Experts and Doctors on spin labels in Ithaca, New York, United States

Summary

Locale: Ithaca, New York, United States
Topic: spin labels

Top Publications

  1. Liang Z, Crepeau R, Freed J. Effects of finite pulse width on two-dimensional Fourier transform electron spin resonance. J Magn Reson. 2005;177:247-60 pubmed
    ..Examples are given for different motional regimes, which show how 2D-ELDOR spectra are affected by the finite pulse widths. The theory shows good agreement with 2D-ELDOR experiments performed as a function of pulse width. ..
  2. Borbat P, Freed J. Measuring distances by pulsed dipolar ESR spectroscopy: spin-labeled histidine kinases. Methods Enzymol. 2007;423:52-116 pubmed
  3. Borbat P, Surendhran K, Bortolus M, Zou P, Freed J, McHaourab H. Conformational motion of the ABC transporter MsbA induced by ATP hydrolysis. PLoS Biol. 2007;5:e271 pubmed
    ..Our results suggest that ATP-powered transport entails LPS sequestering into the open cytoplasmic chamber prior to its translocation by alternating access of the chamber, made possible by 10-20-A conformational changes...
  4. Georgieva E, Roy A, Grigoryants V, Borbat P, Earle K, Scholes C, et al. Effect of freezing conditions on distances and their distributions derived from Double Electron Electron Resonance (DEER): a study of doubly-spin-labeled T4 lysozyme. J Magn Reson. 2012;216:69-77 pubmed publisher
    ..The assignment of bimodal distributions to tether rotamers as opposed to protein conformations is aided by comparing results using MTSL and 4-Bromo MTSL spin-labels. The latter usually produce narrower distance distributions. ..
  5. Georgieva E, Borbat P, Ginter C, Freed J, Boudker O. Conformational ensemble of the sodium-coupled aspartate transporter. Nat Struct Mol Biol. 2013;20:215-21 pubmed publisher
    ..On average, the distributions varied only modestly in detergent and in bilayers, but in several mutants unique conformations were stabilized by the latter. ..

Detail Information

Publications5

  1. Liang Z, Crepeau R, Freed J. Effects of finite pulse width on two-dimensional Fourier transform electron spin resonance. J Magn Reson. 2005;177:247-60 pubmed
    ..Examples are given for different motional regimes, which show how 2D-ELDOR spectra are affected by the finite pulse widths. The theory shows good agreement with 2D-ELDOR experiments performed as a function of pulse width. ..
  2. Borbat P, Freed J. Measuring distances by pulsed dipolar ESR spectroscopy: spin-labeled histidine kinases. Methods Enzymol. 2007;423:52-116 pubmed
  3. Borbat P, Surendhran K, Bortolus M, Zou P, Freed J, McHaourab H. Conformational motion of the ABC transporter MsbA induced by ATP hydrolysis. PLoS Biol. 2007;5:e271 pubmed
    ..Our results suggest that ATP-powered transport entails LPS sequestering into the open cytoplasmic chamber prior to its translocation by alternating access of the chamber, made possible by 10-20-A conformational changes...
  4. Georgieva E, Roy A, Grigoryants V, Borbat P, Earle K, Scholes C, et al. Effect of freezing conditions on distances and their distributions derived from Double Electron Electron Resonance (DEER): a study of doubly-spin-labeled T4 lysozyme. J Magn Reson. 2012;216:69-77 pubmed publisher
    ..The assignment of bimodal distributions to tether rotamers as opposed to protein conformations is aided by comparing results using MTSL and 4-Bromo MTSL spin-labels. The latter usually produce narrower distance distributions. ..
  5. Georgieva E, Borbat P, Ginter C, Freed J, Boudker O. Conformational ensemble of the sodium-coupled aspartate transporter. Nat Struct Mol Biol. 2013;20:215-21 pubmed publisher
    ..On average, the distributions varied only modestly in detergent and in bilayers, but in several mutants unique conformations were stabilized by the latter. ..