Lactococcus lactis subsp. cremoris

Summary

Alias: Plasmid pNZ4000, "Streptococcus hollandicus" Scholl 1891, Streptococcus lactis subsp. cremoris, Streptococcus lactis B, Streptococcus hollandicus, Streptococcus cremoris Orla-Jensen 1919 (Approved Lists 1980), Streptococcus cremoris, Lactococcus lactis subsp. cremoris (Orla-Jensen 1919) Schleifer et al. 1986, Lactococcus lactis cremoris, Lactococcus lactis (SUBSP. CREMORIS), Lactococcus cremoris, "Streptococcus lactis B" Ayers et al. 1924, Streptococcus lactis subsp. cremoris (Orla-Jensen 1919) Garvie and Farrow 1982, Lactobacillus cremoris

Top Publications

  1. pmc Molecular cloning and nucleotide sequence of the gene encoding the major peptidoglycan hydrolase of Lactococcus lactis, a muramidase needed for cell separation
    G Buist
    Department of Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Haren, The Netherlands
    J Bacteriol 177:1554-63. 1995
  2. ncbi Detection and characterization of a bacteriocin produced by Lactococcus lactis subsp. cremoris R isolated from radish
    Z Yildirim
    Department of Food Science and Arkansas Biotechnology Center, University of Arkansas, Fayetteville 72704, USA
    Lett Appl Microbiol 26:297-304. 1998
  3. pmc Complete sequences of four plasmids of Lactococcus lactis subsp. cremoris SK11 reveal extensive adaptation to the dairy environment
    Roland J Siezen
    Centre for Molecular andBiomolecular Informatics, Radboud University, P O Box 9010, 6500GL Nijmegen, The Netherlands
    Appl Environ Microbiol 71:8371-82. 2005
  4. doi A new approach for the purification and characterisation of PA49.5, the main prebiotic of Lactococcus lactis subsp. cremoris
    Etienne Dako
    Ecole des sciences des aliments, de Nutrition et d Etudes Familiales, Faculté des sciences de la santé et des services communautaires, Université de Moncton N B Canada, E1A 3E9
    Int J Food Microbiol 126:186-94. 2008
  5. pmc Specificity of hydrolysis of bovine kappa-casein by cell envelope-associated proteinases from Lactococcus lactis strains
    J R Reid
    Department of Chemistry and Biochemistry, Massey University, Palmerston North, New Zealand
    Appl Environ Microbiol 60:801-6. 1994
  6. pmc AbiV, a novel antiphage abortive infection mechanism on the chromosome of Lactococcus lactis subsp. cremoris MG1363
    Jakob Haaber
    Center for Systems Microbiology, DTU BioSys, Technical University of Denmark, Lyngby, Denmark
    Appl Environ Microbiol 74:6528-37. 2008
  7. pmc Complete genome sequence of the prototype lactic acid bacterium Lactococcus lactis subsp. cremoris MG1363
    Udo Wegmann
    Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Kerklaan 30, 9751 NN Haren, The Netherlands
    J Bacteriol 189:3256-70. 2007
  8. ncbi An X-prolyl dipeptidyl aminopeptidase from Lactococcus lactis: cloning, expression in Escherichia coli, and application for removal of N-terminal Pro-Pro from recombinant proteins
    Ming Xin
    Biopharmaceutical College, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, People s Republic of China
    Protein Expr Purif 24:530-8. 2002
  9. pmc Lactococcin A, a new bacteriocin from Lactococcus lactis subsp. cremoris: isolation and characterization of the protein and its gene
    H Holo
    Laboratory of Microbial Gene Technology, Oslo, Norway
    J Bacteriol 173:3879-87. 1991
  10. pmc Characterization and role of the branched-chain aminotransferase (BcaT) isolated from Lactococcus lactis subsp. cremoris NCDO 763
    M Yvon
    Unité de Recherche de Biochimie et Structure des Protéines, I N R A, 78352 Jouy en Josas, France
    Appl Environ Microbiol 66:571-7. 2000

Scientific Experts

Detail Information

Publications117 found, 100 shown here

  1. pmc Molecular cloning and nucleotide sequence of the gene encoding the major peptidoglycan hydrolase of Lactococcus lactis, a muramidase needed for cell separation
    G Buist
    Department of Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Haren, The Netherlands
    J Bacteriol 177:1554-63. 1995
    ..By replacement recombination, an acmA deletion mutant which grew as long chains was constructed, indicating that AcmA is required for cell separation...
  2. ncbi Detection and characterization of a bacteriocin produced by Lactococcus lactis subsp. cremoris R isolated from radish
    Z Yildirim
    Department of Food Science and Arkansas Biotechnology Center, University of Arkansas, Fayetteville 72704, USA
    Lett Appl Microbiol 26:297-304. 1998
    ..Lactococcin R differs from nisin in having a lower molecular weight, 2.5 kDa vs 3.4 kDa, and in being sensitive to pepsin and alpha-chymotrypsin to which nisin is resistant...
  3. pmc Complete sequences of four plasmids of Lactococcus lactis subsp. cremoris SK11 reveal extensive adaptation to the dairy environment
    Roland J Siezen
    Centre for Molecular andBiomolecular Informatics, Radboud University, P O Box 9010, 6500GL Nijmegen, The Netherlands
    Appl Environ Microbiol 71:8371-82. 2005
    ..A substantial number of these "adaptation" genes have not been described before on L. lactis plasmids. Moreover, several genes were identified for the first time in L. lactis, possibly reflecting horizontal gene transfer...
  4. doi A new approach for the purification and characterisation of PA49.5, the main prebiotic of Lactococcus lactis subsp. cremoris
    Etienne Dako
    Ecole des sciences des aliments, de Nutrition et d Etudes Familiales, Faculté des sciences de la santé et des services communautaires, Université de Moncton N B Canada, E1A 3E9
    Int J Food Microbiol 126:186-94. 2008
    ..Analysis by denaturing polyacrylamide gel electrophoresis with Mc5 cell walls incorporated as the autolysin's substrate identified a band corresponding to PA49.5 in the second peak of protein secretion...
