Experts and Doctors on rats in Baton Rouge, Louisiana, United States


Locale: Baton Rouge, Louisiana, United States
Topic: rats

Top Publications

  1. Liu X, York D, Bray G. Regulation of ghrelin gene expression in stomach and feeding response to a ghrelin analogue in two strains of rats. Peptides. 2004;25:2171-7 pubmed
    ..In addition, a differential regulation of ghrelin gene expression between OM and S5B rats may be important in their differential sensitivity to HF diet-induced obesity. ..
  2. Zheng Z, Lewis M, Travagli R. In vitro analysis of the effects of cholecystokinin on rat brain stem motoneurons. Am J Physiol Gastrointest Liver Physiol. 2005;288:G1066-73 pubmed
    ..Our data indicate that CCK-A receptors are present on a subpopulation of gastric-projecting neurons and that their activation leads to excitation of the DMV membrane. ..
  3. Zheng H, Patterson L, Berthoud H. Orexin-A projections to the caudal medulla and orexin-induced c-Fos expression, food intake, and autonomic function. J Comp Neurol. 2005;485:127-42 pubmed
    ..The results confirm that hypothalamomedullary orexin projections are involved in a variety of physiological functions, including ingestive behavior and sympathetic outflow. ..
  4. Luo C, Lu X, Stubbs L, Kim J. Rapid evolution of a recently retroposed transcription factor YY2 in mammalian genomes. Genomics. 2006;87:348-55 pubmed
  5. Liu D, Wise G. Expression of endothelial monocyte-activating polypeptide II in the rat dental follicle and its potential role in tooth eruption. Eur J Oral Sci. 2008;116:334-40 pubmed publisher
  6. Pan W, Yu C, Hsuchou H, Khan R, Kastin A. Cerebral microvascular IL15 is a novel mediator of TNF action. J Neurochem. 2009;111:819-27 pubmed publisher
    ..We conclude that the cerebral microvascular IL15 system is a novel inflammatory mediator that transduces the actions of TNF. ..
  7. Harris R, Zhou J, Youngblood B, Smagin G, Ryan D. Failure to change exploration or saccharin preference in rats exposed to chronic mild stress. Physiol Behav. 1997;63:91-100 pubmed
    ..Saccharin intake of CMS rats was dependent upon their dehydration state and could not be attributed to stress-induced anhedonia. ..
  8. Mastronardi C, Yu W, Srivastava V, Dees W, McCann S. Lipopolysaccharide-induced leptin release is neurally controlled. Proc Natl Acad Sci U S A. 2001;98:14720-5 pubmed
    ..Because alpha-bromoergocryptine decreased basal and LPS-induced leptin release, dopaminergic neurons may inhibit basal and LPS-induced leptin release by suppression of release of prolactin from the adenohypophysis. ..
  9. Primeaux S, York D, Bray G. Neuropeptide Y administration into the amygdala alters high fat food intake. Peptides. 2006;27:1644-51 pubmed
    ..Intra-amygdalar NPY administration did not produce conditioned taste aversions to a novel saccharin solution. These results suggest that amygdalar NPY may have a role in macronutrient selection, without altering total caloric intake. ..

More Information

Publications176 found, 100 shown here

  1. Zheng Z, Travagli R. Dopamine effects on identified rat vagal motoneurons. Am J Physiol Gastrointest Liver Physiol. 2007;292:G1002-8 pubmed
    ..Our data suggest that DA modulates the membrane properties of gastric-projecting motoneurons via D1- and D2-like receptors, and DA may play different roles than norepinephrine in brain stem vagal circuits. ..
  2. Primeaux S, Barnes M, Bray G. Olfactory bulbectomy increases food intake and hypothalamic neuropeptide Y in obesity-prone but not obesity-resistant rats. Behav Brain Res. 2007;180:190-6 pubmed
    ..Therefore, strain specific alterations in hypothalamic NPY may account for increased food intake in the obesity-prone rats following OBX, and suggests a potential mechanism to explain the comorbidity of obesity and depression. ..
