Experts and Doctors on fontan procedure in Philadelphia, Pennsylvania, United States
Locale: Philadelphia, Pennsylvania, United States
Topic: fontan procedure
Paridon S, Mitchell P, Colan S, Williams R, Blaufox A, Li J, et al
. A cross-sectional study of exercise performance during the first 2 decades of life after the Fontan operation. J Am Coll Cardiol. 2008;52:99-107 pubmed publisher
..Higher O(2) pulse is associated with better exercise performance, whereas adolescence and male gender are associated with decreased performance compared with healthy subjects. ..
Allen K, Downing T, Glatz A, Rogers L, Ravishankar C, Rychik J, et al
. Effect of Fontan-Associated Morbidities on Survival With Intact Fontan Circulation. Am J Cardiol. 2017;119:1866-1871 pubmed publisher
..However, for those patients who remain free from the composite morbidity outcome, 20-year survival with intact Fontan circulation is encouraging. ..
Petko M, Myung R, Wernovsky G, Cohen M, Rychik J, Nicolson S, et al
. Surgical reinterventions following the Fontan procedure. Eur J Cardiothorac Surg. 2003;24:255-9 pubmed
..Most reinterventions can be performed with minimal morbidity and mortality. Survival for patients requiring cardiac transplantation following the Fontan procedure remains poor. ..
Goldberg D, Dodds K, Rychik J. Rare problems associated with the Fontan circulation. Cardiol Young. 2010;20 Suppl 3:113-9 pubmed publisher
..Continued collaboration between sub-specialists and between institutions will be required to optimise the care for this group of survivors with functionally univentricular hearts. ..
Goldberg D, French B, McBride M, Marino B, Mirarchi N, Hanna B, et al
. Impact of oral sildenafil on exercise performance in children and young adults after the fontan operation: a randomized, double-blind, placebo-controlled, crossover trial. Circulation. 2011;123:1185-93 pubmed publisher
..Clinical Trial Registration- URL: http://clinicaltrials.gov. Unique identifier: NCT00507819. ..
Goldberg D, Paridon S. Fontan circulation: the search for targeted therapy. Circulation. 2014;130:1999-2001 pubmed publisher
Atz A, Zak V, Mahony L, Uzark K, D agincourt N, Goldberg D, et al
. Longitudinal Outcomes of Patients With Single Ventricle After the Fontan Procedure. J Am Coll Cardiol. 2017;69:2735-2744 pubmed publisher
..Future interventions might focus on preserving exercise capacity. (Relationship Between Functional Health Status and Ventricular Performance After Fontan-Pediatric Heart Network; NCT00132782). ..
Goldberg D, Zak V, Goldstein B, Chen S, Hamstra M, Radojewski E, et al
. Results of a phase I/II multi-center investigation of udenafil in adolescents after fontan palliation. Am Heart J. 2017;188:42-52 pubmed publisher
..These data suggest that the 87.5 mg bid regimen may be the most appropriate for a Phase III clinical trial. ..