Experts and Doctors on pregnancy in Providence, Rhode Island, United States

Summary

Locale: Providence, Rhode Island, United States
Topic: pregnancy

Top Publications

  1. Wilde D, Marshall J. Effects of tetraethylammonium and 4-aminopyridine on the plateau potential of circular myometrium from the pregnant rat. Biol Reprod. 1988;38:836-45 pubmed
    ..The plateau potential may result from an outwardly rectifying TEA-sensitive current combined with a slow inward current, the plateau magnitude being determined by the relative intensity of each current...
  2. McGowan E, Kostadinov S, McLean K, Gotsch F, Venturini D, Romero R, et al. Placental IL-10 dysregulation and association with bronchopulmonary dysplasia risk. Pediatr Res. 2009;66:455-60 pubmed publisher
    ..01-0.70, p = 0.02). These results suggest that a placental balance between inflammatory and anti-inflammatory cytokines is crucial to normal lung organogenesis. Importantly, IL-10 seems to be protective against the development of BPD. ..
  3. LaRocca J, Boyajian A, Brown C, Smith S, Hixon M. Effects of in utero exposure to Bisphenol A or diethylstilbestrol on the adult male reproductive system. Birth Defects Res B Dev Reprod Toxicol. 2011;92:526-33 pubmed publisher
    ..At the molecular level, in utero exposure to DES, but not BPA, leads to decreased mRNA expression of genes associated with Sertoli cell differentiation. ..
  4. Johnson J, Anderson B, Pass R. Prevention of maternal and congenital cytomegalovirus infection. Clin Obstet Gynecol. 2012;55:521-30 pubmed publisher
    ..Vaccines for CMV are under development but it will be a number of years before one is licensed. ..
  5. Yang J, Brown A, Ellisor D, Paul E, Hagan N, Zervas M. Dynamic temporal requirement of Wnt1 in midbrain dopamine neuron development. Development. 2013;140:1342-52 pubmed publisher
    ..Collectively, our analyses resolve the spatial and temporal function of Wnt1 in Mb and Cb patterning and in MbDA neuron development in vivo. ..
  6. Stonestreet B, Elitt C, Markowitz J, Petersson K, Sadowska G. Effects of antenatal corticosteroids on regional brain and non-neural tissue water content in the ovine fetus. J Soc Gynecol Investig. 2003;10:59-66 pubmed
    ..This corticosteroid treatment regimen was also associated with decreased regional non-neural tissue water content at 60%, 80%, and 90% of gestation. ..
  7. Kalkunte S, Lai Z, Norris W, Pietras L, Tewari N, Boij R, et al. Novel approaches for mechanistic understanding and predicting preeclampsia. J Reprod Immunol. 2009;83:134-8 pubmed publisher
    ..This review attempts to address some of these issues and discuss the signature biochemical serum factors and propose new and better ways to predict PE. ..
  8. Maccarthy S, Rasanathan J, Ferguson L, Gruskin S. The pregnancy decisions of HIV-positive women: the state of knowledge and way forward. Reprod Health Matters. 2012;20:119-40 pubmed publisher
    ..It is critical that HIV-positive women be more involved in the design and implementation of research, policies and programs related to their pregnancy-related needs and rights. ..
  9. Johnson J, Anderson B. Cytomegalovirus: should we screen pregnant women for primary infection?. Am J Perinatol. 2013;30:121-4 pubmed publisher
    ..More evidence from randomized controlled trials is needed prior to moving forward with a screening program for congenital CMV. ..

More Information

Publications191 found, 100 shown here

  1. Abar B, Lagasse L, Wouldes T, Derauf C, Newman E, Shah R, et al. Cross-national comparison of prenatal methamphetamine exposure on infant and early child physical growth: a natural experiment. Prev Sci. 2014;15:767-76 pubmed publisher
    ..Effects of PME on infant and child growth were shown to differ across countries, with exposed children in NZ faring better than exposed children in the USA. Implications for prevention programs and public policy are discussed. ..
  2. Washington B, Raker C, Kabeja G, Kay A, Hampton B. Demographic and delivery characteristics associated with obstetric fistula in Kigali, Rwanda. Int J Gynaecol Obstet. 2015;129:34-7 pubmed publisher
    ..2). Approximately half of the women in the sample delivered by cesarean, and these women were more likely to have a fistula involving the uterus or cervix. ..
  3. Olveda R, Acosta L, Tallo V, Baltazar P, Lesiguez J, Estanislao G, et al. Efficacy and safety of praziquantel for the treatment of human schistosomiasis during pregnancy: a phase 2, randomised, double-blind, placebo-controlled trial. Lancet Infect Dis. 2016;16:199-208 pubmed publisher
    ..National Institutes of Health, National Institute of Allergy and Infectious Diseases (U01AI066050). ..
