Lactococcus lactis subsp. lactis


Alias: Lactococcus lactis lactis, "Lactococcus lactis subsp. diacitilactis (sic)" (Garvie and Farrow 1982) Schleifer et al. 1986, "Streptococcus diacetilactis" Matuszewski et al. 1936, Lactobacillus xylosus, Lactobacillus xylosus Kitahara 1938 (Approved Lists 1980), Lactococcus lactis (SUBSP. LACTIS), Lactococcus lactis subsp. lactis (Lister 1873) Schleifer et al. 1986, Streptococcus diacetilactis, Streptococcus lactis subsp. diacetilactis, Streptococcus lactis subsp. diacetilactis (ex Matuszewski et al. 1936) Garvie and Farrow 1982, Streptococcus lactis subsp. lactis, Streptococcus lactis subsp. lactis (Lister 1873) Lohnis 1909

Top Publications

  1. Kojic M, Strahinic I, Fira D, Jovcic B, Topisirovic L. Plasmid content and bacteriocin production by five strains of Lactococcus lactis isolated from semi-hard homemade cheese. Can J Microbiol. 2006;52:1110-20 pubmed
    ..In addition, plasmid curing experiments showed that genes for catabolism or transport of 10 carbohydrates in the strain BGMN1-5 were plasmid located. ..
  2. Stefaniak T, Madej J, Graczyk S, Siwek M, Łukaszewicz E, Kowalczyk A, et al. Selected prebiotics and synbiotics administered in ovo can modify innate immunity in chicken broilers. BMC Vet Res. 2019;15:105 pubmed publisher
    ..Early in ovo treatment of chicken embryos with prebiotics and synbiotics may temporarily modulate not only the production/maturation of leukocytes but also their reactivity. ..
  3. Taniguchi M, Kuda T, Shibayama J, Sasaki T, Michihata T, Takahashi H, et al. In vitro antioxidant, anti-glycation and immunomodulation activities of fermented blue-green algae Aphanizomenon flos-aquae. Mol Biol Rep. 2019;46:1775-1786 pubmed publisher
    ..The increased immunomodulation capacity was also fractionated to mainly 30-100 kDa. These results suggest that the fermented AFA is a more useful material for health foods and supplements. ..
  4. Chen F, Zhang Z, Chen J. Infective endocarditis caused by Lactococcus lactis subsp. lactis and Pediococcus pentosaceus: A case report and literature review. Medicine (Baltimore). 2018;97:e13658 pubmed publisher
    ..Standard interpretation criteria of Clinical and Laboratory Standards Institute (CLSI) for L. lactis should be established, and molecular tests will increase the identification rate of L. lactis infections. ..
  5. Hagiwara A, Imai N, Nakashima H, Toda Y, Kawabe M, Furukawa F, et al. A 90-day oral toxicity study of nisin A, an anti-microbial peptide derived from Lactococcus lactis subsp. lactis, in F344 rats. Food Chem Toxicol. 2010;48:2421-8 pubmed publisher
    ..2%, 1.0% and 5.0% nisin A for 90 days. Therefore, the no-observed-adverse-effect level (NOAEL) for nisin A was concluded to be a dietary level of 5.0% (2996 mg/kg/day for males and 3187 mg/kg/day for females). ..
  6. Carafa I, Stocco G, Franceschi P, Summer A, Tuohy K, Bittante G, et al. Evaluation of autochthonous lactic acid bacteria as starter and non-starter cultures for the production of Traditional Mountain cheese. Food Res Int. 2019;115:209-218 pubmed publisher
    ..rhamnosus BT68 at high concentration is related to the increase of short chain fatty acids and conjugated linoleic acid in cheese after 7 months ripening. ..
  7. Garde S, Avila M, Arias R, Gaya P, Nunez M. Outgrowth inhibition of Clostridium beijerinckii spores by a bacteriocin-producing lactic culture in ovine milk cheese. Int J Food Microbiol. 2011;150:59-65 pubmed publisher
    ..Inclusion of L. lactis subsp. lactis INIA 415 in starter cultures seems a feasible method to prevent late blowing defect in cheese without altering its sensory characteristics. ..
