Experts and Doctors on animals in East Lansing, Michigan, United States

Summary

Locale: East Lansing, Michigan, United States
Topic: animals

Top Publications

  1. Lewis D, Farr C, Farquhar A, Kaguni L. Sequence, organization, and evolution of the A+T region of Drosophila melanogaster mitochondrial DNA. Mol Biol Evol. 1994;11:523-38 pubmed
    ..We also propose that the 300-bp conserved DNA sequence element, in conjunction with another primary sequence determinant, perhaps the adjacent thymidylate stretch, functions in the regulation of mitochondrial DNA replication. ..
  2. Dow M, Bakke L, Cassar C, Peters M, Pursley J, Smith G. Gonadotrophin surge-induced upregulation of mRNA for plasminogen activator inhibitors 1 and 2 within bovine periovulatory follicular and luteal tissue. Reproduction. 2002;123:711-9 pubmed
    ..Regulation of PAI-1 and PAI-2 may help to control plasminogen activator activity associated with ovulation and early corpus luteum formation. ..
  3. Ni W, Li M, Thakali K, Fink G, Watts S. The fenfluramine metabolite (+)-norfenfluramine is vasoactive. J Pharmacol Exp Ther. 2004;309:845-52 pubmed
    ..v.) but not prazosin (0.2 mg/kg i.v.). Our findings demonstrate for the first time that (+)-norfenfluramine is vasoactive and has the potential to increase blood pressure...
  4. Ren J, Galligan J. Dynamics of fast synaptic excitation during trains of stimulation in myenteric neurons of guinea-pig ileum. Auton Neurosci. 2005;117:67-78 pubmed
    ..Synaptic rundown is likely due to depletion of a readily releasable pool (RRP) of neurotransmitter. ..
  5. Pérez Rivera A, Fink G, Galligan J. Alpha-1B adrenoceptors mediate neurogenic constriction in mesenteric arteries of normotensive and DOCA-salt hypertensive mice. Auton Neurosci. 2005;121:64-73 pubmed
    ..Nerve-released NE acts primarily at alpha1B-and to a lesser extent at alpha1A-ARs in SHAM arteries whereas NE mediates neurogenic constrictions in DOCA-salt arteries by acting at alpha1B-ARs. ..
  6. Tsao J. Reviewing molecular adaptations of Lyme borreliosis spirochetes in the context of reproductive fitness in natural transmission cycles. Vet Res. 2009;40:36 pubmed publisher
    ..This holistic system approach may help researchers develop additional testable hypotheses about transmission processes, interpret laboratory results, and guide development of future LB control measures and management. ..
  7. Kumar K, White B, Krause G, Indrieri R, Evans A, Hoehner T, et al. A quantitative morphological assessment of the effect of lidoflazine and deferoxamine therapy on global brain ischaemia. Neurol Res. 1988;10:136-40 pubmed
  8. Verbrugge L, Giesy J, Verbrugge D, Woodin B, Stegeman J. Catalytic and immunochemical properties of hepatic cytochrome P450 1A in three avian species treated with beta-naphthoflavone or isosafrole. Comp Biochem Physiol C Toxicol Pharmacol. 2001;130:67-83 pubmed
    ..Variations in responses among avian species indicate that CYP1A proteins and substrate specificities should be characterized for each species used in PHAH biomonitoring programs. ..
  9. Chung Y, Jarvis B, Pestka J. Modulation of lipopolysaccharide-induced proinflammatory cytokine production by satratoxins and other macrocyclic trichothecenes in the murine macrophage. J Toxicol Environ Health A. 2003;66:379-91 pubmed
    ..The capacity of satratoxins and other macrocyclic trichothecenes to alter cytokine production may play an etiologic role in outbreaks of Stachybotrys-associated human illnesses. ..

More Information

Publications484 found, 100 shown here

  1. Herrera F, Triezenberg S. VP16-dependent association of chromatin-modifying coactivators and underrepresentation of histones at immediate-early gene promoters during herpes simplex virus infection. J Virol. 2004;78:9689-96 pubmed
    ..Thus, the VP16 activation domain is responsible for recruiting general transcription factors and coactivators to IE promoters and also for dramatically reducing the association of histones with those promoters. ..
