Rickettsia prowazekii str. Madrid E

Summary

Alias: Rickettsia prowazekii 'Madrid E', Rickettsia prowazekii strain Madrid E

Top Publications

  1. Zhang J, Fan M, Wu Y, Fournier P, Roux V, Raoult D. Genetic classification of "Rickettsia heilongjiangii" and "Rickettsia hulinii," two Chinese spotted fever group rickettsiae. J Clin Microbiol. 2000;38:3498-501 pubmed
  2. Beninati T, Lo N, Noda H, Esposito F, Rizzoli A, Favia G, et al. First detection of spotted fever group rickettsiae in Ixodes ricinus from Italy. Emerg Infect Dis. 2002;8:983-6 pubmed
    ..Using molecular methods, we detected three different spotted fever group rickettsiae, including Rickettsia helvetica. Our results raise the possibility that bacteria other than R. conorii are involved in rickettsial diseases in Italy. ..
  3. Sekeyova Z, Fournier P, Rehacek J, Raoult D. Characterization of a new spotted fever group rickettsia detected in Ixodes ricinus (Acari: Ixodidae) collected in Slovakia. J Med Entomol. 2000;37:707-13 pubmed
  4. Whitworth T, Popov V, YU X, Walker D, Bouyer D. Expression of the Rickettsia prowazekii pld or tlyC gene in Salmonella enterica serovar Typhimurium mediates phagosomal escape. Infect Immun. 2005;73:6668-73 pubmed
    ..These data suggest a role for tlyC and pld in the process of phagosomal escape by R. prowazekii. ..
  5. Billings A, Teltow G, Weaver S, Walker D. Molecular characterization of a novel Rickettsia species from Ixodes scapularis in Texas. Emerg Infect Dis. 1998;4:305-9 pubmed
    ..australis for the 17 kDa gene, R. helvetica for gltA, and R. montana for rompA. The new organism, provisionally designated as genotype Cooleyi, is highly divergent in three conserved genes from recognized Rickettsia species. ..
  6. Housley N, Winkler H, Audia J. The Rickettsia prowazekii ExoU homologue possesses phospholipase A1 (PLA1), PLA2, and lyso-PLA2 activities and can function in the absence of any eukaryotic cofactors in vitro. J Bacteriol. 2011;193:4634-42 pubmed publisher
    ..prowazekii lysed cell extracts, thus verifying that this protein is expressed and active in rickettsiae isolated from embryonated hen egg yolk sacs...
  7. Sekeyova Z, Roux V, Raoult D. Phylogeny of Rickettsia spp. inferred by comparing sequences of 'gene D', which encodes an intracytoplasmic protein. Int J Syst Evol Microbiol. 2001;51:1353-60 pubmed publisher
    ..As significant bootstrap values were obtained for most of the nodes, sequence comparison of 'gene D' should be considered as a complementary approach in phylogenetic studies of rickettsiae...
  8. Marks G, Wood D. Characterization of the gene coding for the Rickettsia prowazekii DNA primase analogue. Gene. 1993;123:121-5 pubmed
    ..coli. The gene organization of an ORF followed by DNA primase (dnaG) and then the major sigma factor (rpoD) is consistent with the major macromolecular synthesis operons of E. coli, S. typhimurium and B. subtilis. ..
  9. Anderson B, Baumstark B, Bellini W. Nucleotide sequence of the P34 gene from Rickettsia rickettsii. Nucleic Acids Res. 1990;18:7168 pubmed

More Information

Publications81

  1. Anderson B, Baumstark B, Bellini W. Expression of the gene encoding the 17-kilodalton antigen from Rickettsia rickettsii: transcription and posttranslational modification. J Bacteriol. 1988;170:4493-500 pubmed
  2. Subramanian S, Abendroth J, Phan I, Olsen C, Staker B, Napuli A, et al. Structure of 3-ketoacyl-(acyl-carrier-protein) reductase from Rickettsia prowazekii at 2.25 Å resolution. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011;67:1118-22 pubmed publisher
    ..Hence, drugs known to target the enzymes of pathogenic bacteria may serve as potential leads against Rickettsia, which is responsible for spotted fever and typhus and is found throughout the world. ..
