Experts and Doctors on humans in Houston, United States

Summary

Locale: Houston, United States
Topic: humans

Top Publications

  1. Dennis J, Healy P, Beaudet A, O Brien W. Molecular definition of bovine argininosuccinate synthetase deficiency. Proc Natl Acad Sci U S A. 1989;86:7947-51 pubmed
    ..The loss of the Ava II site can be used for rapid, economical, nonradioactive detection of heterozygotes for bovine citrullinemia. ..
  2. Rodriguez J, Becker N, O Mahony C, Goss J, Aloia T. Long-term outcomes following liver transplantation for hepatic hemangioendothelioma: the UNOS experience from 1987 to 2005. J Gastrointest Surg. 2008;12:110-6 pubmed
    ..The purpose of this study was to evaluate patient and allograft survivals after liver transplantation in a large, multi-institutional cohort of patients with HEH...
  3. Humtsoe J, Feng S, Thakker G, Yang J, Hong J, Wary K. Regulation of cell-cell interactions by phosphatidic acid phosphatase 2b/VCIP. EMBO J. 2003;22:1539-54 pubmed
    ....
  4. Martin S, Cohen P, MacFarlane D, Grossman M. Cutaneous manifestations of Strongyloides stercoralis hyperinfection in an HIV-seropositive patient. Skinmed. 2011;9:199-202 pubmed
    ..Nine days later, ivermectin (4.5 mg once daily for 3 days for 2 courses) was also added. He continued to clinically deteriorate. The patient died 31 days after systemic antihelminthic treatment was initiated. ..
  5. Cotton B, Harvin J, Kostousouv V, Minei K, Radwan Z, Schöchl H, et al. Hyperfibrinolysis at admission is an uncommon but highly lethal event associated with shock and prehospital fluid administration. J Trauma Acute Care Surg. 2012;73:365-70; discussion 370 pubmed publisher
    ..To further strengthen this hypothesis, we created an in vitro hemodilution model to improve our mechanistic understanding of the early HF...
  6. Wong A, Reddy A, Williams J, Wu J, Liu D, Bruera E. ReCAP: Attitudes, Beliefs, and Awareness of Graduate Medical Education Trainees Regarding Palliative Care at a Comprehensive Cancer Center. J Oncol Pract. 2016;12:149-50; e127-37 pubmed publisher
    ..Palliative care (PC) training and integration with oncology care remain suboptimal. Current attitudes and beliefs of the oncology trainees regarding PC are not fully known. This study was undertaken in an attempt to address this issue...
  7. Bayraktar S, Gutierrez Barrera A, Lin H, Elsayegh N, Tasbas T, Litton J, et al. Outcome of metastatic breast cancer in selected women with or without deleterious BRCA mutations. Clin Exp Metastasis. 2013;30:631-42 pubmed publisher
    ..Our data indicate that BRCA1 carriers diagnosed with MBC have worse outcomes compared to BRCA2 carriers and non-carriers. However, the differences in outcome did not reach statistical significance likely due to small sample sizes. ..
  8. Johnson C, Kim I, Esmaeli B, Amin Mansour A, Treacy D, Carter S, et al. Systematic genomic and translational efficiency studies of uveal melanoma. PLoS ONE. 2017;12:e0178189 pubmed publisher
    ..Together, these studies suggest that cells expressing mutant EIF1AX may exhibit aberrant translational regulation, which may provide clonal selective advantage in the subset of uveal melanoma that harbors this mutation...
  9. Yan Q, Sun W, Kujala P, Lotfi Y, Vida T, Bean A. CART: an Hrs/actinin-4/BERP/myosin V protein complex required for efficient receptor recycling. Mol Biol Cell. 2005;16:2470-82 pubmed
    ..The novel CART complex may provide a molecular mechanism for the actin-dependence of rapid recycling of constitutively recycled plasma membrane receptors. ..
