Experts and Doctors on carrier proteins in Staten Island, New York, United States

Summary

Locale: Staten Island, New York, United States
Topic: carrier proteins

Top Publications

  1. Yang S, He X, Styles J, Luo M, Schulz H, Elzinga M. Primary structure of the large subunit of trifunctional beta-oxidation complex from pig heart mitochondria. Biochem Biophys Res Commun. 1994;198:431-7 pubmed
  2. Ziemnicka Kotula D, Xu J, Gu H, Potempska A, Kim K, Jenkins E, et al. Identification of a candidate human spectrin Src homology 3 domain-binding protein suggests a general mechanism of association of tyrosine kinases with the spectrin-based membrane skeleton. J Biol Chem. 1998;273:13681-92 pubmed
    ..Based on the conservation of the spectrin SH3 binding site within members of this protein family and published interactions, a general mechanism of interactions of tyrosine kinases with the spectrin-based membrane skeleton is proposed. ..
  3. Frackowiak J, Mazur Kolecka B, Kaczmarski W, Dickson D. Deposition of Alzheimer's vascular amyloid-beta is associated with decreased expression of brain L-3-hydroxyacyl-coenzyme A dehydrogenase (ERAB). Brain Res. 2001;907:44-53 pubmed
    ..Explanation of the association between low levels of HADH and deposition of Abeta by brain smooth muscle cells requires further studies. ..
  4. Murakami N, Bolton D, Hwang Y. Dyrk1A binds to multiple endocytic proteins required for formation of clathrin-coated vesicles. Biochemistry. 2009;48:9297-305 pubmed publisher
    ..Multiple proteins apparently distinctive from the known substrates were phosphorylated in the brain CCV. Our findings suggest a role for Dyrk1A in controlling synaptic vesicle recycling processes. ..
  5. Wang X, Blanchard J, Kohlbrenner E, Clement N, Linden R, Radu A, et al. The carboxy-terminal fragment of inhibitor-2 of protein phosphatase-2A induces Alzheimer disease pathology and cognitive impairment. FASEB J. 2010;24:4420-32 pubmed publisher
    ..These findings suggest a novel etiopathogenic mechanism of AD, which is initiated by the cleavage of I(2)(PP2A), producing I(2CTF), and describe a novel disease-relevant nontransgenic animal model of AD. ..
  6. Xu J, Ziemnicka D, Merz G, Kotula L. Human spectrin Src homology 3 domain binding protein 1 regulates macropinocytosis in NIH 3T3 cells. J Cell Sci. 2000;113 Pt 21:3805-14 pubmed
    ..In the macropinosomes of NIH 3T3 cells, Hssh3bp1 associates with a 200-kDa protein that crossreacts with a monoclonal antibody to the erythroid alpha-spectrin SH3 domain. Thus macropinosomes in cells may contain a spectrin-like protein. ..
  7. Chen Hwang M, Chen H, Elzinga M, Hwang Y. Dynamin is a minibrain kinase/dual specificity Yak1-related kinase 1A substrate. J Biol Chem. 2002;277:17597-604 pubmed
    ..The interactions of dynamin with amphiphysin and endophilin are essential for the formation of endocytic complexes; our results suggest that Mnbk/Dyrk1A may function as a regulator controlling the assembly of endocytic apparatus. ..

Detail Information

Publications7

  1. Yang S, He X, Styles J, Luo M, Schulz H, Elzinga M. Primary structure of the large subunit of trifunctional beta-oxidation complex from pig heart mitochondria. Biochem Biophys Res Commun. 1994;198:431-7 pubmed
  2. Ziemnicka Kotula D, Xu J, Gu H, Potempska A, Kim K, Jenkins E, et al. Identification of a candidate human spectrin Src homology 3 domain-binding protein suggests a general mechanism of association of tyrosine kinases with the spectrin-based membrane skeleton. J Biol Chem. 1998;273:13681-92 pubmed
    ..Based on the conservation of the spectrin SH3 binding site within members of this protein family and published interactions, a general mechanism of interactions of tyrosine kinases with the spectrin-based membrane skeleton is proposed. ..
  3. Frackowiak J, Mazur Kolecka B, Kaczmarski W, Dickson D. Deposition of Alzheimer's vascular amyloid-beta is associated with decreased expression of brain L-3-hydroxyacyl-coenzyme A dehydrogenase (ERAB). Brain Res. 2001;907:44-53 pubmed
    ..Explanation of the association between low levels of HADH and deposition of Abeta by brain smooth muscle cells requires further studies. ..
  4. Murakami N, Bolton D, Hwang Y. Dyrk1A binds to multiple endocytic proteins required for formation of clathrin-coated vesicles. Biochemistry. 2009;48:9297-305 pubmed publisher
    ..Multiple proteins apparently distinctive from the known substrates were phosphorylated in the brain CCV. Our findings suggest a role for Dyrk1A in controlling synaptic vesicle recycling processes. ..
  5. Wang X, Blanchard J, Kohlbrenner E, Clement N, Linden R, Radu A, et al. The carboxy-terminal fragment of inhibitor-2 of protein phosphatase-2A induces Alzheimer disease pathology and cognitive impairment. FASEB J. 2010;24:4420-32 pubmed publisher
    ..These findings suggest a novel etiopathogenic mechanism of AD, which is initiated by the cleavage of I(2)(PP2A), producing I(2CTF), and describe a novel disease-relevant nontransgenic animal model of AD. ..
  6. Xu J, Ziemnicka D, Merz G, Kotula L. Human spectrin Src homology 3 domain binding protein 1 regulates macropinocytosis in NIH 3T3 cells. J Cell Sci. 2000;113 Pt 21:3805-14 pubmed
    ..In the macropinosomes of NIH 3T3 cells, Hssh3bp1 associates with a 200-kDa protein that crossreacts with a monoclonal antibody to the erythroid alpha-spectrin SH3 domain. Thus macropinosomes in cells may contain a spectrin-like protein. ..
  7. Chen Hwang M, Chen H, Elzinga M, Hwang Y. Dynamin is a minibrain kinase/dual specificity Yak1-related kinase 1A substrate. J Biol Chem. 2002;277:17597-604 pubmed
    ..The interactions of dynamin with amphiphysin and endophilin are essential for the formation of endocytic complexes; our results suggest that Mnbk/Dyrk1A may function as a regulator controlling the assembly of endocytic apparatus. ..