Streptococcus iniae

Summary

Alias: Streptococcus iniae Pier and Madin 1976, Streptococcus shiloi, Streptococcus shiloi Eldar et al. 1995

Top Publications

  1. Gibello A, Collins M, Dom nguez L, Fern ndez Garayz bal J, Richardson P. Cloning and analysis of the L-lactate utilization genes from Streptococcus iniae. Appl Environ Microbiol. 1999;65:4346-50 pubmed
    ..A clone (pGR002) was isolated from a genomic library of Streptococcus iniae generated in Escherichia coli, containing a DNA fragment spanning two genes designated lctO and lctP...
  2. Fuller J, Camus A, Duncan C, Nizet V, Bast D, Thune R, et al. Identification of a streptolysin S-associated gene cluster and its role in the pathogenesis of Streptococcus iniae disease. Infect Immun. 2002;70:5730-9 pubmed
    b>Streptococcus iniae causes meningoencephalitis and death in cultured fish species and soft-tissue infection in humans. We recently reported that S...
  3. Locke J, Colvin K, Datta A, Patel S, Naidu N, Neely M, et al. Streptococcus iniae capsule impairs phagocytic clearance and contributes to virulence in fish. J Bacteriol. 2007;189:1279-87 pubmed
    ..Little is known about virulence mechanisms of the fish pathogen Streptococcus iniae, though indirect evidence suggests that capsule could represent an important factor. The putative S...
  4. Lowe B, Miller J, Neely M. Analysis of the polysaccharide capsule of the systemic pathogen Streptococcus iniae and its implications in virulence. Infect Immun. 2007;75:1255-64 pubmed
    ..To further define the virulence capacity of Streptococcus iniae, a zoonotic pathogen with the ability to cause severe systemic disease in both fish and humans, we ..
  5. Baiano J, Tumbol R, Umapathy A, Barnes A. Identification and molecular characterisation of a fibrinogen binding protein from Streptococcus iniae. BMC Microbiol. 2008;8:67 pubmed publisher
    ..This lack of diversity coupled with a functional role in macrophage resistance suggests that these proteins may constitute important targets for future vaccines against S. iniae in fish. ..
  6. Locke J, Aziz R, Vicknair M, Nizet V, Buchanan J. Streptococcus iniae M-like protein contributes to virulence in fish and is a target for live attenuated vaccine development. PLoS ONE. 2008;3:e2824 pubmed publisher
    b>Streptococcus iniae is a significant pathogen in finfish aquaculture, though knowledge of virulence determinants is lacking. Through pyrosequencing of the S...
  7. Cheng S, Hu Y, Jiao X, Sun L. Identification and immunoprotective analysis of a Streptococcus iniae subunit vaccine candidate. Vaccine. 2010;28:2636-41 pubmed publisher
    b>Streptococcus iniae is a Gram-positive bacterium and a severe aquaculture pathogen that can infect a wide range of farmed fish species...
  8. Umasuthan N, Bathige S, Revathy K, Nam B, Choi C, Lee J. Molecular genomic- and transcriptional-aspects of a teleost TRAF6 homolog: Possible involvement in immune responses of Oplegnathus fasciatus against pathogens. Fish Shellfish Immunol. 2015;42:66-78 pubmed publisher
    ..role of OfTRAF6 in response to flagellin, LPS, poly I:C, pathogenic bacteria (Edwardsiella tarda and Streptococcus iniae) and rock bream iridovirus (RBIV) was profiled in different tissues and OfTRAF6 revealed up-regulated ..
  9. Choi K, Shim S, An C, Nam B, Jeong J, Kim J, et al. Functional characterisation and expression analysis of recombinant serum amyloid P isoform 1 (RbSAP1) from rock bream (Oplegnathus fasciatus). Fish Shellfish Immunol. 2015;45:277-85 pubmed publisher
    ..expression was dramatically up-regulated in the kidney and liver after infection with Edwardsiella tarda, Streptococcus iniae, or red seabream iridovirus...

More Information

Publications128 found, 100 shown here

  1. Sellaththurai S, Priyathilaka T, Lee J. Molecular cloning, characterization, and expression level analysis of a marine teleost homolog of catalase from big belly seahorse (Hippocampus abdominalis). Fish Shellfish Immunol. 2019;89:647-659 pubmed publisher
    ..modulations of HaCat transcription were observed in blood, liver, and kidney tissues post-challenge with Streptococcus iniae, Edwardsiella tarda, poly I:C, and LPS...
  2. Godahewa G, Perera N, Kwon H, Lee J. Cloning and functional characterization of rockfish peroxiredoxin 4 homolog with its innate immune responses. Fish Shellfish Immunol. 2019;88:364-374 pubmed publisher
    ..observed in liver and spleen tissues of rockfish after injecting them with bacterial stimuli, including Streptococcus iniae, LPS, and a viral mimic of poly I:C...
  3. Oh M, Bathige S, Kim Y, Lee S, Yang H, Kim M, et al. A CXCL ortholog from Hippocampus abdominalis: Molecular features and functional delineation as a pro-inflammatory chemokine. Fish Shellfish Immunol. 2017;67:218-227 pubmed publisher
    ..of ShCXCL was observed in blood and kidney tissues after immune stimulation by live bacteria, such as Streptococcus iniae and Edwardsiella tarda, and mitogens, such as lipopolysaccharides (LPS) and polyinosinic:polycytidylic acid ..
  4. Choi K, Jeong J, Bae J, Cho D, Jung S, Hwang J, et al. Coagulation factor II from rock bream (Oplegnathus fasciatus): First report on the molecular biological function and expression analysis in the teleost. Fish Shellfish Immunol. 2016;48:145-53 pubmed publisher
    ..was dramatically up-regulated in the kidney, spleen and liver after infection with Edwardsiella tarda, Streptococcus iniae, or red seabream iridovirus...
