Experts and Doctors on molecular sequence data in Dallas, Texas, United States


Locale: Dallas, Texas, United States
Topic: molecular sequence data

Top Publications

  1. Jarosik G, Hansen E. Cloning and sequencing of the Haemophilus influenzae exbB and exbD genes. Gene. 1995;152:89-92 pubmed
    ..Plasmid-encoded Hi exbB and exbD partially complemented an E. coli exbB/exbD mutation. ..
  2. Ullrich B, Li C, Zhang J, McMahon H, Anderson R, Geppert M, et al. Functional properties of multiple synaptotagmins in brain. Neuron. 1994;13:1281-91 pubmed
  3. Yang Q, Bassel Duby R, Williams R. Transient expression of a winged-helix protein, MNF-beta, during myogenesis. Mol Cell Biol. 1997;17:5236-43 pubmed
  4. May E, Lambert C, Holtmeier W, Hennemann A, Zeitz M, Duchmann R. Regional variation of the alphabeta T cell repertoire in the colon of healthy individuals and patients with Crohn's disease. Hum Immunol. 2002;63:467-80 pubmed
    ..This does not exclude a pathogenic role of expanded T cells in CD through more subtle changes, but emphasizes the need to distinguish them from a discontinuous distribution of clonally expanded T cells in normal colon. ..
  5. Lau K, Herring W, Chuang J, McKean M, Danner D, Cox R, et al. Structure of the gene encoding dihydrolipoyl transacylase (E2) component of human branched chain alpha-keto acid dehydrogenase complex and characterization of an E2 pseudogene. J Biol Chem. 1992;267:24090-6 pubmed
    ..However, the E2 pseudogene contains multiple base changes, deletions, and insertions, and is flanked by short direct repeats. The data indicate that the E2 pseudogene is a retroposon. ..
  6. Pascual V, Randen I, Thompson K, Sioud M, Forre O, Natvig J, et al. The complete nucleotide sequences of the heavy chain variable regions of six monospecific rheumatoid factors derived from Epstein-Barr virus-transformed B cells isolated from the synovial tissue of patients with rheumatoid arthritis. Further evidence. J Clin Invest. 1990;86:1320-8 pubmed
    ..This RF displays a nearly germline configuration throughout its entire heavy chain and represents another example of an autoantibody encoded by one of the VH gene segments from the preimmune fetal repertoire. ..
  7. Orr E, Bewley G, Orr W. cDNA and deduced amino acid sequence of Drosophila catalase. Nucleic Acids Res. 1990;18:3663 pubmed
  8. Guzman Verduzco L, Kupersztoch Y. Rectification of two Escherichia coli heat-stable enterotoxin allele sequences and lack of biological effect of changing the carboxy-terminal tyrosine to histidine. Infect Immun. 1989;57:645-8 pubmed
  9. Fee B, Dempsey W. Nucleotide sequence of gene X of antibiotic resistance plasmid R100. Nucleic Acids Res. 1988;16:4726 pubmed

More Information

Publications173 found, 100 shown here

  1. Henke R, Butow R, Perlman P. Maturase and endonuclease functions depend on separate conserved domains of the bifunctional protein encoded by the group I intron aI4 alpha of yeast mitochondrial DNA. EMBO J. 1995;14:5094-9 pubmed
    ..This study indicates that the two functions depend on separate domains of the intron-encoded protein. ..
  2. Herrscher R, Kaplan M, Lelsz D, Das C, Scheuermann R, Tucker P. The immunoglobulin heavy-chain matrix-associating regions are bound by Bright: a B cell-specific trans-activator that describes a new DNA-binding protein family. Genes Dev. 1995;9:3067-82 pubmed
    ..To bind DNA, Bright requires a novel tetramerization domain and a previously undescribed domain that shares identity with several proteins, including SWI1, a component of the SWI/SNF complex. ..
  3. Hosaka M, Sudhof T. Synapsins I and II are ATP-binding proteins with differential Ca2+ regulation. J Biol Chem. 1998;273:1425-9 pubmed
    ..Our studies suggest that synapsins I and II function on synaptic vesicles as ATP-binding proteins that are differentially regulated by Ca2+. ..
