Experts and Doctors on piperidines in Memphis, Tennessee, United States
Locale: Memphis, Tennessee, United States
Salles J, Wallace M, Fain J. Differential effects of alkylating agents on the multiple muscarinic receptor subtypes linked to activation of phospholipase C by carbachol in rat brain cortical membranes. J Pharmacol Exp Ther. 1993;264:521-9 pubmed
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Broniscer A, Baker S, Wetmore C, Pai Panandiker A, Huang J, Davidoff A, et al
. Phase I trial, pharmacokinetics, and pharmacodynamics of vandetanib and dasatinib in children with newly diagnosed diffuse intrinsic pontine glioma. Clin Cancer Res. 2013;19:3050-8 pubmed publisher
..The MTD of vandetanib and dasatinib in combination was 65 mg/m(2) for each drug. Other studies are underway to test dasatinib and other PDGFR inhibitors alone or in combination for this deadly cancer. ..
Tipton D, Lewis J. Effects of a hindered amine light stabilizer and a UV light absorber used in maxillofacial elastomers on human gingival epithelial cells and fibroblasts. J Prosthet Dent. 2008;100:220-31 pubmed publisher
Wang L, Armstrong W. Tonic regulation of GABAergic synaptic activity on vasopressin neurones by cannabinoids. J Neuroendocrinol. 2012;24:664-73 pubmed publisher
Marshall A, Lagutina I, Grosveld G. PAX3-FOXO1 induces cannabinoid receptor 1 to enhance cell invasion and metastasis. Cancer Res. 2011;71:7471-80 pubmed publisher
..Cnr1 loss by either route also dramatically reduced lung metastasis formation. Taken together, our findings strongly implicate Cnr1 as a novel tractable target to inhibit ARMS invasion and metastasis. ..
Blundon J, Roy N, Teubner B, Yu J, Eom T, Sample K, et al
. Restoring auditory cortex plasticity in adult mice by restricting thalamic adenosine signaling. Science. 2017;356:1352-1356 pubmed publisher
..We conclude that, in adult mice, disrupting adenosine signaling in the thalamus rejuvenates plasticity in the auditory cortex and improves auditory perception. ..