  3. Elks C, Mariappan N, Haque M, Guggilam A, Majid D, Francis J. Chronic NF-{kappa}B blockade reduces cytosolic and mitochondrial oxidative stress and attenuates renal injury and hypertension in SHR. Am J Physiol Renal Physiol. 2009;296:F298-305 pubmed publisher
    ..These findings suggest that NF-kappaB activation by ROS induces the cytosolic and mitochondrial oxidative stress and tissue injury that contribute to renal dysfunction observed in SHR...
  4. Browning K, Travagli R. Modulation of inhibitory neurotransmission in brainstem vagal circuits by NPY and PYY is controlled by cAMP levels. Neurogastroenterol Motil. 2009;21:1309-e126 pubmed publisher
    ..These results suggest that, similar to opioid peptides, the effects of pancreatic polypeptides on GABAergic transmission depend upon the levels of cAMP within gastric inhibitory vagal circuits. ..
  5. Tong M, Qualls Creekmore E, Browning K, Travagli R, Holmes G. Experimental spinal cord injury in rats diminishes vagally-mediated gastric responses to cholecystokinin-8s. Neurogastroenterol Motil. 2011;23:e69-79 pubmed publisher
    ..Our data indicate alterations of vagal responses to CCK-8s in T3-SCI rats that may reflect a generalized impairment of gastric vagal neurocircuitry, leading to a reduction of gastric functions after SCI. ..
  6. Burke S, Karlstad M, Eder A, Regal K, Lu D, Burk D, et al. Pancreatic ?-Cell production of CXCR3 ligands precedes diabetes onset. Biofactors. 2016;42:703-715 pubmed publisher
    ..2016 BioFactors, 42(6):703-715, 2016. ..
  7. Harris R, Mitchell T, Simpson J, Redmann S, Youngblood B, Ryan D. Weight loss in rats exposed to repeated acute restraint stress is independent of energy or leptin status. Am J Physiol Regul Integr Comp Physiol. 2002;282:R77-88 pubmed
    ..These results indicate that repeated acute stress induces a chronic change in weight independent of stress-induced hypophagia and may represent a change in homeostasis initiated by repeated acute activation of the central CRF system...
  8. Zhou J, Hegsted M, McCutcheon K, Keenan M, Xi X, Raggio A, et al. Peptide YY and proglucagon mRNA expression patterns and regulation in the gut. Obesity (Silver Spring). 2006;14:683-9 pubmed
    ..Our data provide evidence that the distal part of the gut has the ability to sense nutrients such as butyrate, resulting in the up-regulation of PYY and proglucagon gene expression. ..
  9. Cao F, Donnarumma F, Murray K. Particle size measurement from infrared laser ablation of tissue. Analyst. 2016;141:183-90 pubmed publisher
    ..The implications of these results for laser ablation sampling and mass spectrometry imaging under ambient conditions are discussed. ..
  10. Mastronardi C, Yu W, McCann S. Lipopolysaccharide-induced tumor necrosis factor-alpha release is controlled by the central nervous system. Neuroimmunomodulation. 2001;9:148-56 pubmed
    ..The suppressive action of bromoergocryptine, a dopamine D2 receptor agonist, on LPS-induced TNF-alpha release may be mediated in part by suppression of prolactin release, which triggers TNF-alpha release. ..
  11. Lin L, York D. Amygdala enterostatin induces c-Fos expression in regions of hypothalamus that innervate the PVN. Brain Res. 2004;1020:147-53 pubmed
  12. Yao S, Prpic V, Pan F, Wise G. TNF-alpha upregulates expression of BMP-2 and BMP-3 genes in the rat dental follicle--implications for tooth eruption. Connect Tissue Res. 2010;51:59-66 pubmed publisher
    ..Immunostaining and ELISA showed that BMP-2 and BMP-3 were synthesized and secreted. This study suggests that TNF-alpha can upregulate the expression of bone formation genes that may be needed for tooth eruption. ..
  13. Pryor W, Stone K, Zang L, Bermudez E. Fractionation of aqueous cigarette tar extracts: fractions that contain the tar radical cause DNA damage. Chem Res Toxicol. 1998;11:441-8 pubmed
    ..The tar radical associates with DNA, causes DNA damage, and very likely is involved in the toxicity associated with cigarette smoking. ..
