher
    Endocarditis and vascular infections are common manifestations of persistent localized infection due to Coxiella burnetii, and recently, fluorescence in situ hybridization (FISH) was proposed as an alternative tool for ..
  30. Politi F, Figueira G, Araujo A, Sampieri B, Mathias M, Szabó M, et al. Acaricidal activity of ethanolic extract from aerial parts of Tagetes patula L. (Asteraceae) against larvae and engorged adult females of Rhipicephalus sanguineus (Latreille, 1806). Parasit Vectors. 2012;5:295 pubmed publisher
    ..and is proven to be involved in the transmission of pathogens such as Babesia canis, Ehrlichia canis, Coxiella burnetii, Rickettsia ricketsii, Rickettsia conorii, among others...
  31. Garcia E, Espeso G, Fernandez R, Gómez Martín A, Rodríguez Linde J, de la Fe C. Coxiella burnetii detected in three species of endangered North African gazelles that recently aborted. Theriogenology. 2017;88:131-133 pubmed publisher
    ..The consequences of the findings are discussed here, showing the need to adopt urgent control measures to prevent the spread of C. burnetii in captive populations that are essential for the conservation of these endangered species. ..
  32. Mares Guia M, Guterres A, Rozental T, Ferreira M, Lemos E. Clinical and epidemiological use of nested PCR targeting the repetitive element IS1111 associated with the transposase gene from Coxiella burnetii. Braz J Microbiol. 2018;49:138-143 pubmed publisher
    Q fever is a worldwide zoonosis caused by Coxiella burnetii-a small obligate intracellular Gram-negative bacterium found in a variety of animals...
  33. Miller H, Binder A, Peterson A, Theel E, Volpe J, Couturier M, et al. Trends in Q fever serologic testing by immunofluorescence from four large reference laboratories in the United States, 2012-2016. Sci Rep. 2018;8:16670 pubmed publisher
    Laboratory testing for Q fever (Coxiella burnetii) is essential for a differential diagnosis, yet little is known about Q fever diagnostic testing practices in the United States...
  34. Bisle S, Klingenbeck L, Borges V, Sobotta K, Schulze Luehrmann J, Menge C, et al. The inhibition of the apoptosis pathway by the Coxiella burnetii effector protein CaeA requires the EK repetition motif, but is independent of survivin. Virulence. 2016;7:400-12 pubmed publisher
    ABSRTACT Coxiella burnetii is an obligate intracellular bacterium that causes Query (Q) fever, a zoonotic disease...
  35. Joulié A, Laroucau K, Bailly X, Prigent M, Gasqui P, Lepetitcolin E, et al. Circulation of Coxiella burnetii in a Naturally Infected Flock of Dairy Sheep: Shedding Dynamics, Environmental Contamination, and Genotype Diversity. Appl Environ Microbiol. 2015;81:7253-60 pubmed publisher
    Q fever is a worldwide zoonosis caused by Coxiella burnetii. Domestic ruminants are considered to be the main reservoir. Sheep, in particular, may frequently cause outbreaks in humans...
  36. Orynbayev M, Beauvais W, Sansyzbay A, Rystaeva R, Sultankulova K, Kerimbaev A, et al. Seroprevalence of infectious diseases in saiga antelope (Saiga tatarica tatarica) in Kazakhstan 2012-2014. Prev Vet Med. 2016;127:100-4 pubmed publisher
    ..virus, Schmallenberg virus, Chlamydophila, Toxoplasma, Mycobacterium avium subspecies paratuberculosis and Coxiella burnetii (Q Fever)...
  37. Angelakis E, Mediannikov O, Socolovschi C, Mouffok N, Bassene H, Tall A, et al. Coxiella burnetii-positive PCR in febrile patients in rural and urban Africa. Int J Infect Dis. 2014;28:107-10 pubmed publisher
    ..The objective of this study was to detect the presence of Coxiella burnetii in febrile patients from Africa...
