Listeria monocytogenes EGD-e

Summary

Alias: Listeria monocytogenes ATCC BAA-679, Listeria monocytogenes EGDe, Listeria monocytogenes str. EGD-e, Listeria monocytogenes strain EGD-e

Top Publications

  1. Khelef N, Lecuit M, Bierne H, Cossart P. Species specificity of the Listeria monocytogenes InlB protein. Cell Microbiol. 2006;8:457-70 pubmed
    ..These results unravel a second L. monocytogenes species specificity critical for understanding human listeriosis and emphasize the need for developing new animal models for studying InlA and InlB functions in the same animal model. ..
  2. Dons L, Rasmussen O, Olsen J. Cloning and characterization of a gene encoding flagellin of Listeria monocytogenes. Mol Microbiol. 1992;6:2919-29 pubmed
    ..monocytogenes can be divided into two groups. These groups correspond to the flagellar antigens AB and ABC, respectively, as well as to the two types of L. monocytogenes based on the DNA sequence of the listeriolysin gene. ..
  3. McLaughlan A, Foster S. Molecular characterization of an autolytic amidase of Listeria monocytogenes EGD. Microbiology. 1998;144 ( Pt 5):1359-67 pubmed
    ..Characterization of the recombinant enzyme expressed in Escherichia coli has revealed it to be an amidase and to be able to hydrolyse a range of peptidoglycan substrates. ..
  4. Wiedmann M, Arvik T, Hurley R, Boor K. General stress transcription factor sigmaB and its role in acid tolerance and virulence of Listeria monocytogenes. J Bacteriol. 1998;180:3650-6 pubmed
    ..Our results suggest that sigmaB-directed genes do not appear to be essential for the spread of L. monocytogenes to mouse liver or spleen at 2 and 4 days following intragastric or intraperitoneal infection. ..
  5. Gahan C, O Mahony J, Hill C. Characterization of the groESL operon in Listeria monocytogenes: utilization of two reporter systems (gfp and hly) for evaluating in vivo expression. Infect Immun. 2001;69:3924-32 pubmed
    ..In this strain hemolysin expression during infection also confirms transcription from the groESL promoter during J774 and murine infection, albeit at lower levels than the known virulence factor plcA. ..
  6. Abachin E, Poyart C, Pellegrini E, Milohanic E, Fiedler F, Berche P, et al. Formation of D-alanyl-lipoteichoic acid is required for adhesion and virulence of Listeria monocytogenes. Mol Microbiol. 2002;43:1-14 pubmed
    ..These results show that the D-alanylation of the LTAs contributes to the virulence of the intracellular pathogen L. monocytogenes. ..
  7. Liu S, Graham J, Bigelow L, Morse P, Wilkinson B. Identification of Listeria monocytogenes genes expressed in response to growth at low temperature. Appl Environ Microbiol. 2002;68:1697-705 pubmed
  8. Schubert W, Urbanke C, Ziehm T, Beier V, Machner M, Domann E, et al. Structure of internalin, a major invasion protein of Listeria monocytogenes, in complex with its human receptor E-cadherin. Cell. 2002;111:825-36 pubmed
    ..monocytogenes infection that is essential for intermolecular recognition. Our studies reveal the structural basis for host tro-pism of this bacterium and the molecular deception L. monocytogenes employs to exploit the E-cadherin system. ..
  9. Kallipolitis B, Ingmer H, Gahan C, Hill C, Søgaard Andersen L. CesRK, a two-component signal transduction system in Listeria monocytogenes, responds to the presence of cell wall-acting antibiotics and affects beta-lactam resistance. Antimicrob Agents Chemother. 2003;47:3421-9 pubmed
    ..These results further our understanding of how L. monocytogenes senses and responds to antibiotics that are used therapeutically in the treatment of infectious diseases. ..

More Information

Publications132 found, 100 shown here

  1. GRUNDLING A, Burrack L, Bouwer H, Higgins D. Listeria monocytogenes regulates flagellar motility gene expression through MogR, a transcriptional repressor required for virulence. Proc Natl Acad Sci U S A. 2004;101:12318-23 pubmed
    ..These studies indicate that regulation of flagellar motility gene expression and/or other genes controlled by MogR is required for full virulence of L. monocytogenes. ..
  2. Olsen K, Larsen M, Gahan C, Kallipolitis B, Wolf X, Rea R, et al. The Dps-like protein Fri of Listeria monocytogenes promotes stress tolerance and intracellular multiplication in macrophage-like cells. Microbiology. 2005;151:925-33 pubmed
    ..A1 mouse macrophage cells. Thus, the data suggest that Fri contributes to the ability of L. monocytogenes to survive in environments where oxidative stress and low iron availability may impede bacterial proliferation. ..