  3. Waite R, Shaw E, Winkler H, Wood D. Isolation and characterization of the dnaA gene of Rickettsia prowazekii. Acta Virol. 1998;42:95-101 pubmed
    ..In addition, gene organization within this region differed from that of other bacteria. The putative start of transcription of the rickettsial dnaA gene was localized to a site 522 nucleotides (nt) upstream of the DnaA start codon. ..
  4. Labruna M, Camargo L, Camargo E, Walker D. Detection of a spotted fever group Rickettsia in the tick Haemaphysalis juxtakochi in Rondonia, Brazil. Vet Parasitol. 2005;127:169-74 pubmed
    ..juxtakochi from the Western Amazon area of Brazil. Genetic analyses showed R300 to be closely related to R. rhipicephali. ..
  5. Marks G, Winkler H, Wood D. Isolation and characterization of the gene coding for the major sigma factor of Rickettsia prowazekii DNA-dependent RNA polymerase. Gene. 1992;121:155-60 pubmed
    ..Despite a similarity to the E. coli sigma 70 encoded by rpoD, R. prowazekii sigma 73 did not complement E. coli rpoD temperature-sensitive mutants. ..
  6. Plano G, Wood D, Winkler H. Rickettsia prowazekii and ATP/ADP translocase. Analysis of gene fusions encoding beta-galactosidase-ATP/ADP translocase fusion proteins. Ann N Y Acad Sci. 1990;590:397-407 pubmed
  7. Williamson L, Plano G, Winkler H, Krause D, Wood D. Nucleotide sequence of the Rickettsia prowazekii ATP/ADP translocase-encoding gene. Gene. 1989;80:269-78 pubmed
    ..The major protein synthesized in E. coli minicells containing the rickettsial gene exhibited and Mr of approx. 34,000. ..
  8. Phan I, Subramanian S, Olsen C, Edwards T, Guo W, Zhang Y, et al. Structure of fumarate hydratase from Rickettsia prowazekii, the agent of typhus and suspected relative of the mitochondria. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011;67:1123-8 pubmed publisher
    ..A structure alignment with human mitochondrial fumarate hydratase highlights the close similarity between R. prowazekii and mitochondrial enzymes. ..
  9. Marks G, Wood D. Nucleotide sequence of the Rickettsia prowazekii greA homolog. Nucleic Acids Res. 1992;20:3785 pubmed
  10. Wood D, Waite R. Sequence analysis of the Rickettsia prowazekii gyrA gene. Gene. 1994;151:191-6 pubmed
    ..coli gyrA temperature-sensitive mutant. However, Rp gyrA was dominant to an E. coli gyrA96 nalidixic-acid-resistant (NalR) mutant, conferring Nal sensitivity when introduced into the NalR E. coli strain. ..
  11. Dunkin S, Wood D. Isolation and characterization of the Rickettsia prowazekii recA gene. J Bacteriol. 1994;176:1777-81 pubmed
    ..The characterized region upstream of rickettsial recA did not contain a sequence homologous to an E. coli LexA binding site (SOS box), suggesting differences in the regulation of the R. prowazekii recA gene. ..
  12. Aliabadi Z, Winkler H, Wood D. Isolation and characterization of the Rickettsia prowazekii gene encoding the flavoprotein subunit of succinate dehydrogenase. Gene. 1993;133:135-40 pubmed
    ..coli sdhA mutant. In addition, analysis of the nt sequence immediately upstream from R. prowazekii sdhA revealed that the rickettsial sdh gene organization differs from that of E. coli and B. subtilis. ..
  13. Shaw E, Wood D. Characterization of a Rickettsia rickettsii DNA fragment analogous to the fir A-ORF17-lpxA region of Escherichia coli. Gene. 1994;140:109-13 pubmed
    ..coli and Salmonella typhimurium FirA/Ssc and E. coli LpxA, as well as other acyltransferases, providing additional support for the importance of this structure. ..