  8. Juturu V, Wu J. Microbial production of bacteriocins: Latest research development and applications. Biotechnol Adv. 2018;36:2187-2200 pubmed publisher
    ..The future of bacteriocins is largely dependent on getting FDA approval for use of other bacteriocins in addition to nisin to promote the research and applications. ..
  9. Xia Y, Cao J, Wang M, Lu M, Chen G, Gao F, et al. Effects of Lactococcus lactis subsp. lactis JCM5805 on colonization dynamics of gut microbiota and regulation of immunity in early ontogenetic stages of tilapia. Fish Shellfish Immunol. 2019;86:53-63 pubmed publisher
    ..However, whether the upregulation of related genes is related to the presence of JCM5805 strain in the intestine requires further verification. ..

More Information

Publications113 found, 100 shown here

  1. Cosentino S, Fadda M, Deplano M, Melis R, Pomata R, Pisano M. Antilisterial activity of nisin-like bacteriocin-producing Lactococcus lactis subsp. lactis isolated from traditional Sardinian dairy products. J Biomed Biotechnol. 2012;2012:376428 pubmed publisher
    ..Our results suggest that these bac+ strains could be potentially applied in cheese manufacturing to control the growth of L. monocytogenes. ..
  2. Kitagawa N, Otani T, Inai T. Nisin, a food preservative produced by Lactococcus lactis, affects the localization pattern of intermediate filament protein in HaCaT cells. Anat Sci Int. 2019;94:163-171 pubmed publisher
    ..Our findings also indicate that CK5 and CK17 can serve as markers for evaluating the effects of nisin on keratinocytes. ..
  3. Zhu D, Liu F, Xu H, Bai Y, Zhang X, Saris P, et al. Isolation of strong constitutive promoters from Lactococcus lactis subsp. lactis N8. FEMS Microbiol Lett. 2015;362: pubmed publisher
    ..In conclusion, four strong constitutive promoters with a wide range of promoter activities were identified and are suitable for protein production in L. lactis. ..
  4. Tschoeke D, Moreira A, Chimetto Tonon L, de Mesquita M, Gregoracci G, Gomez Gil B, et al. Exploring the Genome of Cheese Starter Lactic Acid Bacterium Lactococcus lactis subsp. lactis CECT 4433. Genome Announc. 2014;2: pubmed publisher
    ..lactis CECT 4433, a cheese fermentation starter strain. The genome provides further insight into the genomic plasticity, biocomplexity (including gene strain specifics), and evolution of these genera. ..
  5. Alonso S, Carmen Castro M, Berdasco M, de la Banda I, Moreno Ventas X, de Rojas A. Isolation and Partial Characterization of Lactic Acid Bacteria from the Gut Microbiota of Marine Fishes for Potential Application as Probiotics in Aquaculture. Probiotics Antimicrob Proteins. 2018;: pubmed publisher
    ..These results showed the potential of LAB obtained from the indigenous microbiota of wild marine fishes for use as probiotics in aquaculture. ..
  6. Madej J, Stefaniak T, Bednarczyk M. Effect of in ovo-delivered prebiotics and synbiotics on lymphoid-organs' morphology in chickens. Poult Sci. 2015;94:1209-19 pubmed publisher
    ..This effect is more pronounced after synbiotic treatment than in prebiotic-treated groups. ..
  7. van Mastrigt O, Di Stefano E, Hartono S, Abee T, Smid E. Large plasmidome of dairy Lactococcus lactis subsp. lactis biovar diacetylactis FM03P encodes technological functions and appears highly unstable. BMC Genomics. 2018;19:620 pubmed publisher
    ..Some of the plasmids were easily lost demonstrating that propagation outside the dairy environment should be minimised when studying dairy isolates of L. lactis. ..
  8. Tabanelli G, Montanari C, Bargossi E, Lanciotti R, Gatto V, Felis G, et al. Control of tyramine and histamine accumulation by lactic acid bacteria using bacteriocin forming lactococci. Int J Food Microbiol. 2014;190:14-23 pubmed publisher
    ..This knowledge is essentially aimed to use bacteriocinogenic lactococci as a predictable strategy against aminobiogenic bacteria present in cheese or other fermented foods. ..