  14. Berthoud H, Patterson L, Zheng H. Vagal-enteric interface: vagal activation-induced expression of c-Fos and p-CREB in neurons of the upper gastrointestinal tract and pancreas. Anat Rec. 2001;262:29-40 pubmed
    ..They represent the first step in the identification of function-specific units of parasympathetic vagal outflow. ..
  15. Berthoud H, Lynn P, Blackshaw L. Vagal and spinal mechanosensors in the rat stomach and colon have multiple receptive fields. Am J Physiol Regul Integr Comp Physiol. 2001;280:R1371-81 pubmed
    ..We conclude that a proportion of gastrointestinal mechanosensors has multiple receptive fields and suggest that they integrate mechanical and chemical information from an entire organ, constituting the generalists in visceral sensation...
  16. Gilbertson T, Boughter J, Zhang H, Smith D. Distribution of gustatory sensitivities in rat taste cells: whole-cell responses to apical chemical stimulation. J Neurosci. 2001;21:4931-41 pubmed
    ..4%) to three, and 8 (13.6%) to all of the basic stimuli. Cells with both inward (Na(+)) and outward (K(+)) voltage-activated currents were significantly more broadly tuned to gustatory stimuli than those with only inward currents. ..
  17. Li B, Xi X, Roane D, Ryan D, Martin R. Distribution of glucokinase, glucose transporter GLUT2, sulfonylurea receptor-1, glucagon-like peptide-1 receptor and neuropeptide Y messenger RNAs in rat brain by quantitative real time RT-PCR. Brain Res Mol Brain Res. 2003;113:139-42 pubmed
    ..In this study, we combined tissue micropunch and real time reverse transcription polymerase chain reaction (RT-PCR), and measured GK, GLUT2, SUR1, GLP-1R and NPY mRNA expression in discrete areas in the hypothalamus and the hindbrain. ..
  18. Zheng H, Patterson L, Morrison C, Banfield B, Randall J, Browning K, et al. Melanin concentrating hormone innervation of caudal brainstem areas involved in gastrointestinal functions and energy balance. Neuroscience. 2005;135:611-25 pubmed
    ..Projections to ventral medullary sites may play a role in the inhibitory effect of melanin-concentrating hormone on energy expenditure. ..
  19. Yao S, Pan F, Wise G. Chronological gene expression of parathyroid hormone-related protein (PTHrP) in the stellate reticulum of the rat: implications for tooth eruption. Arch Oral Biol. 2007;52:228-32 pubmed
  20. Tong M, Holmes G. Gastric dysreflexia after acute experimental spinal cord injury in rats. Neurogastroenterol Motil. 2009;21:197-206 pubmed publisher
    ..Our data suggest that SCI may alter the sensitivity of vagal reflex function, perhaps by interrupting ascending spinosolitary input to brainstem vagal nuclei. ..
  21. Gao Z, Zhang J, Kheterpal I, Kennedy N, Davis R, Ye J. Sirtuin 1 (SIRT1) protein degradation in response to persistent c-Jun N-terminal kinase 1 (JNK1) activation contributes to hepatic steatosis in obesity. J Biol Chem. 2011;286:22227-34 pubmed publisher
    ..JNK2 exhibits an opposite activity in the regulation of SIRT1 degradation. The JNK1-SIRT1 pathway provides a new molecular mechanism for the pathogenesis of hepatic steatosis in obesity. ..
  22. Shen L, Keenan M, Raggio A, Williams C, Martin R. Dietary-resistant starch improves maternal glycemic control in Goto-Kakizaki rat. Mol Nutr Food Res. 2011;55:1499-508 pubmed publisher
    ..Dietary RS is potentially of great therapeutic importance in the treatment of diabetes and improvement in outcomes of pregnancy complicated by diabetes. ..
  23. Advokat C. Update on amphetamine neurotoxicity and its relevance to the treatment of ADHD. J Atten Disord. 2007;11:8-16 pubmed
    ..Clarification of the neurological consequences of chronic AMPH treatment for ADHD is needed. ..
