Genomes and Genes
Experts and Doctors on molecular sequence data in University Park, Florida, United States
Locale: University Park, Florida, United States
Topic: molecular sequence data
- Marolewski A, Smith J, Benkovic S. Cloning and characterization of a new purine biosynthetic enzyme: a non-folate glycinamide ribonucleotide transformylase from E. coli. Biochemistry. 1994;33:2531-7 pubmed..The purT GAR transformylase is the first unknown de novo purine biosynthetic enzyme to be discovered in the last 30 years and represents another step forward in understanding cellular control of purine levels. ..
- Hua Z, Kao T. Identification and characterization of components of a putative petunia S-locus F-box-containing E3 ligase complex involved in S-RNase-based self-incompatibility. Plant Cell. 2006;18:2531-53 pubmed..Finally, S-RNases are ubiquitinated in pollen tube extracts, but whether this is mediated by the Pi SLF-containing E3 complex is unknown. ..
- Zhuang H, Patel S, He T, Sonsteby S, Niu Z, Wojchowski D. Inhibition of erythropoietin-induced mitogenesis by a kinase-deficient form of Jak2. J Biol Chem. 1994;269:21411-4 pubmed..These dominant-negative effects provide the first direct experimental evidence for an essential role for Janus kinase activation in mitogenesis and suggest that distinct effectors may mediate IL-3-induced versus Epo-induced pathways. ..
- Chiu P, Chaudhuri S, Harding P, Kopchick J, Donkin S, Etherton T. Cloning of a pig glucose transporter 4 cDNA fragment: use in developing a sensitive ribonuclease protection assay for quantifying low-abundance glucose transporter 4 mRNA in porcine adipose tissue. J Anim Sci. 1994;72:1196-203 pubmed
- Purnell B, Emanuel P, Gilmour D. TFIID sequence recognition of the initiator and sequences farther downstream in Drosophila class II genes. Genes Dev. 1994;8:830-42 pubmed..Selection of this sequence demonstrates that sequence-specific interactions downstream of the TATA element contribute to the interaction of TFIID on a wide spectrum of promoters. ..
- Schmitt P, Ray G, Schmitt A. The C-terminal end of parainfluenza virus 5 NP protein is important for virus-like particle production and M-NP protein interaction. J Virol. 2010;84:12810-23 pubmed publisher..These results suggest that multiple avenues are available to paramyxoviruses for overcoming defects in M-NP protein interaction...
- Levitt A, Singh R, Cox Foster D, Rajotte E, Hoover K, Ostiguy N, et al. Cross-species transmission of honey bee viruses in associated arthropods. Virus Res. 2013;176:232-40 pubmed publisher..In sum, our study indicates that these viruses are not specific to the pollinator community and that other arthropod species have the potential to be involved in disease transmission in pollinator populations...
- Schluchter W, Bryant D. Molecular characterization of ferredoxin-NADP+ oxidoreductase in cyanobacteria: cloning and sequence of the petH gene of Synechococcus sp. PCC 7002 and studies on the gene product. Biochemistry. 1992;31:3092-102 pubmed..Smaller cross-reactive species in the mass range 24-35 kDa appear to be proteolytic degradation products. ..
- Richards C, Hinman S, Boyer C, Hardison R. Survey of plastid RNA abundance during tomato fruit ripening: the amounts of RNA from the ORF 2280 region increase in chromoplasts. Plant Mol Biol. 1991;17:1179-88 pubmed..The large RNA from the P7 region may encode a protein that functions predominantly in chromoplasts. ..
- Toung Y, Hsieh T, Tu C. The Drosophila glutathione S-transferase 1-1 is encoded by an intronless gene at 87B. Biochem Biophys Res Commun. 1991;178:1205-11 pubmed..We report that the glutathione S-transferase activity in Kco cells as determined by conjugation with 1-chloro-2,4-dinitrobenzene is elevated slightly to two-fold under heat shock. The implication of this finding is discussed. ..