  9. Shikano A, Kuda T, Takahashi H, Kimura B. Effects of fermented green-loofah and green-papaya on nitric oxide secretion from murine macrophage raw 264.7 cells. Mol Biol Rep. 2018;45:1013-1021 pubmed publisher
    ..These results suggest that fermented green-loofah and green-papaya suspensions can play both immunostimulatory and anti-inflammatory roles at low and high doses, respectively. ..
  10. Jounai K, Ikado K, Sugimura T, Ano Y, Braun J, Fujiwara D. Spherical lactic acid bacteria activate plasmacytoid dendritic cells immunomodulatory function via TLR9-dependent crosstalk with myeloid dendritic cells. PLoS ONE. 2012;7:e32588 pubmed publisher
    ..Taken together, certain non-pathogenic spherical LAB in wide dietary use has potent and diverse immunomodulatory effects on pDC potentially relevant to anti-viral immunity and chronic inflammatory disease. ..
  11. Haghshenas B, Abdullah N, Nami Y, Radiah D, Rosli R, Khosroushahi A. Different effects of two newly-isolated probiotic Lactobacillus plantarum 15HN and Lactococcus lactis subsp. Lactis 44Lac strains from traditional dairy products on cancer cell lines. Anaerobe. 2014;30:51-9 pubmed publisher
    ..However, precise characterizations and in vitro/in vivo investigations on purified proteins should be conducted before these metabolites are introduced as potential anti-cancer therapeutics. ..
  12. SÅ‚awinska A, Siwek M, Bednarczyk M. Effects of synbiotics injected in ovo on regulation of immune-related gene expression in adult chickens. Am J Vet Res. 2014;75:997-1003 pubmed publisher
    ..Evaluation of immune-related gene expression patterns may be useful when monitoring the effectiveness of synbiotic selection with respect to immunobiotic properties. ..
  13. Oliveira L, Saraiva T, Soares S, Ramos R, Sá P, Carneiro A, et al. Genome Sequence of Lactococcus lactis subsp. lactis NCDO 2118, a GABA-Producing Strain. Genome Announc. 2014;2: pubmed publisher
    ..Here, we report the complete genome sequence of L. lactis NCDO 2118, a strain with probiotic potential activity. ..
  14. Velly H, Renault P, Abraham A, Loux V, Delacroix Buchet A, Fonseca F, et al. Genome Sequence of the Lactic Acid Bacterium Lactococcus lactis subsp. lactis TOMSC161, Isolated from a Nonscalded Curd Pressed Cheese. Genome Announc. 2014;2: pubmed publisher
    ..Here, we report the genome sequence of L. lactis subsp. lactis TOMSC161, isolated from nonscalded curd pressed cheese. This genome sequence provides information in relation to dairy environment adaptation. ..
  15. Nakano K, Minami M, Shinzato M, Shimoji M, Ashimine N, Shiroma A, et al. Complete Genome Sequence of Lactococcus lactis subsp. lactis G50 with Immunostimulating Activity, Isolated from Napier Grass. Genome Announc. 2018;6: pubmed publisher
    ..We determined the complete genome sequence of this strain using the PacBio RS II platform. The single circular chromosome consists of 2,346,663 bp, with 35.03% G+C content and no plasmids. ..
  16. Tsuji R, Komano Y, Ohshio K, Ishii N, Kanauchi O. Long-term administration of pDC stimulative lactic acid bacteria, Lactococcus lactis strain Plasma, prevents immune-senescence and decelerates individual senescence. Exp Gerontol. 2018;111:10-16 pubmed publisher
    ..Therefore, LC-Plasma is suggested to be a useful functional food material for decelerating individual senescence. ..
  17. Ellis M, Shaw K, Jackson S, Daniel S, Knight J. Analysis of commercial kidney stone probiotic supplements. Urology. 2015;85:517-21 pubmed publisher
    ..formigenes or viable oxalate-degrading organisms, and they are unlikely to be of benefit to calcium oxalate kidney stone patients. ..
  18. Ladero V, del Rio B, Linares D, Fernandez M, Mayo B, Martín M, et al. Draft Genome Sequence of the Putrescine-Producing Strain Lactococcus lactis subsp. lactis 1AA59. Genome Announc. 2015;3: pubmed publisher
    ..lactis 1AA59. This strain-isolated from a traditional cheese-produces putrescine, one of the most frequently biogenic amines found in dairy products. ..