  5. Thulasitha W, Whang I, Umasuthan N, Kang H, Mothishri M, Lee S, et al. A galectin related protein from Oplegnathus fasciatus: Genomic, molecular, transcriptional features and biological responses against microbial pathogens. Dev Comp Immunol. 2016;56:13-24 pubmed publisher
    ..like B) lacked carbohydrate-binding activity but was able to recognize and agglutinate bacteria, including Streptococcus iniae, Listeria monocytogenes, Vibrio tapetis, Escherichia coli, and Edwardsiella tarda, and a ciliate parasite, ..
  6. Umasuthan N, Bathige S, Noh J, Lee J. Gene structure, molecular characterization and transcriptional expression of two p38 isoforms (MAPK11 and MAPK14) from rock bream (Oplegnathus fasciatus). Fish Shellfish Immunol. 2015;47:331-43 pubmed publisher
    ..molecular patterns (PAMPs: flagellin, lipopolysaccharide and poly I:C) and pathogens (Edwardsiella tarda, Streptococcus iniae and rock bream iridovirus) was investigated...
  7. Cai X, Gao C, Song H, Yang N, Fu Q, Tan F, et al. Characterization, expression profiling and functional characterization of cathepsin Z (CTSZ) in turbot (Scophthalmus maximus L.). Fish Shellfish Immunol. 2019;84:599-608 pubmed publisher
    ..in intestine following both Gram-negative bacteria Vibrio anguillarum, and Gram-positive bacteria Streptococcus iniae immersion challenge...
  8. Kulatunga D, Dananjaya S, Nikapitiya C, Godahewa G, Cho J, Kim C, et al. Stress-immune responses and DNA protection function of thioredoxin domain containing 12 in zebrafish (Danio rerio). Fish Shellfish Immunol. 2019;84:1030-1040 pubmed publisher
    ..Moreover, transcriptional expression of Zftxndc12 was up-regulated upon Streptococcus iniae challenge in gills of adult zebrafish...
  9. Godahewa G, Bathige S, Herath H, Noh J, Lee J. Characterization of rock bream (Oplegnathus fasciatus) complement components C1r and C1s in terms of molecular aspects, genomic modulation, and immune responsive transcriptional profiles following bacterial and viral pathogen exposure. Fish Shellfish Immunol. 2015;46:656-68 pubmed publisher
    ..The putative roles of OfC1r and OfC1s in response to pathogenic bacteria (Edwardsiella tarda and Streptococcus iniae) and virus (rock bream iridovirus, RBIV) were investigated in liver and head kidney tissues...
  10. Umasuthan N, Bathige S, Whang I, Lim B, Choi C, Lee J. Insights into molecular profiles and genomic evolution of an IRAK4 homolog from rock bream (Oplegnathus fasciatus): immunogen- and pathogen-induced transcriptional expression. Fish Shellfish Immunol. 2015;43:436-48 pubmed publisher
    ..of animals challenged with potent immunogens (LPS and poly I:C) and pathogens (Edwardsiella tarda and Streptococcus iniae and rock bream iridovirus (RBIV))...
  11. Oh M, Umasuthan N, Elvitigala D, Wan Q, Jo E, Ko J, et al. First comparative characterization of three distinct ferritin subunits from a teleost: Evidence for immune-responsive mRNA expression and iron depriving activity of seahorse (Hippocampus abdominalis) ferritins. Fish Shellfish Immunol. 2016;49:450-60 pubmed publisher
    ..to be significantly modulated against pathogenic stress mounted by lipopolysaccharides (LPS), poly I:C, Streptococcus iniae, and Edwardsiella tarda...
  12. Jo E, Elvitigala D, Wan Q, Oh M, Oh C, Lee J. Identification and molecular profiling of DC-SIGN-like from big belly seahorse (Hippocampus abdominalis) inferring its potential relevancy in host immunity. Dev Comp Immunol. 2017;77:270-279 pubmed publisher
    ..in response to the stimulation of healthy fish with lipopolysaccharides (LPS), Edwardsiella tarda, or Streptococcus iniae. Moreover, recombinant ShDCS-like-CRD domain exhibited detectable agglutination activity against different ..
  13. Tharuka M, Bathige S, Lee J. Molecular cloning, biochemical characterization, and expression analysis of two glutathione S-transferase paralogs from the big-belly seahorse (Hippocampus abdominalis). Comp Biochem Physiol B Biochem Mol Biol. 2017;214:1-11 pubmed publisher
    ..Poly (I:C), and Edwardsiella tarda challenges in liver and in blood cells as well as with Streptococcus iniae challenge in blood cells...
  14. Godahewa G, Kim Y, Dananjaya S, Jayasooriya R, Noh J, Lee J, et al. Mitochondrial peroxiredoxin 3 (Prx3) from rock bream (Oplegnathus fasciatus): immune responses and role of recombinant Prx3 in protecting cells from hydrogen peroxide induced oxidative stress. Fish Shellfish Immunol. 2015;43:131-41 pubmed publisher
    ..Upon immune challenge of Edwardsiella tarda, Streptococcus iniae, rock bream iridovirus (RBIV) and lipopolysaccharide (LPS), RbPrx3 mRNA level was up-regulated in ..
  15. Lee W, Ahn G, Oh J, Kim S, Kang N, Kim E, et al. A prebiotic effect of Ecklonia cava on the growth and mortality of olive flounder infected with pathogenic bacteria. Fish Shellfish Immunol. 2016;51:313-320 pubmed publisher
    ..decreased the accumulative mortality of olive flounder infected by pathogenic bacteria (Edwardsiella tarda, Streptococcus iniae, and Vibrio harveyi). Overall, these results suggest that E...
  16. Jayasinghe J, Bathige S, Nam B, Noh J, Lee J. Comprehensive characterization of three glutathione S-transferase family proteins from black rockfish (Sebastes schlegelii). Comp Biochem Physiol C Toxicol Pharmacol. 2016;189:31-43 pubmed publisher
    ..The mRNA expression of RfGST? and RfGST?, upon Streptococcus iniae and poly I:C stimulation, revealed a significantly up-regulated expression, whereas RfGST? mRNA expression ..