  2. Watson R, Curtin G, Hellmann G, Doolittle D, Goodman J. Increased DNA methylation in the HoxA5 promoter region correlates with decreased expression of the gene during tumor promotion. Mol Carcinog. 2004;41:54-66 pubmed
    ..These data suggest that increased DNA methylation contributes to the downregulation of HoxA5, and combined with hypermethylation of p16 or MGMT, this might facilitate the clonal expansion of increasingly aberrant cells during promotion. ..
  3. Tai M, Chang C, Kiupel M, Webster J, Olson L, Trosko J. Oct4 expression in adult human stem cells: evidence in support of the stem cell theory of carcinogenesis. Carcinogenesis. 2005;26:495-502 pubmed
    ..Oct4 is expressed in a few cells found in the basal layer of human skin epidermis. The data demonstrate that adult stem cells maintain expression of Oct4, consistent with the stem cell hypothesis of carcinogenesis. ..
  4. Rossano M, Schott H, Kaneene J, Murphy A, Kruttlin E, Hines M, et al. Effect of daily administration of pyrantel tartrate in preventing infection in horses experimentally challenged with Sarcocystis neurona. Am J Vet Res. 2005;66:846-52 pubmed
    ..To determine whether daily administration of pyrantel tartrate can prevent infection in horses experimentally challenged with Sarcocystis neurona...
  5. Loniewski K, Patial S, Parameswaran N. Sensitivity of TLR4- and -7-induced NF kappa B1 p105-TPL2-ERK pathway to TNF-receptor-associated-factor-6 revealed by RNAi in mouse macrophages. Mol Immunol. 2007;44:3715-23 pubmed
    ..These results have important implications in terms of therapeutic targeting of TRAF6 complexes in diseases where TLR4 and -7 are involved. ..
  6. Keppie N, Rosenstein D, Holcombe S, Schott H. Objective radiographic assessment of abdominal sand accumulation in horses. Vet Radiol Ultrasound. 2008;49:122-8 pubmed
    ..A score of seven out of 12 was found to have an 83% likelihood of being associated with a positive diagnosis of sand colic. The designed objective scoring method creates a more uniform and accurate method to assess the sand accumulation...
  7. Islam Z, Hegg C, Bae H, Pestka J. Satratoxin G-induced apoptosis in PC-12 neuronal cells is mediated by PKR and caspase independent. Toxicol Sci. 2008;105:142-52 pubmed publisher
    ..Taken together, SG-induced apoptosis in PC-12 neuronal cells is mediated by PKR via a caspase-independent pathway possibly involving AIF translocation. ..
  8. Saini Y, Kim K, Lewandowski R, Bramble L, Harkema J, LaPres J. Role of hypoxia-inducible factor 1{alpha} in modulating cobalt-induced lung inflammation. Am J Physiol Lung Cell Mol Physiol. 2010;298:L139-47 pubmed publisher
    ..The results suggest that epithelial-derived HIF signaling has a critical role in establishing a tissue's inflammatory response, and compromised HIF1alpha signaling biases the tissue towards a Th2-mediated reaction. ..
  9. Carey S, Plopper C, Hyde D, Islam Z, Pestka J, Harkema J. Satratoxin-G from the black mold Stachybotrys chartarum induces rhinitis and apoptosis of olfactory sensory neurons in the nasal airways of rhesus monkeys. Toxicol Pathol. 2012;40:887-98 pubmed publisher
    ..This model provides new insight into the potential risk of nasal airway injury and neurotoxicity caused by exposure to water-damaged buildings. ..
  10. Simkins T, Janis K, McClure A, Behrouz B, Pappas S, LEHNER A, et al. Comparison of the D2 receptor regulation and neurotoxicant susceptibility of nigrostriatal dopamine neurons in wild-type and CB1/CB2 receptor knockout mice. J Neuroimmune Pharmacol. 2012;7:533-8 pubmed publisher
    ..These studies support the use of CB1/CB2 KO mice for investigating the cannabinoid receptor-mediated regulation of the NSDA neuronal system in models of PD. ..