  38. Soltysiak K, van Schaik E, Samuel J. Surfactant Protein D Binds to Coxiella burnetii and Results in a Decrease in Interactions with Murine Alveolar Macrophages. PLoS ONE. 2015;10:e0136699 pubmed publisher
    b>Coxiella burnetii is a Gram-negative, obligate intracellular bacterium and the causative agent of Q fever. Infections are usually acquired after inhalation of contaminated particles, where C...
  39. González Barrio D, Martín Hernando M, Ruiz Fons F. Shedding patterns of endemic Eurasian wild boar (Sus scrofa) pathogens. Res Vet Sci. 2015;102:206-11 pubmed publisher
    ..We investigated shedding routes of ADV, porcine parvovirus (PPV), porcine circovirus type 2 (PCV2) and Coxiella burnetii and analysed the effect of host sex and age on pathogen shedding patterns...
  40. Halajian A, Palomar A, Portillo A, Heyne H, Luus Powell W, Oteo J. Investigation of Rickettsia, Coxiella burnetii and Bartonella in ticks from animals in South Africa. Ticks Tick Borne Dis. 2016;7:361-6 pubmed publisher
    ..b>Coxiella burnetii and Bartonella spp. Human diseases caused by these microorganisms have been reported from South Africa...
  41. Piñero A, Barandika J, García Pérez A, Hurtado A. Genetic diversity and variation over time of Coxiella burnetii genotypes in dairy cattle and the farm environment. Infect Genet Evol. 2015;31:231-5 pubmed publisher
    The genetic diversity of Coxiella burnetii from 36 dairy cattle herds was determined by Multiple-Locus Variable number tandem repeats Analysis (MLVA), and genotypes from different sources (bulk-tank milk - BTM and surface dust) and ..
  42. Labra Ã, Arredondo Zelada O, Flores Herrera P, Marshall S, Gómez F. In sílico identification and characterization of putative Dot/Icm secreted virulence effectors in the fish pathogen Piscirickettsia salmonis. Microb Pathog. 2016;92:11-18 pubmed publisher
    ..The bacterium is phylogenetically related to Legionella pneumophila and Coxiella burnetii, sharing a Dot/Icm secretion system with them. Although it is well documented that L. pneumophila and C...
  43. Lührmann A, Newton H, Bonazzi M. Beginning to Understand the Role of the Type IV Secretion System Effector Proteins in Coxiella burnetii Pathogenesis. Curr Top Microbiol Immunol. 2017;413:243-268 pubmed publisher
    b>Coxiella burnetii is the etiological agent of the zoonotic disease Q fever, which manifests in severe outbreaks and is associated with important health and economic burden. Moreover, C...
  44. Di Domenico M, Curini V, Di Lollo V, Massimini M, Di Gialleonardo L, Franco A, et al. Genetic diversity of Coxiella burnetii in domestic ruminants in central Italy. BMC Vet Res. 2018;14:171 pubmed publisher
    As the epidemiology of human Q Fever generally reflects the spread of Coxiella burnetii in ruminant livestock, molecular characterization of strains is essential to prevent human outbreaks...
  45. Meadows S, Jones Bitton A, McEwen S, Jansen J, Menzies P. Coxiella burnetii seropositivity and associated risk factors in sheep in Ontario, Canada. Prev Vet Med. 2015;122:129-34 pubmed publisher
    b>Coxiella burnetii is a zoonotic bacterium that can cause abortion in sheep in late gestation, as well as the delivery of stillborn, and non-viable lambs (Rodolakis, 2006)...
  46. Psaroulaki A, Chochlakis D, Ioannou I, Angelakis E, Tselentis Y. Presence of Coxiella burnetii in fleas in Cyprus. Vector Borne Zoonotic Dis. 2014;14:685-7 pubmed publisher
    Over 40 tick species are naturally infected by Coxiella burnetii. However, little is known about the presence of C. burnetii in other ectoparasites such as fleas...
  47. D Amato F, Robert C, Azhar E, Fournier P, Raoult D. Draft Genome Sequence of Coxiella burnetii Strain Cb196, an Agent of Endocarditis in Saudi Arabia. Genome Announc. 2014;2: pubmed publisher
    b>Coxiella burnetii Cb196, with a 2,006,415-bp genome, is a strain isolated from a 45-year-old man in Saudi Arabia with endocarditis. It belongs to the genotype MST51, which was detected for the first time only in this country...