  4. Lu J, Webb R, Richardson J, Olson E. MyoR: a muscle-restricted basic helix-loop-helix transcription factor that antagonizes the actions of MyoD. Proc Natl Acad Sci U S A. 1999;96:552-7 pubmed
    ..These results suggest a role for MyoR as a lineage-restricted transcriptional repressor of the muscle differentiation program. ..
  5. Zwirner N, Dole K, Stastny P. Differential surface expression of MICA by endothelial cells, fibroblasts, keratinocytes, and monocytes. Hum Immunol. 1999;60:323-30 pubmed
    ..Moreover, the expression of MICA on the surface of endothelial cells makes this polymorphic molecule a possible target during the immune response of graft rejection in organ transplantation. ..
  6. Janz R, Sudhof T. SV2C is a synaptic vesicle protein with an unusually restricted localization: anatomy of a synaptic vesicle protein family. Neuroscience. 1999;94:1279-90 pubmed
  7. Xu Be -, Stippec S, Robinson F, Cobb M. Hydrophobic as well as charged residues in both MEK1 and ERK2 are important for their proper docking. J Biol Chem. 2001;276:26509-15 pubmed
    ..These findings suggest complex interactions of MEK1 D domains with ERK2 that influence its activation and its effects on substrates. ..
  8. Kawaguchi T, Osatomi K, Yamashita H, Kabashima T, Uyeda K. Mechanism for fatty acid "sparing" effect on glucose-induced transcription: regulation of carbohydrate-responsive element-binding protein by AMP-activated protein kinase. J Biol Chem. 2002;277:3829-35 pubmed
    ..AMPK was activated by the increased AMP that was generated by the fatty acid activation. ..
  9. Prajapati S, Gaynor R. Regulation of Ikappa B kinase (IKK)gamma /NEMO function by IKKbeta -mediated phosphorylation. J Biol Chem. 2002;277:24331-9 pubmed
    ..These results indicate that the differential phosphorylation of IKKgamma/NEMO by IKKbeta and perhaps other kinases may be important in regulating IKK activity. ..
  10. Dai H, Shin O, Machius M, Tomchick D, Sudhof T, Rizo J. Structural basis for the evolutionary inactivation of Ca2+ binding to synaptotagmin 4. Nat Struct Mol Biol. 2004;11:844-9 pubmed
  11. Arai S, Miyazaki T. Impaired maturation of myeloid progenitors in mice lacking novel Polycomb group protein MBT-1. EMBO J. 2005;24:1863-73 pubmed
    ..We also show that MBT-1 appears to influence myelopoiesis by transiently enhancing p57(KIP2) expression levels. ..
  12. Meeson A, Shi X, Alexander M, Williams R, Allen R, Jiang N, et al. Sox15 and Fhl3 transcriptionally coactivate Foxk1 and regulate myogenic progenitor cells. EMBO J. 2007;26:1902-12 pubmed
    ..These studies demonstrate that Sox15, Fhl3 and Foxk1 function to coordinately regulate the myogenic progenitor cell population and skeletal muscle regeneration. ..
  13. Tsakiri K, Cronkhite J, Kuan P, Xing C, Raghu G, Weissler J, et al. Adult-onset pulmonary fibrosis caused by mutations in telomerase. Proc Natl Acad Sci U S A. 2007;104:7552-7 pubmed
    ..Thus, mutations in TERT or TERC that result in telomere shortening over time confer a dramatic increase in susceptibility to adult-onset IPF. ..
  14. Wynn R, Li J, Brautigam C, Chuang J, Chuang D. Structural and biochemical characterization of human mitochondrial branched-chain ?-ketoacid dehydrogenase phosphatase. J Biol Chem. 2012;287:9178-92 pubmed publisher
    ..Alteration of the nearby Arg-104 increases the K(m) for p-E1b peptide by 60-fold, suggesting that this residue is critical for the recognition of the native p-E1b protein. ..
