Experts and Doctors on middle aged in Durham, North Carolina, United States


Locale: Durham, North Carolina, United States
Topic: middle aged

Top Publications

  1. Barber M, Kuchibhatla M, Pieper C, Bump R. Psychometric evaluation of 2 comprehensive condition-specific quality of life instruments for women with pelvic floor disorders. Am J Obstet Gynecol. 2001;185:1388-95 pubmed
    ..29, P <.01). The total time taken to complete both instruments averaged 23 minutes (range, 9-55). The PFDI and the PFIQ are reliable, valid, condition-specific quality of life instruments for women with pelvic floor disorders. ..
  2. Brummett B, Krystal A, Siegler I, Kuhn C, Surwit R, Zuchner S, et al. Associations of a regulatory polymorphism of monoamine oxidase-A gene promoter (MAOA-uVNTR) with symptoms of depression and sleep quality. Psychosom Med. 2007;69:396-401 pubmed
    ..04; Cohen's d = 0.52) and poorer sleep quality (p < .04; Cohen's d = 0.31). Individuals with less active MAOA-uVNTR alleles may be at increased risk for depressive symptoms and poor sleep. ..
  3. Gadkowski L, Hamilton C, Allen M, Fortenberry E, Luffman J, Zeringue E, et al. HIV-specific health care utilization and mortality among tuberculosis/HIV coinfected persons. AIDS Patient Care STDS. 2009;23:845-51 pubmed publisher
    ..Interventions to enhance utilization of HIV-related health care and integration of TB and HIV services should be studied to improve outcomes. ..
  4. Ehlers J, Decroos F, Fekrat S. Intravitreal bevacizumab for macular edema secondary to branch retinal vein occlusion. Retina. 2011;31:1856-62 pubmed publisher
    ..To evaluate the effect of intravitreal bevacizumab on the visual and anatomical outcome in eyes with macular edema secondary to branch retinal vein occlusion...
  5. Hutchinson C, Stoecker M, Wang F, Papalas J, Sebastian S, Burchette J, et al. Molecular detection of circulating Sezary cells in patients with mycosis fungoides: could it predict future development of secondary Sezary syndrome? A single-institution experience. Leuk Lymphoma. 2012;53:868-77 pubmed publisher
    ..Due to amplification of non-neoplastic T-cell expansion in a significant number of cases, comparison of blood T-cell clones with skin may have confirmatory value. ..
  6. Previs R, Bevis K, Huh W, Tillmanns T, Perry L, Moore K, et al. A prognostic nomogram to predict overall survival in women with recurrent ovarian cancer treated with bevacizumab and chemotherapy. Gynecol Oncol. 2014;132:531-6 pubmed publisher
    ..Our nomogram to predict five-year OS may be used to identify women who may benefit from bevacizumab and chemotherapy, but further validation is needed. ..
  7. Youngwirth L, Adam M, Scheri R, Roman S, Sosa J. Patients Treated at Low-Volume Centers have Higher Rates of Incomplete Resection and Compromised Outcomes: Analysis of 31,129 Patients with Papillary Thyroid Cancer. Ann Surg Oncol. 2016;23:403-9 pubmed publisher
    ..Several vulnerable patient populations have a higher risk of incomplete resection after thyroidectomy for PTC. High-risk thyroid cancer patients should be referred to high-volume centers to optimize outcomes. ..
  8. Lipscomb H, Dement J, Nolan J, Patterson D, Li L. Nail gun injuries in residential carpentry: lessons from active injury surveillance. Inj Prev. 2003;9:20-4 pubmed
  9. Lipscomb H, Loomis D, McDonald M, Kucera K, Marshall S, Li L. Musculoskeletal symptoms among commercial fishers in North Carolina. Appl Ergon. 2004;35:417-26 pubmed
    ..Reducing ergonomic exposures associated with work among these traditional workers is important, regardless of whether they directly cause or contribute to their musculoskeletal symptoms, or aggravate existing pathology. ..