  14. Wood D, Solomon M, Speed R. Characterization of the Rickettsia prowazekii pepA gene encoding leucine aminopeptidase. J Bacteriol. 1993;175:159-65 pubmed
    ..coli PepA, the R. prowazekii protein was unable to complement the cer site-specific, PepA-dependent recombination system found in E. coli that resolves ColE1-type plasmid multimers into their monomeric forms. ..
  15. Anderson B, Regnery R, Carlone G, Tzianabos T, McDade J, Fu Z, et al. Sequence analysis of the 17-kilodalton-antigen gene from Rickettsia rickettsii. J Bacteriol. 1987;169:2385-90 pubmed
    ..The deduced amino acid sequence contained a hydrophobic sequence near the amino terminus that resembled signal peptides described for E. coli. The carboxy terminus was hydrophilic in nature and probably contained the exposed epitopes. ..
  16. Plano G, Winkler H. Identification and initial topological analysis of the Rickettsia prowazekii ATP/ADP translocase. J Bacteriol. 1991;173:3389-96 pubmed
    ..These data in conjunction with hydrophobicity analysis were used to construct an initial topological model of the translocase within the cell membrane. ..
  17. Baird R, Lloyd M, Stenos J, Ross B, Stewart R, Dwyer B. Characterization and comparison of Australian human spotted fever group rickettsiae. J Clin Microbiol. 1992;30:2896-902 pubmed
    ..Thus, the rickettsiae isolated from patients with FISF differ from those from patients with QTT and may represent a new rickettsial species. ..
  18. Chao C, Chelius D, Zhang T, Mutumanje E, Ching W. Insight into the virulence of Rickettsia prowazekii by proteomic analysis and comparison with an avirulent strain. Biochim Biophys Acta. 2007;1774:373-81 pubmed publisher
    ..This result suggests the possible relationship between this gene product and the virulence of the strains...
  19. Driskell L, YU X, Zhang L, Liu Y, Popov V, Walker D, et al. Directed mutagenesis of the Rickettsia prowazekii pld gene encoding phospholipase D. Infect Immun. 2009;77:3244-8 pubmed publisher
    ..This study demonstrates the feasibility of generating site-directed rickettsial gene mutants, providing a new tool for understanding rickettsial biology and furthering advances in the prevention of epidemic typhus...
  20. Hackstadt T, Messer R, Cieplak W, Peacock M. Evidence for proteolytic cleavage of the 120-kilodalton outer membrane protein of rickettsiae: identification of an avirulent mutant deficient in processing. Infect Immun. 1992;60:159-65 pubmed
    ..rickettsii or R. prowazekii. These latter results suggest that the 32-kDa C-terminal region of the molecule may serve as a membrane anchor domain...
  21. Alexeyev M, Winkler H. Membrane topology of the Rickettsia prowazekii ATP/ADP translocase revealed by novel dual pho-lac reporters. J Mol Biol. 1999;285:1503-13 pubmed publisher
    ..Our results were in agreement with the proposed in silico topological model in which Tlc traverses the cytoplasmic membrane of E. coli 12 times with its N and C termini facing the cytoplasm...
  22. Andersson J, Andersson S. Genome degradation is an ongoing process in Rickettsia. Mol Biol Evol. 1999;16:1178-91 pubmed publisher
    ..This may explain the low genomic G + C content (29%), the small genome size (1.1 Mb), and the high noncoding content (24%), as well as the presence of several pseudogenes in the Rickettsia prowazekii genome...
  23. Santhanagopalan V, Coker C, Radulovic S. Characterization of RP 333, a gene encoding CapD of Rickettsia prowazekii with UDP-glucose 4-epimerase activity. Gene. 2006;369:119-25 pubmed publisher
    ..prowazekii vaccine, generation of new antibiotics, and opening the way for research in membrane biogenesis with respect to the parasitic lifestyle of Rickettsia...
