Experts and Doctors on fluorescent antibody technique in Frederick, Maryland, United States
Locale: Frederick, Maryland, United States
Topic: fluorescent antibody technique
Chang C, Newton D, Rybak S, Wlodawer A. Crystallographic and functional studies of a modified form of eosinophil-derived neurotoxin (EDN) with novel biological activities. J Mol Biol. 2002;317:119-30 pubmed
Mazurov D, Heidecker G, Derse D. HTLV-1 Gag protein associates with CD82 tetraspanin microdomains at the plasma membrane. Virology. 2006;346:194-204 pubmed publisher
..Our data suggest that once at the plasma membrane, HTLV-1 virion components associate with CD82-containing microdomains, which may facilitate the mobilization of nascent virions to sites of intercellular adhesion...
Mathews L, Hurt E, Zhang X, Farrar W. Epigenetic regulation of CpG promoter methylation in invasive prostate cancer cells. Mol Cancer. 2010;9:267 pubmed publisher
..These aggressive sub-populations of cells may be linked to the cancer stem cell hypothesis, making their patterns of epigenetic regulation very attractive for biomarker analysis. ..
Yang M, Chaudhary A, Seaman S, Dunty J, Stevens J, Elzarrad M, et al
. The cell surface structure of tumor endothelial marker 8 (TEM8) is regulated by the actin cytoskeleton. Biochim Biophys Acta. 2011;1813:39-49 pubmed publisher
Feng Y, Shen J, Streaker E, Lockwood M, Zhu Z, Low P, et al
. A folate receptor beta-specific human monoclonal antibody recognizes activated macrophage of rheumatoid patients and mediates antibody-dependent cell-mediated cytotoxicity. Arthritis Res Ther. 2011;13:R59 pubmed publisher
..m909 alone has potential to eliminate FR? positive cells. Because m909 does not compete with folate for receptor binding, it can be used with folate-drug conjugates in a combination therapy. m909 can also be a valuable research reagent. ..
Yang G, Obiakor H, Sinha R, Newman B, Hood B, Conrads T, et al
. Activation-induced deaminase cloning, localization, and protein extraction from young VH-mutant rabbit appendix. Proc Natl Acad Sci U S A. 2005;102:17083-8 pubmed publisher
..Although much work remains to understand fully the mechanism of action of AID and its association with other cellular components, the rabbit system now offers a particularly useful model for future studies of these dynamics...
Baba M, Furihata M, Hong S, Tessarollo L, Haines D, Southon E, et al
. Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys. J Natl Cancer Inst. 2008;100:140-54 pubmed publisher
..The conditional BHD knockout mouse may be a useful research model for dissecting multistep kidney carcinogenesis, and rapamycin may be considered as a potential treatment for Birt-Hogg-Dubé syndrome. ..
Crea F, Duhagon Serrat M, Hurt E, Thomas S, Danesi R, Farrar W. BMI1 silencing enhances docetaxel activity and impairs antioxidant response in prostate cancer. Int J Cancer. 2011;128:1946-54 pubmed publisher
..BMI1-controlled antioxidant genes are overexpressed in aggressive PC and should be tested as predictors of chemotherapy failure. ..
Fer N, Shoemaker R, Monks A. Adaphostin toxicity in a sensitive non-small cell lung cancer model is mediated through Nrf2 signaling and heme oxygenase 1. J Exp Clin Cancer Res. 2010;29:91 pubmed publisher