  11. Aldhamen Y, Seregin S, Kousa Y, Rastall D, Appledorn D, Godbehere S, et al. Improved cytotoxic T-lymphocyte immune responses to a tumor antigen by vaccines co-expressing the SLAM-associated adaptor EAT-2. Cancer Gene Ther. 2013;20:564-75 pubmed publisher
  12. Goffredi S, Yi H, Zhang Q, Klann J, Struve I, Vrijenhoek R, et al. Genomic versatility and functional variation between two dominant heterotrophic symbionts of deep-sea Osedax worms. ISME J. 2014;8:908-24 pubmed publisher
  13. Stedtfeld R, Williams M, Fakher U, Johnson T, Stedtfeld T, Wang F, et al. Antimicrobial resistance dashboard application for mapping environmental occurrence and resistant pathogens. FEMS Microbiol Ecol. 2016;92: pubmed publisher
    ..Interested users are invited to download a beta version (available on iOS or Android), submit AR information using the application, and provide feedback on current and prospective functionalities. ..
  14. Cal L, Megias M, Cerdá Reverter J, Postlethwait J, Braasch I, Rotllant J. BAC Recombineering of the Agouti Loci from Spotted Gar and Zebrafish Reveals the Evolutionary Ancestry of Dorsal-Ventral Pigment Asymmetry in Fish. J Exp Zool B Mol Dev Evol. 2017;328:697-708 pubmed publisher
    ..These experiments provide evidence that the mechanism leading to an environmentally important pigment pattern was likely in place before the origin of teleosts. ..
  15. Keller S, Mao Y, Struffi P, Margulies C, Yurk C, Anderson A, et al. dCtBP-dependent and -independent repression activities of the Drosophila Knirps protein. Mol Cell Biol. 2000;20:7247-58 pubmed
    ..These results indicate that Knirps can utilize two different pathways to mediate transcriptional repression and suggest that the phenomenon of short-range repression may be a combination of independent activities. ..
  16. Hashimoto M, Wilson J. Membrane potential-dependent conformational changes in mitochondrially bound hexokinase of brain. Arch Biochem Biophys. 2000;384:163-73 pubmed
    ..These results provide further insight into the role of hexokinase-mitochondrial interactions in regulation of cerebral glucose metabolism. ..
  17. Dloniak S, French J, Holekamp K. Rank-related maternal effects of androgens on behaviour in wild spotted hyaenas. Nature. 2006;440:1190-3 pubmed
    ..They also suggest an organizational mechanism for the development of female dominance and aggressiveness in spotted hyaenas, traits that may offset the costs of extreme virilization...
  18. Linderman M, An L, Bearer S, He G, Ouyang Z, Liu J. Interactive effects of natural and human disturbances on vegetation dynamics across landscapes. Ecol Appl. 2006;16:452-63 pubmed
    ..Our study showed not only the importance of the spatial distribution of direct household impacts on habitat, but also the far-reaching effects of the indirect interactions between humans and the landscapes they are modifying. ..
  19. Fyfe J, Kurzhals R, Hawkins M, Wang P, Yuhki N, Giger U, et al. A complex rearrangement in GBE1 causes both perinatal hypoglycemic collapse and late-juvenile-onset neuromuscular degeneration in glycogen storage disease type IV of Norwegian forest cats. Mol Genet Metab. 2007;90:383-92 pubmed publisher
    ..The molecular characterization of feline GSD IV will enhance further studies of GSD IV pathophysiology and development of novel therapies in this unique animal model...
  20. Thakali K, Galligan J, Fink G, Gariepy C, Watts S. Pharmacological endothelin receptor interaction does not occur in veins from ET(B) receptor deficient rats. Vascul Pharmacol. 2008;49:6-13 pubmed publisher
    ..Our data suggest that pharmacological ET A and ET B receptor interaction may be dependent on the presence of functional ET B receptors and independent of receptor location. ..
  21. Zhong B, Wang D. N-oleoyldopamine, a novel endogenous capsaicin-like lipid, protects the heart against ischemia-reperfusion injury via activation of TRPV1. Am J Physiol Heart Circ Physiol. 2008;295:H728-35 pubmed publisher
    ..The protective effect of OLDA is void in TRPV1(-/-) hearts, supporting the notion that TRPV1 mediates OLDA-induced protection against cardiac I/R injury. ..