More Information

Publications675 found, 100 shown here

  1. Olsen E, Messenger A, Shapiro J, Bergfeld W, Hordinsky M, Roberts J, et al. Evaluation and treatment of male and female pattern hair loss. J Am Acad Dermatol. 2005;52:301-11 pubmed
  2. Chieh J, Carlson A, Jaffe G. Combined fluocinolone acetonide intraocular delivery system insertion, phacoemulsification, and intraocular lens implantation for severe uveitis. Am J Ophthalmol. 2008;146:589-594 pubmed publisher
    ..VA generally was improved, uveitis recurrences decreased, and the need for immunosuppression decreased. The most common side effect was increased IOP. ..
  3. Erdmann D, Bruno A, Follmar K, Stokes T, Gonyon D, Marcus J. The helical arcade: anatomic basis for survival in near-total ear avulsion. J Craniofac Surg. 2009;20:245-8 pubmed publisher
    ..This arcade seems to allow for communication between the anterior and posterior arterial systems of the ear and allows the helical artery to provide sufficient arterial supply to the entire ear...
  4. Rao A, Valk P, Metzeler K, Acharya C, Tuchman S, Stevenson M, et al. Age-specific differences in oncogenic pathway dysregulation and anthracycline sensitivity in patients with acute myeloid leukemia. J Clin Oncol. 2009;27:5580-6 pubmed publisher
    ..These insights should enable development and adjustments of clinically meaningful treatment strategies in the older patient population. ..
  5. Ulmer C, Edinger J, Calhoun P. A multi-component cognitive-behavioral intervention for sleep disturbance in veterans with PTSD: a pilot study. J Clin Sleep Med. 2011;7:57-68 pubmed
    ..A combined intervention involving both a nightmare-specific intervention and CBT for insomnia may lead to more marked reductions in PTSD-related sleep disturbances...
  6. Guyton J, Betteridge D, Farnier M, Leiter L, Lin J, Shah A, et al. Achievement of recommended lipid and lipoprotein levels with combined ezetimibe/statin therapy versus statin alone in patients with and without diabetes. Diab Vasc Dis Res. 2011;8:160-72 pubmed publisher
    ..Patients with diabetes benefitted at least as much as, and sometimes more than, non-diabetes patients following treatment with ezetimibe/statin. ..
  7. Beaven A, Shea T, Moore D, Feldman T, Ivanova A, Ferraro M, et al. A phase I study evaluating ibritumomab tiuxetan (Zevalin®) in combination with bortezomib (Velcade®) in relapsed/refractory mantle cell and low grade B-cell non-Hodgkin lymphoma. Leuk Lymphoma. 2012;53:254-8 pubmed publisher
    ..3%) for an overall response rate (ORR) of 50%. The combination of standard dose ibritumomab tiuxetan and bortezomib at 1.5 mg/m(2) is well tolerated with a promising response rate. ..
  8. Muse K, Lukes A, Gersten J, Waldbaum A, Mabey R, Trott E. Long-term evaluation of safety and health-related quality of life in women with heavy menstrual bleeding treated with oral tranexamic acid. Womens Health (Lond). 2011;7:699-707 pubmed publisher
    ..Long-term TA treatment was well tolerated and improved measures of HRQoL in women with cyclic HMB. ..
  9. Jollis J, Al Khalidi H, Monk L, Roettig M, Garvey J, Aluko A, et al. Expansion of a regional ST-segment-elevation myocardial infarction system to an entire state. Circulation. 2012;126:189-95 pubmed publisher
  10. Urban T, Shen Y, Stolz A, Chalasani N, Fontana R, Rochon J, et al. Limited contribution of common genetic variants to risk for liver injury due to a variety of drugs. Pharmacogenet Genomics. 2012;22:784-95 pubmed publisher
    ..However, the lack of genome-wide association study findings supports the idea that strong genetic determinants of DILI may be largely drug-specific or may reflect rare genetic variations, which were not assessed in our study. ..
  11. Weigt S, Copeland C, DerHovanessian A, Shino M, Davis W, Snyder L, et al. Colonization with small conidia Aspergillus species is associated with bronchiolitis obliterans syndrome: a two-center validation study. Am J Transplant. 2013;13:919-927 pubmed publisher
    ..Prospective evaluation of strategies to prevent Aspergillus colonization of small airways is warranted, with the goal of preserving lung allograft function as long as possible...