  10. Harrison D, Parisi M, Shulkin B. The Role of 18F-FDG-PET/CT in Pediatric Sarcoma. Semin Nucl Med. 2017;47:229-241 pubmed publisher
    ..Additional prospective and larger studies are needed to fully determine how best to incorporate 18F-FDG-PET/CT into treatment regimens for pediatric sarcomas in the future. ..

Locale

Detail Information

Publications62

  1. Dennis J, Healy P, Beaudet A, O Brien W. Molecular definition of bovine argininosuccinate synthetase deficiency. Proc Natl Acad Sci U S A. 1989;86:7947-51 pubmed
    ..The loss of the Ava II site can be used for rapid, economical, nonradioactive detection of heterozygotes for bovine citrullinemia. ..
  2. Rodriguez J, Becker N, O Mahony C, Goss J, Aloia T. Long-term outcomes following liver transplantation for hepatic hemangioendothelioma: the UNOS experience from 1987 to 2005. J Gastrointest Surg. 2008;12:110-6 pubmed
    ..The purpose of this study was to evaluate patient and allograft survivals after liver transplantation in a large, multi-institutional cohort of patients with HEH...
  3. Humtsoe J, Feng S, Thakker G, Yang J, Hong J, Wary K. Regulation of cell-cell interactions by phosphatidic acid phosphatase 2b/VCIP. EMBO J. 2003;22:1539-54 pubmed
    ....
  4. Martin S, Cohen P, MacFarlane D, Grossman M. Cutaneous manifestations of Strongyloides stercoralis hyperinfection in an HIV-seropositive patient. Skinmed. 2011;9:199-202 pubmed
    ..Nine days later, ivermectin (4.5 mg once daily for 3 days for 2 courses) was also added. He continued to clinically deteriorate. The patient died 31 days after systemic antihelminthic treatment was initiated. ..
  5. Cotton B, Harvin J, Kostousouv V, Minei K, Radwan Z, Schöchl H, et al. Hyperfibrinolysis at admission is an uncommon but highly lethal event associated with shock and prehospital fluid administration. J Trauma Acute Care Surg. 2012;73:365-70; discussion 370 pubmed publisher
    ..To further strengthen this hypothesis, we created an in vitro hemodilution model to improve our mechanistic understanding of the early HF...
  6. Wong A, Reddy A, Williams J, Wu J, Liu D, Bruera E. ReCAP: Attitudes, Beliefs, and Awareness of Graduate Medical Education Trainees Regarding Palliative Care at a Comprehensive Cancer Center. J Oncol Pract. 2016;12:149-50; e127-37 pubmed publisher
    ..Palliative care (PC) training and integration with oncology care remain suboptimal. Current attitudes and beliefs of the oncology trainees regarding PC are not fully known. This study was undertaken in an attempt to address this issue...
  7. Bayraktar S, Gutierrez Barrera A, Lin H, Elsayegh N, Tasbas T, Litton J, et al. Outcome of metastatic breast cancer in selected women with or without deleterious BRCA mutations. Clin Exp Metastasis. 2013;30:631-42 pubmed publisher
    ..Our data indicate that BRCA1 carriers diagnosed with MBC have worse outcomes compared to BRCA2 carriers and non-carriers. However, the differences in outcome did not reach statistical significance likely due to small sample sizes. ..
  8. Johnson C, Kim I, Esmaeli B, Amin Mansour A, Treacy D, Carter S, et al. Systematic genomic and translational efficiency studies of uveal melanoma. PLoS ONE. 2017;12:e0178189 pubmed publisher
    ..Together, these studies suggest that cells expressing mutant EIF1AX may exhibit aberrant translational regulation, which may provide clonal selective advantage in the subset of uveal melanoma that harbors this mutation...
  9. Yan Q, Sun W, Kujala P, Lotfi Y, Vida T, Bean A. CART: an Hrs/actinin-4/BERP/myosin V protein complex required for efficient receptor recycling. Mol Biol Cell. 2005;16:2470-82 pubmed
    ..The novel CART complex may provide a molecular mechanism for the actin-dependence of rapid recycling of constitutively recycled plasma membrane receptors. ..