  22. Kaplan B, Springs A, Kaminski N. The profile of immune modulation by cannabidiol (CBD) involves deregulation of nuclear factor of activated T cells (NFAT). Biochem Pharmacol. 2008;76:726-37 pubmed publisher
    ..Taken together, these data suggest that CBD suppresses T cell function and that CB1 and/or CB2 play a critical role in the magnitude of the in vitro anti-sRBC IgM AFC response. ..
  23. Hunt H, Fadly A, Silva R, Zhang H. Survey of endogenous virus and TVB* receptor status of commercial chicken stocks supplying specific-pathogen-free eggs. Avian Dis. 2008;52:433-40 pubmed
    ..The implications of these findings for vaccine manufacturers and regulatory agencies are discussed. ..
  24. Geor R, Frank N. Metabolic syndrome-From human organ disease to laminar failure in equids. Vet Immunol Immunopathol. 2009;129:151-4 pubmed publisher
  25. Ahmed E, Zehr J, Schulz K, Lorenz B, Doncarlos L, Sisk C. Pubertal hormones modulate the addition of new cells to sexually dimorphic brain regions. Nat Neurosci. 2008;11:995-7 pubmed
    ..Removing gonadal hormones before puberty eliminates these sex differences, indicating that gonadal steroids direct the addition of new cells during puberty to maintain and accentuate sexual dimorphisms in the adult brain. ..
  26. Shaw P, Ganey P, Roth R. Trovafloxacin enhances the inflammatory response to a Gram-negative or a Gram-positive bacterial stimulus, resulting in neutrophil-dependent liver injury in mice. J Pharmacol Exp Ther. 2009;330:72-8 pubmed publisher
  27. Min J, Farooq M, Greenberg E, Aloka F, Bhatt A, Kassab M, et al. Cardiac dysfunction after left permanent cerebral focal ischemia: the brain and heart connection. Stroke. 2009;40:2560-3 pubmed publisher
    ..Furthermore, mice exhibiting cardiac dysfunction had elevated levels of NE in the serum and heart. ..
  28. North C, Crawford R, Lu H, Kaminski N. Simultaneous in vivo time course and dose response evaluation for TCDD-induced impairment of the LPS-stimulated primary IgM response. Toxicol Sci. 2009;112:123-32 pubmed publisher
    ..The deregulation of Blimp-1 expression by TCDD provides a partial explanation for the concomitant suppression of the IgM response and confirms previous observations established in vitro. ..
  29. Payankaulam S, Arnosti D. Groucho corepressor functions as a cofactor for the Knirps short-range transcriptional repressor. Proc Natl Acad Sci U S A. 2009;106:17314-9 pubmed publisher
  30. Müller T, Meek K, Hausinger R. Human AlkB homologue 1 (ABH1) exhibits DNA lyase activity at abasic sites. DNA Repair (Amst). 2010;9:58-65 pubmed publisher
    ..ABH1 can cleave at closely spaced AP-sites on opposite DNA strands yielding double-strand breaks in vitro and this reaction may relate to the physiological role of this unexpected AP lyase activity. ..
  31. Seregin S, Hartman Z, Appledorn D, Godbehere S, Jiang H, Frank M, et al. Novel adenovirus vectors 'capsid-displaying' a human complement inhibitor. J Innate Immun. 2010;2:353-9 pubmed publisher
    ..In summary, our work has shown that a novel COMPinh-displaying Ad5 has the potential for broadening the safe use of Ad vectors in future human applications. ..
  32. Corl C, Robinson H, Contreras G, Holcombe S, Cook V, Sordillo L. Ethyl pyruvate diminishes the endotoxin-induced inflammatory response of bovine mammary endothelial cells. J Dairy Sci. 2010;93:5188-99 pubmed publisher
    ..Ethyl pyruvate is safe for human consumption, and it may be an attractive candidate as a therapeutic in ameliorating the severe pathogenesis associated with coliform mastitis. ..
  33. Peacor S, Pangle K, Schiesari L, Werner E. Scaling-up anti-predator phenotypic responses of prey: impacts over multiple generations in a complex aquatic community. Proc Biol Sci. 2012;279:122-8 pubmed publisher
    ..Our findings demonstrate that adaptive phenotypic plasticity of individuals can scale-up to affect the structure of ecological communities. ..