  4. Vuong A, Yolton K, Webster G, Sjödin A, Calafat A, Braun J, et al. Prenatal polybrominated diphenyl ether and perfluoroalkyl substance exposures and executive function in school-age children. Environ Res. 2016;147:556-64 pubmed publisher
    ..38, 95% CI 0.86, 5.90). However, no association was observed between perfluorooctanoate (PFOA) and executive function. Prenatal exposures to BDE-153 and PFOS may be associated with executive function deficits in school-age children. ..
  5. Romano M, Enquobahrie D, Simpson C, Checkoway H, Williams M. Maternal body burden of cadmium and offspring size at birth. Environ Res. 2016;147:461-8 pubmed publisher
    ..001; β(95% CI): female=-0.47cm (-0.74, -0.20), male=0.32cm (0.00, 0.65)]. Our findings suggest potential sex-specific reversal of Cd's associations on birth length and contribute to the evidence suggesting Cd impairs fetal growth. ..
  6. Jayakrishnan A, Vrees R, Anderson B. Varicella zoster meningitis in a pregnant woman with acquired immunodeficiency syndrome. Am J Perinatol. 2008;25:573-5 pubmed publisher
    ..Early diagnosis and initiation of appropriate treatment may provide an opportunity to improve both maternal and fetal outcomes...
  7. Gyuris A, Donovan D, Seymour K, Lovasco L, Smilowitz N, Halperin A, et al. The chromatin-targeting protein Brd2 is required for neural tube closure and embryogenesis. Biochim Biophys Acta. 2009;1789:413-21 pubmed publisher
    ..Together these results implicate essential roles for Brd2 as a critical integrator of chromatin structure and transcription during mammalian embryogenesis and neurogenesis. ..
  8. Moore R, Miller M, Eklund E, Lu K, Bast R, Lambert Messerlian G. Serum levels of the ovarian cancer biomarker HE4 are decreased in pregnancy and increase with age. Am J Obstet Gynecol. 2012;206:349.e1-7 pubmed publisher
    ..001). HE4 serum concentrations vary significantly on the basis of age. These variations must be considered when the upper limit of normal for HE4 is determined. ..
  9. Smith C, Saftlas A, Spracklen C, Triche E, Bjonnes A, Keating B, et al. Genetic Risk Score for Essential Hypertension and Risk of Preeclampsia. Am J Hypertens. 2016;29:17-24 pubmed publisher
    ..GRSs for hypertension and blood pressure are not associated with preeclampsia, suggesting that an underlying predisposition to essential hypertension is not on the causal pathway of preeclampsia. ..
  10. Carpenter M, Canick J, Hogan J, Shellum C, Somers M, Star J. Amniotic fluid insulin at 14-20 weeks' gestation: association with later maternal glucose intolerance and birth macrosomia. Diabetes Care. 2001;24:1259-63 pubmed
    ..Among gravidas with GCT values > 7.2 mmol/l, elevated early AF insulin concentration is associated with fetal macrosomia. Maternal glucose intolerance may affect fetal insulin production before 20 weeks' gestation. ..
  11. Ji H, Dailey T, Long V, Chien E. Prostaglandin E2-regulated cervical ripening: analysis of proteoglycan expression in the rat cervix. Am J Obstet Gynecol. 2008;198:536.e1-7 pubmed publisher
    ..The decrease in sulfated GAG could decrease electrostatic interactions that would weaken interfibrillar interactions. These findings would be consistent with a decline in cervical resistance. ..
  12. O BRIEN K, Sekimoto H, Boney C, Malee M. Effect of fetal dexamethasone exposure on the development of adult insulin sensitivity in a rat model. J Matern Fetal Neonatal Med. 2008;21:623-8 pubmed publisher
    ..This effect did not appear to be enhanced by administration of insulin prior to sacrifice, nor was a sex-dependent differential effect noted. ..
  13. Haddow J, Cleary Goldman J, McClain M, Palomaki G, Neveux L, Lambert Messerlian G, et al. Thyroperoxidase and thyroglobulin antibodies in early pregnancy and preterm delivery. Obstet Gynecol. 2010;116:58-62 pubmed publisher
    ..Preterm premature rupture of membranes appears to contribute to the thyroid antibody-associated early deliveries, possibly as a result of inflammation. II. ..
  14. Padbury J, Tseng Y, McGonnigal B, Penado K, Stephan M, Rudnick G. Placental biogenic amine transporters: cloning and expression. Brain Res Mol Brain Res. 1997;45:163-8 pubmed
    ..We suggest the exaggerated fetal vulnerability to uptake inhibitors, like cocaine, may be due to blockade of placental biogenic amine transport. ..