  3. Machata S, Hain T, Rohde M, Chakraborty T. Simultaneous deficiency of both MurA and p60 proteins generates a rough phenotype in Listeria monocytogenes. J Bacteriol. 2005;187:8385-94 pubmed
    ..monocytogenes. We also identified homologous MurA and SecA2 proteins in other Listeria species. The muramidase in two species, L. innocua and L. welshimeri, shows activity similar to that of the MurA protein in L. monocytogenes. ..
  4. Rieu A, Weidmann S, Garmyn D, Piveteau P, Guzzo J. Agr system of Listeria monocytogenes EGD-e: role in adherence and differential expression pattern. Appl Environ Microbiol. 2007;73:6125-33 pubmed
  5. Wollert T, Heinz D, Schubert W. Thermodynamically reengineering the listerial invasion complex InlA/E-cadherin. Proc Natl Acad Sci U S A. 2007;104:13960-5 pubmed
    ..One such pair of single substitutions improves affinity 5,000-fold. We thus demonstrate that rational reengineering of protein complexes is possible by making use of physically distant hot spots of recognition. ..
  6. Gueriri I, Cyncynatus C, Dubrac S, Arana A, Dussurget O, Msadek T. The DegU orphan response regulator of Listeria monocytogenes autorepresses its own synthesis and is required for bacterial motility, virulence and biofilm formation. Microbiology. 2008;154:2251-64 pubmed publisher
    ..Taken together, our results indicate that despite the lack of the DegS kinase, DegU is fully functional as an orphan response regulator, and plays a central role in controlling several crucial adaptive responses in L. monocytogenes. ..
  7. Gaillard J, Berche P, Frehel C, Gouin E, Cossart P. Entry of L. monocytogenes into cells is mediated by internalin, a repeat protein reminiscent of surface antigens from gram-positive cocci. Cell. 1991;65:1127-41 pubmed
    ..As evidenced by Southern blot analysis, inlA is part of a gene family. One of them is the gene situated directly downstream of inlA, called inlB, which also encodes a leucine-rich repeat protein. ..
  8. Leimeister Wächter M, Haffner C, Domann E, Goebel W, Chakraborty T. Identification of a gene that positively regulates expression of listeriolysin, the major virulence factor of listeria monocytogenes. Proc Natl Acad Sci U S A. 1990;87:8336-40 pubmed
    ..monocytogenes strain EGD. We have designated the gene encoding the 27-kDa polypeptide prfA, for positive regulatory factor of listeriolysin (lisA) expression. The prfA gene regulates transcription of the lisA gene positively. ..
  9. Dons L, Olsen J, Rasmussen O. Characterization of two putative Listeria monocytogenes genes encoding polypeptides homologous to the sensor protein CheA and the response regulator CheY of chemotaxis. DNA Seq. 1994;4:301-11 pubmed
    ..monocytogenes and consequently the putative genes are named cheY and cheA. Northern blot and primer extension analysis suggested that cheY and cheA are transcribed as a bicistronic unit and that the transcription is thermoregulated. ..
  10. Lenz L, Dere B, Bevan M. Identification of an H2-M3-restricted Listeria epitope: implications for antigen presentation by M3. Immunity. 1996;5:63-72 pubmed
  11. Braun L, Dramsi S, Dehoux P, Bierne H, Lindahl G, Cossart P. InlB: an invasion protein of Listeria monocytogenes with a novel type of surface association. Mol Microbiol. 1997;25:285-94 pubmed
    ..This motif may have important consequences for the release of surface proteins involved in interactions with eukaryotic cells. ..
  12. Becker L, Cetin M, Hutkins R, Benson A. Identification of the gene encoding the alternative sigma factor sigmaB from Listeria monocytogenes and its role in osmotolerance. J Bacteriol. 1998;180:4547-54 pubmed
    ..Thus, sigmaB coordinates responses to a variety of physical and chemical signals, and its function facilitates the growth of L. monocytogenes under conditions of high osmotic strength. ..
  13. Knudsen G, Olsen J, Dons L. Characterization of DegU, a response regulator in Listeria monocytogenes, involved in regulation of motility and contributes to virulence. FEMS Microbiol Lett. 2004;240:171-9 pubmed
    ..The results indicate that the putative DegU response regulator is a pleiotropic regulator involved in expression of both motility at low temperature and in vivo virulence in mice. ..
  14. Stack H, Sleator R, Bowers M, Hill C, Gahan C. Role for HtrA in stress induction and virulence potential in Listeria monocytogenes. Appl Environ Microbiol. 2005;71:4241-7 pubmed
    ..Our findings suggest that L. monocytogenes lmo0292 encodes an HtrA-like serine protease that is not part of the classical heat shock response but is involved in stress responses and virulence. ..
  15. Dussurget O, Dumas E, Archambaud C, Chafsey I, Chambon C, Hebraud M, et al. Listeria monocytogenes ferritin protects against multiple stresses and is required for virulence. FEMS Microbiol Lett. 2005;250:253-61 pubmed
    ..A comparative proteomic analysis revealed an effect of the fri deletion on the levels of listeriolysin O and several stress proteins. Together, our study demonstrates that fri has multiple roles that contribute to Listeria virulence. ..
