Babesia bigemina

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Top Publications

  1. Kumar N, Solanki J, Varghese A, Jadav M, Das B, Patel M, et al. Molecular Assessment of Anaplasma marginale in Bovine and Rhipicephalus (Boophilus) microplus Tick of Endemic Tribal Belt of Coastal South Gujarat, India. Acta Parasitol. 2019;: pubmed publisher
    ..parasites/µl of blood in sensitivity experiment, and observed 100% specificity against Trypanosoma evansi, Babesia bigemina and Theileria annulata. Prevalence rate of the A. marginale in the bovine (n = 211)) was 18.48% and 6...
  2. Gunasekara E, Sivakumar T, Kothalawala H, Abeysekera T, Weerasingha A, Vimalakumar S, et al. Epidemiological survey of hemoprotozoan parasites in cattle from low-country wet zone in Sri Lanka. Parasitol Int. 2019;71:5-10 pubmed publisher
    ..a coastal district located in low-country wet zone in Sri Lanka, and were PCR-screened for Babesia bovis, Babesia bigemina, T. annulata, T. orientalis, and Trypanosoma theileri. All the parasite species, except B...
  3. Giglioti R, Bassetto C, Okino C, de Oliveira H, de Sena Oliveira M. Development of a loop-mediated isothermal amplification (LAMP) assay for the detection of Anaplasma marginale. Exp Appl Acarol. 2019;77:65-72 pubmed publisher
    ..DNA from six cattle and hemoparasite samples (Babesia bovis, Babesia bigemina, Anaplasma centrale and A. marginale) were tested for specificity, sensitivity and cross-reactions...
  4. Suarez C, Alzan H, Silva M, Rathinasamy V, Poole W, Cooke B. Unravelling the cellular and molecular pathogenesis of bovine babesiosis: is the sky the limit?. Int J Parasitol. 2019;49:183-197 pubmed publisher
    The global impact of bovine babesiosis caused by the tick-borne apicomplexan parasites Babesia bovis, Babesia bigemina and Babesia divergens is vastly underappreciated...
  5. Hector E, Elelu N, Ferrolho J, Couto J, Sanches G, Antunes S, et al. PCR detection of Ehrlichia ruminantium and Babesia bigemina in cattle from Kwara State, Nigeria: unexpected absence of infection. Parasitol Res. 2019;118:1025-1029 pubmed publisher
    ..most significant TBDs of cattle in Africa are heartwater and babesioisis, caused by Ehrlichia ruminantium and Babesia bigemina respectively. Both pathogens are endemic in Nigeria...
  6. Mtshali M, Mtshali P. Molecular diagnosis and phylogenetic analysis of Babesia bigemina and Babesia bovis hemoparasites from cattle in South Africa. BMC Vet Res. 2013;9:154 pubmed publisher
    ..It was also noted that the situation of Babesia parasitic infection in cattle from certain areas within the surveyed provinces had either reached endemic stability or was progressing towards stability. ..
  7. Obregón D, Cabezas Cruz A, Armas Y, Silva J, Fonseca A, André M, et al. High co-infection rates of Babesia bovis, Babesia bigemina, and Anaplasma marginale in water buffalo in Western Cuba. Parasitol Res. 2019;118:955-967 pubmed publisher
    ..In this study, the prevalence of Babesia bovis, Babesia bigemina, and Anaplasma marginale were determined in water buffalo herds of western Cuba...
  8. Zanet S, Trisciuoglio A, Bottero E, de Mera I, Gortazar C, Carpignano M, et al. Piroplasmosis in wildlife: Babesia and Theileria affecting free-ranging ungulates and carnivores in the Italian Alps. Parasit Vectors. 2014;7:70 pubmed publisher
    ..capreoli as the most prevalent piroplasmid found in Alpine chamois, Roe deer and Red deer, followed by Babesia bigemina (found in Roe deer, Red deer and Wild boar), and the zoonotic Babesia venatorum (formerly Babesia sp...
  9. El Sayed S, Rizk M, Yokoyama N, Igarashi I. Evaluation of the in vitro and in vivo inhibitory effect of thymoquinone on piroplasm parasites. Parasit Vectors. 2019;12:37 pubmed publisher
    ..41 ± 3.60, 7.35 ± 0.17, 0.28 ± 0.016, 74.05 ± 4.55 and 67.33 ± 0.94 μM for Babesia bovis, Babesia bigemina, Babesia divergens, Theileria equi and Babesia caballi, respectively...