- Rhodes M, Spear J, Oren A, House C. Differences in lateral gene transfer in hypersaline versus thermal environments. BMC Evol Biol. 2011;11:199 pubmed publisher..Furthermore, most hypersaline environments, as topographical minima, are natural collectors of cellular debris. Thus halophiles would in theory be exposed to a greater diversity and quantity of extracellular DNA than thermophiles. ..
- Nallagatla S, Hwang J, Toroney R, Zheng X, Cameron C, Bevilacqua P. 5'-triphosphate-dependent activation of PKR by RNAs with short stem-loops. Science. 2007;318:1455-8 pubmed..The evidence presented here suggests that this form of RNA-based discrimination may be a critical step in mounting an early immune response. ..
- McNeil J, Cox Foster D, Gardner M, Slavicek J, Thiem S, Hoover K. Pathogenesis of Lymantria dispar multiple nucleopolyhedrovirus in L. dispar and mechanisms of developmental resistance. J Gen Virol. 2010;91:1590-600 pubmed publisher..This age-related susceptibility may contribute to how the virus is maintained in nature and could influence management of L. dispar by using the virus...
- Beal E, House C, Orphan V. Manganese- and iron-dependent marine methane oxidation. Science. 2009;325:184-7 pubmed publisher..Large amounts of manganese and iron are provided to oceans from rivers, indicating that manganese- and iron-dependent AOM have the potential to be globally important...
- Loveland Curtze J, Miteva V, Brenchley J. Herminiimonas glaciei sp. nov., a novel ultramicrobacterium from 3042 m deep Greenland glacial ice. Int J Syst Evol Microbiol. 2009;59:1272-7 pubmed publisher..nov. is proposed. The type strain is UMB49(T) (=ATCC BAA-1623(T)=DSM 21140(T)). ..
- Toung Y, Hsieh T, Tu C. The glutathione S-transferase D genes. A divergently organized, intronless gene family in Drosophila melanogaster. J Biol Chem. 1993;268:9737-46 pubmed..The gst D genes in other organisms should be intronless and can be isolated directly from genomic DNAs for functional analyses at the gene and protein levels. ..
- Wang Y, Wang X, McCubbin A, Kao T. Genetic mapping and molecular characterization of the self-incompatibility (S) locus in Petunia inflata. Plant Mol Biol. 2003;53:565-80 pubmed..In contrast to S-RNase, all these genes showed very low degrees of allelic sequence diversity in the coding regions, introns, and flanking regions...
- Smith K, Ferry J. Prokaryotic carbonic anhydrases. FEMS Microbiol Rev. 2000;24:335-66 pubmed..Investigations into prokaryotic carbonic anhydrase have already led to the identification of a new class (gamma) and future research will undoubtedly reveal novel functions for carbonic anhydrase in prokaryotes. ..
- Dattagupta S, Schaperdoth I, Montanari A, Mariani S, Kita N, Valley J, et al. A novel symbiosis between chemoautotrophic bacteria and a freshwater cave amphipod. ISME J. 2009;3:935-43 pubmed publisher..Therefore, the N. ictus-Thiothrix symbiosis is probably significantly younger than marine chemoautotrophic symbioses, many of which have been evolving for tens to hundreds of million years. ..
- Tollersrud O, Aronson N. Comparison of liver glycosylasparaginases from six vertebrates. Biochem J. 1992;282 ( Pt 3):891-7 pubmed..5 and 6 except for the rat and mouse enzymes which had a broad maximum between pH 7 and 8. A number of other properties were observed which also distinguish the enzyme from individual and closely related species. ..
- Boyd E, Nelson K, Wang F, Whittam T, Selander R. Molecular genetic basis of allelic polymorphism in malate dehydrogenase (mdh) in natural populations of Escherichia coli and Salmonella enterica. Proc Natl Acad Sci U S A. 1994;91:1280-4 pubmed
- Zhang W, Sun Y, Timofejeva L, Chen C, Grossniklaus U, Ma H. Regulation of Arabidopsis tapetum development and function by DYSFUNCTIONAL TAPETUM1 (DYT1) encoding a putative bHLH transcription factor. Development. 2006;133:3085-95 pubmed..Our results support the hypothesis that DYT1 is a crucial component of a genetic network that controls anther development and function. ..