  34. Manjarin R, Steibel J, Kirkwood R, Taylor N, Trottier N. Transcript abundance of hormone receptors, mammalian target of rapamycin pathway-related kinases, insulin-like growth factor I, and milk proteins in porcine mammary tissue. J Anim Sci. 2012;90:221-30 pubmed publisher
  35. Watts S, Shaw S, Burnett R, Dorrance A. Indoleamine 2,3-diooxygenase in periaortic fat: mechanisms of inhibition of contraction. Am J Physiol Heart Circ Physiol. 2011;301:H1236-47 pubmed publisher
    ..We conclude that IDO is an enzyme active primarily in brown fat surrounding the thoracic aorta and depresses aortic contractility. ..
  36. Kovalenko P, Basson M. Changes in morphology and function in small intestinal mucosa after Roux-en-Y surgery in a rat model. J Surg Res. 2012;177:63-9 pubmed publisher
  37. Boer J, Mulrooney S, Hausinger R. Nickel-dependent metalloenzymes. Arch Biochem Biophys. 2014;544:142-52 pubmed publisher
    ..Selected other enzymes are active with nickel, but the physiological relevance of this metal specificity is unclear. Additional nickel-containing proteins of undefined function have been identified. ..
  38. Wood T, Cross I. <i>Camptopoeum</i> (<i>Camptopoeum</i>) <i>baldocki</i> spec. nov., a new panurgine bee species from Portugal and a description of the male of <i>Flavipanurgus</i> <i>fuzetus</i> Patiny (And. Zootaxa. 2017;4254:285-293 pubmed publisher
    ..As a genus, Flavipanurgus species appear to be narrowly oligolectic on a range of flowers from the botanical families Caryophyllaceae, Cistaceae and Crassulaceae. ..
  39. Phan H, Sjögren B, Neubig R. Human Missense Mutations in Regulator of G Protein Signaling 2 Affect the Protein Function Through Multiple Mechanisms. Mol Pharmacol. 2017;92:451-458 pubmed publisher
    ..These molecular behaviors can provide insight to inform antihypertensive therapeutics in individuals with variants having reduced function. ..
  40. Ryu J, Olson L, Arnosti D. Cell-type specificity of short-range transcriptional repressors. Proc Natl Acad Sci U S A. 2001;98:12960-5 pubmed
    ..This broad activity indicates that the context of the target gene is not critical for the ability of short-range repressors to block transcription, in contrast to other repressors that act only on stably integrated genes. ..
  41. Hoffmann E, Miller J. Reduction of mosquito (Diptera: Culicidae) attacks on a human subject by combination of wind and vapor-phase DEET repellent. J Med Entomol. 2002;39:935-8 pubmed
    ..6 m/s and the DEET vapor concentration was estimated at 2 microg/liter air. We suggest a combination of directed wind and volatile repellent might be developed as a mosquito deterrent strategy for the backyard setting...
  42. Ryu J, Arnosti D. Functional similarity of Knirps CtBP-dependent and CtBP-independent transcriptional repressor activities. Nucleic Acids Res. 2003;31:4654-62 pubmed
  43. Wade J, Tang Y, Peabody C, Tempelman R. Enhanced gene expression in the forebrain of hatchling and juvenile male zebra finches. J Neurobiol. 2005;64:224-38 pubmed publisher
    ..Thus, we have identified genes likely to be involved in masculinization of the structure and/or function of the song circuit, some of which could be initial triggers for the sexual differentiation process...
  44. Gimeno I, Witter R, Fadly A, Silva R. Novel criteria for the diagnosis of Marek's disease virus-induced lymphomas. Avian Pathol. 2005;34:332-40 pubmed
    ..Other markers studied were not specific for MDV and therefore had limited value for diagnosis. Nonetheless, some of these markers might have potential value in research as they will help to identify transformed cells...