  17. Neranjan Tharuka M, Bathige S, Oh M, Lee S, Kim M, Priyathilaka T, et al. Molecular characterization and expression analysis of big-belly seahorse (Hippocampus abdominalis) interleukin-10 and analysis of its potent anti-inflammatory properties in LPS-induced murine macrophage RAW 264.7 cells. Gene. 2019;685:1-11 pubmed publisher
    ..gill, and intestine upon in vivo induction with LPS, polyinosinic:polycytidylic acid [poly (I:C)], and Streptococcus iniae. To summarize, our findings help in the improved understanding of the biological functions of HaIL-10 and ..
  18. Elvitigala D, Priyathilaka T, Whang I, Nam B, Lee J. A teleostan homolog of catalase from black rockfish (Sebastes schlegelii): insights into functional roles in host antioxidant defense and expressional responses to septic conditions. Fish Shellfish Immunol. 2015;44:321-31 pubmed publisher
    ..In addition, RfCat mRNA expression was modulated in response to pathogenic stress elicited by Streptococcus iniae and poly I:C in blood and spleen tissues...
  19. Elvitigala D, Wan Q, Kim H, Lee J. Identification of a C-reactive protein like homologue from black rockfish (Sebastes schlegelii) evidencing its potent anti-microbial properties at molecular level. Dev Comp Immunol. 2015;53:169-78 pubmed publisher
    ..Moreover, recombinant RfCRP also exhibited anti-bacterial activity against both E. coli and Streptococcus iniae. In addition, qPCR analysis indicated that RfCRP is ubiquitously expressed in physiologically important ..
  20. Godahewa G, Perera N, Bathige S, Nam B, Noh J, Lee J. Complement factor D homolog involved in the alternative complement pathway of rock bream (Oplegnathus fasciatus): Molecular and functional characterization and immune responsive mRNA expression analysis. Fish Shellfish Immunol. 2016;55:423-33 pubmed publisher
    ..In addition, OfCfD transcripts were immunologically upregulated by lipopolysaccharide (LPS) (12 h p.i.), Streptococcus iniae (12 h p.i.), rock bream iridovirus (RBIV) (6-12 h p.i.), and poly I:C (6 h p.i.) in spleen tissue...
  21. Chen J, Zhang L, Yang N, Tian M, Fu Q, Tan F, et al. Expression profiling and microbial ligand binding analysis of galectin-4 in turbot (Scophthalmus maximus L.). Fish Shellfish Immunol. 2019;84:673-679 pubmed publisher
    ..in intestine following both Gram-negative bacteria Vibrio anguillarum, and Gram-positive bacteria Streptococcus iniae immersion challenge...
  22. Sun T, Zhan B, Gao Y. A novel cathelicidin from Bufo bufo gargarizans Cantor showed specific activity to its habitat bacteria. Gene. 2015;571:172-7 pubmed publisher
    ..and BG-CATH(5-37) had strong antimicrobial activities against aquatic bacteria of Vibrio splendidus, Streptococcus iniae and Aeromorus hydrophila, which were common microorganisms in the habitat of B. bufo gargarizans (MIC 3...
  23. Godahewa G, Perera N, Elvitigala D, Jayasooriya R, Kim G, Lee J. Characterization of a 1-cysteine peroxiredoxin from big-belly seahorse (Hippocampus abdominalis); insights into host antioxidant defense, molecular profiling and its expressional response to septic conditions. Fish Shellfish Immunol. 2016;57:186-197 pubmed publisher
    ..kidney tissues of fish after treating them with bacterial stimuli, including LPS, Edwardsiella tarda, and Streptococcus iniae. These results suggest that HaPrx6 may play an important role in the immune response of the big-belly ..
  24. Oh M, Elvitigala D, Bathige S, Lee S, Kim M, Lee J. Molecular and functional characterization of caspase-8 from the big-belly seahorse (Hippocampus abdominalis). Fish Shellfish Immunol. 2016;58:650-662 pubmed publisher
    ..mRNA level was found to be significantly modulated by lipopolysaccharide, polyinosinic:polycytidylic acid, Streptococcus iniae, and Edwardsiella tarda injection...
  25. Perera N, Godahewa G, Nam B, Park J, Lee J. Two metalloenzymes from rockfish (Sebastes schligellii): Deciphering their potential involvement in redox homeostasis against oxidative stress. Fish Shellfish Immunol. 2018;80:31-45 pubmed publisher
    ..illustrated the altered expression profiles of both RfCuZnSOD and RfMnSOD against lipopolysaccharide, Streptococcus iniae, and polyinosinic-polycytidylic acid (poly I:C)...
  26. Tian M, Yang N, Zhang L, Fu Q, Tan F, Li C. Expression profiling and functional characterization of galectin-3 of turbot (Scophthalmus maximus L.) in host mucosal immunity. Fish Shellfish Immunol. 2019;84:333-340 pubmed publisher
    ..in intestine following both Gram-negative bacteria Vibrio anguillarum, and Gram-positive bacteria Streptococcus iniae immersion challenge...
  27. Zou G, Nozaki R, Kondo H, Hirono I. Cloning and expression analysis of three novel CC chemokine genes from Japanese flounder (Paralichthys olivaceus). Fish Shellfish Immunol. 2014;40:507-13 pubmed publisher
    ..In response to infection by Gram-negative Edwardsiella tarda and Gram-positive Streptococcus iniae in kidney, only Paol-SCYA106 gene expression significantly increased...
  28. Godahewa G, Wickramaarachchi W, Whang I, Bathige S, Lim B, Choi C, et al. Two carboxypeptidase counterparts from rock bream (Oplegnathus fasciatus): molecular characterization, genomic arrangement and immune responses upon pathogenic stresses. Vet Immunol Immunopathol. 2014;162:180-91 pubmed publisher
    ..Both genes were transcriptionally regulated in the liver upon challenge with pathogenic bacteria (Streptococcus iniae, Edwardsiella tarda), rock bream iridovirus (RBIV), and the immune modulators polyinosinic:polycytidylic ..
