Experts and Doctors on ubiquitin protein ligase complexes in Nashville, Tennessee, United States

Summary

Locale: Nashville, Tennessee, United States
Topic: ubiquitin protein ligase complexes

Top Publications

  1. Berry L, Feoktistova A, Wright M, Gould K. The schizosaccharomyces pombe dim1(+) gene interacts with the anaphase-promoting complex or cyclosome (APC/C) component lid1(+) and is required for APC/C function. Mol Cell Biol. 1999;19:2535-46 pubmed
    ..These data suggest that at least one role of dim1p is to maintain or establish the steady-state level of the APC/C. ..
  2. Yoon H, Feoktistova A, Chen J, Jennings J, Link A, Gould K. Role of Hcn1 and its phosphorylation in fission yeast anaphase-promoting complex/cyclosome function. J Biol Chem. 2006;281:32284-93 pubmed
    ..Phosphorylation of Hcn1 occurs at a single Cdk1 site in vitro and in vivo. Mutation of this site to alanine, but not aspartic acid, compromises APC/C function and leads to a specific defect in the completion of cell division. ..
  3. Chang L, Morrell J, Feoktistova A, Gould K. Study of cyclin proteolysis in anaphase-promoting complex (APC) mutant cells reveals the requirement for APC function in the final steps of the fission yeast septation initiation network. Mol Cell Biol. 2001;21:6681-94 pubmed
    ..Indeed, overproduction of nondestructible Cdc13p prevents septation in APC cut mutants and the normal reorganization of septation initiation network components during anaphase. ..