  10. Harrison D, Parisi M, Shulkin B. The Role of 18F-FDG-PET/CT in Pediatric Sarcoma. Semin Nucl Med. 2017;47:229-241 pubmed publisher
    ..Additional prospective and larger studies are needed to fully determine how best to incorporate 18F-FDG-PET/CT into treatment regimens for pediatric sarcomas in the future. ..
  11. Lipton A, Chapman J, Leitzel K, Garg A, Pritchard K, Ingle J, et al. Osteoporosis therapy and outcomes for postmenopausal patients with hormone receptor-positive breast cancer: NCIC CTG MA.27. Cancer. 2017;123:2444-2451 pubmed publisher
    ..AIs increase the risk of osteoporosis. This study examined the effects of self-reported osteoporosis and osteoporosis therapy (OPT) on outcomes...
  12. Kwok S, Matorin A, Kahn D. Clinical and ethical dilemmas in the psychiatric care of patients who border on the edge of being able to live safely and independently. J Psychiatr Pract. 2012;18:213-20 pubmed publisher
    ..This article uses a case presentation to highlight this struggle at the interface of psychiatry, ethics, and the emergency room in the care of people with severe mental illness. ..
  13. Kantarjian H, Giles F, Greenberg P, Paquette R, Wang E, Gabrilove J, et al. Phase 2 study of romiplostim in patients with low- or intermediate-risk myelodysplastic syndrome receiving azacitidine therapy. Blood. 2010;116:3163-70 pubmed publisher
    ..0035) compared with placebo. Grade 3 rash and arthralgia each were reported in 1 romiplostim-treated patient (4%). This study suggests romiplostim may provide clinical benefits in MDS patients during azacitidine therapy. ..
  14. BUCASAS K, Pandya G, Pradhan S, Fleischmann R, Peterson S, Belmont J. Assessing the utility of whole-genome amplified serum DNA for array-based high throughput genotyping. BMC Genet. 2009;10:85 pubmed publisher
    ....
  15. Feng S, Agoulnik I, Li Z, Han H, Lopez Berestein G, Sood A, et al. Relaxin/RXFP1 signaling in prostate cancer progression. Ann N Y Acad Sci. 2009;1160:379-80 pubmed publisher
    ..Suppression of RXFP1 expression in PC3 xenografts in nude mice by intratumoral injections of short interfering RNA resulted in decreased tumor size, cell proliferation, and metastasis rate. ..
  16. St Clair N, Pitt M, Bakeera Kitaka S, McCall N, Lukolyo H, Arnold L, et al. Global Health: Preparation for Working in Resource-Limited Settings. Pediatrics. 2017;140: pubmed publisher
    ..Suggestions are made for the health care community to develop and implement widely endorsed preparation standards for trainees, clinicians, and organizations engaging in GH experiences and partnerships...
  17. Wei Q, Xu X, Cheng L, Legerski R, Ali Osman F. Simultaneous amplification of four DNA repair genes and beta-actin in human lymphocytes by multiplex reverse transcriptase-PCR. Cancer Res. 1995;55:5025-9 pubmed
    ..This approach should facilitate molecular epidemiological studies that incorporate screening for germline alterations that may affect gene expression and for changes in the levels of gene expression. ..
  18. Raveendran M, Senthil D, Utama B, Shen Y, Dudley D, Wang J, et al. Cigarette suppresses the expression of P4Halpha and vascular collagen production. Biochem Biophys Res Commun. 2004;323:592-8 pubmed
    ....
  19. Fraizer G, Shimamura R, Zhang X, Saunders G. PAX 8 regulates human WT1 transcription through a novel DNA binding site. J Biol Chem. 1997;272:30678-87 pubmed
    ..Thus, we identified a novel functional binding site for the transcription factor PAX 8, suggesting that part of its role in kidney development may be as a modulator of WT1 expression in the kidney. ..
  20. Taddei I, Morishima M, Huynh T, Lindsay E. Genetic factors are major determinants of phenotypic variability in a mouse model of the DiGeorge/del22q11 syndromes. Proc Natl Acad Sci U S A. 2001;98:11428-31 pubmed
    ..These data provide a framework for our understanding of phenotypic variability in patients with del22q11 syndrome and the tools for its genetic dissection. ..