  29. Herath H, Elvitigala D, Godahewa G, Umasuthan N, Whang I, Noh J, et al. Molecular characterization and comparative expression analysis of two teleostean pro-inflammatory cytokines, IL-1β and IL-8, from Sebastes schlegeli. Gene. 2016;575:732-42 pubmed publisher
    ..Two immune challenge experiments were conducted with Streptococcus iniae and polyinosinic:polycytidylic acid (poly I:C; a viral double stranded RNA mimic), and transcripts were ..
  30. Kim J, Jeong J, Bae J, Cho D, Jung S, Hwang J, et al. First description of programmed cell death10 (PDCD10) in rock bream (Oplegnathus fasciatus): Potential relations to the regulation of apoptosis by several pathogens. Dev Comp Immunol. 2016;55:51-5 pubmed publisher
    ..expression exhibited dramatic down-regulations in all of the examined tissues following injections of Streptococcus iniae, which is major bacterial pathogen that is responsible for mass mortality in rock bream...
  31. Kim J, Kong H, Nam B, Park J, Kim D, Jeong J, et al. The first report of cathepsin A gene in a teleost (rock bream, Oplegnathus fasciatus): An investigation of immune functions upon infection with several pathogens. Dev Comp Immunol. 2017;76:262-267 pubmed publisher
    ..In general, all of the examined tissues that were infected with Edwardsiella tarda, Streptococcus iniae, or red sea bream iridovirus (RSIV) exhibited significant upregulation of RbCTSA expression compared to the ..
  32. Priyathilaka T, Elvitigala D, Whang I, Lim B, Jeong H, Yeo S, et al. Molecular characterization and transcriptional analysis of non-mammalian type Toll like receptor (TLR21) from rock bream (Oplegnathus fasciatus). Gene. 2014;553:105-16 pubmed publisher
    ..Additionally, upon stimulation with Streptococcus iniae, rock bream iridovirus (RBIV), and Edwardsiella tarda, RbTLR21 mRNA was significantly up-regulated in ..
  33. Perera N, Godahewa G, Hwang J, Kwon M, Hwang S, Lee J. Molecular, structural, and functional comparison of N lobe and C lobe of the transferrin from rock bream, Oplegnathus fasciatus, with respect to its immune response. Fish Shellfish Immunol. 2017;68:299-309 pubmed publisher
    ..Temporal assessment revealed that RbTf increased after stimulation of LPS, Edwardsiella tarda, and Streptococcus iniae post injection (p.i.)...
  34. Kim J, Lee J, Bae J, An C, Nam B, Jeong J, et al. First molecular characterisation and expression analysis of a teleost thioredoxin-interacting protein (TXNIP) gene from rock bream (Oplegnathus fasciatus). Dev Comp Immunol. 2015;52:69-74 pubmed publisher
    ..Generally, all tissues examined from fish infected with Streptococcus iniae, Edwardsiella tarda and red sea bream iridovirus (RSIV) showed significant downregulation in RbTXNIP ..
  35. Godahewa G, Perera N, Lee J. Insights into the multifunctional role of natural killer enhancing factor-A (NKEF-A/Prx1) in big-belly seahorse (Hippocampus abdominalis): DNA protection, insulin reduction, H2O2 scavenging, and immune modulation activity. Gene. 2018;642:324-334 pubmed publisher
    ..immune response, HaNKEF-A transcripts were up-regulated in liver post injection of LPS, Edwardsiella tarda, Streptococcus iniae, and polyinosinic-polycytidylic acid...
  36. Gao C, Su B, Zhang D, Yang N, Song L, Fu Q, et al. l-rhamnose-binding lectins (RBLs) in turbot (Scophthalmus maximus L.): Characterization and expression profiling in mucosal tissues. Fish Shellfish Immunol. 2018;80:264-273 pubmed publisher
    ..Moreover, both RBLs were significantly up-regulated in mucosal tissues following V. anguillarum and Streptococcus iniae challenge, indicated their critical roles in turbot mucosal immunity...
  37. Kwon H, Yang H, Lee S, Nilojan J, Bathige S, Nam B, et al. Characterization of a Kazal-type serine protease inhibitor from black rockfish Sebastes schlegelii and its possible role in hepatic immune response. Fish Shellfish Immunol. 2018;74:485-490 pubmed publisher
    ..The SsKSPI mRNA expression was significantly up-regulated in response to both bacterial (Streptococcus iniae and lipopolysaccharide) and viral (polyinosinic:polycytidylic acid) challenges...
  38. Bathige S, Umasuthan N, Godahewa G, Jayasinghe J, Whang I, Noh J, et al. A homolog of Kunitz-type serine protease inhibitor from rock bream, Oplegnathus fasciatus: Molecular insights and transcriptional modulation in response to microbial and PAMP stimulation, and tissue injury. Fish Shellfish Immunol. 2015;46:285-91 pubmed publisher
    ..increased in blood cells upon stimulation with two strains of bacteria (Edwardsiella tarda and Streptococcus iniae) and two pathogen-associated molecular patterns (PAMPs; LPS and poly I:C)...
  39. Thanasaksiri K, Hirono I, Kondo H. Molecular cloning and expression analysis of NOD-like receptor 5 in Japanese flounder (Paralichthys olivaceus) after injection with two different formalin-killed pathogenic bacteria and poly (I:C). Dev Comp Immunol. 2017;67:481-484 pubmed publisher
    ..Expression of JfNLRC5 was up-regulated by formalin-killed Edwardsiella tarda but not by formalin-killed Streptococcus iniae. These findings suggest that JfNLRC5 is involved in fish immune response against viral and Gram-negative ..
  40. Cheng Z, Ma Y, Li H, Peng X. N-acetylglucosamine enhances survival ability of tilapias infected by Streptococcus iniae. Fish Shellfish Immunol. 2014;40:524-30 pubmed publisher
    b>Streptococcus iniae infection has emerged as a serious fish health and economic problem in the global aquaculture operations...