  12. Vavalle J, Clare R, Chiswell K, Rao S, Petersen J, Kleiman N, et al. Prognostic significance of bleeding location and severity among patients with acute coronary syndromes. JACC Cardiovasc Interv. 2013;6:709-17 pubmed publisher
    ..These data underscore the importance of strategies to minimize overall bleeding risk beyond vascular access site management. ..
  13. Kelsey C, Christensen J, Chino J, Adamson J, Ready N, Perez B. Adaptive planning using positron emission tomography for locally advanced lung cancer: A feasibility study. Pract Radiat Oncol. 2016;6:96-104 pubmed publisher
    ..01). Adaptive planning using PET-CT was feasible and allows for significant dose reductions to normal tissues compared with traditional planning techniques. ..
  14. Piccolo S, Hoffman L, Conner T, Shrestha G, Cohen A, Marks J, et al. Integrative analyses reveal signaling pathways underlying familial breast cancer susceptibility. Mol Syst Biol. 2016;12:860 pubmed publisher
  15. Pritchett E, Page R, Connolly S, Marcello S, Schnell D, Wilkinson W. Antiarrhythmic effects of azimilide in atrial fibrillation: efficacy and dose-response. Azimilide Supraventricular Arrhythmia Program 3 (SVA-3) Investigators. J Am Coll Cardiol. 2000;36:794-802 pubmed
    ..08), and for the 125 mg group, dose was 1.83 (95% CI = 1.24, 2.70; p = 0.002). Azimilide significantly lengthened the symptomatic arrhythmia-free interval in patients with a history of atrial fibrillation, atrial flutter or both. ..
  16. Creager A, Pitman M, Geisinger K. Cytologic features of clear cell sarcoma (malignant melanoma) of soft parts: a study of fine-needle aspirates and exfoliative specimens. Am J Clin Pathol. 2002;117:217-24 pubmed
    ..Owing to the rarity of CCS, the diagnosis on cytologic smears is extremely difficult and is aided substantially by pertinent clinical data. The diagnosis can be made conclusively by..
  17. Hagen S, Kondyra A, Grocott H, El Moalem H, Bainbridge D, Mathew J, et al. Cardiopulmonary bypass decreases G protein-coupled receptor kinase activity and expression in human peripheral blood mononuclear cells. Anesthesiology. 2003;98:343-8 pubmed
    ..The significance of the variable recovery of GRKs after CPB and their potential role as a marker of clinical outcome deserves further investigation. ..
  18. Mohamed H, Nair P. One-stop clinic for postmenopausal bleeding at district general hospital: does it have a role?. J Obstet Gynaecol. 2003;23:182-4 pubmed
    ..This study demonstrates the effective role of the one-stop PMB clinic to provide quick reassurance, arrive at a diagnosis and initiate plan of management during a single outpatient visit. ..
  19. Mohler P, Splawski I, Napolitano C, Bottelli G, Sharpe L, Timothy K, et al. A cardiac arrhythmia syndrome caused by loss of ankyrin-B function. Proc Natl Acad Sci U S A. 2004;101:9137-42 pubmed
  20. Habib A, Gan T. The effectiveness of rescue antiemetics after failure of prophylaxis with ondansetron or droperidol: a preliminary report. J Clin Anesth. 2005;17:62-5 pubmed
    ..To compare the effectiveness of treating established postoperative nausea and vomiting (PONV) with an antiemetic acting at a different receptor with that of treating PONV with the antiemetic used for prophylaxis...
  21. Mitchell R, Duscha B, Robbins J, Redfern S, Chung J, Bensimhon D, et al. Increased levels of apoptosis in gastrocnemius skeletal muscle in patients with peripheral arterial disease. Vasc Med. 2007;12:285-90 pubmed
    ..53% +/- 0.96; p < 0.001). In conclusion, PAD is associated with increased levels of apoptosis in the peripheral skeletal muscle. Further study is required to ascertain whether apoptosis plays a role in decreased functional capacity. ..
