Experts and Doctors on xenopus laevis in Princeton, Florida, United States
Locale: Princeton, Florida, United States
Topic: xenopus laevis
Feric M, Vaidya N, Harmon T, Mitrea D, Zhu L, Richardson T, et al
. Coexisting Liquid Phases Underlie Nucleolar Subcompartments. Cell. 2016;165:1686-1697 pubmed publisher
..These results suggest that phase separation can give rise to multilayered liquids that may facilitate sequential RNA processing reactions in a variety of RNP bodies. PAPERCLIP. ..
Shalaby F, Levesque P, Yang W, Little W, Conder M, Jenkins West T, et al
. Dominant-negative KvLQT1 mutations underlie the LQT1 form of long QT syndrome. Circulation. 1997;96:1733-6 pubmed
..In LQTS-affected individuals these mutations would be predicted to result in a diminution of the cardiac I(Ks) current, subsequent prolongation of cardiac repolarization, and an increased risk of arrhythmias. ..
Zhang Z, Lee Y, Rhodes K, Wang K, Argentieri T, Wang Q. Inhibitory effects of pimozide on cloned and native voltage-gated potassium channels. Brain Res Mol Brain Res. 2003;115:29-38 pubmed
..It is thus conceivable that the time-dependent and/or subunit-specific inhibition of Kv channels may increase the release of neurotransmitters such as serotonin and glutamate. ..
Brangwynne C. Phase transitions and size scaling of membrane-less organelles. J Cell Biol. 2013;203:875-81 pubmed publisher
..This size scaling could, in turn, play a role in cell growth and size control. ..
Cheng Y, Woolf T, Gan J, He K. InÂ vitro model systems to investigate bile salt export pump (BSEP) activity and drug interactions: A review. Chem Biol Interact. 2016;255:23-30 pubmed publisher
..The use of pooled cryopreserved hepatocytes in suspension minimizes genetic variance and individual differences in BSEP activity and also provides the opportunity for higher throughput screening and cross-species comparisons. ..
Jaffe K, Grimes D, Schottenfeld Roames J, Werner M, Ku T, Kim S, et al
. c21orf59/kurly Controls Both Cilia Motility and Polarization. Cell Rep. 2016;14:1841-9 pubmed publisher
..Kur also makes interactions with other PCP components, including Disheveled. This supports a model wherein Kur plays a dual role in cilia motility and polarization. ..
Alfaro Aco R, Thawani A, Petry S. Structural analysis of the role of TPX2 in branching microtubule nucleation. J Cell Biol. 2017;216:983-997 pubmed publisher
..Separation-of-function mutations leave the binding of TPX2 to ?-TuRC intact, whereas branching MT nucleation is abolished, suggesting that TPX2 may activate ?-TuRC to promote branching MT nucleation. ..