Experts and Doctors on influenza a virus in Houston, Texas, United States


Locale: Houston, Texas, United States
Topic: influenza a virus

Top Publications

  1. Maricich S, Neul J, Lotze T, Cazacu A, Uyeki T, Demmler G, et al. Neurologic complications associated with influenza A in children during the 2003-2004 influenza season in Houston, Texas. Pediatrics. 2004;114:e626-33 pubmed
  2. Sabath N, Landan G, Graur D. A method for the simultaneous estimation of selection intensities in overlapping genes. PLoS ONE. 2008;3:e3996 pubmed publisher
    ..Finally, we use our method to estimate selection in two influenza A genes for which positive selection was previously inferred. We find no evidence for positive selection in both cases. ..
  3. Zhang Y, Reynolds J, Chang S, Martin Orozco N, Chung Y, Nurieva R, et al. MKP-1 is necessary for T cell activation and function. J Biol Chem. 2009;284:30815-24 pubmed publisher
    ..Our results thus demonstrate that MKP-1 is a critical positive regulator of T cell activation and function and may be targeted in treatment of autoimmune diseases. ..
  4. El Sahly H. MF59™ as a vaccine adjuvant: a review of safety and immunogenicity. Expert Rev Vaccines. 2010;9:1135-41 pubmed publisher
    ..Currently, MF59 is under evaluation as an adjuvant with other antigens such as pandemic influenza antigens and cytomegalovirus antigens...
  5. Zheng W, Tao Y. Structure and assembly of the influenza A virus ribonucleoprotein complex. FEBS Lett. 2013;587:1206-14 pubmed publisher
    ..Recently, exciting progress has been made in studying the RNP structure and its assembly, leading to a better understanding of the structural basis of various RNP functions. ..
  6. Ni F, Mbawuike I, Kondrashkina E, Wang Q. The roles of hemagglutinin Phe-95 in receptor binding and pathogenicity of influenza B virus. Virology. 2014;450-451:71-83 pubmed publisher
    ..These results are discussed in relation to the roles of Phe-95 in receptor binding and pathogenicity of influenza B virus. ..
  7. Couch R, Atmar R, Cate T, Quarles J, Keitel W, Arden N, et al. Contrasting effects of type I interferon as a mucosal adjuvant for influenza vaccine in mice and humans. Vaccine. 2009;27:5344-8 pubmed publisher
    ..Thus, despite exhibiting a significant adjuvant effect in mice, interferon did not exhibit an adjuvant effect for induction of antibody in respiratory secretions of humans to inactivated influenza virus vaccine given intranasally. ..
  8. Gangehei L, Ali M, Zhang W, Chen Z, Wakame K, Haidari M. Oligonol a low molecular weight polyphenol of lychee fruit extract inhibits proliferation of influenza virus by blocking reactive oxygen species-dependent ERK phosphorylation. Phytomedicine. 2010;17:1047-56 pubmed publisher
    ..Our studies suggest that the underlying mechanism for the inhibitory effect of oligonol on influenza virus RNP nuclear export is blocking of ROS-dependent induction of ERK phosphorylation. ..
  9. Zhang Z, Yuan B, Lu N, Facchinetti V, Liu Y. DHX9 pairs with IPS-1 to sense double-stranded RNA in myeloid dendritic cells. J Immunol. 2011;187:4501-8 pubmed publisher
    ..Knockdown of DHX9 expression in mDCs blocked the activation of NF-?B and IFN regulatory factor 3 by dsRNA. Collectively, these results suggest that DHX9 is an important RNA sensor that is dependent on IPS-1 to sense pathogenic RNA. ..

More Information


  1. Ye Q, Guu T, Mata D, Kuo R, Smith B, Krug R, et al. Biochemical and structural evidence in support of a coherent model for the formation of the double-helical influenza A virus ribonucleoprotein. MBio. 2012;4:e00467-12 pubmed publisher
    ..Our results thus provide a coherent model for the assembly of the double-helical influenza virus RNP structure. ..
  2. Carrillo B, Choi J, Bornholdt Z, Sankaran B, Rice A, Prasad B. The influenza A virus protein NS1 displays structural polymorphism. J Virol. 2014;88:4113-22 pubmed publisher
  3. Liu H, Golebiewski L, Dow E, Krug R, Javier R, Rice A. The ESEV PDZ-binding motif of the avian influenza A virus NS1 protein protects infected cells from apoptosis by directly targeting Scribble. J Virol. 2010;84:11164-74 pubmed publisher
    ..This study shows that one function of the avian ESEV PBM is to reduce apoptosis during infection through disruption of Scribble's proapoptotic function. ..