Experts and Doctors on animals in Evanston, Illinois, United States

Summary

Locale: Evanston, Illinois, United States
Topic: animals

Top Publications

  1. Weraarchakul Boonmark N, Jeong J, Murthy S, Engel J, Lorand L. Cloning and expression of chicken erythrocyte transglutaminase. Proc Natl Acad Sci U S A. 1992;89:9804-8 pubmed
    ..Chicken erythrocyte transglutaminase mRNA is most abundant in red blood cells and kidney, and it accumulates during erythroid cell differentiation. ..
  2. Vitaterna M, Wu J, Turek F, Pinto L. Reduced light sensitivity of the circadian clock in a hypopigmented mouse mutant. Exp Brain Res. 1993;95:436-42 pubmed
    ..Taken together, these results indicate that while basic characteristics of circadian clock function are not altered by the pink-eyed dilution mutation, the sensitivity of the clock to light is reduced.(ABSTRACT TRUNCATED AT 250 WORDS) ..
  3. Lin J, Kilman V, Keegan K, Paddock B, Emery Le M, Rosbash M, et al. A role for casein kinase 2alpha in the Drosophila circadian clock. Nature. 2002;420:816-20 pubmed
    ..These effects are probably direct, as CK2alpha specifically phosphorylates Per in vitro. We propose that CK2 is an evolutionary link between the divergent circadian systems of animals, plants and fungi. ..
  4. Schlitt B, Felrice M, Jelachich M, Lipton H. Apoptotic cells, including macrophages, are prominent in Theiler's virus-induced inflammatory, demyelinating lesions. J Virol. 2003;77:4383-8 pubmed
    ..T cells comprised 74% of apoptotic cells, while 8% were macrophages, 0.6% were astrocytes, and approximately 17% remained unidentified. In situ hybridization revealed viral RNA in approximately 1% of apoptotic cells. ..
  5. Liu S, Tieche C, Tang D, Alkema P. Pattern formation of vascular smooth muscle cells subject to nonuniform fluid shear stress: role of PDGF-beta receptor and Src. Am J Physiol Heart Circ Physiol. 2003;285:H1081-90 pubmed
    ..These observations suggest that PDGF-beta receptor and Src possibly serve as mediating factors in nonuniform shear-induced formation of cell density gradients and alignment of SMCs in the neointima of vascular polymer implants. ..
  6. Rudick C, Gibbs R, Woolley C. A role for the basal forebrain cholinergic system in estrogen-induced disinhibition of hippocampal pyramidal cells. J Neurosci. 2003;23:4479-90 pubmed
  7. Burdette J, Kurley S, Kilen S, Mayo K, Woodruff T. Gonadotropin-induced superovulation drives ovarian surface epithelia proliferation in CD1 mice. Endocrinology. 2006;147:2338-45 pubmed
    ..Therefore, ovarian surface cell division in response to ovulation could contribute to ovarian cancer by proliferation-induced DNA mutations and transformed cell progression. ..
  8. Lim C, Chung B, Pitman J, McGill J, Pradhan S, Lee J, et al. Clockwork orange encodes a transcriptional repressor important for circadian-clock amplitude in Drosophila. Curr Biol. 2007;17:1082-9 pubmed
    ..Molecular analysis suggests that CWO acts, in part, by repressing CLK target genes. We propose that CWO acts as a transcriptional and behavioral rhythm amplifier. ..
  9. Prahlad V, Cornelius T, Morimoto R. Regulation of the cellular heat shock response in Caenorhabditis elegans by thermosensory neurons. Science. 2008;320:811-4 pubmed publisher
    ..We propose a model whereby this loss of cell autonomy serves to integrate behavioral, metabolic, and stress-related responses to establish an organismal response to environmental change. ..

More Information

Publications483 found, 100 shown here

  1. Dallos P. Cochlear amplification, outer hair cells and prestin. Curr Opin Neurobiol. 2008;18:370-6 pubmed publisher
    ..One of the central outstanding problems in mammalian cochlear neurobiology is the relation between the two amplification processes. ..