- Perederina A, Esakova O, Quan C, Khanova E, Krasilnikov A. Eukaryotic ribonucleases P/MRP: the crystal structure of the P3 domain. EMBO J. 2010;29:761-9 pubmed publisher..It provides the first insight into the structural organization of the eukaryotic enzymes of the RNase P/MRP family. ..
- Davis R, Lecomte J. Structural propensities in the heme binding region of apocytochrome b5. I. Free peptides. Biopolymers. 2008;90:544-55 pubmed publisher..It was concluded that the prediction of intrinsic disorder was reliable. Furthermore, the stability of the holoprotein did not correlate simply with helical propensities in the disordered regions. ..
- Cui L, Cheng X, Li L, Li J. Identification of Trichoplusia ni ascovirus 2c virion structural proteins. J Gen Virol. 2007;88:2194-7 pubmed..e. ORFs 2, 43, 115, 141, 142, 147 and 153. Among these ORFs, only ORF153, encoding the major capsid protein, has been characterized previously...
- Schaeffer S, Miller E. Nucleotide sequence analysis of Adh genes estimates the time of geographic isolation of the Bogota population of Drosophila pseudoobscura. Proc Natl Acad Sci U S A. 1991;88:6097-101 pubmed..This divergence time suggests that D. pseudoobscura extended its range from North America to South America in a period of Pleistocene glaciation, when habitat suitable for the species presumably existed in lowland Central America...
- Fisher D, Gao M, Kim K, Boyer C, Guiltinan M. Two closely related cDNAs encoding starch branching enzyme from Arabidopsis thaliana. Plant Mol Biol. 1996;30:97-108 pubmed..This is the first report of the identification of cDNAs encoding two closely related starch branching enzymes from the same species. ..
- Melkun E, Pilione M, Paulson R. A naturally occurring point substitution in Cdc25A, and not Fv2/Stk, is associated with altered cell-cycle status of early erythroid progenitor cells. Blood. 2002;100:3804-11 pubmed..Furthermore, overexpression of Cdc25A in bone marrow cells causes a defect in the BFU-E colony formation. These results suggest that proper regulation of the cell cycle through Cdc25A is required for normal erythropoiesis. ..
- Moyer M, Gilbert S, Johnson K. Purification and characterization of two monomeric kinesin constructs. Biochemistry. 1996;35:6321-9 pubmed
- Zolfaghari R, Wang Y, Chen Q, Sancher A, Ross A. Cloning and molecular expression analysis of large and small lecithin:retinol acyltransferase mRNAs in the liver and other tissues of adult rats. Biochem J. 2002;368:621-31 pubmed..The differential usage of these polyadenylation signals can explain the presence of multiple LRAT mRNA transcripts which are expressed in different tissue-specific patterns. ..
- Dahlberg M, Benkovic S. Kinetic mechanism of DNA polymerase I (Klenow fragment): identification of a second conformational change and evaluation of the internal equilibrium constant. Biochemistry. 1991;30:4835-43 pubmed..The combination of the experimentally measured equilibrium constant for the bound KF.DNA species with the collective kinetic measurements further extends previous insights into the dynamics of the polymerization process catalyzed by KF. ..
- Garofalo A, Kl ger S, Rowlinson M, Nirmalan N, Klion A, Allen J, et al. The FAR proteins of filarial nematodes: secretion, glycosylation and lipid binding characteristics. Mol Biochem Parasitol. 2002;122:161-70 pubmed
- Margot J, Demers G, Hardison R. Complete nucleotide sequence of the rabbit beta-like globin gene cluster. Analysis of intergenic sequences and comparison with the human beta-like globin gene cluster. J Mol Biol. 1989;205:15-40 pubmed..Sequences far removed from the gene are evolving at a rate equivalent to the pseudogene rate, although some short regions show an apparently higher rate.(ABSTRACT TRUNCATED AT 400 WORDS) ..
