Experts and Doctors on humans in Raleigh, North Carolina, United States


Locale: Raleigh, North Carolina, United States
Topic: humans

Top Publications

  1. Kulkarni N, Karavanich C, Atchley W, Anholt R. Characterization and differential expression of a human gene family of olfactomedin-related proteins. Genet Res. 2000;76:41-50 pubmed
    ..Future studies can now assess whether other members of this gene family, like TIGR/myocilin, are also associated with human disease processes. ..
  2. Helton T, Horne W. Alternative splicing of the beta 4 subunit has alpha1 subunit subtype-specific effects on Ca2+ channel gating. J Neurosci. 2002;22:1573-82 pubmed
    ..Our data are best explained by a model in which distinct modes of activation and inactivation result from beta-subunit splice variant-specific interactions with an alpha1 subunit gating structure. ..
  3. Kirkwood S, Myers J. Safety or marketing? Why we decorate our vehicles the way that we do. JEMS. 2007;32:46-8, 50-3 pubmed
  4. Hotchkiss A, Rider C, Blystone C, Wilson V, Hartig P, Ankley G, et al. Fifteen years after "Wingspread"--environmental endocrine disrupters and human and wildlife health: where we are today and where we need to go. Toxicol Sci. 2008;105:235-59 pubmed publisher
  5. Thakur S, White D, McDermott P, Zhao S, Kroft B, Gebreyes W, et al. Genotyping of Campylobacter coli isolated from humans and retail meats using multilocus sequence typing and pulsed-field gel electrophoresis. J Appl Microbiol. 2009;106:1722-33 pubmed publisher
    ..To determine the antimicrobial resistant profiles and clonality of Campylobacter coli isolated from clinically ill humans and retail meats...
  6. Noack Cooper K, Sommerich C, Mirka G. College students and computers: assessment of usage patterns and musculoskeletal discomfort. Work. 2009;32:285-98 pubmed publisher
  7. Apparao K, Newman D, Zhang H, Khosla J, Randell S, Sannes P. Temporal changes in expression of FoxA1 and Wnt7A in isolated adult human alveolar epithelial cells enhanced by heparin. Anat Rec (Hoboken). 2010;293:938-46 pubmed publisher
    ..Collectively, these factors may act to modulate differentiation in the adult human pulmonary alveolus. ..
  8. Aoi M, Rourke B. Interspecific and intragenic differences in codon usage bias among vertebrate myosin heavy-chain genes. J Mol Evol. 2011;73:74-93 pubmed publisher
    ..Therefore, patterns of codon usage in MyHC genes are consistent with models supporting SANE as a major force shaping codon usage. ..
  9. Gera N, Hill A, White D, Carbonell R, Rao B. Design of pH sensitive binding proteins from the hyperthermophilic Sso7d scaffold. PLoS ONE. 2012;7:e48928 pubmed publisher
    ..Therefore, further studies are needed to evaluate if the Sso7d mutants identified in this study are indeed useful as affinity ligands in chromatography. ..

More Information

Publications439 found, 100 shown here

  1. Harvey J, Hong H, Bhusari S, Ton T, Wang Y, Foley J, et al. F344/NTac Rats Chronically Exposed to Bromodichloroacetic Acid Develop Mammary Adenocarcinomas With Mixed Luminal/Basal Phenotype and Tgfβ Dysregulation. Vet Pathol. 2016;53:170-81 pubmed publisher
  2. Garner D, Kathariou S. Fresh Produce-Associated Listeriosis Outbreaks, Sources of Concern, Teachable Moments, and Insights. J Food Prot. 2016;79:337-44 pubmed publisher
  3. Clowse M, Förger F, Hwang C, Thorp J, Dolhain R, van Tubergen A, et al. Minimal to no transfer of certolizumab pegol into breast milk: results from CRADLE, a prospective, postmarketing, multicentre, pharmacokinetic study. Ann Rheum Dis. 2017;76:1890-1896 pubmed publisher
    ..These findings are reassuring and support continuation of CZP treatment during breast feeding. NCT02154425; Results. ..