  24. Zheng H, Patterson L, Phifer C, Berthoud H. Brain stem melanocortinergic modulation of meal size and identification of hypothalamic POMC projections. Am J Physiol Regul Integr Comp Physiol. 2005;289:R247-58 pubmed
  25. Qualls Creekmore E, Tong M, Holmes G. Gastric emptying of enterally administered liquid meal in conscious rats and during sustained anaesthesia. Neurogastroenterol Motil. 2010;22:181-5 pubmed publisher
    ..We suggest that Inactin(R), not urethane, is the more suitable anaesthetic for gastrointestinal research. ..
  26. Cardinale J, Sriramula S, Pariaut R, Guggilam A, Mariappan N, Elks C, et al. HDAC inhibition attenuates inflammatory, hypertrophic, and hypertensive responses in spontaneously hypertensive rats. Hypertension. 2010;56:437-44 pubmed publisher
  27. Wise G, He H, Gutierrez D, Ring S, Yao S. Requirement of alveolar bone formation for eruption of rat molars. Eur J Oral Sci. 2011;119:333-8 pubmed publisher
    ..These studies show that alveolar bone growth at the base of the crypt is required for tooth eruption and that Bmp6 may be essential for promoting this growth. ..
  28. Sriramula S, Cardinale J, Lazartigues E, Francis J. ACE2 overexpression in the paraventricular nucleus attenuates angiotensin II-induced hypertension. Cardiovasc Res. 2011;92:401-8 pubmed publisher
  29. Obanda D, Cefalu W. Modulation of cellular insulin signaling and PTP1B effects by lipid metabolites in skeletal muscle cells. J Nutr Biochem. 2013;24:1529-37 pubmed publisher
    ..A clear relationship between PTP1B phosphorylation levels at Ser 50 and its negative effect on insulin signaling is shown. ..
  30. Hermann G, Rogers R. TNF activates astrocytes and catecholaminergic neurons in the solitary nucleus: implications for autonomic control. Brain Res. 2009;1273:72-82 pubmed publisher
  31. Lupachyk S, Watcho P, Hasanova N, Julius U, Obrosova I. Triglyceride, nonesterified fatty acids, and prediabetic neuropathy: role for oxidative-nitrosative stress. Free Radic Biol Med. 2012;52:1255-63 pubmed publisher
    ..In conclusion, hypertriglyceridemia and/or increased NEFA concentrations cause prediabetic neuropathy through oxidative-nitrosative stress. Lipid-lowering agents and antioxidants may find a use in the management of this condition. ..
  32. Zvonic S, Lefevre M, Kilroy G, Floyd Z, Delany J, Kheterpal I, et al. Secretome of primary cultures of human adipose-derived stem cells: modulation of serpins by adipogenesis. Mol Cell Proteomics. 2007;6:18-28 pubmed
    ..These findings, together with the recent identification of vaspin, suggest that the serpin protein family warrants further proteomics investigation with respect to the etiology of obesity and type 2 diabetes. ..
  33. Crousillac S, Colonna J, McMains E, Dewey J, Gleason E. Sphingosine-1-phosphate elicits receptor-dependent calcium signaling in retinal amacrine cells. J Neurophysiol. 2009;102:3295-309 pubmed publisher
    ..Elucidation of the downstream effects of these signals will provide clues to the role of S1P in regulating inner retinal function. ..
  34. Harper J, Sussman M, Schaller G, Putnam Evans C, Charbonneau H, Harmon A. A calcium-dependent protein kinase with a regulatory domain similar to calmodulin. Science. 1991;252:951-4 pubmed
    ..The predicted structure of this kinase explains its direct regulation via calcium binding and establishes it as a prototype for a new family of calcium-regulated protein kinases...
  35. Singer L, York D, Bray G. Macronutrient selection following 2-deoxy-D-glucose and mercaptoacetate administration in rats. Physiol Behav. 1998;65:115-21 pubmed
    ..2-DG increases the intake of carbohydrate which may be necessary to overcome the central glucoprivation caused by this drug. ..
  36. Zvonic S, Hogan J, Arbour Reily P, Mynatt R, Stephens J. Effects of cardiotrophin on adipocytes. J Biol Chem. 2004;279:47572-9 pubmed
    ..In summary, CT-1 is a potent regulator of signaling in adipocytes in vitro and in vivo, and our current efforts are focused on determining the role of this cardioprotective cytokine on adipocyte physiology. ..