- Zhang Z, Buchman A. Identification of a member of a DNA-dependent ATPase family that causes interference with silencing. Mol Cell Biol. 1997;17:5461-72 pubmed..These results suggest that DIS1 may contribute to making the silenced DNA template at HM loci more accessible during the mating-type switching process. ..
- Perederina A, Khanova E, Quan C, Berezin I, Esakova O, Krasilnikov A. Interactions of a Pop5/Rpp1 heterodimer with the catalytic domain of RNase MRP. RNA. 2011;17:1922-31 pubmed publisher..The Pop5/Rpp1 binding site corresponds to the protein binding site in bacterial RNase P RNA. Structural and evolutionary roles of the Pop5/Rpp1 heterodimer in RNases P and MRP are discussed. ..
- Nekrutenko A, He J. Functionality of unspliced XBP1 is required to explain evolution of overlapping reading frames. Trends Genet. 2006;22:645-8 pubmed..Our study provides a novel evolutionary framework for the analysis of loci with overlapping reading frames, which can be used for identification and analyses of novel dual-coding genes. ..
- Gregory R, Lord K, Panek L, Gaines P, Dillon S, Wojchowski D. Subtraction cloning and initial characterization of novel epo-immediate response genes. Cytokine. 2000;12:845-57 pubmed..Thus, several new Epo signalling targets are described, which may modulate haematopoietic cell development. ..
- Grant P, Schieltz D, Pray Grant M, Yates J, Workman J. The ATM-related cofactor Tra1 is a component of the purified SAGA complex. Mol Cell. 1998;2:863-7 pubmed..These results indicate a role for Tra1 in the regulation of transcriptional activation through the recruitment of HAT activity to an activator-bound promoter. ..
- Hu L, Allison S, Phillips A. Identification of multiple repressor recognition sites in the hut system of Pseudomonas putida. J Bacteriol. 1989;171:4189-95 pubmed..A roughly 40-base-pair portion was identified which contained a 16-base-pair region of dyad symmetry located near the transcription initiation site for this operon. ..
- Zuo Y, Xing D, Regan J, Logan B. Isolation of the exoelectrogenic bacterium Ochrobactrum anthropi YZ-1 by using a U-tube microbial fuel cell. Appl Environ Microbiol. 2008;74:3130-7 pubmed publisher..Further applications of this new U-tube MFC system should provide a method for obtaining additional exoelectrogenic microorganisms that do not necessarily require metal oxides for cell respiration...
- Walter P, Owen Hughes T, Cote J, Workman J. Stimulation of transcription factor binding and histone displacement by nucleosome assembly protein 1 and nucleoplasmin requires disruption of the histone octamer. Mol Cell Biol. 1995;15:6178-87 pubmed..Thus, histone displacement in this instance occurred by transfer of complete histone octamers, a mechanism distinct from that mediated by the histone-binding proteins nucleoplasmin and NAP-1. ..
- Aronson N, Kuranda M. Lysosomal degradation of Asn-linked glycoproteins. FASEB J. 1989;3:2615-22 pubmed..The species that lack this enzyme likely rely on exo-beta-D-glucosaminidase to cleave GlcNAc from both outer chain residues and the chitobiose moiety at the protein-to-carbohydrate linkage. ..
- Doerfert S, Reichlen M, Iyer P, Wang M, Ferry J. Methanolobus zinderi sp. nov., a methylotrophic methanogen isolated from a deep subsurface coal seam. Int J Syst Evol Microbiol. 2009;59:1064-9 pubmed publisher..It is proposed that strain SD1(T) represents a novel species, Methanolobus zinderi sp. nov. The type strain is SD1(T) (=ATCC BAA-1601(T)=DSM 21339(T))...
- Maupin Furlow J, Ferry J. A proteasome from the methanogenic archaeon Methanosarcina thermophila. J Biol Chem. 1995;270:28617-22 pubmed..The results suggest that proteasomes are more widespread in the Archaea than previously proposed. Southern blotting experiments suggested the presence of ubiquitin-like sequences in M. thermophila. ..