More Information

Publications75

  1. Pradeep R, Nimisha M, Sruthi M, Vidya P, Amrutha B, Kurbet P, et al. Molecular characterization of South Indian field isolates of bovine Babesia spp. and Anaplasma spp. Parasitol Res. 2019;118:617-630 pubmed publisher
    ..circulating in the blood of infected cattle viz., Babesia bigemina and a Babesia sp. genetically related to Babesia ovata...
  2. Sivakumar T, Tuvshintulga B, Zhyldyz A, Kothalawala H, Yapa P, Kanagaratnam R, et al. Genetic Analysis of Babesia Isolates from Cattle with Clinical Babesiosis in Sri Lanka. J Clin Microbiol. 2018;56: pubmed publisher
    ..These DNA samples tested positive in PCR assays specific for Babesia bovis (n = 9), Babesia bigemina (n = 9), and Babesia ovata (n = 1). Twelve cattle were positive for B...
  3. Ringo A, Adjou Moumouni P, Lee S, Liu M, Khamis Y, Gao Y, et al. Molecular detection and characterization of tick-borne protozoan and rickettsial pathogens isolated from cattle on Pemba Island, Tanzania. Ticks Tick Borne Dis. 2018;9:1437-1445 pubmed publisher
    ..PCR screening revealed overall infection rates of 62.4% for Theileria spp., 17.6% for Babesia bigemina, 15.9% for Anaplasma marginale, 7.4% for Ehrlichia ruminantium and 4.5% for Babesia bovis...
  4. Jaimes Dueñez J, Triana Chavez O, Holguín Rocha A, Tobón Castaño A, Mejia Jaramillo A. Molecular surveillance and phylogenetic traits of Babesia bigemina and Babesia bovis in cattle (Bos taurus) and water buffaloes (Bubalus bubalis) from Colombia. Parasit Vectors. 2018;11:510 pubmed publisher
    b>Babesia bigemina and B. bovis are two economically important hemoparasites affecting both cattle and buffaloes involved in dairy and beef production...
  5. Bohaliga G, Johnson W, Taus N, Hussein H, Bastos R, Suarez C, et al. Identification of a putative methyltransferase gene of Babesia bigemina as a novel molecular biomarker uniquely expressed in parasite tick stages. Parasit Vectors. 2018;11:480 pubmed publisher
    ..Together, these tools will facilitate our understanding of parasite-tick interactions, the identification of novel vaccine targets and, consequently, the development of additional strategies to control bovine babesiosis. ..
  6. Hassan M, Liu J, Rashid M, Iqbal N, Guan G, Yin H, et al. Molecular survey of piroplasm species from selected areas of China and Pakistan. Parasit Vectors. 2018;11:457 pubmed publisher
    ..amplified for species confirmation of Theileria-positive samples, whereas the RAP-1c gene was amplified for Babesia bigemina-positive samples. Semi-nested PCR results revealed that 144 (25.26%) samples were positive for piroplasms...
  7. Tian A, Elsheikha H, Zhou D, Wu Y, Chen M, Wang M, et al. A novel recombinase polymerase amplification (RPA) assay for the rapid isothermal detection of Neospora caninum in aborted bovine fetuses. Vet Parasitol. 2018;258:24-29 pubmed publisher
    ..Hammondia hammondi, Hammondia heydorni, Eimeria cylindrica, Plasmodium falciparum, Theileria annulata and Babesia bigemina). Although, LF-RPA assay detected amounts as low as 50 fg of N...
  8. El Ashker M, Hotzel H, Gwida M, El Beskawy M, Silaghi C, Tomaso H. Molecular biological identification of Babesia, Theileria, and Anaplasma species in cattle in Egypt using PCR assays, gene sequence analysis and a novel DNA microarray. Vet Parasitol. 2015;207:329-34 pubmed publisher
    ..The microarray chips identified Babesia bovis (n=12) and Babesia bigemina (n=2)...
  9. Aydin M, Aktas M, Dumanli N. Molecular identification of Theileria and Babesia in ticks collected from sheep and goats in the Black Sea region of Turkey. Parasitol Res. 2015;114:65-9 pubmed publisher
    ..02-9.02) in Rhipicephalus bursa. Pathogens identified in ticks included Theileria ovis, Babesia ovis, Babesia bigemina, and Babesia microti. Most tick pools were infected with a single pathogen...
