fruiting gliding bacteria


Alias: Myxococcales, Myxobacteria, Myxococcales Tchan et al. 1948, The Myxobacteria

Top Publications

  1. Kim B, Minh N, Choi H, Kim W. Coralmycin Derivatives with Potent Anti-Gram Negative Activity Produced by the Myxobacteria Corallococcus coralloides M23. Molecules. 2019;24: pubmed publisher
    ..compounds, cystobactamids 891-2 (8), 905-2 (9), and 507 (10), were isolated from a large-scale culture of the myxobacteria Corallococcus coralloides M23...
  2. Azad E, Derakhshani H, Forster R, Gruninger R, Acharya S, McAllister T, et al. Characterization of the rumen and fecal microbiome in bloated and non-bloated cattle grazing alfalfa pastures and subjected to bloat prevention strategies. Sci Rep. 2019;9:4272 pubmed publisher
    ..Streptococcus, Succinivibrio and unclassified Myxococcales were enriched in the rumen microbiota of bloated steers, whereas Fibrobacter and Ruminococcus were ..
  3. Li Z, Xia C, Wang Y, Li X, Qiao Y, Li C, et al. Identification of an endo-chitinase from Corallococcus sp. EGB and evaluation of its antifungal properties. Int J Biol Macromol. 2019;132:1235-1243 pubmed publisher
    ..EGB. CcCti1 lacks a fibronectin type-III (FN3) domain that is present in similar enzymes from most genera of myxobacteria, indicating that CcCti1 may have acquired chitinase activity due to the FN3 domain deletion during ..
  4. Cao P, Wei X, Awal R, Muller R, Wall D. A Highly Polymorphic Receptor Governs Many Distinct Self-Recognition Types within the Myxococcales Order. MBio. 2019;10: pubmed publisher
    ..Here we describe a single locus, traA, in myxobacteria that governs cell-cell recognition within natural populations...
  5. Welz P, Khan N, Prins A. The effect of biogenic and chemically manufactured silver nanoparticles on the benthic bacterial communities in river sediments. Sci Total Environ. 2018;644:1380-1390 pubmed publisher
    ..abundance) to one or both forms of silver nanoparticles was seen in the class Thermoleophilia, and the orders Myxococcales, Bacteriodales, Pirellules CCU21 and iii 1-15 (class Acidobacteria 6)...
  6. Tong Y, Weber T, Lee S. CRISPR/Cas-based genome engineering in natural product discovery. Nat Prod Rep. 2018;: pubmed publisher
    ..The organisms covered include bacteria such as Streptomyces, Corynebacteria, and Myxobacteria; filamentous fungi such as Aspergillus, Beauveria, and Ganoderma; microalgae; and some plants...
  7. Cui X, Zhang Y, Gao J, Peng F, Gao P. Long-term combined application of manure and chemical fertilizer sustained higher nutrient status and rhizospheric bacterial diversity in reddish paddy soil of Central South China. Sci Rep. 2018;8:16554 pubmed publisher
    ..and Nitrospiraceae, while manure significantly increased the abundances of Deltaproteobacteria and Myxococcales, but the most abundant Actinobacteria and Planctomycetes were detected in the treatment that combined ..
  8. Hug J, Panter F, Krug D, Muller R. Genome mining reveals uncommon alkylpyrones as type III PKS products from myxobacteria. J Ind Microbiol Biotechnol. 2019;46:319-334 pubmed publisher
    ..This gap is exemplified by myxobacteria from which no type III PKS-derived small molecule has previously been isolated...
  9. Chauhan D, Bartok E, Gaidt M, Bock F, Herrmann J, Seeger J, et al. BAX/BAK-Induced Apoptosis Results in Caspase-8-Dependent IL-1β Maturation in Macrophages. Cell Rep. 2018;25:2354-2368.e5 pubmed publisher
    ..Guided by the discovery of the immunomodulatory activity of vioprolides, cyclic peptides isolated from myxobacteria, we observe IL-1β maturation independent of canonical inflammasome pathways, yet dependent on intrinsic ..

More Information


  1. Dehhaghi M, Tan V, Heng B, Mohammadipanah F, Guillemin G. Protective Effects of Myxobacterial Extracts on Hydrogen Peroxide-induced Toxicity on Human Primary Astrocytes. Neuroscience. 2019;399:1-11 pubmed publisher
    ..b>Myxobacteria produce a wide range of bioactive metabolites with notable structures and modes of action, which introduce them ..