- Tollersrud O, Aronson N. Purification and characterization of rat liver glycosylasparaginase. Biochem J. 1989;260:101-8 pubmed..5. The enzyme exhibited a broad pH maximum above 7. Two major isoelectric forms were found at pH 6.4 and 6.6. 6. Glycosylasparaginase was stable at 75 degrees C and in 5% (w/v) SDS at pH 7.0. ..
- Borup B, Ferry J. O-Acetylserine sulfhydrylase from Methanosarcina thermophila. J Bacteriol. 2000;182:45-50 pubmed..The results also provide the first biochemical evidence for an enzyme with the potential for involvement in cysteine biosynthesis in the Archaea...
- Shi Z, Zhang Y, Maximova S, Guiltinan M. TcNPR3 from Theobroma cacao functions as a repressor of the pathogen defense response. BMC Plant Biol. 2013;13:204 pubmed publisher..This novel knowledge can contribute to the breeding of resistant cacao varieties against pathogens through molecular markers based approaches or biotechnological strategies...
- Axtell M, Snyder J, Bartel D. Common functions for diverse small RNAs of land plants. Plant Cell. 2007;19:1750-69 pubmed..Diverse, lineage-specific, small RNAs can therefore perform common biological functions in plants...
- Bell D, Plant N, Rider C, Na L, Brown S, Ateitalla I, et al. Species-specific induction of cytochrome P-450 4A RNAs: PCR cloning of partial guinea-pig, human and mouse CYP4A cDNAs. Biochem J. 1993;294 ( Pt 1):173-80 pubmed..These findings are consistent with a species difference in response to peroxisome proliferators between the rat/mouse and the guinea pig...
- Hao L, Nei M. Rapid expansion of killer cell immunoglobulin-like receptor genes in primates and their coevolution with MHC Class I genes. Gene. 2005;347:149-59 pubmed..The rate of expansion of this gene family seems to be one of the highest among all hominoid gene families. The KIR gene family is also subject to birth-and-death evolution. ..
- Arner R, Prabhu K, Reddy C. Molecular cloning, expression, and characterization of myo-inositol oxygenase from mouse, rat, and human kidney. Biochem Biophys Res Commun. 2004;324:1386-92 pubmed..Regardless of the source, our results strongly dispel previous conflicting literature reports on the size of the protein and confirm that MIOX is a 33kDa protein. ..
- Boyd E, Li J, Ochman H, Selander R. Comparative genetics of the inv-spa invasion gene complex of Salmonella enterica. J Bacteriol. 1997;179:1985-91 pubmed
- Chang T, Yang Y, Retzel E, Liu W. Male-specific region of the bovine Y chromosome is gene rich with a high transcriptomic activity in testis development. Proc Natl Acad Sci U S A. 2013;110:12373-8 pubmed publisher..The massive amplification and vigorous transcription suggest that the MSY serves as a genomic niche regulating male reproduction during bovid expansion...
- Zhang H, Bruns M, Logan B. Perchlorate reduction by a novel chemolithoautotrophic, hydrogen-oxidizing bacterium. Environ Microbiol. 2002;4:570-6 pubmed..The study of this and other novel perchlorate-reducing bacteria may lead to new, safe technologies for removing perchlorate and other chemical pollutants from drinking water...
- Han M, Cimen H, Miller Lee J, Koc H, Koc E. Purification of human mitochondrial ribosomal L7/L12 stalk proteins and reconstitution of functional hybrid ribosomes in Escherichia coli. Protein Expr Purif. 2011;78:48-54 pubmed publisher..The goal is to demonstrate the homology between the mitochondrial and bacterial L7/L12 stalk proteins and to reconstitute a hybrid ribosome to be used in structural and functional studies of the mitochondrial stalk. ..
- Martinson A, van Rossum D, Diatta F, Layden M, Rhodes S, Martindale M, et al. Functional evolution of Erg potassium channel gating reveals an ancient origin for IKr. Proc Natl Acad Sci U S A. 2014;111:5712-7 pubmed publisher..This domain is required for slow deactivation in mammalian Erg1 channels, and thus its loss may partially explain the change in gating phenotype. ..