  37. Rogers R, Travagli R, Hermann G. Noradrenergic neurons in the rat solitary nucleus participate in the esophageal-gastric relaxation reflex. Am J Physiol Regul Integr Comp Physiol. 2003;285:R479-89 pubmed
  38. Pasarica M, Shin A, Yu M, Ou Yang H, Rathod M, Jen K, et al. Human adenovirus 36 induces adiposity, increases insulin sensitivity, and alters hypothalamic monoamines in rats. Obesity (Silver Spring). 2006;14:1905-13 pubmed
    ..Involvement of the central nervous system (CNS) or adipose tissue in the mechanism of Ad-36-induced adiposity is unknown. The effects of Ad-36 on adiposity and on the neuroendocrine system were investigated in a rat model...
  39. Pasarica M, Loiler S, Dhurandhar N. Acute effect of infection by adipogenic human adenovirus Ad36. Arch Virol. 2008;153:2097-102 pubmed publisher
    ..The serum cytokine response was markedly down-regulated. Ad36 acutely suppresses the systemic immune response and spreads widely. This information will help to determine Ad36 tissue tropism and its metabolic consequences. ..
  40. Dasuri K, Ebenezer P, Zhang L, Fernandez Kim S, Bruce Keller A, Markesbery W, et al. Increased protein hydrophobicity in response to aging and Alzheimer disease. Free Radic Biol Med. 2010;48:1330-7 pubmed publisher
    ..Our studies also suggest a potential role for decreased oxidized and hydrophobic proteins in mediating the beneficial effects of DR. ..
  41. Obrosova I, Maksimchyk Y, Pacher P, Agardh E, Smith M, El Remessy A, et al. Evaluation of the aldose reductase inhibitor fidarestat on ischemia-reperfusion injury in rat retina. Int J Mol Med. 2010;26:135-42 pubmed
    ..The results identify AR as an important therapeutic target for diseases involving IR injury, and provide the rationale for development of fidarestat and other AR inhibitors. ..
  42. Agarwal D, Elks C, Reed S, Mariappan N, Majid D, Francis J. Chronic exercise preserves renal structure and hemodynamics in spontaneously hypertensive rats. Antioxid Redox Signal. 2012;16:139-52 pubmed publisher
    ..Chronic ExT preserves renal hemodynamics and structure in SHR; these effects are partially mediated by improved redox status and decreased inflammation. ..
  43. McDougal D, Hermann G, Rogers R. Vagal afferent stimulation activates astrocytes in the nucleus of the solitary tract via AMPA receptors: evidence of an atypical neural-glial interaction in the brainstem. J Neurosci. 2011;31:14037-45 pubmed publisher
    ..These observations suggest that NST astrocytes may be active participants in the regulation of autonomic reflexes even in the normal, healthy state. ..
  44. Lupachyk S, Stavniichuk R, Komissarenko J, Drel V, Obrosov A, El Remessy A, et al. Na+/H+-exchanger-1 inhibition counteracts diabetic cataract formation and retinal oxidative-nitrative stress and apoptosis. Int J Mol Med. 2012;29:989-98 pubmed publisher
    ..In conclusion, NHE-1 contributes to diabetic cataract formation, and retinal oxidative-nitrative stress and apoptosis. The findings identify a new therapeutic target for diabetic ocular complications. ..
  45. Rogers P, Fusinski K, Rathod M, Loiler S, Pasarica M, Shaw M, et al. Human adenovirus Ad-36 induces adipogenesis via its E4 orf-1 gene. Int J Obes (Lond). 2008;32:397-406 pubmed
    ..Therefore, we investigated the role of Ad-36 as a novel regulator of the adipogenic process...
  46. Drel V, Pacher P, Ali T, Shin J, Julius U, El Remessy A, et al. Aldose reductase inhibitor fidarestat counteracts diabetes-associated cataract formation, retinal oxidative-nitrosative stress, glial activation, and apoptosis. Int J Mol Med. 2008;21:667-76 pubmed
  47. Shevalye H, Watcho P, Stavniichuk R, Dyukova E, Lupachyk S, Obrosova I. Metanx alleviates multiple manifestations of peripheral neuropathy and increases intraepidermal nerve fiber density in Zucker diabetic fatty rats. Diabetes. 2012;61:2126-33 pubmed publisher
    ..Clinical studies are needed to determine if Metanx finds use in management of diabetic peripheral neuropathy. ..