  4. Cherrington N, Cao Y, Cherrington J, Rose R, Hodgson E. Physiological factors affecting protein expression of flavin-containing monooxygenases 1, 3 and 5. Xenobiotica. 1998;28:673-82 pubmed
    ..5. An event takes place after birth but before puberty that confers the ability to produce FMO3. The developmental pattern observed for mouse FMO3 is similar to human FMO3. ..
  5. McDonald S. Network effects across the earnings distribution: payoffs to visible and invisible job finding assistance. Soc Sci Res. 2015;49:299-313 pubmed publisher
    ..These findings challenge conventional wisdom on contact effects and advance understanding of how social networks affect wage attainment and inequality. ..
  6. Steingold S, Sharp N, McGahan M, Hughes C, Dunn S, Page R. Characterization of canine MDR1 mRNA: its abundance in drug resistant cell lines and in vivo. Anticancer Res. 1998;18:393-400 pubmed
    ..Expression of MDR1 mRNA correlates with in vitro drug sensitivity but does not correlate with in vivo doxorubicin sensitivity in canine lymphoma. ..
  7. Tully D, Jones F, Tully M. Donor milk: what's in it and what's not. J Hum Lact. 2001;17:152-5 pubmed
    ..This article reviews some of the critical components of human milk and what is currently known about the effects of Holder pasteurization on their biological activity. ..
  8. Lin K, Park J, Crews A, Li Y, Adler K. Protease-activated receptor-2 (PAR-2) is a weak enhancer of mucin secretion by human bronchial epithelial cells in vitro. Int J Biochem Cell Biol. 2008;40:1379-88 pubmed
    ..The results suggest that, since PAR-2 activation only weakly increases mucin secretion by human airway epithelial cells in vitro, PAR-2 probably is not a significant contributor to mucin hypersecretion in inflamed airways. ..
  9. LaForce C, Gentile D, Skoner D. A randomized, double-blind, parallel-group, multicenter, placebo-controlled study of the safety and efficacy of extended-release guaifenesin/pseudoephedrine hydrochloride for symptom relief as an adjunctive therapy to antibiotic treatment of acute re. Postgrad Med. 2008;120:53-9 pubmed publisher
  10. Scarantino C, Beyer G. The Dose Verification System (DVS) for cancer patients receiving radiation therapy. Expert Rev Med Devices. 2008;5:679-85 pubmed publisher
    ..The device is an important step to enable physicians to expand the concept of individualization of therapy. ..
  11. Hannas B, LeBlanc G. Expression and ecdysteroid responsiveness of the nuclear receptors HR3 and E75 in the crustacean Daphnia magna. Mol Cell Endocrinol. 2010;315:208-18 pubmed publisher
    ..The marginal induction of E75 by 20-hydroxyecdysone may represent limited, tissue or cell-type-specific induction of this transcription factor. ..
  12. Casper J, Harrolle M, Kelley K. Gender differences in self-report physical activity and park and recreation facility use among Latinos in Wake County, North Carolina. Ann Behav Med. 2013;45 Suppl 1:S49-54 pubmed publisher
    ..Even though parks/recreation services are viewed as viable options for Latinos' PA, the study identified gender differences that inform health promotion interventions to be more effective in targeting Latinos. ..
  13. Maggi R, Ericson M, Mascarelli P, Bradley J, Breitschwerdt E. Bartonella henselae bacteremia in a mother and son potentially associated with tick exposure. Parasit Vectors. 2013;6:101 pubmed publisher
    ..henselae organism has been visualized in and amplified from a striae lesion. As the tick bites occurred three years prior to documentation of B. henselae bacteremia, the mode of transmission could not be determined. ..
  14. Maharshak N, Huh E, Paiboonrungruang C, Shanahan M, Thurlow L, Herzog J, et al. Enterococcus faecalis Gelatinase Mediates Intestinal Permeability via Protease-Activated Receptor 2. Infect Immun. 2015;83:2762-70 pubmed publisher
    ..Our investigations demonstrate that GelE from E. faecalis can regulate enteric epithelial permeability via PAR2. ..