  21. Young E, Zheng Z, Wilkins A, Jeong H, Li M, Lichtarge O, et al. Regulation of Ras localization and cell transformation by evolutionarily conserved palmitoyltransferases. Mol Cell Biol. 2014;34:374-85 pubmed publisher
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  22. Bean A, Davanger S, Chou M, Gerhardt B, Tsujimoto S, Chang Y. Hrs-2 regulates receptor-mediated endocytosis via interactions with Eps15. J Biol Chem. 2000;275:15271-8 pubmed
    ..These data show that Hrs-2 regulates endocytosis, delineate a biochemical pathway (Hrs-2-Eps15-AP2) in which Hrs-2 functions, and suggest that Hrs-2 acts to provide communication between endo- and exocytic processes. ..
  23. Liu W, Li Y, Li X, Cao W, Zhang X. Influence of robust optimization in intensity-modulated proton therapy with different dose delivery techniques. Med Phys. 2012;39:3089-101 pubmed publisher
    ..They also compared conventional and robust optimization of IMPT-DET with three-dimensional IMPT (IMPT-3D) to gain understanding about how plan robustness is achieved...
  24. Carthon B, Wolchok J, Yuan J, Kamat A, Ng Tang D, Sun J, et al. Preoperative CTLA-4 blockade: tolerability and immune monitoring in the setting of a presurgical clinical trial. Clin Cancer Res. 2010;16:2861-71 pubmed publisher
    ..Our group conducted the first preoperative clinical trial with the anti-CTLA-4 antibody ipilimumab in 12 patients with localized urothelial carcinoma of the bladder...
  25. Dharmat R, Liu W, Ge Z, Sun Z, Yang L, Li Y, et al. IFT81 as a Candidate Gene for Nonsyndromic Retinal Degeneration. Invest Ophthalmol Vis Sci. 2017;58:2483-2490 pubmed publisher
    ..This represents the first report of mutations in IFT81 as a candidate gene for nonsyndromic retinal dystrophy, hence expanding the phenotype spectrum of IFT-B components. ..
  26. Peintinger F, Buzdar A, Kuerer H, Mejia J, Hatzis C, Gonzalez Angulo A, et al. Hormone receptor status and pathologic response of HER2-positive breast cancer treated with neoadjuvant chemotherapy and trastuzumab. Ann Oncol. 2008;19:2020-5 pubmed publisher
    ..Patients with HR+/HER2+ breast cancer obtained significant benefit from addition of trastuzumab to P/FEC chemotherapy; pathologic response rate was similar to that seen in HR-/HER2+ breast cancers. ..
  27. Qin L, Liao L, Redmond A, Young L, Yuan Y, Chen H, et al. The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression. Mol Cell Biol. 2008;28:5937-50 pubmed publisher
    ..These findings suggest a new alternative strategy for controlling the deleterious roles of these MMPs in breast cancer by inhibiting their upstream coregulator AIB1. ..
  28. Luke K, Perham M, Wittung Stafshede P. Kinetic folding and assembly mechanisms differ for two homologous heptamers. J Mol Biol. 2006;363:729-42 pubmed
    ..This study demonstrates that molecular details can overrule similarity of native-state topology in defining apparent protein-biophysical properties. ..
  29. Dugan T, Yang V, McQuillan D, Hook M. Decorin modulates fibrin assembly and structure. J Biol Chem. 2006;281:38208-16 pubmed
    ..Collectively, these data demonstrate that decorin can regulate fibrin organization and reveal a novel mechanism by which extracellular matrix components can participate in hemostasis, thrombosis, and wound repair. ..
  30. Pathak S, Multani A, Banerji P, Banerji P. Ruta 6 selectively induces cell death in brain cancer cells but proliferation in normal peripheral blood lymphocytes: A novel treatment for human brain cancer. Int J Oncol. 2003;23:975-82 pubmed
    ..Cancer cell death was initiated by telomere erosion and completed through mitotic catastrophe events. We propose that Ruta in combination with Ca3(PO4)2 could be used for effective treatment of brain cancers, particularly glioma...