  41. Gabriel N, Qiang J, He J, Ma X, Kpundeh M, Xu P. Dietary Aloe vera supplementation on growth performance, some haemato-biochemical parameters and disease resistance against Streptococcus iniae in tilapia (GIFT). Fish Shellfish Immunol. 2015;44:504-14 pubmed publisher
    ..dietary Aloe vera on growth performance, some haemato-biochemical parameters and disease resistance against Streptococcus iniae in tilapia (GIFT). Five groups were designed including a basal diet (control) and 100% A...
  42. Ma Y, Yang M, Wang S, Li H, Peng X. Liver functional metabolomics discloses an action of L-leucine against Streptococcus iniae infection in tilapias. Fish Shellfish Immunol. 2015;45:414-21 pubmed publisher
    b>Streptococcus iniae seriously affects the intensive farming of tilapias. Much work has been conducted on prevention and control of S...
  43. Sun Y, Hu Y. Cell-penetrating peptide-mediated subunit vaccine generates a potent immune response and protection against Streptococcus iniae in Japanese flounder (Paralichthys olivaceus). Vet Immunol Immunopathol. 2015;167:96-103 pubmed publisher
    ..of transcription (TAT) peptides were fused to the N- or C-terminus of Sia10, a protective antigen of Streptococcus iniae, resulting in four recombinant fusion proteins, i.e., rAntp-Sia10, rSia10-Antp, rTAT-Sia10, and rSia10-TAT...
  44. Membrebe J, Yoon N, Hong M, Lee J, Lee H, Park K, et al. Protective efficacy of Streptococcus iniae derived enolase against Streptococcal infection in a zebrafish model. Vet Immunol Immunopathol. 2016;170:25-9 pubmed publisher
    Enolase (ENO) is one of the surface-exposed proteins of Streptococcus iniae, which previously had been identified as a plasminogen-binding protein. In this study, ENO was evaluated to induce cross-protective immunity against S...
  45. Dong X, Su B, Zhou S, Shang M, Yan H, Liu F, et al. Identification and expression analysis of toll-like receptor genes (TLR8 and TLR9) in mucosal tissues of turbot (Scophthalmus maximus L.) following bacterial challenge. Fish Shellfish Immunol. 2016;58:309-317 pubmed publisher
    ..comparatively observed in the mucosal tissues (intestine, gill and skin) following Vibrio anguillarum and Streptococcus iniae infection, suggesting their different roles for mucosal immunity...
  46. Yamamoto F, Yin F, Rossi W, Hume M, Gatlin D. ?-1,3 glucan derived from Euglena gracilis and Algamune™ enhances innate immune responses of red drum (Sciaenops ocellatus L.). Fish Shellfish Immunol. 2018;77:273-279 pubmed publisher
    ..Increased bactericidal activity against Streptococcus iniae, and production of intracellular O2- anion superoxide were stimulated by both ?-..
  47. Zheng Z, Xu W, Aweya J, Zhong M, Liu S, Lun J, et al. Functional domains of Litopenaeus vannamei transglutaminase and their involvement in immunoregulation in shrimp. Fish Shellfish Immunol. 2018;81:168-175 pubmed publisher
    ..functional domains, as it had higher bacterial agglutinative activity against Vibrio parahaemolyticus and Streptococcus iniae. Using Co-immunoprecipitation and LC-MS/MS analysis, TGase-C was shown to interact with 474 proteins, of ..
  48. Ran C, Carrias A, Williams M, Capps N, Dan B, Newton J, et al. Identification of Bacillus strains for biological control of catfish pathogens. PLoS ONE. 2012;7:e45793 pubmed publisher
    ..expressed antagonistic activity against multiple aquatic bacterial pathogens including Edwardsiella tarda, Streptococcus iniae, Yersinia ruckeri, Flavobacterium columnare, and/or the oomycete Saprolegnia ferax...
  49. Woo S, Park S. Effects of phosphoglucomutase gene (PGM) in Streptococcus parauberis on innate immune response and pathogenicity of olive flounder (Paralichthys olivaceus). Fish Shellfish Immunol. 2014;41:317-25 pubmed publisher
    ..in South Korea because of its more frequent isolation than other streptococcal bacteria including Streptococcus iniae. To develop effective treatment and prophylaxis methods against this emerging disease by S...
  50. Beck B, Kim D, Jeon J, Lee S, Kim H, Kim O, et al. The effects of combined dietary probiotics Lactococcus lactis BFE920 and Lactobacillus plantarum FGL0001 on innate immunity and disease resistance in olive flounder (Paralichthys olivaceus). Fish Shellfish Immunol. 2015;42:177-83 pubmed publisher
    ..p. injection of Streptococcus iniae (log10 6.0 CFU/fish). The groups fed the mixed probiotics, Lc. lactis BFE920, Lb...
  51. Iwashita M, Nakandakare I, Terhune J, Wood T, Ranzani Paiva M. Dietary supplementation with Bacillus subtilis, Saccharomyces cerevisiae and Aspergillus oryzae enhance immunity and disease resistance against Aeromonas hydrophila and Streptococcus iniae infection in juvenile tilapia Oreochromis niloticus. Fish Shellfish Immunol. 2015;43:60-6 pubmed publisher
    ..microbiology and challenged by intraperitoneal injection of LD50 concentration of Aeromonas hydrophila and Streptococcus iniae. Mortality was recorded for the following 3 weeks...
  52. Umasuthan N, Mothishri M, Thulasitha W, Nam B, Lee J. Molecular, genomic, and expressional delineation of a piscidin from rock bream (Oplegnathus fasciatus) with evidence for the potent antimicrobial activities of Of-Pis1 peptide. Fish Shellfish Immunol. 2016;48:154-68 pubmed publisher
    ..LPS); polyinosinic:polycytidylic acid (poly I:C); and pathogens, including Edwardsiella tarda, Streptococcus iniae, and rock bream iridovirus (RBIV), was weak...
  53. Wang E, Wang J, Long B, Wang K, He Y, Yang Q, et al. Molecular cloning, expression and the adjuvant effects of interleukin-8 of channel catfish (Ictalurus Punctatus) against Streptococcus iniae. Sci Rep. 2016;6:29310 pubmed publisher
    ..evaluated for its adjuvant effects on the immunoprotection of subunit vaccine encoding ?-enolase (rENO) of Streptococcus iniae from several aspects in channel catfish...