  15. Bai S, Xiang Q, Finn A. Evaluation of the Pharmacokinetics of Single- and Multiple-dose Buprenorphine Buccal Film in Healthy Volunteers. Clin Ther. 2016;38:358-69 pubmed publisher
    ..These pharmacokinetic results suggest that therapeutic buprenorphine plasma concentrations can be obtained with BBUP across a wide dose range in a shorter time than other (eg, transdermal) dosage forms. ..
  16. Garcia E, Wolak Dinsmore J, Wang Z, Li X, Bennett D, Connelly M, et al. NMR quantification of trimethylamine-N-oxide in human serum and plasma in the clinical laboratory setting. Clin Biochem. 2017;50:947-955 pubmed publisher
    ..Moreover, assay performance enables the levels of TMAO to be quantified in serum or plasma at clinically actionable concentrations for the assessment of cardiovascular disease risks and individualized dietary monitoring. ..
  17. Altier C, Suyemoto M, Lawhon S. Regulation of Salmonella enterica serovar typhimurium invasion genes by csrA. Infect Immun. 2000;68:6790-7 pubmed
  18. Booth B, Sandifer T, Martin E, Martin L. IL-13-induced proliferation of airway epithelial cells: mediation by intracellular growth factor mobilization and ADAM17. Respir Res. 2007;8:51 pubmed
    ..Thus, IL-13-induced, ADAM17-mediated release of TGFalpha, and subsequent epithelial cell proliferation, could contribute to the epithelial hypertrophy, as well as other features, associated with airway remodeling in allergic asthma. ..
  19. Galvão R, Kota U, Soderblom E, Goshe M, Boss W. Characterization of a new family of protein kinases from Arabidopsis containing phosphoinositide 3/4-kinase and ubiquitin-like domains. Biochem J. 2008;409:117-27 pubmed
    ..These UBL-domain-containing AtPI4Ks correspond to a new PIKK subfamily of protein kinases. Furthermore, UFD1 and RPN10 phosphorylation represents an additional mechanism by which their function can be regulated. ..
  20. Tompkins L, Wallace A. Mechanisms of cytochrome P450 induction. J Biochem Mol Toxicol. 2007;21:176-81 pubmed
    ..The mechanisms by which CYP3A4, 2B6, and 1A1 are induced involving the activation of the transcription factors pregnane X receptor (PXR), constitutive androstane receptor (CAR), and aryl hydrocarbon receptor (AhR) will be discussed. ..
  21. Viazis S, Farkas B, Jaykus L. Inactivation of bacterial pathogens in human milk by high-pressure processing. J Food Prot. 2008;71:109-18 pubmed
    ..These data suggest that HPP may be a promising alternative for pasteurization of human milk. Further research should evaluate the efficacy of HPP in the inactivation of relevant viral pathogens. ..
  22. Ramasubramanian M, Barham O, Swaminathan V. Mechanics of a mosquito bite with applications to microneedle design. Bioinspir Biomim. 2008;3:046001 pubmed publisher
    ..This understanding may be useful in designing painless needle insertion systems as opposed to miniaturized hypodermic needles. ..
  23. Deiters A. Small molecule modifiers of the microRNA and RNA interference pathway. AAPS J. 2010;12:51-60 pubmed publisher
    ..Thus, the activation of tumor-suppressive miRNAs and the inhibition of oncogenic miRNAs by small molecules have the potential to provide a fundamentally new approach for the development of cancer therapeutics. ..
  24. McCalla Martin A, Chen X, Linder K, Estrada J, Piedrahita J. Varying phenotypes in swine versus murine transgenic models constitutively expressing the same human Sonic hedgehog transcriptional activator, K5-HGLI2 Delta N. Transgenic Res. 2010;19:869-87 pubmed publisher
    ..These findings indicate a need for a multiple species animal model approach in order to better understand the role of Gli2 in mammalian skin. ..
  25. Banks H, Thompson W, Peligero C, Giest S, Argilaguet J, Meyerhans A. A division-dependent compartmental model for computing cell numbers in CFSE-based lymphocyte proliferation assays. Math Biosci Eng. 2012;9:699-736 pubmed publisher
    ..Variability in cellular autofluorescence is found to play a significant role in the data, as well. Finally, the compartmental model is compared to previous work, and statistical aspects of the experimental data are discussed. ..