  19. Toy N, Özogul F, Özogul Y. The influence of the cell free solution of lactic acid bacteria on tyramine production by food borne-pathogens in tyrosine decarboxylase broth. Food Chem. 2015;173:45-53 pubmed publisher
    ..Consequently, in order to avoid the formation of high concentrations of biogenic amines in fermented food by bacteria, it is advisable to use CFS for food and food products. ..
  20. Nakamura S, Morimoto Y, Kudo S. A lactose fermentation product produced by Lactococcus lactis subsp. lactis, acetate, inhibits the motility of flagellated pathogenic bacteria. Microbiology. 2015;161:701-7 pubmed publisher
    ..lactis. These results highlight the potential use of Lac. lactis for preventing infections by multiple bacterial species. ..
  21. Renye J, Somkuti G. Nisin-induced expression of a recombinant antihypertensive peptide in dairy lactic acid bacteria. Biotechnol Lett. 2015;37:1447-54 pubmed publisher
    ..casei C2 in a chemically defined medium. The use of a nisin as a "food-grade" inducer molecule, and generally-regarded-as-safe LAB species suggests that this system could be used for the production of functional food ingredients. ..
  22. de Souza G, de Carvalho R, de Sousa J, Tavares J, Schaffner D, de Souza E, et al. Effects of the Essential Oil from Origanum vulgare L. on Survival of Pathogenic Bacteria and Starter Lactic Acid Bacteria in Semihard Cheese Broth and Slurry. J Food Prot. 2016;79:246-52 pubmed publisher
  23. Loh J, Kay G, Ting A. Bioencapsulation and Colonization Characteristics of Lactococcus lactis subsp. lactis CF4MRS in Artemia franciscana: a Biological Approach for the Control of Edwardsiellosis in Larviculture. Mar Biotechnol (NY). 2018;20:353-362 pubmed publisher
    ..In conclusion, L. lactis subsp. lactis CF4MRS shows a good efficacy of colonization in Artemia and has the potential for biocontrol/probiotic activity against Edwardsiella sp. infection. ..
  24. Sławińska A, Siwek M, Zylińska J, Bardowski J, Brzezińska J, Gulewicz K, et al. Influence of synbiotics delivered in ovo on immune organs development and structure. Folia Biol (Krakow). 2014;62:277-85 pubmed
    ..In ovo delivery of synbiotics is an efficient mode of immune system stimulation in chickens but its efficiency depends on chicken genotype. ..
  25. Pattanayaiying R, H Kittikun A, Cutter C. Incorporation of nisin Z and lauric arginate into pullulan films to inhibit foodborne pathogens associated with fresh and ready-to-eat muscle foods. Int J Food Microbiol. 2015;207:77-82 pubmed publisher
    ..The results obtained from this study indicate the LAE- and LAE-nisin Z-containing pullulan films displayed excellent inhibition against foodborne pathogens on fresh and further processed muscle foods. ..
  26. Madej J, Bednarczyk M. Effect of in ovo-delivered prebiotics and synbiotics on the morphology and specific immune cell composition in the gut-associated lymphoid tissue. Poult Sci. 2016;95:19-29 pubmed publisher
    ..The data obtained in this study indicated that prebiotics and particularly synbiotics administrated in ovo stimulated GALT development after hatch. ..
  27. Tafreshi S, Mirdamadi S, Norouzian D, Khatami S, Sardari S. Optimization of Non-Nutritional Factors for a Cost-Effective Enhancement of Nisin Production Using Orthogonal Array Method. Probiotics Antimicrob Proteins. 2010;2:267-73 pubmed publisher
    ..7), agitation: 100 rpm and temperature: 27 °C. Under the optimized conditions, maximum nisin production and maximum nisin productivity were 599.70 IU/mL and 37.48 IU/mL/h, respectively. ..
  28. Salazar Montoya J, González Cuello R, Flores Girón E, Ramos Ramírez E. Effect of free and microencapsulated Lactococcus lactis on composition and rheological properties of Manchego-type cheeses during ripening. Food Res Int. 2018;105:59-64 pubmed publisher
    ..32×10-2 and 2.38×10-2s and the Jo values were 29 times higher than the Ji values in the studied cheeses, indicating the loss of elasticity of the cheeses as they ripen. ..