  45. Galligan J, Miller S, Katki K, Supowit S, Dipette D, Fink G. Increased substance P content in nerve fibers associated with mesenteric veins from deoxycorticosterone acetate (DOCA)-salt hypertensive rats. Regul Pept. 2006;133:97-104 pubmed
    ..NK-3 receptors mediate venoconstriction which is unchanged in DOCA-salt hypertension. Increased release of SP from perivenous nerves might contribute to the increased venomotor tone in DOCA-salt hypertension. ..
  46. Brubaker R. Intermediary metabolism, Na+, the low calcium-response, and acute disease. Adv Exp Med Biol. 2007;603:116-29 pubmed
    ..Occurrence of this event in vivo would radically alter the equilibrium of host amino acid pools thereby contributing to enhanced lethality. ..
  47. Dunn J, Reid G, Bruening M. Techniques for phosphopeptide enrichment prior to analysis by mass spectrometry. Mass Spectrom Rev. 2010;29:29-54 pubmed publisher
    ..With recent advances in enrichment techniques in hand, MS analysis should provide important insights into phosphorylation pathways. ..
  48. Obaro S. Pneumococcal infections and sickle cell disease in Africa: does absence of evidence imply evidence of absence?. Arch Dis Child. 2009;94:713-6 pubmed publisher
    ..Research to clearly define the leading cause of infection-related morbidity and mortality in SCD in Africa should be encouraged. ..
  49. Bauer A, Fostel J, Degraff L, Rondini E, Walker C, Grissom S, et al. Transcriptomic analysis of pathways regulated by toll-like receptor 4 in a murine model of chronic pulmonary inflammation and carcinogenesis. Mol Cancer. 2009;8:107 pubmed publisher
    ..g. Cxcl5), chemotaxis (e.g. Ccr1) and other cell proliferation genes (e.g. Arg1, Pthlh). Future studies will determine the utility of these pathways as indicators of immune system deficiencies and tumorigenesis. ..
  50. Mehrotra S, Hunley S, Pawelec K, Zhang L, Lee I, Baek S, et al. Cell adhesive behavior on thin polyelectrolyte multilayers: cells attempt to achieve homeostasis of its adhesion energy. Langmuir. 2010;26:12794-802 pubmed publisher
  51. Mochizuki A, Pace A, Rockwell C, Roth K, Chow A, O Brien K, et al. Hepatic stellate cells orchestrate clearance of necrotic cells in a hypoxia-inducible factor-1?-dependent manner by modulating macrophage phenotype in mice. J Immunol. 2014;192:3847-3857 pubmed publisher
  52. Kong B, Zhu Y, Li G, Williams J, Buckley K, Tawfik O, et al. Mice with hepatocyte-specific FXR deficiency are resistant to spontaneous but susceptible to cholic acid-induced hepatocarcinogenesis. Am J Physiol Gastrointest Liver Physiol. 2016;310:G295-302 pubmed publisher
    ..In conclusion, this study shows that hepatic FXR deficiency may only serve as a tumor initiator, and increased bile acids is required for tumor formation likely by promoting cell proliferation. ..
  53. Hunt H, Pharr G, Bacon L. Molecular analysis reveals MHC class I intra-locus recombination in the chicken. Immunogenetics. 1994;40:370-5 pubmed
  54. Li L, Zhao Y, McCaig B, Wingerd B, Wang J, Whalon M, et al. The tomato homolog of CORONATINE-INSENSITIVE1 is required for the maternal control of seed maturation, jasmonate-signaled defense responses, and glandular trichome development. Plant Cell. 2004;16:126-43 pubmed
    ..These findings indicate that the JA/COI1 signaling pathway regulates distinct developmental processes in different plants and suggest a role for JA in the promotion of glandular trichome-based defenses. ..
  55. Somvanshi V, Viswanathan P, Jacobs J, Mulks M, Sundin G, Ciche T. The type 2 secretion Pseudopilin, gspJ, is required for multihost pathogenicity of Burkholderia cenocepacia AU1054. Infect Immun. 2010;78:4110-21 pubmed publisher
    ..This study highlights strain specific differences in B. cenocepacia virulence mechanisms important for understanding what enables environmental microbes to function as opportunistic pathogens. ..