  48. Lagier J, Edouard S, Pagnier I, Mediannikov O, Drancourt M, Raoult D. Current and past strategies for bacterial culture in clinical microbiology. Clin Microbiol Rev. 2015;28:208-36 pubmed publisher
    ..The design of axenic media for growing fastidious bacteria such as Tropheryma whipplei and Coxiella burnetii and the ability of amoebal coculture to discover new bacteria constituted major advances...
  49. Serrano Pérez B, Almería S, Tutusaus J, Jado I, Anda P, Monleón E, et al. Coxiella burnetii total immunoglobulin G, phase I and phase II immunoglobulin G antibodies, and bacterial shedding in young dams in persistently infected dairy herds. J Vet Diagn Invest. 2015;27:167-76 pubmed publisher
    The current study examines Coxiella burnetii infection patterns in young dairy dams around the calving period in persistently infected high-producing dairy herds...
  50. Abu Rmeileh A, Khoury T, Meir K, Drori A, Shalit M, Benenson S, et al. Familial Q fever clustering with variable manifestations imitating infectious and autoimmune disease. Clin Microbiol Infect. 2015;21:459-63 pubmed publisher
    Q fever, caused by Coxiella burnetii, can present as an outbreak of acute disease ranging from asymptomatic disease, pneumonia, hepatitis or fever of unknown origin, which can progress to a chronic disease, most frequently endocarditis...
  51. Ramstead A, Robison A, Blackwell A, Jerome M, Freedman B, Lubick K, et al. Roles of Toll-Like Receptor 2 (TLR2), TLR4, and MyD88 during Pulmonary Coxiella burnetii Infection. Infect Immun. 2016;84:940-949 pubmed publisher
    b>Coxiella burnetii, the causative agent of Q fever, is an obligate intracellular, primarily pulmonary, bacterial pathogen...
  52. Liu J, Ji Y, Shi Z, Jiao Y. [Purification of the recombinant Com1 and adaA of Coxiella burnetii and identification of the antigenicity]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2017;33:726-730 pubmed
    Objective To express and purify two kinds of antigens of Coxiella burnetii (C...
  53. Papakonstantinou P, Samonis G, Andrianaki A, Christofaki M, Dimopoulou D, Papadakis J, et al. Epidemiology, Microbiological and Clinical Features, Treatment, and Outcomes of Infective Endocarditis in Crete, Greece. Infect Chemother. 2018;50:21-28 pubmed publisher
    ..5%) and Streptococcus pneumoniae in one (1%). One patient was serologically positive for Coxiella burnetii (1%)...
  54. Zhang L, Cui F, Wang L, Zhang L, Zhang J, Wang S, et al. Investigation of anaplasmosis in Yiyuan County, Shandong Province, China. Asian Pac J Trop Med. 2011;4:568-72 pubmed publisher
    ..The seroprevalence of Rickettsia typhi was 22.9%, Orientia tsutsugamushi 6.3%, Rickettsia sibirica 27.1%, Coxiella burnetii 18.8%, Bartonella henselae 31.3%, and Borrelia burgdorferi 41.6%...
  55. Elsa J, Duron O, Séverine B, González Acuña D, Sidi Boumedine K. Molecular methods routinely used to detect Coxiella burnetii in ticks cross-react with Coxiella-like bacteria. Infect Ecol Epidemiol. 2015;5:29230 pubmed publisher
    Q fever is a widespread zoonotic disease caused by Coxiella burnetii. Ticks may act as vectors, and many epidemiological studies aim to assess C. burnetii prevalence in ticks...
  56. Nikoh N, Tsuchida T, Maeda T, Yamaguchi K, Shigenobu S, Koga R, et al. Genomic Insight into Symbiosis-Induced Insect Color Change by a Facultative Bacterial Endosymbiont, "Candidatus Rickettsiella viridis". MBio. 2018;9: pubmed publisher
    ..6 Mb) but was smaller than the genomes of phylogenetically allied human pathogens Coxiella burnetii (2.0 Mb) and Legionella pneumophila (3.4 Mb)...