  2. Amiri Moghaddam J, Crüsemann M, Alanjary M, Harms H, Dávila Céspedes A, Blom J, et al. Analysis of the Genome and Metabolome of Marine Myxobacteria Reveals High Potential for Biosynthesis of Novel Specialized Metabolites. Sci Rep. 2018;8:16600 pubmed publisher
    ..In the group of marine myxobacteria only a limited number of isolated species and sequenced genomes is so far available...
  3. Dehhaghi M, Tan V, Heng B, Braidy N, Mohammadipanah F, Guillemin G. Neuroprotective Effect of Myxobacterial Extracts on Quinolinic Acid-Induced Toxicity in Primary Human Neurons. Neurotox Res. 2019;35:281-290 pubmed publisher
    ..b>Myxobacteria have been known as a rich source of secondary metabolites with diverse structures and mode of actions...
  4. Sharma G, Parales R, Singer M. In silico characterization of a novel putative aerotaxis chemosensory system in the myxobacterium, Corallococcus coralloides. BMC Genomics. 2018;19:757 pubmed publisher
    ..Overall, this in silico study has identified a potentially innovative and evolved mechanism of energy taxis in only one of the myxobacteria, C. coralloides.
  5. Baumann S, Herrmann J, Raju R, Steinmetz H, Mohr K, Hüttel S, et al. Cystobactamids: myxobacterial topoisomerase inhibitors exhibiting potent antibacterial activity. Angew Chem Int Ed Engl. 2014;53:14605-9 pubmed publisher
    ..Herein, we report highly potent novel antibacterial compounds, the myxobacteria-derived cystobactamids 1-3, which were isolated from Cystobacter sp...
  6. Schulz E, Goes A, Garcia R, Panter F, Koch M, Muller R, et al. Biocompatible bacteria-derived vesicles show inherent antimicrobial activity. J Control Release. 2018;290:46-55 pubmed publisher
    ..We isolated OMVs from two representative strains of myxobacteria, Cystobacter velatus Cbv34 and Sorangiineae species strain SBSr073, a bacterial order with the ability of ..
  7. Korp J, Winand L, Sester A, Nett M. Engineering Pseudochelin Production in Myxococcus xanthus. Appl Environ Microbiol. 2018;84: pubmed publisher
    b>Myxobacteria utilize the catechol natural products myxochelin A and B in order to maintain their iron homeostasis...
  8. Livingstone P, Morphew R, Cookson A, Whitworth D. Genome Analysis, Metabolic Potential, and Predatory Capabilities of Herpetosiphon llansteffanense sp. nov. Appl Environ Microbiol. 2018;84: pubmed publisher
    ..wolf pack predation, yet its members are poorly described compared to other wolf pack predators, such as the myxobacteria. By providing a thorough characterization of a novel Herpetosiphon species, including its predatory, ..
  9. Gemperlein K, Zaburannyi N, Garcia R, La Clair J, Muller R. Metabolic and Biosynthetic Diversity in Marine Myxobacteria. Mar Drugs. 2018;16: pubmed publisher
    Prior to 2005, the vast majority of characterized myxobacteria were obtained from terrestrial habitats. Since then, several species of halotolerant and even obligate marine myxobacteria have been described...
  10. Garcia R, La Clair J, Muller R. Future Directions of Marine Myxobacterial Natural Product Discovery Inferred from Metagenomics. Mar Drugs. 2018;16: pubmed publisher
    ..thrive at high salt concentrations) and halotolerant (organisms that have adapted to high salt concentrations) myxobacteria emerged as an important source of structurally diverse secondary metabolites from the marine environment...
  11. Mohr K. Diversity of Myxobacteria-We Only See the Tip of the Iceberg. Microorganisms. 2018;6: pubmed publisher
    ..Among actinomycetes, Bacillus species, and fungi, myxobacteria have been a rich source for bioactive secondary metabolites for decades...
  12. Santín O, Moncalian G. Loading of malonyl-CoA onto tandem acyl carrier protein domains of polyunsaturated fatty acid synthases. J Biol Chem. 2018;293:12491-12501 pubmed publisher
    ..fatty acids (PUFA) are produced in some unicellular organisms, such as marine gammaproteobacteria, myxobacteria, and thraustochytrids, by large enzyme complexes called PUFA synthases...
  13. Dey A, Wall D. A genetic screen in Myxococcus xanthus identifies mutants that uncouple outer membrane exchange from a downstream cellular response. J Bacteriol. 2014;196:4324-32 pubmed publisher
    Upon physical contact with sibling cells, myxobacteria transiently fuse their outer membranes (OMs) and exchange OM proteins and lipids...
