Experts and Doctors on auditory cortex in Memphis, Tennessee, United States
Locale: Memphis, Tennessee, United States
Topic: auditory cortex
Chun S, Bayazitov I, Blundon J, Zakharenko S. Thalamocortical long-term potentiation becomes gated after the early critical period in the auditory cortex. J Neurosci. 2013;33:7345-57 pubmed publisher
..These data indicate that TC LTP in the ACx persists throughout life and therefore can potentially contribute to experience-dependent cortical map plasticity in the ACx in both young and adult animals. ..
Bayazitov I, Westmoreland J, Zakharenko S. Forward suppression in the auditory cortex is caused by the Ca(v)3.1 calcium channel-mediated switch from bursting to tonic firing at thalamocortical projections. J Neurosci. 2013;33:18940-50 pubmed publisher
..These data suggest that Ca(v)3.1-dependent synaptic depression at TC projections contributes to mechanisms of forward suppression in the ACx. ..
Chun S, Westmoreland J, Bayazitov I, Eddins D, Pani A, Smeyne R, et al
. Specific disruption of thalamic inputs to the auditory cortex in schizophrenia models. Science. 2014;344:1178-82 pubmed publisher
..This suggests that Dgcr8-microRNA-Drd2-dependent thalamocortical disruption is a pathogenic event underlying schizophrenia-associated psychosis. ..
Blundon J, Roy N, Teubner B, Yu J, Eom T, Sample K, et al
. Restoring auditory cortex plasticity in adult mice by restricting thalamic adenosine signaling. Science. 2017;356:1352-1356 pubmed publisher
..We conclude that, in adult mice, disrupting adenosine signaling in the thalamus rejuvenates plasticity in the auditory cortex and improves auditory perception. ..