  15. Sanchez Esteban J, Wang Y, Gruppuso P, Rubin L. Mechanical stretch induces fetal type II cell differentiation via an epidermal growth factor receptor-extracellular-regulated protein kinase signaling pathway. Am J Respir Cell Mol Biol. 2004;30:76-83 pubmed
    ..These results suggest that EGFR may be a mechanosensor during fetal lung development. These findings may have significant implications for the design of strategies to accelerate lung maturation. ..
  16. Gruppuso P, Boylan J, Anand P, Bienieki T. Effects of maternal starvation on hepatocyte proliferation in the late gestation fetal rat. Pediatr Res. 2005;57:185-91 pubmed
    ..Our results are consistent with the hypothesis that restricted nutrient availability signals to the hepatocyte cell cycle in fetuses of fasted mothers, thereby accounting for decreased hepatocyte proliferation and liver mass. ..
  17. Chrostowski M, McGonnigal B, Stabila J, Padbury J. LAT-1 expression in pre- and post-implantation embryos and placenta. Placenta. 2009;30:270-6 pubmed publisher
    ..The mechanism of LAT-1 regulation during placentation, therefore, might provide valuable clues to its role in tumor progression and invasion. ..
  18. Paglia M, Coustan D. The use of oral antidiabetic medications in gestational diabetes mellitus. Curr Diab Rep. 2009;9:287-90 pubmed
    ..However, both agents have been shown to cross the placenta to the fetus, and thus they should be used with caution and patients counseled appropriately. ..
  19. Hunter L. Exploring the role of uterine artery embolization in the management of postpartum hemorrhage. J Perinat Neonatal Nurs. 2010;24:207-14 pubmed publisher
    ..The technical aspects of this procedure, reported complications, and effects on future fertility are described. The prophylactic use of intra-arterial balloon catheters in the management of abnormal placentation is also discussed. ..
  20. Kurtis J, Higashi A, Wu H, Gundogan F, McDonald E, Sharma S, et al. Maternal Schistosomiasis japonica is associated with maternal, placental, and fetal inflammation. Infect Immun. 2011;79:1254-61 pubmed publisher
    ..This potential mechanistic link between maternal schistosomiasis and poor birth outcomes will contribute to the debate regarding treatment of maternal schistosome infections. ..
  21. Mehta N, Larson L. Pharmacotherapy in pregnancy and lactation. Clin Chest Med. 2011;32:43-52 pubmed publisher
    ..This article aims to guide the clinician in choosing the safest and most effective strategy when prescribing medications to patients who are pregnant and breastfeeding. ..
  22. Uzun A, Dewan A, Istrail S, Padbury J. Pathway-based genetic analysis of preterm birth. Genomics. 2013;101:163-70 pubmed publisher
    ..This approach demonstrates the use of a validated set of genes, in the analysis of otherwise unsuccessful GWAS data, to identify gene-gene interactions in a way that enhances statistical power and discovery. ..
  23. Thaxton J, NEVERS T, Lippe E, Blois S, Saito S, Sharma S. NKG2D blockade inhibits poly(I:C)-triggered fetal loss in wild type but not in IL-10-/- mice. J Immunol. 2013;190:3639-47 pubmed publisher
    ..Thus, we demonstrate that pregnancy-disrupting inflammatory events mimicked by poly(I:C) are regulated by IL-10 and depend on the effector function of uterine NKG2D(+) NK cells in WT mice and NKG2D(-) T cells in IL-10 null mice. ..
  24. Michels K, Velez Edwards D, Baird D, Savitz D, Hartmann K. Uterine leiomyomata and cesarean birth risk: a prospective cohort with standardized imaging. Ann Epidemiol. 2014;24:122-6 pubmed publisher
    ..22; CI, 1.14-1.32) and women with the largest total leiomyoma volumes (ARR, 1.59; CI, 1.44-1.76). Women with leiomyomata were at increased risk for cesarean birth particularly, those with larger tumor volumes. ..
  25. Qian Z, Liang S, Yang S, Trevathan E, Huang Z, Yang R, et al. Ambient air pollution and preterm birth: A prospective birth cohort study in Wuhan, China. Int J Hyg Environ Health. 2016;219:195-203 pubmed publisher
    ..Findings reveal an association between air pollutants and PTB. However, more toxicological studies and prospective cohort studies with improved exposure assessments are needed to establish causality related to specific pollutants. ..
  26. Ward N, Hughes B, Mermel L. Enterovirus D68 Infection in an Adult. Am J Crit Care. 2016;25:178-80 pubmed publisher
    ..This case suggests that pregnant women may be a sentinel group infected with this pathogen, similar to what has been described for influenza virus infection. ..