  14. Held J, Gebru T, Kalesse M, Jansen R, Gerth K, Müller R, et al. Antimalarial activity of the myxobacterial macrolide chlorotonil a. Antimicrob Agents Chemother. 2014;58:6378-84 pubmed publisher
    b>Myxobacteria are Gram-negative soil-dwelling bacteria belonging to the phylum Proteobacteria. They are a rich source of promising compounds for clinical application, such as epothilones for cancer therapy and several new antibiotics...
  15. Wang W, Wang H, Feng Y, Wang L, Xiao X, Xi Y, et al. Consistent responses of the microbial community structure to organic farming along the middle and lower reaches of the Yangtze River. Sci Rep. 2016;6:35046 pubmed publisher
    ..guilds and major bacterial lineages (Rhizobiales, Thiotrichaceae, Micromonosporaceae, Desulfurellaceae and Myxococcales) contributing to nutrient (C, N, S and P) cycling were enriched, whereas the relative abundances of acid and ..
  16. Vasse M, Wielgoss S. Bacteriophages of Myxococcus xanthus, a Social Bacterium. Viruses. 2018;10: pubmed publisher
    ..Here, we review knowledge on the phages of the myxobacteria with a major focus on phages infecting Myxococcus xanthus, a bacterial model system widely used to ..
  17. Albataineh H, Stevens D. Marine Myxobacteria: A Few Good Halophiles. Mar Drugs. 2018;16: pubmed publisher
    Currently considered an excellent candidate source of novel chemical diversity, the existence of marine myxobacteria was in question less than 20 years ago...
  18. Panter F, Krug D, Baumann S, Muller R. Self-resistance guided genome mining uncovers new topoisomerase inhibitors from myxobacteria. Chem Sci. 2018;9:4898-4908 pubmed publisher
    ..coli topoisomerase IV and human topoisomerase I by pyxidicyclines as well as precise selectivity, since E. coli topoisomerase II (gyrase) was not inhibited at concentrations up to 50 ?g ml-1. ..
  19. Virga E. Dissipative shocks behind bacteria gliding. Philos Trans A Math Phys Eng Sci. 2014;372: pubmed publisher
    Gliding is a means of locomotion on rigid substrates used by a number of bacteria, including myxobacteria and cyanobacteria...
  20. Mulwa L, Stadler M. Antiviral Compounds from Myxobacteria. Microorganisms. 2018;6: pubmed publisher
    ..b>Myxobacteria are in the focus of this review since they produce numerous structurally and functionally unique bioactive ..
  21. Zhou Z, Qiao W, Xing C, Shen X, Hu D, Wang L. A micro-aerobic hydrolysis process for sludge in situ reduction: performance and microbial community structure. Bioresour Technol. 2014;173:452-456 pubmed publisher
    ..Ramlibacter), fermentative acidogenic bacteria (Propionivibrio; Opitutus; Caldilinea), slow growers (Ramlibacter) and predatory bacteria (Myxobacteria) in SPRAS system. Nitrifiers were also more abundant in SPRAS system than AO system.
  22. Oliveira V, Gomes N, Cleary D, Almeida A, Silva A, Simões M, et al. Halophyte plant colonization as a driver of the composition of bacterial communities in salt marshes chronically exposed to oil hydrocarbons. FEMS Microbiol Ecol. 2014;90:647-62 pubmed publisher
    ..from both plant species revealed enrichment of operational taxonomic units closely related to Acidimicrobiales, Myxococcales and Sphingomonadales...
  23. Crossman L, Chen H, Cerdeño Tárraga A, Brooks K, Quail M, Pineiro S, et al. A small predatory core genome in the divergent marine Bacteriovorax marinus SJ and the terrestrial Bdellovibrio bacteriovorus. ISME J. 2013;7:148-60 pubmed publisher
    ..shared between Bacteriovorax and Bdellovibrio that is not conserved among other delta-proteobacteria such as Myxobacteria (which destroy prey bacteria externally via lysis), or the non-predatory Desulfo-bacteria and Geobacter species ..
  24. Gemperlein K, Zipf G, Bernauer H, Müller R, Wenzel S. Metabolic engineering of Pseudomonas putida for production of docosahexaenoic acid based on a myxobacterial PUFA synthase. Metab Eng. 2016;33:98-108 pubmed publisher
    ..Recently similar gene clusters were detected and characterized in terrestrial myxobacteria revealing several striking differences...