  16. Begley M, Hill C, Ross R. Tolerance of Listeria monocytogenes to cell envelope-acting antimicrobial agents is dependent on SigB. Appl Environ Microbiol. 2006;72:2231-4 pubmed
    ..SigB may therefore represent an attractive target for the development of new control and treatment strategies for this important pathogen. ..
  17. Dubail I, Bigot A, Lazarevic V, Soldo B, Euphrasie D, Dupuis M, et al. Identification of an essential gene of Listeria monocytogenes involved in teichoic acid biogenesis. J Bacteriol. 2006;188:6580-91 pubmed
    ..monocytogenes that is involved in teichoic acid biogenesis. In vivo, the conditional mutant is very rapidly eliminated from the target organs of infected mice and thus is totally avirulent. ..
  18. Personnic N, Bruck S, Nahori M, Toledo Arana A, Nikitas G, Lecuit M, et al. The stress-induced virulence protein InlH controls interleukin-6 production during murine listeriosis. Infect Immun. 2010;78:1979-89 pubmed publisher
    ..These results strongly suggest that InlH is a stress-induced surface protein that facilitates pathogen survival in tissues by tempering the inflammatory response. ..
  19. Korsak D, Markiewicz Z, Gutkind G, Ayala J. Identification of the full set of Listeria monocytogenes penicillin-binding proteins and characterization of PBPD2 (Lmo2812). BMC Microbiol. 2010;10:239 pubmed publisher
    ..Since Lmo2812 preferentially degrades low-molecular- mass substrates, this may indicate a role in cell wall turnover. ..
  20. Garcia del Portillo F, Calvo E, D Orazio V, Pucciarelli M. Association of ActA to peptidoglycan revealed by cell wall proteomics of intracellular Listeria monocytogenes. J Biol Chem. 2011;286:34675-89 pubmed publisher
    ..Some of these changes include alterations in the relative amount and the mode of association of certain surface proteins. ..
  21. Paspaliari D, Mollerup M, Kallipolitis B, Ingmer H, Larsen M. Chitinase expression in Listeria monocytogenes is positively regulated by the Agr system. PLoS ONE. 2014;9:e95385 pubmed publisher
    ..Our results highlight a previously unrecognized role of the agr system and suggest that autoinducer-based regulation of chitinolytic systems may be more commonplace than previously thought. ..
  22. Leisner J, Larsen M, Jørgensen R, Brøndsted L, Thomsen L, Ingmer H. Chitin hydrolysis by Listeria spp., including L. monocytogenes. Appl Environ Microbiol. 2008;74:3823-30 pubmed publisher
    ..The chiB and chiA genes are phylogenetically related to various well-characterized chitinases. The potential biological implications of chitinolytic activity of Listeria are discussed...
  23. Chen J, Cheng C, Xia Y, Zhao H, Fang C, Shan Y, et al. Lmo0036, an ornithine and putrescine carbamoyltransferase in Listeria monocytogenes, participates in arginine deiminase and agmatine deiminase pathways and mediates acid tolerance. Microbiology. 2011;157:3150-61 pubmed publisher
    ..5), and corresponded to a loss in ammonia production, indicating that Lmo0036 was responsible for acid tolerance at both sublethal and lethal pH levels. Furthermore, Lmo0036 played a possible role in Listeria virulence...
  24. Fraser K, Harvie D, Coote P, O Byrne C. Identification and characterization of an ATP binding cassette L-carnitine transporter in Listeria monocytogenes. Appl Environ Microbiol. 2000;66:4696-704 pubmed
    ..We conclude that the opuC operon in L. monocytogenes encodes an ABC compatible solute transporter which is capable of transporting L-carnitine and which plays an important role in osmoregulation in this pathogen...
  25. Disson O, Grayo S, Huillet E, Nikitas G, Langa Vives F, Dussurget O, et al. Conjugated action of two species-specific invasion proteins for fetoplacental listeriosis. Nature. 2008;455:1114-8 pubmed publisher
  26. Domann E, Leimeister W chter M, Goebel W, Chakraborty T. Molecular cloning, sequencing, and identification of a metalloprotease gene from Listeria monocytogenes that is species specific and physically linked to the listeriolysin gene. Infect Immun. 1991;59:65-72 pubmed
    ..We have designated this gene mpl for metalloprotease of L. monocytogenes. The gene was present only in pathogenic L. monocytogenes strains, in which it was physically linked to the listeriolysin gene...
  27. Engelbrecht F, Chun S, Ochs C, Hess J, Lottspeich F, Goebel W, et al. A new PrfA-regulated gene of Listeria monocytogenes encoding a small, secreted protein which belongs to the family of internalins. Mol Microbiol. 1996;21:823-37 pubmed
    ..An InlC deletion mutant shows reduced virulence when tested in an intravenous mouse model, but intracellular replication of the mutant in Caco-2 and J774 cells appears to be comparable with that of the wild-type strain...
