Experts and Doctors on genetic databases in Detroit, Michigan, United States
Locale: Detroit, Michigan, United States
Topic: genetic databases
Wali A, Morin P, Hough C, Lonardo F, Seya T, Carbone M, et al
. Identification of intelectin overexpression in malignant pleural mesothelioma by serial analysis of gene expression (SAGE). Lung Cancer. 2005;48:19-29 pubmed
..Intelectin overexpression in mesothelioma could have potential screening, and therapeutic implications. ..
Pacifico S, Liu G, Guest S, Parrish J, Fotouhi F, Finley R. A database and tool, IM Browser, for exploring and integrating emerging gene and protein interaction data for Drosophila. BMC Bioinformatics. 2006;7:195 pubmed
..By providing access to all of the available information from a variety of data types, the program will also facilitate advanced computational analyses. ..
Hudder A, Novak R. miRNAs: effectors of environmental influences on gene expression and disease. Toxicol Sci. 2008;103:228-40 pubmed publisher
..The role of miRNAs in signal transduction and cellular stress is reviewed. Lastly, we identify new exciting avenues of research on the role of miRNAs in toxicogenomics and the possibility of epigenetic effects on gene expression. ..
Yu J, Pacifico S, Liu G, Finley R. DroID: the Drosophila Interactions Database, a comprehensive resource for annotated gene and protein interactions. BMC Genomics. 2008;9:461 pubmed publisher
..DroID is available at http://www.droidb.org. ..
Tarca A, Draghici S, Khatri P, Hassan S, Mittal P, Kim J, et al
. A novel signaling pathway impact analysis. Bioinformatics. 2009;25:75-82 pubmed publisher
..The results obtained on these data show that SPIA has better specificity and more sensitivity than several widely used pathway analysis methods. SPIA was implemented as an R package available at http://vortex.cs.wayne.edu/ontoexpress/ ..
Lenk G, Tromp G, Weinsheimer S, Gatalica Z, Berguer R, Kuivaniemi H. Whole genome expression profiling reveals a significant role for immune function in human abdominal aortic aneurysms. BMC Genomics. 2007;8:237 pubmed
..The data provide valuable insight for future studies to dissect the pathogenesis of human AAA. These pathways might also be used as targets for the development of therapeutic agents for AAA. ..
Done B, Khatri P, Done A, Draghici S. Predicting novel human gene ontology annotations using semantic analysis. IEEE/ACM Trans Comput Biol Bioinform. 2010;7:91-9 pubmed publisher
..For the remaining 10 percent, we did not find any relevant publications to confirm or contradict the predictions. The n2tn weighting scheme also outperformed the simple binary scheme used in our previous approach. ..