  5. pmc Specificity of hydrolysis of bovine kappa-casein by cell envelope-associated proteinases from Lactococcus lactis strains
    J R Reid
    Department of Chemistry and Biochemistry, Massey University, Palmerston North, New Zealand
    Appl Environ Microbiol 60:801-6. 1994
    ..abstract truncated at 250 words)..
  6. pmc AbiV, a novel antiphage abortive infection mechanism on the chromosome of Lactococcus lactis subsp. cremoris MG1363
    Jakob Haaber
    Center for Systems Microbiology, DTU BioSys, Technical University of Denmark, Lyngby, Denmark
    Appl Environ Microbiol 74:6528-37. 2008
    ..The mode of action of AbiV is unknown, but the activity of AbiV prevented cleavage of the replicated phage DNA of 936-like phages...
  7. pmc Complete genome sequence of the prototype lactic acid bacterium Lactococcus lactis subsp. cremoris MG1363
    Udo Wegmann
    Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Kerklaan 30, 9751 NN Haren, The Netherlands
    J Bacteriol 189:3256-70. 2007
    ..The availability of the L. lactis MG1363 genome sequence will reinforce its status as the prototype among lactic acid bacteria through facilitation of further applied and fundamental research...
  8. ncbi An X-prolyl dipeptidyl aminopeptidase from Lactococcus lactis: cloning, expression in Escherichia coli, and application for removal of N-terminal Pro-Pro from recombinant proteins
    Ming Xin
    Biopharmaceutical College, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing, People s Republic of China
    Protein Expr Purif 24:530-8. 2002
    ....
  9. pmc Lactococcin A, a new bacteriocin from Lactococcus lactis subsp. cremoris: isolation and characterization of the protein and its gene
    H Holo
    Laboratory of Microbial Gene Technology, Oslo, Norway
    J Bacteriol 173:3879-87. 1991
    ..The other lactococcal strains transformed with the same recombinant plasmid became resistant to LCN-A but did not produce any detectable amount of the bacteriocin...
  10. pmc Characterization and role of the branched-chain aminotransferase (BcaT) isolated from Lactococcus lactis subsp. cremoris NCDO 763
    M Yvon
    Unité de Recherche de Biochimie et Structure des Protéines, I N R A, 78352 Jouy en Josas, France
    Appl Environ Microbiol 66:571-7. 2000
    ..Since this enzyme is still active under cheese-ripening conditions, it certainly plays a major role in cheese flavor development...
  11. pmc Duplication of the pepF gene and shuffling of DNA fragments on the lactose plasmid of Lactococcus lactis
    M Nardi
    Unité de Recherches de Biochimie et Structure des Protéines, INRA, Jouy en Josas, France
    J Bacteriol 179:4164-71. 1997
    ..This suggests that the duplication of pepF occurred by recombination from the chromosome of an L. lactis subsp. lactis strain followed by gene transfer. We discuss the possible functions of PepF and the role of its amplification...
  12. ncbi [Influence of expression of transglutaminase on the growth of Lactococcus lactis]
    Rui Yan Fu
    Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Southern Yangtze University, Wuxi 214036, China
    Wei Sheng Wu Xue Bao 45:510-5. 2005
    ....
  13. doi Genotypic and technological characterization of Lactococcus lactis isolates involved in processing of artisanal Manchego cheese
    P Nieto-Arribas
    Departamento de Química Analítica y Tecnología de Alimentos, Facultad de Quimicas, Universidad de Castilla La Mancha, Ciudad Real, Spain
    J Appl Microbiol 107:1505-17. 2009
    ..Genotypic and technological characterization of wild lactococci isolated from artisanal Manchego cheese during the ripening process for selection of suitable starter cultures...
  14. doi The effect of ripening and storage conditions on the distribution of tyramine, putrescine and cadaverine in Edam-cheese
    Leona Buňková
    Department of Fats, Tensides and Cosmetics Technology, Faculty of Technology, Tomas Bata University in Zlin, nam T G Masaryka 275, 76319 Zlín, Czech Republic
    Food Microbiol 27:880-8. 2010
    ..In starter bacteria Lactococcus lactis subsp. lactis and Lactococcus lactis subsp. cremoris the decarboxylase activity tested was not detected...
  15. pmc Comparative genomics and transduction potential of Enterococcus faecalis temperate bacteriophages
    Azra Yasmin
    School of Biological Sciences, University of Liverpool, Liverpool, United Kingdom
    J Bacteriol 192:1122-30. 2010
    ..The eight phages were tested for their ability to package host DNA, and three were shown to be very effective for generalized transduction of naive host cells of the laboratory strains OG1RF and JH2-2...
  16. ncbi Molecular characterization of the restriction endonuclease gene (scrFIR) associated with the ScrFI restriction/modification system from Lactococcus lactis subsp. cremoris UC503
    D P Twomey
    Department of Microbiology, University College, Cork, Ireland
    Microbiology 143:2277-86. 1997
    ..The ability of ScrFI to cleave non-canonically modified 5' CCNGG 3' sequences suggested that some ScrFI sites may require complex modifications to fully impair digestion by this enzyme...
  17. ncbi Effect of liquid feeding weaned pigs on growth performance to harvest
    P G Lawlor
    Pig Production Department, Teagasc, Moorepark Research Centre, Fermoy Co, Cork, Ireland
    J Anim Sci 80:1725-35. 2002
    ..No benefit arose from feeding fresh liquid feed or fermented liquid feed. Growth performance from d 28 after weaning to harvest was not improved by any liquid feed treatment...
  18. pmc The riboflavin transporter RibU in Lactococcus lactis: molecular characterization of gene expression and the transport mechanism
    Catherine M Burgess
    Alimentary Pharmabiotic Centre, Department of Microbiology and Biosciences Institute, National University of Ireland Cork, Western Road, Cork, Ireland
    J Bacteriol 188:2752-60. 2006
    ..The presented transport data are consistent with a uniport mechanism for riboflavin translocation and provide the first detailed molecular and functional analysis of a bacterial protein involved in riboflavin transport...
  19. pmc Genetic organization and molecular analysis of the EcoVIII restriction-modification system of Escherichia coli E1585-68 and its comparison with isospecific homologs
    Iwona Mruk
    Department of Microbiology, University of Gdansk, Kladki 24, 80 822 Gdansk, Poland
    Appl Environ Microbiol 69:2638-50. 2003
    ..LlaCI but not with M. HindIII. R. EcoVIII requires Mg(II) ions for phosphodiester bond cleavage. We found that the same ions are strong inhibitors of the M. EcoVIII enzyme. The biological implications of this finding are discussed...