  2. Feng H, Chen M, Weinstein L, Jin J. Removal of the N-terminal extension of cardiac troponin I as a functional compensation for impaired myocardial beta-adrenergic signaling. J Biol Chem. 2008;283:33384-93 pubmed publisher
    ..These data indicate that the up-regulation of cTnI-ND may partially compensate for the cardiac inefficiency in impaired beta-adrenergic signaling. ..
  3. Voisine C, Pedersen J, Morimoto R. Chaperone networks: tipping the balance in protein folding diseases. Neurobiol Dis. 2010;40:12-20 pubmed publisher
    ..These events appear to be further amplified by aging and provide evidence that age-related failures in proteostasis may be a common element in many diseases. ..
  4. Kumar G, Xie T, Zhang Y, Radhakrishnan I. Solution structure of the mSin3A PAH2-Pf1 SID1 complex: a Mad1/Mxd1-like interaction disrupted by MRG15 in the Rpd3S/Sin3S complex. J Mol Biol. 2011;408:987-1000 pubmed publisher
  5. Prasad M, Sauka Spengler T, LaBonne C. Induction of the neural crest state: control of stem cell attributes by gene regulatory, post-transcriptional and epigenetic interactions. Dev Biol. 2012;366:10-21 pubmed publisher
  6. Buggele W, Johnson K, Horvath C. Influenza A virus infection of human respiratory cells induces primary microRNA expression. J Biol Chem. 2012;287:31027-40 pubmed publisher
    ..Gene expression profiling identified 26 cellular mRNAs targeted by these miRNAs, including IRAK1, MAPK3, and other components of innate immune signaling systems. ..
  7. Rima B, Collins P, Easton A, Fouchier R, Kurath G, Lamb R, et al. ICTV Virus Taxonomy Profile: Pneumoviridae. J Gen Virol. 2017;: pubmed publisher
    ..This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the taxonomy of the Pneumoviridae, which is available at www.ictv.global/report/pneumoviridae...
  8. Holsinger L, Lamb R. Influenza virus M2 integral membrane protein is a homotetramer stabilized by formation of disulfide bonds. Virology. 1991;183:32-43 pubmed
    ..Taken together, these data suggest that disulfide bond formation, although not essential for oligomeric assembly, stabilizes the M2 tetramer from disruption by detergent solubilization. ..
  9. Challet E, Bernard D, Turek F. Lesions of glucose-responsive neurons impair synchronizing effects of calorie restriction in mice. Brain Res. 1998;801:244-50 pubmed
    ..Therefore, glucose-responsive neurons in the ventromedial hypothalamus may play a role in the synchronizing effects of calorie restriction on circadian rhythmicity. ..
  10. Bejsovec A. Wnt signalling shows its versatility. Curr Biol. 1999;9:R684-7 pubmed
    ..Recent studies have revealed that regulatory interactions at several steps in the pathway can modify its outcome, helping to explain how the same pathway can, in different contexts, have very different characteristics and consequences. ..
  11. Wang Q, Holmgren R. The subcellular localization and activity of Drosophila cubitus interruptus are regulated at multiple levels. Development. 1999;126:5097-106 pubmed
    ..Finally, we propose that there are three levels of apparent Ci activity, corresponding to three zones along the AP axis with different sets of gene expression and different levels of Hh signaling. ..
  12. Fisher K, Telser A, Phillips J, Yeates D. Regulation of vocal fold transepithelial water fluxes. J Appl Physiol (1985). 2001;91:1401-11 pubmed
    ..05). The presence of the Na(+)-K(+)-ATPase in the vocal fold epithelium and the electrolyte transport derived from its activity provide the intrinsic mechanisms to regulate cell volume as well as vocal fold hydration...
  13. Romito L, Ameer G. Mechanical interlocking of engineered cartilage to an underlying polymeric substrate: towards a biohybrid tissue equivalent. Ann Biomed Eng. 2006;34:737-47 pubmed
    ..This study demonstrates the feasibility of creating a biohybrid cartilage equivalent by mechanically interlocking a cartilaginous layer to an underlying polymeric matrix. ..
  14. Koynova R, Wang L, MacDonald R. An intracellular lamellar-nonlamellar phase transition rationalizes the superior performance of some cationic lipid transfection agents. Proc Natl Acad Sci U S A. 2006;103:14373-8 pubmed
    ..These results highlight the phase properties of the carrier lipid/cellular lipid mixtures as a decisive factor for transfection success and suggest a strategy for the rational design of superior cationic lipid carriers. ..