  54. Kim S, Nho S, Im S, Lee J, Jung J, Lazarte J, et al. Rapid MALDI biotyper-based identification and cluster analysis of Streptococcus iniae. J Microbiol. 2017;55:260-266 pubmed publisher
    b>Streptococcus iniae causes severe mortalities among cultured marine species, especially in the olive flounder (Paralichthys olivaceus), which is economically important in Korea and Japan...
  55. Heath C, Gillen C, Chrysanthopoulos P, Walker M, Barnes A. Streptococcus iniae cpsG alters capsular carbohydrate composition and is a cause of serotype switching in vaccinated fish. Vet Microbiol. 2016;193:116-24 pubmed publisher
    b>Streptococcus iniae causes septicaemia and meningitis in marine and freshwater fish wherever they are farmed in warm-temperate and tropical regions...
  56. Harvie E, Huttenlocher A. Non-invasive Imaging of the Innate Immune Response in a Zebrafish Larval Model of Streptococcus iniae Infection. J Vis Exp. 2015;: pubmed publisher
    The aquatic pathogen, Streptococcus iniae, is responsible for over 100 million dollars in annual losses for the aquaculture industry and is capable of causing systemic disease in both fish and humans. A better understanding of S...
  57. Elvitigala D, Whang I, Jung H, Lim B, Nam B, Lee J. Molecular delineation of a caspase 10 homolog from black rockfish (Sebastes schlegelii) and its transcriptional regulation in response to pathogenic stress. Gene. 2015;570:288-94 pubmed publisher
    ..conditions, whereas its expression was found to be upregulated under pathogenic stress, elicited by Streptococcus iniae and polyinosinic:polycytidylic acid in blood, liver, and spleen tissues...
  58. Liu F, Su B, Fu Q, Shang M, Gao C, Tan F, et al. Identification, characterization and expression analysis of TLR5 in the mucosal tissues of turbot (Scophthalmus maximus L.) following bacterial challenge. Fish Shellfish Immunol. 2017;68:272-279 pubmed publisher
    ..After Streptococcus iniae infection, the TLR5a was down-regulated at 2 h while generally up-regulated after 4 h in mucosal tissues...
  59. Perez Casal J, Potter A. Glyceradehyde-3-phosphate dehydrogenase as a suitable vaccine candidate for protection against bacterial and parasitic diseases. Vaccine. 2016;34:1012-7 pubmed publisher
    ..Vibrio spp., Edwarsiella spp., and Streptococcus iniae; and environmental streptococci, namely, Streptococcus uberis and Streptococcus dysgalactiae...
  60. Cefalo A, Broadbent J, Welker D. Intraspecific and interspecific interactions among proteins regulating exopolysaccharide synthesis in Streptococcus thermophilus, Streptococcus iniae, and Lactococcus lactis subsp. cremoris and the assessment of potential lateral gene transfer. Can J Microbiol. 2011;57:1002-15 pubmed publisher
    Using the yeast two-hybrid system, intraspecific protein interactions were detected in Streptococcus iniae and Lactococcus lactis subsp...
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    ..Immune challenges with live bacteria (Edwardsiella tarda and Streptococcus iniae), rock bream irido virus, and mitogens (lipopolysaccharide and poly I:C) modulated the expression of OfGal-..
  62. Choi K, Joo M, Cho D, Bae J, Jeong J, Woo W, et al. Molecular characterization, expression and functional analysis of peptidoglycan recognition protein-SC2 from rock bream, Oplegnathus fasciatus. Fish Shellfish Immunol. 2018;77:286-293 pubmed publisher
    ..After challenge with microbial pathogens (Edwardsiella piscicida), Streptococcus iniae or red seabream iridovirus [RSIV]), RbPGRP-SC2 was up-regulated in all the tissues examined, especially in ..
  63. Safari R, Adel M, Lazado C, Caipang C, Dadar M. Host-derived probiotics Enterococcus casseliflavus improves resistance against Streptococcus iniae infection in rainbow trout (Oncorhynchus mykiss) via immunomodulation. Fish Shellfish Immunol. 2016;52:198-205 pubmed publisher
    ..Challenge test showed that probiotic feeding significantly improved host resistance to Streptococcus iniae infection, specifically in T2 and T3 where a considerable modulation of immune responses was observed...
  64. Hoseinifar S, Mirvaghefi A, Amoozegar M, Sharifian M, Esteban M. Modulation of innate immune response, mucosal parameters and disease resistance in rainbow trout (Oncorhynchus mykiss) upon synbiotic feeding. Fish Shellfish Immunol. 2015;45:27-32 pubmed publisher
    ..burst activities) and skin mucus parameters (bactericidal activity against Streptococcus faecium, Streptococcus iniae, Serratia marcescens, Staphylococcus aureus and Escherichia coli and mucus protein content) were studied...
  65. Han B, Long W, He J, Liu Y, Si Y, Tian L. Effects of dietary Bacillus licheniformis on growth performance, immunological parameters, intestinal morphology and resistance of juvenile Nile tilapia (Oreochromis niloticus) to challenge infections. Fish Shellfish Immunol. 2015;46:225-31 pubmed publisher
    ..licheniformis supplementation (P > 0.05). When tilapia were challenged against Streptococcus iniae, survival rate improved significantly when tilapia fed with T2, T3, T4 and T5 (P < 0.05)...
  66. Hwang S, Bae J, Jo D, Kim K, Cho M, Jee B, et al. Gene expression and functional characterization of serum amyloid P component 2 in rock bream, Oplegnathus fasciatus. Fish Shellfish Immunol. 2015;47:521-7 pubmed publisher
    ..A high concentration of recombinant RbSAP2 (rRbSAP2) showed lower growth Streptococcus iniae than control in the absence of Ca(2+), whereas E...
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    ..Prompt transcription of SsPrx5 was shown in the immune-stimulated gill and liver tissues against Streptococcus iniae and lipopolysaccharide injection...