  56. Teixeira L, Grieshop M, Gut L. Effect of pheromone dispenser density on timing and duration of approaches by peachtree borer. J Chem Ecol. 2010;36:1148-54 pubmed publisher
    ..Shorter approaches to dispensers placed at high density than singly suggest that dispenser retentiveness is not constant with peachtree borer, which may bias estimates of disruption activity as a function of dispenser density. ..
  57. Zhang Y, Arnosti D. Conserved catalytic and C-terminal regulatory domains of the C-terminal binding protein corepressor fine-tune the transcriptional response in development. Mol Cell Biol. 2011;31:375-84 pubmed publisher
    ..Our results indicate that the structural and enzymatic features of CtBP, previously thought to be dispensable for overall transcriptional control, are critical for modulating this protein's activity in diverse developmental settings. ..
  58. Ramanathan G, Atchison W. Ca2+ entry pathways in mouse spinal motor neurons in culture following in vitro exposure to methylmercury. Neurotoxicology. 2011;32:742-50 pubmed publisher
    ..Spinal motor neurons are highly sensitive to this effect of acute exposure to MeHg. ..
  59. Faisal M, Schulz C, Eissa A, Brenden T, Winters A, Whelan G, et al. Epidemiological investigation of Renibacterium salmoninarum in three Oncorhynchus spp. in Michigan from 2001 to 2010. Prev Vet Med. 2012;107:260-74 pubmed publisher
    ..This study provides evidence that enhanced biosecurity measures at culture facilities and collection sites are capable of severely curtailing disease infection in wild populations even at the scale of Lake Michigan fisheries...
  60. Currie R, Peffer R, Goetz A, Omiecinski C, Goodman J. Phenobarbital and propiconazole toxicogenomic profiles in mice show major similarities consistent with the key role that constitutive androstane receptor (CAR) activation plays in their mode of action. Toxicology. 2014;321:80-8 pubmed publisher
  61. Fader K, Nault R, Kirby M, Markous G, Matthews J, Zacharewski T. Convergence of hepcidin deficiency, systemic iron overloading, heme accumulation, and REV-ERBα/β activation in aryl hydrocarbon receptor-elicited hepatotoxicity. Toxicol Appl Pharmacol. 2017;321:1-17 pubmed publisher
    ..Collectively, these results suggest that Hamp repression, Fe accumulation, and increased heme levels converge to promote oxidative stress and the progression of TCDD-elicited hepatotoxicity. ..
  62. Sawyer D, Rech R, Adams T, Durham R, Richter M, Striler E. Analgesia and behavioral responses of dogs given oxymorphone-acepromazine and meperidine-acepromazine after methoxyflurane and halothane anesthesia. Am J Vet Res. 1992;53:1361-8 pubmed
    ..Pulse rate was significantly depressed by the higher doses of OXY following HAL, but was not changed by MEP following either anesthetic.(ABSTRACT TRUNCATED AT 250 WORDS) ..
  63. Fatunmbi O, Reed W. Evaluation of a commercial modified live virus fowl pox vaccine for the control of "variant" fowl poxvirus infections. Avian Dis. 1996;40:582-7 pubmed
    ..The variant isolates tested may be good vaccine candidates to prevent the vaccine breaks currently encountered in previously pox-vaccinated flocks...
  64. Hewitt G, Strunk B, Margulies C, Priputin T, Wang X, Amey R, et al. Transcriptional repression by the Drosophila giant protein: cis element positioning provides an alternative means of interpreting an effector gradient. Development. 1999;126:1201-10 pubmed
    ..We also demonstrate that a chimeric Gal4-Giant protein lacking the basic/zipper domain can specifically repress reporter genes, suggesting that the Giant effector domain is an autonomous repression domain. ..
  65. Refsal K, Provencher Bolliger A, Graham P, Nachreiner R. Update on the diagnosis and treatment of disorders of calcium regulation. Vet Clin North Am Small Anim Pract. 2001;31:1043-62 pubmed
    ..As already emphasized, the foundation of using [table: see text] these assays is first assessing whether the calcium abnormality is of a parathyroid-dependent or parathyroid-independent classification. ..
  66. Vengellur A, Woods B, Ryan H, Johnson R, LaPres J. Gene expression profiling of the hypoxia signaling pathway in hypoxia-inducible factor 1alpha null mouse embryonic fibroblasts. Gene Expr. 2003;11:181-97 pubmed
    ..These results suggest that HIF1alpha is the predominant isoform in fibroblasts and that it regulates a wide battery of genes critical for normal cellular function and survival under various stresses. ..