  31. Rao S, Huang S, Glenn St Hilaire B, Engreitz J, Perez E, Kieffer Kwon K, et al. Cohesin Loss Eliminates All Loop Domains. Cell. 2017;171:305-320.e24 pubmed publisher
    ..We then restore cohesin and monitor the re-formation of each loop. Although re-formation rates vary greatly, many megabase-sized loops recovered in under an hour, consistent with a model where loop extrusion is rapid...
  32. Hotez P. The Four Horsemen of the Apocalypse: Tropical Medicine in the Fight against Plague, Death, Famine, and War. Am J Trop Med Hyg. 2012;87:3-10 pubmed publisher
  33. Liu Q, Guntuku S, Cui X, Matsuoka S, Cortez D, Tamai K, et al. Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint. Genes Dev. 2000;14:1448-59 pubmed
    ..Taken together, these data indicate that Chk1 plays an essential role in the mammalian DNA damage checkpoint, embryonic development, and tumor suppression, and that Atr regulates Chk1. ..
  34. Wei H, Ke H, Lin J, Shete S, Wood C, Hildebrandt M. MicroRNA target site polymorphisms in the VHL-HIF1α pathway predict renal cell carcinoma risk. Mol Carcinog. 2014;53:1-7 pubmed publisher
    ..These novel genetic risk factors might help identify individuals at high risk to enable detection of tumors at an early, curable stage. ..
  35. Gollob M, Green M, Tang A, Gollob T, Karibe A, Ali Hassan A, et al. Identification of a gene responsible for familial Wolff-Parkinson-White syndrome. N Engl J Med. 2001;344:1823-31 pubmed
    ..Further understanding of how this molecular defect leads to supraventricular arrhythmias could influence the development of specific therapies for other forms of supraventricular arrhythmia. ..
  36. Greenberg S. Serious waterborne and wilderness infections. Crit Care Clin. 1999;15:387-414 pubmed
    ..Pathogens causing serious infections include bacteria, fungi, viruses, and protozoa. Epidemiologic help can be obtained from local or state health departments as well as the Centers for Disease Control...
  37. Lachar D, Bailley S, Rhoades H, Espadas A, Aponte M, Cowan K, et al. New subscales for an anchored version of the Brief Psychiatric Rating Scale: construction, reliability, and validity in acute psychiatric admissions. Psychol Assess. 2001;13:384-95 pubmed
    ..Application of the BPRS-A as a debriefing instrument in the study of symptomatic change and the multiple challenges inherent in psychometric study of such a rating scale in realistic hospital practice are discussed. ..
  38. Abd Elgaliel W, Tung C. Selective detection of Cathepsin E proteolytic activity. Biochim Biophys Acta. 2010;1800:1002-8 pubmed publisher
    ..This study forms the foundation of Cath E specific inhibitor development in further studies. ..
  39. Hatef E, Roberts D, McLaughlin P, Pro B, Esmaeli B. Prevalence and nature of systemic involvement and stage at initial examination in patients with orbital and ocular adnexal lymphoma. Arch Ophthalmol. 2007;125:1663-7 pubmed
    ..To determine the stage at initial examination and the prevalence of systemic involvement in patients with orbital and ocular adnexal lymphoma...
  40. Deng L, Sundriyal S, Rubio V, Shi Z, Song Y. Coordination chemistry based approach to lipophilic inhibitors of 1-deoxy-D-xylulose-5-phosphate reductoisomerase. J Med Chem. 2009;52:6539-42 pubmed publisher
    ..4 microM. It exhibited a broad spectrum of activity against Gram-negative and -positive bacteria with minimal inhibition concentrations of 20-100 microM (or 3.7-19 microg/mL). ..