  57. Rahal M, Tahir D, Eldin C, Bitam I, Raoult D, Parola P. Genotyping of Coxiella burnetii detected in placental tissues from aborted dairy cattle in the north of Algeria. Comp Immunol Microbiol Infect Dis. 2018;57:50-54 pubmed publisher
    b>Coxiella burnetii, is an obligate intracellular bacterium which is present throughout the world. In humans, C. burnetii is the causative agent of Q fever...
  58. González Quijada S, Pérez González L, Del Álamo Martínez de Lagos M. Non-diagnostic anti-C. burnetii phase I IgG titres: Should they be discarded in elderly patients?. J Infect Public Health. 2018;11:851-855 pubmed publisher
    High anti-Coxiella burnetii phase I IgG titres are associated with chronic Q fever; an infectious disease with high mortality. Prognostic significance of lower or medium IgG phase I titres remain uncertain...
  59. El Kholy A, El Rachidi N, El Enany M, AbdulRahman E, Mohamed R, Rizk H. Impact of serology and molecular methods on improving the microbiologic diagnosis of infective endocarditis in Egypt. Infection. 2015;43:523-9 pubmed publisher
    ..three sets of blood culture were withdrawn and serum sample was collected for Brucella, Bartonella and Coxiella burnetii antibody testing. Galactomannan antigen was added if fungal endocarditis was suspected...
  60. Dal Pozzo F, Renaville B, Martinelle L, Renaville R, Thys C, Smeets F, et al. Single Nucleotide Polymorphism Genotyping and Distribution of Coxiella burnetii Strains from Field Samples in Belgium. Appl Environ Microbiol. 2016;82:81-6 pubmed publisher
    The genotypic characterization of Coxiella burnetii provides useful information about the strains circulating at the farm, region, or country level and may be used to identify the source of infection for animals and humans...
  61. Cillóniz C, Torres A, Niederman M, van der Eerden M, Chalmers J, Welte T, et al. Community-acquired pneumonia related to intracellular pathogens. Intensive Care Med. 2016;42:1374-86 pubmed publisher
    ..are Legionella pneumophila, Mycoplasma pneumoniae, Chlamydophila pneumoniae, Chlamydophila psittaci, and Coxiella burnetii. Since it is known that antibiotic treatment for severe CAP is empiric and includes coverage of typical and ..
  62. van Roeden S, Melenotte C, Hermans M, Sinnige H, Nooijen P, Audoly G, et al. Case report: Coxiella burnetii vascular infection and lymphoma in the Netherlands. Infection. 2018;46:131-134 pubmed publisher
    Non-Hodgkin lymphoma has been linked to infection with Coxiella burnetii, potentially through overproduction of IL-10 during infection with C. burnetii. Description of a case report...
  63. Chauhan R, Wadhwa G, Sharma S, Jain C. Current developments in therapeutic and diagnostic strategies for Q fever: glimpses of patent analysis. Recent Pat Antiinfect Drug Discov. 2014;9:104-11 pubmed
    b>Coxiella burnetii is an infectious and etiological agent responsible for causing Q fever. There are mainly two forms of the Q fever that are chronic and acute...
  64. D Amato F, Eldin C, Raoult D. The contribution of genomics to the study of Q fever. Future Microbiol. 2016;11:253-72 pubmed publisher
    b>Coxiella burnetii is the etiological agent of Q fever, a worldwide zoonosis that can result in large outbreaks. The birth of genomics and sequencing of C. burnetii strains has revolutionized many fields of study of this infection...
  65. Bessas A, Leulmi H, Bitam I, Zaidi S, Ait Oudhia K, Raoult D, et al. Molecular evidence of vector-borne pathogens in dogs and cats and their ectoparasites in Algiers, Algeria. Comp Immunol Microbiol Infect Dis. 2016;45:23-8 pubmed publisher
    ..18/117 (15.38%) dogs and 2/107 (1.87%) cats were positive for at least one vector-borne agent. Coxiella burnetii and Bartonella henselae were identified in 1/117 (0.85%) dog individually...