  68. Rajoo S, Jeon W, Park K, Yoo S, Yoon I, Lee H, et al. Complete Genome Sequence of Streptococcus iniae YSFST01-82, Isolated from Olive Flounder in Jeju, South Korea. Genome Announc. 2015;3: pubmed publisher
    b>Streptococcus iniae is associated with morbidity in commercial fish species, especially in olive flounders (Paralichthys olivaceus), and was recently identified as an emerging human pathogen. Here, we report the complete 2...
  69. Cerqueira M, Rey S, Silva T, Featherstone Z, Crumlish M, MacKenzie S. Thermal preference predicts animal personality in Nile tilapia Oreochromis niloticus. J Anim Ecol. 2016;85:1389-400 pubmed publisher
    ..Additionally, fish were then challenged using a bacterial Streptococcus iniae model infection to assess the behavioural fever response of proactive and reactive fish...
  70. El Aamri F, Real F, Acosta F, Bravo J, Román L, Déniz S, et al. Differential innate immune response of European seabass (Dicentrarchus labrax) against Streptococcus iniae. Fish Shellfish Immunol. 2015;46:436-41 pubmed publisher
    b>Streptococcus iniae is a Gram-positive bacteria that causes invasive infections with severe septicemia and meningitis, producing high economic losses in marine and continental aquaculture...
  71. Jiang J, Zheng Z, Wang K, Wang J, He Y, Wang E, et al. Adjuvant Immune Enhancement of Subunit Vaccine Encoding pSCPI of Streptococcus iniae in Channel Catfish (Ictalurus punctatus). Int J Mol Sci. 2015;16:28001-13 pubmed publisher
    Channel catfish (Ictalurus punctatus) is an important agricultural fish that has been plagued by Streptococcus iniae (S. iniae) infections in recent years, some of them severe. C5a peptidase is an important virulent factor of S. iniae...
  72. Vilas Boas L, Headley S, Gonçalves K, Scarpassa J, Pretto Giordano L. Complete Genome Sequence of Streptococcus iniae UEL-Si1, Isolated in Diseased Nile Tilapia (Oreochromis niloticus) from Northern Paraná, Southern Brazil. Genome Announc. 2017;5: pubmed publisher
    The Streptococcus iniae UEL-Si1 strain was isolated from diseased Nile tilapia within the Paranapanema River Basin, Northern Paraná, Brazil...
  73. Xie S, Zhou W, Tian L, Niu J, Liu Y. Effect of N-acetyl cysteine and glycine supplementation on growth performance, glutathione synthesis, anti-oxidative and immune ability of Nile tilapia, Oreochromis niloticus. Fish Shellfish Immunol. 2016;55:233-41 pubmed publisher
    ..After the feeding trail, fish were challenged by Streptococcus iniae, fish fed the diet supplemented with NAC obtained significantly higher survival rate after 72 h challenge ..
  74. Gong H, Wu S, Chen C, Huang C, Lu J, Chou H. Complete Genome Sequence of Streptococcus iniae 89353, a Virulent Strain Isolated from Diseased Tilapia in Taiwan. Genome Announc. 2017;5: pubmed publisher
    b>Streptococcus iniae 89353 is a virulent strain isolated from diseased tilapia in Taiwan. The full-genome sequence of S. iniae 89353 is 2,098,647 bp...
  75. Bathige S, Thulasitha W, Umasuthan N, Jayasinghe J, Wan Q, Nam B, et al. A homolog of teleostean signal transducer and activator of transcription 3 (STAT3) from rock bream, Oplegnathus fasciatus: Structural insights, transcriptional modulation, and subcellular localization. Vet Immunol Immunopathol. 2017;186:29-40 pubmed publisher
    ..of RbSTAT3 was examined in blood and liver tissues after challenges with bacteria (Edwardsiella tarda and Streptococcus iniae), rock bream irido virus (RBIV), and immune stimulants (LPS and poly (I:C))...
  76. Bathige S, Umasuthan N, Priyathilaka T, Thulasitha W, Jayasinghe J, Wan Q, et al. Molecular cloning, transcriptional profiling, and subcellular localization of signal transducer and activator of transcription 2 (STAT2) ortholog from rock bream, Oplegnathus fasciatus. Gene. 2017;626:95-105 pubmed publisher
    ..immune challenge experiments with viral (rock bream irido virus; RBIV), bacterial (Edwardsiella tarda and Streptococcus iniae), and immune stimulants (poly I:C and LPS)...
  77. Zhang L, Gao C, Liu F, Song L, Su B, Li C. Characterization and expression analysis of a peptidoglycan recognition protein gene, SmPGRP2 in mucosal tissues of turbot (Scophthalmus maximus L.) following bacterial challenge. Fish Shellfish Immunol. 2016;56:367-373 pubmed publisher
    ..and investigated its expression patterns in mucosal tissues after challenge with Gram-positive bacteria Streptococcus iniae and Gram-negative bacteria Vibrio anguillarum...
  78. Adel M, Yeganeh S, Dadar M, Sakai M, Dawood M. Effects of dietary Spirulina platensis on growth performance, humoral and mucosal immune responses and disease resistance in juvenile great sturgeon (Huso huso Linnaeus, 1754). Fish Shellfish Immunol. 2016;56:436-444 pubmed publisher
    ..Total proteins, lysozyme, protease and esterase, as well as in vitro bactericidal activity (against Streptococcus iniae, Yersinia ruckeri, Aeromonas hydrophila and Lactococcus garviea) were significantly high in skin mucus from ..
  79. Soto E, Richey C, Stevens B, Yun S, Kenelty K, Reichley S, et al. Co-infection of Acipenserid herpesvirus 2 (AciHV-2) and Streptococcus iniae in cultured white sturgeon Acipenser transmontanus. Dis Aquat Organ. 2017;124:11-20 pubmed publisher
    ..In addition, Streptococcus iniae was recovered from internal organs of affected fish...
  80. Haines A, Nebergall E, Besong E, Council K, Lambert O, Gauthier D. Draft Genome Sequences for Seven Streptococcus parauberis Isolates from Wild Fish in the Chesapeake Bay. Genome Announc. 2016;4: pubmed publisher
    Streptococcus parauberis is a pathogen of cattle and fish, closely related Streptococcus uberis and Streptococcus iniae We report the genomes of seven S...