  27. Chen W, Bear M. Activity-dependent regulation of NR2B translation contributes to metaplasticity in mouse visual cortex. Neuropharmacology. 2007;52:200-14 pubmed
    ..Translation of NR2A is not regulated in this manner. Therefore, the differential translational regulation of NR2A and NR2B may contribute to experience-dependent modification of NMDAR subunit composition. ..
  28. Soscia S, Tong M, Xu X, Cohen A, Chu J, Wands J, et al. Chronic gestational exposure to ethanol causes insulin and IGF resistance and impairs acetylcholine homeostasis in the brain. Cell Mol Life Sci. 2006;63:2039-56 pubmed
    ..In conclusion, cerebellar hypoplasia in FAS is mediated by insulin/IGF resistance with attendant impairments in energy production and ACh homeostasis. ..
  29. Duffy C, Allen S. Medical and psychosocial aspects of fertility after cancer. Cancer J. 2009;15:27-33 pubmed publisher
    ..Physician education interventions should seek to improve the knowledge of fertility preservations options, and of locally and nationally available resources. ..
  30. Sharma S, Norris W, Kalkunte S. Beyond the threshold: an etiological bridge between hypoxia and immunity in preeclampsia. J Reprod Immunol. 2010;85:112-6 pubmed publisher
  31. Lagasse L, Derauf C, Smith L, Newman E, Shah R, Neal C, et al. Prenatal methamphetamine exposure and childhood behavior problems at 3 and 5 years of age. Pediatrics. 2012;129:681-8 pubmed publisher
    ..This first report of behavior problems in patients as young as 3 years associated with MA exposure identifies an important public health problem. Continued follow-up can inform the development of preventive intervention programs. ..
  32. Woo H, Phornphutkul C, Laptook A. Early and severe indirect hyperbilirubinemia as a manifestation of galactosemia. J Perinatol. 2010;30:295-7 pubmed publisher
    ..We report an infant with galactosemia who presented with severe jaundice from indirect hyperbilirubinemia and met criteria for an exchange transfusion within 48 h after milk ingestion. ..
  33. Avissar Whiting M, Veiga K, Uhl K, Maccani M, Gagne L, Moen E, et al. Bisphenol A exposure leads to specific microRNA alterations in placental cells. Reprod Toxicol. 2010;29:401-6 pubmed publisher
    ..Overall, these results suggest that BPA can alter miRNA expression in placental cells, a potentially novel mode of BPA toxicity. ..
  34. Gong J, Savitz D, Stein C, Engel S. Maternal ethnicity and pre-eclampsia in New York City, 1995-2003. Paediatr Perinat Epidemiol. 2012;26:45-52 pubmed publisher
    ..Our results should contribute to screening for pre-eclampsia taking ethnic variation into account, and may help to suggest leads for the study of the aetiology of the condition. ..
  35. Bromer C, Marsit C, Armstrong D, Padbury J, Lester B. Genetic and epigenetic variation of the glucocorticoid receptor (NR3C1) in placenta and infant neurobehavior. Dev Psychobiol. 2013;55:673-83 pubmed publisher
    ..Further research is needed to more precisely define these relationships and the interaction between epigenetic alterations and genetic variations on infant health. ..
  36. Sullivan M, Miller R, Fontaine L, Lester B. Refining Neurobehavioral Assessment of the High-Risk Infant Using the NICU Network Neurobehavioral Scale. J Obstet Gynecol Neonatal Nurs. 2012;41:17-23 pubmed publisher
    ..Research evidence supports its validity and reliability for clinical and research use. The NNNS offers nurses a neurobehavioral assessment especially suited to high-risk and premature infants. ..
  37. Demauro S, D Agostino J, Bann C, Bernbaum J, Gerdes M, Bell E, et al. Developmental outcomes of very preterm infants with tracheostomies. J Pediatr. 2014;164:1303-10.e2 pubmed publisher
    ..These data may inform counseling about tracheostomy in this vulnerable population. ..
  38. De Jesus L, Sood B, Shankaran S, Kendrick D, Das A, Bell E, et al. Antenatal magnesium sulfate exposure and acute cardiorespiratory events in preterm infants. Am J Obstet Gynecol. 2015;212:94.e1-7 pubmed publisher
    ..The safety of anteMg as measured by the need for DR intubation or respiratory support on day 1 of life was comparable between groups. ..
  39. Uzun A, Triche E, Schuster J, Dewan A, Padbury J. dbPEC: a comprehensive literature-based database for preeclampsia related genes and phenotypes. Database (Oxford). 2016;2016: pubmed publisher
    ..Database URL: http://ptbdb.cs.brown.edu/dbpec/. ..