  66. Rebbig A, Matthiesen S, Lührmann A, Knittler M. Flow cytometry as a new complementary tool to study Coxiella burnetii in cell cultures. J Microbiol Methods. 2018;151:39-43 pubmed publisher
    ..burnetii-infected cells. The method quantifies infection-forming units (IFUs) in a dose-dependent manner and allows for the specific detection of infection/replication-competent coxiella in cell cultures. ..
  67. Carbonero A, Guzmán L, Montaño K, Torralbo A, Arenas Montés A, Saa L. Coxiella burnetii seroprevalence and associated risk factors in dairy and mixed cattle farms from Ecuador. Prev Vet Med. 2015;118:427-35 pubmed publisher
    Q fever is a zoonotic disease caused by Coxiella burnetii, a bacterial agent for which ruminants are the main reservoir...
  68. Fenga C, Gangemi S, De Luca A, Calimeri S, Lo Giudice D, Pugliese M, et al. Seroprevalence and occupational risk survey for Coxiella burnetii among exposed workers in Sicily, Southern Italy. Int J Occup Med Environ Health. 2015;28:901-7 pubmed publisher
    The aim of this survey was to assess the seroprevalence of antibodies against Coxiella burnetii (C. burnetii) in subjects at risk of exposure in Sicily, Southern Italy. Prevalence of IgG antibodies to C...
  69. Ceglie L, Guerrini E, Rampazzo E, Barberio A, Tilburg J, Hagen F, et al. Molecular characterization by MLVA of Coxiella burnetii strains infecting dairy cows and goats of north-eastern Italy. Microbes Infect. 2015;17:776-81 pubmed publisher
    Q fever is a worldwide zoonotic disease caused by Coxiella burnetii (C. burnetii), an obligate intracellular bacterium...
  70. Khalili M, Reza Naderi H, Salehnia N, Abiri Z. Detection of Coxiella burnetii in acute undifferentiated febrile illnesses (AUFIs) in Iran. Trop Doct. 2016;46:221-224 pubmed
    ..There are limited data on the aetiology of acute undifferentiated febrile illnesses (AUFIs) in Iran. Moreover, Coxiella burnetii has not previously been detected in clinical samples in this country...
  71. Rocchigiani G, Ebani V, Nardoni S, Bertelloni F, Bascherini A, Leoni A, et al. Molecular survey on the occurrence of arthropod-borne pathogens in wild brown hares (Lepus europaeus) from Central Italy. Infect Genet Evol. 2018;59:142-147 pubmed publisher
    ..Borrelia burgdorferi sensu lato, Coxiella burnetii, Francisella tularensis, Leishmania spp...
  72. D Amato F, Rouli L, Edouard S, Tyczka J, Million M, Robert C, et al. The genome of Coxiella burnetii Z3055, a clone linked to the Netherlands Q fever outbreaks, provides evidence for the role of drift in the emergence of epidemic clones. Comp Immunol Microbiol Infect Dis. 2014;37:281-8 pubmed publisher
    b>Coxiella burnetii is a pathogen causing Q fever. The aim of our work was to study Z3055, a strain that is genotypically related to the strain causing the Netherlands outbreak...
  73. Walter M, Vincent G, Stenos J, Graves S, Frangoulidis D. Genome Sequence of Coxiella burnetii Strain AuQ01 (Arandale) from an Australian Patient with Acute Q Fever. Genome Announc. 2014;2: pubmed publisher
    b>Coxiella burnetii strain AuQ01 was isolated from the serum of an Australian acute Q fever patient and represents the first whole genome from this historical Q fever country...
  74. Ciliberti A, Gavier Widén D, Yon L, Hutchings M, Artois M. Prioritisation of wildlife pathogens to be targeted in European surveillance programmes: Expert-based risk analysis focus on ruminants. Prev Vet Med. 2015;118:271-84 pubmed publisher
    ..The resulting top-list pathogens were ranked as follows: 1. Salmonella enterica, 2. Coxiella burnetii, 3. foot-and-mouth disease virus, 4. Mycobacterium bovis, 5. bluetongue virus, and 6...