  15. Salomon D, Guo Y, Kinch L, Grishin N, Gardner K, Orth K. Effectors of animal and plant pathogens use a common domain to bind host phosphoinositides. Nat Commun. 2013;4:2973 pubmed publisher
    ..Thus, our findings suggest a possible mechanism for promoting refolding of Type III effectors after delivery into host cells. ..
  16. Karamyshev A, Patrick A, Karamysheva Z, Griesemer D, Hudson H, Tjon Kon Sang S, et al. Inefficient SRP interaction with a nascent chain triggers a mRNA quality control pathway. Cell. 2014;156:146-57 pubmed publisher
    ..The results reveal a previously unappreciated general mechanism of translational quality control, in which specific mRNA degradation preemptively regulates aberrant protein production (RAPP). ..
  17. Funk W, Wright W. Cyclic amplification and selection of targets for multicomponent complexes: myogenin interacts with factors recognizing binding sites for basic helix-loop-helix, nuclear factor 1, myocyte-specific enhancer-binding factor 2, and COMP1 factor. Proc Natl Acad Sci U S A. 1992;89:9484-8 pubmed
  18. Chen W, Andres D, Goldstein J, Russell D, Brown M. cDNA cloning and expression of the peptide-binding beta subunit of rat p21ras farnesyltransferase, the counterpart of yeast DPR1/RAM1. Cell. 1991;66:327-34 pubmed
    ..The rat beta subunit shows 37% sequence identity with the protein encoded by the yeast DPR1/RAM1 gene, indicating that DPR1/RAM1 is the yeast counterpart of the peptide-binding subunit of the mammalian farnesyltransferase. ..
  19. Craft C, Lolley R, Seldin M, Lee R. Rat pineal gland phosducin: cDNA isolation, nucleotide sequence, and chromosomal assignment in the mouse. Genomics. 1991;10:400-9 pubmed
    ..In keeping with a proposed role of retinal phosducin in down-regulation of the photo-transduction cascade, a modulatory role in signal transduction is proposed for pineal phosducin. ..
  20. Hofmann S, Goldstein J, Orth K, Moomaw C, Slaughter C, Brown M. Molecular cloning of a histidine-rich Ca2+-binding protein of sarcoplasmic reticulum that contains highly conserved repeated elements. J Biol Chem. 1989;264:18083-90 pubmed
    ..We suggest that the histidine-rich Ca2+-binding protein described in the current study be designated HCP. The role of HCP in Ca2+ homeostasis in the sarcoplasmic reticulum of skeletal and cardiac muscle remains to be determined. ..
  21. Brose N, Hofmann K, Hata Y, Sudhof T. Mammalian homologues of Caenorhabditis elegans unc-13 gene define novel family of C2-domain proteins. J Biol Chem. 1995;270:25273-80 pubmed
    ..The presence of C1- and C2-domains in these proteins and the phenotype of the C. elegans mutants raise the possibility that Munc13s may have an essential signaling role during neurotransmitter release. ..
  22. Davie J, Wynn R, Meng M, Huang Y, Aalund G, Chuang D, et al. Expression and characterization of branched-chain alpha-ketoacid dehydrogenase kinase from the rat. Is it a histidine-protein kinase?. J Biol Chem. 1995;270:19861-7 pubmed
    ..Significant corrections to the published cDNA sequence of rat branched-chain alpha-ketoacid dehydrogenase kinase are included...
  23. DeLuca A, Rush J, Lehrman M, Waechter C. Mannolipid donor specificity of glycosylphosphatidylinositol mannosyltransferase-I (GPIMT-I) determined with an assay system utilizing mutant CHO-K1 cells. Glycobiology. 1994;4:909-15 pubmed
    ..abstract truncated at 250 words) ..
  24. Noble L, Simpson E, Johns A, Bulun S. Aromatase expression in endometriosis. J Clin Endocrinol Metab. 1996;81:174-9 pubmed
    ..Increased IL-6 and IL-11 expression in these tissues suggests that P450arom expression in endometriosis may be regulated in part by these cytokines. ..