  29. Zuljan F, Espariz M, Blancato V, Esteban L, Alarcón S, Magni C. Draft Genome Sequence of Lactococcus lactis subsp. lactis bv. diacetylactis CRL264, a Citrate-Fermenting Strain. Genome Announc. 2016;4: pubmed publisher
    ..Our genome analysis shows similar genetic organization to other available genomes of L. lactis bv. diacetylactis strains. ..
  30. Sugimura T, Jounai K, Ohshio K, Suzuki H, Kirisako T, Sugihara Y, et al. Long-term administration of pDC-Stimulative Lactococcus lactis strain decelerates senescence and prolongs the lifespan of mice. Int Immunopharmacol. 2018;58:166-172 pubmed publisher
    ..In conclusion, long-term administration of Lc-Plasma can decelerate senescence and prolong lifespan via maintenance of the immune system due to activation of pDCs. ..
  31. Pruszynska Oszmalek E, Kolodziejski P, Stadnicka K, Sassek M, Chalupka D, Kuston B, et al. In ovo injection of prebiotics and synbiotics affects the digestive potency of the pancreas in growing chickens. Poult Sci. 2015;94:1909-16 pubmed publisher
    ..Treatment with the prebiotics and synbiotics did not change the feed conversion ratio but Bi²tos (galacto-oligosaccharide) and inulin (fructan) + Lactococcus lactis subsp. lactis significantly increased final BW. ..
  32. Gabed N, Yang M, Bey Baba Hamed M, Drici H, Gross R, Dandekar T, et al. Draft Genome Sequence of the Moderately Heat-Tolerant Lactococcus lactis subsp. lactis bv. diacetylactis Strain GL2 from Algerian Dromedary Milk. Genome Announc. 2015;3: pubmed publisher
    ..Here, we present the draft genome sequence of this potential new dairy starter strain, which combines thermotolerance and the capacity to metabolize lactose, casein, and citrate. ..
  33. Bezerra T, de Araujo A, do Nascimento E, de Matos Paz J, Gadelha C, Gadelha T, et al. Proteolysis in goat "coalho" cheese supplemented with probiotic lactic acid bacteria. Food Chem. 2016;196:359-66 pubmed publisher
    ..However, over all 28 days, the cheese supplemented with Bifidobacterium lactis in its isolated form showed the highest proteolytic activity, particularly in the hydrolysis of the alpha-s2 and kappa-casein fractions. ..
  34. Jounai K, Sugimura T, Morita Y, Ohshio K, Fujiwara D. Administration of Lactococcus lactis strain Plasma induces maturation of plasmacytoid dendritic cells and protection from rotavirus infection in suckling mice. Int Immunopharmacol. 2018;56:205-211 pubmed publisher
    ..The specific LAB strain may affect the anti-viral immunological profile of IECs via maturation of LP pDCs, leading to protection from RV virus infection in vivo. ..
  35. Chen X, Xu J, Yang L, Yuan Z, Xiao S, Zhang Y, et al. Production of C4 and C5 branched-chain alcohols by engineered Escherichia. coli. J Ind Microbiol Biotechnol. 2015;42:1473-9 pubmed publisher
    ..24 μmol min(-1) mg(-1), respectively. Due to its ability on decarboxylation of α-ketoisovalerate and α-ketoisocaproate, the recombinant E. coli strain showed potential application on isoamyl alcohol and isobutanol production. ..
  36. Kawahara M, Nemoto M, Nakata T, Kondo S, Takahashi H, Kimura B, et al. Anti-inflammatory properties of fermented soy milk with Lactococcus lactis subsp. lactis S-SU2 in murine macrophage RAW264.7 cells and DSS-induced IBD model mice. Int Immunopharmacol. 2015;26:295-303 pubmed publisher
    ..lactis S-SU2. ..
  37. Bolla P, Abraham A, Pérez P, de Los Angeles Serradell M. Kefir-isolated bacteria and yeasts inhibit Shigella flexneri invasion and modulate pro-inflammatory response on intestinal epithelial cells. Benef Microbes. 2016;7:103-110 pubmed publisher
    ..flexneri internalisation into human intestinal epithelial cells, along with the inhibition of the signalling via NF-κB that in turn led to the attenuation of the inflammatory response. ..
