Bacteroides thetaiotaomicron

Summary

Alias: "Bacillus thetaiotaomicron" Distaso 1912, "Bacteroides fragilis subsp. thetaiotaomicron" (Distaso 1912) Holdeman and Moore 1970, "Pseudobacterium thetaiotaomicron" (Distaso 1912) Krasil'nikov 1949, "Sphaerocillus thetaiotaomicron" (Distaso 1912) Prevot 1938, Bacillus thetaiotaomicron, Bacteroides fragilis subsp. thetaiotaomicron, Bacteroides thetaiotaomicron (Distaso 1912) Castellani and Chalmers 1919, Pseudobacterium thetaiotaomicron, Sphaerocillus thetaiotaomicron

Top Publications

  1. Seng P, Bayle S, Alliez A, Romain F, Casanova D, Stein A. The microbial epidemiology of breast implant infections in a regional referral centre for plastic and reconstructive surgery in the south of France. Int J Infect Dis. 2015;35:62-6 pubmed publisher
    ..g., Bacteroides thetaiotaomicron, Corynebacterium simulans, Dermabacter hominis, Finegoldia magna, and Peptoniphilus harei...
  2. Watanabe M, Fukiya S, Yokota A. Comprehensive evaluation of the bactericidal activities of free bile acids in the large intestine of humans and rodents. J Lipid Res. 2017;58:1143-1152 pubmed publisher
    ..effects and bactericidal activities to Blautia coccoides JCM 1395T and Bacteroides thetaiotaomicron DSM 2079T, commonly represented in the human and rodent gut microbiota...
  3. Kasai C, Sugimoto K, Moritani I, Tanaka J, Oya Y, Inoue H, et al. Comparison of the gut microbiota composition between obese and non-obese individuals in a Japanese population, as analyzed by terminal restriction fragment length polymorphism and next-generation sequencing. BMC Gastroenterol. 2015;15:100 pubmed publisher
    ..ventriosum, Ruminococcus bromii, Ruminococcus obeum; non-obese: Bacteroides faecichinchillae, Bacteroides thetaiotaomicron, Blautia wexlerae, Clostridium bolteae, Flavonifractor plautii)...
  4. Le Bihan G, Sicard J, Garneau P, Bernalier Donadille A, Gobert A, Garrivier A, et al. The NAG Sensor NagC Regulates LEE Gene Expression and Contributes to Gut Colonization by Escherichia coli O157:H7. Front Cell Infect Microbiol. 2017;7:134 pubmed publisher
    ..Finally, we demonstrate that NAG and NANA as well as the metabolic activity of Bacteroides thetaiotaomicron affect the in vivo fitness of EHEC in a NagC-dependent manner...
  5. Bondarenko O, Ivask A, Kahru A, Vija H, Titma T, Visnapuu M, et al. Bacterial polysaccharide levan as stabilizing, non-toxic and functional coating material for microelement-nanoparticles. Carbohydr Polym. 2016;136:710-20 pubmed publisher
    ..In addition, levan attached to cobalt NPs remained accessible as a substrate for the colon bacteria Bacteroides thetaiotaomicron. We suggest that the combination of levan and nutritionally important microelements in the form of NPs ..
  6. Ouwerkerk J, de Vos W, Belzer C. Glycobiome: bacteria and mucus at the epithelial interface. Best Pract Res Clin Gastroenterol. 2013;27:25-38 pubmed publisher
    ..extracellular proteins, and include mucus-degrading specialists such as Akkermansia muciniphila and Bacteroides thetaiotaomicron. This review is focussed on the host-microbe interactions within the glycan landscape at the epithelial ..
  7. Zhang P, Sun F, Cheng X, Li X, Mu H, Wang S, et al. Preparation and biological activities of an extracellular polysaccharide from Rhodopseudomonas palustris. Int J Biol Macromol. 2019;131:933-940 pubmed publisher
    ..was shown to promote the growth of resident beneficial gut microbiotasuch as Lactobacillus reuteri, Bacteroides thetaiotaomicron and Akkermansia muciniphila...
  8. Kalay G, Dalgic N, Bozan T, Ulger Toprak N, Bayraktar B, Soyletir G. Polymicrobial anaerobic meningitis caused by Bacteroides fragilis, Bacteroides thetaiotaomicron, Fusobacterium necrophorum and Slackia exigua in a patient with mastoiditis following otitis media. Anaerobe. 2019;56:95-97 pubmed publisher
    ..This is the first case in the literature in which a patient survived childhood polymicrobial anaerobic meningitis diagnosed by MALDI-TOF MS (Matrix Assisted Laser Desorption Ionization - Time of Flight Mass Spectrometry). ..
  9. Goulas T, Garcia Ferrer I, Hutcherson J, Potempa B, Potempa J, Scott D, et al. Structure of RagB, a major immunodominant outer-membrane surface receptor antigen of Porphyromonas gingivalis. Mol Oral Microbiol. 2016;31:472-485 pubmed publisher
    ..Overall, PgRagB shows substantial structural similarity with Bacteroides thetaiotaomicron SusD and Tannerella forsythia NanU, which are, respectively, engaged in binding and uptake of malto-..

More Information

Publications121 found, 100 shown here

  1. Li M, Li G, Shang Q, Chen X, Liu W, Pi X, et al. In vitro fermentation of alginate and its derivatives by human gut microbiota. Anaerobe. 2016;39:19-25 pubmed publisher
    ..from human fecal samples and were identified as Bacteroides ovatus, Bacteroides xylanisolvens, and Bacteroides thetaiotaomicron. Alg, MO and GO can increase the production level of short chain fatty acids (SCFA), but GO generates ..
  2. Martín Díaz J, Garcia Aljaro C, Pascual Benito M, Galofré B, Blanch A, Lucena F. Microcosms for evaluating microbial indicator persistence and mobilization in fluvial sediments during rainfall events. Water Res. 2017;123:623-631 pubmed publisher
    ..coli, 36 days for bacteriophages infecting Bacteroides thetaiotaomicron strain GA17 and more than 42 days for qPCR-detected E...