  28. Marino M, Braun L, Cossart P, Ghosh P. Structure of the lnlB leucine-rich repeats, a domain that triggers host cell invasion by the bacterial pathogen L. monocytogenes. Mol Cell. 1999;4:1063-72 pubmed
    ..The structure also identifies surfaces on the curved and elongated molecule that may constitute additional interaction sites in forming a bacterial-mammalian signaling complex...
  29. Winters D, Ivey D, Maloney T, Johnson M. Characterization by molecular cloning and sequencing of the gene encoding an aminopeptidase from Listeria monocytogenes. Antonie Van Leeuwenhoek. 2000;78:141-51 pubmed
    ..The organization of the locus, designated pep, is presented along with the characterization of the gene products of the pep locus. ..
  30. Okada Y, Makino S, Tobe T, Okada N, Yamazaki S. Cloning of rel from Listeria monocytogenes as an osmotolerance involvement gene. Appl Environ Microbiol. 2002;68:1541-7 pubmed
    ..Our results suggest that the appropriate intracellular concentration of (p)ppGpp is essential for full osmotolerance in L. monocytogenes and that its mechanism is different from that for the accumulation of compatible solutes...
  31. Sandrini M, Clausen A, On S, Aarestrup F, Munch Petersen B, Piskur J. Nucleoside analogues are activated by bacterial deoxyribonucleoside kinases in a species-specific manner. J Antimicrob Chemother. 2007;60:510-20 pubmed
    ..Bacterial dNKs efficiently activate nucleoside analogues in a species-specific manner. Therefore, nucleoside analogues have a potential to be employed as antibiotics in the fight against emerging multiresistant bacteria. ..
  32. Markkula A, Lindstr m M, Johansson P, Bj rkroth J, Korkeala H. Roles of four putative DEAD-box RNA helicase genes in growth of Listeria monocytogenes EGD-e under heat, pH, osmotic, ethanol, and oxidative stress conditions. Appl Environ Microbiol. 2012;78:6875-82 pubmed publisher
    ..This study shows that the putative DEAD-box RNA helicase genes lmo0866 and lmo1450 play important roles in tolerance of L. monocytogenes EGD-e to ethanol, heat, alkali, and oxidative stresses...
  33. Quereda J, Pucciarelli M. Deletion of the membrane protein Lmo0412 increases the virulence of Listeria monocytogenes. Microbes Infect. 2014;16:623-32 pubmed publisher
    ..Taken together, these data suggest a selective advantage conferred by the absence of Lmo0412 for the virulence of L. monocytogenes...
  34. Tiwari K, Birlingmair J, Wilkinson B, Jayaswal R. Role of the twin-arginine translocase (tat) system in iron uptake in Listeria monocytogenes. Microbiology. 2015;161:264-71 pubmed publisher
    ..Hence, we propose that fepB encodes a ferric reductase enzyme, which is translocated by the Tat-translocase system onto the bacterial cell surface, and plays an important role in the reductive iron uptake process in L. monocytogenes. ..
  35. Wang J, Zhou X, Liu S, Li G, Zhang B, Deng X, et al. Novel inhibitor discovery and the conformational analysis of inhibitors of listeriolysin O via protein-ligand modeling. Sci Rep. 2015;5:8864 pubmed publisher
    ..The current MD simulation work provides insights into the mechanism by which the compounds inhibit LLO at the atomic level and will be useful for the development of new, selective LLO inhibitors. ..
  36. Scharf C, Riethdorf S, Ernst H, Engelmann S, V lker U, Hecker M. Thioredoxin is an essential protein induced by multiple stresses in Bacillus subtilis. J Bacteriol. 1998;180:1869-77 pubmed
    ..These increased levels of thioredoxin might help stressed B. subtilis cells to maintain the native and reduced state of cellular proteins...
  37. Christensen D, Benson A, Hutkins R. Cloning and expression of the Listeria monocytogenes scott A ptsH and ptsI genes, coding for HPr and enzyme I, respectively, of the phosphotransferase system. Appl Environ Microbiol. 1998;64:3147-52 pubmed
  38. Rauch M, Luo Q, M ller Altrock S, Goebel W. SigB-dependent in vitro transcription of prfA and some newly identified genes of Listeria monocytogenes whose expression is affected by PrfA in vivo. J Bacteriol. 2005;187:800-4 pubmed publisher
    ..Transcription starting at the prfA promoter PprfA2 was also optimal with SigB-loaded RNA polymerase, suggesting a direct link between SigB- and PrfA-dependent gene expression...
  39. Zhu K, Bayles D, Xiong A, Jayaswal R, Wilkinson B. Precursor and temperature modulation of fatty acid composition and growth of Listeria monocytogenes cold-sensitive mutants with transposon-interrupted branched-chain alpha-keto acid dehydrogenase. Microbiology. 2005;151:615-23 pubmed publisher
    ..monocytogenes to low temperature. This implies that Bkd is not the major cold-regulation point of BCFA synthesis...