  25. Del Mastro R, Wang L, Simmons A, Gallardo T, Clines G, Ashley J, et al. Human chromosome-specific cDNA libraries: new tools for gene identification and genome annotation. Genome Res. 1995;5:185-94 pubmed
    ..This study more than doubles the number of genes mapped to chromosome 5 and describes an important new tool for disease gene isolation. ..
  26. Bassett M, McCarthy J, Waterman M, Sliter T. Sequence and developmental expression of Cyp18, a member of a new cytochrome P450 family from Drosophila. Mol Cell Endocrinol. 1997;131:39-49 pubmed
    ..High Cyp18 expression was observed in body wall and gut while negligible expression was observed in salivary glands and fat body. ..
  27. Lu J, Richardson J, Olson E. Capsulin: a novel bHLH transcription factor expressed in epicardial progenitors and mesenchyme of visceral organs. Mech Dev. 1998;73:23-32 pubmed
  28. Bashour A, Bloom G. 58K, a microtubule-binding Golgi protein, is a formiminotransferase cyclodeaminase. J Biol Chem. 1998;273:19612-7 pubmed
    ..The physiological significance of the microtubule binding activity of FTCD is thus called into question, but an association of FTCD with the Golgi apparatus has now been established. ..
  29. Mayo M, Jenkins R, Combes B, Lipsky P. Association of clonally expanded T cells with the syndrome of primary biliary cirrhosis and limited scleroderma. Hepatology. 1999;29:1635-42 pubmed
    ..These clonal expansions provide evidence that stimulation of clonal populations of CD8(+) T cells is associated with the clinical syndrome of PBC with CREST. ..
  30. Patterson C, Schaub T, Coleman E, Davis E. Developmental regulation of FKBP65. An ER-localized extracellular matrix binding-protein. Mol Biol Cell. 2000;11:3925-35 pubmed
    ..Taken together, these results support an ER-localized FKBP65-tropoelastin interaction that occurs specifically during growth and development of tissues. ..
  31. Kong Y, Shelton J, Rothermel B, Li X, Richardson J, Bassel Duby R, et al. Cardiac-specific LIM protein FHL2 modifies the hypertrophic response to beta-adrenergic stimulation. Circulation. 2001;103:2731-8 pubmed
    ..01). FHL2 is an early marker of cardiogenic cells and a cardiac-specific LIM protein in the adult. FHL2 is not required for normal cardiac development but modifies the hypertrophic response to beta-adrenergic stimulation. ..
  32. Rombel I, Sykes K, Rayner S, Johnston S. ORF-FINDER: a vector for high-throughput gene identification. Gene. 2002;282:33-41 pubmed
    ..We envision that ORF-FINDER will have several applications including genome sequencing projects, gene building from oligonucleotides and construction of expression libraries enriched for ORFs. ..
  33. Chen X, Tomchick D, Kovrigin E, Arac D, Machius M, Sudhof T, et al. Three-dimensional structure of the complexin/SNARE complex. Neuron. 2002;33:397-409 pubmed
    ..These results suggest that complexin stabilizes the fully assembled SNARE complex as a key step that enables the exquisitely high speed of Ca(2+)-evoked neurotransmitter release. ..
  34. Lee A, Zareei M, Daefler S. Identification of a NIPSNAP homologue as host cell target for Salmonella virulence protein SpiC. Cell Microbiol. 2002;4:739-50 pubmed
    ..We hypothesize that TassC is a host cell factor that determines vesicular trafficking in macrophages and is inactivated by Salmonella SpiC...
  35. Cheng J, Motola D, Mangelsdorf D, Russell D. De-orphanization of cytochrome P450 2R1: a microsomal vitamin D 25-hydroxilase. J Biol Chem. 2003;278:38084-93 pubmed
    ..CYP2R1 mRNA is abundant in the liver and testis, and present at lower levels in other tissues. The data suggest that CYP2R1 is a strong candidate for the microsomal vitamin D 25-hydroxylase. ..
  36. Zhang L, Ding J, Yang B, He G, Roe C. Characterization of the bidirectional promoter region between the human genes encoding VLCAD and PSD-95. Genomics. 2003;82:660-8 pubmed
    ..Site-directed mutagenesis experiments showed that a mutated activator protein 2-binding site markedly reduced the transcriptional activity of both promoters and abolished the minimal VLCAD promoter's response to DEHP treatment. ..