  3. Hehemann J, Reintjes G, Klassen L, Smith A, Ndeh D, Arnosti C, et al. Single cell fluorescence imaging of glycan uptake by intestinal bacteria. ISME J. 2019;: pubmed publisher
    ..glycans from the cell walls of yeast and plants, respectively, were fluorescently labeled and fed to Bacteroides thetaiotaomicron VPI-5482...
  4. Bhattarai Y, Williams B, Battaglioli E, Whitaker W, Till L, Grover M, et al. Gut Microbiota-Produced Tryptamine Activates an Epithelial G-Protein-Coupled Receptor to Increase Colonic Secretion. Cell Host Microbe. 2018;23:775-785.e5 pubmed publisher
    ..GF mice colonized by Bacteroides thetaiotaomicron engineered to produce tryptamine exhibit accelerated GI transit...
  5. Gibb K, Schobben X, Christian K. Frogs host faecal bacteria typically associated with humans. Can J Microbiol. 2017;63:633-637 pubmed publisher
    ..were isolated from both faecal and skin wash samples, and specific markers (Enterococcus faecium and Bacteroides thetaiotaomicron) were found in frog faeces, demonstrating that these markers are not human- or mammalian-specific...
  6. Cvitešić A, Sabljić I, Makarevic J, Abramić M. Novel dipeptidyl hydroxamic acids that inhibit human and bacterial dipeptidyl peptidase III. J Enzyme Inhib Med Chem. 2016;31:40-45 pubmed
    ..and examined their influence on the activity of hDPP III and DPP III from the human gut symbiont Bacteroides thetaiotaomicron. The extent of inhibition of hDPP III, but not of bacterial enzyme, was dependent on the amino acid in ..
  7. Palmer L, Skaar E. Cuts Both Ways: Proteases Modulate Virulence of Enterohemorrhagic Escherichia coli. MBio. 2019;10: pubmed publisher
    ..Proteases produced by EHEC and the prevalent human commensal Bacteroides thetaiotaomicron cleave proteins in the EHEC T3SS translocon that modulate T3SS function. B...
  8. Cullen T, Schofield W, Barry N, Putnam E, Rundell E, Trent M, et al. Gut microbiota. Antimicrobial peptide resistance mediates resilience of prominent gut commensals during inflammation. Science. 2015;347:170-5 pubmed publisher
    ..b>Bacteroides thetaiotaomicron mutants that fail to remove a single phosphate group from their LPS were displaced from the microbiota ..
  9. Louis P. Different Substrate Preferences Help Closely Related Bacteria To Coexist in the Gut. MBio. 2017;8: pubmed publisher
    ..glycan prioritization in two closely related human gut bacteria, Bacteroides ovatus and Bacteroides thetaiotaomicron, on complex glycan mixtures that both organisms can degrade...
  10. Chatzidaki Livanis M, Comstock L. Friend turned foe: a role for bacterial sulfatases in colitis. Cell Host Microbe. 2015;17:540-1 pubmed publisher
    ..In this issue of Cell Host & Microbe, Hickey et al. (2015) show that sulfatases of Bacteroides thetaiotaomicron are required for its outer membrane vesicles to transit to underlying host immune cells and cause ..
  11. Hottin A, Scandolera A, Duca L, Wright D, Davies G, Behr J. A second-generation ferrocene-iminosugar hybrid with improved fucosidase binding properties. Bioorg Med Chem Lett. 2016;26:1546-1549 pubmed publisher
    ..The compound showed strong affinity for fucosidase from bovine kidney (Ki=23 nM) and from Bacteroides thetaiotaomicron (Ki=150 nM), displaying a 10-fold tighter binding affinity for these enzymes than the previous analogs...
  12. Yao L, Seaton S, Ndousse Fetter S, Adhikari A, DiBenedetto N, Mina A, et al. A selective gut bacterial bile salt hydrolase alters host metabolism. elife. 2018;7: pubmed publisher
    ..Using isogenic strains of wild-type and BSH-deleted Bacteroides thetaiotaomicron, we selectively modulated the levels of the bile acid tauro-β-muricholic acid in monocolonized ..
  13. Rigden D, Eberhardt R, Gilbert H, Xu Q, Chang Y, Godzik A. Structure- and context-based analysis of the GxGYxYP family reveals a new putative class of glycoside hydrolase. BMC Bioinformatics. 2014;15:196 pubmed publisher
    ..in the gut microbiota, and are found in Polysaccharide Utilization Loci in the gut symbiont Bacteroides thetaiotaomicron, suggesting their involvement in polysaccharide metabolism, but little else is known of the function of ..
  14. Hrncirova L, Hudcovic T, Sukova E, Machova V, Trckova E, Krejsek J, et al. Human gut microbes are susceptible to antimicrobial food additives in vitro. Folia Microbiol (Praha). 2019;: pubmed publisher
    ..susceptible to additives than microbes with known proinflammatory or colitogenic properties, such as Bacteroides thetaiotaomicron or Enterococcus faecalis...
  15. Shumaker A, Laclare McEneany V, Coyne M, Silver P, Comstock L. Identification of a Fifth Antibacterial Toxin Produced by a Single Bacteroides fragilis Strain. J Bacteriol. 2019;201: pubmed publisher
    ..strains that are BSAP-4 resistant under the conditions of our assay confer BSAP-4 sensitivity to Bacteroides thetaiotaomicron when constitutively expressed...
  16. Krejzová J, Simon P, Kalachova L, Kulik N, Bojarová P, Marhol P, et al. Inhibition of GlcNAc-processing glycosidases by C-6-azido-NAG-thiazoline and its derivatives. Molecules. 2014;19:3471-88 pubmed publisher
    ..from Talaromyces flavus, Streptomyces plicatus (both GH20) and β-N-acetylglucosaminidases from Bacteroides thetaiotaomicron and humans (both GH84)...