  24. Rahman M, Gillespie J, Kaur S, Sears K, Ceraul S, Beier Sexton M, et al. Rickettsia typhi possesses phospholipase A2 enzymes that are involved in infection of host cells. PLoS Pathog. 2013;9:e1003399 pubmed publisher
    ..Collectively, our study suggests that R. typhi utilizes two evolutionary divergent patatin phospholipases to support its intracellular life cycle, a mechanism distinguishing it from other rickettsial species...
  25. Tucker A, Winkler H, Driskell L, Wood D. S-adenosylmethionine transport in Rickettsia prowazekii. J Bacteriol. 2003;185:3031-5 pubmed
    ..The existence of a rickettsial transporter for AdoMet raises intriguing questions concerning the evolutionary relationship between the synthesis and transport of this essential metabolite...
  26. Ching W, Carl M, Dasch G. Mapping of monoclonal antibody binding sites on CNBr fragments of the S-layer protein antigens of Rickettsia typhi and Rickettsia prowazekii. Mol Immunol. 1992;29:95-105 pubmed
    ..Two types of antibodies bound to several CNBr fragments which contained both limited sequence similarity and modified amino acids either of which might account for the multisite binding of these antibodies...
  27. Shaw E, Marks G, Winkler H, Wood D. Transcriptional characterization of the Rickettsia prowazekii major macromolecular synthesis operon. J Bacteriol. 1997;179:6448-52 pubmed
    ..Quantitation of transcripts produced by the three ORFs determined the relative amounts of transcripts (ORF23 to dnaG to rpoD) to be 1:2.7:5.1...
  28. Wood D, Williamson L, Winkler H, Krause D. Nucleotide sequence of the Rickettsia prowazekii citrate synthase gene. J Bacteriol. 1987;169:3564-72 pubmed
    ..Codon usage in the rickettsial gltA gene was found to be very biased and differed from the pattern observed in E. coli. Adenine and uracil were used preferentially in the third base position of rickettsial codons...
  29. Rachek L, Tucker A, Winkler H, Wood D. Transformation of Rickettsia prowazekii to rifampin resistance. J Bacteriol. 1998;180:2118-24 pubmed
    ..This is the first successful demonstration of genetic transformation of Rickettsia prowazekii and represents the initial step in the establishment of a genetic system in this obligate intracellular pathogen...
  30. Emelyanov V, Demyanova N. Nucleotide sequence of the gene and features of the major outer membrane protein of a virulent Rickettsia prowazekii strain. Biochemistry (Mosc). 1999;64:494-503 pubmed
    ..Near the plp gene on the opposite strand, an origin of the gene that codes for the SecA subunit of a preprotein translocase was found...
  31. Syv nen A, Amiri H, Jamal A, Andersson S, Kurland C. A chimeric disposition of the elongation factor genes in Rickettsia prowazekii. J Bacteriol. 1996;178:6192-9 pubmed
    ..coli. This atypical disposition of genes suggests that intrachromosomal recombination between duplicated tuf genes has contributed to the evolution of the unique genomic architecture of R. prowazekii...
  32. Andersson S, Sharp P. Codon usage and base composition in Rickettsia prowazekii. J Mol Evol. 1996;42:525-36 pubmed
    ..5% and 21.4%, respectively. Extrapolation from these values suggests that R. prowazekii has around 800 genes and that 60-70% of the genome may be coding...
  33. Gaywee J, Xu W, Radulovic S, Bessman M, Azad A. The Rickettsia prowazekii invasion gene homolog (invA) encodes a Nudix hydrolase active on adenosine (5')-pentaphospho-(5')-adenosine. Mol Cell Proteomics. 2002;1:179-85 pubmed
    ..These data suggest that the rickettsial invasion protein likely plays a role in controlling the concentration of stress-induced dinucleoside oligophosphates following bacterial invasion...
  34. Moron C, Bouyer D, Yu X, Foil L, Crocquet Valdes P, Walker D. Phylogenetic analysis of the rompB genes of Rickettsia felis and Rickettsia prowazekii European-human and North American flying-squirrel strains. Am J Trop Med Hyg. 2000;62:598-603 pubmed
    ..Analysis of the R. felis rompB gene sequence showed 10-13% divergence from SFG rickettsiae and 18% divergence from the TG rickettsiae. The rompB of all sequenced strains of R. prowazekii showed an overall similarity of 99.7-99.9%...