  37. Sevrioukov E, Moghrabi N, Kuhn M, KRAMER H. A mutation in dVps28 reveals a link between a subunit of the endosomal sorting complex required for transport-I complex and the actin cytoskeleton in Drosophila. Mol Biol Cell. 2005;16:2301-12 pubmed
  38. Krishna S, Sadreyev R, Grishin N. A tale of two ferredoxins: sequence similarity and structural differences. BMC Struct Biol. 2006;6:8 pubmed
    ..Functionally meaningful sequence similarity may sometimes be reflected only in local structural similarity, but not in global fold similarity. If detected and used naively, such similarities may lead to incorrect fold predictions. ..
  39. Waldrop S, Chan C, Cagatay T, Zhang S, Rousset R, Mack J, et al. An unconventional nuclear localization motif is crucial for function of the Drosophila Wnt/wingless antagonist Naked cuticle. Genetics. 2006;174:331-48 pubmed
    ..Our studies suggest that Nkd targets Dsh-dependent signal transduction steps in both cytoplasmic and nuclear compartments of cells receiving the Wnt signal. ..
  40. Huang N, Sorci L, Zhang X, Brautigam C, Li X, Raffaelli N, et al. Bifunctional NMN adenylyltransferase/ADP-ribose pyrophosphatase: structure and function in bacterial NAD metabolism. Structure. 2008;16:196-209 pubmed publisher
    ..The latter observation provided new insights into the ligand binding mode of ADPR-gated Ca2+ channel TRPM2. ..
  41. Deng J, Lang S, Wylie C, Hammes S. The Xenopus laevis isoform of G protein-coupled receptor 3 (GPR3) is a constitutively active cell surface receptor that participates in maintaining meiotic arrest in X. laevis oocytes. Mol Endocrinol. 2008;22:1853-65 pubmed publisher
  42. Partch C, Card P, Amezcua C, Gardner K. Molecular basis of coiled coil coactivator recruitment by the aryl hydrocarbon receptor nuclear translocator (ARNT). J Biol Chem. 2009;284:15184-92 pubmed publisher
    ..Identification of this ARNT-coactivator interface illustrates how ARNT PAS-B is used to form critical interactions with both bHLH-PAS partners and coactivators that are required for transcriptional responses. ..
  43. Quagliarini F, Wang Y, Kozlitina J, Grishin N, Hyde R, Boerwinkle E, et al. Atypical angiopoietin-like protein that regulates ANGPTL3. Proc Natl Acad Sci U S A. 2012;109:19751-6 pubmed publisher
    ..Inhibition of ANGPTL8 provides a new therapeutic strategy for reducing plasma lipoprotein levels. ..
  44. Shoji Kawata S, Sumpter R, Leveno M, Campbell G, Zou Z, Kinch L, et al. Identification of a candidate therapeutic autophagy-inducing peptide. Nature. 2013;494:201-6 pubmed publisher
    ..Thus, through the characterization of a domain of beclin 1 that interacts with HIV-1 Nef, we have developed an autophagy-inducing peptide that has potential efficacy in the treatment of human diseases...
  45. Wong K, Sharma A, Awasthi S, Matlock E, Rogers L, Van Lint C, et al. HIV-1 Tat interactions with p300 and PCAF transcriptional coactivators inhibit histone acetylation and neurotrophin signaling through CREB. J Biol Chem. 2005;280:9390-9 pubmed
    ..Importantly, these findings suggest that HIV-1 Tat-coactivator interactions may contribute to neurotrophin signaling impairments and neuronal apoptosis associated with HIV-1 infections of the CNS. ..
  46. Imai T, Globerman H, Gertner J, Kagawa N, Waterman M. Expression and purification of functional human 17 alpha-hydroxylase/17,20-lyase (P450c17) in Escherichia coli. Use of this system for study of a novel form of combined 17 alpha-hydroxylase/17,20-lyase deficiency. J Biol Chem. 1993;268:19681-9 pubmed
    ..Upon expression of these mutant proteins in E. coli, the Tyr64 mutant has 15% of the wild type 17 alpha-hydroxylase activity, whereas the Ile112 duplication shows no activity, results consistent with the observed clinical phenotype. ..