  25. Premnath P, Reck M, Wittstein K, Stadler M, Wagner Dobler I. Screening for inhibitors of mutacin synthesis in Streptococcus mutans using fluorescent reporter strains. BMC Microbiol. 2018;18:24 pubmed publisher
    ..reporter strain 423p - gfp + was used to screen 297 secondary metabolites from different sources, mainly myxobacteria and fungi, for their ability to reduce the fluorescence of the fully induced reporter strain by > 50% ..
  26. Vassallo C, Pathak D, Cao P, Zuckerman D, Hoiczyk E, Wall D. Cell rejuvenation and social behaviors promoted by LPS exchange in myxobacteria. Proc Natl Acad Sci U S A. 2015;112:E2939-46 pubmed publisher
    ..We propose that OME is a mechanism that myxobacteria use to overcome cell damage and to transition to a multicellular organism.
  27. Troselj V, Treuner Lange A, Søgaard Andersen L, Wall D. Physiological Heterogeneity Triggers Sibling Conflict Mediated by the Type VI Secretion System in an Aggregative Multicellular Bacterium. MBio. 2018;9: pubmed publisher
    ..For instance, myxobacteria use an aggregation strategy to form multicellular, spore-filled fruiting bodies in response to starvation...
  28. Wenzel S, Hoffmann H, Zhang J, Debussche L, Haag Richter S, Kurz M, et al. Production of the Bengamide Class of Marine Natural Products in Myxobacteria: Biosynthesis and Structure-Activity Relationships. Angew Chem Int Ed Engl. 2015;54:15560-4 pubmed publisher
  29. Li B, Yao Q, Zhu H. Approach to analyze the diversity of myxobacteria in soil by semi-nested PCR-denaturing gradient gel electrophoresis (DGGE) based on taxon-specific gene. PLoS ONE. 2014;9:e108877 pubmed publisher
    ..Furthermore, sequencing and BLAST revealed that most of the bands belonged to the myxobacteria-group, and only three of the twenty-eight bands belonged to other group, i.e., Deinococcus maricopensis...
  30. de Almeida Fernandes L, Pereira A, Leal C, Davenport R, Werner D, Filho C, et al. Effect of temperature on microbial diversity and nitrogen removal performance of an anammox reactor treating anaerobically pretreated municipal wastewater. Bioresour Technol. 2018;258:208-219 pubmed publisher
    ..Anammox bacteria (Ca. Brocadia and Ca. Anammoximicrobium) and denitrifiers (Burkholderiales, Myxococcales, Rhodocyclales, Xanthomonadales, and Pseudomonadales) were favoured when the temperature was lowered from 35?°..
  31. Seccareccia I, Kost C, Nett M. Quantitative Analysis of Lysobacter Predation. Appl Environ Microbiol. 2015;81:7098-105 pubmed publisher
    ..the genus Lysobacter are considered to be facultative predators that use a feeding strategy similar to that of myxobacteria. Experimental data supporting this assumption, however, are scarce...
  32. Krastel P, Roggo S, Schirle M, Ross N, Perruccio F, Aspesi P, et al. Nannocystin A: an Elongation Factor 1 Inhibitor from Myxobacteria with Differential Anti-Cancer Properties. Angew Chem Int Ed Engl. 2015;54:10149-54 pubmed publisher
    Cultivation of myxobacteria of the Nannocystis genus led to the isolation and structure elucidation of a class of novel cyclic lactone inhibitors of elongation factor 1...
  33. Cao P, Dey A, Vassallo C, Wall D. How Myxobacteria Cooperate. J Mol Biol. 2015;427:3709-21 pubmed publisher
    ..A notable exception is the myxobacteria, in which cells cooperate to perform group functions highlighted by fruiting body development, an obligate ..
  34. Whitworth D. Genome-wide analysis of myxobacterial two-component systems: genome relatedness and evolutionary changes. BMC Genomics. 2015;16:780 pubmed publisher
    ..relationship between evolutionary distance and the inference of TCS estudies of TCS evolution beyond the myxobacteriavolution, which may be important for studies of TCS evolutiThe online version of this articleon beyond the myxobacteria.
  35. Sun Y, Tomura T, Sato J, Iizuka T, Fudou R, Ojika M. Isolation and Biosynthetic Analysis of Haliamide, a New PKS-NRPS Hybrid Metabolite from the Marine Myxobacterium Haliangium ochraceum. Molecules. 2016;21:59 pubmed publisher
    b>Myxobacteria of marine origin are rare and hard-to-culture microorganisms, but they genetically harbor high potential to produce novel antibiotics...