  17. Wegorzewska M, Glowacki R, Hsieh S, Donermeyer D, Hickey C, Horvath S, et al. Diet modulates colonic T cell responses by regulating the expression of a Bacteroides thetaiotaomicron antigen. Sci Immunol. 2019;4: pubmed publisher
    ..We generated a CD4+ T cell hybridoma, BθOM, specific for Bacteroides thetaiotaomicron (B. theta)...
  18. Volkers G, Schuldt L, Palm G, Wright G, Hinrichs W. Crystallization and preliminary X-ray crystallographic analysis of the tetracycline-degrading monooxygenase TetX2 from Bacteroides thetaiotaomicron. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010;66:611-4 pubmed publisher
    The flavin-dependent monooxygenase TetX2 from Bacteroides thetaiotaomicron confers resistance against tetracyclines in aerobically grown Escherichia coli...
  19. Townsend G, Han W, Schwalm N, Raghavan V, Barry N, Goodman A, et al. Dietary sugar silences a colonization factor in a mammalian gut symbiont. Proc Natl Acad Sci U S A. 2019;116:233-238 pubmed publisher
    ..necessary for gut colonization, but not for utilization of these sugars, by the human gut commensal Bacteroides thetaiotaomicron Silencing by fructose and glucose requires the 5' leader region of the mRNA specifying the protein, ..
  20. Pham H, Boger M, Dijkhuizen L, van Leeuwen S. Stimulatory effects of novel glucosylated lactose derivatives GL34 on growth of selected gut bacteria. Appl Microbiol Biotechnol. 2019;103:707-718 pubmed publisher
    ..Lactobacilli and the commensal bacteria Escherichia coli Nissle and Bacteroides thetaiotaomicron only degraded the F2 compound α-D-Glcp-(1 → 2)-[β-D-Galp-(1 → 4)-]D-Glcp, constituting ..
  21. Valguarnera E, Scott N, Azimzadeh P, Feldman M. Surface Exposure and Packing of Lipoproteins into Outer Membrane Vesicles Are Coupled Processes in Bacteroides. mSphere. 2018;3: pubmed publisher
    ..Here, we revisited the protein composition of Bacteroides thetaiotaomicron OMVs by mass spectrometry...
  22. Ndeh D, Munoz Munoz J, Cartmell A, Bulmer D, Wills C, Henrissat B, et al. The human gut microbe Bacteroides thetaiotaomicron encodes the founding member of a novel glycosaminoglycan-degrading polysaccharide lyase family PL29. J Biol Chem. 2018;293:17906-17916 pubmed publisher
    ..HGM is therefore of interest and has been extensively investigated in the model human gut microbe Bacteroides thetaiotaomicron. The presence of as-yet uncharacterized GAG-inducible genes in its genome and of related species, ..
  23. Böger M, Hekelaar J, van Leeuwen S, Dijkhuizen L, Lammerts van Bueren A. Structural and functional characterization of a family GH53 β-1,4-galactanase from Bacteroides thetaiotaomicron that facilitates degradation of prebiotic galactooligosaccharides. J Struct Biol. 2019;205:1-10 pubmed publisher
    ..b>Bacteroides thetaiotaomicron is a prominent human colon commensal bacterial species that hydrolyzes GOS using an extracellular ..
  24. Feuerbaum S, Saile N, Pohlentz G, Muthing J, Schmidt H. De-O-Acetylation of mucin-derived sialic acids by recombinant NanS-p esterases of Escherichia coli O157:H7 strain EDL933. Int J Med Microbiol. 2018;308:1113-1120 pubmed publisher
    ..Moreover, we could demonstrate by HPTLC analyses that recombinant Bacteroides thetaiotaomicron sialidase (BTSA-His) was able to cleave Neu5Ac and Neu5,9Ac2 from BSM and that the ..
  25. Lammerts van Bueren A, Mulder M, Leeuwen S, Dijkhuizen L. Prebiotic galactooligosaccharides activate mucin and pectic galactan utilization pathways in the human gut symbiont Bacteroides thetaiotaomicron. Sci Rep. 2017;7:40478 pubmed publisher
    ..Here we studied the effects of GOS utilization on a prominent gut symbiont, Bacteroides thetaiotaomicron, which has been previously shown to consume HMOs via mucin O-glycan degradation pathways...
  26. Cartmell A, Munoz Munoz J, Briggs J, Ndeh D, Lowe E, Basle A, et al. A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation. Nat Microbiol. 2018;3:1314-1326 pubmed publisher
    ..Here we explore how the HGM organism Bacteroides thetaiotaomicron metabolizes AGPs...
  27. Wu T, Pei J, Ge L, Wang Z, Ding G, Xiao W, et al. Characterization of a α-l-rhamnosidase from Bacteroides thetaiotaomicron with high catalytic efficiency of epimedin C. Bioorg Chem. 2018;81:461-467 pubmed publisher
    In this study, a α-l-rhamnosidase gene from Bacteroides thetaiotaomicron VPI-5482 was cloned and expressed in Escherichia coli. The specific activity of rhamnosidase was 0.57 U/mg in LB medium with 0...
  28. Zimmer Faust A, Thulsiraj V, Lee C, Whitener V, Rugh M, Mendoza Espinosa L, et al. Multi-tiered approach utilizing microbial source tracking and human associated-IMS/ATP for surveillance of human fecal contamination in Baja California, Mexico. Sci Total Environ. 2018;640-641:475-484 pubmed publisher
    ..The HF183 and Bacteroides thetaiotaomicron (B...
  29. Porter N, Luís A, Martens E. Bacteroides thetaiotaomicron. Trends Microbiol. 2018;26:966-967 pubmed publisher
    This infographic on Bacteroides thetaiotaomicron (Bt) explores the ability of this microbe to digest a broad array of complex carbohydrates, alter its surface features, and its emerging role in gastrointestinal diseases...
