Experts and Doctors on xenopus proteins in Chapel Hill, North Carolina, United States


Locale: Chapel Hill, North Carolina, United States
Topic: xenopus proteins

Top Publications

  1. Sullivan E, Santiago C, Parker E, Dominski Z, Yang X, Lanzotti D, et al. Drosophila stem loop binding protein coordinates accumulation of mature histone mRNA with cell cycle progression. Genes Dev. 2001;15:173-87 pubmed
    ..Moreover, dSLBP-dependent processing plays an important role in coupling histone mRNA production with the cell cycle. ..
  2. Dominski Z, Erkmann J, Greenland J, Marzluff W. Mutations in the RNA binding domain of stem-loop binding protein define separable requirements for RNA binding and for histone pre-mRNA processing. Mol Cell Biol. 2001;21:2008-17 pubmed
    ..It is likely that the RBD of SLBP interacts directly with both the stem-loop RNA and other processing factor(s), most likely the U7 snRNP, to facilitate histone pre-mRNA processing. ..
  3. Moser M, Binder O, Wu Y, Aitsebaomo J, Ren R, Bode C, et al. BMPER, a novel endothelial cell precursor-derived protein, antagonizes bone morphogenetic protein signaling and endothelial cell differentiation. Mol Cell Biol. 2003;23:5664-79 pubmed
  4. Showell C, Binder O, Conlon F. T-box genes in early embryogenesis. Dev Dyn. 2004;229:201-18 pubmed
    ..Developmental Dynamics 229:201-218, 2004. ..
  5. Goetz S, Brown D, Conlon F. TBX5 is required for embryonic cardiac cell cycle progression. Development. 2006;133:2575-84 pubmed publisher
    ..Thus, these studies establish a role for TBX5 in regulating the progression of the cardiac cell cycle...
  6. Mangiamele L, Thomson C, Lebonville C, Burmeister S. Characterization of the plasticity-related gene, Arc, in the frog brain. Dev Neurobiol. 2010;70:813-25 pubmed publisher
  7. Wang Z, Ingledue T, Dominski Z, Sanchez R, Marzluff W. Two Xenopus proteins that bind the 3' end of histone mRNA: implications for translational control of histone synthesis during oogenesis. Mol Cell Biol. 1999;19:835-45 pubmed
    ..As oocytes mature, SLBP2 is degraded and a larger fraction of the histone mRNA is bound to SLBP1. The mechanism of activation of translation of histone mRNAs may involve exchange of SLBPs associated with the 3' end of histone mRNA. ..
  8. Maynard T, Jain M, Balmer C, LaMantia A. High-resolution mapping of the Gli3 mutation extra-toes reveals a 51.5-kb deletion. Mamm Genome. 2002;13:58-61 pubmed
  9. Dominski Z, Erkmann J, Yang X, Sanchez R, Marzluff W. A novel zinc finger protein is associated with U7 snRNP and interacts with the stem-loop binding protein in the histone pre-mRNP to stimulate 3'-end processing. Genes Dev. 2002;16:58-71 pubmed
    ..Antibodies to hZFP100 precipitate U7 snRNA, and expression of hZFP100 in Xenopus oocytes stimulates processing of histone pre-mRNA, showing that hZFP100 is a component of the processing machinery. ..

More Information


  1. Zheng L, Dominski Z, Yang X, Elms P, Raska C, Borchers C, et al. Phosphorylation of stem-loop binding protein (SLBP) on two threonines triggers degradation of SLBP, the sole cell cycle-regulated factor required for regulation of histone mRNA processing, at the end of S phase. Mol Cell Biol. 2003;23:1590-601 pubmed
  2. Sar F, Lindsey Boltz L, Subramanian D, Croteau D, Hutsell S, Griffith J, et al. Human claspin is a ring-shaped DNA-binding protein with high affinity to branched DNA structures. J Biol Chem. 2004;279:39289-95 pubmed
  3. Christine K, Conlon F. Vertebrate CASTOR is required for differentiation of cardiac precursor cells at the ventral midline. Dev Cell. 2008;14:616-23 pubmed publisher
    ..These midline-specific requirements for CST suggest the regulation of cardiomyocyte differentiation is regionalized along a dorsal-ventral axis and that this patterning occurs prior to heart tube formation...
  4. Garcia Caballero A, Rasmussen J, Gaillard E, Watson M, Olsen J, Donaldson S, et al. SPLUNC1 regulates airway surface liquid volume by protecting ENaC from proteolytic cleavage. Proc Natl Acad Sci U S A. 2009;106:11412-7 pubmed publisher
    ..Thus, we propose that SPLUNC1 is secreted onto mucosal surfaces as a soluble volume sensor whose concentration and dilution can regulate ENaC activity and mucosal volumes, including that of airway surface liquid. ..
  5. Gee S, Milgram S, Kramer K, Conlon F, Moody S. Yes-associated protein 65 (YAP) expands neural progenitors and regulates Pax3 expression in the neural plate border zone. PLoS ONE. 2011;6:e20309 pubmed publisher
  6. Tandon P, Miteva Y, Kuchenbrod L, Cristea I, Conlon F. Tcf21 regulates the specification and maturation of proepicardial cells. Development. 2013;140:2409-21 pubmed publisher
    ..Collectively, these studies lead us to propose that Tcf21 functions as a transcriptional repressor to regulate proepicardial cell specification and the correct formation of a mature epithelial epicardium. ..