  26. Spruiell K, Jones D, Cullen J, Awumey E, Gonzalez F, Gyamfi M. Role of human pregnane X receptor in high fat diet-induced obesity in pre-menopausal female mice. Biochem Pharmacol. 2014;89:399-412 pubmed publisher
    ..Finally, these data identify PXR-humanized mice as a promising in vivo research model for studying obesity and diabetes in women. ..
  27. Sun X, Waller A, Yeatts K, Thie L. Pollen concentration and asthma exacerbations in Wake County, North Carolina, 2006-2012. Sci Total Environ. 2016;544:185-91 pubmed publisher
    ..These findings have important implications for optimizing targeted allergic disease prevention and management, and helping understand the etiology of ambient exposure-induced allergic diseases. ..
  28. Graham P, Kim M, Clinton Sherrod A, Yaros A, Richmond A, Jackson M, et al. What is the role of culture, diversity, and community engagement in transdisciplinary translational science?. Transl Behav Med. 2016;6:115-24 pubmed publisher
    ..Our comprehensive model for incorporating culture and diversity into translational research provides a basis for further discussion and translational science development. ..
  29. Planchart A, Mattingly C, Allen D, Ceger P, Casey W, Hinton D, et al. Advancing toxicology research using in vivo high throughput toxicology with small fish models. ALTEX. 2016;33:435-452 pubmed publisher
  30. Boone D. Complications of iliac crest graft and bone grafting alternatives in foot and ankle surgery. Foot Ankle Clin. 2003;8:1-14 pubmed
    ..In the future, with continued research, the fields of tissue engineering and gene therapy will provide even better options for nonautogenous bone graft material...
  31. Powers R. Organization of a hospital-based victim decontamination plan using the incident command structure. Disaster Manag Response. 2007;5:119-23 pubmed
    ..This article describes the specific roles and responsibilities included in an incident command system-based hospital decontamination plan than has been used successfully in a multi-hospital system. ..
  32. Yang H, Gurgel P, Williams D, Bobay B, Cavanagh J, Muddiman D, et al. Binding site on human immunoglobulin G for the affinity ligand HWRGWV. J Mol Recognit. 2010;23:271-82 pubmed publisher
    ..The results support the fact that a peptide as small as a hexamer can have specific interactions with large proteins such as hIgG. ..
  33. Van Vleet L, Hubble M. Time to first compression using Medical Priority Dispatch System compression-first dispatcher-assisted cardiopulmonary resuscitation protocols. Prehosp Emerg Care. 2012;16:242-50 pubmed publisher
    ..Efforts should continue to focus on improving this key, and modifiable, determinant of cardiac arrest survival. ..
  34. Naik A, Menegatti S, Reese H, Gurgel P, Carbonell R. Process for purification of monoclonal antibody expressed in transgenic Lemna plant extract using dextran-coated charcoal and hexamer peptide affinity resin. J Chromatogr A. 2012;1260:61-6 pubmed publisher
    ..The final yield and purity of the MAb obtained were 90% and 96% respectively. The performance of the hexamer peptide resin after the pretreatment step was found to be similar to that obtained with a commercial Protein A resin. ..
  35. Gettings K, Kiesler K, Faith S, Montano E, Baker C, Young B, et al. Sequence variation of 22 autosomal STR loci detected by next generation sequencing. Forensic Sci Int Genet. 2016;21:15-21 pubmed publisher
    ..As expected, repeat region sequences which had not previously been reported in forensic literature were identified. ..
  36. Collins C. Challenges of Recruitment and Retention in Rural Areas. N C Med J. 2016;77:99-101 pubmed publisher
    ..This will require further refinement of the critical workforce definition, and it brings to the forefront the fact that a variety of new partnerships will be key to achieving the objective of healthy rural communities. ..
  37. Maccioli G. Dexmedetomidine to facilitate drug withdrawal. Anesthesiology. 2003;98:575-7 pubmed
  38. Longo A, Guanga G, Rose R. Crystal structure of E47-NeuroD1/beta2 bHLH domain-DNA complex: heterodimer selectivity and DNA recognition. Biochemistry. 2008;47:218-29 pubmed
    ..Orienting E47-NeuroD1 on promoters may foster protein-protein contacts essential to initiate transcription. ..