  15. Connolly S, Leser G, Yin H, Jardetzky T, Lamb R. Refolding of a paramyxovirus F protein from prefusion to postfusion conformations observed by liposome binding and electron microscopy. Proc Natl Acad Sci U S A. 2006;103:17903-8 pubmed
    ..The reactivity of the F protein with conformation-specific mAbs and peptide binding suggest that soluble F-GCNt and membrane-bound F proteins refold through a comparable pathway. ..
  16. Izzo A, Walsh J, Jansen E, Bendett M, Webb J, Ralph H, et al. Optical parameter variability in laser nerve stimulation: a study of pulse duration, repetition rate, and wavelength. IEEE Trans Biomed Eng. 2007;54:1108-14 pubmed
    ..The technology of optical stimulation could significantly improve cochlear implants, which are hampered by a lack of spatial selectivity. ..
  17. Rutherford J, Tardif S. Placental efficiency and intrauterine resource allocation strategies in the common marmoset pregnancy. Am J Phys Anthropol. 2008;137:60-8 pubmed publisher
    ..Placental adaptations that solicit potential increases of maternal investment may occur at the microscopic or metabolic level, and thus may not be reflected in the size of the placenta as a whole. ..
  18. Quist B, Hartmann M. A two-dimensional force sensor in the millinewton range for measuring vibrissal contacts. J Neurosci Methods. 2008;172:158-67 pubmed publisher
    ..Given the high fidelity of the sensor, it could have utility in a broad range of applications in which measuring contact/detach occurrence and/or small magnitude forces are important. ..
  19. Zhao W, Lacor P, Chen H, Lambert M, Quon M, Krafft G, et al. Insulin receptor dysfunction impairs cellular clearance of neurotoxic oligomeric a{beta}. J Biol Chem. 2009;284:18742-53 pubmed publisher
    ..Our results suggest that dysfunctions of brain insulin and IGF-1 receptors contribute to Abeta aggregation and subsequent synaptic loss. ..
  20. Hu Z, Robbins J, Pister A, Zafar M, Zhang Z, Gupta J, et al. A modified hTERT promoter-directed oncolytic adenovirus replication with concurrent inhibition of TGFbeta signaling for breast cancer therapy. Cancer Gene Ther. 2010;17:235-43 pubmed publisher
    ..These results warrant future investigation of mhTERTAd.sTbetaRFc as an antitumor agent in vivo. ..
  21. Parrish E, Siletz A, Xu M, Woodruff T, Shea L. Gene expression in mouse ovarian follicle development in vivo versus an ex vivo alginate culture system. Reproduction. 2011;142:309-18 pubmed publisher
    ..These studies establish the similarities and differences between in vivo and in vitro cultured follicles, guiding the creation of environments that maximize follicle development and oocyte quality. ..
  22. Burgdorf J, Moskal J, Brudzynski S, Panksepp J. Rats selectively bred for low levels of play-induced 50 kHz vocalizations as a model for autism spectrum disorders: a role for NMDA receptors. Behav Brain Res. 2013;251:18-24 pubmed publisher
    ..Since the NMDA receptor has been implicated in the genesis of autistic symptoms, it is possible that GLYX-13 may be of therapeutic value in the treatment of autism. ..
  23. MONDRAGON A. Structural studies of RNase P. Annu Rev Biophys. 2013;42:537-57 pubmed publisher
  24. Wilder E, Linzer D. Participation of multiple factors, including proliferin, in the inhibition of myogenic differentiation. Mol Cell Biol. 1989;9:430-41 pubmed
    ..Although expected to function in vivo as an extracellular hormone, PLF did not appear to be acting through a cell surface receptor to inhibit differentiation in these cultured myoblasts. ..
  25. Lin X. Action potentials and underlying voltage-dependent currents studied in cultured spiral ganglion neurons of the postnatal gerbil. Hear Res. 1997;108:157-79 pubmed
    ..Possible roles of spontaneous APs in the development of the cochlea and the role of voltage-gated currents in the function of SG neurons under normal and pathological conditions are discussed. ..
