Experts and Doctors on helicobacter pylori in Boston, Massachusetts, United States
Locale: Boston, Massachusetts, United States
Topic: helicobacter pylori
Zheng Y, Roberts R, Kasif S. Segmentally variable genes: a new perspective on adaptation. PLoS Biol. 2004;2:E81 pubmed
..Discerning their function and identifying their binding partners may offer biologists new insights into the basic mechanisms of adaptation, context-dependent evolution, and the interaction between microbes and their environment. ..
Hamblin M, Viveiros J, Yang C, Ahmadi A, Ganz R, Tolkoff M. Helicobacter pylori accumulates photoactive porphyrins and is killed by visible light. Antimicrob Agents Chemother. 2005;49:2822-7 pubmed
..Both virulent and drug-resistant strains are killed. The data suggest that phototherapy might be used to treat H. pylori infection in the human stomach. ..
Keates A, Tummala S, Peek R, Csizmadia E, Kunzli B, Becker K, et al
. Helicobacter pylori infection stimulates plasminogen activator inhibitor 1 production by gastric epithelial cells. Infect Immun. 2008;76:3992-9 pubmed publisher
..pylori-mediated PAI-1 upregulation. These findings suggest that the upregulation of PAI-1 in H. pylori-infected gastric epithelial cells may contribute to the carcinogenic process. ..
Wang T, Goldenring J, Dangler C, Ito S, Mueller A, Jeon W, et al
. Mice lacking secretory phospholipase A2 show altered apoptosis and differentiation with Helicobacter felis infection. Gastroenterology. 1998;114:675-89 pubmed
..Because sPLA2 has been identified recently as the MOM1 (modifier of MIN) locus that influences polyp formation in the colon, these studies suggest that sPLA2 may also influence the gastric epithelial response to Helicobacter infection. ..
Chang Y, Kim H, Albacker L, Lee H, Baumgarth N, Akira S, et al
. Influenza infection in suckling mice expands an NKT cell subset that protects against airway hyperreactivity. J Clin Invest. 2011;121:57-69 pubmed publisher
..These findings suggest what we believe to be a novel pathway that can regulate AHR, and a new therapeutic strategy (treatment with glycolipid activators of this NKT cell population) for asthma...