  38. Muhammed M, Olsen M, Kot W, Neve H, Castro Mejía J, Janzen T, et al. Investigation of the bacteriophage community in induced lysates of undefined mesophilic mixed-strain DL-cultures using classical and metagenomic approaches. Int J Food Microbiol. 2018;272:61-72 pubmed publisher
    ..Taken together, the majority of the P335 quasi-species phages could represent the induced viral community of the starters and the remaining phage groups mainly represent the background ambient viral community. ..
  39. Lee M, Lee J, Nam Y, Lee J, Seo M, Yi S. Characterization of antimicrobial lipopeptides produced by Bacillus sp. LM7 isolated from chungkookjang, a Korean traditional fermented soybean food. Int J Food Microbiol. 2016;221:12-8 pubmed publisher
  40. Bekhit M, Arab Tehrany E, Kahn C, Cleymand F, Fleutot S, Desobry S, et al. Bioactive Films Containing Alginate-Pectin Composite Microbeads with Lactococcus lactis subsp. lactis: Physicochemical Characterization and Antilisterial Activity. Int J Mol Sci. 2018;19: pubmed publisher
    ..HPMC and starch films containing encapsulated bioactive culture showed a complete inhibition of listerial growth during the first five days of storage at 5 °C and a reduction of 5 logs after 12 days. ..
  41. Fujii T, Tomita Y, Ikushima S, Horie A, Fujiwara D. Draft Genome Sequence of Lactococcus lactis subsp. lactis JCM 5805T, a Strain That Induces Plasmacytoid Dendritic Cell Activation. Genome Announc. 2015;3: pubmed publisher
    ..Here, we report the 2.55-Mb draft genome and annotation of Lactococcus lactis JCM 5805(T). This genome information will provide further insights into the mechanisms underlying the immunomodulatory function of this strain. ..
  42. Perin L, Dal Bello B, Belviso S, Zeppa G, Carvalho A, Cocolin L, et al. Microbiota of Minas cheese as influenced by the nisin producer Lactococcus lactis subsp. lactis GLc05. Int J Food Microbiol. 2015;214:159-167 pubmed publisher
    ..L. lactis subsp. lactis GLc05 influenced also the production of BA determining that their amounts in the cheeses were maintained at acceptable levels for human consumption. ..
  43. de Carvalho R, de Souza G, Honório V, de Sousa J, da Conceição M, Maganani M, et al. Comparative inhibitory effects of Thymus vulgaris L. essential oil against Staphylococcus aureus, Listeria monocytogenes and mesophilic starter co-culture in cheese-mimicking models. Food Microbiol. 2015;52:59-65 pubmed publisher
  44. do Vale Pereira G, da Cunha D, Pedreira Mourino J, Rodiles A, Jaramillo Torres A, Merrifield D. Characterization of microbiota in Arapaima gigas intestine and isolation of potential probiotic bacteria. J Appl Microbiol. 2017;123:1298-1311 pubmed publisher
    ..gigas intestine during different life stages and the presence of LAB strains. It also demonstrated LAB antibiotic resistance and antagonistic behaviour against pathogens isolated from the same fish. ..
  45. Hwanhlem N, Biscola V, El Ghaish S, Jaffrès E, Dousset X, Haertlé T, et al. Bacteriocin-Producing Lactic Acid Bacteria Isolated from Mangrove Forests in Southern Thailand as Potential Bio-Control Agents: Purification and Characterization of Bacteriocin Produced by Lactococcus lactis subsp. lactis KT2W2L. Probiotics Antimicrob Proteins. 2013;5:264-78 pubmed publisher
    ..lactis KT2W2L does not harbor virulence genes cylA, cylB, efaAfs and esp. The bacteriocin and its producing strain may find application as bio-preservatives for reduction in food-spoilage and food-borne pathogens in food products. ..
  46. Xia Y, Lu M, Chen G, Cao J, Gao F, Wang M, et al. Effects of dietary Lactobacillus rhamnosus JCM1136 and Lactococcus lactis subsp. lactis JCM5805 on the growth, intestinal microbiota, morphology, immune response and disease resistance of juvenile Nile tilapia, Oreochromis niloticus. Fish Shellfish Immunol. 2018;76:368-379 pubmed publisher
    ..JCM5805 was more effective than JCM1136 or the mixture of the two for promoting the growth, enhancing the immune status and disease resistance of tilapia. ..
