Experts and Doctors on zebrafish in St Louis, Missouri, United States

Summary

Locale: St Louis, Missouri, United States
Topic: zebrafish

Top Publications

  1. Schroeter E, Wong R, Gregg R. In vivo development of retinal ON-bipolar cell axonal terminals visualized in nyx::MYFP transgenic zebrafish. Vis Neurosci. 2006;23:833-43 pubmed
    ..Our observations represent the first in vivo visualization of axonal development of bipolar cells in a vertebrate retina. ..
  2. Barbazuk W, Korf I, Kadavi C, Heyen J, Tate S, Wun E, et al. The syntenic relationship of the zebrafish and human genomes. Genome Res. 2000;10:1351-8 pubmed
    ..This work now provides a syntenic relationship to the human genome for the majority of the zebrafish genome. ..
  3. Cox J, Kucenas S, Voigt M. Molecular characterization and embryonic expression of the family of N-methyl-D-aspartate receptor subunit genes in the zebrafish. Dev Dyn. 2005;234:756-66 pubmed
    ..2 is only found in the retina. Our findings demonstrate that the zebrafish can serve as a useful model system for investigating the role of NMDA receptors in the development of the nervous system. ..
  4. Ray W, Bain G, Yao M, Gottlieb D. CYP26, a novel mammalian cytochrome P450, is induced by retinoic acid and defines a new family. J Biol Chem. 1997;272:18702-8 pubmed
    ..Thus, we report the cloning of a member of a novel cytochrome P450 family that is expressed in mammalian embryos and in brain and is induced by RA in the liver. ..
  5. Mendelsohn B, Yin C, Johnson S, Wilm T, Solnica Krezel L, Gitlin J. Atp7a determines a hierarchy of copper metabolism essential for notochord development. Cell Metab. 2006;4:155-62 pubmed
    ..Our data provide insight into the developmental pathophysiology of copper metabolism and suggest that suboptimal copper metabolism may contribute to birth defects. ..
  6. Mayden R, Tang K, Conway K, Freyhof J, Chamberlain S, Haskins M, et al. Phylogenetic relationships of Danio within the order Cypriniformes: a framework for comparative and evolutionary studies of a model species. J Exp Zool B Mol Dev Evol. 2007;308:642-54 pubmed publisher
    ..Danio rerio is sister to D. kyathit among the species of Danio evaluated in this analysis. Microrasbora and Rasbora are non-monophyletic assemblages; however, Boraras is monophyletic...
  7. Venkatesh B, Lee A, Ravi V, Maurya A, Lian M, Swann J, et al. Elephant shark genome provides unique insights into gnathostome evolution. Nature. 2014;505:174-9 pubmed publisher
    ..It thus presents a new model for understanding the origin of adaptive immunity. ..
  8. Higdon C, Mitra R, Johnson S. Gene expression analysis of zebrafish melanocytes, iridophores, and retinal pigmented epithelium reveals indicators of biological function and developmental origin. PLoS ONE. 2013;8:e67801 pubmed publisher
  9. Stark B, Cooper J. Differential expression of CARMIL-family genes during zebrafish development. Cytoskeleton (Hoboken). 2015;72:534-41 pubmed publisher
    ..These results provide new tools and offer insight into understanding the role of the regulation of actin assembly dynamics during embryonic development and tissue morphogenesis. ..

More Information

Publications18

  1. Perathoner S, Daane J, Henrion U, Seebohm G, Higdon C, Johnson S, et al. Bioelectric signaling regulates size in zebrafish fins. PLoS Genet. 2014;10:e1004080 pubmed publisher
    ..Our results provide evidence for a role of bioelectric signaling through K(+) channels in the regulation of allometric scaling and coordination of growth in the zebrafish. ..
  2. Tryon R, Higdon C, Johnson S. Lineage relationship of direct-developing melanocytes and melanocyte stem cells in the zebrafish. PLoS ONE. 2011;6:e21010 pubmed publisher
    ..Thus, the dual strategies of direct-development and MSC-derived development are established in the early gastrula, via fate segregation of the two lineages...
  3. Oppedal D, Goldsmith M. A chemical screen to identify novel inhibitors of fin regeneration in zebrafish. Zebrafish. 2010;7:53-60 pubmed publisher
    ..These studies demonstrate that chemical screening is feasible in adult zebrafish and that it is a reasonable strategy to use for exploring the biology of regeneration. ..
  4. Jensen P, Gunter L, Carayannopoulos M. Akt2 modulates glucose availability and downstream apoptotic pathways during development. J Biol Chem. 2010;285:17673-80 pubmed publisher
  5. Gansner J, Gitlin J. Essential role for the alpha 1 chain of type VIII collagen in zebrafish notochord formation. Dev Dyn. 2008;237:3715-26 pubmed publisher
  6. Gansner J, Madsen E, Mecham R, Gitlin J. Essential role for fibrillin-2 in zebrafish notochord and vascular morphogenesis. Dev Dyn. 2008;237:2844-61 pubmed publisher
    ..Taken together, the data reveal a genetic interaction between fibrillin-2 and the lysyl oxidases in notochord formation and demonstrate the importance of fibrillin-2 in specific early developmental processes in zebrafish...
  7. Mendelsohn B, Kassebaum B, Gitlin J. The zebrafish embryo as a dynamic model of anoxia tolerance. Dev Dyn. 2008;237:1780-8 pubmed publisher
    ..These observations permit mechanistic insight into energy homeostasis during development that now enable genetic and small molecule screens in this vertebrate model of anoxia tolerance. ..
  8. Gansner J, Mendelsohn B, Hultman K, Johnson S, Gitlin J. Essential role of lysyl oxidases in notochord development. Dev Biol. 2007;307:202-13 pubmed
    ..They also provide insight into specific genetic and nutritional factors that may play a role in the pathogenesis of structural birth defects of the axial skeleton. ..
  9. Jensen P, Gitlin J, Carayannopoulos M. GLUT1 deficiency links nutrient availability and apoptosis during embryonic development. J Biol Chem. 2006;281:13382-7 pubmed