  40. Laptook A, Shankaran S, Tyson J, Munoz B, Bell E, Goldberg R, et al. Effect of Therapeutic Hypothermia Initiated After 6 Hours of Age on Death or Disability Among Newborns With Hypoxic-Ischemic Encephalopathy: A Randomized Clinical Trial. JAMA. 2017;318:1550-1560 pubmed publisher
    ..To our knowledge, hypothermia trials have not been performed in infants presenting after 6 hours...
  41. Angelini D. Obstetric triage revisited: update on non-obstetric surgical conditions in pregnancy. J Midwifery Womens Health. 2003;48:111-8 pubmed
    ..Working in obstetric triage settings and triaging obstetric phone calls demand continual updating of abdominal assessment knowledge and clinical skills. ..
  42. Zeanah C, McDonough S. Clinical approaches to families in early intervention. Semin Perinatol. 1989;13:513-22 pubmed
  43. Gruppuso P, Boylan J. Hepatic epidermal growth factor-regulated mitogen-activated protein kinase kinase kinase activity in the rat: lack of identity with known forms of raf and MEKK. FEBS Lett. 2000;466:200-4 pubmed
    ..Our results indicate that hepatic, EGF-sensitive MEK kinase activity may reside with a previously unidentified and physiologically relevant form of Raf and/or MEKK. ..
  44. Lee T, Carpenter M, Heber W, Silver H. Preterm premature rupture of membranes: risks of recurrent complications in the next pregnancy among a population-based sample of gravid women. Am J Obstet Gynecol. 2003;188:209-13 pubmed
    ..Estimates of recurrence risks appear to be moderated by limiting analysis to a population-based sample of gravid women when compared with previous studies. ..
  45. Kalkunte S, Lai Z, Tewari N, Chichester C, Romero R, Padbury J, et al. In vitro and in vivo evidence for lack of endovascular remodeling by third trimester trophoblasts. Placenta. 2008;29:871-8 pubmed publisher
  46. Lester B, Lagasse L. Children of addicted women. J Addict Dis. 2010;29:259-76 pubmed publisher
    ..The author discuss this "fetal origins" approach that involves fetal programming and the neuroendocrine system and the potential implications for adolescent brain and behavioral development. ..
  47. Bourjeily G, Raker C, Chalhoub M, Miller M. Pregnancy and fetal outcomes of symptoms of sleep-disordered breathing. Eur Respir J. 2010;36:849-55 pubmed publisher
    ..Symptoms of SDB are common in pregnancy and associated with a higher likelihood of gestational hypertensive disorders, gestational diabetes and unplanned Caesarean deliveries...
  48. Wadhawan R, Oh W, Hintz S, Blakely M, Das A, Bell E, et al. Neurodevelopmental outcomes of extremely low birth weight infants with spontaneous intestinal perforation or surgical necrotizing enterocolitis. J Perinatol. 2014;34:64-70 pubmed publisher
  49. Gold M, Tzilos G, Stein L, Anderson B, Stein M, Ryan C, et al. A Randomized Controlled Trial to Compare Computer-assisted Motivational Intervention with Didactic Educational Counseling to Reduce Unprotected Sex in Female Adolescents. J Pediatr Adolesc Gynecol. 2016;29:26-32 pubmed publisher
  50. Romano M, Hawley N, Eliot M, Calafat A, Jayatilaka N, Kelsey K, et al. Variability and predictors of urinary concentrations of organophosphate flame retardant metabolites among pregnant women in Rhode Island. Environ Health. 2017;16:40 pubmed publisher
    ..Body size may be an important predictor of urinary flame retardant metabolite concentrations. ..
  51. Weinzweig J, Panter K, Spangenberger A, Harper J, McRae R, Edstrom L. The fetal cleft palate: III. Ultrastructural and functional analysis of palatal development following in utero repair of the congenital model. Plast Reconstr Surg. 2002;109:2355-62 pubmed
    ..Although repaired velar muscle does demonstrate some evidence of ultrastructural change compared with control muscle, these findings are significantly less pronounced than those observed in the unrepaired clefted muscle. ..
  52. Lester B, Tronick E, LaGasse L, Seifer R, Bauer C, Shankaran S, et al. The maternal lifestyle study: effects of substance exposure during pregnancy on neurodevelopmental outcome in 1-month-old infants. Pediatrics. 2002;110:1182-92 pubmed
    ..Long-term follow-up is necessary to determine whether these differences develop into clinically significant deficits. ..
  53. Schmeler K, Mayo Smith W, Peipert J, Weitzen S, Manuel M, Gordinier M. Adnexal masses in pregnancy: surgery compared with observation. Obstet Gynecol. 2005;105:1098-103 pubmed
    ..01). In select cases, close observation is a reasonable alternative to antepartum surgery in patients with an adnexal mass during pregnancy. ..