  67. Sulentic C, Kang J, Na Y, Kaminski N. Interactions at a dioxin responsive element (DRE) and an overlapping kappaB site within the hs4 domain of the 3'alpha immunoglobulin heavy chain enhancer. Toxicology. 2004;200:235-46 pubmed
    ..These results suggest that the AhR nuclear complex and NF-kappaB/Rel proteins converge at the DRE and kappaB motif to influence transcriptional activity of the hs4 enhancer fragment. ..
  68. Eisthen H. The goldfish knows: olfactory receptor cell morphology predicts receptor gene expression. J Comp Neurol. 2004;477:341-6 pubmed
  69. Dillon P, Root Bernstein R, Lieder C. Ascorbate enhancement of H1 histamine receptor sensitivity coincides with ascorbate oxidation inhibition by histamine receptors. Am J Physiol Cell Physiol. 2006;291:C977-84 pubmed
    ..These receptors may play a significant role in maintaining extracellular ascorbate in a reduced state. ..
  70. Tadese T, Fitzgerald S, Reed W. Detection and differentiation of re-emerging fowlpox virus (FWPV) strains carrying integrated reticuloendotheliosis virus (FWPV-REV) by real-time PCR. Vet Microbiol. 2008;127:39-49 pubmed
    ..However, the minor variations found within the short-targeted ENV sequence from FWPV-REV strains suggest that these strains could have either undergone periodic point mutational changes or integration with different REV-ENV subtypes...
  71. Kiyosawa N, Kwekel J, Burgoon L, Williams K, Tashiro C, Chittim B, et al. o,p'-DDT elicits PXR/CAR-, not ER-, mediated responses in the immature ovariectomized rat liver. Toxicol Sci. 2008;101:350-63 pubmed
    ..Based on the species-specific differences in CAR regulation, the extrapolation of rodent DDT hepatocarcinogenicity to humans warrants further investigation. ..
  72. Heidari M, Huebner M, Kireev D, Silva R. Transcriptional profiling of Marek's disease virus genes during cytolytic and latent infection. Virus Genes. 2008;36:383-92 pubmed publisher
  73. Shi Y, Pestka J. Mechanisms for suppression of interleukin-6 expression in peritoneal macrophages from docosahexaenoic acid-fed mice. J Nutr Biochem. 2009;20:358-68 pubmed publisher
    ..These data suggest that DON-induced IL-6 expression is CREB mediated and PKR dependent, and that requisite kinase activities for these pathways were suppressed in macrophages from mice fed DHA for an extended period. ..
  74. Ortiz Colón G, Grant A, Doumit M, Buskirk D. Bovine intramuscular, subcutaneous, and perirenal stromal-vascular cells express similar glucocorticoid receptor isoforms, but exhibit different adipogenic capacity. J Anim Sci. 2009;87:1913-20 pubmed publisher
    ..27). Collectively, these data demonstrate differences in adipogenic activity among bovine i.m., s.c., and p.r. S-V cells, but indicate no relationship between adipogenic activity and glucocorticoid receptor abundance or function. ..
  75. Gregory Bryson E, Bartlett E, Kiupel M, Hayes S, Yuzbasiyan Gurkan V. Canine and human gastrointestinal stromal tumors display similar mutations in c-KIT exon 11. BMC Cancer. 2010;10:559 pubmed publisher
    ..This study further demonstrates that spontaneously occurring canine GISTs share molecular features with human GISTs and are an appropriate model for human GISTs. ..
  76. Henley C, Nunez A, Clemens L. Hormones of choice: the neuroendocrinology of partner preference in animals. Front Neuroendocrinol. 2011;32:146-54 pubmed publisher
    ..Additional paradigms that address these questions are needed for better understanding of partner preferences in rodents. ..
  77. Zhang M, Storm D, Wang H. Bidirectional synaptic plasticity and spatial memory flexibility require Ca2+-stimulated adenylyl cyclases. J Neurosci. 2011;31:10174-83 pubmed publisher
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