  36. Castro C, Freitag J, Berod L, Lochner M, Sparwasser T. Microbe-associated immunomodulatory metabolites: Influence on T cell fate and function. Mol Immunol. 2015;68:575-84 pubmed publisher
    ..The second, soraphen A (isolated from Myxobacteria), was discovered in the early 1990s but only recently identified as a promising immunomodulator...
  37. Hoffmann T, Krug D, Bozkurt N, Duddela S, Jansen R, Garcia R, et al. Correlating chemical diversity with taxonomic distance for discovery of natural products in myxobacteria. Nat Commun. 2018;9:803 pubmed publisher
    ..Here we perform a systematic metabolite survey of ~2300 bacterial strains of the order Myxococcales, a well-established source of natural products, using mass spectrometry...
  38. Gölz J, Bockelmann S, Mayer K, Steinhoff H, Wieczorek H, Huss M, et al. EPR Studies of V-ATPase with Spin-Labeled Inhibitors DCC and Archazolid: Interaction Dynamics with Proton Translocating Subunit c. ChemMedChem. 2016;11:420-8 pubmed publisher
    ..noncovalent interaction of a radical analogue of the highly potent inhibitor archazolid, a natural product from myxobacteria. Both complexes were evaluated in detail by electron paramagnetic resonance (EPR) spectroscopic studies and ..
  39. Dehhaghi M, Mohammadipanah F, Guillemin G. Myxobacterial natural products: An under-valued source of products for drug discovery for neurological disorders. Neurotoxicology. 2018;66:195-203 pubmed publisher
    ..b>Myxobacteria, a group of Gram-negative bacteria with large genome size, produce a wide range of secondary metabolites with ..
  40. Ahrendt T, Wolff H, Bode H. Neutral and Phospholipids of the Myxococcus xanthus Lipodome during Fruiting Body Formation and Germination. Appl Environ Microbiol. 2015;81:6538-47 pubmed publisher
    b>Myxobacteria are well-known for their complex life cycle, including the formation of spore-filled fruiting bodies...
  41. Herrmann J, Fayad A, Muller R. Natural products from myxobacteria: novel metabolites and bioactivities. Nat Prod Rep. 2017;34:135-160 pubmed publisher
    ..Here we report on new natural products that were isolated from myxobacteria in the period of 2011 to July 2016...
  42. Osborn A, Kean K, Alseud K, Almabruk K, Asamizu S, Lee J, et al. Evolution and Distribution of C7-Cyclitol Synthases in Prokaryotes and Eukaryotes. ACS Chem Biol. 2017;12:979-988 pubmed publisher various prokaryotes and eukaryotes, including pathogenic bacteria, plant symbionts, nitrogen-fixing bacteria, myxobacteria, cyanobacteria, fungi, stramenopiles, and animals, suggesting their broad potential biological roles in nature.
  43. Reimer L, Söhngen C, Vetcininova A, Overmann J. Mobilization and integration of bacterial phenotypic data-Enabling next generation biodiversity analysis through the BacDive metadatabase. J Biotechnol. 2017;261:187-193 pubmed publisher
    ..The Reichenbach collection of myxobacteria includes information on 12,535 typewritten index cards which were digitized...
  44. Gallego García A, Iniesta A, Gonzalez D, Collier J, Padmanabhan S, Elías Arnanz M. Caulobacter crescentus CdnL is a non-essential RNA polymerase-binding protein whose depletion impairs normal growth and rRNA transcription. Sci Rep. 2017;7:43240 pubmed publisher
    CdnL is an essential RNA polymerase (RNAP)-binding activator of rRNA transcription in mycobacteria and myxobacteria but reportedly not in Bacillus...
  45. Peng R, Wang Y, Feng W, Yue X, Chen J, Hu X, et al. CRISPR/dCas9-mediated transcriptional improvement of the biosynthetic gene cluster for the epothilone production in Myxococcus xanthus. Microb Cell Fact. 2018;17:15 pubmed publisher
    ..This is the first time to construct the CRISPR/dCas9 activation system in myxobacteria and the first time to assay the CRISPR/dCas9 activations for the biosynthesis of microbial secondary ..
  46. Nan B, Zusman D. Novel mechanisms power bacterial gliding motility. Mol Microbiol. 2016;101:186-93 pubmed publisher
    ..In this review, we summarize recent findings made on the gliding mechanisms of the myxobacteria, flavobacteria and mycoplasmas.
  47. Dey A, Vassallo C, Conklin A, Pathak D, Troselj V, Wall D. Sibling Rivalry in Myxococcus xanthus Is Mediated by Kin Recognition and a Polyploid Prophage. J Bacteriol. 2016;198:994-1004 pubmed publisher
    b>Myxobacteria form complex social communities that elicit multicellular behaviors...
