Experts and Doctors on rna binding proteins in University Park, Florida, United States

Summary

Locale: University Park, Florida, United States
Topic: rna binding proteins

Top Publications

  1. Guiltinan M, Niu X. cDNA encoding a wheat (Triticum aestivum cv. Chinese spring) glycine-rich RNA-binding protein. Plant Mol Biol. 1996;30:1301-6 pubmed
  2. Baker C, Morozov I, Suzuki K, Romeo T, Babitzke P. CsrA regulates glycogen biosynthesis by preventing translation of glgC in Escherichia coli. Mol Microbiol. 2002;44:1599-610 pubmed
    ..This inhibition of translation probably contributes to destabilization of the glgC transcript that was observed previously...
  3. Cui L, Fan Q, Li J. The malaria parasite Plasmodium falciparum encodes members of the Puf RNA-binding protein family with conserved RNA binding activity. Nucleic Acids Res. 2002;30:4607-17 pubmed
    ..Altogether, these results suggest that PfPufs might function during sexual differentiation and development in Plasmodium through a conserved mechanism of translational regulation of their target mRNAs. ..
  4. Hong S, Tran Q, Keiler K. Cell cycle-regulated degradation of tmRNA is controlled by RNase R and SmpB. Mol Microbiol. 2005;57:565-75 pubmed publisher
    ..This model explains the regulation of SsrA RNA in other bacteria, and suggests that a highly conserved regulatory mechanism controls SsrA activity...
  5. Dubey A, Baker C, Romeo T, Babitzke P. RNA sequence and secondary structure participate in high-affinity CsrA-RNA interaction. RNA. 2005;11:1579-87 pubmed
    ..A mutational analysis of one selected ligand confirmed that the conserved ACA, GGA, and GU residues were critical for CsrA binding and that RNA secondary structure participates in CsrA-RNA recognition. ..
  6. Yakhnin H, Yakhnin A, Babitzke P. The trp RNA-binding attenuation protein (TRAP) of Bacillus subtilis regulates translation initiation of ycbK, a gene encoding a putative efflux protein, by blocking ribosome binding. Mol Microbiol. 2006;61:1252-66 pubmed publisher
    ..We also identified two dipeptide coding minigenes between the Shine-Dalgarno sequence and start codon of ycbK. Expression of one of the minigenes modestly interfered with translation of ycbK...
  7. Yakhnin H, Pandit P, Petty T, Baker C, Romeo T, Babitzke P. CsrA of Bacillus subtilis regulates translation initiation of the gene encoding the flagellin protein (hag) by blocking ribosome binding. Mol Microbiol. 2007;64:1605-20 pubmed publisher
    ..Toeprint and cell-free translation studies demonstrate that bound CsrA prevents ribosome binding to the hag transcript, thereby inhibiting translation initiation and Hag synthesis...
  8. Dong Z, Han M, Fedoroff N. The RNA-binding proteins HYL1 and SE promote accurate in vitro processing of pri-miRNA by DCL1. Proc Natl Acad Sci U S A. 2008;105:9970-5 pubmed publisher
    ..We show that recombinant HYL1 and SE proteins accelerate the rate of DCL1-mediated cleavage of pre- and pri-miR167b substrates and promote accurate processing. ..
  9. Kim C, Bove J, Assmann S. Overexpression of wound-responsive RNA-binding proteins induces leaf senescence and hypersensitive-like cell death. New Phytol. 2008;180:57-70 pubmed publisher
    ..These results indicate that induction of UBA2 gene expression stimulates leaf yellowing and cell death phenotypes through senescence and defense response pathways. ..

More Information

Publications14

  1. Russell J, Keiler K. Subcellular localization of a bacterial regulatory RNA. Proc Natl Acad Sci U S A. 2009;106:16405-9 pubmed publisher
    ..These results suggest a model in which tmRNA-SmpB is localized to sequester tmRNA from RNase R, and localization might also regulate tmRNA-SmpB interactions with ribosomes...
  2. Miao J, Li J, Fan Q, Li X, Li X, Cui L. The Puf-family RNA-binding protein PfPuf2 regulates sexual development and sex differentiation in the malaria parasite Plasmodium falciparum. J Cell Sci. 2010;123:1039-49 pubmed publisher
    ..These findings suggest that in this early branch of eukaryotes the function of PfPuf2 is consistent with the ancestral function of suppressing differentiation proposed for Puf-family proteins...
  3. Song L, Han M, Lesicka J, Fedoroff N. Arabidopsis primary microRNA processing proteins HYL1 and DCL1 define a nuclear body distinct from the Cajal body. Proc Natl Acad Sci U S A. 2007;104:5437-42 pubmed
    ..Thus, the distinct HYL1- and DCL1-containing nuclear bodies may be miRNA precursor processing sites. Alternatively, they may be assembly and storage sites for the miRNA precursor processing machinery...
  4. Baker C, Eöry L, Yakhnin H, Mercante J, Romeo T, Babitzke P. CsrA inhibits translation initiation of Escherichia coli hfq by binding to a single site overlapping the Shine-Dalgarno sequence. J Bacteriol. 2007;189:5472-81 pubmed
    ..The interaction of CsrA with hfq mRNA is the first example of a CsrA-regulated gene that contains only one CsrA binding site. ..
  5. Bove J, Kim C, Gibson C, Assmann S. Characterization of wound-responsive RNA-binding proteins and their splice variants in Arabidopsis. Plant Mol Biol. 2008;67:71-88 pubmed publisher
    ..Taken together, these results imply that the three UBA2 genes encode hnRNP-type nuclear RNA-binding proteins that function in a novel wound signal transduction pathway. ..