  81. Song Z, Yue R, Sun Y, Liu C, Khan S, Li C, et al. Fatal bacterial septicemia in a bottlenose dolphin Tursiops truncatus caused by Streptococcus iniae. Dis Aquat Organ. 2017;122:195-203 pubmed publisher
    ..The isolate was identified by 16S rDNA sequencing as Streptococcus iniae. Histological examination of the digestive system revealed a mixed infection of both bacteria and fungus...
  82. Lee W, Oh J, Kim E, Kang N, Kim K, Ahn G, et al. A prebiotic role of Ecklonia cava improves the mortality of Edwardsiella tarda-infected zebrafish models via regulating the growth of lactic acid bacteria and pathogen bacteria. Fish Shellfish Immunol. 2016;54:620-8 pubmed publisher
    ..tarda, Streptococcus iniae; S. iniae, and Vibrio harveyi; V. harveyi)...
  83. Kim D, Beck B, Lee S, Jeon J, Lee D, Lee J, et al. Pellet feed adsorbed with the recombinant Lactococcus lactis BFE920 expressing SiMA antigen induced strong recall vaccine effects against Streptococcus iniae infection in olive flounder (Paralichthys olivaceus). Fish Shellfish Immunol. 2016;55:374-83 pubmed publisher
    ..bacterium (LAB), Lactococcus lactis BFE920, was modified to express the SiMA antigen, a membrane protein of Streptococcus iniae. The antigen was engineered to be expressed under the nisin promoter, which is induced by nisin produced ..
  84. Vega L, Valdes K, Sundar G, Belew A, Islam E, Berge J, et al. The Transcriptional Regulator CpsY Is Important for Innate Immune Evasion in Streptococcus pyogenes. Infect Immun. 2017;85: pubmed publisher
    ..CpsY is homologous with transcriptional regulators of Streptococcus mutans (MetR), Streptococcus iniae (CpsY), and Streptococcus agalactiae (MtaR) that regulate methionine transport, amino acid ..
  85. El Aamri F, Guillén J, Padilla D, Bravo J, Vega B, Acosta F, et al. Identification of some main Streptococcus iniae associated proteins: relationship. Vet Res Commun. 2017;41:85-95 pubmed publisher
    ..To study differences at the genomic level, we first sequenced the whole genome of Streptococcus iniae from fish (IUSA-1 strain) and compared it to Streptococcus iniae from human (9117 strain), revealing a high ..
  86. Qiang J, Tao Y, He J, Li H, Xu P, Bao J, et al. Inhibition of miR-92d-3p enhances inflammation responses in genetically improved farmed tilapia (GIFT, Oreochromis niloticus) with Streptococcus iniae infection by modulating complement C3. Fish Shellfish Immunol. 2017;63:367-375 pubmed publisher
    ..previously in head kidney of genetically improved farmed tilapia (GIFT, Oreochromis niloticus) exposed to Streptococcus iniae infection...
  87. Gao C, Cai X, Zhang Y, Su B, Song H, Wenqi W, et al. Characterization and expression analysis of chitinase genes (CHIT1, CHIT2 and CHIT3) in turbot (Scophthalmus maximus L.) following bacterial challenge. Fish Shellfish Immunol. 2017;64:357-366 pubmed publisher
    ..of turbot and characterized their expression patterns in mucosal tissues following Vibrio anguillarum and Streptococcus iniae challenge...
  88. Lim J, Jung M, Jung S, Kim D, Park K, Kang S. The efficacy of amoxicillin sodium against streptococcosis in cultured olive flounder Paralichthys olivaceus and its pharmacokinetics. J Vet Pharmacol Ther. 2017;40:77-87 pubmed publisher
    The efficacy of amoxicillin sodium for controlling field and experimental Streptococcus iniae and S. parauberis infections in olive flounder (Paralichthys olivaceus) was evaluated after a single intramuscular administration...
  89. Pourgholam M, Khara H, Safari R, Sadati M, Aramli M. Hemato-Immunological Responses and Disease Resistance in Siberian Sturgeon Acipenser baerii Fed on a Supplemented Diet of Lactobacillus plantarum. Probiotics Antimicrob Proteins. 2017;9:32-40 pubmed publisher
    ..levels of dietary Lactobacillus plantarum on hemato-immunological parameters and resistance against Streptococcus iniae infection in juvenile Siberian sturgeon Acipenser baerii. Fish (14.6 ± 2...
  90. Qiang J, Tao F, He J, Sun L, Xu P, Bao W. Effects of exposure to Streptococcus iniae on microRNA expression in the head kidney of genetically improved farmed tilapia (Oreochromis niloticus). BMC Genomics. 2017;18:190 pubmed publisher
    Genetically improved farmed tilapia (GIFT, Oreochromis niloticus) are susceptible to infection by Streptococcus iniae when maintained in modern intensive culture systems...
  91. Pavithiran A, Bathige S, Kugapreethan R, Priyathilaka T, Yang H, Kim M, et al. A comparative study of three akirin genes from big belly seahorse Hippocampus abdominalis: Molecular, transcriptional and functional characterization. Fish Shellfish Immunol. 2018;74:584-592 pubmed publisher
    ..Immune challenge with LPS, poly I:C, and Streptococcus iniae exhibited a significant increase in the expression of all three HaAkirins in kidney and liver tissues...
  92. Thulasitha W, Kim Y, Umasuthan N, Jayasooriya R, Kim G, Nam B, et al. Thioredoxin domain-containing protein 12 from Oplegnathus fasciatus: Molecular characterization, expression against immune stimuli, and biological activities related to oxidative stress. Fish Shellfish Immunol. 2016;54:11-21 pubmed publisher
    ..In comparison, injection of lipopolysaccharide, Edwardsiella tarda, Streptococcus iniae, polyinosinic:polycytidylic acid (poly[I:C]) and rock bream iridovirus mostly triggered greater ..