  40. Challan Belval S, Gal L, Margiewes S, Garmyn D, Piveteau P, Guzzo J. Assessment of the roles of LuxS, S-ribosyl homocysteine, and autoinducer 2 in cell attachment during biofilm formation by Listeria monocytogenes EGD-e. Appl Environ Microbiol. 2006;72:2644-50 pubmed publisher
  41. Niemann H, J ger V, Butler P, van den Heuvel J, Schmidt S, Ferraris D, et al. Structure of the human receptor tyrosine kinase met in complex with the Listeria invasion protein InlB. Cell. 2007;130:235-46 pubmed publisher
    ..Thus, although it elicits a similar cellular response, InlB is not a structural mimic of HGF/SF...
  42. Iurov D, Egorova I, Varfolomeev A, Kolbasov D, Ermolaeva S. [Influence of mutation L,D-carboxypeptidase-coding gene on dynamics of Listeria infection]. Zh Mikrobiol Epidemiol Immunobiol. 2009;:55-9 pubmed
    ..Disruption of function of Imo0028 gene coding L,D-carboxypeptidase protein, which takes part in metabolism of peptidoglycan, changes dynamics of listeriosis. ..
  43. van der Veen S, Abee T. HrcA and DnaK are important for static and continuous-flow biofilm formation and disinfectant resistance in Listeria monocytogenes. Microbiology. 2010;156:3782-90 pubmed publisher
    ..In conclusion, our study revealed that HrcA and DnaK are important for L. monocytogenes biofilm formation and disinfectant resistance...
  44. Dowd G, Casey P, Begley M, Hill C, Gahan C. Investigation of the role of ZurR in the physiology and pathogenesis of Listeria monocytogenes. FEMS Microbiol Lett. 2012;327:118-25 pubmed publisher
    ..monocytogenes. Quantitative RT-PCR demonstrated significant de-repression of zurA, lmo0153, and lmo1671 in the zurR mutant background indicating that these putative transporters are ZurR regulated...
  45. Hein K, Nissen P, Morth J. Purification, crystallization and preliminary crystallographic studies of a PacL homologue from Listeria monocytogenes. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012;68:424-7 pubmed publisher
  46. Frederiksen R, Leisner J. Effects of Listeria monocytogenes EGD-e and Salmonella enterica ser. Typhimurium LT2 chitinases on intracellular survival in Dictyostelium discoideum and mammalian cell lines. FEMS Microbiol Lett. 2015;362: pubmed publisher
    ..discoideum was clearly reduced for Listeria mutants deficient of ChiB (8-fold) or deficient of both ChiA and ChiB (22-fold). Our findings suggest that chitinases from the two species play different roles in virulence. ..
  47. Sanchez Campillo M, Dramsi S, G mez G mez J, Michel E, Dehoux P, Cossart P, et al. Modulation of DNA topology by flaR, a new gene from Listeria monocytogenes. Mol Microbiol. 1995;18:801-11 pubmed
    ..flaR is the first gene of this class to be described in Gram-positive pathogenic bacteria...
  48. Lenz L, Mohammadi S, Geissler A, Portnoy D. SecA2-dependent secretion of autolytic enzymes promotes Listeria monocytogenes pathogenesis. Proc Natl Acad Sci U S A. 2003;100:12432-7 pubmed publisher
    ..Thus, SecA2-dependent secretion may promote release of muramyl peptides that subvert host pattern recognition...
  49. Popowska M, Markiewicz Z. Murein-hydrolyzing activity of flagellin FlaA of Listeria monocytogenes. Pol J Microbiol. 2004;53:237-41 pubmed
    ..Peptidoglycan hydrolysing activity of FlaA purified by FPLC on Mono-S Sepharose against labelled Escherichia coli murein was demonstrated. ..
  50. Roche S, Gracieux P, Milohanic E, Albert I, Virlogeux Payant I, T moin S, et al. Investigation of specific substitutions in virulence genes characterizing phenotypic groups of low-virulence field strains of Listeria monocytogenes. Appl Environ Microbiol. 2005;71:6039-48 pubmed publisher
    ..These results demonstrate a relationship between the phenotypic classification and the genotypic modifications for at least group I and III strains and suggest a common evolution of these strains within a group...
  51. Sch r J, Stoll R, Schauer K, Loeffler D, Eylert E, Joseph B, et al. Pyruvate carboxylase plays a crucial role in carbon metabolism of extra- and intracellularly replicating Listeria monocytogenes. J Bacteriol. 2010;192:1774-84 pubmed publisher
    ..monocytogenes. The pycA mutant is also unable to replicate in mammalian cells and exhibits high virulence attenuation in the mouse sepsis model...