  26. Lin J, Poole J, Linzer D. Three new members of the mouse prolactin/growth hormone family are homologous to proteins expressed in the rat. Endocrinology. 1997;138:5541-9 pubmed
    ..The identification of PRL-related mRNAs in common between the mouse and rat indicates that the encoded hormones are evolutionarily conserved and, therefore, likely to play important roles in reproductive physiology. ..
  27. Mathew A, Mathur S, Morimoto R. Heat shock response and protein degradation: regulation of HSF2 by the ubiquitin-proteasome pathway. Mol Cell Biol. 1998;18:5091-8 pubmed
  28. Derrick M, Luo N, Bregman J, Jilling T, Ji X, Fisher K, et al. Preterm fetal hypoxia-ischemia causes hypertonia and motor deficits in the neonatal rabbit: a model for human cerebral palsy?. J Neurosci. 2004;24:24-34 pubmed
    ..These findings provide a unique behavioral model to define mechanisms and sequelae of perinatal brain injury from antenatal hypoxia-ischemia. ..
  29. Wu V, Beitel G. A junctional problem of apical proportions: epithelial tube-size control by septate junctions in the Drosophila tracheal system. Curr Opin Cell Biol. 2004;16:493-9 pubmed
    ..Possible tube-size functions of septate junctions include patterning of the apical extracellular matrix and regulation of conserved cell polarity genes such as Scribble and Discs Large. ..
  30. Lupu R, Menendez J. Pharmacological inhibitors of Fatty Acid Synthase (FASN)--catalyzed endogenous fatty acid biogenesis: a new family of anti-cancer agents?. Curr Pharm Biotechnol. 2006;7:483-93 pubmed
    ..5 A resolution X-ray crystallographic map of mammalian FASN, will direct the foundation of a new family of chemotherapeutic agents in cancer history. ..
  31. Jones M, Messersmith P. Facile coupling of synthetic peptides and peptide-polymer conjugates to cartilage via transglutaminase enzyme. Biomaterials. 2007;28:5215-24 pubmed
    ..The results illustrate the use of tTG as a simple, effective and biologically compatible method of coupling synthetic and biological molecules to cartilage and other tissues containing ECM proteins that are substrates of tTG. ..
  32. Dallos P, Wu X, Cheatham M, Gao J, Zheng J, Anderson C, et al. Prestin-based outer hair cell motility is necessary for mammalian cochlear amplification. Neuron. 2008;58:333-9 pubmed publisher
    ..These animals have knockout-like behavior, demonstrating that prestin-based electromotility is required for cochlear amplification. ..
  33. Harney A, Lee J, Manus L, Wang P, Ballweg D, LaBonne C, et al. Targeted inhibition of Snail family zinc finger transcription factors by oligonucleotide-Co(III) Schiff base conjugate. Proc Natl Acad Sci U S A. 2009;106:13667-72 pubmed publisher
    ..A complex targeted to inactivate their transcriptional activity could prove valuable as an experimental tool and a cancer therapeutic. ..
  34. Kang M, So E, Ouchi T. Deregulation of DNA damage response pathway by intercellular contact. J Biol Chem. 2012;287:16246-55 pubmed publisher
    ..Together, our results illustrate a novel mechanism of the regulation of DDR proteins by the cadherin-catenin pathway. ..
  35. Lander R, Nasr T, Ochoa S, Nordin K, Prasad M, LaBonne C. Interactions between Twist and other core epithelial-mesenchymal transition factors are controlled by GSK3-mediated phosphorylation. Nat Commun. 2013;4:1542 pubmed publisher
    ..Together, these findings elucidate a mechanism for coordinated control of a group of structurally diverse factors that function as a regulatory unit in both developmental and pathological epithelial-mesenchymal transitions...
  36. Benton M, Lewis A, Bant J, Raman I. Iberiotoxin-sensitive and -insensitive BK currents in Purkinje neuron somata. J Neurophysiol. 2013;109:2528-41 pubmed publisher
    ..Moreover, augmentation of BK current may partially underlie the action of EBIO and chlorzoxazone to alleviate disrupted Purkinje cell firing associated with genetic ataxias. ..
