Experts and Doctors on membrane fusion in Pittsburgh, Pennsylvania, United States

Summary

Locale: Pittsburgh, Pennsylvania, United States
Topic: membrane fusion

Top Publications

  1. Vernon R, Chong P, Lin H, Yang Z, Zhou Q, Aleksandrov A, et al. Stabilization of a nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator yields insight into disease-causing mutations. J Biol Chem. 2017;292:14147-14164 pubmed publisher
  2. Puthenveedu M, Bachert C, Puri S, Lanni F, Linstedt A. GM130 and GRASP65-dependent lateral cisternal fusion allows uniform Golgi-enzyme distribution. Nat Cell Biol. 2006;8:238-48 pubmed
    ..The membrane continuity created by ribbon formation facilitates optimal processing conditions in the biosynthetic pathway. ..
  3. Tristram Nagle S, Chan R, Kooijman E, Uppamoochikkal P, Qiang W, Weliky D, et al. HIV fusion peptide penetrates, disorders, and softens T-cell membrane mimics. J Mol Biol. 2010;402:139-53 pubmed publisher
    ..Our results are consistent with the HIV FP disordering and softening the T-cell membrane, thereby lowering the activation energy for viral membrane fusion. ..
  4. Yu Y, Lee H, Chen K, Suhan J, Qiu M, Ba Q, et al. Inner membrane fusion mediates spatial distribution of axonal mitochondria. Sci Rep. 2016;6:18981 pubmed publisher
  5. Linstedt A, Jesch S, Mehta A, Lee T, Garcia Mata R, Nelson D, et al. Binding relationships of membrane tethering components. The giantin N terminus and the GM130 N terminus compete for binding to the p115 C terminus. J Biol Chem. 2000;275:10196-201 pubmed
    ..These results question a simple tethering model involving a ternary giantin-p115-GM130 complex and suggest that p115-giantin and p115-GM130 interactions might mediate independent membrane tethering events. ..
  6. Jankowski R, Deasy B, Cao B, Gates C, Huard J. The role of CD34 expression and cellular fusion in the regeneration capacity of myogenic progenitor cells. J Cell Sci. 2002;115:4361-74 pubmed
  7. Morin Leisk J, Saini S, Meng X, Makhov A, Zhang P, Lee T. An intramolecular salt bridge drives the soluble domain of GTP-bound atlastin into the postfusion conformation. J Cell Biol. 2011;195:605-15 pubmed publisher