  52. Gavicherla B, Ritchey L, Gianfelice A, Kolokoltsov A, Davey R, Ireton K. Critical role for the host GTPase-activating protein ARAP2 in InlB-mediated entry of Listeria monocytogenes. Infect Immun. 2010;78:4532-41 pubmed publisher
    ..Collectively, our findings indicate that ARAP2 promotes InlB-mediated entry of Listeria, in part, by antagonizing the host GTPase Arf6...
  53. Corbett D, Schuler S, Glenn S, Andrew P, Cavet J, Roberts I. The combined actions of the copper-responsive repressor CsoR and copper-metallochaperone CopZ modulate CopA-mediated copper efflux in the intracellular pathogen Listeria monocytogenes. Mol Microbiol. 2011;81:457-72 pubmed publisher
    ..Furthermore, CopZ is shown to confer copper resistance in mutants lacking copper-inducible csoR-copA-copZ expression, thus providing protection from the deleterious effects of copper within the cytoplasm...
  54. Halbedel S, Hahn B, Daniel R, Flieger A. DivIVA affects secretion of virulence-related autolysins in Listeria monocytogenes. Mol Microbiol. 2012;83:821-39 pubmed publisher
    ..Thus, our experiments show that DivIVA is an important factor for various listerial traits that are essential for the pathogenicity of this organism...
  55. Samba Louaka A, Stavru F, Cossart P. Role for telomerase in Listeria monocytogenes infection. Infect Immun. 2012;80:4257-63 pubmed publisher
    ..Together, our data provide evidence that these bacteria trigger hTERT degradation, an event that is detrimental to bacterial replication. ..
  56. Lopez V, Navas J, Martínez Suárez J. Low potential virulence associated with mutations in the inlA and prfA genes in Listeria monocytogenes isolated from raw retail poultry meat. J Food Prot. 2013;76:129-32 pubmed publisher
    ..Two of the subtypes accounted for 51% of the isolates. About 40% of isolates (three subtypes) were found to potentially present attenuated virulence because of the presence of mutations in the prfA and inlA genes. ..
  57. Yu M, Zuo J, Gu H, Guo M, Yin Y. Domain function dissection and catalytic properties of Listeria monocytogenes p60 protein with bacteriolytic activity. Appl Microbiol Biotechnol. 2015;99:10527-37 pubmed publisher
    ..The assay for the effect of Lm-p60 on the bacteriolytic activity of lysozyme revealed that the combined use of Lm-p60 protein with lysozyme showed a strong synergistic effect on the bacteriolytic activity. ..
  58. Pillich H, Puri M, Chakraborty T. ActA of Listeria monocytogenes and Its Manifold Activities as an Important Listerial Virulence Factor. Curr Top Microbiol Immunol. 2017;399:113-132 pubmed publisher
    ..These novel properties provide a new view of ActA and help explain its role as an essential virulence factor of L. monocytogenes. ..
  59. Haas A, Goebel W. Cloning of a superoxide dismutase gene from Listeria ivanovii by functional complementation in Escherichia coli and characterization of the gene product. Mol Gen Genet. 1992;231:313-22 pubmed
    ..coli and protected sodA sodB mutants against the toxic effects of paraquat. Subunits of the recombinant Listeria SOD and of both E. coli SODs formed enzymatically active hybrids in vivo. ..
  60. Sanderson S, Campbell D, Shastri N. Identification of a CD4+ T cell-stimulating antigen of pathogenic bacteria by expression cloning. J Exp Med. 1995;182:1751-7 pubmed
    ..We show that the antigenic peptide is derived from a previously unknown listeria gene product with characteristics of a membrane-bound protein...
  61. Zink R, Loessner M, Scherer S. Characterization of cryptic prophages (monocins) in Listeria and sequence analysis of a holin/endolysin gene. Microbiology. 1995;141 ( Pt 10):2577-84 pubmed
  62. Dramsi S, Dehoux P, Lebrun M, Goossens P, Cossart P. Identification of four new members of the internalin multigene family of Listeria monocytogenes EGD. Infect Immun. 1997;65:1615-25 pubmed
    ..The identity of such an aspect remains to be determined...
  63. Promadej N, Fiedler F, Cossart P, Dramsi S, Kathariou S. Cell wall teichoic acid glycosylation in Listeria monocytogenes serotype 4b requires gtcA, a novel, serogroup-specific gene. J Bacteriol. 1999;181:418-25 pubmed
    ..In contrast to gtcA, the latter gene appears conserved among all screened serotypes of L. monocytogenes...
  64. Borezee E, Pellegrini E, Berche P. OppA of Listeria monocytogenes, an oligopeptide-binding protein required for bacterial growth at low temperature and involved in intracellular survival. Infect Immun. 2000;68:7069-77 pubmed
    ..These results show the major role of OppA in the uptake of oligopeptides and the pleiotropic effects of this oligopeptide-binding protein on the behavior of this pathogen in the environment and in its host...