  10. Silva M, Villarino N, Knowles D, Suarez C. Assessment of Draxxin® (tulathromycin) as an inhibitor of in vitro growth of Babesia bovis, Babesia bigemina and Theileria equi. Int J Parasitol Drugs Drug Resist. 2018;8:265-270 pubmed publisher
    Babesia bovis, Babesia bigemina and Theileria equi are worldwide tick-borne hemoprotozoan that cause diseases characterized by fever, anemia, weight loss and abortion...
  11. Toye P, Handel I, Gray J, Kiara H, Thumbi S, Jennings A, et al. Maternal antibody uptake, duration and influence on survival and growth rate in a cohort of indigenous calves in a smallholder farming system in western Kenya. Vet Immunol Immunopathol. 2013;155:129-34 pubmed publisher
    ..of life) were analysed for the presence of antibodies to four tick-borne haemoparasites: Anaplasma marginale, Babesia bigemina, Theileria mutans and Theileria parva. The analysis showed that at least 89...
  12. Guo J, Li M, Sun Y, Yu L, He P, Nie Z, et al. Characterization of a novel secretory spherical body protein in Babesia orientalis and Babesia orientalis-infected erythrocytes. Parasit Vectors. 2018;11:433 pubmed publisher
    ..The amino acid (aa) sequence of BoSBP4 was compared with that of Babesia bovis and Babesia bigemina as well as SBP3 of B. orientalis...
  13. Tayebwa D, Vudriko P, Tuvshintulga B, Guswanto A, Nugraha A, Gantuya S, et al. Molecular epidemiology of Babesia species, Theileria parva, and Anaplasma marginale infecting cattle and the tick control malpractices in Central and Eastern Uganda. Ticks Tick Borne Dis. 2018;9:1475-1483 pubmed publisher
    ..Nested PCR assays were performed to determine the prevalences of Babesia bovis, Babesia bigemina, Theileria parva, and Anaplasma marginale in cattle blood samples sourced from randomly selected farms...
  14. Giglioti R, de Oliveira H, Okino C, de Sena Oliveira M. qPCR estimates of Babesia bovis and Babesia bigemina infection levels in beef cattle and Rhipicephalus microplus larvae. Exp Appl Acarol. 2018;75:235-240 pubmed publisher
    ..58 and 0.66, respectively. These high positive correlation coefficients indicate that parasitemia load in the bovine may be dependent on or may determine the parasitemia load in the ticks. ..
  15. Antunes S, Merino O, Lérias J, Domingues N, Mosqueda J, de la Fuente J, et al. Artificial feeding of Rhipicephalus microplus female ticks with anti calreticulin serum do not influence tick and Babesia bigemina acquisition. Ticks Tick Borne Dis. 2015;6:47-55 pubmed publisher
    ..Rhipicephalus microplus and R. annulatus ticks are the most important vectors for Babesia bigemina and B...
  16. Elsify A, Sivakumar T, Nayel M, Salama A, Elkhtam A, Rizk M, et al. An epidemiological survey of bovine Babesia and Theileria parasites in cattle, buffaloes, and sheep in Egypt. Parasitol Int. 2015;64:79-85 pubmed publisher
    ..In this study, we analyzed the infection rates of Babesia bovis, Babesia bigemina, Theileria annulata, and Theileria orientalis, using parasite-specific PCR assays in blood-DNA samples ..
  17. Domingos A, Antunes S, Villar M, de la Fuente J. Functional genomics of tick vectors challenged with the cattle parasite Babesia bigemina. Methods Mol Biol. 2015;1247:475-89 pubmed publisher
    ..annulatus genes to determine their putative role in B. bigemina-tick interactions. Gathered data may be useful for the future development of improved vaccines and vaccination strategies to control babesiosis. ..
  18. De Clercq E, Leta S, Estrada Peña A, Madder M, Adehan S, Vanwambeke S. Species distribution modelling for Rhipicephalus microplus (Acari: Ixodidae) in Benin, West Africa: comparing datasets and modelling algorithms. Prev Vet Med. 2015;118:8-21 pubmed publisher
    Rhipicephalus microplus is one of the most widely distributed and economically important ticks, transmitting Babesia bigemina, B. bovis and Anaplasma marginale...
  19. Rodríguez Hernández E, Mosqueda J, León Ávila G, Castañeda Ortiz E, Álvarez Sánchez M, Camacho A, et al. BmVDAC upregulation in the midgut of Rhipicephalus microplus, during infection with Babesia bigemina. Vet Parasitol. 2015;212:368-74 pubmed publisher
    The molecular mechanisms involved during the infection of Rhipicephalus microplus midgut cells by Babesia bigemina are of great relevance and currently unknown...