  75. Sobotta K, Hillarius K, Mager M, Kerner K, Heydel C, Menge C. Coxiella burnetii Infects Primary Bovine Macrophages and Limits Their Host Cell Response. Infect Immun. 2016;84:1722-1734 pubmed publisher
    ..human Q fever, little is known about the lifestyle that the obligate intracellular Gram-negative bacterium Coxiella burnetii adopts in its animal host...
  76. Angelakis E, Khalil J, Le Bideau M, Perreal C, La Scola B, Raoult D. Hydroxychloroquine susceptibility determination of Coxiella burnetii in human embryonic lung (HEL) fibroblast cells. Int J Antimicrob Agents. 2017;50:106-109 pubmed publisher
    b>Coxiella burnetii, the causative agent of Q fever, survives and replicates in the acidic environment of monocytes/macrophages; hydroxychloroquine, through alkalinisation of the acidic vacuoles, is critical for the management of Q fever...
  77. Kaufman E, Stone N, Scoles G, Hepp C, Busch J, Wagner D. Range-wide genetic analysis of Dermacentor variabilis and its Francisella-like endosymbionts demonstrates phylogeographic concordance between both taxa. Parasit Vectors. 2018;11:306 pubmed publisher
    ..and Coxiella burnetii), using species-specific quantitative PCR assays...
  78. Sidi Boumedine K, Adam G, Angen Ã, Aspán A, Bossers A, Roest H, et al. Whole genome PCR scanning (WGPS) of Coxiella burnetii strains from ruminants. Microbes Infect. 2015;17:772-5 pubmed publisher
    b>Coxiella burnetii is the causative agent of Q fever, a zoonosis that spreads from ruminants to humans via the inhalation of aerosols contaminated by livestock's birth products...
  79. Dubourg G, Lagier J, Robert C, Armstrong N, Couderc C, Fournier P, et al. Risungbinella massiliensis sp. nov., a new member of Thermoactinomycetaceae isolated from human gut. Antonie Van Leeuwenhoek. 2016;109:773-84 pubmed publisher
    ..bacterium, designated GD1(T), was isolated from the gut microbiota of a 38-year-old male who suffered from a Coxiella burnetii vascular for which he received multiple a broad-spectrum antibiotic cocktail at the time of the stool ..
  80. Raeven V, Spoorenberg S, Boersma W, van de Garde E, Cannegieter S, Voorn G, et al. Atypical aetiology in patients hospitalised with community-acquired pneumonia is associated with age, gender and season; a data-analysis on four Dutch cohorts. BMC Infect Dis. 2016;16:299 pubmed publisher
    ..community-acquired pneumonia (CAP) can be categorised into viral, typical and atypical (Legionella species, Coxiella burnetii, Mycoplasma pneumoniae, and Chlamydia species)...
  81. Walraph J, Zoche Golob V, Weber J, Freick M. Decline of antibody response in indirect ELISA tests during the periparturient period caused diagnostic gaps in Coxiella burnetii and BVDV serology in pluriparous cows within a Holstein dairy herd. Res Vet Sci. 2018;118:91-96 pubmed publisher
    ..burnetii indirect ELISA and until week 11 in the anti-BVDV indirect ELISA, respectively. In conclusion, blood serological investigations in periparturient dairy cows using indirect ELISA kits should be avoided. ..
  82. Sting R, Molz K, Hoferer M. Creating standards for absolute quantification of Coxiella burnetii in real-time PCR--a comparative study based on transmission electron microscopy. Biologicals. 2015;43:18-22 pubmed publisher
    ..In this study the creation of quantitative standards for use in qPCR is described using the pathogen Coxiella burnetii. Quantification of Coxiella burnetii particles by transmission electron microscopy (TEM) was used as primary ..
  83. Graham J, Winchell C, Sharma U, Voth D. Identification of ElpA, a Coxiella burnetii pathotype-specific Dot/Icm type IV secretion system substrate. Infect Immun. 2015;83:1190-8 pubmed publisher
    b>Coxiella burnetii causes human Q fever, a zoonotic disease that presents with acute flu-like symptoms and can result in chronic life-threatening endocarditis. In human alveolar macrophages, C...