  35. Abeykoon A, Chao C, Wang G, Gucek M, Yang D, Ching W. Two protein lysine methyltransferases methylate outer membrane protein B from Rickettsia. J Bacteriol. 2012;194:6410-8 pubmed publisher
  36. Sicheritz Pont n T, Kurland C, Andersson S. A phylogenetic analysis of the cytochrome b and cytochrome c oxidase I genes supports an origin of mitochondria from within the Rickettsiaceae. Biochim Biophys Acta. 1998;1365:545-51 pubmed
    ..We have estimated that the common ancestor of mitochondria and Rickettsiaceae dates back to more than 1500 million years ago...
  37. Andersson S, Zomorodipour A, Winkler H, Kurland C. Unusual organization of the rRNA genes in Rickettsia prowazekii. J Bacteriol. 1995;177:4171-5 pubmed
    ..In this organism, the 23S and the 5S rRNA genes are tightly linked to each other, whereas the 16S rRNA gene is separated from this cluster. The 23S-5S unit is preceded by the methionyl-tRNAfMet formyltransferase gene...
  38. Carl M, Dobson M, Ching W, Dasch G. Characterization of the gene encoding the protective paracrystalline-surface-layer protein of Rickettsia prowazekii: presence of a truncated identical homolog in Rickettsia typhi. Proc Natl Acad Sci U S A. 1990;87:8237-41 pubmed
    ..prowazekii SPA but had a 3674-base-pair region identical with the remainder of the R. prowazekii SPA gene sequence...
  39. Fournier P, Xeridat B, Raoult D. Isolation of a rickettsia related to Astrakhan fever rickettsia from a patient in Chad. Ann N Y Acad Sci. 2003;990:152-7 pubmed
    ..Although Astrakhan fever rickettsia is transmitted by Rhipicephalus ticks in Europe, further studies are indicated to identify its vector in Africa where these ticks are also prevalent...
  40. Frohlich K, Roberts R, Housley N, Audia J. Rickettsia prowazekii uses an sn-glycerol-3-phosphate dehydrogenase and a novel dihydroxyacetone phosphate transport system to supply triose phosphate for phospholipid biosynthesis. J Bacteriol. 2010;192:4281-8 pubmed publisher
    ..prowazekii transported and incorporated DHAP into phospholipids, thus implicating a role for GpsA in vivo as part of a novel rickettsial G3P acquisition pathway for phospholipid biosynthesis...
  41. Davis M, Ying Z, Brunner B, Pantoja A, Ferwerda F. Rickettsial relative associated with papaya bunchy top disease. Curr Microbiol. 1998;36:80-4 pubmed
    ..Although Rickettsia have been found naturally in arthropods and can be pathogenic to humans and other vertebrates, this is the first evidence of its kind implicating a Rickettsia as a plant pathogen...
  42. Ishikura M, Fujita H, Ando S, Matsuura K, Watanabe M. Phylogenetic analysis of spotted fever group Rickettsiae isolated from ticks in Japan. Microbiol Immunol. 2002;46:241-7 pubmed
    ..japonica, and 5 Ixodes isolates were associated with the R. helvetica. Based on previous genotypic and antigenic data, and the phylogenetic analysis presented here, strain AT-1 should be considered as a new species among SFG rickettsiae...
  43. Stenos J, Roux V, Walker D, Raoult D. Rickettsia honei sp. nov., the aetiological agent of Flinders Island spotted fever in Australia. Int J Syst Bacteriol. 1998;48 Pt 4:1399-404 pubmed publisher
    ..Indeed, it is proposed that TT-118 is a strain of R. honei which was previously isolated in Thailand. These results elucidate the presence of a unique SFG rickettsial species in Australasia...