  22. Chen V, Mayes J, Madden J, Stein A, Mouraviev V, Polascik T. The effect of cryoablation on the histologic interpretation of intraoperative biopsy of small clear cell renal carcinoma and renal oncocytoma. J Endourol. 2008;22:1617-21 pubmed publisher
    ..One cycle of cryoablation does not significantly alter the architecture or Fuhrman grade of biopsy tissue, thus allowing for another method to obtain sufficient histologic tissue when bleeding is minimal. ..
  23. Naggie S, Frederick J, Pien B, Miller B, Provenzale D, Goldberg K, et al. Community-associated Clostridium difficile infection: experience of a veteran affairs medical center in southeastern USA. Infection. 2010;38:297-300 pubmed publisher
    ..Compared to patients with HCFA-CDI, those with CA-CDI were younger, had fewer reported exposures to antimicrobials or PPIs, and had lower mortality. Further study is needed to identify unrecognized risk factors of CDI in the community. ..
  24. Miles A, Proescholdbell R, Puffer E. Explaining rural/non-rural disparities in physical health-related quality of life: a study of United Methodist clergy in North Carolina. Qual Life Res. 2011;20:807-15 pubmed publisher
    ..More research into the causes and prevention of these factors is needed. Researchers also should seek to identify variables that can explain the difference that remains after accounting for these variables. ..
  25. Al Khatib S, Hellkamp A, Curtis J, Mark D, Peterson E, Sanders G, et al. Non-evidence-based ICD implantations in the United States. JAMA. 2011;305:43-9 pubmed publisher
    ..7% [3597/16,549] in 2009; P <.001 for trend from 2006-2009 and P = .94 for trend from 2007-2009). Among patients with ICD implants in this registry, 22.5% did not meet evidence-based criteria for implantation. ..
  26. Haga S, O Daniel J, Tindall G, Lipkus I, Agans R. Survey of US public attitudes toward pharmacogenetic testing. Pharmacogenomics J. 2012;12:197-204 pubmed publisher
    ..Given differences in interest among some groups, providers should clearly discuss the purpose of testing, alternative testing options (if available) and policies to protect patient privacy and confidentiality. ..
  27. Driehuys B, Martinez Jimenez S, Cleveland Z, Metz G, Beaver D, Nouls J, et al. Chronic obstructive pulmonary disease: safety and tolerability of hyperpolarized 129Xe MR imaging in healthy volunteers and patients. Radiology. 2012;262:279-89 pubmed publisher
    ..To evaluate the safety and tolerability of inhaling multiple 1-L volumes of undiluted hyperpolarized xenon 129 ((129)Xe) followed by up to a 16-second breath hold and magnetic resonance (MR) imaging...
  28. Sampson J, Schmittling R, Archer G, Congdon K, Nair S, Reap E, et al. A pilot study of IL-2R? blockade during lymphopenia depletes regulatory T-cells and correlates with enhanced immunity in patients with glioblastoma. PLoS ONE. 2012;7:e31046 pubmed publisher
    ..These data suggest this approach deserves further study. NCT00626015. ..
  29. Dalal A, Shah M, D Souza A, Lunacsek O, Nagar S, Crater G. Observational study of the outcomes and costs of initiating maintenance therapies in patients with moderate exacerbations of COPD. Respir Res. 2012;13:41 pubmed publisher
    ..Only a quarter of patients with a moderate COPD exacerbation were subsequently treated with maintenance therapy. Initiation of FSC among those treated was associated with better clinical and economic outcomes compared to AC. ..
  30. Haga S, Barry W, Mills R, Ginsburg G, Svetkey L, Sullivan J, et al. Public knowledge of and attitudes toward genetics and genetic testing. Genet Test Mol Biomarkers. 2013;17:327-35 pubmed publisher
  31. Michelson D, Snyder E, Paradis E, Chengan Liu M, Snavely D, Hutzelmann J, et al. Safety and efficacy of suvorexant during 1-year treatment of insomnia with subsequent abrupt treatment discontinuation: a phase 3 randomised, double-blind, placebo-controlled trial. Lancet Neurol. 2014;13:461-71 pubmed publisher
    ..Our findings show that suvorexant was generally safe and well tolerated over 1 year of nightly treatment in patients with insomnia, with efficacy noted for subjective measures of sleep onset and maintenance. Merck & Co Inc. ..