  30. Edwards L, Lucas M, Edwards E, Torrente F, Heuschkel R, Klein N, et al. Aberrant response to commensal Bacteroides thetaiotaomicron in Crohn's disease: an ex vivo human organ culture study. Inflamm Bowel Dis. 2011;17:1201-8 pubmed publisher
    ..While IL-8 responses to O42 and LGG varied with disease status and anatomical location, B. theta consistently induced significant IL-8 both in ileal and colonic CD tissue, which was not seen in control, healthy tissue. ..
  31. Adamberg K, Adamberg S, Ernits K, Larionova A, Voor T, Jaagura M, et al. Composition and metabolism of fecal microbiota from normal and overweight children are differentially affected by melibiose, raffinose and raffinose-derived fructans. Anaerobe. 2018;52:100-110 pubmed publisher
    ..samples from overweight or normal-weight children, from healthy adult volunteers and a pure culture of Bacteroides thetaiotaomicron as a reference bacterium for colon microbiota...
  32. Liang L, Goh S, Vergara G, Fang H, Rezaeinejad S, Chang S, et al. Alternative fecal indicators and their empirical relationships with enteric viruses, Salmonella enterica, and Pseudomonas aeruginosa in surface waters of a tropical urban catchment. Appl Environ Microbiol. 2015;81:850-60 pubmed publisher
    ..the relationships between alternative microbial indicators of potential human fecal contamination (Bacteroides thetaiotaomicron, Methanobrevibacter smithii, human polyomaviruses [HPyVs], and F+ and somatic coliphages) and pathogens ..
  33. Ferreyra J, Wu K, Hryckowian A, Bouley D, Weimer B, Sonnenburg J. Gut microbiota-produced succinate promotes C. difficile infection after antibiotic treatment or motility disturbance. Cell Host Microbe. 2014;16:770-7 pubmed publisher
    ..In the presence of the gut symbiont Bacteroides thetaiotaomicron, C...
  34. Lammerts van Bueren A, Saraf A, Martens E, Dijkhuizen L. Differential Metabolism of Exopolysaccharides from Probiotic Lactobacilli by the Human Gut Symbiont Bacteroides thetaiotaomicron. Appl Environ Microbiol. 2015;81:3973-83 pubmed publisher
    ..In this study, it is demonstrated that the human gut commensal species Bacteroides thetaiotaomicron efficiently metabolizes fructan exopolysaccharide (EPS) synthesized by probiotic Lactobacillus reuteri ..
  35. Hickey C, Kuhn K, Donermeyer D, Porter N, Jin C, Cameron E, et al. Colitogenic Bacteroides thetaiotaomicron Antigens Access Host Immune Cells in a Sulfatase-Dependent Manner via Outer Membrane Vesicles. Cell Host Microbe. 2015;17:672-80 pubmed publisher
    ..Using genetically susceptible mice (dnKO) that develop spontaneous, fulminant colitis, triggered by Bacteroides thetaiotaomicron (B...
  36. Oliveira A, Oliveira A, Franco L, Ferencs M, Ferreira J, Bachi S, et al. 5-Nitroimidazole-derived Schiff bases and their copper(II) complexes exhibit potent antimicrobial activity against pathogenic anaerobic bacteria. Biometals. 2018;31:571-584 pubmed publisher
    ..The compounds exhibited in vitro antibacterial activity against Bacteroides fragilis, Bacteroides thetaiotaomicron, Bacteroides vulgatus, Bacteroides ovatus, Parabacteroides distasonis and Fusubacterium nucleatum ..
  37. Joglekar P, Sonnenburg E, Higginbottom S, Earle K, Morland C, Shapiro Ward S, et al. Genetic Variation of the SusC/SusD Homologs from a Polysaccharide Utilization Locus Underlies Divergent Fructan Specificities and Functional Adaptation in Bacteroides thetaiotaomicron Strains. mSphere. 2018;3: pubmed publisher
    ..approaches, we identified differences in the fructan utilization profiles of two closely related Bacteroides thetaiotaomicron strains. B...
  38. Nakajima A, Vogelzang A, Maruya M, Miyajima M, Murata M, Son A, et al. IgA regulates the composition and metabolic function of gut microbiota by promoting symbiosis between bacteria. J Exp Med. 2018;215:2019-2034 pubmed publisher
    ..We found that a heavily glycosylated monoclonal IgA recognizing ovalbumin coats Bacteroides thetaiotaomicron (B. theta), a prominent gut symbiont of the phylum Bacteroidetes...
  39. Manfredi P, Lauber F, Renzi F, Hack K, Hess E, Cornelis G. New iron acquisition system in Bacteroidetes. Infect Immun. 2015;83:300-10 pubmed publisher
    ..The archetype system is the Bacteroides thetaiotaomicron Sus system, devoted to starch utilization...
  40. Karunatilaka K, Cameron E, Martens E, Koropatkin N, Biteen J. Superresolution imaging captures carbohydrate utilization dynamics in human gut symbionts. MBio. 2014;5:e02172 pubmed publisher
    ..into carbohydrate catabolism in gut symbionts, we studied starch processing in real time in the model Bacteroides thetaiotaomicron starch utilization system (Sus) by single-molecule fluorescence...
  41. Stentz R, Horn N, Cross K, Salt L, Brearley C, Livermore D, et al. Cephalosporinases associated with outer membrane vesicles released by Bacteroides spp. protect gut pathogens and commensals against β-lactam antibiotics. J Antimicrob Chemother. 2015;70:701-9 pubmed publisher
    ..the putative class A β-lactamase gene (locus tag BT_4507) found in the genome of the human commensal Bacteroides thetaiotaomicron was constructed and a phenotypic analysis performed...