  44. Shpynov S, Fournier P, Rudakov N, Tankibaev M, Tarasevich I, Raoult D. Detection of a rickettsia closely related to Rickettsia aeschlimannii, "Rickettsia heilongjiangensis," Rickettsia sp. strain RpA4, and Ehrlichia muris in ticks collected in Russia and Kazakhstan. J Clin Microbiol. 2004;42:2221-3 pubmed
    ..In Kazakhstan, we detected Rickettsia sp. strain RpA4 and a rickettsia closely related to Rickettsia aeschlimannii. These agents should be considered in a differential diagnosis of tick-borne infections in these areas...
  45. Saenz H, Engel P, Stoeckli M, Lanz C, Raddatz G, Vayssier Taussat M, et al. Genomic analysis of Bartonella identifies type IV secretion systems as host adaptability factors. Nat Genet. 2007;39:1469-76 pubmed publisher
    ..bacilliformis, and one has been lost by deletion. The 14 pathogenicity genes specific for the radiating lineage encode two laterally acquired type IV secretion systems, suggesting that these systems have a role in host adaptability...
  46. Loftis A, Reeves W, Szumlas D, Abbassy M, Helmy I, Moriarity J, et al. Surveillance of Egyptian fleas for agents of public health significance: Anaplasma, Bartonella, Coxiella, Ehrlichia, Rickettsia, and Yersinia pestis. Am J Trop Med Hyg. 2006;75:41-8 pubmed
    ..cheopis. Novel Bartonella genotypes were detected in X. cheopis and L. segnis from three cities. Coxiella burnetii was detected in two fleas. Anaplasma, Ehrlichia, and Y. pestis were not detected...
  47. Fournier P, Takada N, Fujita H, Raoult D. Rickettsia tamurae sp. nov., isolated from Amblyomma testudinarium ticks. Int J Syst Evol Microbiol. 2006;56:1673-5 pubmed publisher
    ..Such genotypic and phenotypic characteristics warrant its classification as a representative of a novel species, for which the name Rickettsia tamurae sp. nov. is proposed, with the type strain AT-1(T) (=CSUR R1(T))...
  48. Reeves W, Nelder M, Korecki J. Bartonella and Rickettsia in fleas and lice from mammals in South Carolina, U.S.A. J Vector Ecol. 2005;30:310-5 pubmed
    ..Cat fleas harbored one of two novel genotypes of Rickettsia. A third novel Rickettsia was detected in Orchopeas howardi from an eastern gray squirrel...
  49. Anderson B, Tzianabos T. Comparative sequence analysis of a genus-common rickettsial antigen gene. J Bacteriol. 1989;171:5199-201 pubmed
  50. Renesto P, Samson L, Ogata H, Azza S, Fourquet P, Gorvel J, et al. Identification of two putative rickettsial adhesins by proteomic analysis. Res Microbiol. 2006;157:605-12 pubmed publisher
    ..Both proteins are highly conserved within the Rickettsia genus and might play a critical role in their pathogenicity. These data may have important implications for the development of future vaccines against rickettsial infections...
  51. Furuya Y, Katayama T, Yoshida Y, Kaiho I. Specific amplification of Rickettsia japonica DNA from clinical specimens by PCR. J Clin Microbiol. 1995;33:487-9 pubmed
    ..japonica and also the DNA from blood clots of patients with spotted fever group rickettsiosis. The results indicated that this method is suitable for the diagnosis of spotted fever group rickettsiosis in Japan...
  52. Beninati T, Genchi C, Torina A, Caracappa S, Bandi C, Lo N. Rickettsiae in ixodid ticks, Sicily. Emerg Infect Dis. 2005;11:509-11 pubmed publisher
  53. La Scola B, Meconi S, Fenollar F, Rolain J, Roux V, Raoult D. Emended description of Rickettsia felis (Bouyer et al. 2001), a temperature-dependent cultured bacterium. Int J Syst Evol Microbiol. 2002;52:2035-41 pubmed publisher
    ..felis and those observed for the isolate in this study indicated some differences, although concurrent analysis of the two was not possible as no extant isolates of the first isolate of R. felis exist...