  39. Gittard S, Miller P, Boehm R, Ovsianikov A, Chichkov B, Heiser J, et al. Multiphoton microscopy of transdermal quantum dot delivery using two photon polymerization-fabricated polymer microneedles. Faraday Discuss. 2011;149:171-85; discussion 227-45 pubmed
    ..The microneedle device was used to inject quantum dots into porcine skin; imaging of the quantum dots was performed using multiphoton microscopy. ..
  40. Nasir A, Goldstein B, van Cleeff M, Swick L. Clinical evaluation of safety and efficacy of a new topical treatment for onychomycosis. J Drugs Dermatol. 2011;10:1186-91 pubmed
    ..This study describes a new topical medical device with safety and efficacy profiles that compare favorably to results reported for topically applied onychomycosis drug treatments. ..
  41. Sternhagen L, Allen J. Growth rates of a human colon adenocarcinoma cell line are regulated by the milk protein alpha-lactalbumin. Adv Exp Med Biol. 2001;501:115-20 pubmed
    ..These results suggest that alpha-lactalbumin in milk may promote health by inhibiting growth of potential cancer cells. Further studies will identify the role of calcium in the bioactivity of alpha-lactalbumin. ..
  42. Park J, He F, Martin L, Li Y, Chorley B, Adler K. Human neutrophil elastase induces hypersecretion of mucin from well-differentiated human bronchial epithelial cells in vitro via a protein kinase C{delta}-mediated mechanism. Am J Pathol. 2005;167:651-61 pubmed
    ..Inhibition of PKCdelta attenuated HNE-mediated mucin secretion. The results suggest HNE stimulation of mucin release by human airway epithelial cells involves intracellular activation of PKC, specifically the delta isoform. ..
  43. Maggi R, Chomel B, Hegarty B, Henn J, Breitschwerdt E. A Bartonella vinsonii berkhoffii typing scheme based upon 16S-23S ITS and Pap31 sequences from dog, coyote, gray fox, and human isolates. Mol Cell Probes. 2006;20:128-34 pubmed
    ..Strain typing may help to better define the reservoir potential, carriership patterns, modes of transmission, and geographic distribution for each B. vinsonii berkhoffii type...
  44. Liu J, Hughes Oliver J, Menius J. Domain-enhanced analysis of microarray data using GO annotations. Bioinformatics. 2007;23:1225-34 pubmed The two experimental data sets used in our analysis are available in R as Bioconductor packages, 'ALL' and 'golubEsets' ( Supplementary data are available at Bioinformatics online. ..
  45. Eckert R, Jones S. Regulation of VASP serine 157 phosphorylation in human neutrophils after stimulation by a chemoattractant. J Leukoc Biol. 2007;82:1311-21 pubmed
    ..Adhesion does not appear to be an important regulator of the state of VASP Ser 157 phosphorylation in chemoattractant-stimulated neutrophils. ..
  46. Sackett D, Aday D, Rice J, Cope W, Buchwalter D. Does proximity to coal-fired power plants influence fish tissue mercury?. Ecotoxicology. 2010;19:1601-11 pubmed publisher
  47. Suyemoto M, Spears P, Hamrick T, Barnes J, Havell E, Orndorff P. Factors associated with the acquisition and severity of gestational listeriosis. PLoS ONE. 2010;5:e13000 pubmed publisher
    ..Our results also suggest that while gravid animals are competent to contain an enteric infection, enteric carriage rate may be more of a factor in defining disease incidence than previously considered. ..
  48. Doraiswamy A, Ovsianikov A, Gittard S, Monteiro Riviere N, Crombez R, Montalvo E, et al. Fabrication of microneedles using two photon polymerization for transdermal delivery of nanomaterials. J Nanosci Nanotechnol. 2010;10:6305-12 pubmed
    ..Our results suggest that two photon polymerization may be used to create microneedle arrays for transdermal delivery of nanoscale pharmacologic agents. ..