  48. Zhang Y, Liu R, Liu B. Total synthesis of nannocystin Ax. Chem Commun (Camb). 2017;53:5549-5552 pubmed publisher
    A concise total synthesis of nannocystin Ax, a natural depsipeptide recently isolated from myxobacteria, has been accomplished. By following a convergent strategy, the target molecule was assembled from three fragments...
  49. Yu Y, Kleiner M, Velicer G. Spontaneous Reversions of an Evolutionary Trait Loss Reveal Regulators of a Small RNA That Controls Multicellular Development in Myxobacteria. J Bacteriol. 2016;198:3142-3151 pubmed
    ..Many myxobacteria initiate a process of multicellular fruiting body development upon starvation, but key features of the ..
  50. Cao P, Wall D. Self-identity reprogrammed by a single residue switch in a cell surface receptor of a social bacterium. Proc Natl Acad Sci U S A. 2017;114:3732-3737 pubmed publisher
    ..In myxobacteria, cells identify related individuals through a polymorphic cell surface receptor, TraA...
  51. Chen I, Velicer G, Yu Y. Divergence of functional effects among bacterial sRNA paralogs. BMC Evol Biol. 2017;17:199 pubmed publisher
    ..Previous work has shown that Pxr appears to have a recent origin within a sub-clade of the myxobacteria, which allowed us to infer the most recent common ancestor of pxr and examine the divergence of Pxr since its ..
  52. Cernava T, Erlacher A, Aschenbrenner I, Krug L, Lassek C, Riedel K, et al. Deciphering functional diversification within the lichen microbiota by meta-omics. Microbiome. 2017;5:82 pubmed publisher
    ..Five highly abundant bacterial orders-Sphingomonadales, Rhodospirillales, Myxococcales, Chthoniobacterales, and Sphingobacteriales-harbor functions that are of substantial importance for the ..
  53. Charousová I, Steinmetz H, Medo J, Javoreková S, Wink J. Soil myxobacteria as a potential source of polyketide-peptide substances. Folia Microbiol (Praha). 2017;62:305-315 pubmed publisher
    b>Myxobacteria, a group of antimicrobial producing bacteria, have been successfully cultured and characterized from ten soil samples collected from different parts of Slovakia...
  54. Brooks R, Blanchard M, Clothier K, Fish S, Anderson M, Stott J. Characterization of Pajaroellobacter abortibovis, the etiologic agent of epizootic bovine abortion. Vet Microbiol. 2016;192:73-80 pubmed publisher to analysis of the 16S ribosomal RNA (rRNA) gene (AF503916), which placed this bacterium in the order Myxococcales, suborder Sorangiineae, family Polyangiaceae and most closely related to Sorangium cellulosum...
  55. Bock T, Kasten J, Muller R, Blankenfeldt W. Crystal Structure of the HMG-CoA Synthase MvaS from the Gram-Negative Bacterium Myxococcus xanthus. Chembiochem. 2016;17:1257-62 pubmed publisher
    ..In myxobacteria, this enzyme is also involved in a recently discovered alternative and acetyl-CoA-dependent isovaleryl CoA ..
  56. Young B, Delatolla R, Abujamel T, Kennedy K, Laflamme E, Stintzi A. Rapid start-up of nitrifying MBBRs at low temperatures: nitrification, biofilm response and microbiome analysis. Bioprocess Biosyst Eng. 2017;40:731-739 pubmed publisher
    ..Peripheral microorganisms such as Myxococcales, a rapid EPS producer, appear to have contributed to the recovery and stabilization of the biofilm.
  57. Steinmetz H, Li J, Fu C, Zaburannyi N, Kunze B, Harmrolfs K, et al. Isolation, Structure Elucidation, and (Bio)Synthesis of Haprolid, a Cell-Type-Specific Myxobacterial Cytotoxin. Angew Chem Int Ed Engl. 2016;55:10113-7 pubmed publisher
    b>Myxobacteria are well-established sources for novel natural products exhibiting intriguing bioactivities. We here report on haprolid (1) isolated from Byssovorax cruenta Har1...
  58. Bhople S, Gaikwad S, Deshmukh S, Bonde S, Gade A, Sen S, et al. Myxobacteria-mediated synthesis of silver nanoparticles and their impregnation in wrapping paper used for enhancing shelf life of apples. IET Nanobiotechnol. 2016;10:389-394 pubmed publisher
    The authors report Myxobacteria virescens (M...