  54. Miech R. Pathophysiology of mifepristone-induced septic shock due to Clostridium sordellii. Ann Pharmacother. 2005;39:1483-8 pubmed
    ..To explain the role of mifepristone in medical abortions that results in fulminant and lethal septic shock due to Clostridium sordellii...
  55. Buka S, Cannon T, Torrey E, Yolken R. Maternal exposure to herpes simplex virus and risk of psychosis among adult offspring. Biol Psychiatry. 2008;63:809-15 pubmed
    ..These results are consistent with a general model of risk resulting from enhanced maternal immune activation during pregnancy. ..
  56. Gruppuso P, Tsai S, Boylan J, Sanders J. Hepatic translation control in the late-gestation fetal rat. Am J Physiol Regul Integr Comp Physiol. 2008;295:R558-67 pubmed publisher
    ..These differences may confer differential sensitivity to the growth inhibitory effects of rapamycin. ..
  57. Mehter N, Sadowska G, Malaeb S, Stonestreet B. Na+, K+-ATPase activity and subunit isoform protein abundance: effects of antenatal glucocorticoids in the frontal cerebral cortex and renal cortex of ovine fetuses. Reprod Sci. 2009;16:294-307 pubmed publisher
    ..We conclude MC, but not a SC of dexamethasone, affect fetal cerebral and renal Na(+),K(+)-ATPase, and MC result in differential effects on Na(+),K(+)-ATPase in these organs. ..
  58. Wang Y, Maciejewski B, Soto Reyes D, Lee H, Warburton D, Sanchez Esteban J. Mechanical stretch promotes fetal type II epithelial cell differentiation via shedding of HB-EGF and TGF-alpha. J Physiol. 2009;587:1739-53 pubmed publisher
    ..These studies provide novel mechanistic information potentially relevant to fetal lung development and to mechanical ventilation-induced lung injury. ..
  59. Dailey T, Ji H, Long V, Chien E. The role of transforming growth factor beta in cervical remodeling within the rat cervix. Am J Obstet Gynecol. 2009;201:322.e1-6 pubmed publisher
    ..Components of the TGFbeta signaling pathway increase during pregnancy along with Smad2 activation. The decline on day 22 correlates with a transition to the ripening phase supporting a role in cervical remodeling. ..
  60. Lester B, Bagner D, Liu J, Lagasse L, Seifer R, Bauer C, et al. Infant neurobehavioral dysregulation: behavior problems in children with prenatal substance exposure. Pediatrics. 2009;124:1355-62 pubmed publisher
    ..The objective of this study was to test a developmental model of neurobehavioral dysregulation relating prenatal substance exposure to behavior problems at age 7...
  61. Coustan D, Lowe L, Metzger B. The hyperglycemia and adverse pregnancy outcome (HAPO) study: can we use the results as a basis for change?. J Matern Fetal Neonatal Med. 2010;23:204-9 pubmed publisher
    ..Consequently an international group of interested experts is developing recommendations for diagnostic criteria for GDM which, it is hoped, will be adopted world wide. ..
  62. Coustan D, Lowe L, Metzger B, Dyer A. The Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study: paving the way for new diagnostic criteria for gestational diabetes mellitus. Am J Obstet Gynecol. 2010;202:654.e1-6 pubmed publisher
    ..Various authoritative bodies around the world are expected to deliberate the adoption of these criteria...
  63. Ji H, Long V, Briody V, Chien E. Progesterone modulates integrin {alpha}2 (ITGA2) and {alpha}11 (ITGA11) in the pregnant cervix. Reprod Sci. 2011;18:156-63 pubmed publisher
    ..These changes differ among the collagen-binding integrins. Mitogen-activated protein kinase (MAPK) signaling is involved in regulating some of these integrins. ..
  64. Fernbach P, Darlow A, Sloman S. Asymmetries in predictive and diagnostic reasoning. J Exp Psychol Gen. 2011;140:168-85 pubmed publisher
    ..We conclude that people use causal structure to generate probability judgments in a sophisticated but not entirely veridical way. ..
  65. Calmus M, Macksoud E, Tucker R, Iozzo R, Lechner B. A mouse model of spontaneous preterm birth based on the genetic ablation of biglycan and decorin. Reproduction. 2011;142:183-94 pubmed publisher
    ..Thus, the biglycan/decorin null mutant mouse is a model of genetically induced preterm birth and perinatal loss. This model presents novel targets for preventive or therapeutic manipulation of preterm birth. ..
  66. Savitz D. Invited commentary: biomarkers of exposure to drinking water disinfection by-products--are we ready yet?. Am J Epidemiol. 2012;175:276-8 pubmed publisher
    ..In future efforts, investigators need to combine biomarker development with substantive epidemiologic studies to improve on this initial effort and prepare for more definitive research. ..