  20. pmc Improved enumeration of lactic acid bacteria in mesophilic dairy starter cultures by using multiplex quantitative real-time PCR and flow cytometry-fluorescence in situ hybridization
    Udo Friedrich
    Danisco Deutschland GmbH, Busch Johannsen Str 1, D 25899 Niebüll, Germany
    Appl Environ Microbiol 72:4163-71. 2006
    ..lactis subsp. cremoris. Quantitative real-time PCR and FLOW-FISH were found to be effective and accurate tools for the bacterial community analysis of complex starter cultures...
  21. ncbi Effectiveness and stability of plastic films coated with nisin for inhibition of Listeria monocytogenes
    Hudaa Neetoo
    Department of Animal and Food Sciences, University of Delaware, Newark, Delaware 19716 2150, USA
    J Food Prot 70:1267-71. 2007
    ..The results of this study demonstrate that commercially available packaging films can be coated with nisin and the resulting antimicrobial films can be conveniently stored at room temperature with no adverse effect on nisin activity...
  22. pmc Evidence for horizontal transfer of SsuDAT1I restriction-modification genes to the Streptococcus suis genome
    T Sekizaki
    National Institute of Animal Health, Tsukuba, Ibaraki 305 0856, Japan
    J Bacteriol 183:500-11. 2001
    ..These results suggest that the SsuDAT1I system could have been integrated into the S. suis chromosome by an illegitimate recombination mechanism...
  23. doi Production of fresh Cheddar cheese curds with controlled postacidification and enhanced flavor
    D St-Gelais
    Food Research and Development Centre, Agriculture and Agri Food Canada, 3600 Casavant Blvd West, Saint Hyacinthe, Quebec, Canada J2S 8E3
    J Dairy Sci 92:1856-63. 2009
    ..cheese manufacturing, streptococci became the dominant microflora in all cheeses, whereas populations of Lactococcus cremoris and L. diacetylactis decreased. During cheese storage, viable counts of L...
  24. pmc Characterization, expression, and mutation of the Lactococcus lactis galPMKTE genes, involved in galactose utilization via the Leloir pathway
    Benoît P Grossiord
    NIZO Food Research, 6710 BA Ede Laboratory of Microbiology, Wageningen University, 6703 CT Wageningen, The Netherlands
    J Bacteriol 185:870-8. 2003
    ..Recovery of the wild-type phenotype for the galE mutant was obtained either by genetic complementation or by addition of galactose to the growth medium...
  25. pmc Identification and characterization of lactococcal-prophage-carried superinfection exclusion genes
    Jennifer Mahony
    Department of Microbiology, University College Cork, Western Road, Cork, Ireland
    Appl Environ Microbiol 74:6206-15. 2008
    ..Sie-specifying genes found on the MG1363 prophages are also present in various lactococcal strains, whereas the prophage-encoded Sie systems of IL1403 do not appear to be as widely disseminated...
  26. ncbi Feasibility studies to control acute diarrhoea in children by feeding fermented milk preparations Actimel and Indian Dahi
    K N Agarwal
    Department of Paediatrics, University College of Medical Sciences and GTB Hospital, Delhi, India
    Eur J Clin Nutr 56:S56-9. 2002
    ..Group 2 was given Indian Dahi (Lf 40) containing 10(8) of each Lactococcus lactis, Lactococcus lactis cremoris and Leuconostac mesenteroides cremoris per gram...
  27. pmc Genetic characterization of the major lactococcal aromatic aminotransferase and its involvement in conversion of amino acids to aroma compounds
    L Rijnen
    Unité de Recherches de Biochimie et Structure des Protéines, INRA, 78352 Jouy en Josas Cedex, France
    Appl Environ Microbiol 65:4873-80. 1999
    ..However, another biosynthesis aromatic aminotransferase is induced in the absence of phenylalanine in the culture medium...
  28. pmc An aminotransferase from Lactococcus lactis initiates conversion of amino acids to cheese flavor compounds
    M Yvon
    Unité de Recherche de Biochimie et Structure des Protéines, I N R A, Jouy en Josas, France
    Appl Environ Microbiol 63:414-9. 1997
    ..5 kDa. The activity of the enzyme is optimal between pH 6.5 and 8 and between 35 and 45 degrees C, but it is still active under cheese-ripening conditions...
  29. ncbi Cloning and verification of the Lactococcus lactis pyrG gene and characterization of the gene product, CTP synthase
    S L Wadskov-Hansen
    Department of Microbiology, Technical University of Denmark, Building 301, DK 2800 Lyngby, Denmark
    J Biol Chem 276:38002-9. 2001
    ..As for other CTP synthases, the oligomeric structure of the lactococcal enzyme was found to be a tetramer, but unlike most of the other previously characterized enzymes, the tetramer was very stable even at dilute enzyme concentrations...
  30. pmc Characterization of a thiol-dependent endopeptidase from Lactobacillus helveticus CNRZ32
    K M Fenster
    Department of Food Science, University of Wisconsin Madison 53706, USA
    J Bacteriol 179:2529-33. 1997
    ..1). PepE hydrolyzed internal peptide bonds in Met-enkephalin and bradykinin; however, hydrolysis of alpha-, beta-, and kappa-caseins was not detected...
  31. ncbi Sequencing of variable regions of the 16S rRNA gene for identification of lactic acid bacteria isolated from the intestinal microbiota of healthy salmonids
    José Luis Balcázar
    Laboratory of Fish Pathology, Faculty of Veterinary Sciences, University of Zaragoza, Zaragoza 50013, Spain
    Comp Immunol Microbiol Infect Dis 30:111-8. 2007
    ..cremoris, Lactococcus lactis subsp. lactis, and Leuconostoc mesenteroides. The method described was found to be a very simple, rapid, specific, and low-cost tool for the identification of unknown strains of LAB...
  32. ncbi [Comparison of the homologous SfeI and LlaBI restriction-modification systems]
    S S Okhapkina
    Institute of Molecular Biology, Vektor State Research Center of Virology and Biotechnology, Kol tsovo, Novosibirsk Region, 633159 Russia
    Mol Biol (Mosk) 36:432-7. 2002
    ..No homology was observed between operon-flanking sequences of the two closely related species, suggesting horizontal transfer of the operon...