  42. Iversen H, Lindbäck T, L Abée Lund T, Roos N, Aspholm M, Stenfors Arnesen L. The gut bacterium Bacteroides thetaiotaomicron influences the virulence potential of the enterohemorrhagic Escherichia coli O103:H25. PLoS ONE. 2015;10:e0118140 pubmed publisher
  43. Cameron E, Kwiatkowski K, Lee B, Hamaker B, Koropatkin N, Martens E. Multifunctional nutrient-binding proteins adapt human symbiotic bacteria for glycan competition in the gut by separately promoting enhanced sensing and catalysis. MBio. 2014;5:e01441-14 pubmed publisher
    ..The Bacteroides thetaiotaomicron starch utilization system (Sus) is a model for nutrient acquisition by symbiotic gut bacteria, which ..
  44. Knaus T, Uhl M, Monschein S, Moratti S, Gruber K, Macheroux P. Structure and stability of an unusual zinc-binding protein from Bacteroides thetaiotaomicron. Biochim Biophys Acta. 2014;1844:2298-305 pubmed publisher
    The crystal structure of a putative protease from Bacteroides thetaiotaomicron (ppBat) suggested the presence of a zinc ion in each protomer of the dimer as well as a flavin in the dimer interface...
  45. Curtis M, Hu Z, Klimko C, Narayanan S, DEBERARDINIS R, Sperandio V. The gut commensal Bacteroides thetaiotaomicron exacerbates enteric infection through modification of the metabolic landscape. Cell Host Microbe. 2014;16:759-69 pubmed publisher
    ..A predominant member of the microbiota, Bacteroides thetaiotaomicron (Bt), is resident at EHEC attachment sites...
  46. Maier E, Anderson R, Roy N. Understanding how commensal obligate anaerobic bacteria regulate immune functions in the large intestine. Nutrients. 2014;7:45-73 pubmed publisher
    ..Several in vitro and in vivo studies indicate a role for Faecalibacterium prausnitzii, Bacteroides thetaiotaomicron, Bacteroides fragilis, Akkermansia muciniphila and segmented filamentous bacteria in maintaining ..
  47. Deschemin J, Noordine M, Remot A, Willemetz A, Afif C, Canonne Hergaux F, et al. The microbiota shifts the iron sensing of intestinal cells. FASEB J. 2016;30:252-61 pubmed publisher
    ..Commensal organisms (Bacteroides thetaiotaomicron VPI-5482 and Faecalibacterium prausnitzii A2-165) and a probiotic strain (Streptococcus thermophilus ..
  48. Schofield W, Zimmermann Kogadeeva M, Zimmermann M, Barry N, Goodman A. The Stringent Response Determines the Ability of a Commensal Bacterium to Survive Starvation and to Persist in the Gut. Cell Host Microbe. 2018;24:120-132.e6 pubmed publisher
    ..We report that the human gut bacterium Bacteroides thetaiotaomicron relies on the stringent response, an intracellular signaling pathway that allocates resources away from ..
  49. Takesue Y, Watanabe A, Hanaki H, Kusachi S, Matsumoto T, Iwamoto A, et al. Nationwide surveillance of antimicrobial susceptibility patterns of pathogens isolated from surgical site infections (SSI) in Japan. J Infect Chemother. 2012;18:816-26 pubmed publisher
    ..6 % to clindamycin, 5.7 % to cefmetazole, 2.9 % to TAZ/PIPC and IPM, and 0 % to metronidazole (Bacteroides thetaiotaomicron; 59.1, 36.4, 0, 0, 0 %). MIC₉₀ of P...
  50. Van Wey A, Cookson A, Roy N, McNabb W, Soboleva T, Shorten P. Monoculture parameters successfully predict coculture growth kinetics of Bacteroides thetaiotaomicron and two Bifidobacterium strains. Int J Food Microbiol. 2014;191:172-81 pubmed publisher
    ..In addition, we adapted the model to describe the competition between human colonic bacteria Bacteroides thetaiotaomicron LMG 11262 and Bifidobacterium longum LMG 11047 or Bifidobacterium breve Yakult for inulin as well as ..
  51. Aalbers F, Turkenburg J, Davies G, Dijkhuizen L, Lammerts van Bueren A. Structural and Functional Characterization of a Novel Family GH115 4-O-Methyl-α-Glucuronidase with Specificity for Decorated Arabinogalactans. J Mol Biol. 2015;427:3935-46 pubmed publisher
    ..In this study, we reveal that a putative periplasmic GH115 from the human gut symbiont Bacteroides thetaiotaomicron, BtGH115A, hydrolyzes terminal 4-O-methyl-glucuronic acid residues from decorated arabinogalactan ..
  52. Haro C, García Carpintero S, Alcalá Díaz J, Gómez Delgado F, Delgado Lista J, Perez Martinez P, et al. The gut microbial community in metabolic syndrome patients is modified by diet. J Nutr Biochem. 2016;27:27-31 pubmed publisher
    ..the control group than in MetS patients, while Bacteroides fragilis group, Parabacteroides distasonis, Bacteroides thetaiotaomicron, Faecalibacterium prausnitzii, Fusobacterium nucleatum, Bifidobacterium longum, Bifidobacterium ..
  53. Chang C, Tesar C, Li X, Kim Y, Rodionov D, Joachimiak A. A novel transcriptional regulator of L-arabinose utilization in human gut bacteria. Nucleic Acids Res. 2015;43:10546-59 pubmed publisher
    ..of transcriptional regulation of sugar catabolism in commensal and prevalent human gut bacteria such as Bacteroides thetaiotaomicron remain mostly unknown...
  54. Khelaifia S, Lagier J, Nkamga V, Guilhot E, Drancourt M, Raoult D. Aerobic culture of methanogenic archaea without an external source of hydrogen. Eur J Clin Microbiol Infect Dis. 2016;35:985-91 pubmed publisher
    ..Performing aerobic cultures in the presence of Bacteroides thetaiotaomicron, which produces hydrogen, allows for cultivation of Methanobrevibacter smithii which itself produces ..