  47. Shin E, Perryman L, Meek K. A kinase-negative mutation of DNA-PK(CS) in equine SCID results in defective coding and signal joint formation. J Immunol. 1997;158:3565-9 pubmed
  48. Rothrock C, House A, Lynch K. HnRNP L represses exon splicing via a regulated exonic splicing silencer. EMBO J. 2005;24:2792-802 pubmed
    ..Together, these studies demonstrate that hnRNP-L is the primary protein through which CD45 exon 4 silencing is mediated by the regulatory sequence ESS1. ..
  49. Castrillon D, Wasserman S. Diaphanous is required for cytokinesis in Drosophila and shares domains of similarity with the products of the limb deformity gene. Development. 1994;120:3367-77 pubmed
    ..These formin homology domains, which we have termed FH1 and FH2, are also found in Bni1p, the product of a Saccharomyces cerevisiae gene required for normal cytokinesis in diploid yeast cells. ..
  50. Yan Z, Serrano A, Schiaffino S, Bassel Duby R, Williams R. Regulatory elements governing transcription in specialized myofiber subtypes. J Biol Chem. 2001;276:17361-6 pubmed
    ..In addition, we demonstrated a previously unsuspected role for an intragenic E-box motif as a negative regulatory element contributing to the tightly regulated variation in myoglobin gene expression among particular myofiber subtypes. ..
  51. Jia J, Amanai K, Wang G, Tang J, Wang B, Jiang J. Shaggy/GSK3 antagonizes Hedgehog signalling by regulating Cubitus interruptus. Nature. 2002;416:548-52 pubmed
    ..We propose that Sgg/GSK3 acts in conjunction with PKA to cause hyperphosphorylation of Ci, which targets it for proteolytic processing, and that Hh opposes Ci proteolysis by promoting its dephosphorylation. ..
  52. Steger K, Avery L. The GAR-3 muscarinic receptor cooperates with calcium signals to regulate muscle contraction in the Caenorhabditis elegans pharynx. Genetics. 2004;167:633-43 pubmed
    ..Because the effects of GAR-3 signaling on membrane depolarization and muscle contraction can be separated, we conclude that GAR-3 regulates multiple calcium-dependent processes in the C. elegans pharyngeal muscle. ..
  53. Maiti M, Lee H, Liu Y. QIP, a putative exonuclease, interacts with the Neurospora Argonaute protein and facilitates conversion of duplex siRNA into single strands. Genes Dev. 2007;21:590-600 pubmed publisher
    ..Together, these results suggest that both the cleavage and removal of the passenger strand from the siRNA duplex are important steps in RNAi pathways...
  54. Brown N, Esser V, Gonzalez A, Evans C, Slaughter C, Foster D, et al. Mitochondrial import and processing of rat liver carnitine palmitoyltransferase II defines the amino terminus of the mature protein. Possibility of differential modification of the rat and human isoforms. J Biol Chem. 1991;266:15446-9 pubmed
    ..Finally, the recent suggestion by Brady et al. (Brady, P. S., Liu, J. S., Park, E. A., Hanson, R. W., and Brady, L. J. (1991) FASEB J. 5, A817) that our CPT II cDNA construct is incomplete in the 5'-coding region is refuted. ..
  55. Matsumine H, Herbst M, Ou S, Wilson J, McPhaul M. Aromatase mRNA in the extragonadal tissues of chickens with the henny-feathering trait is derived from a distinctive promoter structure that contains a segment of a retroviral long terminal repeat. Functional organization of the Sebright, Leghorn, an. J Biol Chem. 1991;266:19900-7 pubmed
    ..Nucleotide sequence analysis of this 5' terminus indicates that this segment is derived from a retroviral long terminal repeat. ..