  32. Haley D, Lucas J, Golin C, Wang J, Hughes J, Emel L, et al. Retention strategies and factors associated with missed visits among low income women at increased risk of HIV acquisition in the US (HPTN 064). AIDS Patient Care STDS. 2014;28:206-17 pubmed publisher
    ..Multifaceted retention strategies may reduce missed study visits. Knowledge of factors associated with missed visits may help to focus efforts. ..
  33. Fu Q, Zhu Y, Ren Q. The downside of marketization: a multilevel analysis of housing tenure and types in reform-era urban China. Soc Sci Res. 2015;49:126-40 pubmed publisher
  34. Haws K, Liu P. Half-size me? How calorie and price information influence ordering on restaurant menus with both half and full entrée portion sizes. Appetite. 2016;97:127-37 pubmed publisher
  35. Qin B, Moorman P, Alberg A, Barnholtz Sloan J, Bondy M, Cote M, et al. Dietary carbohydrate intake, glycaemic load, glycaemic index and ovarian cancer risk in African-American women. Br J Nutr. 2016;115:694-702 pubmed publisher
    ..No associations were observed for starch or GI. Our findings suggest that high intake of total sugars and GL are associated with greater risk of ovarian cancer in African-American women. ..
  36. Raslan I, Brown P, Westerhout C, Ezekowitz J, Hernandez A, Starling R, et al. Characterization of hemodynamically stable acute heart failure patients requiring a critical care unit admission: Derivation, validation, and refinement of a risk score. Am Heart J. 2017;188:127-135 pubmed publisher
    ..The model has modest discrimination; however, these findings deserve further exploration because they may provide a more accurate means of triaging level of care for patients with AHF who need admission. ..
  37. Schadendorf D, Larkin J, Wolchok J, Hodi F, Chiarion Sileni V, Gonzalez R, et al. Health-related quality of life results from the phase III CheckMate 067 study. Eur J Cancer. 2017;82:80-91 pubmed publisher
    ..The finding that the difference in grade 3/4 AEs between the arms did not translate into clinically meaningful differences in the reported HRQoL may be relevant in the clinical setting. NCT01844505. ..
  38. Smith A, Bai D, Marroquin C, Tuttle Newhall J, Desai D, Collins B, et al. Gastrointestinal hemorrhage due to complicated gastroduodenal ulcer disease in liver transplant patients taking sirolimus. Clin Transplant. 2005;19:250-4 pubmed
  39. Madden J, Burchette J, Raj G, Daly J, Tannenbaum M. Anterior rectal wall gastrointestinal stromal tumor presenting clinically as prostatic mass. Urol Oncol. 2005;23:268-72 pubmed
    ..Additional therapy with imatinib (Gleevec, Novartis Pharmaceuticals Corporation, East Hanover, NJ), an inhibitor of CD117 tyrosine kinase activity, treated recurrence in one patient and effected complete remission. ..
  40. Gan T, Coop A, Philip B. A randomized, double-blind study of granisetron plus dexamethasone versus ondansetron plus dexamethasone to prevent postoperative nausea and vomiting in patients undergoing abdominal hysterectomy. Anesth Analg. 2005;101:1323-9 pubmed
    ..The combination of small-dose G administered just before tracheal extubation plus D given at induction of anesthesia is an effective alternative to O+D in preventing vomiting during the 0- to 2-h interval after tracheal extubation. ..
  41. Schiffman S, Sattely Miller E, Taylor E, Graham B, Landerman L, Zervakis J, et al. Combination of flavor enhancement and chemosensory education improves nutritional status in older cancer patients. J Nutr Health Aging. 2007;11:439-54 pubmed
  42. Chu V, Woods C, Miro J, Hoen B, Cabell C, Pappas P, et al. Emergence of coagulase-negative staphylococci as a cause of native valve endocarditis. Clin Infect Dis. 2008;46:232-42 pubmed publisher
    ..Coagulase-negative staphylococci (CoNS) are an infrequent cause of native valve endocarditis (NVE), and our understanding of NVE caused by CoNS is incomplete...