  33. pmc Cloning, sequencing, and expression of the pyruvate carboxylase gene in Lactococcus lactis subsp. lactis C2
    H Wang
    Department of Food Science and Nutrition, University of Minnesota, St Paul, Minnesota 55108, USA
    Appl Environ Microbiol 66:1223-7. 2000
    ..lactis KB4. The deduced lactococcal Pyc protein was highly homologous to Pyc sequences of other bacteria. The pyc gene was also detected in Lactococcus lactis subsp. cremoris and L. lactis subsp. lactis bv. diacetylactis strains...
  34. ncbi Cloning, sequencing and comparison of three lactococcal L-lactate dehydrogenase genes
    S R Swindell
    AFRC Institute of Food Research, Norwich Laboratory, Colney, UK
    Microbiology 140:1301-5. 1994
    ..9% homologous. Our results provide further evidence that L. lactis subsp. Lactis MG1363 and other L. lactis subsp. Lactis NCDO 712 derived strains should be reclassified as Lactococcus lactis subsp. cremoris...
  35. pmc Cloning and sequencing of LlaDCHI [corrected] restriction/modification genes from Lactococcus lactis and relatedness of this system to the Streptococcus pneumoniae DpnII system
    S Moineau
    Quest International, Sarasota, Florida 34243, USA
    Appl Environ Microbiol 61:2193-202. 1995
    ..The deduced amino acid sequence of M.LlaIIA was 75% identical with that of M.DpnII, whereas M.LlaIIB was 88% identical with M.DpnA. However, R.LlalII shared only 31% identity with R.DpnII...
  36. ncbi [Purulent pleurisy due to lactococcus lactis cremoris]
    A Mofredj
    Rev Mal Respir 23:485-6. 2006
  37. pmc Phage TP901-1 site-specific integrase functions in human cells
    Stephanie M Stoll
    Department of Genetics, Stanford University School of Medicine, Stanford, California 94305 5120, USA
    J Bacteriol 184:3657-63. 2002
    ..The TP901-1 phage integrase thus represents a new reagent for manipulating DNA in living mammalian cells...
  38. ncbi Introducing glutathione biosynthetic capability into Lactococcus lactis subsp. cremoris NZ9000 improves the oxidative-stress resistance of the host
    Rui Yan Fu
    The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Southern Yangtze University, Wuxi 214036, People s Republic of China
    Metab Eng 8:662-71. 2006
    ..We conclude that the resistance of L. lactis subsp. cremoris NZ9000 to oxidative stress can be increased in engineered cells with glutathione producing capability...
  39. pmc Two 2[5H]-furanones as possible signaling molecules in Lactobacillus helveticus
    Maurice Ndagijimana
    Dipartimento Scienze degli Alimenti, Alma Mater Studiorum, University of Bologna, Via Fanin 46, 40127 Bologna, Italy
    Appl Environ Microbiol 72:6053-61. 2006
    ..cremoris or to those identified in some cheeses with Lactobacillus helveticus as a starter culture...
  40. ncbi Proteome analysis of the purine stimulon from Lactococcus lactis
    Natascha H Beyer
    Protein Research Group, Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark
    Proteomics 3:786-97. 2003
    ..A success rate of 68% indicates that it may be feasible to perform proteomics based upon genomic sequences of relatives outside the genus...
  41. ncbi Characterization of the LlaCI methyltransferase from Lactococcus lactis subsp. cremoris W15 provides new insights into the biology of type II restriction-modification systems
    Iwona Mruk
    Department of Microbiology, University of Gdansk, Kładki 24, 80 822 Gdansk, Poland
    Microbiology 149:3331-41. 2003
    ..This observation suggests that sensitivity of the M.LlaCI to Mg(2+) may strengthen the restriction activity of the cognate endonuclease in the bacterial cell. Other biological implications of this finding are also discussed...
  42. ncbi Peritonitis due to Lactococcus cremoris in an automated peritoneal dialysis patient
    Olivier Mat
    Nephrol Dial Transplant 18:2690-1. 2003
  43. ncbi Resin straw as an alternative system to securely store frozen microorganisms
    Bouachanh Thammavongs
    Laboratoire de Microbiologie Alimentaire EA3213 USC INRA, Universite de Caen Basse Normandie, 14032 Caen cedex 05, France
    J Microbiol Methods 57:181-6. 2004
    ....
  44. ncbi Characterization of mesentericin ST99, a bacteriocin produced by Leuconostoc mesenteroides subsp. dextranicum ST99 isolated from boza
    Svetoslav D Todorov
    Department of Microbiology, University of Stellenbosch, 7600, Stellenbosch, South Africa
    J Ind Microbiol Biotechnol 31:323-9. 2004
    ..Precipitation with ammonium sulfate (70% saturation), followed by Sep-Pack C18 chromatography and reverse-phase HPLC on a C18 Nucleosil column yielded one antimicrobial peptide...
  45. ncbi Phenotypic identification and technological properties of lactic acid bacteria isolated from traditionally processed fish products of the Eastern Himalayas
    Namrata Thapa
    Department of Zoology, Sikkim Government College, Gangtok 737102, Sikkim, India
    Int J Food Microbiol 107:33-8. 2006
    ..None of the strains produced biogenic amines in the method applied. This paper is the first report on the microbial composition, mostly lactic acid bacteria, of traditionally processed fish products of Eastern Himalayas...
  46. ncbi Phenotypic and genetic diversity of Lactococcus lactis and Enterococcus spp. strains isolated from Northern Spain starter-free farmhouse cheeses
    Susana Delgado
    Instituto de Productos Lácteos de Asturias CSIC, Carretera de Infiesto s n, 33300, Asturias, Villaviciosa, Spain
    Int J Food Microbiol 90:309-19. 2004
    ..Two simple, rapid and cheap techniques (partial ARDRA and SDS-PAGE) are proposed as reliable tools for the classification and typing of new lactococcal-like isolates...