  37. Mirkin C, Stegh A. Spherical nucleic acids for precision medicine. Oncotarget. 2014;5:9-10 pubmed
  38. Cho N, Klein W. Muscarinic acetylcholine receptors from avian retina and heart undergo different patterns of molecular maturation. J Neurochem. 1988;50:1403-11 pubmed
    ..abstract truncated at 250 words)..
  39. Hoeppner M, Gilbert D, Copeland N, Jenkins N, Linzer D, Wu B. Cloning and characterization of mouse CCAAT binding factor. Nucleic Acids Res. 1996;24:1091-8 pubmed
    ..Co-expression of these two forms influences their localization, however, indicating that CBF activity can be regulated by the relative amounts of the two forms expressed in a cell. ..
  40. Whitlon D, Zhang X, Kusakabe M. Tenascin-C in the cochlea of the developing mouse. J Comp Neurol. 1999;406:361-74 pubmed
    ..The presence of tenascin-C along the growth routes of nerve fibers, particularly toward the outer hair cells, raises the possibility that growth cone interactions with tenascin-C helps to guide nerve fibers in the cochlea. ..
  41. Ostrowski S, Dierick H, Bejsovec A. Genetic control of cuticle formation during embryonic development of Drosophila melanogaster. Genetics. 2002;161:171-82 pubmed
  42. Zhang H, Tsang T, Pollack J, Jack C. Evaluation of role of bile flow patterns in process of in vitro stent occlusion. Dig Dis Sci. 2002;47:2691-5 pubmed
    ..In conclusion, flushing of bile may decrease the build-up of substance in vitro and thus improve stent flow rates, for which decreasing bacterial adherence to stents may be responsible...
  43. Menendez J, Mehmi I, Verma V, Teng P, Lupu R. Pharmacological inhibition of fatty acid synthase (FAS): a novel therapeutic approach for breast cancer chemoprevention through its ability to suppress Her-2/neu (erbB-2) oncogene-induced malignant transformation. Mol Carcinog. 2004;41:164-78 pubmed
    ..Our observations strongly suggest that inhibition of FAS activity may provide a new molecular avenue for chemotherapeutic prevention and/or treatment of Her-2/neu-related breast carcinomas. ..
  44. Croker J, Ziegenhorn S, Holmgren R. Regulation of the Drosophila transcription factor, Cubitus interruptus, by two conserved domains. Dev Biol. 2006;291:368-81 pubmed
    ..Analysis of the amino acid sequence of this domain identifies 11 perfectly conserved serines and one tyrosine. We propose that this region may be modified, possibly by phosphorylation, to regulate Ci nuclear import. ..
  45. Zhao Y, Katzman R, Delmolino L, Bhat I, Zhang Y, Gurumurthy C, et al. The notch regulator MAML1 interacts with p53 and functions as a coactivator. J Biol Chem. 2007;282:11969-81 pubmed
    ..elegans p53 homolog Cep-1. Thus, we present evidence for a novel coactivator function of MAML1 for p53, independent of its function as a coactivator of Notch signaling pathway. ..
  46. Bissonnette M, Donald J, Degrado W, Jardetzky T, Lamb R. Functional analysis of the transmembrane domain in paramyxovirus F protein-mediated membrane fusion. J Mol Biol. 2009;386:14-36 pubmed publisher
    ..We suggest that the unusual length of this TM helix might allow it to serve as a template for formation of or specifically stabilize the lipid stalk intermediate in fusion. ..
  47. Miller S, Karpus W, Davidson T. Experimental autoimmune encephalomyelitis in the mouse. Curr Protoc Immunol. 2010;Chapter 15:Unit 15.1 pubmed publisher
    ..A protocol for isolating CNS-infiltrating lymphocytes in EAE mice is included. Modifications of the specified protocols may be necessary for efficient induction of active or adoptive EAE in other mouse strains. ..
  48. Dohm M, Mowery B, Czyzewski A, Stahl S, Gellman S, Barron A. Biophysical mimicry of lung surfactant protein B by random nylon-3 copolymers. J Am Chem Soc. 2010;132:7957-67 pubmed publisher
  49. Ilievski V, Hirsch E. Synergy between viral and bacterial toll-like receptors leads to amplification of inflammatory responses and preterm labor in the mouse. Biol Reprod. 2010;83:767-73 pubmed publisher
  50. Homma K, Dallos P. Evidence that prestin has at least two voltage-dependent steps. J Biol Chem. 2011;286:2297-307 pubmed publisher
    ..Here, we suggest a molecular mechanism of prestin with at least two voltage-dependent conformational transition steps having distinct electromechanical coupling efficiencies. ..