  48. Holmes G. 5-Hydroxytryptamine2C receptors on pudendal motoneurons innervating the external anal sphincter. Brain Res. 2005;1057:65-71 pubmed
    ..These data suggest that previously identified descending serotonergic immunopositive fibers observed terminating on EAS motoneurons might mediate their input through the activation of 5-HT2C receptors. ..
  49. Browning K, Zheng Z, Gettys T, Travagli R. Vagal afferent control of opioidergic effects in rat brainstem circuits. J Physiol. 2006;575:761-76 pubmed
    ..These data suggest that the plasticity, hence the response, of central circuits controlling the vagal motor outflow to visceral organs is modulated and finely tuned by vagal afferent fibres. ..
  50. Gupta S, Knight A, Gupta S, Keller J, Bruce Keller A. Saturated long-chain fatty acids activate inflammatory signaling in astrocytes. J Neurochem. 2012;120:1060-71 pubmed publisher
  51. Tu H, Kastin A, Bjorbaek C, Pan W. Urocortin trafficking in cerebral microvessel endothelial cells. J Mol Neurosci. 2007;31:171-81 pubmed
    ..Thus, urocortin endocytosis is a saturable process leading to vesicular intracellular transport that can be enhanced by cell-surface leptin. ..
  52. Zhang Y, Huypens P, Adamson A, Chang J, Henagan T, Boudreau A, et al. Alternative mRNA splicing produces a novel biologically active short isoform of PGC-1alpha. J Biol Chem. 2009;284:32813-26 pubmed publisher
    ..Therefore, NT-PGC-1alpha is a co-expressed, previously unrecognized form of PGC-1alpha with functions that are both unique from and complementary to PGC-1alpha. ..
  53. Pan W, Tu H, Kastin A. Differential BBB interactions of three ingestive peptides: obestatin, ghrelin, and adiponectin. Peptides. 2006;27:911-6 pubmed
    ..The differential interactions of obestatin, adiponectin, and ghrelin with the BBB illustrate their distinctive physiological interactions with the CNS. ..
  54. Pan W, Kastin A. From MIF-1 to endomorphin: the Tyr-MIF-1 family of peptides. Peptides. 2007;28:2411-34 pubmed
    ..These peptides clearly illustrate that the name of a peptide restricts neither its actions nor its conceptual implications. ..
  55. Yu C, Argyropoulos G, Zhang Y, Kastin A, Hsuchou H, Pan W. Neuroinflammation activates Mdr1b efflux transport through NFkappaB: promoter analysis in BBB endothelia. Cell Physiol Biochem. 2008;22:745-56 pubmed publisher
    ..NFkappaB mediates TNF-induced upregulation of mdr1b promoter activity, illustrating how inflammation activates BBB efflux transport. ..
  56. Vandergrifft E, Swiderski C, Horohov D. Molecular cloning and sequencing of equine interleukin 4. Vet Immunol Immunopathol. 1994;40:379-84 pubmed
    ..The cDNA was amplified from mitogen-stimulated equine peripheral blood mononuclear cells (PBMC). The cloned PCR product shares extensive homology ith IL-4 sequences from other species...
  57. Truett G, Walker J, Brock J. A rat homolog of the mouse deafness mutant jerker (je). Mamm Genome. 1996;7:356-8 pubmed
    ..It seems likely that the mutation affects the rat homolog of je. The rat deafness locus should, therefore, be named jerker and assigned the gene symbol Je. ..
  58. Ramsay T, Yan X, Morrison C. The obesity gene in swine: sequence and expression of porcine leptin. J Anim Sci. 1998;76:484-90 pubmed
    ..These data indicate that leptin is expressed in pigs, the expressed protein is secreted into the bloodstream, and obese swine express higher levels of leptin mRNA and protein than nonobese swine at similar body weight. ..
  59. Rogers R, Van Meter M, Hermann G. Tumor necrosis factor potentiates central vagal afferent signaling by modulating ryanodine channels. J Neurosci. 2006;26:12642-6 pubmed
    ..Such a scheme may explain how TNF sensitizes visceral as well as somatosensory primary afferents. ..