  43. Hobson Webb L, Padua L. Median nerve ultrasonography in carpal tunnel syndrome: findings from two laboratories. Muscle Nerve. 2009;40:94-7 pubmed publisher
    ..Median nerve US is less susceptible to differences between laboratories than previously thought, permitting greater generalization of findings. ..
  44. Al Khatib S, Hafley G, Lee K, Buxton A. Relation between time from myocardial infarction to enrolment and patient outcomes in the Multicenter UnSustained Tachycardia Trial. Europace. 2010;12:1112-8 pubmed publisher
    ..Although ICD therapy was associated with improved survival regardless of the time from MI to enrolment, this finding needs to be verified by a randomized clinical trial. ..
  45. Palmer S, Limaye A, Banks M, Gallup D, Chapman J, Lawrence E, et al. Extended valganciclovir prophylaxis to prevent cytomegalovirus after lung transplantation: a randomized, controlled trial. Ann Intern Med. 2010;152:761-9 pubmed publisher
    ..A beneficial effect with regard to prevention of CMV disease seems to extend at least through 18 months after transplantation. ..
  46. Ready N, Karaseva N, Orlov S, Luft A, Popovych O, Holmlund J, et al. Double-blind, placebo-controlled, randomized phase 2 study of the proapoptotic agent AT-101 plus docetaxel, in second-line non-small cell lung cancer. J Thorac Oncol. 2011;6:781-5 pubmed publisher
    ..AT-101 plus docetaxel was well tolerated with an adverse event profile indistinguishable from the base docetaxel regimen. AT-101 is the first oral, pan Bcl-2 family inhibitor to exhibit a possible survival benefit in a randomized study. ..
  47. Lima B, Williams J, Bhattacharya S, Shah A, Andersen N, Wang A, et al. Individualized thoracic aortic replacement for the aortopathy of biscuspid aortic valve disease. J Heart Valve Dis. 2011;20:387-95 pubmed
    ..These findings convey the safety and feasibility of treating concomitant aortopathy, including arch replacement as needed, and may help tailor the specific operation needed to the patient's pathology. ..
  48. Crump J, Morrissey A, Nicholson W, Massung R, Stoddard R, Galloway R, et al. Etiology of severe non-malaria febrile illness in Northern Tanzania: a prospective cohort study. PLoS Negl Trop Dis. 2013;7:e2324 pubmed publisher
    ..An integrated approach to the syndrome of fever in resource-limited areas is needed to improve patient outcomes and to rationally target disease control efforts. ..
  49. Preece S, Nelson R, Bashir M, Jaffe T, Kim C, Haystead C. Safety of an intercostal approach for imaging-guided percutaneous drainage of subdiaphragmatic abscesses. AJR Am J Roentgenol. 2014;202:1349-54 pubmed publisher
    ..The objective of our study was to test the hypothesis that an intercostal approach to imaging-guided percutaneous subdiaphragmatic abscess drainage is as safe as a subcostal approach...
  50. Garber A, Mentz R, Al Khalidi H, Shaw L, Fiuzat M, O Connor C, et al. Clinical predictors and outcomes of patients with left ventricular thrombus following ST-segment elevation myocardial infarction. J Thromb Thrombolysis. 2016;41:365-73 pubmed publisher
    ..Prospective studies are warranted to determine whether anticoagulation in patients at increased risk for LVT improves outcomes. ..
  51. Wallace W, Li N, Andersen C, Arrossi A, Askar M, Berry G, et al. Banff study of pathologic changes in lung allograft biopsy specimens with donor-specific antibodies. J Heart Lung Transplant. 2016;35:40-8 pubmed publisher
    ..Capillary inflammation, acute lung injury, and endotheliitis significantly correlated with DSAs. The infrequently observed diffuse staining for complement 4d limits the usefulness of this stain. ..
  52. Goodman M, Saraiya M, Thompson T, Steinau M, Hernandez B, Lynch C, et al. Human papillomavirus genotype and oropharynx cancer survival in the United States of America. Eur J Cancer. 2015;51:2759-67 pubmed publisher
    ..Optimal treatment regimens for OPSCC could be tailored to each patient's HPV status and prognostic profile. ..