  47. pmc Complete genome sequence of Lactococcus lactis subsp. cremoris A76
    Alexander Bolotin
    INRA, AgroParisTech, UMR1319 MICALIS, Jouy en Josas, France
    J Bacteriol 194:1241-2. 2012
    ..lactis subsp. lactis rather than to the L. lactis subsp. cremoris lineage. This indicates the existence of genetic exchange between the diverse subspecies, presumably related to the technological process...
  48. pmc Design and Construction of a Single-Tube, LATE-PCR, Multiplex Endpoint Assay with Lights-On/Lights-Off Probes for the Detection of Pathogens Associated with Sepsis
    Rachel K Carver-Brown
    Department of Biology, Brandeis University, Waltham, MA 02453 2728, USA
    J Pathog 2012:424808. 2012
    ..Significance and Impact of the Study. This assay uses new technology to achieve an advance in the field of molecular diagnostics: a single-tube multiplex assay for identification of pathogens commonly associated with sepsis...
  49. pmc Identification of a gene required for maturation of an extracellular lactococcal serine proteinase
    A J Haandrikman
    Department of Genetics, University of Groningen, The Netherlands
    J Bacteriol 171:2789-94. 1989
    ..Furthermore, deletion of the 130 C-terminal amino acids of the Wg2 proteinase prevented attachment of the enzyme to lactococcal cells...
  50. doi Dried tomato-flavored probiotic cream cheese with Lactobacillus paracasei
    Marilsa S S Santini
    Univ Norte do Paraná UNOPAR, Mestrado em Ciência e Tecnologia do Leite, Av Paris, 375, 86041 140, Londrina, PR, Brazil
    J Food Sci 77:M604-8. 2012
    ..Cream cheeses C and P did not differ on the sensory tests, both obtaining good overall acceptance by the consumers, of which 82.6% stated that they certainly or probably would buy the product...
  51. doi Enhancement of succinate production by metabolically engineered Escherichia coli with co-expression of nicotinic acid phosphoribosyltransferase and pyruvate carboxylase
    Jiangfeng Ma
    State Key Laboratory of Materials Oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing University of Technology, Nanjing, 211816, Jiangsu, China
    Appl Microbiol Biotechnol 97:6739-47. 2013
    ..Furthermore, when the reducing agent dithiothreitol or reduced carbon source sorbitol was added, the cell growth and carbon source consumption rate of BA016 was reasonably enhanced and succinate productivity increased...
  52. ncbi Characterization of LlaCI, a new restriction-modification system from Lactococcus lactis subsp. cremoris W15
    A Madsen
    Department of Dairy and Food Science, The Royal Veterinary and Agricultural University, Frederiksberg C, Denmark
    Biol Chem 379:443-9. 1998
    ..It shows 24% identity to the HindIII endonuclease...
  53. doi pDB2011, a 7.6 kb multidrug resistance plasmid from Listeria innocua replicating in Gram-positive and Gram-negative hosts
    David Bertsch
    Laboratory of Food Biotechnology, Institute of Food, Nutrition and Health, ETH Zurich, Schmelzbergstrasse 7, 8092 Zurich, Switzerland
    Plasmid 70:284-7. 2013
    ..This study reports the first multidrug resistance plasmid in L. innocua. A large potential for dissemination of pDB2011 is indicated by its host range of both Gram-positive and Gram-negative bacteria...
  54. doi Cloning, production, and functional expression of the bacteriocin sakacin A (SakA) and two SakA-derived chimeras in lactic acid bacteria (LAB) and the yeasts Pichia pastoris and Kluyveromyces lactis
    Juan J Jimenez
    Departamento de Nutricion, Bromatologia y Tecnologia de los Alimentos, Facultad de Veterinaria, Universidad Complutense de Madrid UCM, Avenida Puerta de Hierro, S N, 28040, Madrid, Spain
    J Ind Microbiol Biotechnol 40:977-93. 2013
    ....
  55. ncbi Resident lactic acid bacteria in raw milk Canestrato Pugliese cheese
    L Aquilanti
    Dipartimento di Scienze degli Alimenti, Universita Politecnica delle Marche, Ancona, Italy
    Lett Appl Microbiol 43:161-7. 2006
    ..Investigation of the autochthonous lactic acid bacteria (LAB) population of the raw milk protected designation of origin Canestrato Pugliese cheese using phenotypic and genotypic methodologies...
  56. pmc Activation and transfer of the chromosomal phage resistance mechanism AbiV in Lactococcus lactis
    Jakob Haaber
    Center for Systems Microbiology, DTU Systems Biology, Technical University of Denmark, DK 2800 Lyngby, Denmark
    Appl Environ Microbiol 75:3358-61. 2009
    ..Transfer of abiV between two lactococcal strains, most likely by conjugation, was also demonstrated. To our knowledge, this is the first report of natural transfer of a chromosomally encoded phage resistance mechanism...
  57. pmc DNA sequencing and homologous expression of a small peptide conferring immunity to gassericin A, a circular bacteriocin produced by Lactobacillus gasseri LA39
    Yasushi Kawai
    Laboratory of Animal Products Chemistry, Biological Resource Science, Graduate School of Agricultural Science, Tohoku University, Aoba ku, Sendai, Japan
    Appl Environ Microbiol 75:1324-30. 2009
    ..Comparison of GaaI to peptides with similar characteristics found in the circular bacteriocin gene loci is discussed...
  58. ncbi Phenotypic and genotypic characterization of lactic acid bacteria isolated from Artisanal Italian goat cheese
    E Colombo
    Dipartimento di Scienze e Tecnologie Alimentari e Microbiologiche sez, Microbiologia Agraria Alimentare Ecologica, Universita degli Studi di Milano, Via Celoria, 2 201333 Milano, Italy
    J Food Prot 73:657-62. 2010
    ..faecium, E. durans, E. gilvus, and E. casseliflavus) were isolated with the greatest frequency from ripened cheese samples. Occasionally, Leuconostoc mesenteroides, Leuconostoc lactis, and Lactobacillus paraplantarum also were isolated...
  59. doi Characterization of certain bacterial strains for potential use as starter or probiotic cultures in dairy products
    A Monteagudo-Mera
    Departamento de Biologia Molecular, Universidad de Leon, 24071 Leon, Spain
    J Food Prot 74:1379-86. 2011
    ..L. mesenteroides was the only strain D(2)-lactic acid producer. The selection of any particular strain for probiotic or dairy cultures should be performed according to the technological and/or functional abilities needed...