  56. Kim M, Chelliah Y, Kim S, Otwinowski Z, Bezprozvanny I. Secondary structure of Huntingtin amino-terminal region. Structure. 2009;17:1205-12 pubmed publisher
    ..We further propose that the pathogenic polyQ expansion in the Htt protein increases the length of the random coil, which promotes aggregation and facilitates abnormal interactions with other proteins in cells. ..
  57. Hua X, Yokoyama C, Wu J, Briggs M, Brown M, Goldstein J, et al. SREBP-2, a second basic-helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory element. Proc Natl Acad Sci U S A. 1993;90:11603-7 pubmed
    ..At high levels transcription reached a maximum, and the effects were no longer additive. The reason for the existence of two SREBPs and the mechanism by which they are regulated by sterols remain to be determined. ..
  58. Kang J, Chen Y, Zhao Y, Yu H. Autophosphorylation-dependent activation of human Mps1 is required for the spindle checkpoint. Proc Natl Acad Sci U S A. 2007;104:20232-7 pubmed
    ..We speculate that the kinetochore localization of Mps1 raises its local concentration, leading to its activation during mitosis through more efficient trans autophosphorylation. ..
  59. Winn J, Carter M, Avery L, Cameron S. Hox and a newly identified E2F co-repress cell death in Caenorhabditis elegans. Genetics. 2011;188:897-905 pubmed publisher
    ..Our studies demonstrate that LIN-39 and EFL-3 function in a cell type-specific context to regulate transcription of the egl-1 BH3-only cell death gene and to determine cell fate during development. ..
  60. Jokinen E, Landschulz K, Wyne K, Ho Y, Frykman P, Hobbs H. Regulation of the very low density lipoprotein receptor by thyroid hormone in rat skeletal muscle. J Biol Chem. 1994;269:26411-8 pubmed
    ..The changes in VLDL receptor mRNA in muscle were opposite to those observed with lipoprotein lipase. These studies suggest that the VLDL receptor plays a role in a metabolic process in muscle that is regulated by thyroid hormone. ..
  61. Wang C, Lindahl K. Organization and structure of the H-2M4-M8 class I genes in the mouse major histocompatibility complex. Immunogenetics. 1993;38:258-71 pubmed
    ..These genes provide probes for studying the evolution of class I genes in rodents and for the mapping and cloning of genes at the end of the distal inversion in t haplotype chromosomes. ..
  62. Hutchison M, Berman K, Cobb M. Isolation of TAO1, a protein kinase that activates MEKs in stress-activated protein kinase cascades. J Biol Chem. 1998;273:28625-32 pubmed
    ..The activation of and binding to MEK3 by TAO1 implicates TAO1 in the regulation of the p38-containing stress-responsive MAP kinase pathway. ..
  63. Hanson M, Slaughter C, Hansen E. The hbpA gene of Haemophilus influenzae type b encodes a heme-binding lipoprotein conserved among heme-dependent Haemophilus species. Infect Immun. 1992;60:2257-66 pubmed
    ..A search of GenBank for proteins with amino acid sequence similarity to HbpA revealed that the periplasmic dipeptide transport protein of E. coli, DppA, has 53% sequence identity to HbpA...
  64. Trommsdorff M, Gotthardt M, Hiesberger T, Shelton J, Stockinger W, Nimpf J, et al. Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2. Cell. 1999;97:689-701 pubmed
    ..These findings suggest that VLDLR and ApoER2 participate in transmitting the extracellular Reelin signal to intracellular signaling processes initiated by mDab1. ..
  65. Shah S, Yu G. sorLA: sorting out APP. Mol Interv. 2006;6:74-6, 58 pubmed
  66. Chen H, Karam J, Schultz R, Zhang Z, Duncan C, Hsieh J. Cloning of mouse Dab2ip gene, a novel member of the RasGTPase-activating protein family and characterization of its regulatory region in prostate. DNA Cell Biol. 2006;25:232-45 pubmed
    ..It appears that epigenetic regulation, particularly histone acetylation of the Dab2ip gene promoter, plays an important role in modulating its gene expression in the mouse prostate cancer cell. ..