  84. Duron O. The IS1111 insertion sequence used for detection of Coxiella burnetii is widespread in Coxiella-like endosymbionts of ticks. FEMS Microbiol Lett. 2015;362:fnv132 pubmed publisher
    ..The type species, Coxiella burnetii, infects several vertebrate species, including humans, and is the causative agent of Q fever...
  85. Minichová L, Hamšíková Z, Mahríková L, Slovak M, Kocianova E, Kazimirova M, et al. Molecular evidence of Rickettsia spp. in ixodid ticks and rodents in suburban, natural and rural habitats in Slovakia. Parasit Vectors. 2017;10:158 pubmed publisher
    ..arvalis, Microtus subterraneus and Micromys minutus) were examined for the presence of SFG rickettsiae and Coxiella burnetii by molecular methods...
  86. Lee S, Heo J, Lee H, Lee Y, Jeong H, Hwang S. Clinical and Genetic Features of Coxiella burnetii in a Patient with an Acute Febrile Illness in Korea. J Korean Med Sci. 2017;32:1038-1041 pubmed publisher
    Although Q fever is an important zoonotic infection with a worldwide distribution, no human isolates of Coxiella burnetii have been identified in Korea. For the first time, we identified the nucleotide sequence of C...
  87. Peng Y, Schoenlaub L, Elliott A, Mitchell W, Zhang G. Characterization of a lipopolysaccharide-targeted monoclonal antibody and its variable fragments as candidates for prophylaxis against the obligate intracellular bacterial pathogen Coxiella burnetii. Infect Immun. 2014;82:4530-41 pubmed publisher
    Our previous study demonstrated that treatment of Coxiella burnetii with the phase I lipopolysaccharide (PI-LPS)-targeted monoclonal antibody (MAb) 1E4 significantly inhibited C...
  88. Ammerdorffer A, Schoffelen T, Gresnigt M, Oosting M, den Brok M, Abdollahi Roodsaz S, et al. Recognition of Coxiella burnetii by toll-like receptors and nucleotide-binding oligomerization domain-like receptors. J Infect Dis. 2015;211:978-87 pubmed publisher
    Infection with Coxiella burnetii can lead to acute and chronic Q fever...
  89. Gwida M, El Ashker M, El Diasty M, Engelhardt C, Khan I, Neubauer H. Q fever in cattle in some Egyptian Governorates: a preliminary study. BMC Res Notes. 2014;7:881 pubmed publisher
    Q fever, caused by Coxiella burnetii, is a zoonosis with great public health significance and can cause financial losses to animal owners. The knowledge of the epidemiology of Q fever in Egypt is limited...
  90. Špitalská E, Boldiš V, Mošanský L, Sparagano O, Stanko M. Rickettsia species in fleas collected from small mammals in Slovakia. Parasitol Res. 2015;114:4333-9 pubmed publisher
    ..Hystrichopsyllidae and Leptopsyllidae families were tested for the presence of Rickettsia species and Coxiella burnetii with conventional and specific quantitative real-time PCR assays...
  91. Cicuttin G, Degiuseppe J, Mamianetti A, Corin M, Linares M, De Salvo M, et al. Serological evidence of Rickettsia and Coxiella burnetii in humans of Buenos Aires, Argentina. Comp Immunol Microbiol Infect Dis. 2015;43:57-60 pubmed publisher
    ..our study was to determine the seroprevalence of Rickettsia (spotted fever--SFG--and typhus--TG--groups) and Coxiella burnetii (Q fever agent) in residents of Buenos Aires city. The study involved 99 participants...
  92. Biggs H, Turabelidze G, Pratt D, Todd S, Jacobs Slifka K, Drexler N, et al. Coxiella burnetii Infection in a Community Operating a Large-Scale Cow and Goat Dairy, Missouri, 2013. Am J Trop Med Hyg. 2016;94:525-31 pubmed publisher
    b>Coxiella burnetii is a zoonotic pathogen that causes Q fever in humans and is transmitted primarily from infected goats, sheep, or cows...