  54. Drancourt M, Raoult D. Characterization of mutations in the rpoB gene in naturally rifampin-resistant Rickettsia species. Antimicrob Agents Chemother. 1999;43:2400-3 pubmed
    ..rpoB-based phylogenetic relationships among these rickettsial species yielded topologies which were in accordance with previously published phylogenies...
  55. Radulovic S, Troyer J, Beier M, Lau A, Azad A. Identification and molecular analysis of the gene encoding Rickettsia typhi hemolysin. Infect Immun. 1999;67:6104-8 pubmed
    ..mirabilis. The availability of the cloned R. typhi tlyC will permit further characterization and definition of its role in rickettsial virulence...
  56. Simser J, Palmer A, Munderloh U, Kurtti T. Isolation of a spotted fever group Rickettsia, Rickettsia peacockii, in a Rocky Mountain wood tick, Dermacentor andersoni, cell line. Appl Environ Microbiol. 2001;67:546-52 pubmed publisher
    ..Establishing cell lines from embryonic tissues of ticks offers an alternative technique for isolation of rickettsiae that are transovarially transmitted...
  57. Bouyer D, Stenos J, Crocquet Valdes P, Moron C, Popov V, Zavala Velazquez J, et al. Rickettsia felis: molecular characterization of a new member of the spotted fever group. Int J Syst Evol Microbiol. 2001;51:339-47 pubmed publisher
    ..felis as a member of the SFG. The organism is passed trans-stadially and transovarially, and infection in the cat flea has been observed in the midgut, tracheal matrix, muscle, hypodermis, ovaries and testes...
  58. Billings A, Yu X, Teel P, Walker D. Detection of a spotted fever group rickettsia in Amblyomma cajennense (Acari: Ixodidae) in south Texas. J Med Entomol. 1998;35:474-8 pubmed
    ..cajennense ticks in Texas and the United States. If this rickettsia is pathogenic, exposure to infected A. cajennense ticks may pose a previously unrecognized health risk to people who have been fed upon by these ticks...
  59. Fournier P, Fujita H, Takada N, Raoult D. Genetic identification of rickettsiae isolated from ticks in Japan. J Clin Microbiol. 2002;40:2176-81 pubmed
    ..Finally, we identified a new genotype of unknown pathogenicity, genotype AT, that was isolated from Amblyomma testudinarium ticks and that is closely related to a Slovakian genotype obtained from Ixodes ricinus ticks...
  60. Parola P, Cornet J, Sanogo Y, Miller R, Thien H, Gonzalez J, et al. Detection of Ehrlichia spp., Anaplasma spp., Rickettsia spp., and other eubacteria in ticks from the Thai-Myanmar border and Vietnam. J Clin Microbiol. 2003;41:1600-8 pubmed
    ..Finally, two bacteria named Eubacterium sp. strain Hw124 and Eubacterium sp. strain Hw191 were identified in Haemaphysalis wellingtoni ticks collected from chicken in Thailand; these strains could belong to a new group of bacteria...
  61. Hirunkanokpun S, Kittayapong P, Cornet J, Gonzalez J. Molecular evidence for novel tick-associated spotted fever group rickettsiae from Thailand. J Med Entomol. 2003;40:230-7 pubmed
    ..Results indicated that the three Thai rickettsiae detected in this study represent new rickettsial genotypes and form a separate cluster among the spotted fever group rickettsiae...
  62. Renesto P, Dehoux P, Gouin E, Touqui L, Cossart P, Raoult D. Identification and characterization of a phospholipase D-superfamily gene in rickettsiae. J Infect Dis. 2003;188:1276-83 pubmed publisher
    ..This enzyme might account for the activity previously attributed to PLA(2) and might be critical for the intracellular life of these bacteria...
  63. Labruna M, Whitworth T, Horta M, Bouyer D, McBride J, Pinter A, et al. Rickettsia species infecting Amblyomma cooperi ticks from an area in the state of São Paulo, Brazil, where Brazilian spotted fever is endemic. J Clin Microbiol. 2004;42:90-8 pubmed
    ..These results do not support the role of A. cooperi in the ecology of R. rickettsii in the area studied, but they add two more species of rickettsiae to the poorly developed list of species occurring in ticks in South America...