  49. Irvin S, Zurney J, Ooms L, Chappell J, Dermody T, Sherry B. A single-amino-acid polymorphism in reovirus protein ?2 determines repression of interferon signaling and modulates myocarditis. J Virol. 2012;86:2302-11 pubmed publisher
    ..These results demonstrate that a single amino acid difference between viruses can dictate virus strain-specific differences in suppression of the host IFN-? response and, consequently, damage to the heart. ..
  50. Wilson E, Perrin M, Fogleman A, Chetwynd E. The intricacies of induced lactation for same-sex mothers of an adopted child. J Hum Lact. 2015;31:64-7 pubmed publisher
    ..However, because of the increased complexity of the immediate postpartum period and concerns with defining parental roles in a same-sex marriage, maintenance of milk production was difficult. ..
  51. Kakumanu M, Ponnusamy L, Sutton H, Meshnick S, Nicholson W, Apperson C. Development and Validation of an Improved PCR Method Using the 23S-5S Intergenic Spacer for Detection of Rickettsiae in Dermacentor variabilis Ticks and Tissue Samples from Humans and Laboratory Animals. J Clin Microbiol. 2016;54:972-9 pubmed publisher
    ..CandidatusRickettsia amblyommii,"R. montanensis,R. felis, andR. belliiwere frequently identified species, along with some potentially novelRickettsiastrains that were closely related toR. belliiandR. conorii. ..
  52. Olivry T, Marsella R, Hillier A. The ACVD task force on canine atopic dermatitis (XXIII): are essential fatty acids effective?. Vet Immunol Immunopathol. 2001;81:347-62 pubmed
    ..In these trials, clinical efficacy should be evaluated in relation to plasma and cutaneous EFA treatment-induced alterations. ..
  53. Wogalter M, Conzola V, Smith Jackson T. Research-based guidelines for warning design and evaluation. Appl Ergon. 2002;33:219-30 pubmed
    ..Researchers, practitioners, and manufacturers can use these guidelines in various contexts to reduce the likelihood that injury and product damage from exposure to a hazard will occur. ..
  54. Holt S, Drew R. Echinocandins: addressing outstanding questions surrounding treatment of invasive fungal infections. Am J Health Syst Pharm. 2011;68:1207-20 pubmed publisher
    ..Clinical data continue to support the use of echinocandins as a safe and well-tolerated treatment option for candidemia and invasive aspergillosis. ..
  55. Dean G, Pedersen N. Cytokine response in multiple lymphoid tissues during the primary phase of feline immunodeficiency virus infection. J Virol. 1998;72:9436-40 pubmed
    ..Although limited in scope, the present study confirms the usefulness of the FIV infection model in studying early cytokine events that lead to the secondary subclinical carrier state typical of most lentivirus infections. ..
  56. Davis J, Mirka G. Transverse-contour modeling of trunk muscle-distributed forces and spinal loads during lifting and twisting. Spine (Phila Pa 1976). 2000;25:180-9 pubmed
  57. Reddy D. The clinical potentials of endogenous neurosteroids. Drugs Today (Barc). 2002;38:465-85 pubmed
    ..Future studies may provide important new evidence that may not only explain acute actions of stress, but also reveal the clinical importance of neurosteroid mechanisms during chronic stress. ..
  58. Goralska M, Holley B, McGahan M. Identification of a mechanism by which lens epithelial cells limit accumulation of overexpressed ferritin H-chain. J Biol Chem. 2003;278:42920-6 pubmed
  59. Kononchik J, Hernandez R, Brown D. An alternative pathway for alphavirus entry. Virol J. 2011;8:304 pubmed publisher
    ..In this review we compare the data which support the two models and make the case for an alternative pathway of entry by alphaviruses. ..
  60. Herfel T, Jacobi S, Lin X, Fellner V, Walker D, Jouni Z, et al. Polydextrose enrichment of infant formula demonstrates prebiotic characteristics by altering intestinal microbiota, organic acid concentrations, and cytokine expression in suckling piglets. J Nutr. 2011;141:2139-45 pubmed publisher
    ..In summary, PDX enrichment of infant formula resulted in a prebiotic effect by increasing ileal lactobacilli and propionic and lactic acid concentrations and decreasing pH with associated alterations in ileal cytokine expression. ..
