Experts and Doctors on solutions in Piscataway, New Jersey, United States


Locale: Piscataway, New Jersey, United States
Topic: solutions

Top Publications

  1. Aramini J, Ma L, Zhou L, Schauder C, Hamilton K, Amer B, et al. Dimer interface of the effector domain of non-structural protein 1 from influenza A virus: an interface with multiple functions. J Biol Chem. 2011;286:26050-60 pubmed publisher
  2. Deboer E, Rasin M. Nucleoside analog labeling of neural stem cells and their progeny. Methods Mol Biol. 2013;1018:21-37 pubmed publisher
    ..The methodology in this chapter covers the classic uses for analog pulse labeling as well as their use in conjunction with the newly characterized technique of in utero electroporation (IUE). ..
  3. Aramini J, Petrey D, Lee D, Janjua H, Xiao R, Acton T, et al. Solution NMR structure of Alr2454 from Nostoc sp. PCC 7120, the first structural representative of Pfam domain family PF11267. J Struct Funct Genomics. 2012;13:171-6 pubmed publisher
    ..PCC 7120, which constitutes the first structural representative from this conserved protein domain family. The structure of Nostoc sp. Alr2454 adopts a novel protein fold. ..
  4. Ouimet M, Griffin J, Carbone Howell A, Wu W, Stebbins N, Di R, et al. Biodegradable ferulic acid-containing poly(anhydride-ester): degradation products with controlled release and sustained antioxidant activity. Biomacromolecules. 2013;14:854-61 pubmed publisher
    ..This renders the polymer a potential candidate for use as a controlled release system for skin care formulations. ..
  5. Suchanek W, Shuk P, Byrappa K, Riman R, TenHuisen K, Janas V. Mechanochemical-hydrothermal synthesis of carbonated apatite powders at room temperature. Biomaterials. 2002;23:699-710 pubmed
    ..The synthesized carbonated apatite powders exhibit chemical compositions and crystallinities similar to those of mineral constituents of hard tissues and therefore are promising for fabrication of bone-resembling implants. ..
  6. Aramini J, Sharma S, Huang Y, Swapna G, Ho C, Shetty K, et al. Solution NMR structure of the SOS response protein YnzC from Bacillus subtilis. Proteins. 2008;72:526-30 pubmed publisher
  7. Zheng D, Aramini J, Montelione G. Validation of helical tilt angles in the solution NMR structure of the Z domain of Staphylococcal protein A by combined analysis of residual dipolar coupling and NOE data. Protein Sci. 2004;13:549-54 pubmed
    ..We propose that this high-accuracy structure of the Z domain of SpA is a more suitable target for theoretical predictions of the free domain structure than previously published lower-accuracy structures of protein A domains. ..
  8. Kapanidis A, Ebright Y, Ludescher R, Chan S, Ebright R. Mean DNA bend angle and distribution of DNA bend angles in the CAP-DNA complex in solution. J Mol Biol. 2001;312:453-68 pubmed
    ..The methods used here will permit mutational analysis of CAP-induced DNA bending and the role of CAP-induced DNA bending in transcriptional activation. ..
  9. Sanders M, Kon C. Glutamine and glutamate metabolism in normal and heat shock conditions in Drosophila Kc cells: conditions supporting glutamine synthesis maximize heat shock polypeptide expression. J Cell Physiol. 1992;150:620-31 pubmed
    ..We conclude that glutamine imposes regulatory changes which alter nitrogen metabolism and support hsp expression in Kc cells...

More Information


  1. Wang Y, Biradar A, Wang G, Sharma K, Duncan C, Rangan S, et al. Controlled synthesis of water-dispersible faceted crystalline copper nanoparticles and their catalytic properties. Chemistry. 2010;16:10735-43 pubmed publisher
  2. Bachhawat P, Swapna G, Montelione G, Stock A. Mechanism of activation for transcription factor PhoB suggested by different modes of dimerization in the inactive and active states. Structure. 2005;13:1353-63 pubmed
  3. Belcher D, Banerjee U, Baehr C, Richardson K, Cabrales P, Berthiaume F, et al. Mixtures of tense and relaxed state polymerized human hemoglobin regulate oxygen affinity and tissue construct oxygenation. PLoS ONE. 2017;12:e0185988 pubmed publisher
    ..These results show the effect of varying the T/R-state PolyhHb mole fraction on oxygenation of tissue-engineered constructs and their potential to oxygenate tissues...
  4. Rai V, Tan H, Michniak Kohn B. Effect of surfactants and pH on naltrexone (NTX) permeation across buccal mucosa. Int J Pharm. 2011;411:92-7 pubmed publisher
  5. Schmeltzer R, Johnson M, Griffin J, Uhrich K. Comparison of salicylate-based poly(anhydride-esters) formed via melt-condensation versus solution polymerization. J Biomater Sci Polym Ed. 2008;19:1295-306 pubmed publisher
    ..The salicylate-based poly(anhydride-esters) undergo a thermodynamic rearrangement during melt-condensation polymerization that is not observed for solution polymerization...
  6. Aramini J, Rossi P, Huang Y, Zhao L, Jiang M, Maglaqui M, et al. Solution NMR structure of the NlpC/P60 domain of lipoprotein Spr from Escherichia coli: structural evidence for a novel cysteine peptidase catalytic triad. Biochemistry. 2008;47:9715-7 pubmed publisher
  7. Minko T, Batrakova E, Li S, Li Y, Pakunlu R, Alakhov V, et al. Pluronic block copolymers alter apoptotic signal transduction of doxorubicin in drug-resistant cancer cells. J Control Release. 2005;105:269-78 pubmed
    ..This is likely to result in the stronger cytotoxic response of the resistant cells to the Dox/P85 formulation compared to the free drug. ..
  8. Volker J, Klump H, Manning G, Breslauer K. Counterion association with native and denatured nucleic acids: an experimental approach. J Mol Biol. 2001;310:1011-25 pubmed
    ..We discuss some of the broader implications of these measurements/results in terms of nucleic acid melting in multicomponent systems, in terms of probing counterion environments, and in terms of potential regulatory mechanisms. ..
  9. Feng W, Tejero R, Zimmerman D, Inouye M, Montelione G. Solution NMR structure and backbone dynamics of the major cold-shock protein (CspA) from Escherichia coli: evidence for conformational dynamics in the single-stranded RNA-binding site. Biochemistry. 1998;37:10881-96 pubmed publisher
    ..88 +/- 0.04 ns and provide evidence for fast time scale (taue < 500 ps) dynamics in surface loops and motions on the microsecond to millisecond time scale within the proposed nucleic acid-binding epitope...
  10. Newkirk K, Feng W, Jiang W, Tejero R, Emerson S, Inouye M, et al. Solution NMR structure of the major cold shock protein (CspA) from Escherichia coli: identification of a binding epitope for DNA. Proc Natl Acad Sci U S A. 1994;91:5114-8 pubmed
    ..These isotope-edited pulsed-field gradient NMR data provide a low-resolution mapping of a DNA-binding epitope on CspA...
  11. Montelione G, Wuthrich K, Burgess A, Nice E, Wagner G, Gibson K, et al. Solution structure of murine epidermal growth factor determined by NMR spectroscopy and refined by energy minimization with restraints. Biochemistry. 1992;31:236-49 pubmed
  12. March P, Gonzalez M. Characterization of the biochemical properties of recombinant ribonuclease III. Nucleic Acids Res. 1990;18:3293-8 pubmed
    ..We postulate that the RNase III dimer undergoes a dramatic conformational change upon recognition of RNA which we are able to trap by cross-linking. ..