Experts and Doctors on yellow fever virus in St Louis, Missouri, United States


Locale: St Louis, Missouri, United States
Topic: yellow fever virus

Top Publications

  1. Droll D, Krishna Murthy H, Chambers T. Yellow fever virus NS2B-NS3 protease: charged-to-alanine mutagenesis and deletion analysis define regions important for protease complex formation and function. Virology. 2000;275:335-47 pubmed publisher
    ..A role for the putative transmembrane regions of NS2B in targeting of NS3 to intracellular membranes is also suggested...
  2. Amberg S, Nestorowicz A, McCourt D, Rice C. NS2B-3 proteinase-mediated processing in the yellow fever virus structural region: in vitro and in vivo studies. J Virol. 1994;68:3794-802 pubmed
    ..This suggests that signalase-mediated cleavage in the lumen of the endoplasmic reticulum may be dependent on prior cleavage at the anchC dibasic site. Possible pathways for processing in the C-prM region are outlined and discussed...
  3. Lindenbach B, Rice C. Genetic interaction of flavivirus nonstructural proteins NS1 and NS4A as a determinant of replicase function. J Virol. 1999;73:4611-21 pubmed
    ..These findings suggest a potential mechanism for integrating NS1 into the cytoplasmic process of RNA replication...
  4. Chambers T, Nickells M. Neuroadapted yellow fever virus 17D: genetic and biological characterization of a highly mouse-neurovirulent virus and its infectious molecular clone. J Virol. 2001;75:10912-22 pubmed
    ..The determinants affect replication efficiency in both neural and extraneural tissues of the mouse and confer some limited host-range differences in cultured cells of nonmurine origin. ..
  5. Vlaycheva L, Chambers T. Neuroblastoma cell-adapted yellow fever 17D virus: characterization of a viral variant associated with persistent infection and decreased virus spread. J Virol. 2002;76:6172-84 pubmed
    ..However, the phenotypic changes which occur in the virus as a result of the persistent infection in vitro do not correlate with attenuation during pathogenesis in the mouse central nervous system. ..
  6. Chambers T, Nestorowicz A, Mason P, Rice C. Yellow fever/Japanese encephalitis chimeric viruses: construction and biological properties. J Virol. 1999;73:3095-101 pubmed