  61. Stebbing R, Irvin S, Rivera Serrano E, Boehme K, Ikizler M, Yoder J, et al. An ITAM in a nonenveloped virus regulates activation of NF-?B, induction of beta interferon, and viral spread. J Virol. 2014;88:2572-83 pubmed publisher
    ..This first demonstration of a functional ITAM in a nonenveloped virus presents a new mechanism for viral ITAM-mediated signaling with likely organ-specific consequences in the host. ..
  62. Ran D, Daye Z. Gene expression variability and the analysis of large-scale RNA-seq studies with the MDSeq. Nucleic Acids Res. 2017;45:e127 pubmed publisher
    ..Specifically, the analysis of gene expression variability with the MDSeq on the GTEx human brain tissue data has identified pathways associated with common neurodegenerative disorders when gene expression means were conserved. ..
  63. Mackenzie E, Tsuji Y. Elevated intracellular calcium increases ferritin H expression through an NFAT-independent post-transcriptional mechanism involving mRNA stabilization. Biochem J. 2008;411:107-13 pubmed
    ..Taken together, these results suggest that ionomycin-mediated induction of ferritin H may occur in an NFAT-independent manner but through post-transcriptional stabilization of the ferritin H mRNA. ..
  64. Wallace A, Cao Y, Chandramouleeswaran S, Cidlowski J. Lysine 419 targets human glucocorticoid receptor for proteasomal degradation. Steroids. 2010;75:1016-23 pubmed publisher
    ..Together these results suggest that the proteasome and the identified PEST degradation motif limit steroid-dependent human glucocorticoid receptor signaling. ..
  65. Huggins J, Brown J, Capehart B, Townsend M, Legge J, Melnyk S. Medication adherence in combat veterans with traumatic brain injury. Am J Health Syst Pharm. 2011;68:254-8 pubmed publisher
    ..Factors associated with increased adherence included taking more than five maintenance medications, living with a spouse or significant other, owning a memory-assistance device, and a comorbid diagnosis of PTSD. ..
  66. McNamara S. Incivility in nursing: unsafe nurse, unsafe patients. AORN J. 2012;95:535-40 pubmed publisher
  67. Stacey R, Andersen M, Haag J, Hall M, McLeod G, Upadhya B, et al. Right ventricular morphology and systolic function in left ventricular noncompaction cardiomyopathy. Am J Cardiol. 2014;113:1018-23 pubmed publisher
    ..04 and p <0.001, respectively). In conclusion, RV dysfunction in a morphologic LVNC population is strongly associated with adverse clinical events. LVNC is associated with increased trabeculations of the RV apex. ..
  68. Kaur P, Wu D, Lin J, Countryman P, Bradford K, Erie D, et al. Enhanced electrostatic force microscopy reveals higher-order DNA looping mediated by the telomeric protein TRF2. Sci Rep. 2016;6:20513 pubmed publisher
    ..Revealing DNA paths in TRF2 complexes provides new mechanistic insights into structure-function relationships underlying telomere maintenance pathways. ..
  69. Karoly E, Rose R. Sequencing, expression, and characterization of cDNA expressed flavin-containing monooxygenase 2 from mouse. J Biochem Mol Toxicol. 2001;15:300-8 pubmed
    ..coli fractions utilizing NADPH oxidation demonstrated that the mouse FMO2 enzyme also exhibits catalytic activity towards thiourea, trimethylamine, and the insecticide phorate. ..
  70. Ganley O, Pendergast W, Wilkerson M, Mattingly D. Outcome study of substance impaired physicians and physician assistants under contract with North Carolina Physicians Health Program for the period 1995-2000. J Addict Dis. 2005;24:1-12 pubmed
    ..With paucity of data on physician assistants in the literature, the present study may be one of the first to single out this group and compare their recovery rates with those of physicians while receiving similar NCPHP services. ..