  65. Nightingale K, Windham K, Martin K, Yeung M, Wiedmann M. Select Listeria monocytogenes subtypes commonly found in foods carry distinct nonsense mutations in inlA, leading to expression of truncated and secreted internalin A, and are associated with a reduced invasion phenotype for human intestinal epitheli. Appl Environ Microbiol. 2005;71:8764-72 pubmed publisher
    ..monocytogenes subtypes which are common among U.S. food isolates but rare among human listeriosis isolates carry inlA mutations that are associated with, and possibly at least partially responsible for, an attenuated invasion phenotype...
  66. Okada Y, Okada N, Makino S, Asakura H, Yamamoto S, Igimi S. The sigma factor RpoN (sigma54) is involved in osmotolerance in Listeria monocytogenes. FEMS Microbiol Lett. 2006;263:54-60 pubmed publisher
  67. Ducey T, Page B, Usgaard T, Borucki M, Pupedis K, Ward T. A single-nucleotide-polymorphism-based multilocus genotyping assay for subtyping lineage I isolates of Listeria monocytogenes. Appl Environ Microbiol. 2007;73:133-47 pubmed publisher
    ..DNA sequences were deposited in the GenBank database under accession numbers DQ 812146 to DQ 812517, DQ 843664 to DQ 844598, and AY 512391 to AY 512502...
  68. Krawczyk Balska A, Popowska M, Markiewicz Z. Re-evaluation of the significance of penicillin binding protein 3 in the susceptibility of Listeria monocytogenes to ?-lactam antibiotics. BMC Microbiol. 2012;12:57 pubmed publisher
    ..The observed changes in the morphology of stationary phase cells in response to PBP3 overexpression suggests the involvement of this protein in cell division during this phase of growth...
  69. Pinto D, S o Jos C, Santos M, Chambel L. Characterization of two resuscitation promoting factors of Listeria monocytogenes. Microbiology. 2013;159:1390-401 pubmed publisher
    ..Our study thus supports the hypothesis that Lmo0186 and Lmo2522 are functional equivalents of actinobacteria Rpf proteins and represents the first characterization of two Rpf homologues from firmicutes...
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    ..Our data suggest that AdlP may be a bifunctional protein that represses flagellar motility genes and influences stress responses through its DNA glycosylase activity. ..
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    ..Here we show that the SOS response is activated under these conditions and that deletion of its regulon member yneA results in diminished biofilm formation under continuous-flow conditions...
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    ..From this comparative exoproteomic analysis, new insights into the L. monocytogenes physiology are discussed in relation to its saprophytic and pathogenic lifestyle...
  73. Mengaud J, Braun Breton C, Cossart P. Identification of phosphatidylinositol-specific phospholipase C activity in Listeria monocytogenes: a novel type of virulence factor?. Mol Microbiol. 1991;5:367-72 pubmed
    ..monocytogenes and L. ivanovii. PI-PLC activity was lost and virulence decreased when the plcA gene was disrupted in the chromosome. This suggests that the PI-PLC of L. monocytogenes might be involved in virulence...
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    ..monocytogenes (A. R. Datta, B. A. Wentz, D. Shook, and M. W. Trucksess, Appl. Environ. Microbiol. 54:2933-2937, 1988) were shown to be part of the iap gene...
  76. Metzger R, Brown D, Grealish P, Staver M, Versalovic J, Lupski J, et al. Characterization of the macromolecular synthesis (MMS) operon from Listeria monocytogenes. Gene. 1994;151:161-6 pubmed
    ..C-terminal similarity was observed between DnaG from Lm and Bs. Lm RpoD is similar to Bs SigA, shares identical DNA-binding domains with SigA, and is a member of the sigma 43 subgroup of the sigma 70 family...
  77. Gouin E, Mengaud J, Cossart P. The virulence gene cluster of Listeria monocytogenes is also present in Listeria ivanovii, an animal pathogen, and Listeria seeligeri, a nonpathogenic species. Infect Immun. 1994;62:3550-3 pubmed
    ..This virulence gene cluster was detected exclusively in hemolytic Listeria species, Listeria ivanovii, an animal pathogen, and Listeria seeligeri, a nonpathogenic species...
  78. Gertler F, Niebuhr K, Reinhard M, Wehland J, Soriano P. Mena, a relative of VASP and Drosophila Enabled, is implicated in the control of microfilament dynamics. Cell. 1996;87:227-39 pubmed
    ..Expression of neural-enriched isoforms of Mena in fibroblasts induces the formation of abnormal F-actin-rich outgrowths, supporting a role for this protein in microfilament assembly and cell motility...
  79. Sleator R, Gahan C, Abee T, Hill C. Identification and disruption of BetL, a secondary glycine betaine transport system linked to the salt tolerance of Listeria monocytogenes LO28. Appl Environ Microbiol. 1999;65:2078-83 pubmed
    ..monocytogenes. This mutant is also unable to withstand concentrations of salt as high as can the BetL+ parent, signifying the role of the transporter in Listeria osmotolerance...