  53. Guhwe M, Utley Smith Q, Blessing R, Goldstein L. Routine 24-Hour Computed Tomography Brain Scan is not useful in stable patients Post Intravenous Tissue Plasminogen Activator. J Stroke Cerebrovasc Dis. 2016;25:540-2 pubmed publisher
    ..If confirmed in other cohorts, these results suggest that routine neuroimaging after IV-tPA may be safely avoided in clinically stable patients, eliminating unnecessary radiation exposure in those having CT brain and reducing costs. ..
  54. Merhi B, SHIREMAN T, Carpenter M, Kusek J, Jacques P, Pfeffer M, et al. Serum Phosphorus and Risk of Cardiovascular Disease, All-Cause Mortality, or Graft Failure in Kidney Transplant Recipients: An Ancillary Study of the FAVORIT Trial Cohort. Am J Kidney Dis. 2017;70:377-385 pubmed publisher
    ..A randomized controlled clinical trial in KTRs that assesses the potential impact of phosphorus-lowering therapy on these hard outcomes may be warranted. ..
  55. Addison S, Coleman R, Feng S, McDaniel G, Kraus V. Whole-body bone scintigraphy provides a measure of the total-body burden of osteoarthritis for the purpose of systemic biomarker validation. Arthritis Rheum. 2009;60:3366-73 pubmed publisher
  56. Patz E, Pinsky P, Gatsonis C, Sicks J, Kramer B, Tammemagi M, et al. Overdiagnosis in low-dose computed tomography screening for lung cancer. JAMA Intern Med. 2014;174:269-74 pubmed publisher
    ..38. More than 18% of all lung cancers detected by LDCT in the NLST seem to be indolent, and overdiagnosis should be considered when describing the risks of LDCT screening for lung cancer. ..
  57. Alvarez A, Maxwell G, Rodriguez G. Vacuum-assisted closure for cutaneous gastrointestinal fistula management. Gynecol Oncol. 2001;80:413-6 pubmed
    ..She was treated with total parental nutrition and the VAC device, which resulted in complete closure of the fistula. We propose that the VAC device may be a useful adjunct for the medical management of cutaneous GI fistulas. ..
  58. Amundsen C, Webster G. Sacral neuromodulation in an older, urge-incontinent population. Am J Obstet Gynecol. 2002;187:1462-5; discussion 1465 pubmed
    ..Our small cohort suggests that older urge-incontinent patients have improvement with sacral neuromodulation but cure rates may be lower than with a younger population. ..
  59. Dahl J, Soo M, Trahey G. Clinical evaluation of combined spatial compounding and adaptive imaging in breast tissue. Ultrason Imaging. 2004;26:203-16 pubmed
    ..2%. Combining both modes, however, increased cyst CNR by 32.6%, inappreciably increased target width by 1.1% and marginally decreased PBR by 2.8%. The increase in target brightness with this combined mode was 20.0% ..
  60. Kulasingam S, Kim J, Lawrence W, Mandelblatt J, Myers E, Schiffman M, et al. Cost-effectiveness analysis based on the atypical squamous cells of undetermined significance/low-grade squamous intraepithelial lesion Triage Study (ALTS). J Natl Cancer Inst. 2006;98:92-100 pubmed
    ..HPV DNA testing is an economically viable strategy for triage of ASCUS cytology. The less than perfect sensitivity of colposcopy and biopsy needs to be accounted for in future clinical guidelines and policy analyses. ..
  61. Corder E, Hefler L. Multilocus genotypes spanning estrogen metabolism associated with breast cancer and fibroadenoma. Rejuvenation Res. 2006;9:56-60 pubmed
    ..Carriage of the respective multilocus genotypes increased risk 25-fold. We conclude that GoM latent classification may be useful to identify genetic risk sets and estimate risk for individuals...