- Iyer P, Geib S, Catchmark J, Kao T, Tien M. Genome sequence of a cellulose-producing bacterium, Gluconacetobacter hansenii ATCC 23769. J Bacteriol. 2010;192:4256-7 pubmed publisher..The Gram-negative bacterium Gluconacetobacter hansenii is considered a model organism for studying cellulose synthesis. We have determined the genome sequence of strain ATCC 23769...
- Plumridge A, Melin P, Stratford M, Novodvorska M, Shunburne L, Dyer P, et al. The decarboxylation of the weak-acid preservative, sorbic acid, is encoded by linked genes in Aspergillus spp. Fungal Genet Biol. 2010;47:683-92 pubmed publisher..This cluster is absent from the genomes of A. fumigatus and A. clavatus and, as a consequence, neither species is capable of decarboxylating sorbic acid. ..
- Yakhnin H, Baker C, Berezin I, Evangelista M, Rassin A, Romeo T, et al. CsrA represses translation of sdiA, which encodes the N-acylhomoserine-L-lactone receptor of Escherichia coli, by binding exclusively within the coding region of sdiA mRNA. J Bacteriol. 2011;193:6162-70 pubmed publisher..Thus, this represents the first example of CsrA preventing translation by interacting solely within the coding region of an mRNA target. ..
- Xie K, Yang Y. RNA-guided genome editing in plants using a CRISPR-Cas system. Mol Plant. 2013;6:1975-83 pubmed publisher..Our results demonstrate that the CRISPR-Cas system can be exploited as a powerful tool for gene targeting and precise genome editing in plants. ..
- Kasson M, O Donnell K, Rooney A, Sink S, Ploetz R, Ploetz J, et al. An inordinate fondness for Fusarium: phylogenetic diversity of fusaria cultivated by ambrosia beetles in the genus Euwallacea on avocado and other plant hosts. Fungal Genet Biol. 2013;56:147-57 pubmed publisher..Overall, these data are consistent with a strong evolutionary trend toward obligate symbiosis coupled with secondary contact and interspecific hybridization. ..
- Gilmour D, Fan R. Detecting transcriptionally engaged RNA polymerase in eukaryotic cells with permanganate genomic footprinting. Methods. 2009;48:368-74 pubmed publisher..The method should prove useful in assessing if promoter bound Pol II has engaged in transcription and for investigating the establishment and regulation of transcriptionally engaged Pol II. ..
- Gruber T, Eisen J, Gish K, Bryant D. The phylogenetic relationships of Chlorobium tepidum and Chloroflexus aurantiacus based upon their RecA sequences. FEMS Microbiol Lett. 1998;162:53-60 pubmed..Cf. aurantiacus was placed near Chlamydia trachomatis and the high-GC Gram-positives; however, this branching pattern was not strongly supported statistically by bootstrap analyses. Possible reasons for this ambiguity are discussed...
- Seufert D, Kos R, Erickson C, Swalla B. p68, a DEAD-box RNA helicase, is expressed in chordate embryo neural and mesodermal tissues. J Exp Zool. 2000;288:193-204 pubmed..Further functional experiments will be necessary to understand the role(s) p68 may play in vertebrate development. ..
- Maupin Furlow J, Ferry J. Characterization of the cdhD and cdhE genes encoding subunits of the corrinoid/iron-sulfur enzyme of the CO dehydrogenase complex from Methanosarcina thermophila. J Bacteriol. 1996;178:340-6 pubmed..The purified CdhE protein exhibited an Fe-S center and base-off cobalamin binding in which the benzimidazole base nitrogen atom was no longer a lower axial ligand to the cobalt atom...
- Lee H, Tu C. Drosophila glutathione S-transferase D27: functional analysis of two consecutive tyrosines near the N-terminus. Biochem Biophys Res Commun. 1995;209:327-34 pubmed..Results from in vitro biochemical analyses were confirmed by the in vivo activity-based CDNB growth inhibition analyses. Our results clearly indicate that the Drosophila GST D isozymes are different from any of the known mammalian GSTs. ..