  51. Tiwari A, Crawford S, Radosevich A, Wali R, Stypula Y, Kunte D, et al. Neo-angiogenesis and the premalignant micro-circulatory augmentation of early colon carcinogenesis. Cancer Lett. 2011;306:205-13 pubmed publisher
    ..This finding has potential implications as a biomarker for risk-stratification and target for chemoprevention. ..
  52. Harris D, Kim K, Nakahara K, Vásquez Doorman C, Carthew R. Cargo sorting to lysosome-related organelles regulates siRNA-mediated gene silencing. J Cell Biol. 2011;194:77-87 pubmed publisher
    ..Negative regulation is also not linked to sorting into all LROs but only a specific class of pigment LRO. Thus, regulation of siRNA activity is tied to sorting of specific types of cargo to particular LROs...
  53. Graves A, Moore S, Bloss E, Mensh B, Kath W, Spruston N. Hippocampal pyramidal neurons comprise two distinct cell types that are countermodulated by metabotropic receptors. Neuron. 2012;76:776-89 pubmed publisher
  54. Schwulst S, Trahanas D, Saber R, Perlman H. Traumatic brain injury-induced alterations in peripheral immunity. J Trauma Acute Care Surg. 2013;75:780-8 pubmed publisher
    ..TBI results in temporal changes in both the peripheral and the central immune systems culminating in an overall immune suppressed phenotype and anti-inflammatory milieu. ..
  55. Ng Y, George K, Engel J, Linzer D. GATA factor activity is required for the trophoblast-specific transcriptional regulation of the mouse placental lactogen I gene. Development. 1994;120:3257-66 pubmed
  56. Zhou W, Xu J, Goldberg E. A 60-bp core promoter sequence of murine lactate dehydrogenase C is sufficient to direct testis-specific transcription in vitro. Biol Reprod. 1994;51:425-32 pubmed
    ..A 103-kDa protein in TN and a 65-kDa protein in LN bind to the same palindromic sequences within the 60-bp core promoter region. ..
  57. Horton T, Yellon S. Aging, reproduction, and the melatonin rhythm in the Siberian hamster. J Biol Rhythms. 2001;16:243-53 pubmed
    ..In the wild, failure to undergo testicular regression in the presence of shortening day lengths may extend the breeding season of aged males. ..
  58. Atlas E, Cardillo M, Mehmi I, Zahedkargaran H, Tang C, Lupu R. Heregulin is sufficient for the promotion of tumorigenicity and metastasis of breast cancer cells in vivo. Mol Cancer Res. 2003;1:165-75 pubmed
    ..Our data provide new insights into the mechanisms of breast cancer progression in vivo, and reinforce the important role that HRG plays in this process. ..
  59. Trottier M, Schlitt B, Kung A, Lipton H. Transition from acute to persistent Theiler's virus infection requires active viral replication that drives proinflammatory cytokine expression and chronic demyelinating disease. J Virol. 2004;78:12480-8 pubmed
    ..i. and that active viral replication with high viral genome loads leads to increased levels of Th1 cytokines that drive disease progression in infected mice...
  60. Bristol Gould S, Hutten C, Sturgis C, Kilen S, Mayo K, Woodruff T. The development of a mouse model of ovarian endosalpingiosis. Endocrinology. 2005;146:5228-36 pubmed
    ..A second transgenic mouse model that causes loss of activin action (inhibin alpha-subunit transgenic mice) develops similar cystic structures, supporting a TGF-beta/activin/Smad2 dependence in the onset of this disease. ..
  61. Liu S, Alkema P, Tieche C, Tefft B, Liu D, Li Y, et al. Negative regulation of monocyte adhesion to arterial elastic laminae by signal regulatory protein alpha and Src homology 2 domain-containing protein-tyrosine phosphatase-1. J Biol Chem. 2005;280:39294-301 pubmed
    ..These observations suggest that SIRP alpha and SHP-1 potentially mediate the inhibitory effect of elastic laminae on monocyte adhesion. ..