  41. Shan W, Liu J. Inflammation: a hidden path to breaking the spell of ovarian cancer. Cell Cycle. 2009;8:3107-11 pubmed
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  42. Song C, Wen W, Rayala S, Chen M, Ma J, Zhang M, et al. Serine 88 phosphorylation of the 8-kDa dynein light chain 1 is a molecular switch for its dimerization status and functions. J Biol Chem. 2008;283:4004-13 pubmed
    ....
  43. Cardoso F, Costa A, Norton L, Senkus E, Aapro M, Andre F, et al. ESO-ESMO 2nd international consensus guidelines for advanced breast cancer (ABC2)†. Ann Oncol. 2014;25:1871-88 pubmed publisher
  44. Wang C, Gu C, Jeong K, Zhang D, Guo W, Lu Y, et al. YAP/TAZ-Mediated Upregulation of GAB2 Leads to Increased Sensitivity to Growth Factor-Induced Activation of the PI3K Pathway. Cancer Res. 2017;77:1637-1648 pubmed publisher
    ..The cross-talk between these key pathways identifies potential new biomarkers and therapeutic targets in endometrial cancer. Cancer Res; 77(7); 1637-48. ©2017 AACR. ..
  45. Zhang N, Kaur R, Lu X, Shen X, Li L, Legerski R. The Pso4 mRNA splicing and DNA repair complex interacts with WRN for processing of DNA interstrand cross-links. J Biol Chem. 2005;280:40559-67 pubmed
    ..In addition, we show that WRN and the Pso4 complex interact through a direct physical association between WRN and Cdc5L. A putative model for uncoupling of ICLs in mammalian cells is presented. ..
  46. Zhao Z, Lee C, Jiralerspong S, Juyal R, Lu F, Baldini A, et al. The gene for a human microfibril-associated glycoprotein is commonly deleted in Smith-Magenis syndrome patients. Hum Mol Genet. 1995;4:589-97 pubmed
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  47. Wiszniewski W, Hunter J, Hanchard N, Willer J, Shaw C, Tian Q, et al. TM4SF20 ancestral deletion and susceptibility to a pediatric disorder of early language delay and cerebral white matter hyperintensities. Am J Hum Genet. 2013;93:197-210 pubmed publisher
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  48. Shiralkar M, Harris T, Eddins Folensbee F, Coverdale J. A systematic review of stress-management programs for medical students. Acad Psychiatry. 2013;37:158-64 pubmed publisher
    ..Significant opportunities to advance educational research in this field exist by developing more high-quality studies with particular attention to randomization techniques and standardizing outcome measures. ..
  49. Willmroth F, Beaudet A. Structure of the murine E-selectin ligand 1 (ESL-1) gene and assignment to Chromosome 8. Mamm Genome. 1999;10:1085-8 pubmed
    ..It maps to murine Chromosome (Chr) 8 in a region homologous to human Chr 16q where the GLG1 locus maps, further indicating that Selel and GLG1 are mouse and human equivalents of the same gene. ..
  50. Gu Z, Li Y, Lee P, Liu T, Wan C, Wang Z. Protein arginine methyltransferase 5 functions in opposite ways in the cytoplasm and nucleus of prostate cancer cells. PLoS ONE. 2012;7:e44033 pubmed publisher
    ..These results imply a novel mechanism by which PRMT5 controls cell growth and contributes to prostate tumorigenesis. ..
  51. Dai Y, Zhang W, Wen J, Zhang Y, Kellems R, Xia Y. A2B adenosine receptor-mediated induction of IL-6 promotes CKD. J Am Soc Nephrol. 2011;22:890-901 pubmed publisher
    ..Taken together, these data suggest that A(2B)R-mediated induction of IL-6 contributes to renal fibrogenesis and shows potential therapeutic targets for CKD. ..
  52. Nicoloso M, Sun H, Spizzo R, Kim H, Wickramasinghe P, Shimizu M, et al. Single-nucleotide polymorphisms inside microRNA target sites influence tumor susceptibility. Cancer Res. 2010;70:2789-98 pubmed publisher
    ..Therefore, we propose that transcribed target SNPs alter miRNA gene regulation and, consequently, protein expression, contributing to the likelihood of cancer susceptibility, by a novel mechanism of subtle gene regulation. ..