  20. Hernández Silva D, Valdez Espinoza U, Mercado Uriostegui M, Aguilar Tipacamu G, Ramos Aragón J, Hernandez Ortiz R, et al. Immunomolecular Characterization of MIC-1, a Novel Antigen in Babesia bigemina, Which Contains Conserved and Immunodominant B-Cell Epitopes that Induce Neutralizing Antibodies. Vet Sci. 2018;5: pubmed publisher
    i>Babesia bigemina is one of the most prevalent species causing bovine babesiosis around the world. Antigens involved in host cell invasion are vaccine targets for this disease but are largely unknown in this species...
  21. Guo J, Hu J, Sun Y, Yu L, He J, He P, et al. A novel Babesia orientalis 135-kilodalton spherical body protein like: identification of its secretion into cytoplasm of infected erythrocytes. Parasit Vectors. 2018;11:205 pubmed publisher
    ..Four different SBP homologues (SBP1, SBP2, SBP3 and SBP4) have been identified in Babesia bovis and Babesia bigemina. So far, there has been no report available about the identification of SBPs in Babesia orientalis...
  22. Meetei P, Rathore R, Prabhu N, Vindal V. Modeling of babesipain-1 and identification of natural and synthetic leads for bovine babesiosis drug development. J Mol Model. 2016;22:71 pubmed publisher
    ..Recently, the cysteine protease enzyme, babesipain-1 from Babesia bigemina has been identified as a potential target for designing new anti-babesiosis drugs...
  23. Kusakisako K, Masatani T, Yada Y, Talactac M, Hernandez E, Maeda H, et al. Improvement of the cryopreservation method for the Babesia gibsoni parasite by using commercial freezing media. Parasitol Int. 2016;65:532-535 pubmed publisher
    ..and cryopreservation under liquid nitrogen have already been reported and established for Babesia bovis and Babesia bigemina parasites...
  24. Aktas M, Ozubek S. Molecular and Parasitological Survey of Bovine Piroplasms in the Black Sea Region, Including the First Report of Babesiosis Associated with Babesia divergens in Turkey. J Med Entomol. 2015;52:1344-50 pubmed publisher
    ..Parasitemia ranged from 0.08 to 0.9% for Babesia bovis, 2.5 to 15.4% for Babesia bigemina, and 7.4% for Babesia divergens...
  25. Romero Salas D, Mira A, Mosqueda J, García Vázquez Z, Hidalgo Ruiz M, Vela N, et al. Molecular and serological detection of Babesia bovis- and Babesia bigemina-infection in bovines and water buffaloes raised jointly in an endemic field. Vet Parasitol. 2016;217:101-7 pubmed publisher
    Babesia bovis and Babesia bigemina are causative agents of bovine babesiosis, a tick-borne disease of cattle in tropical and subtropical regions. Babesia spp...
  26. Zhou M, Cao S, Sevinc F, Sevinc M, Ceylan O, Moumouni P, et al. Molecular detection and genetic identification of Babesia bigemina, Theileria annulata, Theileria orientalis and Anaplasma marginale in Turkey. Ticks Tick Borne Dis. 2016;7:126-134 pubmed publisher
    ..In this study, we investigated the presence and distribution of Babesia bigemina, Theileria annulata, Theileria orientalis and Anaplasma marginale in cattle from 6 provinces of Turkey using ..
  27. Liyanagunawardena N, Sivakumar T, Kothalawala H, Silva S, Battsetseg B, Lan D, et al. Type-specific PCR assays for Babesia bovis msa-1 genotypes in Asia: Revisiting the genetic diversity in Sri Lanka, Mongolia, and Vietnam. Infect Genet Evol. 2016;37:64-9 pubmed publisher
    ..Furthermore, no amplicons were observed by these PCR assays when DNA samples of Babesia bigemina, Babesia ovata, Theileria annulata, Theileria orientalis, Trypanosoma evansi, Trypanosoma theileri, Anaplasma ..
  28. Silva M, Knowles D, Mazuz M, Cooke B, Suarez C. Stable transformation of Babesia bigemina and Babesia bovis using a single transfection plasmid. Sci Rep. 2018;8:6096 pubmed publisher
    b>Babesia bigemina and Babesia bovis, are the two major causes of bovine babesiosis, a global neglected disease in need of improved methods of control...