  67. Spalluto L, Woodfield C, DeBenedectis C, Lazarus E. MR imaging evaluation of abdominal pain during pregnancy: appendicitis and other nonobstetric causes. Radiographics. 2012;32:317-34 pubmed publisher
    ..MR imaging is useful in diagnosing the cause of abdominal pain in a pregnant patient because of its ability to safely demonstrate a wide range of pathologic conditions in the abdomen and pelvis beyond appendicitis...
  68. Caritis S, Venkataramanan R, Thom E, Harper M, Klebanoff M, Sorokin Y, et al. Relationship between 17-alpha hydroxyprogesterone caproate concentration and spontaneous preterm birth. Am J Obstet Gynecol. 2014;210:128.e1-6 pubmed publisher
    ..This finding validates efficacy of this treatment but suggests that additional studies are needed to determine the optimal dosage. ..
  69. Pappas A, Kendrick D, Shankaran S, Stoll B, Bell E, Laptook A, et al. Chorioamnionitis and early childhood outcomes among extremely low-gestational-age neonates. JAMA Pediatr. 2014;168:137-47 pubmed publisher
    ..Antenatal exposure to chorioamnionitis is associated with altered odds of cognitive impairment and death/neurodevelopmental impairment in extremely preterm infants. ..
  70. Nielsen B, Bonney E, Pearce B, Donahue L, Sarkar I. A Cross-Species Analysis of Animal Models for the Investigation of Preterm Birth Mechanisms. Reprod Sci. 2016;23:482-91 pubmed publisher
  71. Allen R, Goldberg A. Cervical dilation before first-trimester surgical abortion (<14 weeks' gestation). Contraception. 2016;93:277-291 pubmed publisher
  72. Oyieng o D, Kirwa K, Tong I, Martin S, Antonio Rojas Suarez J, Bourjeily G. Restless Legs Symptoms and Pregnancy and Neonatal Outcomes. Clin Ther. 2016;38:256-64 pubmed publisher
    ..These findings may affect RLS treatment decisions during pregnancy. ..
  73. He M, Curran P, Raker C, Martin S, Larson L, Bourjeily G. Placental findings associated with maternal obesity at early pregnancy. Pathol Res Pract. 2016;212:282-7 pubmed publisher
    ..Results from the current study suggest that maternal obesity measured at early pregnancy may have effects on both placental implantation and growth, and further exacerbate the hypercoagulable state in placenta. ..
  74. Boylan J, Francois Vaughan H, Gruppuso P, Sanders J. Engraftment and Repopulation Potential of Late Gestation Fetal Rat Hepatocytes. Transplantation. 2017;101:2349-2359 pubmed publisher
    ..This is likely related to the unexpected presence of a significant proportion of hepatocyte marker-positive cells maintaining a less well-differentiated phenotype. ..
  75. Brautigan D, Pinault F. Serine phosphorylation of protein tyrosine phosphatase (PTP1B) in HeLa cells in response to analogues of cAMP or diacylglycerol plus okadaic acid. Mol Cell Biochem. 1993;127-128:121-9 pubmed
    ..Phosphorylation in this region of PTP1B, between the N-terminal catalytic domain and the C-terminal membrane localization segment, is proposed to regulate phosphatase activity. ..
  76. Lee T, Silver H. Etiology and epidemiology of preterm premature rupture of the membranes. Clin Perinatol. 2001;28:721-34 pubmed
    ..These seem to be reasonable and logical interventions to consider in general, and may potentially have an effect on various causal agents of PPROM. ..
  77. Salisbury A, Law K, LaGasse L, Lester B. MSJAMA. Maternal-fetal attachment. JAMA. 2003;289:1701 pubmed
  78. Shenassa E, McCaffery J, Swan G, Khroyan T, Shakib S, Lerman C, et al. Intergenerational transmission of tobacco use and dependence: a transdisciplinary perspective. Nicotine Tob Res. 2003;5 Suppl 1:S55-69 pubmed
    ..Research gaps that exist between scientific disciplines are highlighted, and some directions for future research are suggested. ..
  79. Abellar R, Pepperell J, Greco D, Gundogan F, Kostadinov S, Schwartz J, et al. Effects of chemotherapy during pregnancy on the placenta. Pediatr Dev Pathol. 2009;12:35-41 pubmed publisher
    ..However, without appropriate controls (untreated patients with equivalent malignancies), the specific effects of chemotherapy in this group are difficult to assess. ..
  80. Malaeb S, Hovanesian V, Sarasin M, Hartmann S, Sadowska G, Stonestreet B. Effects of maternal antenatal glucocorticoid treatment on apoptosis in the ovine fetal cerebral cortex. J Neurosci Res. 2009;87:179-89 pubmed publisher
    ..We speculate that a single course of glucocorticoids exerts maturational changes on the rate of apoptosis in the cerebral cortex of preterm ovine fetuses. ..