  62. Siegel J, Cerka A, Recio Spinoso A, Temchin A, van Dijk P, Ruggero M. Delays of stimulus-frequency otoacoustic emissions and cochlear vibrations contradict the theory of coherent reflection filtering. J Acoust Soc Am. 2005;118:2434-43 pubmed
    ..The results for frequencies lower than 4 kHz cannot be explained by hypotheses based on waves propagating to and from their characteristic places in the cochlea...
  63. Bissonnette M, Connolly S, Young D, Randall R, Paterson R, Lamb R. Analysis of the pH requirement for membrane fusion of different isolates of the paramyxovirus parainfluenza virus 5. J Virol. 2006;80:3071-7 pubmed
    ..The challenge of discovering how the paramyxovirus receptor binding protein (HN, H, or G) activates the metastable fusion protein to cause membrane fusion at neutral pH remains. ..
  64. Suszko M, Woodruff T. Cell-specificity of transforming growth factor-beta response is dictated by receptor bioavailability. J Mol Endocrinol. 2006;36:591-600 pubmed
    ..It is likely that the ligand-restricted mechanisms employed by the gonadotrope are present in other cells, which could explain the distinct control of many cellular processes by members of the TGFbeta superfamily. ..
  65. Vitaterna M, Ko C, Chang A, Buhr E, Fruechte E, Schook A, et al. The mouse Clock mutation reduces circadian pacemaker amplitude and enhances efficacy of resetting stimuli and phase-response curve amplitude. Proc Natl Acad Sci U S A. 2006;103:9327-32 pubmed
    ..The increased efficacy of resetting stimuli and decreased PER expression amplitude can be explained in a unified manner by a model in which the Clock mutation reduces circadian pacemaker amplitude in the suprachiasmatic nuclei. ..
  66. Hilgenfeldt S, Erisken S, Carthew R. Physical modeling of cell geometric order in an epithelial tissue. Proc Natl Acad Sci U S A. 2008;105:907-11 pubmed publisher
  67. West Farrell E, Xu M, Gomberg M, Chow Y, Woodruff T, Shea L. The mouse follicle microenvironment regulates antrum formation and steroid production: alterations in gene expression profiles. Biol Reprod. 2009;80:432-9 pubmed publisher
  68. Kirschner A, Sorem J, Longnecker R, Jardetzky T. Structure of Epstein-Barr virus glycoprotein 42 suggests a mechanism for triggering receptor-activated virus entry. Structure. 2009;17:223-33 pubmed publisher
    ..Although the core of the lectin domain remains similar, significant shifts in two loops and an alpha helix bordering the essential hydrophobic pocket suggest a structural mechanism for triggering fusion...
  69. Liu X, Robinson M, Schreiber A, Wu V, Lavail M, Cang J, et al. Regulation of neonatal development of retinal ganglion cell dendrites by neurotrophin-3 overexpression. J Comp Neurol. 2009;514:449-58 pubmed publisher
    ..Taken together, our results suggest that NT-3 and BDNF exhibit overlapping effects in laminar refinement but distinct RGC-cell-type specific effects in shaping dendritic arborization during postnatal development. ..
  70. Lee S, Chen H, O Halloran T, Nguyen S. "Clickable" polymer-caged nanobins as a modular drug delivery platform. J Am Chem Soc. 2009;131:9311-20 pubmed publisher
    ..With both targeting functionalities and pH-sensitive drug-releasing triggers, f-PCN(DXR) was fifty-times more potent than the untargeted agent toward cancer cells that overexpress the folate target receptors. ..
  71. Lu J, Pierce M, Franklin A, Jilling T, Stafforini D, Caplan M. Dual roles of endogenous platelet-activating factor acetylhydrolase in a murine model of necrotizing enterocolitis. Pediatr Res. 2010;68:225-30 pubmed publisher
    ..In conclusion, the data support a protective role for endogenous PAF-AH in the development of NEC, and because preterm neonates have endogenous PAF-AH deficiency, this may place them at increased risk for disease. ..