  29. de Rezende J, Rangel C, McIntosh D, Silveira J, Cunha N, Ramos C, et al. In vitro cultivation and cryopreservation of Babesia bigemina sporokinetes in hemocytes of Rhipicephalus microplus. Vet Parasitol. 2015;212:400-3 pubmed publisher
    ..reports the development and evaluation of methods for the in vitro culture and maintenance of sporokinetes of Babesia bigemina in association with hemocytes of the tick Rhipicephalus microplus...
  30. André M, Herrera H, Fernandes S, de Sousa K, Gonçalves L, Domingos I, et al. Tick-borne agents in domesticated and stray cats from the city of Campo Grande, state of Mato Grosso do Sul, midwestern Brazil. Ticks Tick Borne Dis. 2015;6:779-86 pubmed publisher
    ..9%) for Babesia/Theileria (one sequence was closely related to Babesia bigemina, eight for Babesia vogeli, five to Theileria spp...
  31. Jirapattharasate C, Adjou Moumouni P, Cao S, Iguchi A, Liu M, Wang G, et al. Molecular epidemiology of bovine Babesia spp. and Theileria orientalis parasites in beef cattle from northern and northeastern Thailand. Parasitol Int. 2016;65:62-69 pubmed publisher
    ..In this study, we determined the prevalence of Babesia bigemina, Babesia bovis and Theileria orientalis using polymerase chain reaction (PCR)...
  32. Qin S, Wang J, Ning H, Tan Q, Yin M, Zhang X, et al. First report of Babesia bigemina infection in white yaks in China. Acta Trop. 2015;145:52-4 pubmed publisher
    ..However, there was no information on the prevalence of Babesia bigemina in white yaks...
  33. Silvestre B, Silveira J, Meneses R, Facury Filho E, Carvalho A, Ribeiro M. Identification of a vertically transmitted strain from Anaplasma marginale (UFMG3): Molecular and phylogenetic characterization, and evaluation of virulence. Ticks Tick Borne Dis. 2016;7:80-84 pubmed publisher
    ..marginale, Babesia bovis and Babesia bigemina. Calves positive for A...
  34. Adjou Moumouni P, Aboge G, Terkawi M, Masatani T, Cao S, Kamyingkird K, et al. Molecular detection and characterization of Babesia bovis, Babesia bigemina, Theileria species and Anaplasma marginale isolated from cattle in Kenya. Parasit Vectors. 2015;8:496 pubmed publisher
    Infections with Babesia bovis, Babesia bigemina, Theileria species and Anaplasma marginale are endemic in Kenya yet there is a lack of adequate information on their genotypes...
  35. Bautista Garfias C, Lozano A, Martínez C, Martínez J, Millán J, García G, et al. Co-immunization of cattle with a vaccine against babesiosis and Lactobacillus casei increases specific IgG1 levels to Babesia bovis and B. bigemina. Parasitol Int. 2015;64:319-23 pubmed publisher
    ..bovine babesiosis (VAC) on induction of IgG1 and IgG2 antibodies to Babesia bovis and Babesia bigemina was assessed by the indirect fluorescent antibody test (IFAT) in bovines of an endemic babesiosis area before ..
  36. Whitacre L, Tizioto P, Kim J, Sonstegard T, Schroeder S, Alexander L, et al. What's in your next-generation sequence data? An exploration of unmapped DNA and RNA sequence reads from the bovine reference individual. BMC Genomics. 2015;16:1114 pubmed publisher
    ..Most prominent were several species of Spirurid nematodes and a blood-borne parasite, Babesia bigemina. These species are either not present in the US or are not known to infect taurine cattle and the reference ..
  37. Bawm S, Htun L, Maw N, Ngwe T, Tosa Y, Kon T, et al. Molecular survey of Babesia infections in cattle from different areas of Myanmar. Ticks Tick Borne Dis. 2016;7:204-207 pubmed publisher
    ..Nested PCR assays based on the Babesia bigemina apical membrane antigen-1 gene (AMA-1) and B...
  38. Laha R, Mondal B, Biswas S, Chand K, Das M, Sarma D, et al. Detection of Babesia bigemina infection in cattle from north-eastern India by polymerase chain reaction and its genetic relatedness with other isolates. Trop Anim Health Prod. 2015;47:633-6 pubmed publisher
    ..All the samples were examined for diagnosis of Babesia bigemina infection using PCR for detection of specific DNA. Out of these, 12 (3.60%) samples were found positive for B...