  60. pmc Molecular characterization of lactococcal bacteriophage Tuc2009 and identification and analysis of genes encoding lysin, a putative holin, and two structural proteins
    E K Arendt
    National Food Biotechnology Centre, University College, Cork, Ireland
    Appl Environ Microbiol 60:1875-83. 1994
    ..The putative holin, which is thought to be involved in the release of lysin from the cytoplasm, contains two strongly hydrophobic presumptive transmembrane domains and a highly charged C-terminal domain...
  61. doi Lactococcus lactis subsp. cremoris FC alleviates symptoms of colitis induced by dextran sulfate sodium in mice
    Yosuke Nishitani
    Organization of Advanced Science and Technology, Kobe University, 1 1 Rokkodai cho, Nada Ku, Kobe 657 8501, Japan
    Int Immunopharmacol 9:1444-51. 2009
    ..7 cells. Our findings indicate that administration of L. lactis subsp. cremoris FC improves negative effects of DSS-induced colitis in mice through the inhibition of inflammatory cell infiltration...
  62. ncbi Regulation of the ribonucleotide reductases in Lactococcus lactis subsp. cremoris
    I Akyol
    Animal Science Department, Agriculture Faculty, Kahramanmaras Sutcu Imam University, 46060, Kahramanmaras, Turkey
    Acta Biol Hung 58:105-14. 2007
    ..Constructed plasmid was transferred into wild type (MG1363), single mutant (flpA orflpB) and double mutant (flpAB). Aerobically, nrdH promoter activity is 15-fold higher than anaerobic expression...
  63. doi Behavior and viability of spontaneous oxidative stress-resistant Lactococcus lactis mutants in experimental fermented milk processing
    M N Oliveira
    Departamento de Tecnologia Farmacêutica e Bioquímica, Universidade de Sao Paulo, Sao Paulo, SP, Brasil
    Genet Mol Res 8:840-7. 2009
    ..All fermented milk products showed post-fermentation acidification after 24 h of storage at 4 degrees C; they remained stable after one week of storage...
  64. ncbi In vitro competitive adhesion and production of antagonistic compounds by lactic acid bacteria against fish pathogens
    José Luis Balcázar
    Laboratory of Fish Pathology, Faculty of Veterinary Sciences, University of Zaragoza, Zaragoza, Spain
    Vet Microbiol 122:373-80. 2007
    ....
  65. pmc Liver abscess and empyema due to Lactococcus lactis cremoris
    Hye Sook Kim
    Division of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea
    J Korean Med Sci 25:1669-71. 2010
    b>Lactococcus lactis cremoris infections are very rare in humans. We experienced liver abscess and empyema due to L. lactis cremoris in an immunocompetent adult. A 42-yr-old man was admitted with fever and abdominal pain...
  66. doi Chemical synthesis and biological evaluation of gallidermin-siderophore conjugates
    Sabesan Yoganathan
    Department of Chemistry, Gunning Lemieux Chemistry Centre, University of Alberta, Edmonton, Alberta T6G 2G2, Canada
    Org Biomol Chem 9:2133-41. 2011
    ..As there are many lantibiotics that operate with unknown mechanisms of action, this chemical approach provides a means to modify such peptides with biomarkers for biological investigations...
  67. doi Construction of two Lactococcus lactis expression vectors combining the Gateway and the NIsin Controlled Expression systems
    Francois P Douillard
    Department of Microbiology, University College Cork, Western Road, Cork, Ireland
    Plasmid 66:129-35. 2011
    ..lactis NICE expression vectors which integrate the Gateway cloning technology and which are suitable for the production of sufficient amounts of proteins to facilitate subsequent structural and functional analyses...
  68. pmc Time-resolved determination of the CcpA regulon of Lactococcus lactis subsp. cremoris MG1363
    Aldert L Zomer
    Department of Molecular Genetics, University of Groningen, Groningen Biomolecular Sciences and Biotechnology Institute, 9750 AA Haren, The Netherlands
    J Bacteriol 189:1366-81. 2007
    ....
  69. ncbi Dominant lactic acid bacteria and their technological properties isolated from the Himalayan ethnic fermented milk products
    Sailendra Dewan
    Food Microbiology Laboratory, Department of Botany, Sikkim Government College, Gangtok, 737102 Sikkim, India
    Antonie Van Leeuwenhoek 92:343-52. 2007
    ..This paper is the first report on functional lactic acid bacterial composition in some lesser-known ethnic fermented milk products of the Himalayas...
  70. ncbi Temperate phages TP901-1 and phiLC3, belonging to the P335 species, apparently use different pathways for DNA injection in Lactococcus lactis subsp. cremoris 3107
    Solvej Ostergaard Breum
    Department of Food Science, Faculty of Life Science, Copenhagen University, Frederiksberg, Denmark
    FEMS Microbiol Lett 276:156-64. 2007
    ..As such impairment was not seen when infecting E119, E121 and E126 with phiLC3, we conclude that TP901-1 and phiLC3 either are differently triggered by their receptor or utilize different pathways of injection...
  71. doi Intraspecific and interspecific interactions among proteins regulating exopolysaccharide synthesis in Streptococcus thermophilus, Streptococcus iniae, and Lactococcus lactis subsp. cremoris and the assessment of potential lateral gene transfer
    Angela D Cefalo
    Department of Biology, Utah State University, Logan, UT 84322, USA
    Can J Microbiol 57:1002-15. 2011
    ....
  72. doi Microbiological quality of fermented milk produced by repeated-batch culture
    Kiyohiko Nakasaki
    Department of Material Sciences and Chemical Engineering, Shizuoka University, Hamamatsu, Japan
    J Biosci Bioeng 105:73-6. 2008
    ..E. coli was washed out with the progress of the repeated-batch culture, and thus showed no adverse effects on the fermented-milk production...
  73. doi Lactococcus lactis subsp. tructae subsp. nov. isolated from the intestinal mucus of brown trout (Salmo trutta) and rainbow trout (Oncorhynchus mykiss)
    Tania Pérez
    Laboratory of Fish Pathology, Faculty of Veterinary Sciences, Universidad de Zaragoza, 50013 Zaragoza, Spain
    Int J Syst Evol Microbiol 61:1894-8. 2011
    ..The strains isolated in this study represent a new subspecies, for which the name Lactococcus lactis subsp. tructae subsp. nov. is proposed. The type strain is L105(T) ( = LMG 24662(T)  = DSM 21502(T))...