  72. Kim Y, Spruston N. Target-specific output patterns are predicted by the distribution of regular-spiking and bursting pyramidal neurons in the subiculum. Hippocampus. 2012;22:693-706 pubmed publisher
    ..Variation in the distribution of regular-spiking and bursting neurons suggests that different types of information are conveyed from the subiculum to its various targets. ..
  73. Tang H, Duan C, Bleher R, Goldberg E. Human lactate dehydrogenase A (LDHA) rescues mouse Ldhc-null sperm function. Biol Reprod. 2013;88:96 pubmed publisher
    ..We suggest that it is the localization of the transgene to the sperm cytosol that is mainly responsible for restoration of sperm function and fertility. ..
  74. Raja M, Waterman S, Qiu J, Bleher R, Williamson P, O Halloran T. A copper hyperaccumulation phenotype correlates with pathogenesis in Cryptococcus neoformans. Metallomics. 2013;5:363-71 pubmed publisher
    ..neoformans. ..
  75. Davis Roca A, Muscat C, Wignall S. Caenorhabditis elegans oocytes detect meiotic errors in the absence of canonical end-on kinetochore attachments. J Cell Biol. 2017;216:1243-1253 pubmed publisher
    ..These findings therefore suggest that in this system, kinetochores could be involved in sensing meiotic errors using an unconventional mechanism that does not use canonical end-on attachments. ..
  76. Takahashi J. Circadian clock genes are ticking. Science. 1992;258:238-40 pubmed
  77. Woodruff T, Meunier H, Jones P, Hsueh A, Mayo K. Rat inhibin: molecular cloning of alpha- and beta-subunit complementary deoxyribonucleic acids and expression in the ovary. Mol Endocrinol. 1987;1:561-8 pubmed
    ..Hybridization in situ to rat ovarian tissue demonstrates that both the alpha-inhibin and beta A-inhibin mRNAs are specifically expressed in granulosa cells of the developing follicles. ..
  78. Nakai A, Morimoto R. Characterization of a novel chicken heat shock transcription factor, heat shock factor 3, suggests a new regulatory pathway. Mol Cell Biol. 1993;13:1983-97 pubmed
    ..The HSF3 message, like HSF1 and HSF2 messages, is coexpressed during development and in most tissues, which suggests a general role for the regulatory pathway involving HSF3. ..
  79. Tan S, Bose R, Derrick M. Hypoxia-ischemia in fetal rabbit brain increases reactive nitrogen species production: quantitative estimation of nitrotyrosine. Free Radic Biol Med. 2001;30:1045-51 pubmed
    ..Protein nitrotyrosine was significantly increased following cumulative 40 min ischemia and 20 min reperfusion compared to controls. Repetitive hypoxia-ischemia results in the increased formation of RNS in near-term fetal brains. ..
  80. Schmitt A, Leser G, Waning D, Lamb R. Requirements for budding of paramyxovirus simian virus 5 virus-like particles. J Virol. 2002;76:3952-64 pubmed
    ..Taken together, these data suggest that multiple viral components, including assembled nucleocapsids, have important roles in the paramyxovirus budding process. ..
  81. Cheatham M, Zheng J, Huynh K, Du G, Edge R, Anderson C, et al. Evaluation of an independent prestin mouse model derived from the 129S1 strain. Audiol Neurootol. 2007;12:378-90 pubmed
    ..The linkage shown between the loss of prestin protein and abnormal cochlear function validates the original knockout and attests to the importance of OHC motor function in the auditory periphery. ..
  82. Leonard W. Size counts: evolutionary perspectives on physical activity and body size from early hominids to modern humans. J Phys Act Health. 2010;7 Suppl 3:S284-98 pubmed
    ..These findings highlight the importance of physical activity in promoting nutritional health and show the utility of evolutionary approaches for developing public health recommendations. ..
  83. Huang G, Woolley C. Estradiol acutely suppresses inhibition in the hippocampus through a sex-specific endocannabinoid and mGluR-dependent mechanism. Neuron. 2012;74:801-8 pubmed publisher
    ..Acute E2 modulation of endocannabinoid tone and consequent suppression of inhibition provide a mechanism by which neurosteroid E2 could modulate hippocampus-dependent behaviors in a sex-specific manner. ..
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