  39. Omar Abdallah M, Niu Q, Yu P, Guan G, Yang J, Chen Z, et al. Identification of piroplasm infection in questing ticks by RLB: a broad range extension of tick-borne piroplasm in China?. Parasitol Res. 2016;115:2035-44 pubmed publisher
    ..found to infect with 89 tick samples in four tick species; no infections with Babesia major, Babesia ovata, Babesia bigemina, Theileria sergenti, or Theileria equi were detected...
  40. Yang Y, Li Q, Wang S, Chen X, Du A. Rapid and sensitive detection of Babesia bovis and Babesia bigemina by loop-mediated isothermal amplification combined with a lateral flow dipstick. Vet Parasitol. 2016;219:71-6 pubmed publisher
    ..Bovine babesiosis mainly caused by Babesia bovis and Babesia bigemina occurs worldwide, which is a great threat to animal health...
  41. Molad T, Erster O, Fleiderovitz L, Roth A, Leibovitz B, Wolkomirsky R, et al. Molecular characterization of the Israeli B. bigemina vaccine strain and field isolates. Vet Parasitol. 2015;212:147-55 pubmed publisher
    The present study demonstrated the genetic character of the Israeli Babesia bigemina vaccine strain and field isolates, based on rap-1a and rap-1c gene sequences. The RAP-1a of blood-derived Israeli B...
  42. Omar M, Salama A, Elsify A, Rizk M, Al Aboody M, Aboulaila M, et al. Evaluation of in vitro inhibitory effect of enoxacin on Babesia and Theileria parasites. Exp Parasitol. 2016;161:62-7 pubmed publisher
    ..5, 15.2, 7.5 and 23.2 μM for Babesia bovis, Babesia bigemina, Babesia caballi, and Theileria equi, respectively)...
  43. Niu Q, Liu Z, Yu P, Yang J, Abdallah M, Guan G, et al. Genetic characterization and molecular survey of Babesia bovis, Babesia bigemina and Babesia ovata in cattle, dairy cattle and yaks in China. Parasit Vectors. 2015;8:518 pubmed publisher
    ..The data obtained in this study can be used to plan effective control strategies against babesiosis in China. ..
  44. G Silva M, Knowles D, Antunes S, Domingos A, Esteves M, Suarez C. Inhibition of the in vitro growth of Babesia bigemina, Babesia caballi and Theileria equi parasites by trifluralin analogues. Ticks Tick Borne Dis. 2017;8:593-597 pubmed publisher
    Bovine and equine babesiosis caused by Babesia bovis, Babesia bigemina and Babesia caballi, along with equine theileriosis caused by Theileria equi are global tick-borne hemoprotozoan diseases characterized by fever, anemia, weight losses ..
  45. Munkhjargal T, Aboge G, Ueno A, Aboulaila M, Yokoyama N, Igarashi I. Identification and characterization of profilin antigen among Babesia species as a common vaccine candidate against babesiosis. Exp Parasitol. 2016;166:29-36 pubmed publisher
    ..bovis), Babesia bigemina (B. bigemina), and Babesia microti (B...
  46. Lorusso V, Wijnveld M, Majekodunmi A, Dongkum C, Fajinmi A, Dogo A, et al. Tick-borne pathogens of zoonotic and veterinary importance in Nigerian cattle. Parasit Vectors. 2016;9:217 pubmed publisher
    ..4%), Theileria taurotragi (39.5%), Anaplasma marginale (39.1%), Anaplasma sp. (Omatjenne) (34.7%), Babesia bigemina (7.9%), Anaplasma centrale (6.3%), Anaplasma platys (3.9%), Rickettsia massiliae (3.5%), Babesia bovis (2...
  47. Wesonga F, Gachohi J, Kitala P, Gathuma J, Njenga M. Seroprevalence of Anaplasma marginale and Babesia bigemina infections and associated risk factors in Machakos County, Kenya. Trop Anim Health Prod. 2017;49:265-272 pubmed publisher
    Anaplasma marginale and Babesia bigemina are important tick-borne pathogens of cattle. A cross-sectional survey was undertaken to determine the seroprevalence of A. marginale and B...
  48. Horak I, Heyne H, Halajian A, Booysen S, Smit W. Parasites of domestic and wild animals in South Africa. L. Ixodid ticks infesting horses and donkeys. Onderstepoort J Vet Res. 2017;84:e1-e6 pubmed publisher
    ..Amblyomma hebraeum is the vector of Ehrlichia ruminantium, the causative organism of heartwater in cattle, sheep and goats, whereas R. decoloratus transmits Babesia bigemina, the causative organism of babesiosis in cattle.
