Experts and Doctors on zebrafish in Princeton, Florida, United States


Locale: Princeton, Florida, United States
Topic: zebrafish

Top Publications

  1. DeRossi C, Vacaru A, Rafiq R, Cinaroglu A, Imrie D, Nayar S, et al. trappc11 is required for protein glycosylation in zebrafish and humans. Mol Biol Cell. 2016;27:1220-34 pubmed publisher
    ..These data point to a previously unanticipated and conserved role for TRAPPC11 in LLO biosynthesis and protein glycosylation in addition to its established function in vesicle trafficking. ..
  2. Steinberg M. Differential adhesion in morphogenesis: a modern view. Curr Opin Genet Dev. 2007;17:281-6 pubmed
  3. Bally Cuif L, Dubois L, Vincent A. Molecular cloning of Zcoe2, the zebrafish homolog of Xenopus Xcoe2 and mouse EBF-2, and its expression during primary neurogenesis. Mech Dev. 1998;77:85-90 pubmed
    ..At later stages, Zcoe2 is expressed in early forming neurons of the anterior brain and is a marker of the olfactory placodes. ..
  4. Brannen K, Panzica Kelly J, Danberry T, Augustine Rauch K. Development of a zebrafish embryo teratogenicity assay and quantitative prediction model. Birth Defects Res B Dev Reprod Toxicol. 2010;89:66-77 pubmed publisher
    ..The results indicate that this assay is promising for screening compounds for teratogenic potential. Birth Defects Res (Part B) 89:66-77, 2010. (c) 2010 Wiley-Liss, Inc. ..
  5. Ko H, Norman R, Tran J, Fuller K, Fukuda M, Eggenschwiler J. Broad-minded links cell cycle-related kinase to cilia assembly and hedgehog signal transduction. Dev Cell. 2010;18:237-47 pubmed publisher
    ..We propose that Bromi and CCRK control the structure of the primary cilium by coordinating assembly of the axoneme and ciliary membrane, allowing Gli proteins to be properly activated in response to Shh signaling. ..
  6. Howley C, Ho R. mRNA localization patterns in zebrafish oocytes. Mech Dev. 2000;92:305-9 pubmed
    ..Unique patterns of localization are seen in mature eggs as well. Some mRNAs maintain their oocyte localization patterns, while others localize upon egg activation (fertilization). ..
  7. Schottenfeld J, Sullivan Brown J, Burdine R. Zebrafish curly up encodes a Pkd2 ortholog that restricts left-side-specific expression of southpaw. Development. 2007;134:1605-15 pubmed
    ..pkd2 also appears to play a role in the propagation of Nodal signals in the LPM. Based on morpholino studies, we propose an additional role for maternal pkd2 in general mesendoderm patterning. ..
  8. Oates A, Ho R. Hairy/E(spl)-related (Her) genes are central components of the segmentation oscillator and display redundancy with the Delta/Notch signaling pathway in the formation of anterior segmental boundaries in the zebrafish. Development. 2002;129:2929-46 pubmed
    ..Furthermore, our data suggest that redundancy between Her genes and genes of the Delta/Notch pathway is in part responsible for the robust formation of anterior somites in vertebrates. ..
  9. Baker K, Holtzman N, Burdine R. Direct and indirect roles for Nodal signaling in two axis conversions during asymmetric morphogenesis of the zebrafish heart. Proc Natl Acad Sci U S A. 2008;105:13924-9 pubmed publisher
    ..These results suggest that Nodal signaling directs asymmetric cardiac morphogenesis through establishing and subsequently reinforcing laterality information over the course of cardiac development. ..

More Information


  1. Manning M, Foty R, Steinberg M, Schoetz E. Coaction of intercellular adhesion and cortical tension specifies tissue surface tension. Proc Natl Acad Sci U S A. 2010;107:12517-22 pubmed publisher
    ..This model indicates that there is a crossover from adhesion dominated to cortical-tension dominated behavior as a function of the ratio between these two quantities. ..
  2. Lenhart K, Lin S, Titus T, Postlethwait J, Burdine R. Two additional midline barriers function with midline lefty1 expression to maintain asymmetric Nodal signaling during left-right axis specification in zebrafish. Development. 2011;138:4405-10 pubmed publisher
    ..Both barriers appear to be conserved across model systems and are thus likely to be present in all vertebrates. ..
  3. Fuller K, O Connell J, Gordon J, Mauti O, EGGENSCHWILER J. Rab23 regulates Nodal signaling in vertebrate left-right patterning independently of the Hedgehog pathway. Dev Biol. 2014;391:182-95 pubmed publisher
    ..Collectively, these data suggest that Rab23 is an essential component of the mechanism that transmits asymmetric patterning information from the node to the LPM. ..
  4. Jaffe K, Grimes D, Schottenfeld Roames J, Werner M, Ku T, Kim S, et al. c21orf59/kurly Controls Both Cilia Motility and Polarization. Cell Rep. 2016;14:1841-9 pubmed publisher
    ..Kur also makes interactions with other PCP components, including Disheveled. This supports a model wherein Kur plays a dual role in cilia motility and polarization. ..
  5. Bally Cuif L, Schatz W, Ho R. Characterization of the zebrafish Orb/CPEB-related RNA binding protein and localization of maternal components in the zebrafish oocyte. Mech Dev. 1998;77:31-47 pubmed
    ..We show that this localization is independent of microtubules and microfilaments, and that the distribution of Zorba protein parallels that of its mRNA. ..
  6. Oates A, Rohde L, Ho R. Generation of segment polarity in the paraxial mesoderm of the zebrafish through a T-box-dependent inductive event. Dev Biol. 2005;283:204-14 pubmed
  7. Sullivan Brown J, Schottenfeld J, Okabe N, Hostetter C, Serluca F, Thiberge S, et al. Zebrafish mutations affecting cilia motility share similar cystic phenotypes and suggest a mechanism of cyst formation that differs from pkd2 morphants. Dev Biol. 2008;314:261-75 pubmed publisher
    ..Finally, we show that knock-down of polycystic kidney disease 2 (pkd2) specifically causes glomerular cysts and does not affect cilia motility, suggesting multiple mechanisms exist for cyst formation. ..
  8. Ahn D, Ruvinsky I, Oates A, Silver L, Ho R. tbx20, a new vertebrate T-box gene expressed in the cranial motor neurons and developing cardiovascular structures in zebrafish. Mech Dev. 2000;95:253-8 pubmed
    ..During development, tbx20 is expressed in embryonic structures of both mesodermal and ectodermal origins, including the heart, cranial motor neurons, and the roof of the dorsal aorta. ..
  9. Mora T, Walczak A, Bialek W, Callan C. Maximum entropy models for antibody diversity. Proc Natl Acad Sci U S A. 2010;107:5405-10 pubmed publisher
    ..This approach should be applicable to the study of the global properties of other protein families. ..