  74. doi Evaluation of the genetic polymorphism among Lactococcus lactis subsp. cremoris strains using comparative genomic hybridization and multilocus sequence analysis
    Amel Taïbi
    STELA Dairy Research Centre, Institute of Nutraceuticals and Functional Foods, Pavillon des Services, Universite Laval, Quebec, QC, Canada
    Int J Food Microbiol 144:20-8. 2010
    ..By selecting strains according to their genetic profiles, compatible and complementary mixed starters can be formulated, opening new avenues for industrial applications...
  75. ncbi Nonidentity between plasmid and chromosomal copies of ISS1-like sequences in Lactococcus lactis subsp. lactis CNRZ270 and their possible role in chromosomal integration of plasmid genes
    D C Huang
    Laboratoire de Genetique Microbienne, Universite de Caen, France
    Gene 118:39-46. 1992
    ..ISS1-like sequences were also found on plasmids of numerous Lc. lactis strains, as well as one out of seven Lactobacillus (Lb.) casei and one out of three Lb. plantarum strains examined...
  76. pmc Tripeptidase gene (pepT) of Lactococcus lactis: molecular cloning and nucleotide sequencing of pepT and construction of a chromosomal deletion mutant
    I Mierau
    Department of Genetics, University of Groningen, Haren, The Netherlands
    J Bacteriol 176:2854-61. 1994
    ..lactis was constructed. No differences between the growth of the mutant and that of the wild-type strain in milk or in chemically defined medium with casein as the sole source of essential amino acids were observed...
  77. pmc Analysis of a region from the bacteriophage resistance plasmid pCI528 involved in its conjugative mobilization between Lactococcus strains
    M Lucey
    Department of Food Microbiology, University College Cork, Ireland
    J Bacteriol 175:6002-9. 1993
    ..4 kb-segment revealed a region rich in inverted repeats and two potential overlapping open reading frames, one of which demonstrated homology to mobilization proteins of two nonconjugative staphylococcal plasmids...
  78. ncbi Nucleotide sequence and analysis of pWC1, a pC194-type rolling circle replicon in Lactococcus lactis
    C J Pillidge
    NZ Dairy Research Institute, Palmerston North, New Zealand
    Plasmid 35:131-40. 1996
    ..The pWC1 replicon may be a useful addition to other replicons currently available for vector construction...
  79. ncbi Identification and sequence analysis of IS1297, an ISS1-like insertion sequence in a Leuconostoc strain
    L J Ward
    New Zealand Dairy Research Institute, Palmerston North, New Zealand
    Gene 174:259-63. 1996
    ..This is the first sequence of an ISS1-like element from a genus other than Lactococcus; however, IS1297 has close similarity to the lactococcal iso-ISS1 elements, especially the iso-ISS1 element from the lactose plasmid, pTD1...
  80. ncbi Genetic analysis of regions involved in replication and cadmium resistance of the plasmid pND302 from Lactococcus lactis
    C Q Liu
    Department of Biotechnology, University of New South Wales, Sydney, Australia
    Plasmid 38:79-90. 1997
    ..Similar CdR determinants were also detected by PCR in other CdR plasmids isolated from different L. lactis strains...
  81. ncbi Nucleotide sequence and analysis of the new chromosomal abortive infection gene abiN of Lactococcus lactis subsp. cremoris S114
    F Prevots
    Faculte de Pharmacie, Toulouse, France
    FEMS Microbiol Lett 159:331-6. 1998
    ..63. No homology with any previously described genes was found. A probe was used to determine the presence of this gene only in S114 from 31 strains tested...
  82. pmc Lysis of Lactococcus lactis subsp. cremoris SK110 and its nisin-immune transconjugant in relation to flavor development in cheese
    W Meijer
    Flavour and Starters Section, Netherlands Institute for Dairy Research NIZO, Ede, The Netherlands
    Appl Environ Microbiol 64:1950-3. 1998
    ....
  83. ncbi Determination of the recognition sequence of the type II restriction endonuclease, LlaCI, from Lactococcus lactis W15
    J Josephsen
    Department of Dairy and Food Science, Royal Veterinary and Agricultural University, Frederiksberg, Denmark
    FEMS Microbiol Lett 163:25-9. 1998
    ..cremoris W15. The characterisation of the LlaCI endonuclease showed it to be an isoschizomer of HindIII, recognising the sequence 5-'A decreases AGCTT-3'. The cleavage site is indicated by the arrow...
  84. ncbi The majority of lactococcal plasmids carry a highly related replicon
    J F Seegers
    Department of Genetics, Centre of Biological Sciences, Haren, The Netherlands
    Microbiology 140:1291-300. 1994
    ..Southern hybridizations revealed that many lactococcal strains contain plasmids of this family...
  85. ncbi Purification and characterization of an endopeptidase from Lactococcus lactis subsp. cremoris SK11
    G G Pritchard
    Department of Chemistry and Biochemistry, Massey University, Palmerston North, New Zealand
    Microbiology 140:923-30. 1994
    ..These observations argue against a role for this enzyme in the early stages of casein breakdown by the lactococcal proteolytic system...
  86. pmc Phage abortive infection mechanism from Lactococcus lactis subsp. lactis, expression of which is mediated by an Iso-ISS1 element
    P J Cluzel
    Laboratoire de Genetique Microbienne, Institut de Biotechnologie, I N R A, Jouy en Josas, France
    Appl Environ Microbiol 57:3547-51. 1991
    ..The expression of abi-416 was shown to be mediated by the Iso-ISS1 element, which contains a sequence fitting the consensus sequence for gram-positive promoters...
  87. pmc Characterization of phiLC3, a Lactococcus lactis subsp. cremoris temperature bacteriophage with cohesive single-stranded DNA ends
    D Lillehaug
    Laboratory of Microbial Gene Technology, Oslo, Norway
    Appl Environ Microbiol 57:3206-11. 1991
    ..This result indicates that lysogeny involves integration of the phage into the host chromosome. A spontaneous phiLC3 clear plaque mutant that was unable to give rise to lysogens was isolated...