  67. Liu Z, Galindo R, Wasserman S. A role for CKII phosphorylation of the cactus PEST domain in dorsoventral patterning of the Drosophila embryo. Genes Dev. 1997;11:3413-22 pubmed
    ..Taken together, these data indicate that wild-type axis formation requires CKII-catalyzed phosphorylation of the Cactus PEST domain. ..
  68. Sevrioukov E, He J, Moghrabi N, Sunio A, Kramer H. A role for the deep orange and carnation eye color genes in lysosomal delivery in Drosophila. Mol Cell. 1999;4:479-86 pubmed
    ..Furthermore, a defect in endocytic trafficking was visualized in developing photoreceptor cells. These results provide direct evidence that eye color mutations of the granule group also disrupt vesicular trafficking to lysosomes. ..
  69. Dorwart M, Shcheynikov N, Baker J, Forman Kay J, Muallem S, Thomas P. Congenital chloride-losing diarrhea causing mutations in the STAS domain result in misfolding and mistrafficking of SLC26A3. J Biol Chem. 2008;283:8711-22 pubmed publisher
    ..The data suggest that these CLD-causing mutations cause disease by at least two distinct molecular mechanisms, both ultimately leading to loss of functional protein at the plasma membrane. ..
  70. Grishin V, Grishin N. Euclidian space and grouping of biological objects. Bioinformatics. 2002;18:1523-34 pubmed
    ..The grouping procedure outperforms commonly used methods such as UPGMA and single linkage clustering. ..
  71. Lin V, Wang D, Lee I, Vasquez D, Fagelson J, McConnell J. Myosin heavy chain gene expression in normal and hyperplastic human prostate tissue. Prostate. 2000;44:193-203 pubmed
    ..Therapeutic strategies to prevent disease progression should therefore focus on early phases of prostatic growth. ..
  72. Zhang Y, Knutsen G, Brown M, Ruest L. Control of endothelin-a receptor expression by progesterone is enhanced by synergy with Gata2. Mol Endocrinol. 2013;27:892-908 pubmed publisher
    ..Together these results indicate that progesterone regulates Ednra expression by synergizing with Gata2 activity, a previously unknown mechanism. This mechanism may have an impact on pathologies involving the endothelin signaling. ..
  73. Herz J, Clouthier D, Hammer R. LDL receptor-related protein internalizes and degrades uPA-PAI-1 complexes and is essential for embryo implantation. Cell. 1992;71:411-21 pubmed
  74. Hofmann S, Topham M, Hsieh C, Francke U. cDNA and genomic cloning of HRC, a human sarcoplasmic reticulum protein, and localization of the gene to human chromosome 19 and mouse chromosome 7. Genomics. 1991;9:656-69 pubmed
    ..Of particular interest is an Alu-associated poly-d(GA) sequence located in an intron in the middle of the gene, and two stretches of acidic amino acids in the coding region of exon 1 that vary in length among different individuals. ..
  75. Madison E, Goldsmith E, Gerard R, Gething M, Sambrook J, Bassel Duby R. Amino acid residues that affect interaction of tissue-type plasminogen activator with plasminogen activator inhibitor 1. Proc Natl Acad Sci U S A. 1990;87:3530-3 pubmed
  76. Jones E, Kumanovics A, Yoshino M, Fischer Lindahl K. Mhc class I and non-class I gene organization in the proximal H2-M region of the mouse. Immunogenetics. 1999;49:183-95 pubmed
    ..These results further support the view that class I gene diverge and evolve independently between species. ..
  77. Liu Z, Spirek M, Thornton J, Butow R. A novel degron-mediated degradation of the RTG pathway regulator, Mks1p, by SCFGrr1. Mol Biol Cell. 2005;16:4893-904 pubmed
    ..We propose that Mks1p is a central player of RS and is acted upon by multiple regulators of the pathway. ..
  78. Craft C, Whitmore D, Donoso L. Differential expression of mRNA and protein encoding retinal and pineal S-antigen during the light/dark cycle. J Neurochem. 1990;55:1461-73 pubmed
    ..The differences observed in the mRNA and protein analyses suggest tissue-specific structural components for S-antigen in the retina and pineal gland that are not regulated in the same manner. ..
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