  55. Cordonnier C, Le Bihan G, Emond Rheault J, Garrivier A, Harel J, Jubelin G. Vitamin B12 Uptake by the Gut Commensal Bacteria Bacteroides thetaiotaomicron Limits the Production of Shiga Toxin by Enterohemorrhagic Escherichia coli. Toxins (Basel). 2016;8: pubmed publisher
    ..them, soluble factors produced by human gut microbiota and in particular, by the predominant species Bacteroides thetaiotaomicron (B. thetaiotaomicron), inhibit Stx2 gene expression...
  56. Taketani M, Donia M, Jacobson A, Lambris J, Fischbach M. A Phase-Variable Surface Layer from the Gut Symbiont Bacteroides thetaiotaomicron. MBio. 2015;6:e01339-15 pubmed publisher
    ..Here, we report the serendipitous discovery of a previously unknown surface structure in Bacteroides thetaiotaomicron: a surface layer composed of a protein of unknown function, BT1927...
  57. Jacobson A, Choudhury B, Fischbach M. The Biosynthesis of Lipooligosaccharide from Bacteroides thetaiotaomicron. MBio. 2018;9: pubmed publisher
    ..for understanding the biological function of Bacteroides LPS, we have identified genes in Bacteroides thetaiotaomicron VPI 5482 involved in the biosynthesis of its lipid A core and glycan, generated mutants that ..
  58. Ringwald K, Gardner J. The Bacteroides thetaiotaomicron protein Bacteroides host factor A participates in integration of the integrative conjugative element CTnDOT into the chromosome. J Bacteriol. 2015;197:1339-49 pubmed publisher
    ..This work describes the role of a protein, BHFa, and its importance in the integration reaction required for the element CTnDOT to persist in Bacteroides host cells. ..
  59. Hoffmann T, Pham H, Bridonneau C, Aubry C, Lamas B, Martin Gallausiaux C, et al. Microorganisms linked to inflammatory bowel disease-associated dysbiosis differentially impact host physiology in gnotobiotic mice. ISME J. 2016;10:460-77 pubmed publisher
    ..that are representative of inflammatory bowel disease (IBD)-associated dysbiosis: the bacteria Bacteroides thetaiotaomicron, adhesive-invasive Escherichia coli (AIEC), Ruminococcus gnavus and Roseburia intestinalis; a yeast ..
  60. Pudlo N, Urs K, Kumar S, German J, Mills D, Martens E. Symbiotic Human Gut Bacteria with Variable Metabolic Priorities for Host Mucosal Glycans. MBio. 2015;6:e01282-15 pubmed publisher
    ..We investigated the responses of Bacteroides thetaiotaomicron, a common human intestinal bacterium that metabolizes more than a dozen different polysaccharides, ..
  61. Shang Q, Yin Y, Zhu L, Li G, Yu G, Wang X. Degradation of chondroitin sulfate by the gut microbiota of Chinese individuals. Int J Biol Macromol. 2016;86:112-8 pubmed publisher
    ..In addition to Bacteroides thetaiotaomicron J1, Bacteroides thetaiotaomicron 82 and Bacteroides ovatus E3, a new CSA-degrading bacterium, ..
  62. Lu Z, Sethu R, Imlay J. Endogenous superoxide is a key effector of the oxygen sensitivity of a model obligate anaerobe. Proc Natl Acad Sci U S A. 2018;115:E3266-E3275 pubmed publisher
    ..This question was explored using Bacteroides thetaiotaomicron, a major fermentative bacterium in the human gastrointestinal tract...
  63. Takahata M, Nishino T. Antibacterial activities of tosufloxacin against anaerobic bacteria and the electron micrograph of its bactericidal effects. Chemotherapy. 1997;43:153-8 pubmed
    ..The MIC90 of tosufloxacin for clinical isolates of Bacteroides fragilis, Bacteroides vulgatus, Bacteroides thetaiotaomicron and Peptostreptococcus asaccharolyticus were 0.78, 0.39, 1.56 and 0.39 micrograms/ml, respectively...
  64. Parasuram R, Mills C, Wang Z, Somasundaram S, Beuning P, Ondrechen M. Local structure based method for prediction of the biochemical function of proteins: Applications to glycoside hydrolases. Methods. 2016;93:51-63 pubmed publisher
    ..protein BACOVA_03626 from Bacteroides ovatus (PDB 3ON6) and a hypothetical protein BT3781 from Bacteroides thetaiotaomicron (PDB 2P0V) are shown to have very strong active site matches with exo-α-1,6-mannosidases, thus ..
  65. Peterson D, Planer J, Guruge J, Xue L, Downey Virgin W, Goodman A, et al. Characterizing the interactions between a naturally primed immunoglobulin A and its conserved Bacteroides thetaiotaomicron species-specific epitope in gnotobiotic mice. J Biol Chem. 2015;290:12630-49 pubmed publisher
    ..Fusing intestinal lamina propria lymphocytes from mice monocolonized with Bacteroides thetaiotaomicron to a myeloma fusion partner allowed us to recover hybridomas that captured naturally primed, antigen-..
  66. Verhougstraete M, Martin S, Kendall A, Hyndman D, Rose J. Linking fecal bacteria in rivers to landscape, geochemical, and hydrologic factors and sources at the basin scale. Proc Natl Acad Sci U S A. 2015;112:10419-24 pubmed publisher
    ..drain 84% of Michigan's Lower Peninsula were sampled under baseflow conditions for Escherichia coli, Bacteroides thetaiotaomicron (a human source-tracking marker), landscape characteristics, and geochemical and hydrologic variables...
  67. Mert M, la Grange D, Rose S, van Zyl W. Engineering of Saccharomyces cerevisiae to utilize xylan as a sole carbohydrate source by co-expression of an endoxylanase, xylosidase and a bacterial xylose isomerase. J Ind Microbiol Biotechnol. 2016;43:431-40 pubmed publisher
    ..stipitis xylulose kinase (xyl3) together with the codon-optimized xylose isomerase (xylA) from Bacteroides thetaiotaomicron. Under aerobic conditions, the recombinant strain displayed a complete respiratory mode, resulting in ..