  81. Kalkunte S, Mselle T, Norris W, Wira C, Sentman C, Sharma S. Vascular endothelial growth factor C facilitates immune tolerance and endovascular activity of human uterine NK cells at the maternal-fetal interface. J Immunol. 2009;182:4085-92 pubmed publisher
    ..Overall, these results demonstrate that empowerment of uNK cells with angiogenic factors keeps them noncytotoxic. This phenotype is critical to their pregnancy-compatible immunovascular role during placentation and fetal development. ..
  82. Sadowska G, Malaeb S, Stonestreet B. Maternal glucocorticoid exposure alters tight junction protein expression in the brain of fetal sheep. Am J Physiol Heart Circ Physiol. 2010;298:H179-88 pubmed publisher
    ..In utero glucocorticoid exposure alters the molecular composition of the barrier and affects fetal blood-brain barrier function. ..
  83. Pinar H, Carpenter M. Placenta and umbilical cord abnormalities seen with stillbirth. Clin Obstet Gynecol. 2010;53:656-72 pubmed publisher
    ..Second, we provide a brief organization of histological findings of the pathogenesis of conditions associated with fetal death. ..
  84. GALARRAGA O, Wirtz V, Figueroa Lara A, Santa Ana Téllez Y, Coulibaly I, Viisainen K, et al. Unit costs for delivery of antiretroviral treatment and prevention of mother-to-child transmission of HIV: a systematic review for low- and middle-income countries. Pharmacoeconomics. 2011;29:579-99 pubmed publisher
    ..Future work should help elucidate the sources of the large variations in delivery unit costs across settings with similar income and epidemiological characteristics. ..
  85. Gundogan F, Bedoya A, Gilligan J, Lau E, Mark P, De Paepe M, et al. siRNA inhibition of aspartyl-asparaginyl ?-hydroxylase expression impairs cell motility, Notch signaling, and fetal growth. Pathol Res Pract. 2011;207:545-53 pubmed publisher
  86. Salisbury A, Wisner K, Pearlstein T, Battle C, Stroud L, Lester B. Newborn neurobehavioral patterns are differentially related to prenatal maternal major depressive disorder and serotonin reuptake inhibitor treatment. Depress Anxiety. 2011;28:1008-19 pubmed publisher
    ..MDD + SRI-exposed infants seem to have a different neurobehavioral profile than MDD-exposed infants in the first 3 weeks after delivery; both groups may have different neurobehavioral profiles with increasing age from birth. ..
  87. King E, Shih G, Ratnapradipa D, Quilliam D, Morton J, Magee S. Mercury, lead, and cadmium in umbilical cord blood. J Environ Health. 2013;75:38-43 pubmed
    ..6 times more likely to have a mercury concentration > or = 5.8 microg/L compared to women of other racial/ethnic backgrounds. No association was detected between elevated mercury levels and adverse birth outcomes. ..
  88. Allswede D, Buka S, Yolken R, Torrey E, Cannon T. Elevated maternal cytokine levels at birth and risk for psychosis in adult offspring. Schizophr Res. 2016;172:41-5 pubmed publisher
    ..These results may suggest that increased maternal levels of anti-inflammatory cytokines during the perinatal period could protect against the development of psychosis. ..
  89. Kay A, Nishimwe A, Hampton B. Giving Voice to the Experiences of Rwandan Women With Urogenital Fistula. Ann Glob Health. 2015;81:636-44 pubmed publisher
    ..Through patients' narratives, physicians can improve their appreciation of cultural differences to design targeted educational and preventive interventions. ..
  90. Wing D, Ortega Villa A, Grobman W, Hediger M, Grewal J, Pugh S, et al. Maternal stress and neonatal anthropometry: the NICHD Fetal Growth Studies. Am J Obstet Gynecol. 2017;217:82.e1-82.e7 pubmed publisher
    ..There was no effect modification by maternal race/ethnicity. Neonatal measurements did not differ by levels of perceived stress among low-risk pregnant women. ..
  91. Stonestreet B, Petersson K, Sadowska G, Patlak C. Regulation of brain water during acute glucose-induced hyperosmolality in ovine fetuses, lambs, and adults. J Appl Physiol (1985). 2004;96:553-60 pubmed
  92. Murphy M, Ayazifar M. Permanent visual deficits secondary to the HELLP syndrome. J Neuroophthalmol. 2005;25:122-7 pubmed
    ..The superimposition of the HELLP syndrome may create more neurologic damage. Clinicians should be alert to patients at risk for HELLP syndrome and manage them aggressively. ..