  60. Wan S, Coleman F, Travagli R. Cholecystokinin-8s excites identified rat pancreatic-projecting vagal motoneurons. Am J Physiol Gastrointest Liver Physiol. 2007;293:G484-92 pubmed
    ..These data indicate that CCK-8s may control pancreas-exocrine secretion also via an effect on pancreas-projecting DMV neurons. ..
  61. Rogers R, Viard E, Hermann G. CXCL12 sensitizes vago-vagal reflex neurons in the dorsal medulla. Brain Res. 2013;1492:46-52 pubmed publisher
  62. Yang W, Mason C, Pollock S, Lavezzi T, Moroney J, Moore T. Membrane lipid biosynthesis in Chlamydomonas reinhardtii: expression and characterization of CTP:phosphoethanolamine cytidylyltransferase. Biochem J. 2004;382:51-7 pubmed
    ..reinhardtii cells was observed during the cell cycle, increasing during the dark and then decreasing during the light period, while the mRNA level did not alter, providing evidence for post-translational regulation. ..
  63. White C, Whittington A, Barnes M, Wang Z, Bray G, Morrison C. HF diets increase hypothalamic PTP1B and induce leptin resistance through both leptin-dependent and -independent mechanisms. Am J Physiol Endocrinol Metab. 2009;296:E291-9 pubmed publisher
    ..Therefore, additional, leptin-independent mechanisms must exist that increase hypothalamic PTP1B and contribute to leptin resistance. ..
  64. Agarwal D, Welsch M, Keller J, Francis J. Chronic exercise modulates RAS components and improves balance between pro- and anti-inflammatory cytokines in the brain of SHR. Basic Res Cardiol. 2011;106:1069-85 pubmed publisher
  65. Mumphrey M, Patterson L, Zheng H, Berthoud H. Roux-en-Y gastric bypass surgery increases number but not density of CCK-, GLP-1-, 5-HT-, and neurotensin-expressing enteroendocrine cells in rats. Neurogastroenterol Motil. 2013;25:e70-9 pubmed publisher
    ..Whether changes in releasing stimuli also contribute to altered circulating levels will have to be determined in future studies. ..
  66. Wan S, Coleman F, Travagli R. Glucagon-like peptide-1 excites pancreas-projecting preganglionic vagal motoneurons. Am J Physiol Gastrointest Liver Physiol. 2007;292:G1474-82 pubmed
    ..e., putative endocrine secretion-controlling neurons) could be distinguished from neurons responsive to PP (i.e., putative exocrine secretion-controlling neurons). ..
  67. Morrison C, White C, Wang Z, Lee S, Lawrence D, Cefalu W, et al. Increased hypothalamic protein tyrosine phosphatase 1B contributes to leptin resistance with age. Endocrinology. 2007;148:433-40 pubmed
    ..05). These data are consistent with the hypothesis that increases in PTP1B contribute to hypothalamic leptin resistance as rats transition into middle age. ..
  68. Zheng H, Patterson L, Berthoud H. Orexin signaling in the ventral tegmental area is required for high-fat appetite induced by opioid stimulation of the nucleus accumbens. J Neurosci. 2007;27:11075-82 pubmed
  69. Zhang Y, Kerman I, Laque A, Nguyen P, Faouzi M, Louis G, et al. Leptin-receptor-expressing neurons in the dorsomedial hypothalamus and median preoptic area regulate sympathetic brown adipose tissue circuits. J Neurosci. 2011;31:1873-84 pubmed publisher
    ..2008). Thus, these data present strong evidence that LepRb neurons in the DMH/DHA and mPOA mediate thermoregulatory leptin action. ..
  70. Lupachyk S, Watcho P, Shevalye H, Vareniuk I, Obrosov A, Obrosova I, et al. Na+/H+ exchanger 1 inhibition reverses manifestation of peripheral diabetic neuropathy in type 1 diabetic rats. Am J Physiol Endocrinol Metab. 2013;305:E396-404 pubmed publisher
  71. Berthoud H, Kressel M, Neuhuber W. Vagal afferent innervation of rat abdominal paraganglia as revealed by anterograde DiI-tracing and confocal microscopy. Acta Anat (Basel). 1995;152:127-32 pubmed
    ..These findings support the concept of a chemoreceptive function for the abdominal paraganglia. ..