  71. Hawkridge A, Wysocky R, Petitte J, Anderson K, Mozdziak P, Fletcher O, et al. Measuring the intra-individual variability of the plasma proteome in the chicken model of spontaneous ovarian adenocarcinoma. Anal Bioanal Chem. 2010;398:737-49 pubmed publisher
    ..Ovomacroglobulin (ovostatin) was found to increase (p?<?0.001) over a 6 month period in the late-stage EOC bird providing an initial candidate protein for further investigation. ..
  72. Winham S, Slater A, Motsinger Reif A. A comparison of internal validation techniques for multifactor dimensionality reduction. BMC Bioinformatics. 2010;11:394 pubmed publisher
    ..This implies 3WS may be a powerful and computationally efficient approach to screen for epistatic effects, and could be used to identify candidate interactions in large-scale genetic studies. ..
  73. Biswas S, Buhrman G, Gagnon K, Mattos C, Brown B, Maxwell E. Comparative analysis of the 15.5kD box C/D snoRNP core protein in the primitive eukaryote Giardia lamblia reveals unique structural and functional features. Biochemistry. 2011;50:2907-18 pubmed publisher
    ..lamblia 15.5kD protein occupies a unique position in the evolution of this box C/D RNP core protein retaining structural and functional features characteristic of both archaeal L7Ae and higher eukaryotic 15.5kD homologues...
  74. Omori E, Matsumoto K, Ninomiya Tsuji J. Non-canonical ?-catenin degradation mediates reactive oxygen species-induced epidermal cell death. Oncogene. 2011;30:3336-44 pubmed publisher
    ..Upregulation of the intact ?-catenin blocked ROS accumulation and caspase activation. These results indicate that a feed-forward loop consisting of ROS, caspases activation and ?-catenin degradation induces epidermal cell death. ..
  75. Lu W, Zhang H, Zeng D. Variable selection for optimal treatment decision. Stat Methods Med Res. 2013;22:493-504 pubmed publisher
    ..Theoretical properties of the new estimator are studied. Its empirical performance is evaluated using simulation studies and further illustrated with an application to an AIDS clinical trial. ..
  76. Wiegers T, Davis A, Mattingly C. Collaborative biocuration--text-mining development task for document prioritization for curation. Database (Oxford). 2012;2012:bas037 pubmed publisher
    ..In this article, we present a detailed description of the challenge and a summary of the results. ..
  77. Doty P, Hebert D, Mathy F, Byrnes W, Zackheim J, Simontacchi K. Development of lacosamide for the treatment of partial-onset seizures. Ann N Y Acad Sci. 2013;1291:56-68 pubmed publisher
  78. Blackledge M, Worthington R, Melander C. Biologically inspired strategies for combating bacterial biofilms. Curr Opin Pharmacol. 2013;13:699-706 pubmed publisher
    ..Such approaches have the potential to, in combination with conventional antibiotics, play an important role in the eradication of biofilm based bacterial infections. ..
  79. Anholt R, Carbone M. A molecular mechanism for glaucoma: endoplasmic reticulum stress and the unfolded protein response. Trends Mol Med. 2013;19:586-93 pubmed publisher
    ..This mechanism of POAG is reminiscent of other age-dependent neurodegenerative diseases that involve accumulation of protein aggregates. ..
  80. Zito R, De Coster S. Family Structure, Maternal Dating, and Sexual Debut: Extending the Conceptualization of Instability. J Youth Adolesc. 2016;45:1003-19 pubmed publisher
    ..Among males, the influence of maternal dating on early sexual debut is fully explained by the learning of permissive sexual attitudes. ..
  81. Hall T, Brown J. Archaeal RNase P has multiple protein subunits homologous to eukaryotic nuclear RNase P proteins. RNA. 2002;8:296-306 pubmed
    ..RNase P in Archaea is therefore composed of an RNA subunit similar to bacterial RNase P RNA and multiple protein subunits similar to those in the eukaryotic nucleus...
  82. Safwat N, Ninomiya Tsuji J, Gore A, Miller W. Transforming growth factor beta-activated kinase 1 is a key mediator of ovine follicle-stimulating hormone beta-subunit expression. Endocrinology. 2005;146:4814-24 pubmed publisher
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