  47. Smigielski A. Characterization of a plasmid involved with cointegrate formation and lactose metabolism in Lactococcus lactis subsp. lactis OZS1. Arch Microbiol. 1990;154:560-5 pubmed
    ..lactis subsp. lactis strains and two L. lactis subsp. cremoris strains showed moderate to strong hybridization to one plasmid in each organism. ..
  48. Pellegrino M, Frola I, Natanael B, Gobelli D, Nader Macías M, Bogni C. In Vitro Characterization of Lactic Acid Bacteria Isolated from Bovine Milk as Potential Probiotic Strains to Prevent Bovine Mastitis. Probiotics Antimicrob Proteins. 2019;11:74-84 pubmed publisher
    ..The strains selected in the present study showed indispensable characteristics for their inclusion in a probiotic formulation to be used at dry-off period for the prevention of bovine mastitis. ..
  49. Uzelac G, Miljkovic M, Lozo J, Radulovic Z, Tosic N, Kojic M. Expression of bacteriocin LsbB is dependent on a transcription terminator. Microbiol Res. 2015;179:45-53 pubmed publisher
  50. Guellerin M, Passerini D, Fontagné Faucher C, Robert H, Gabriel V, Loux V, et al. Complete Genome Sequence of Lactococcus lactis subsp. lactis A12, a Strain Isolated from Wheat Sourdough. Genome Announc. 2016;4: pubmed publisher
    ..The circular chromosome and the four plasmids reveal genes involved in carbohydrate metabolism that are potentially required for the persistence of this strain in such a complex ecosystem. ..
  51. Barbosa I, Oliveira M, Madruga M, Gullón B, Pacheco M, Gomes A, et al. Influence of the addition of Lactobacillus acidophilus La-05, Bifidobacterium animalis subsp. lactis Bb-12 and inulin on the technological, physicochemical, microbiological and sensory features of creamy goat cheese. Food Funct. 2016;7:4356-4371 pubmed
    ..Inulin and probiotics can be used together for the production of creamy goat cheese without negatively affecting the general quality characteristics of the product, and to add value because of its synbiotic potential. ..
  52. Ariana M, Hamedi J. Enhanced production of nisin by co-culture of Lactococcus lactis sub sp. lactis and Yarrowia lipolytica in molasses based medium. J Biotechnol. 2017;256:21-26 pubmed publisher
    ..lactis growth were 50% and 49% higher than that of pure culture, respectively. Also the results showed that specific growth rate of L. lactis increased 4 times more than that of the pure culture. ..
  53. Sheng Y, Yang X, Lian Y, Zhang B, He X, Xu W, et al. Characterization of a cadmium resistance Lactococcus lactis subsp. lactis strain by antioxidant assays and proteome profiles methods. Environ Toxicol Pharmacol. 2016;46:286-291 pubmed publisher
    ..lactis may resist cadmium stress through antioxidant approach and enhanced energy metabolism. The food grade lactis strain may be applied in metal decontamination in environment and food/feed. ..
  54. Sheng Y, Wang Y, Yang X, Zhang B, He X, Xu W, et al. Cadmium tolerant characteristic of a newly isolated Lactococcus lactis subsp. lactis. Environ Toxicol Pharmacol. 2016;48:183-190 pubmed publisher
    ..lactis has great potential to be applied to decontamination of heavy metals. ..
  55. Cirković I, Bozic D, Draganic V, Lozo J, Berić T, Kojic M, et al. Licheniocin 50.2 and Bacteriocins from Lactococcus lactis subsp. lactis biovar. diacetylactis BGBU1-4 Inhibit Biofilms of Coagulase Negative Staphylococci and Listeria monocytogenes Clinical Isolates. PLoS ONE. 2016;11:e0167995 pubmed publisher
    ..monocytogenes. ..
  56. Cornelissen A, Sadovskaya I, Vinogradov E, Blangy S, Spinelli S, Casey E, et al. The Baseplate of Lactobacillus delbrueckii Bacteriophage Ld17 Harbors a Glycerophosphodiesterase. J Biol Chem. 2016;291:16816-27 pubmed publisher
    ..In contrast to GDPDLd17, we could not identify any enzymatic activity for the GDPD-like domain in the neck passage structure of phage 340, a 936-type Lactococcus lactis subsp. lactis bacteriophage. ..