  49. Jackson A, Otto T, Darby A, Ramaprasad A, Xia D, Echaide I, et al. The evolutionary dynamics of variant antigen genes in Babesia reveal a history of genomic innovation underlying host-parasite interaction. Nucleic Acids Res. 2014;42:7113-31 pubmed publisher
    ..Hence, VESA2 proteins are abundant and previously unrecognized elements of Babesia biology, with evolutionary dynamics consistently different to those of VESA1, suggesting that their functions are distinct. ..
  50. Doyle R, Da Silva A, Oliveira C, França R, Carvalho F, Abdalla F, et al. Cholinesterases as markers of the inflammatory process associated oxidative stress in cattle infected by Babesia bigemina. Comp Immunol Microbiol Infect Dis. 2016;46:1-6 pubmed publisher
    The objective of this study was to assess the influence of an asymptomatic experimental infection by Babesia bigemina on cholinesterase's as markers of the inflammatory process and biomarkers of oxidative imbalance...
  51. Silveira J, de Oliveira C, Silvestre B, Albernaz T, Leite R, Barbosa J, et al. Molecular assays reveal the presence of Theileria spp. and Babesia spp. in Asian water buffaloes (Bubalus bubalis, Linnaeus, 1758) in the Amazon region of Brazil. Ticks Tick Borne Dis. 2016;7:1017-1023 pubmed publisher
    ..2% (13/308) for Theileria spp., 3.6% (11/308) for Babesia bovis and 1% (3/308) for Babesia bigemina. Animals infected with Theileria were detected in 50% (3/6) of the assessed properties...
  52. Silva M, Knowles D, Suarez C. Identification of interchangeable cross-species function of elongation factor-1 alpha promoters in Babesia bigemina and Babesia bovis. Parasit Vectors. 2016;9:576 pubmed
    Tick-borne Babesia bigemina is responsible for acute and potentially lethal hemolytic disease in cattle...
  53. Jirapattharasate C, Adjou Moumouni P, Cao S, Iguchi A, Liu M, Wang G, et al. Molecular detection and genetic diversity of bovine Babesia spp., Theileria orientalis, and Anaplasma marginale in beef cattle in Thailand. Parasitol Res. 2017;116:751-762 pubmed publisher
    ..In this study, we used PCR to detect the presence of Babesia bovis, Babesia bigemina, and T. orientalis in 279 beef cattle from Western Thailand and A...
  54. Giglioti R, Oliveira H, Santana C, Ibelli A, Néo T, Bilhassi T, et al. Babesia bovis and Babesia bigemina infection levels estimated by qPCR in Angus cattle from an endemic area of São Paulo state, Brazil. Ticks Tick Borne Dis. 2016;7:657-662 pubmed publisher
    The levels of infection by Babesia bovis and Babesia bigemina were estimated by absolute quantification through the quantitative PCR technique (qPCR). Fifty-one contemporaneous Angus cattle were evaluated on two occasions...
  55. Alhaboubi A, He L, McCormack K, Gustafson A, Holman P. Recovery of bovine Babesia spp. after long-term cryostorage and comparison of bovine donor erythrocytes and serum. Vet Parasitol. 2017;243:109-114 pubmed publisher
    Cultured Babesia bovis and Babesia bigemina were recovered from liquid nitrogen storage nearly 30 years after they were cryopreserved...
  56. Rizk M, El Sayed S, Aboulaila M, Yokoyama N, Igarashi I. Evaluation of the inhibitory effect of N-acetyl-L-cysteine on Babesia and Theileria parasites. Exp Parasitol. 2017;179:43-48 pubmed publisher
    ..The in vitro growth of Babesia bovis, Babesia bigemina, Babesia divergens, Theileria equi, and Babesia caballi that were tested was significantly inhibited (P <..
  57. Guswanto A, Allamanda P, Mariamah E, Munkjargal T, Tuvshintulga B, Takemae H, et al. Evaluation of immunochromatographic test (ICT) strips for the serological detection of Babesia bovis and Babesia bigemina infection in cattle from Western Java, Indonesia. Vet Parasitol. 2017;239:76-79 pubmed publisher
    ..Furthermore, the data showed the current seroprevalence of bovine babesiosis in Western Java, Indonesia, and efficient control strategies are needed to reduce economic losses due to the disease. ..
  58. Terkawi M, Jia H, Gabriel A, Goo Y, Nishikawa Y, Yokoyama N, et al. A shared antigen among Babesia species: ribosomal phosphoprotein P0 as a universal babesial vaccine candidate. Parasitol Res. 2007;102:35-40 pubmed publisher
    ..The P0 genes from Babesia caballi, Babesia equi, and Babesia bigemina were then cloned and sequenced...
