Experts and Doctors on likelihood functions in Chapel Hill, North Carolina, United States


Locale: Chapel Hill, North Carolina, United States
Topic: likelihood functions

Top Publications

  1. MacGregor B, Biddle J, Teske A. Mobile elements in a single-filament orange Guaymas Basin Beggiatoa ("Candidatus Maribeggiatoa") sp. draft genome: evidence for genetic exchange with cyanobacteria. Appl Environ Microbiol. 2013;79:3974-85 pubmed publisher
    ..We speculate that elements shared among filamentous bacterial species may have been exchanged in microbial mats and that some of them may be involved in cell differentiation. ..
  2. Evenson K, Welch V, Cascio W, Simpson R. Validation of a short rhythm strip compared to ambulatory ECG monitoring for ventricular ectopy. J Clin Epidemiol. 2000;53:491-7 pubmed
    ..However, an awareness that PVCs on a 2-min rhythm strip consistently identify high frequency PVCs on 24-hr recordings should be helpful to clinicians. ..
  3. Ortlund E, Bridgham J, Redinbo M, Thornton J. Crystal structure of an ancient protein: evolution by conformational epistasis. Science. 2007;317:1544-8 pubmed
  4. Lin D, Hu Y, Huang B. Simple and efficient analysis of disease association with missing genotype data. Am J Hum Genet. 2008;82:444-52 pubmed publisher
    ..An application to a case-control study on rheumatoid arthritis revealed several loci that deserve further investigations. ..
  5. Gaynes B, Dusetzina S, Ellis A, Hansen R, Farley J, Miller W, et al. Treating depression after initial treatment failure: directly comparing switch and augmenting strategies in STAR*D. J Clin Psychopharmacol. 2012;32:114-9 pubmed publisher
    ..Findings tentatively suggest that those who complete an initial treatment of 12 weeks or more and have a partial response with residual mild depressive severity may benefit more from augmentation relative to switching. ..
  6. Li Y, Sidore C, Kang H, Boehnke M, Abecasis G. Low-coverage sequencing: implications for design of complex trait association studies. Genome Res. 2011;21:940-51 pubmed publisher
    ..We provide guidance for investigators wishing to combine results from sequenced, genotyped, and imputed samples. ..
  7. Huynh J, Li S, Yount B, Smith A, Sturges L, Olsen J, et al. Evidence supporting a zoonotic origin of human coronavirus strain NL63. J Virol. 2012;86:12816-25 pubmed publisher
  8. Mwanza J, Budenz D, Godfrey D, Neelakantan A, Sayyad F, Chang R, et al. Diagnostic performance of optical coherence tomography ganglion cell--inner plexiform layer thickness measurements in early glaucoma. Ophthalmology. 2014;121:849-54 pubmed publisher
  9. Wright F, Sullivan P, Brooks A, Zou F, Sun W, Xia K, et al. Heritability and genomics of gene expression in peripheral blood. Nat Genet. 2014;46:430-7 pubmed publisher
    ..Our results provide a new resource toward understanding the genetic control of transcription. ..

More Information


  1. Hartmann K, Barrett K, Reid V, McMahon M, Miller W. Clinical usefulness of white blood cell count after cesarean delivery. Obstet Gynecol. 2000;96:295-300 pubmed
    ..To examine changes in white blood cell (WBC) count after cesarean and estimate risk of postoperative infection...
  2. Jones C, Begun D. Parallel evolution of chimeric fusion genes. Proc Natl Acad Sci U S A. 2005;102:11373-8 pubmed publisher
    ..Our data indicate that shifting away from ancestral functions may be a critical step early in the evolution of chimeric fusion genes. We suggest that the patterns we observed are both general and predictive...
  3. Hurwitz A, Brice J, Overby B, Evenson K. Directed use of the Cincinnati Prehospital Stroke Scale by laypersons. Prehosp Emerg Care. 2005;9:292-6 pubmed
  4. Hartmann S, Vision T. Using ESTs for phylogenomics: can one accurately infer a phylogenetic tree from a gappy alignment?. BMC Evol Biol. 2008;8:95 pubmed publisher
  5. Smith Roe S, Patel S, Zhou Y, Simpson D, Rao S, Ibrahim J, et al. Separation of intra-S checkpoint protein contributions to DNA replication fork protection and genomic stability in normal human fibroblasts. Cell Cycle. 2013;12:332-45 pubmed publisher
    ..These data reveal a complex and coordinated program of genome maintenance enforced by proteins known for their intra-S checkpoint function. ..
  6. Trumble I, Allmon A, Archin N, Rigdon J, Francis O, Baldoni P, et al. SLDAssay: A software package and web tool for analyzing limiting dilution assays. J Immunol Methods. 2017;450:10-16 pubmed publisher
    ..Additional advantages of using exact methods are also discussed. ..
  7. Blanco I, Kuchenbaecker K, Cuadras D, Wang X, Barrowdale D, de Garibay G, et al. Assessing associations between the AURKA-HMMR-TPX2-TUBG1 functional module and breast cancer risk in BRCA1/2 mutation carriers. PLoS ONE. 2015;10:e0120020 pubmed publisher
    ..Together, the results of this study support the hypothesis of a causative link between altered function of AURKA-HMMR-TPX2-TUBG1 and breast carcinogenesis in BRCA1/2 mutation carriers. ..