  64. Mediannikov O, Sidelnikov Y, Ivanov L, Mokretsova E, Fournier P, Tarasevich I, et al. Acute tick-borne rickettsiosis caused by Rickettsia heilongjiangensis in Russian Far East. Emerg Infect Dis. 2004;10:810-7 pubmed publisher
    ..heilongjiangensis. Clinical and epidemiologic data on these patients show that this disease is similar to other tick-borne rickettsioses...
  65. Baldridge G, Burkhardt N, Simser J, Kurtti T, Munderloh U. Sequence and expression analysis of the ompA gene of Rickettsia peacockii, an endosymbiont of the Rocky Mountain wood tick, Dermacentor andersoni. Appl Environ Microbiol. 2004;70:6628-36 pubmed publisher
    ..peacockii. Double immunolabeling studies revealed actin tail structures in tick cells infected with R. rickettsii strain Hlp#2 but not in cells infected with R. peacockii...
  66. Gottlieb Y, Ghanim M, Chiel E, Gerling D, Portnoy V, Steinberg S, et al. Identification and localization of a Rickettsia sp. in Bemisia tabaci (Homoptera: Aleyrodidae). Appl Environ Microbiol. 2006;72:3646-52 pubmed publisher
  67. Labruna M, Whitworth T, Bouyer D, McBride J, Camargo L, Camargo E, et al. Rickettsia bellii and Rickettsia amblyommii in Amblyomma ticks from the State of Rondônia, Western Amazon, Brazil. J Med Entomol. 2004;41:1073-81 pubmed
    ..amblyommii infection of Vero cells was analyzed by transmission electron microscopy. This study adds South America to the known geographic distribution of R. amblyommii and reports rickettsiae in six Amblyomma species for the first time...
  68. Werren J, Hurst G, Zhang W, Breeuwer J, Stouthamer R, Majerus M. Rickettsial relative associated with male killing in the ladybird beetle (Adalia bipunctata). J Bacteriol. 1994;176:388-94 pubmed
    ..Discovery of a close relative of rickettsias associated with sex ratio distortion in insects has implications for the evolution and population dynamics of this bacterial genus...
  69. Radulovic S, Rahman M, Beier M, Azad A. Molecular and functional analysis of the Rickettsia typhi groESL operon. Gene. 2002;298:41-8 pubmed
    ..Complementation assay by R. typhi groESL in a temperature sensitive Escherichia coli groEL mutant restored significant growth ability at non-permissive temperature...
  70. Shpynov S, Fournier P, Rudakov N, Samoilenko I, Reshetnikova T, Yastrebov V, et al. Molecular identification of a collection of spotted Fever group rickettsiae obtained from patients and ticks from Russia. Am J Trop Med Hyg. 2006;74:440-3 pubmed
    ..Clinicians should be aware that several spotted fever rickettsioses with different prognoses coexist in Russia in areas where NATT was the only previously recognized rickettsiosis...
  71. Ishikura M, Ando S, Shinagawa Y, Matsuura K, Hasegawa S, Nakayama T, et al. Phylogenetic analysis of spotted fever group rickettsiae based on gltA, 17-kDa, and rOmpA genes amplified by nested PCR from ticks in Japan. Microbiol Immunol. 2003;47:823-32 pubmed
    ..ovatus and I. persulcatus were identical with R. helvetica. Genotype IX detected from I. nipponensis was genetically close to the strains IRS3, IRS4, and IrR/Munich isolated from I. ricinus in Slovakia and German...
  72. von Der Schulenburg J, Habig M, Sloggett J, Webberley K, Bertrand D, Hurst G, et al. Incidence of male-killing Rickettsia spp. (alpha-proteobacteria) in the ten-spot ladybird beetle Adalia decempunctata L. (Coleoptera: Coccinellidae). Appl Environ Microbiol. 2001;67:270-7 pubmed publisher
    ..We discuss the importance of these findings to our understanding of the evolution and dynamics of symbiotic associations between male-killing bacteria and their insect hosts...