  57. Guarcello R, Carpino S, Gaglio R, Pino A, Rapisarda T, Caggia C, et al. A large factory-scale application of selected autochthonous lactic acid bacteria for PDO Pecorino Siciliano cheese production. Food Microbiol. 2016;59:66-75 pubmed publisher
    ..Thus, the main hypothesis of the work was accepted since the quality parameters of the final cheeses were stabilized, but all cheeses maintained their local typicality. ..
  58. Ren J, Lee H, Yoo S, Yu M, Park H, Na D. Combined chemical and physical transformation method with RbCl and sepiolite for the transformation of various bacterial species. J Microbiol Methods. 2017;135:48-51 pubmed publisher
  59. Huang D, Novel M, Huang X, Novel G. Nonidentity between plasmid and chromosomal copies of ISS1-like sequences in Lactococcus lactis subsp. lactis CNRZ270 and their possible role in chromosomal integration of plasmid genes. Gene. 1992;118:39-46 pubmed
    ..ISS1-like sequences were also found on plasmids of numerous Lc. lactis strains, as well as one out of seven Lactobacillus (Lb.) casei and one out of three Lb. plantarum strains examined. ..
  60. Romero D, Klaenhammer T. Characterization of insertion sequence IS946, an Iso-ISS1 element, isolated from the conjugative lactococcal plasmid pTR2030. J Bacteriol. 1990;172:4151-60 pubmed
    ..IS946 has perfect 18-bp terminal inverted repeats, identical to ISS1, and similarly generated 8-bp direct repeats of the target site upon insertion. ..
  61. Pudlik A, Lolkema J. Substrate specificity of the citrate transporter CitP of Lactococcus lactis. J Bacteriol. 2012;194:3627-35 pubmed publisher
    ..Many of the substrates of CitP are intermediates or products of amino acid metabolism, suggesting that CitP may have a broader physiological function than its role in citrate fermentation alone. ..
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    ..This activity was 4 and ~3 times higher than medium containing 100 % MRS broth without added nisin (~4700 AU/ml) and 100 % MRS broth with 0.15 µg/ml of added nisin (~6650 AU/ml), respectively. ..
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    ..2 %). Collectively, these results suggest that dietary supplementation of L. lactis subsp. lactis at 108 CFU g-1 can promote growth performance, digestive enzyme activity, and disease resistance of L. vannamei. ..
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    ..ORF1 (386 amino acids) was homologous to replication protein RepB. The other open reading frames were cryptic. A small counter-transcript RNA (ctRNA) coding region was also observed. ..
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    ..The knowledge of molecular responses involved in adaptation of L. lactis to the shifts of redox state and pH during milk fermentations is important for the dairy industry to ensure better control of cheese production. ..
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    ..AggL is a new protein belonging to the collagen-binding superfamily of proteins and is sufficient for cell aggregation in lactococci. ..
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    ..Different potential functions of lactococcal AggL and MbpL proteins in the process of adhesion to the gastrointestinal tract are proposed. ..
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    ..Further studies must be conducted to evaluate the success of in vitro assays under food environment conditions and to elucidate the antifungal mechanism of these strains. ..
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    ..5 most probably corresponded to lower concentrations of non-dissociated lactic acid which facilitated the cells to reach the highest maximum active cell counts of the three pH set points. ..
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    ..These results provide the first direct evidence for splicing of a prokaryotic group II intron in vivo and suggest that conjugative transfer is a mechanism for group II intron dissemination in bacteria...
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    ..Expression in E. coli facilitates the use of group II introns for the targeting of specific foreign sequences to a desired site in DNA...
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    ..Our results suggest how the maturase functions in RNA splicing and support the hypothesis that the reverse transcriptase coding region was derived from an independent genetic element that was inserted into a preexisting group II intron...
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    ..Upstream of the origin of replication a nicking site (oriT) was found. This oriT sequence proved to be functional by mobilization of plasmids wearing it. One complete and several partial IS elements were identified on pBL1...
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    ..The phenotype was stable after 100 generations and conferred an effective resistance phenotype against phages of the 936 and c2 species...
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    ..Because of their wide host range, mobile group II introns should be useful for genetic engineering and functional genomics in a wide variety of bacteria...