Experts and Doctors on metalloproteases in Salt Lake City, Utah, United States

Summary

Locale: Salt Lake City, Utah, United States
Topic: metalloproteases

Top Publications

  1. Davis M, Birnie A, Chan A, Page A, Jorgensen E. A conserved metalloprotease mediates ecdysis in Caenorhabditis elegans. Development. 2004;131:6001-8 pubmed
    ..NAS-37 degradation of the Haemonchus cuticle suggests that the metalloproteases and the cuticle substrates involved in exsheathment of parasitic nematodes are conserved in free-living nematodes. ..
  2. Bestwick M, Khalimonchuk O, Pierrel F, Winge D. The role of Coa2 in hemylation of yeast Cox1 revealed by its genetic interaction with Cox10. Mol Cell Biol. 2010;30:172-85 pubmed publisher
    ..We postulate that the mutant Cox10 complex has enhanced efficiency in the addition of heme a to Cox1. Coa2 appears to impart stability to the oligomeric wild-type Cox10 complex involved in Cox1 hemylation. ..
  3. Khalimonchuk O, Jeong M, Watts T, Ferris E, Winge D. Selective Oma1 protease-mediated proteolysis of Cox1 subunit of cytochrome oxidase in assembly mutants. J Biol Chem. 2012;287:7289-300 pubmed publisher
    ..Specific Cox1 proteolysis in coa2? cells arises from a combination of Oma1 activation and a susceptible conformation of Cox1. ..

Detail Information

Publications3

  1. Davis M, Birnie A, Chan A, Page A, Jorgensen E. A conserved metalloprotease mediates ecdysis in Caenorhabditis elegans. Development. 2004;131:6001-8 pubmed
    ..NAS-37 degradation of the Haemonchus cuticle suggests that the metalloproteases and the cuticle substrates involved in exsheathment of parasitic nematodes are conserved in free-living nematodes. ..
  2. Bestwick M, Khalimonchuk O, Pierrel F, Winge D. The role of Coa2 in hemylation of yeast Cox1 revealed by its genetic interaction with Cox10. Mol Cell Biol. 2010;30:172-85 pubmed publisher
    ..We postulate that the mutant Cox10 complex has enhanced efficiency in the addition of heme a to Cox1. Coa2 appears to impart stability to the oligomeric wild-type Cox10 complex involved in Cox1 hemylation. ..
  3. Khalimonchuk O, Jeong M, Watts T, Ferris E, Winge D. Selective Oma1 protease-mediated proteolysis of Cox1 subunit of cytochrome oxidase in assembly mutants. J Biol Chem. 2012;287:7289-300 pubmed publisher
    ..Specific Cox1 proteolysis in coa2? cells arises from a combination of Oma1 activation and a susceptible conformation of Cox1. ..