  68. Sadarangani S, Cunningham S, Jeraldo P, Wilson J, Khare R, Patel R. Metronidazole- and carbapenem-resistant bacteroides thetaiotaomicron isolated in Rochester, Minnesota, in 2014. Antimicrob Agents Chemother. 2015;59:4157-61 pubmed publisher
    ..Although metronidazole and carbapenem resistance have been reported in Bacteroides thetaiotaomicron, a member of the B...
  69. Charlet R, Pruvost Y, Tumba G, Istel F, Poulain D, Kuchler K, et al. Remodeling of the Candida glabrata cell wall in the gastrointestinal tract affects the gut microbiota and the immune response. Sci Rep. 2018;8:3316 pubmed publisher
    ..Enterococcus faecalis, and Bacteroides vulgatus populations, and a decrease in Lactobacillus johnsonii, Bacteroides thetaiotaomicron, and Bifidobacterium animalis in mice with DSS-induced colitis...
  70. Mayorga Reyes L, González Vázquez R, Cruz Arroyo S, Melendez Avalos A, Reyes Castillo P, Chavaro Pérez D, et al. Correlation between diet and gut bacteria in a population of young adults. Int J Food Sci Nutr. 2016;67:470-8 pubmed publisher
    ..abundance of Firmicutes and Bacteroidetes phyla, some representative bacteria of these phyla such as Bacteroides thetaiotaomicron, Prevotella, Faecalibacterium prausnitzii, Clostridium leptum and Bifidobacterium longum as a member of ..
  71. Altamimi M, Abdelhay O, Rastall R. Effect of oligosaccharides on the adhesion of gut bacteria to human HT-29 cells. Anaerobe. 2016;39:136-42 pubmed publisher
    ..and chito-oligosaccharides) on the adhesion of eight gut bacteria (Bifidobacterium bifidum ATCC 29521, Bacteroides thetaiotaomicron ATCC 29148D-5, Clostridium leptum ATCC 29065, Blautia coccoides ATCC 29236, Faecalibacterium ..
  72. Schwalm N, Townsend G, Groisman E. Multiple Signals Govern Utilization of a Polysaccharide in the Gut Bacterium Bacteroides thetaiotaomicron. MBio. 2016;7: pubmed publisher
    ..polysaccharide breakdown with simple sugar utilization was established in the mammalian gut symbiont Bacteroides thetaiotaomicron, whereby sensing of monomeric fructose regulates catabolism of both fructose and polymeric fructans...
  73. Ulaganathan T, Shi R, Yao D, Gu R, Garron M, Cherney M, et al. Conformational flexibility of PL12 family heparinases: structure and substrate specificity of heparinase III from Bacteroides thetaiotaomicron (BT4657). Glycobiology. 2017;27:176-187 pubmed publisher
    ..We have characterized structurally and enzymatically heparinase III from Bacteroides thetaiotaomicron (BtHepIII; gene BT4657), which is classified within the PL12 family. BtHepIII is a 72.5 kDa protein...
  74. Schwalm N, Townsend G, Groisman E. Prioritization of polysaccharide utilization and control of regulator activation in Bacteroides thetaiotaomicron. Mol Microbiol. 2017;104:32-45 pubmed publisher
    b>Bacteroides thetaiotaomicron is a human gut symbiotic bacterium that utilizes a myriad of host dietary and mucosal polysaccharides...
  75. Udompaisarn S, Arthan D, Somana J. Development and Validation of an Enzymatic Method To Determine Stevioside Content from Stevia rebaudiana. J Agric Food Chem. 2017;65:3223-3229 pubmed publisher
    ..Recombinant ?-glucosidase BT_3567 (rBT_3567) from Bacteroides thetaiotaomicron HB-13 exhibited selective hydrolysis of stevioside at ?-1,2-glycosidic bond to yield rubusoside and ..
  76. Večeřová R, Panáček A, Kolář M. [Effect of silver nanoparticles on anaerobic bacteria]. Klin Mikrobiol Infekc Lek. 2017;23:17-20 pubmed
    ..The following anaerobic bacteria were tested: Bacteroides fragilis, Bacteroides thetaiotaomicron, Eggerthella lenta, Propionibacterium acnes, Clostridium perfringens, Clostridium difficile and ..
  77. Kikuchi A, Okuyama M, Kato K, Osaki S, Ma M, Kumagai Y, et al. A novel glycoside hydrolase family 97 enzyme: Bifunctional ?-l-arabinopyranosidase/?-galactosidase from Bacteroides thetaiotaomicron. Biochimie. 2017;142:41-50 pubmed publisher
    ..Interestingly, mutation of Asn338 to Ala reduces the kcat/Km value for hydrolysis of p-nitrophenyl ?-l-arabinopyranoside. ..
  78. Tuson H, Foley M, Koropatkin N, Biteen J. The Starch Utilization System Assembles around Stationary Starch-Binding Proteins. Biophys J. 2018;115:242-250 pubmed publisher
    b>Bacteroides thetaiotaomicron (Bt) is a prominent member of the human gut microbiota with an extensive capacity for glycan harvest...
  79. Lu Z, Wang L, Dunaway Mariano D, Allen K. Structure-function analysis of 2-keto-3-deoxy-D-glycero-D-galactonononate-9-phosphate phosphatase defines specificity elements in type C0 haloalkanoate dehalogenase family members. J Biol Chem. 2009;284:1224-33 pubmed publisher
    ..One such gene, BT1713, from the Bacteroides thetaiotaomicron genome was recently found to encode the enzyme 2-keto-3-deoxy-d-glycero-d-galacto-9-phosphonononic acid ..
