Experts and Doctors on homeostasis in Raleigh, North Carolina, United States


Locale: Raleigh, North Carolina, United States
Topic: homeostasis

Top Publications

  1. Omori E, Matsumoto K, Sanjo H, Sato S, Akira S, Smart R, et al. TAK1 is a master regulator of epidermal homeostasis involving skin inflammation and apoptosis. J Biol Chem. 2006;281:19610-7 pubmed
    ..Our results demonstrate that TAK1 is a master regulator of TNF signaling in skin and regulates skin inflammation and keratinocyte death. ..
  2. Petty C, Tompkins M, Tompkins W. Transforming growth factor-beta/transforming growth factor-betaRII signaling may regulate CD4+CD25+ T-regulatory cell homeostasis and suppressor function in feline AIDS lentivirus infection. J Acquir Immune Defic Syndr. 2008;47:148-60 pubmed
  3. Chilcoat C, Sharief Y, Jones S. Tonic protein kinase A activity maintains inactive beta2 integrins in unstimulated neutrophils by reducing myosin light-chain phosphorylation: role of myosin light-chain kinase and Rho kinase. J Leukoc Biol. 2008;83:964-71 pubmed publisher
    ..These findings demonstrate that tonic PKA activity prevents activation of beta2 integrins and adhesion by inhibiting MLC phosphorylation via a MLCK-dependent but ROCK-independent pathway. ..
  4. Hansen S, Trakooljul N, Spears J, Liu H. Age and dietary iron affect expression of genes involved in iron acquisition and homeostasis in young pigs. J Nutr. 2010;140:271-7 pubmed publisher
    ..Additionally, the expression of some genes examined in this study was affected by age, suggesting age dependency of Fe metabolism in pigs. ..
  5. Li Q, Lin Y, Sun Y, Song J, Chen H, Zhang X, et al. Splice variant of the SND1 transcription factor is a dominant negative of SND1 members and their regulation in Populus trichocarpa. Proc Natl Acad Sci U S A. 2012;109:14699-704 pubmed publisher
    ..PtrSND1-A2(IR) may contribute to transcriptional homeostasis to avoid deleterious effects on xylogenesis and plant growth...
  6. Aoi M, Hu K, Lo M, Selim M, Olufsen M, Novak V. Impaired cerebral autoregulation is associated with brain atrophy and worse functional status in chronic ischemic stroke. PLoS ONE. 2012;7:e46794 pubmed publisher
    ..002). Our results indicate that better dynamic cerebral perfusion regulation is associated with less atrophy and better long-term functional status in older adults with chronic ischemic infarctions. ..
  7. Selle K, Klaenhammer T. Genomic and phenotypic evidence for probiotic influences of Lactobacillus gasseri on human health. FEMS Microbiol Rev. 2013;37:915-35 pubmed publisher
    ..gasseri in probiotic applications is substantiated by clinical trial data displaying maintenance of vaginal homeostasis, mitigation of Helicobacter pylori infection, and amelioration of diarrhea...
  8. Samira R, Stallmann A, Massenburg L, Long T. Ironing out the issues: integrated approaches to understanding iron homeostasis in plants. Plant Sci. 2013;210:250-9 pubmed publisher
    ..A broad perspective of how Fe localization data might one day be integrated with large-scale data to create models for Fe homeostasis is presented. ..
  9. Bogdan A, Miyazawa M, Hashimoto K, Tsuji Y. Regulators of Iron Homeostasis: New Players in Metabolism, Cell Death, and Disease. Trends Biochem Sci. 2016;41:274-286 pubmed publisher
    ..We also discuss emerging roles of iron in apoptosis and a novel iron-dependent cell death pathway termed 'ferroptosis', the dysregulation of iron metabolism in human pathologies, and the use of iron chelators in cancer therapy. ..

More Information


  1. Harned J, Ferrell J, Lall M, Fleisher L, Nagar S, Goralska M, et al. Altered ferritin subunit composition: change in iron metabolism in lens epithelial cells and downstream effects on glutathione levels and VEGF secretion. Invest Ophthalmol Vis Sci. 2010;51:4437-46 pubmed publisher
    ..These profound effects clearly demonstrate that maintenance of a specific H:L ratio is part of a basic cellular homeostatic mechanism...
  2. Ray P, Huang B, Tsuji Y. Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling. Cell Signal. 2012;24:981-90 pubmed publisher