  62. Pence B, Miller W, Gaynes B, Eron J. Psychiatric illness and virologic response in patients initiating highly active antiretroviral therapy. J Acquir Immune Defic Syndr. 2007;44:159-66 pubmed
  63. Kilts J, Lin S, Lowe J, Kwatra M. Selective activation of human atrial Galpha12 and Galpha13 by Galphaq-coupled angiotensin and endothelin receptors. J Cardiovasc Pharmacol. 2007;50:299-303 pubmed
    ..These differences in the activation of Galpha12 and Galpha13 by Galphaq-coupled receptors may underlie reported differences in the functions of these receptors. ..
  64. Petrella J, Prince S, Wang L, Hellegers C, Doraiswamy P. Prognostic value of posteromedial cortex deactivation in mild cognitive impairment. PLoS ONE. 2007;2:e1104 pubmed
    ..Loss of physiological functional deactivation in the PMC may have prognostic value in preclinical AD, and could aid in profiling subgroups of MCI subjects at greatest risk for progressive cognitive decline. ..
  65. Kim C, Merkle E. Time-resolved MR angiography of the central veins of the chest. AJR Am J Roentgenol. 2008;191:1581-8 pubmed publisher
    ..The purpose of our study was to show the usefulness and limitations of contrast-enhanced time-resolved MR angiography (MRA) for imaging the central veins of the chest...
  66. Mehta R, Starr A, Lopes R, Hochman J, Widimsky P, Pieper K, et al. Incidence of and outcomes associated with ventricular tachycardia or fibrillation in patients undergoing primary percutaneous coronary intervention. JAMA. 2009;301:1779-89 pubmed publisher
    ..52; 95% CI, 0.32-0.85) (c index, 0.74). In this study, occurrence of VT/VF before or after the end of cardiac catheterization in patients presenting for primary PCI was associated with increased 90-day mortality. ..
  67. Guo A, Jahoda C. An improved method of human keratinocyte culture from skin explants: cell expansion is linked to markers of activated progenitor cells. Exp Dermatol. 2009;18:720-6 pubmed publisher
    ..By replenishing the explants with fresh medium after harvesting, further epidermal outgrowths could be obtained, offering the possibility of greatly increased keratinocyte yields for clinical applications. ..
  68. Mannelli P, Patkar A, Rozen S, Matson W, Krishnan R, Kaddurah Daouk R. Opioid use affects antioxidant activity and purine metabolism: preliminary results. Hum Psychopharmacol. 2009;24:666-75 pubmed publisher
  69. Voora D, Shah S, Spasojevic I, Ali S, Reed C, Salisbury B, et al. The SLCO1B1*5 genetic variant is associated with statin-induced side effects. J Am Coll Cardiol. 2009;54:1609-16 pubmed publisher
    ..These findings expand the results of a recent genome-wide association study of statin myopathy with CK >3x normal to milder, statin-induced, muscle side effects. ..
  70. Whitson H, Hastings S, Landerman L, Fillenbaum G, Cohen H, Johnson K. Black-white disparity in disability: the role of medical conditions. J Am Geriatr Soc. 2011;59:844-50 pubmed publisher
    ..Culturally appropriate interventions that lower the prevalence or the functional consequences of obesity and diabetes mellitus in blacks could substantially decrease this racial health disparity. ..
  71. Douglas P, Patel M, Bailey S, Dai D, Kaltenbach L, Brindis R, et al. Hospital variability in the rate of finding obstructive coronary artery disease at elective, diagnostic coronary angiography. J Am Coll Cardiol. 2011;58:801-9 pubmed publisher
    ..This institutional variation suggests that an important opportunity may exist for quality improvement. ..
  72. Samuels J, Bliss R. Analyzing variability in pain management using electronic health record data. J Nurs Care Qual. 2012;27:316-24 pubmed publisher
    ..Researchers demonstrated the use of the electronic record output for improvement purposes. ..
  73. Hoang J, Das S, Choudhury K, Yoo D, Brizel D. Using FDG-PET to measure early treatment response in head and neck squamous cell carcinoma: quantifying intrinsic variability in order to understand treatment-induced change. AJNR Am J Neuroradiol. 2013;34:1428-33 pubmed publisher
    ..Evaluation of early treatment response should be measured quantitatively in nodal disease rather than the primary tumor, and assessment of response should consider intrinsic baseline variability. ..
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