  88. pmc Organization and nucleotide sequences of two lactococcal bacteriocin operons
    M J van Belkum
    Department of Genetics, University of Groningen, Haren, The Netherlands
    Appl Environ Microbiol 57:492-8. 1991
    ..The second ORF, containing 98 codons, specified immunity. The nucleotide sequences of both fragments upstream of the first ORFs as well as the first 20 bp of the first ORF of both bacteriocin operons appeared to be identical...
  89. pmc Lactococcal proteinase maturation protein PrtM is a lipoprotein
    A J Haandrikman
    Department of Genetics, University of Groningen, Haren, The Netherlands
    J Bacteriol 173:4517-25. 1991
    ..This mutation did not affect proteinase activity...
  90. pmc Molecular characterization of promoters of the Lactococcus lactis subsp. cremoris temperate bacteriophage BK5-T and identification of a phage gene implicated in the regulation of promoter activity
    G Lakshmidevi
    Russell Grimwade School of Biochemistry, University of Melbourne, Parkville, Victoria, Australia
    Appl Environ Microbiol 56:934-42. 1990
    ..This region has been designated bpi (for BK5-T promoter inhibitor)...
  91. pmc Nucleotide sequence of the cell wall proteinase gene of Streptococcus cremoris Wg2
    J Kok
    Institute of Genetics, University of Groningen, Haren, The Netherlands
    Appl Environ Microbiol 54:231-8. 1988
    A 6.5-kilobase HindIII fragment that specifies the proteolytic activity of Streptococcus cremoris Wg2 was sequenced entirely...
  92. ncbi Citrate utilization gene cluster of the Lactococcus lactis biovar diacetylactis: organization and regulation of expression
    F Lopez de Felipe
    Centro de Investigaciones Biologicas, C S I C, Velazquez, Madrid, Spain
    Mol Gen Genet 246:590-9. 1995
    ..We propose that expression of the cit cluster is controlled at the post-transcriptional level by mRNA processing at a putative complex secondary structure and by translational repression mediated by CitR...
  93. pmc Cloning and characterization of upp, a gene encoding uracil phosphoribosyltransferase from Lactococcus lactis
    J Martinussen
    Center for Lactic Acid Bacteria, Laboratory of Microbiology, Technical University of Denmark, Lyngby
    J Bacteriol 176:6457-63. 1994
    ..Secondary mutants in thymidine phosphorylase and thymidine kinase were isolated by selection for resistance to high concentrations of 5-fluorouracil...
  94. pmc Molecular characterization of the Lactococcus lactis LlaKR2I restriction-modification system and effect of an IS982 element positioned between the restriction and modification genes
    D P Twomey
    Department of Food Science and Nutrition, University of Minnesota, St Paul, Minnesota 55108, USA
    J Bacteriol 180:5844-54. 1998
    ....
  95. ncbi Molecular characterization of the lactococcal plasmid pCIS3: natural stacking of specificity subunits of a type I restriction/modification system in a single lactococcal strain
    J F Seegers
    National Food Biotechnology Centre, University College Cork, Ireland
    Microbiology 146:435-43. 2000
    ..The replication region of pCIS3 was highly similar to that of a large family of lactococcal theta replicons. In addition, pCIS3 was found to encode a member of the CorA family of magnesium transporters...
  96. pmc Structural changes and interactions involved in the Ca(2+)-triggered stabilization of the cell-bound cell envelope proteinase in Lactococcus lactis subsp. cremoris SK11
    F A Exterkate
    Department of Flavour and Natural Ingredients, NIZO Food Research, 6710 BA Ede, The Netherlands
    Appl Environ Microbiol 66:2021-8. 2000
    ..The conditions in cheese seem to confer stability upon the cell-bound enzyme; its possible involvement in proteolysis throughout the ripening period is discussed...
  97. ncbi [Cloning and structure analysis of a restriction and modification system, LlaBIII from Lactococcus lactis subsp. cremoris W56]
    J Kong
    State Key Laboratory of Microbial Technology, Shandong University, Jinan 250100, China
    Sheng Wu Gong Cheng Xue Bao 17:663-8. 2001
    ..Therefore, this polypeptide encoded by LlaBIII is a multifunctional protein possessing putative DNA recognition, methylation and restriction activities...
  98. ncbi Application of RAPD analysis for identification of Lactococcus lactis subsp. cremoris strains isolated from artisanal cultures
    D Samarzija
    Dairy Department, Faculty of Agriculture, University of Zagreb, Croatia
    Microbiol Res 157:13-7. 2002
    ..The results indicate that RAPD analysis could be a useful and efficient method to distinguish Lactococcus lactis subsp. cremoris at the strain level and to detect genetic diversity...
  99. pmc Characterization of the two-component abortive phage infection mechanism AbiT from Lactococcus lactis
    Julie D Bouchard
    Department of Biochemistry and Microbiology, Faculte des sciences et de genie, Groupe de Recherche en Ecologie Buccale, Faculte de Medecine Dentaire, Universite Laval, Quebec, Canada G1K 7P4
    J Bacteriol 184:6325-32. 2002
    ....
  100. pmc Use of real-time quantitative PCR for the analysis of phiLC3 prophage stability in lactococci
    Merete Lunde
    Laboratory of Microbial Gene Technology, Department of Chemistry and Biotechnology, Agricultural University of Norway, N 1432 Aas, Norway
    Appl Environ Microbiol 69:41-8. 2003
    ..The present study shows the power of the real-time PCR technique in the analysis of temperate phage biology and will be useful in work to reveal the impact of temperate phages and lysogenic bacteria in various ecological fields...
  101. ncbi Sequence and analysis of pBM02, a novel RCR cryptic plasmid from Lactococcus lactis subsp cremoris P8-2-47
    Claudia Sánchez
    Instituto de Productos Lácteos de Asturias CSIC, Carretera de Infiesto s n, 33300 Villaviciosa, Asturias, Spain
    Plasmid 49:118-29. 2003
    ..The replicon of pBM02 is of the wide-host range type, and functions in both Gram-positive and Gram-negative bacteria, including Lactobacillus casei, Lactobacillus plantarum, Bacillus subtilis, and Escherichia coli...