Experts and Doctors on helix loop helix motifs in Indianapolis, Indiana, United States

Summary

Locale: Indianapolis, Indiana, United States
Topic: helix loop helix motifs

Top Publications

  1. Firulli A. A HANDful of questions: the molecular biology of the heart and neural crest derivatives (HAND)-subclass of basic helix-loop-helix transcription factors. Gene. 2003;312:27-40 pubmed
  2. Firulli B, Howard M, McDaid J, McIlreavey L, Dionne K, Centonze V, et al. PKA, PKC, and the protein phosphatase 2A influence HAND factor function: a mechanism for tissue-specific transcriptional regulation. Mol Cell. 2003;12:1225-37 pubmed
    ..Mutations in phosphorylated residues result in altered HAND1 dimerization and biological function. Taken together, these results suggest that site-specific phosphorylation regulates HAND factor functional specificity. ..
  3. Firulli B, Krawchuk D, Centonze V, Vargesson N, Virshup D, Conway S, et al. Altered Twist1 and Hand2 dimerization is associated with Saethre-Chotzen syndrome and limb abnormalities. Nat Genet. 2005;37:373-81 pubmed publisher

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