  59. Roy B, Krucken J, Ahmed J, Majumder S, Baumann M, Clausen P, et al. Molecular identification of tick-borne pathogens infecting cattle in Mymensingh district of Bangladesh reveals emerging species of Anaplasma and Babesia. Transbound Emerg Dis. 2017;: pubmed publisher
    ..2%) followed by infections with Anaplasma bovis (137/384, 35.67%), Anaplasma marginale (16/384, 4.17%), Babesia bigemina (4/384, 1.04%) and Babesia bovis (2/384, 0.52%). A previously uncharacterized Anaplasma sp. (Anaplasma sp...
  60. de Sousa K, Fernandes M, Herrera H, Freschi C, Machado R, André M. Diversity of piroplasmids among wild and domestic mammals and ectoparasites in Pantanal wetland, Brazil. Ticks Tick Borne Dis. 2018;9:245-253 pubmed publisher
    ..thous, one dog, one A. ovale and one A. sculptum, genotypes closely related to Babesia bigemina and Babesia bovis were detected in four A. parvum ticks. Four sequences obtained from A...
  61. Jaimes Dueñez J, Triana Chavez O, Mejia Jaramillo A. Parasitological and molecular surveys reveal high rates of infection with vector-borne pathogens and clinical anemia signs associated with infection in cattle from two important livestock areas in Colombia. Ticks Tick Borne Dis. 2017;8:290-299 pubmed publisher
    ..3%), 146 (31.5%), 64 (13.8%), 236 (50.9%) and 43 (9.3%) of the samples were positive for Anaplasma marginale, Babesia bigemina, Babesia bovis, Trypanosoma theileri and T. evansi, respectively. Mixed infections were detected in 250 (53...
  62. Sivakumar T, Lan D, Long P, Viet L, Weerasooriya G, Kume A, et al. Serological and molecular surveys of Babesia bovis and Babesia bigemina among native cattle and cattle imported from Thailand in Hue, Vietnam. J Vet Med Sci. 2017;: pubmed publisher
    ..Importing Babesia-infected cattle may lead to the introduction of new parasite strains, possibly compromising the development of anti-Babesia immune control strategies in Vietnam...
  63. Hailemariam Z, Krucken J, Baumann M, Ahmed J, Clausen P, Nijhof A. Molecular detection of tick-borne pathogens in cattle from Southwestern Ethiopia. PLoS ONE. 2017;12:e0188248 pubmed publisher
    ..1%), Theileria orientalis (51.8%), Anaplasma sp. Omatjenne (25.5%), Anaplasma marginale (14.5%), Babesia bigemina (14.0%) and Theileria velifera (13.0%) and minor occurrences of Ehrlichia ruminantium (0...
  64. Rojas Martínez C, Rodriguez Vivas R, Millán J, Bautista Garfias C, Castañeda Arriola R, Lira Amaya J, et al. Bovine babesiosis: Cattle protected in the field with a frozen vaccine containing Babesia bovis and Babesia bigemina cultured in vitro with a serum-free medium. Parasitol Int. 2018;67:190-195 pubmed publisher
    ..bigemina in GI and GII, and lower titers were determined in GIII. The protective capacity of the vaccine derived from B. bovis and B. bigemina cultured in vitro in a serum-free medium was demonstrated. ..
  65. Camacho Nuez M, Hernández Silva D, Castañeda Ortiz E, Paredes Martínez M, Rocha Martínez M, Alvarez Sánchez M, et al. Hap2, a novel gene in Babesia bigemina is expressed in tick stages, and specific antibodies block zygote formation. Parasit Vectors. 2017;10:568 pubmed publisher
    ..To isolate and sequence the hap2 gene DNA from an infected bovine with Babesia bigemina was purified. The hap2 gene was amplified, cloned and sequenced...
  66. Zhang B, Sambono J, Morgan J, Venus B, Rolls P, Lew Tabor A. An Evaluation of Quantitative PCR Assays (TaqMan® and SYBR Green) for the Detection of Babesia bigemina and Babesia bovis, and a Novel Fluorescent-ITS1-PCR Capillary Electrophoresis Method for Genotyping B. bovis Isolates. Vet Sci. 2016;3: pubmed publisher
    ..bovis are described. This assay is capable of detecting vaccine and novel field isolate alleles in a single sample. ..