  72. David A, Saied A, Charles A, Subramanian R, Chouljenko V, Kousoulas K. A herpes simplex virus 1 (McKrae) mutant lacking the glycoprotein K gene is unable to infect via neuronal axons and egress from neuronal cell bodies. MBio. 2012;3:e00144-12 pubmed publisher
    ..In addition, lack of gK expression prevented anterograde transmission of virions. These results suggest that gK is a critical determinant for neuronal infection and transmission...
  73. Suchankova G, Tekle M, Saha A, Ruderman N, Clarke S, Gettys T. Dietary polyunsaturated fatty acids enhance hepatic AMP-activated protein kinase activity in rats. Biochem Biophys Res Commun. 2005;326:851-8 pubmed
  74. Shevalye H, Stavniichuk R, Xu W, Zhang J, Lupachyk S, Maksimchyk Y, et al. Poly(ADP-ribose) polymerase (PARP) inhibition counteracts multiple manifestations of kidney disease in long-term streptozotocin-diabetic rat model. Biochem Pharmacol. 2010;79:1007-14 pubmed publisher
    ..These findings provide rationale for development and further studies of PARP inhibitors and PARP inhibitor-containing combination therapies, for prevention and treatment of diabetic nephropathy. ..
  75. Ngoc Tran T, Stovall K, Suantawee T, Hu Y, Yao S, Yang L, et al. Transient receptor potential melastatin 4 channel is required for rat dental pulp stem cell proliferation and survival. Cell Prolif. 2017;50: pubmed publisher
    ..These data suggest that the shape and frequency of intracellular Ca2+ signals may mediate stem cell proliferation and survival. ..
  76. Baker D. Natural pathogens of laboratory mice, rats, and rabbits and their effects on research. Clin Microbiol Rev. 1998;11:231-66 pubmed
    ..Investigators using mice, rats, and rabbits in biomedical experimentation should be aware of the profound effects that many of these agents can have on research. ..
  77. Zheng H, Corkern M, Stoyanova I, Patterson L, Tian R, Berthoud H. Peptides that regulate food intake: appetite-inducing accumbens manipulation activates hypothalamic orexin neurons and inhibits POMC neurons. Am J Physiol Regul Integr Comp Physiol. 2003;284:R1436-44 pubmed
    ..However, activation of many neurons not expressing these peptides suggests that additional peptides/transmitters in the lateral hypothalamus and accumbens projections to other brain areas might also be involved. ..
  78. Wise G, Yao S. Expression of vascular endothelial growth factor in the dental follicle. Crit Rev Eukaryot Gene Expr. 2003;13:173-80 pubmed
    ..Treatment with PMA also increased the protein level of VEGF. Thus, VEGF may be involved in promoting the secondary burst of osteoclastogenesis, and activation of PKC may upregulate its expression. ..
  79. Sutton G, Patterson L, Berthoud H. Extracellular signal-regulated kinase 1/2 signaling pathway in solitary nucleus mediates cholecystokinin-induced suppression of food intake in rats. J Neurosci. 2004;24:10240-7 pubmed
  80. Wan S, Browning K. Glucose increases synaptic transmission from vagal afferent central nerve terminals via modulation of 5-HT3 receptors. Am J Physiol Gastrointest Liver Physiol. 2008;295:G1050-7 pubmed publisher
  81. Yao S, Gutierrez D, Ring S, Liu D, Wise G. Electroporation to deliver plasmid DNA into rat dental tissues. J Gene Med. 2010;12:981-9 pubmed publisher
    ..This protocol could be used to deliver short hairpin RNA or genes of interest into the dental tissues to regulate tooth eruption. Thus, it may be possible to develop nonsurgical treatments for inducing the eruption of impacted teeth. ..
  82. Lupachyk S, Shevalye H, Maksimchyk Y, Drel V, Obrosova I. PARP inhibition alleviates diabetes-induced systemic oxidative stress and neural tissue 4-hydroxynonenal adduct accumulation: correlation with peripheral nerve function. Free Radic Biol Med. 2011;50:1400-9 pubmed publisher
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