  59. Seccareccia I, Kovács Ã, Gallegos Monterrosa R, Nett M. Unraveling the predator-prey relationship of Cupriavidus necator and Bacillus subtilis. Microbiol Res. 2016;192:231-238 pubmed publisher
    ..subtilis to avoid predation by C. necator. In contrast to the interaction with predatory myxobacteria, however, an intact spore coat is not required for resistance...
  60. Kumar S, Yadav A, Chambel P, Kaur R. Molecular and functional characterization of myxobacteria isolated from soil in India. 3 Biotech. 2017;7:112 pubmed publisher
    ..Pyxidicoccus sp., Myxococcus sp., Cystobacter sp. and Archangium sp. The myxobacteria were functionally characterized to assess their ability to produce antibacterial and anticancer metabolites...
  61. Yue X, Cui X, Zhang Z, Peng R, Zhang P, Li Z, et al. A bacterial negative transcription regulator binding on an inverted repeat in the promoter for epothilone biosynthesis. Microb Cell Fact. 2017;16:92 pubmed publisher
    ..A dozen biosynthetic gene clusters for secondary metabolites have been reported in myxobacteria, but a few regulation factors have been identified...
  62. Lezcano M, Velázquez D, Quesada A, El Shehawy R. Diversity and temporal shifts of the bacterial community associated with a toxic cyanobacterial bloom: An interplay between microcystin producers and degraders. Water Res. 2017;125:52-61 pubmed publisher
    ..g., orders Myxococcales, Ellin6067, Spirobacillales and Cytophagales) were the most representative and suggest their possible ..
  63. Zhang L, Lueders T. Micropredator niche differentiation between bulk soil and rhizosphere of an agricultural soil depends on bacterial prey. FEMS Microbiol Ecol. 2017;93: pubmed publisher
    ..Amongst the bacteria, only a few myxobacteria sequestered C from A...
  64. Bock T, Reichelt J, Muller R, Blankenfeldt W. The Structure of LiuC, a 3-Hydroxy-3-Methylglutaconyl CoA Dehydratase Involved in Isovaleryl-CoA Biosynthesis in Myxococcus xanthus, Reveals Insights into Specificity and Catalysis. Chembiochem. 2016;17:1658-64 pubmed publisher
    b>Myxobacteria are able to produce the important metabolite isovaleryl coenzyme?A by a route other than leucine degradation. The first step into this pathway is mediated by LiuC, a member of the 3-methylglutaconyl CoA hydratases (MGCH)...
  65. Babujia L, Silva A, Nakatani A, Cantão M, Vasconcelos A, Visentainer J, et al. Impact of long-term cropping of glyphosate-resistant transgenic soybean [Glycine max (L.) Merr.] on soil microbiome. Transgenic Res. 2016;25:425-40 pubmed publisher
    ..classes (Alphaproteobacteria, Actinomycetales, Solibacteres) and orders (Rhizobiales, Burkholderiales, Myxococcales, Pseudomonadales), as well as some functional subsystems (clustering-based subsystems, carbohydrates, amino ..
  66. Landwehr W, Wolf C, Wink J. Actinobacteria and Myxobacteria-Two of the Most Important Bacterial Resources for Novel Antibiotics. Curr Top Microbiol Immunol. 2016;398:273-302 pubmed publisher
    ..Actinobacteria have been screened for many years, whereas the Myxobacteria have been underestimated in the past...
  67. Sharma G, Khatri I, Subramanian S. Complete Genome of the Starch-Degrading Myxobacteria Sandaracinus amylolyticus DSM 53668T. Genome Biol Evol. 2016;8:2520-9 pubmed publisher
    b>Myxobacteria are members of ?-proteobacteria and are typified by large genomes, well-coordinated social behavior, gliding motility, and starvation-induced fruiting body formation. Here, we report the 10...
  68. Sharma G, Khatri I, Subramanian S. Comparative Genomics of Myxobacterial Chemosensory Systems. J Bacteriol. 2018;200: pubmed publisher
    ..relatedness between different CSS, and six novel CSS ("extra CSS" [ECSS]) were thus identified in the myxobacteria besides the previously reported Che1 to Che8 systems from M...
  69. Sucipto H, Pogorevc D, Luxenburger E, Wenzel S, Muller R. Heterologous production of myxobacterial ?-pyrone antibiotics in Myxococcus xanthus. Metab Eng. 2017;44:160-170 pubmed publisher
    Myxopyronins (MXN) and corallopyronins (COR) are structurally related ?-pyrone antibiotics from myxobacteria that represent a highly promising compound class for the development of broad-spectrum antibacterial therapeutic agents...