  80. Mardo K, Visnapuu T, Vija H, Aasamets A, Viigand K, Alamäe T. A Highly Active Endo-Levanase BT1760 of a Dominant Mammalian Gut Commensal Bacteroides thetaiotaomicron Cleaves Not Only Various Bacterial Levans, but Also Levan of Timothy Grass. PLoS ONE. 2017;12:e0169989 pubmed publisher
    b>Bacteroides thetaiotaomicron, an abundant commensal of the human gut, degrades numerous complex carbohydrates...
  81. Okuyama M, Matsunaga K, Watanabe K, Yamashita K, Tagami T, Kikuchi A, et al. Efficient synthesis of ?-galactosyl oligosaccharides using a mutant Bacteroides thetaiotaomicron retaining ?-galactosidase (BtGH97b). FEBS J. 2017;284:766-783 pubmed publisher
    ..The mechanism of ?-galactoside recognition is conserved among GH27, 31, 36 and 97 ?-galactosidases. The atomic coordinates (code: 5E1Q) have been deposited in the Protein Data Bank. ..
  82. Robinson L, Lewis W, Lewis A. The sialate O-acetylesterase EstA from gut Bacteroidetes species enables sialidase-mediated cross-species foraging of 9-O-acetylated sialoglycans. J Biol Chem. 2017;292:11861-11872 pubmed publisher
    ..We conclude that EstA specifically unlocks the nutritive potential of 9-O-acetylated mucus sialic acids for foraging by bacteria that otherwise are prevented from accessing this carbon source. ..
  83. Foley M, Cockburn D, Koropatkin N. The Sus operon: a model system for starch uptake by the human gut Bacteroidetes. Cell Mol Life Sci. 2016;73:2603-17 pubmed publisher
    ..The most well-studied PUL-encoded glycan-uptake system is the starch utilization system (Sus) of Bacteroides thetaiotaomicron. The Sus includes the requisite proteins for binding and degrading starch at the surface of the cell ..
  84. Munoz Munoz J, Cartmell A, Terrapon N, Basle A, Henrissat B, Gilbert H. An evolutionarily distinct family of polysaccharide lyases removes rhamnose capping of complex arabinogalactan proteins. J Biol Chem. 2017;292:13271-13283 pubmed publisher
    ..we screened the potential enzymatic functions of hypothetical proteins encoded by genes of Bacteroides thetaiotaomicron that were up-regulated by arabinogalactan proteins or AGPs...
  85. Zou K, Ren L, Ping Y, Ma K, Li H, Cao Y, et al. Identification of vaginal fluid, saliva, and feces using microbial signatures in a Han Chinese population. J Forensic Leg Med. 2016;43:126-131 pubmed publisher
    ..subunit gene of Bacteroides uniformis and Bacteroides vulgatus, and the ?-1-6 mannanase gene of Bacteroides thetaiotaomicron in feces. As a result, the detection proportions of L. crispatus, L. gasseri, L. jensenii, L...
  86. Temple M, Cuskin F, Basle A, Hickey N, Speciale G, Williams S, et al. A Bacteroidetes locus dedicated to fungal 1,6-?-glucan degradation: Unique substrate conformation drives specificity of the key endo-1,6-?-glucanase. J Biol Chem. 2017;292:10639-10650 pubmed publisher
    ..To test this hypothesis we characterized the proteins encoded by this locus in Bacteroides thetaiotaomicron, a member of the human gut microbiota...
  87. Cartmell A, Lowe E, Basle A, Firbank S, Ndeh D, Murray H, et al. How members of the human gut microbiota overcome the sulfation problem posed by glycosaminoglycans. Proc Natl Acad Sci U S A. 2017;114:7037-7042 pubmed publisher
    ..host glycosaminoglycans heparin (Hep) and heparan sulfate (HS) are high-priority carbohydrates for Bacteroides thetaiotaomicron, a prominent member of the human microbiota...
  88. Henson M, Phalak P. Microbiota dysbiosis in inflammatory bowel diseases: in silico investigation of the oxygen hypothesis. BMC Syst Biol. 2017;11:145 pubmed publisher
    ..prausnitzii, E. coli and the common gut anaerobe Bacteroides thetaiotaomicron. Application of low bulk oxygen concentrations at the biofilm boundary reproduced experimentally ..
  89. Kawata N, Tanaka M, Kakushima N, Takizawa K, Imai K, Hotta K, et al. The low incidence of bacteremia after esophageal endoscopic submucosal dissection (ESD) obviates the need for prophylactic antibiotics in esophageal ESD. Surg Endosc. 2016;30:5084-5090 pubmed
    ..Growth of Bacteroides thetaiotaomicron was only observed in one patient (1 %) with positive blood cultures immediately after ESD, and this ..
  90. L L, S G G, K Y H G. Decay kinetics of microbial source tracking (MST) markers and human adenovirus under the effects of sunlight and salinity. Sci Total Environ. 2017;574:165-175 pubmed publisher
    ..e. Bacteroides thetaiotaomicron (B. theta), Methanobrevibacter smithii (M...
  91. Galvão M, Bastos R, Acurcio L, Nascimento B, Sandes S, Arantes R, et al. Evaluation of colonisation resistance in stool of human donors using ex vivo, in vitro and in vivo assays. Benef Microbes. 2017;8:217-230 pubmed publisher
    ..Typhimurium. Mice mono-associated with Enterococcus hirae strain 8.2, Bacteroides thetaiotaomicron strain 16.2 and Lactobacillus ruminis strain 18...
  92. Ndeh D, Rogowski A, Cartmell A, Luís A, Baslé A, GRAY J, et al. Complex pectin metabolism by gut bacteria reveals novel catalytic functions. Nature. 2017;544:65-70 pubmed publisher
    ..Here we show that the gut bacterium Bacteroides thetaiotaomicron uses the most structurally complex glycan known: the plant pectic polysaccharide rhamnogalacturonan-II, ..