- Ni S, Zhao C, Feng G, Paulson R, Correll P. A novel Stat3 binding motif in Gab2 mediates transformation of primary hematopoietic cells by the Stk/Ron receptor tyrosine kinase in response to Friend virus infection. Mol Cell Biol. 2007;27:3708-15 pubmed
- Sato S, Liu F, Koc H, Tien M. Expression analysis of extracellular proteins from Phanerochaete chrysosporium grown on different liquid and solid substrates. Microbiology. 2007;153:3023-33 pubmed..In addition to enzymes which act on lignocellulosic material, proteases were also found, indicating the need of fungi to scavenge for nitrogen in wood...
- Liu K, Knabel S, Dudley E. rhs genes are potential markers for multilocus sequence typing of Escherichia coli O157:H7 strains. Appl Environ Microbiol. 2009;75:5853-62 pubmed publisher..Additionally, unique markers were found in rhsA and rhsJ that might be used to define clade 8 and clade 6. Therefore, rhs genes may be useful markers for phylogenetic analysis of E. coli O157:H7. ..
- Yakhnin H, Pandit P, Petty T, Baker C, Romeo T, Babitzke P. CsrA of Bacillus subtilis regulates translation initiation of the gene encoding the flagellin protein (hag) by blocking ribosome binding. Mol Microbiol. 2007;64:1605-20 pubmed publisher..Toeprint and cell-free translation studies demonstrate that bound CsrA prevents ribosome binding to the hag transcript, thereby inhibiting translation initiation and Hag synthesis...
- Shashikant C, Bolanowsky S, Anand S, Anderson S. Comparison of diverged Hoxc8 early enhancer activities reveals modification of regulatory interactions at conserved cis-acting elements. J Exp Zool B Mol Dev Evol. 2007;308:242-9 pubmed..Our finding that the enhancer elements do not act in a unitary fashion but function in the context of the surrounding sequence brings a new dimension to the study of cis-regulatory evolution. ..
- Clark A, Wang L, Hulleberg T. P-element-induced variation in metabolic regulation in Drosophila. Genetics. 1995;139:337-48 pubmed
- Arner R, Prabhu K, Thompson J, Hildenbrandt G, Liken A, Reddy C. myo-Inositol oxygenase: molecular cloning and expression of a unique enzyme that oxidizes myo-inositol and D-chiro-inositol. Biochem J. 2001;360:313-20 pubmed..Thus an understanding of the regulation of MIOX expression clearly represents a potential window on the aetiology of diabetes as well as on the control of various intracellular phosphoinositides and key signalling pathways. ..
- Clark A, Leicht B, Muse S. Length variation and secondary structure of introns in the Mlc1 gene in six species of Drosophila. Mol Biol Evol. 1996;13:471-82 pubmed..Relative rate tests also suggest a retardation in the rate of Mlc1 sequence evolution in the simulans clade. ..
- Zolfaghari R, Ross A. Lecithin:retinol acyltransferase from mouse and rat liver. CDNA cloning and liver-specific regulation by dietary vitamin a and retinoic acid. J Lipid Res. 2000;41:2024-34 pubmed
- Nelson K, Selander R. Evolutionary genetics of the proline permease gene (putP) and the control region of the proline utilization operon in populations of Salmonella and Escherichia coli. J Bacteriol. 1992;174:6886-95 pubmed..It is suggested that the recombination rate varies among genes in relation to functional type, being highest for genes encoding cell surface and other proteins for which there is an adaptive advantage in structural diversity. ..
- Meyer B, Pray Grant M, Vanden Heuvel J, Perdew G. Hepatitis B virus X-associated protein 2 is a subunit of the unliganded aryl hydrocarbon receptor core complex and exhibits transcriptional enhancer activity. Mol Cell Biol. 1998;18:978-88 pubmed..XAP2 enhanced the ability of endogenous murine and human AhR complexes to activate a dioxin-responsive element-luciferase reporter twofold, following transient expression of XAP2 in Hepa 1c1c7 and HeLa cells. ..