  70. Treuner Lange A, Bruckskotten M, Rupp O, Goesmann A, Søgaard Andersen L. Complete Genome Sequence of the Fruiting Myxobacterium Myxococcus macrosporus Strain DSM 14697, Generated by PacBio Sequencing. Genome Announc. 2017;5: pubmed publisher
    Members of the Myxococcales order initiate a developmental program in response to starvation that culminates in formation of spore-filled fruiting bodies...
  71. Rox K, Jansen R, Loof T, Gillen C, Bernecker S, Walker M, et al. Linoleic and palmitoleic acid block streptokinase-mediated plasminogen activation and reduce severity of invasive group A streptococcal infection. Sci Rep. 2017;7:11798 pubmed publisher
    ..Starting from a myxobacterial natural products screening campaign, we identified two fatty acids isolated from myxobacteria, linoleic and palmitoleic acid, specifically blocking streptokinase-mediated activation of plasminogen and ..
  72. Nava Sedeño J, Hatzikirou H, Peruani F, Deutsch A. Extracting cellular automaton rules from physical Langevin equation models for single and collective cell migration. J Math Biol. 2017;75:1075-1100 pubmed publisher
    ..Both kinds of alignment have been observed in biological systems such as swarms of amoebae and myxobacteria. Polar alignment causes cells to align their velocities parallel to each other, whereas nematic alignment ..
  73. Beck S, Henß L, Weidner T, Herrmann J, Müller R, Chao Y, et al. Identification of entry inhibitors of Ebola virus pseudotyped vectors from a myxobacterial compound library. Antiviral Res. 2016;132:85-91 pubmed publisher
    b>Myxobacteria produce secondary metabolites many of which were described to have various biological effects including anti-fungal, anti-bacterial and anti-viral activity...
  74. Hoffmann M, Auerbach D, Panter F, Hoffmann T, Dorrestein P, Muller R. Homospermidine Lipids: A compound class specifically formed during fruiting body formation of Myxococcus xanthus DK1622. ACS Chem Biol. 2017;: pubmed publisher
    The fascinating ability of myxobacteria to form multicellular spore filled fruiting bodies under starvation condition was widely studied as a model for cooperative microbial behavior...
  75. Scheel A, Stevens A. Wavenumber selection in coupled transport equations. J Math Biol. 2017;75:1047-1073 pubmed publisher
    ..We comment on possible implications for rippling patterns observed in colonies of myxobacteria.
  76. Welly B, Miller M, Stott J, Blanchard M, Islas Trejo A, O Rourke S, et al. Genome Report: Identification and Validation of Antigenic Proteins from Pajaroellobacter abortibovis Using De Novo Genome Sequence Assembly and Reverse Vaccinology. G3 (Bethesda). 2017;7:321-331 pubmed publisher
    ..predicts that this bacterium is most closely related to the organisms of the order Myxococcales, referred to as Myxobacteria. In silico prediction of vaccine candidates was performed using a reverse vaccinology approach resulting ..
  77. Yu Y, Cooper E, Velicer G. A conserved stem of the Myxococcus xanthus sRNA Pxr controls sRNA accumulation and multicellular development. Sci Rep. 2017;7:15411 pubmed publisher
    ..SL1 and SL2 are highly conserved across the myxobacteria, whereas SL3 is much more variable...
  78. Treuner Lange A, Bruckskotten M, Rupp O, Goesmann A, Søgaard Andersen L. Complete Genome Sequence of the Fruiting Myxobacterium Melittangium boletus DSM 14713. Genome Announc. 2017;5: pubmed publisher
    ..of spore-filled fruiting bodies in response to starvation represents a hallmark of many members of the order Myxococcales Here, we present the complete 9...
  79. Treuner Lange A, Bruckskotten M, Rupp O, Goesmann A, Søgaard Andersen L. Draft Genome Sequence of the Fruiting Myxobacterium Nannocystis exedens DSM 71. Genome Announc. 2017;5: pubmed publisher
    In response to starvation, members of the order Myxococcales form morphologically very different fruiting bodies...
  80. Treuner Lange A, Bruckskotten M, Rupp O, Goesmann A, Søgaard Andersen L. Whole-Genome Sequence of the Fruiting Myxobacterium Cystobacter fuscus DSM 52655. Genome Announc. 2017;5: pubmed publisher
    Among myxobacteria, the genus Cystobacter is known not only for fruiting body formation but also for formation of secondary metabolites, such as cystobactamids and cystothiazols...