  53. Dakhova O, Ozen M, Creighton C, Li R, Ayala G, Rowley D, et al. Global gene expression analysis of reactive stroma in prostate cancer. Clin Cancer Res. 2009;15:3979-89 pubmed publisher
    ..Formation of reactive stroma in prostate cancer is a dynamic process characterized by significant alterations in growth factor and signal transduction pathways and formation of new structures, including nerves and axons. ..
  54. Wu M, Wang M, Nix J, Hryshko L, Zheng L. Crystal structure of CBD2 from the Drosophila Na(+)/Ca(2+) exchanger: diversity of Ca(2+) regulation and its alternative splicing modification. J Mol Biol. 2009;387:104-12 pubmed publisher
    ....
  55. Yu Y, Ge N, Xie M, Sun W, Burlingame S, Pass A, et al. Phosphorylation of Thr-178 and Thr-184 in the TAK1 T-loop is required for interleukin (IL)-1-mediated optimal NFkappaB and AP-1 activation as well as IL-6 gene expression. J Biol Chem. 2008;283:24497-505 pubmed publisher
    ..Our finding is the first report that substitution of key serine/threonine residues with acidic residues mimics the phosphorylated state of TAK1 and renders TAK1 active during its induced activation. ..
  56. Singh M, Howard A, Irwin M, Gao Y, Lu X, Multani A, et al. Expression and activity of Fyn mediate proliferation and blastic features of chronic myelogenous leukemia. PLoS ONE. 2012;7:e51611 pubmed publisher
    ..Together, these results reveal a novel role for Fyn in regulating events required for genomic maintenance and suggest that Fyn kinase activity plays a role in the progression of CML to blast crisis. ..
  57. Escott Price V, Bellenguez C, Wang L, Choi S, Harold D, Jones L, et al. Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease. PLoS ONE. 2014;9:e94661 pubmed publisher
    ....
  58. Chagpar R, Xing Y, Chiang Y, Feig B, Chang G, You Y, et al. Adherence to stage-specific treatment guidelines for patients with colon cancer. J Clin Oncol. 2012;30:972-9 pubmed publisher
    ..Significant variation exists in the treatment of colon cancer, particularly in treatment of high-risk stage II and stage III disease. The impact of nonadherence to guidelines on patient outcomes needs to be further elucidated. ..
  59. Li L, Peterson C, Kanter Smoler G, Wei Y, Ramagli L, Sunnerhagen P, et al. hRAD17, a structural homolog of the Schizosaccharomyces pombe RAD17 cell cycle checkpoint gene, stimulates p53 accumulation. Oncogene. 1999;18:1689-99 pubmed
    ..Using FISH analysis, we have mapped the hRAD17 locus to human chromosome 5q11.2. ..
  60. Giza D, Iliescu G, Hassan S, Marmagkiolis K, Iliescu C. Cancer as a Risk Factor for Cardiovascular Disease. Curr Oncol Rep. 2017;19:39 pubmed publisher
    ..Better knowledge of these early and late cardiac effects in cancer patients will enable adoption of both primary and secondary prevention measures of long-term treatment complications in cancer survivors. ..
  61. Ekmekcioglu S, Ellerhorst J, Mumm J, Zheng M, Broemeling L, Prieto V, et al. Negative association of melanoma differentiation-associated gene (mda-7) and inducible nitric oxide synthase (iNOS) in human melanoma: MDA-7 regulates iNOS expression in melanoma cells. Mol Cancer Ther. 2003;2:9-17 pubmed
    ..These studies demonstrate that expression of the MDA-7 tumor suppressor can negatively regulate iNOS expression in malignant melanoma cell lines. ..
  62. Schroeder W, Stewart Galetka S, Mandavilli S, Parry D, Goldsmith L, Duvic M. Cloning and characterization of a novel epidermal cell surface antigen (ESA). J Biol Chem. 1994;269:19983-91 pubmed
    ....