  80. Chico Calero I, Su rez M, Gonz lez Zorn B, Scortti M, Slaghuis J, Goebel W, et al. Hpt, a bacterial homolog of the microsomal glucose- 6-phosphate translocase, mediates rapid intracellular proliferation in Listeria. Proc Natl Acad Sci U S A. 2002;99:431-6 pubmed publisher
    ..It is also a clear example of how adaptation to intracellular parasitism by microbial pathogens involves mimicry of physiological mechanisms of their eukaryotic host cells...
  81. Lampidis R, Kostrewa D, Hof H. Molecular characterization of the genes encoding DNA gyrase and topoisomerase IV of Listeria monocytogenes. J Antimicrob Chemother. 2002;49:917-24 pubmed
    ..monocytogenes. However, these heterodiploid strains were not affected in their resistance to nalidixic acid. The effects of the mutant plasmids on ciprofloxacin and sparfloxacin susceptibility were only modest...
  82. Sabet C, Lecuit M, Cabanes D, Cossart P, Bierne H. LPXTG protein InlJ, a newly identified internalin involved in Listeria monocytogenes virulence. Infect Immun. 2005;73:6912-22 pubmed publisher
    ..In conclusion, this postgenomic approach identified InlJ as a new virulence factor among the proteins belonging to the internalin family in L. monocytogenes...
  83. Werbrouck H, Grijspeerdt K, Botteldoorn N, Van Pamel E, Rijpens N, Van Damme J, et al. Differential inlA and inlB expression and interaction with human intestinal and liver cells by Listeria monocytogenes strains of different origins. Appl Environ Microbiol. 2006;72:3862-71 pubmed publisher
    ..monocytogenes strains. The lower capacity of clinical strains to invade HepG2 cells and to induce IL-8 is possibly a mechanism of immune evasion used by specific L. monocytogenes strains...
  84. Rooney A, Ward T. Birth-and-death evolution of the internalin multigene family in Listeria. Gene. 2008;427:124-8 pubmed publisher
  85. Radtke A, Anderson K, Davis M, DiMagno M, Swanson J, O Riordan M. Listeria monocytogenes exploits cystic fibrosis transmembrane conductance regulator (CFTR) to escape the phagosome. Proc Natl Acad Sci U S A. 2011;108:1633-8 pubmed publisher
    ..Our studies suggest that Listeria exploits mechanisms of cellular ion homeostasis to escape the phagosome and emphasize host ion-channel function as a key parameter of bacterial virulence. ..
  86. Han X, Yu R, Ji L, Zhen D, Tao S, Li S, et al. InlB-mediated Listeria monocytogenes internalization requires a balanced phospholipase D activity maintained through phospho-cofilin. Mol Microbiol. 2011;81:860-80 pubmed publisher
    ..These data indicate that cofilin-dependent PLD activation induced by InlB may represent a novel regulation mechanism for efficient Listeria internalization into epithelial cells...
  87. Popowska M, Osi ska M, Rzeczkowska M. N-acetylglucosamine-6-phosphate deacetylase (NagA) of Listeria monocytogenes EGD, an essential enzyme for the metabolism and recycling of amino sugars. Arch Microbiol. 2012;194:255-68 pubmed publisher
    ..monocytogenes is required for cell wall peptidoglycan and teichoic acid biosynthesis and is also essential for bacterial cell growth, cell division, and sensitivity to cell wall hydrolases and peptide antibiotics...
  88. Mariscotti J, Quereda J, Garc a del Portillo F, Pucciarelli M. The Listeria monocytogenes LPXTG surface protein Lmo1413 is an invasin with capacity to bind mucin. Int J Med Microbiol. 2014;304:393-404 pubmed publisher
    ..Taken together, these data indicate that Lmo1413, which we rename LmiA, for Listeria-mucin-binding invasin-A, may promote interaction of bacteria with adhesive host protective components and, in this manner, facilitate bacterial entry...
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    ..DNA hybridization studies indicate that the lma operon is species specific and restricted to pathogenic strains of L. monocytogenes...
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    ..monocytogenes organisms against stress conditions associated with low storage temperatures, exposure to organic acid, and elevated NaCl salt concentrations...
  91. Ondrusch N, Kreft J. Blue and red light modulates SigB-dependent gene transcription, swimming motility and invasiveness in Listeria monocytogenes. PLoS ONE. 2011;6:e16151 pubmed publisher
    ..monocytogenes. In natural environments these effects will result in sometimes random but potentially also cyclic fluctuations of gene activity, depending on the light conditions prevailing in the respective habitat...
  92. Zhang Z, Meng Q, Qiao J, Yang L, Cai X, Wang G, et al. RsbV of Listeria monocytogenes contributes to regulation of environmental stress and virulence. Arch Microbiol. 2013;195:113-20 pubmed publisher
    ..monocytogenes. Our data demonstrate that, in addition to regulating tolerance under environmental stress conditions, RsbV also contributes to regulation of L. monocytogenes virulence...